KEGG   ORTHOLOGY: K06458
Entry
K06458                      KO                                     

Name
CD8A
Definition
T-cell surface glycoprotein CD8 alpha chain
Pathway
ko04514  Cell adhesion molecules
ko04612  Antigen processing and presentation
ko04640  Hematopoietic cell lineage
ko04660  T cell receptor signaling pathway
ko05135  Yersinia infection
ko05340  Primary immunodeficiency
Disease
H00093  Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
   04612 Antigen processing and presentation
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
   04660 T cell receptor signaling pathway
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
  09163 Immune disease
   05340 Primary immunodeficiency
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06458  CD8A; T-cell surface glycoprotein CD8 alpha chain
CD molecules [BR:ko04090]
 Proteins
  K06458  CD8a; CD8 antigen, alpha polypeptide (p32)
Other DBs
GO: 0042288
Genes
HSA: 925(CD8A)
PTR: 735755(CD8A)
PPS: 100968474(CD8A)
GGO: 101137523(CD8A) 115933449
PON: 100454128(CD8A)
NLE: 100587295(CD8A)
MCC: 698329(CD8A)
MCF: 102124337(CD8A)
CSAB: 103241361(CD8A)
RRO: 104674168(CD8A)
RBB: 108518880(CD8A)
CJC: 100387674(CD8A)
SBQ: 101045342(CD8A)
MMU: 12525(Cd8a)
MCAL: 110296743(Cd8a)
MPAH: 110317311(Cd8a)
RNO: 24930(Cd8a)
MUN: 110562260(Cd8a)
CGE: 100766512(Cd8a)
NGI: 103737047(Cd8a)
HGL: 101720748(Cd8a)
CCAN: 109700610(Cd8a)
OCU: 100356269(CD8A)
TUP: 102471700(CD8A)
CFA: 403157(CD8A)
VVP: 112916808(CD8A)
AML: 100483271(CD8A)
UMR: 103671471(CD8A)
UAH: 113242873(CD8A)
ORO: 101363093(CD8A)
ELK: 111148035
FCA: 493799(CD8A)
PTG: 102963003(CD8A)
PPAD: 109252944 109264203(CD8A)
AJU: 106978153(CD8A)
BTA: 281060(CD8A)
BOM: 102270119(CD8A)
BIU: 109566151(CD8A)
BBUB: 102409928(CD8A)
CHX: 102185010(CD8A)
OAS: 101103464(CD8A)
SSC: 396627(CD8A)
CFR: 102503671(CD8A)
CDK: 105104175(CD8A)
BACU: 103013335(CD8A)
LVE: 103071339(CD8A)
OOR: 101285165(CD8A)
DLE: 111165407(CD8A)
PCAD: 102977953(CD8A)
ECB: 100066774(CD8A)
EPZ: 103549981(CD8A)
EAI: 106838579(CD8A)
MYB: 102255339(CD8A)
MYD: 102765507(CD8A)
MNA: 107528628(CD8A)
HAI: 109375918(CD8A)
DRO: 112302983(CD8A)
PALE: 102883844(CD8A)
RAY: 107505973(CD8A)
MJV: 108404571(CD8A)
LAV: 100654262(CD8A)
TMU: 101343469
MDO: 100029709(CD8A)
SHR: 100916690(CD8A)
PCW: 110196316(CD8A)
OAA: 103171162(CD8A)
APLA: 106020280(CD8A) 113843507
ACYG: 106033980(CD8A)
LSR: 116184800
SCAN: 103826105
GFR: 102039671(CD8A) 106632204
FAB: 101813954(CD8A)
PHI: 102114216
PMAJ: 107202899(CD8A)
CCAE: 111945871
CCW: 104690933
FPG: 101922807(CD8A)
FCH: 102050195(CD8A)
CLV: 102085944(CD8A)
NNI: 104018536(CD8A)
ACUN: 113479161(CD8A)
PADL: 103923509(CD8A)
AAM: 106484891(CD8A)
ASN: 102374072(CD8A)
AMJ: 102576858(CD8A)
PSS: 102461111(CD8A)
CMY: 102938111(CD8A)
CPIC: 101934227 103306203(CD8A)
ACS: 103279200(cd8a)
PVT: 110080255(CD8A)
PBI: 103049153(CD8A)
PMUR: 107302422(CD8A)
TSR: 106543056(CD8A)
PMUA: 114582039(CD8A)
GJA: 107120084
XTR: 100489117
NPR: 108796883(CD8A)
DRE: 677754(cd8a)
SRX: 107754627(cd8a)
SANH: 107662903 107665235(cd8a)
SGH: 107600904
CCAR: 109054692
IPU: 100415908
PHYP: 113535635
AMEX: 103029511
EEE: 113573763
TRU: 777995(cd8a)
LCO: 104928930
NCC: 104964855(cd8a)
MZE: 101470971
ONL: 100709685
OLA: 100125537
XMA: 102231708(cd8a)
XCO: 114135897(cd8a)
PRET: 103465012
CVG: 107091400(cd8a)
NFU: 107385466
KMR: 108239852(cd8a)
AOCE: 111581187(cd8a)
CSEM: 103386426
POV: 109629072(cd8a)
LCF: 108899674
SDU: 111221519(cd8a)
SLAL: 111670940(cd8a)
HCQ: 109522421
BPEC: 110174221
MALB: 109956149(cd8a)
SASA: 100136450
OTW: 112255519
SALP: 111970654
ELS: 105016775(cd8a)
SFM: 108928573(cd8a)
PKI: 111843814(cd8a)
CMK: 103181487
RTP: 109914758(cd8a)
 » show all
Reference
PMID:2496167
  Authors
Norment AM, Lonberg N, Lacy E, Littman DR
  Title
Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.
  Journal
J Immunol 142:3312-9 (1989)
  Sequence
[hsa:925]
Reference
  Authors
Gibbings DJ, Marcet-Palacios M, Sekar Y, Ng MC, Befus AD
  Title
CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
  Journal
BMC Immunol 8:12 (2007)
DOI:10.1186/1471-2172-8-12

