KEGG   ORTHOLOGY: K06490
Entry
K06490                      KO                                     

Name
ICAM1, CD54
Definition
intercellular adhesion molecule 1
Pathway
ko04064  NF-kappa B signaling pathway
ko04514  Cell adhesion molecules
ko04650  Natural killer cell mediated cytotoxicity
ko04668  TNF signaling pathway
ko04670  Leukocyte transendothelial migration
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05143  African trypanosomiasis
ko05144  Malaria
ko05150  Staphylococcus aureus infection
ko05164  Influenza A
ko05166  Human T-cell leukemia virus 1 infection
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05169  Epstein-Barr virus infection
ko05323  Rheumatoid arthritis
ko05416  Viral myocarditis
ko05417  Lipid and atherosclerosis
ko05418  Fluid shear stress and atherosclerosis
Disease
H00083  Allograft rejection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04668 TNF signaling pathway
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04670 Leukocyte transendothelial migration
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05164 Influenza A
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05169 Epstein-Barr virus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09174 Infectious disease: parasitic
   05144 Malaria
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05143 African trypanosomiasis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09163 Immune disease
   05323 Rheumatoid arthritis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05418 Fluid shear stress and atherosclerosis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05416 Viral myocarditis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04090 CD molecules
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   00536 Glycosaminoglycan binding proteins
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04091 Lectins
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K06490  ICAM1, CD54; intercellular adhesion molecule 1
CD molecules [BR:ko04090]
 Proteins
  K06490  CD54, ICAM1; intercellular adhesion molecule 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K06490  ICAM1, CD54; intercellular adhesion molecule 1
Lectins [BR:ko04091]
 I-type lectins (Siglecs)
  K06490  ICAM1, CD54; intercellular adhesion molecule 1
Genes
HSA: 3383(ICAM1)
PTR: 450196(ICAM1)
PPS: 100980120(ICAM1)
GGO: 101127502(ICAM1)
PON: 100437727(ICAM1)
NLE: 100593834(ICAM1)
MCC: 712280(ICAM1)
MCF: 102138837(ICAM1)
CSAB: 103233893(ICAM1)
RRO: 104670485(ICAM1)
RBB: 108534474(ICAM1)
CJC: 100393866(ICAM1)
SBQ: 101054438(ICAM1)
MMU: 15894(Icam1)
MCAL: 110301325(Icam1)
MPAH: 110327515(Icam1)
RNO: 25464(Icam1)
MUN: 110555772(Icam1)
CGE: 100689428(Icam1)
NGI: 103747569(Icam1)
HGL: 101713679(Icam1)
CCAN: 109693172(Icam1)
OCU: 100345640(ICAM1)
TUP: 102497624(ICAM1)
CFA: 403975(ICAM1)
VVP: 112909640(ICAM1)
AML: 100476475(ICAM1)
UMR: 103678731(ICAM1)
UAH: 113242979(ICAM1)
ORO: 101375646(ICAM1)
ELK: 111162530
FCA: 101089421(ICAM1)
PTG: 102969345(ICAM1)
PPAD: 109254118(ICAM1)
AJU: 106980319(ICAM1)
BTA: 281839(ICAM1)
BIU: 109561581
BBUB: 102412194 102412516(ICAM1)
CHX: 102181113(ICAM1)
OAS: 443045(ICAM1)
SSC: 396750(ICAM1)
CFR: 102509968(ICAM1)
CDK: 105087642(ICAM1)
BACU: 103020269(ICAM1)
LVE: 103079699(ICAM1)
OOR: 101276958(ICAM1)
DLE: 111166053(ICAM1)
PCAD: 102988478(ICAM1)
ECB: 100058207(ICAM1)
EPZ: 103558066(ICAM1)
EAI: 106841519(ICAM1)
MYB: 102255343(ICAM1)
MYD: 102767600(ICAM1)
MNA: 107533247(ICAM1)
HAI: 109391654(ICAM1)
DRO: 112301541(ICAM1)
PALE: 102897326(ICAM1)
RAY: 107515099(ICAM1)
MJV: 108397119
LAV: 100673685(ICAM1)
TMU: 101343257
SHR: 100933797(ICAM1)
PCW: 110214227
ASN: 102381642
PSS: 102449607
CPIC: 101952253
SANH: 107670523
SLAL: 111651278
PKI: 111849269
 » show all
Reference
PMID:3340213
  Authors
Simmons D, Makgoba MW, Seed B
  Title
ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM.
  Journal
Nature 331:624-7 (1988)
DOI:10.1038/331624a0
  Sequence
[hsa:3383]
Reference
  Authors
Braun M, Pietsch P, Schror K, Baumann G, Felix SB
  Title
Cellular adhesion molecules on vascular smooth muscle cells.
  Journal
Cardiovasc Res 41:395-401 (1999)
DOI:10.1016/S0008-6363(98)00302-2

