KEGG   ORTHOLOGY: K06516
Entry
K06516                      KO                                     

Name
KLRD1, CD94
Definition
killer cell lectin-like receptor subfamily D member 1
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
   04612 Antigen processing and presentation
    K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
   04091 Lectins
    K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
CD molecules [BR:ko04090]
 Proteins
  K06516  CD94, KLRD1; killer cell lectin-like receptor subfamily D, member 1
Lectins [BR:ko04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   K06516  KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
Genes
HSA: 3824(KLRD1)
PTR: 450156(KLRD1)
PPS: 100992162(KLRD1)
GGO: 101124666(KLRD1)
PON: 100458827(KLRD1)
NLE: 100606121(KLRD1)
MCC: 574145(KLRD1)
MCF: 102119829(KLRD1)
CSAB: 103218580(KLRD1)
RRO: 104668620(KLRD1)
RBB: 108542154(KLRD1)
CJC: 100399584(KLRD1)
SBQ: 101045904(KLRD1)
MMU: 16643(Klrd1)
MCAL: 110296891
MPAH: 110317106
RNO: 25110(Klrd1)
MUN: 110553445
CGE: 100773640
HGL: 101711887(Klrd1)
CCAN: 109689715
OCU: 103348990
TUP: 102484529(KLRD1)
CFA: 611360(KLRD1)
VVP: 112917501(KLRD1)
AML: 105234734(KLRD1)
UMR: 103669132(KLRD1)
UAH: 113257897(KLRD1)
ORO: 101367599(KLRD1)
ELK: 111142226
FCA: 101086731(KLRD1)
PTG: 102966502(KLRD1)
PPAD: 109259093(KLRD1)
AJU: 106965721(KLRD1)
BTA: 444877(KLRD1) 618565
SSC: 100622915(KLRD1)
CFR: 102512731
CDK: 105094218
BACU: 103008245(KLRD1)
LVE: 103091175(KLRD1)
OOR: 101276292(KLRD1)
DLE: 111176759(KLRD1)
ECB: 100062540(KLRD1)
EPZ: 103542182
EAI: 106837403
MYB: 102242242
MYD: 102759535(KLRD1)
MNA: 107543998
PALE: 102880995(KLRD1) 102885748
MJV: 108388082
MGP: 100544943
CJO: 107319361
 » show all
Reference
PMID:7589107
  Authors
Chang C, Rodriguez A, Carretero M, Lopez-Botet M, Phillips JH, Lanier LL
  Title
Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily.
  Journal
Eur J Immunol 25:2433-7 (1995)
DOI:10.1002/eji.1830250904
  Sequence
[hsa:3824]
Reference
PMID:9486650
  Authors
Braud VM, Allan DS, O'Callaghan CA, Soderstrom K, D'Andrea A, Ogg GS, Lazetic S, Young NT, Bell JI, Phillips JH, Lanier LL, McMichael AJ
  Title
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
  Journal
Nature 391:795-9 (1998)
DOI:10.1038/35869

KEGG   ORTHOLOGY: K06541
Entry
K06541                      KO                                     

Name
KLRC1, NKG2A
Definition
killer cell lectin-like receptor subfamily C1
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
   04612 Antigen processing and presentation
    K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
   04091 Lectins
    K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
CD molecules [BR:ko04090]
 Proteins
  K06541  CD159a, KLRC1; killer cell lectin-like receptor subfamily C, member 1
Lectins [BR:ko04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   K06541  KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
Genes
HSA: 3821(KLRC1)
PTR: 101058094 450131(KLRC1)
PPS: 100990924(KLRC1)
GGO: 101127319(KLRC1)
PON: 100459565(KLRC1)
NLE: 100607694
MCC: 574146(KLRC1)
MCF: 102121106(KLRC1)
CSAB: 103218588(KLRC1)
RRO: 104668626(KLRC1)
RBB: 108542130
CJC: 100397660(KLRC1)
SBQ: 101046441(KLRC1)
MMU: 16641(Klrc1)
MCAL: 110296690
RNO: 29683(Klrc1)
NGI: 103729807
HGL: 101713681(Klrc1)
CCAN: 109692062
OCU: 100337728
TUP: 102494129
SSC: 100523789
CFR: 102521616
CDK: 105094220
BACU: 103007543
LVE: 103074952(KLRC1)
OOR: 101276044
DLE: 111176758
MJV: 108383397
 » show all
Reference
PMID:2007850
  Authors
Houchins JP, Yabe T, McSherry C, Bach FH
  Title
DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.
  Journal
J Exp Med 173:1017-20 (1991)
DOI:10.1084/jem.173.4.1017
  Sequence
[hsa:3821]
Reference
PMID:9486650
  Authors
Braud VM, Allan DS, O'Callaghan CA, Soderstrom K, D'Andrea A, Ogg GS, Lazetic S, Young NT, Bell JI, Phillips JH, Lanier LL, McMichael AJ
  Title
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C.
  Journal
Nature 391:795-9 (1998)
DOI:10.1038/35869