KEGG   ORTHOLOGY: K06459
Entry
K06459                      KO                                     

Name
CD8B
Definition
T-cell surface glycoprotein CD8 beta chain
Pathway
ko04514  Cell adhesion molecules
ko04612  Antigen processing and presentation
ko04640  Hematopoietic cell lineage
ko04660  T cell receptor signaling pathway
ko05135  Yersinia infection
ko05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
   04612 Antigen processing and presentation
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
   04660 T cell receptor signaling pathway
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
  09163 Immune disease
   05340 Primary immunodeficiency
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06459  CD8B; T-cell surface glycoprotein CD8 beta chain
CD molecules [BR:ko04090]
 Proteins
  K06459  CD8b, CD8B1; CD8 antigen, beta polypeptide 1 (p37)
Other DBs
GO: 0042288
Genes
HSA: 926(CD8B) 927(CD8B2)
PTR: 470426(CD8B)
PPS: 100969045(CD8B)
GGO: 101135360(CD8B)
PON: 100451669(CD8B)
NLE: 100599814(CD8B)
MCC: 699409(CD8B)
MCF: 102122433(CD8B)
CSAB: 103241359(CD8B)
RRO: 104674169(CD8B)
RBB: 108518881(CD8B)
CJC: 100413968(CD8B)
SBQ: 101044254(CD8B)
MMU: 12526(Cd8b1)
MCAL: 110296888(Cd8b)
MPAH: 110316834(Cd8b)
RNO: 24931(Cd8b)
MUN: 110562253(Cd8b)
CGE: 100769972(Cd8b)
NGI: 103737046(Cd8b)
HGL: 101720046(Cd8b)
CCAN: 109700591(Cd8b)
OCU: 100355767(CD8B)
TUP: 102471277(CD8B)
CFA: 483076(CD8B)
VVP: 112916657(CD8B)
AML: 100484695(CD8B)
UMR: 103671473(CD8B)
UAH: 113242866(CD8B)
ORO: 101363583(CD8B)
ELK: 111148090
FCA: 493948(CD8B)
PTG: 102963282(CD8B)
PPAD: 109264221(CD8B)
AJU: 106978154(CD8B)
BTA: 508633(CD8B)
BOM: 102273155(CD8B)
BIU: 109566150(CD8B)
BBUB: 102409598(CD8B)
CHX: 102184733(CD8B)
OAS: 101103712(CD8B)
SSC: 396636(CD8B)
CFR: 102524436(CD8B)
CDK: 105104194(CD8B)
BACU: 102997870(CD8B)
LVE: 103070879(CD8B)
OOR: 101284904(CD8B)
DLE: 111165417(CD8B)
PCAD: 102977193(CD8B)
ECB: 100052855(CD8B)
EPZ: 103549979(CD8B)
EAI: 106838577(CD8B)
MYB: 102253846(CD8B)
MYD: 102756676(CD8B)
MNA: 107528645(CD8B)
HAI: 109376834(CD8B)
DRO: 112302981(CD8B)
PALE: 102884096(CD8B)
RAY: 107505939(CD8B)
MJV: 108404569(CD8B)
TMU: 101358886
MDO: 100272160(CD8B)
SHR: 100916427(CD8B)
PCW: 110196317(CD8B)
GGA: 396175(CD8B)
MGP: 100550897(CD8B)
CJO: 107314067(CD8B)
NMEL: 110398261(CD8B)
APLA: 101802256(CD8B)
ACYG: 106033965
TGU: 100231108(CD8B)
LSR: 110473280(CD8B)
SCAN: 103826104(CD8B)
GFR: 102037506(CD8B)
FAB: 101821857(CD8B)
PHI: 102102059(CD8B)
PMAJ: 107203434(CD8B)
CCAE: 111928309(CD8B)
CCW: 104690811(CD8B)
ETL: 114067218(CD8B)
FPG: 101918537(CD8B)
FCH: 102057666(CD8B)
CLV: 102086129(CD8B)
EGZ: 104135260(CD8B)
NNI: 104018535(CD8B)
ACUN: 113479360(CD8B)
PADL: 103923508(CD8B)
AAM: 106484893(CD8B)
ASN: 102373828(CD8B)
AMJ: 106737144(CD8B)
PSS: 102449968(CD8B)
CMY: 102935608(CD8B)
CPIC: 101951323(CD8B)
XLA: 100529233(cd8b.S)
XTR: 101733278(cd8b)
DRE: 100006534(si:dkey-184p9.9)
IPU: 100305022
PHYP: 113535604
AMEX: 103030369
TRU: 100126184(cd8beta)
LCO: 104928931
NCC: 104964854
MZE: 101471246
ONL: 100689918
OLA: 101173540
XMA: 102231445
XCO: 114135898
PRET: 103465013
CVG: 107091404
NFU: 107385463
KMR: 108239838(cd8b)
ALIM: 106523581
AOCE: 111581205
CSEM: 103386631
POV: 109629104
LCF: 108899675
SDU: 111221799
SLAL: 111670939
MALB: 109956168
SFM: 108939017
PKI: 111839360
LCM: 102351195(CD8B)
 » show all
Reference
PMID:3145195
  Authors
Norment AM, Littman DR
  Title
A second subunit of CD8 is expressed in human T cells.
  Journal
EMBO J 7:3433-9 (1988)
DOI:10.1002/j.1460-2075.1988.tb03217.x
  Sequence
[hsa:926]

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