KEGG   ORTHOLOGY: K06523
Entry
K06523                      KO                                     

Name
ICAM2, CD102
Definition
intercellular adhesion molecule 2
Pathway
ko04514  Cell adhesion molecules
ko04650  Natural killer cell mediated cytotoxicity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06523  ICAM2, CD102; intercellular adhesion molecule 2
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06523  ICAM2, CD102; intercellular adhesion molecule 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06523  ICAM2, CD102; intercellular adhesion molecule 2
   04091 Lectins
    K06523  ICAM2, CD102; intercellular adhesion molecule 2
CD molecules [BR:ko04090]
 Proteins
  K06523  CD102, ICAM2; intercellular adhesion molecule 2
Lectins [BR:ko04091]
 I-type lectins (Siglecs)
  K06523  ICAM2, CD102; intercellular adhesion molecule 2
Genes
HSA: 3384(ICAM2)
PTR: 494137(ICAM2)
PPS: 100973952(ICAM2)
GGO: 101130366(ICAM2)
PON: 100450429(ICAM2)
NLE: 100606770(ICAM2)
MCC: 574158(ICAM2)
MCF: 102146483(ICAM2)
CSAB: 103243209(ICAM2)
RRO: 104675450(ICAM2)
RBB: 108536260(ICAM2)
CJC: 100414504(ICAM2)
SBQ: 101042874(ICAM2)
MMU: 15896(Icam2)
MCAL: 110305577(Icam2)
MPAH: 110332367(Icam2)
RNO: 360647(Icam2)
MUN: 110547063(Icam2)
CGE: 100750973(Icam2)
NGI: 103744744(Icam2)
HGL: 101713583(Icam2)
CCAN: 109681628
OCU: 100356584(ICAM2)
TUP: 102471945(ICAM2)
CFA: 480475(ICAM2)
VVP: 112920711(ICAM2)
AML: 100474729(ICAM2)
UMR: 103665640(ICAM2)
UAH: 113265276(ICAM2)
ORO: 101381675(ICAM2)
ELK: 111158135
FCA: 101098907(ICAM2)
PTG: 102955255(ICAM2)
PPAD: 109277088(ICAM2)
AJU: 106978698(ICAM2)
BIU: 109573936(ICAM2) 109573938
SSC: 414387(ICAM2)
CFR: 102506520(ICAM2) 116656647
CDK: 105090397 105104572(ICAM2)
BACU: 103016676(ICAM2)
LVE: 103078665(ICAM2)
OOR: 101288922(ICAM2)
DLE: 111182624(ICAM2)
PCAD: 102979956(ICAM2)
ECB: 100064400(ICAM2)
EPZ: 103549753(ICAM2)
EAI: 106835538(ICAM2)
MYB: 102251851(ICAM2)
MYD: 102774168(ICAM2)
MNA: 107531104(ICAM2)
HAI: 109380328(ICAM2)
DRO: 112316333(ICAM2)
PALE: 102897030(ICAM2)
RAY: 107502005(ICAM2)
MJV: 108403390
LAV: 100668478(ICAM2) 100669035
TMU: 101352703
MDO: 100026400(ICAM2)
SHR: 100935139(ICAM2)
PCW: 110219322(ICAM2)
AMJ: 102576680(ICAM2)
GJA: 107121972
XTR: 108644500
IPU: 108257019(icam2) 108257178
SASA: 106599505
RTP: 109918973
 » show all
Reference
PMID:2497351
  Authors
Staunton DE, Dustin ML, Springer TA
  Title
Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1.
  Journal
Nature 339:61-4 (1989)
DOI:10.1038/339061a0
  Sequence
[hsa:3384]
Reference
  Authors
Kotovuori A, Pessa-Morikawa T, Kotovuori P, Nortamo P, Gahmberg CG
  Title
ICAM-2 and a peptide from its binding domain are efficient activators of leukocyte adhesion and integrin affinity.
  Journal
J Immunol 162:6613-20 (1999)

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