KEGG   ORTHOLOGY: K24233
Entry
K24233                      KO                                     

Name
KLRC2_3, NKG2C_E
Definition
killer cell lectin-like receptor subfamily C2/3
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K24233  KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
   04612 Antigen processing and presentation
    K24233  KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K24233  KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
   04091 Lectins
    K24233  KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
CD molecules [BR:ko04090]
 Proteins
  K24233  CD159c, KLRC2; killer cell lectin-like receptor subfamily C, member 2
Lectins [BR:ko04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   K24233  KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
Genes
HSA: 3822(KLRC2) 3823(KLRC3)
PTR: 107973221 449624(KLRC3) 450132(KLRC2)
PPS: 100990352(KLRC2) 100991458(KLRC3)
GGO: 101128183
PON: 100460184
MCC: 114670780(KLRC2)
MCF: 102132533
CSAB: 103218582
RRO: 104668625
RBB: 108542146
CJC: 100398258(KLRC2)
SBQ: 101047280
 » show all
Reference
PMID:2007850
  Authors
Houchins JP, Yabe T, McSherry C, Bach FH
  Title
DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells.
  Journal
J Exp Med 173:1017-20 (1991)
DOI:10.1084/jem.173.4.1017
  Sequence
[hsa:3822]
Reference
PMID:8276468
  Authors
Adamkiewicz TV, McSherry C, Bach FH, Houchins JP
  Title
Natural killer lectin-like receptors have divergent carboxy-termini, distinct from C-type lectins.
  Journal
Immunogenetics 39:218 (1994)
DOI:10.1007/BF00241264
  Sequence
[hsa:3823]

KEGG   ORTHOLOGY: K24234
Entry
K24234                      KO                                     

Name
KLRC4, NKG2F
Definition
killer cell lectin-like receptor subfamily C4
Pathway
ko04612  Antigen processing and presentation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K24234  KLRC4, NKG2F; killer cell lectin-like receptor subfamily C4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04091 Lectins
    K24234  KLRC4, NKG2F; killer cell lectin-like receptor subfamily C4
Lectins [BR:ko04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   K24234  KLRC4, NKG2F; killer cell lectin-like receptor subfamily C4
Genes
HSA: 8302(KLRC4)
PTR: 450145(KLRC4)
PPS: 100991809(KLRC4)
GGO: 101126945
PON: 100459192
NLE: 101178428
RBB: 108542145
TUP: 106736213(KLRC4)
Reference
PMID:9394807
  Authors
Plougastel B, Trowsdale J
  Title
Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes.
  Journal
Eur J Immunol 27:2835-9 (1997)
DOI:10.1002/eji.1830271114
  Sequence
[hsa:8302]

KEGG   ORTHOLOGY: K07980
Entry
K07980                      KO                                     

Name
KIR3DL, CD158
Definition
killer cell immunoglobulin-like receptor 3DL
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07980  KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
   04612 Antigen processing and presentation
    K07980  KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K07980  KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K07980  KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
CD molecules [BR:ko04090]
 Proteins
  K07980  CD158e, KIR3DL1; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
  K07980  CD158k, KIR3DL2; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
Other DBs
GO: 0030109
Genes
HSA: 115653(KIR3DL3) 3811(KIR3DL1) 3812(KIR3DL2)
PTR: 100125359(KIR3DL5) 100608180 107972950 456289(KIR3DX1) 456291(KIR3DL1)
PPS: 100987319(KIR2DL1) 100992623 100994016(KIR3DL3) 103784706(KIR3DL2)
GGO: 101123869 109024094 115930123 115931563 115931566 115933440
PON: 100432983 100435483 100437736 100936383 100936826
NLE: 100587156(KIR3DL2) 100592754 100594804(KIR3DL3) 100595837 100600482 101176722
MCC: 100125559(KIR3DL2) 100125560(KIR3DL12) 100125563(KIR3DH5) 100125567(MAMU-KIR) 100125571(KIR3DS05) 100125572 100125574(KIR3DL1) 100125577(KIR3DL11) 106994859 114669735 696175(KIR3DL0) 722783(KIR3DL21) 735306(KIR3DH)
MCF: 102114867 102115251 102116019 102116779 102120587 102144764(KIR2DL3)
CSAB: 103235271 103235272 103235277 103235278 103235279 103235280 103235281 103235478
RRO: 104672221 104674750 104675306 104675314 104675316 104681114
CJC: 100414135
MMU: 245615(Kir3dl2) 245616(Kir3dl1)
RNO: 353253(Kir3dl1)
CGE: 107979912
NGI: 103729714(Kir2dl4) 103744699
CCAN: 109685401
TUP: 102477320
AML: 100470457
UAH: 113247403
ORO: 101383210
FCA: 101084434
PTG: 102960738(KIR3DL2)
AJU: 106980871(KIR3DL3)
BTA: 100852061 353254(KIR3DL1) 493736(KIR3DS1) 537065(KIR3DL2) 614781
BIU: 109571857
CFR: 102513525
CDK: 105106334
ECB: 100034224(KIR3DL)
EPZ: 103554711
EAI: 106840882 106840907(KIR3DL)
DRO: 112313840
MJV: 108384182
TMU: 101359741
 » show all
Reference
PMID:7716543
  Authors
Colonna M, Samaridis J
  Title
Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.
  Journal
Science 268:405-8 (1995)
DOI:10.1126/science.7716543
  Sequence
[hsa:3811 3812]
Reference
  Authors
Campbell KS, Purdy AK
  Title
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations.
  Journal
Immunology 132:315-25 (2011)
DOI:10.1111/j.1365-2567.2010.03398.x

KEGG   ORTHOLOGY: K07981
Entry
K07981                      KO                                     

Name
KIR2DL1_2_3, CD158A_B
Definition
killer cell immunoglobulin-like receptor 2DL1/2/3
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
   04612 Antigen processing and presentation
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
CD molecules [BR:ko04090]
 Proteins
  K07981  CD158a, KIR2DL1; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  K07981  CD158b1, KIR2DL2; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
  K07981  CD158b2, KIR2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
Genes
HSA: 3802(KIR2DL1) 3803(KIR2DL2) 3804(KIR2DL3)
PTR: 750609(KIR2DL3)
GGO: 115933447
PON: 100437371
CSAB: 103235276
Reference
PMID:7716543
  Authors
Colonna M, Samaridis J
  Title
Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.
  Journal
Science 268:405-8 (1995)
DOI:10.1126/science.7716543
  Sequence
[hsa:3802 3804]
Reference
  Authors
Campbell KS, Purdy AK
  Title
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations.
  Journal
Immunology 132:315-25 (2011)
DOI:10.1111/j.1365-2567.2010.03398.x

KEGG   ORTHOLOGY: K24231
Entry
K24231                      KO                                     

Name
KIR2DL4, CD158D
Definition
killer cell immunoglobulin-like receptor 2DL4
Pathway
ko04218  Cellular senescence
ko04612  Antigen processing and presentation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    K24231  KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K24231  KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K24231  KIR2DL4, CD158D; killer cell immunoglobulin-like receptor 2DL4
CD molecules [BR:ko04090]
 Proteins
  K24231  CD158d, KIR2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
Genes
HSA: 3805(KIR2DL4)
PTR: 450205(KIR2DL4)
MCC: 722782(KIR2DL4)
RRO: 104675319(KIR2DL4)
CHX: 102168342
Reference
PMID:8946682
  Authors
Selvakumar A, Steffens U, Dupont B
  Title
NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains.
  Journal
Tissue Antigens 48:285-94 (1996)
DOI:10.1111/j.1399-0039.1996.tb02647.x
  Sequence
[hsa:3805]

KEGG   ORTHOLOGY: K24232
Entry
K24232                      KO                                     

Name
KIR2DL5, CD158F
Definition
killer cell immunoglobulin-like receptor 2DL5
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
   04612 Antigen processing and presentation
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
CD molecules [BR:ko04090]
 Proteins
  K24232  CD158f1, KIR2DL5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5
Genes
HSA: 57292(KIR2DL5A)
PTR: 107969810
PPS: 100986982
GGO: 115933442
PON: 100936503
BTA: 282860(KIR2DL5A)
BOM: 102280334
BBUB: 102402612
Reference
  Authors
Vilches C, Rajalingam R, Uhrberg M, Gardiner CM, Young NT, Parham P
  Title
KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.
  Journal
J Immunol 164:5797-804 (2000)
DOI:10.4049/jimmunol.164.11.5797
  Sequence
[hsa:57292]

KEGG   ORTHOLOGY: K07982
Entry
K07982                      KO                                     

Name
KIR2DS, CD158
Definition
killer cell immunoglobulin-like receptor 2DS
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07982  KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
   04612 Antigen processing and presentation
    K07982  KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K07982  KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
CD molecules [BR:ko04090]
 Proteins
  K07982  CD158g, KIR2DS5; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
  K07982  CD158h, KIR2DS1; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
  K07982  CD158i, KIR2DS4; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
  K07982  CD158j, KIR2DS2; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
Genes
HSA: 100132285(KIR2DS2) 3806(KIR2DS1) 3808(KIR2DS3) 3809(KIR2DS4) 3810(KIR2DS5)
BTA: 493737(KIR2DS1)
Reference
PMID:7749980
  Authors
Wagtmann N, Biassoni R, Cantoni C, Verdiani S, Malnati MS, Vitale M, Bottino C, Moretta L, Moretta A, Long EO
  Title
Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.
  Journal
Immunity 2:439-49 (1995)
DOI:10.1016/1074-7613(95)90025-X
  Sequence
Reference
  Authors
Campbell KS, Purdy AK
  Title
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations.
  Journal
Immunology 132:315-25 (2011)
DOI:10.1111/j.1365-2567.2010.03398.x

DBGET integrated database retrieval system