KEGG   ORTHOLOGY: K06550
Entry
K06550                      KO                                     
Symbol
L1CAM, CD171
Name
L1 cell adhesion molecule
Pathway
map04360  Axon guidance
map04514  Cell adhesion molecules
Disease
H00266  Hereditary spastic paraplegia
H01034  L1 syndrome
H02178  MASA syndrome
H02458  Hydrocephalus due to congenital stenosis of aqueduct of Sylvius
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06550  L1CAM, CD171; L1 cell adhesion molecule
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K06550  L1CAM, CD171; L1 cell adhesion molecule
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules
    K06550  L1CAM, CD171; L1 cell adhesion molecule
   04090 CD molecules
    K06550  L1CAM, CD171; L1 cell adhesion molecule
   04091 Lectins
    K06550  L1CAM, CD171; L1 cell adhesion molecule
Cell adhesion molecules [BR:ko04515]
 Immunoglobulin superfamily
  L1 family
   K06550  L1CAM, CD171; L1 cell adhesion molecule
CD molecules [BR:ko04090]
 Proteins
  K06550  CD171, L1CAM; L1 cell adhesion molecule (MASA syndrome, spastic paraplegia 1)
Lectins [BR:ko04091]
 I-type lectins (Siglecs)
  K06550  L1CAM, CD171; L1 cell adhesion molecule
Genes
HSA: 3897(L1CAM)
PTR: 450117(L1CAM)
PPS: 100970233(L1CAM)
GGO: 109025322(L1CAM)
PON: 100437141(L1CAM)
NLE: 115833207(L1CAM)
MCC: 697504(L1CAM)
MCF: 102127011(L1CAM)
CSAB: 103232804(L1CAM)
CATY: 105598725(L1CAM)
PANU: 100137550(L1CAM)
TGE: 112615068(L1CAM)
RRO: 104661172(L1CAM)
RBB: 108535072(L1CAM)
PTEH: 111531955(L1CAM)
CJC: 100406828(L1CAM)
SBQ: 101034097(L1CAM)
CSYR: 103255115(L1CAM)
MMUR: 105867318(L1CAM)
LCAT: 123628465(L1CAM)
OGA: 100949201(L1CAM)
MMU: 16728(L1cam)
MCAL: 110286936(L1cam)
MPAH: 110313446(L1cam)
RNO: 50687(L1cam)
MCOC: 116086035(L1cam)
MUN: 110560447(L1cam)
CGE: 100769119(L1cam)
MAUA: 101832859(L1cam)
PLEU: 114706196(L1cam)
AAMP: 119805033(L1cam)
NGI: 103731204(L1cam)
HGL: 101723636(L1cam)
CPOC: 100726067(L1cam)
CCAN: 109697863(L1cam)
DORD: 106000173(L1cam)
DSP: 122097047(L1cam)
NCAR: 124972447
OCU: 100328746(L1CAM)
OPI: 101522016(L1CAM)
TUP: 102474808(L1CAM)
CFA: 492244(L1CAM)
CLUD: 112668379(L1CAM)
VVP: 112911456(L1CAM)
VLG: 121483120(L1CAM)
AML: 100482790(L1CAM)
UMR: 103679695
UAH: 113247868(L1CAM)
UAR: 123797329(L1CAM)
ELK: 111139154
LLV: 125091295
MPUF: 101681066(L1CAM)
ORO: 101379544(L1CAM)
EJU: 114201630(L1CAM)
ZCA: 113931449(L1CAM)
MLX: 118014844(L1CAM)
FCA: 101088733(L1CAM)
PYU: 121025095(L1CAM)
PBG: 122477933(L1CAM)
PTG: 102971443(L1CAM)
PPAD: 109259863(L1CAM)
AJU: 106989207(L1CAM)
HHV: 120221726(L1CAM)
BTA: 516017(L1CAM)
BOM: 102274145(L1CAM)
BIU: 109555392(L1CAM)
BBUB: 102410202(L1CAM)
CHX: 102181196(L1CAM)
OAS: 101110032(L1CAM)
ODA: 120881800(L1CAM)
CCAD: 122435319(L1CAM)
SSC: 100525324(L1CAM)
CFR: 102514839(L1CAM)
CBAI: 105076076(L1CAM)
CDK: 105098724(L1CAM)
VPC: 102524770(L1CAM)
BACU: 102997249(L1CAM)
LVE: 103069277(L1CAM)
OOR: 101278883(L1CAM)
DLE: 111170600(L1CAM)
PCAD: 102977003(L1CAM)
PSIU: 116747443(L1CAM)
ECB: 100059024(L1CAM)
EAI: 106825621(L1CAM)
MYB: 102260104(L1CAM)
MYD: 102759033(L1CAM)
MMYO: 118654221(L1CAM)
MLF: 102422358(L1CAM)
MNA: 107538801(L1CAM)
PKL: 118714712(L1CAM)
HAI: 109394353(L1CAM)
DRO: 112296327(L1CAM)
SHON: 118994298(L1CAM)
AJM: 119053466(L1CAM)
PDIC: 114505017(L1CAM)
PHAS: 123823131(L1CAM)
MMF: 118636209(L1CAM)
RFQ: 117026748(L1CAM)
PALE: 102887759(L1CAM)
PGIG: 120605932(L1CAM)
PVP: 105302484(L1CAM)
MJV: 108402414(L1CAM)
TOD: 119246482(L1CAM)
SARA: 101540469(L1CAM)
LAV: 100677596(L1CAM)
TMU: 101342056
DNM: 101425639(L1CAM)
MDO: 100028028(L1CAM)
SHR: 100921023(L1CAM)
PCW: 110201525(L1CAM)
OAA: 100084300(L1CAM)
LSR: 110482559
PHI: 102106842(L1CAM)
ASN: 102384802(L1CAM)
AMJ: 102572953(L1CAM)
CPIC: 101944400
MRV: 120388585(L1CAM)
ACS: 100562604(l1cam)
PVT: 110078679(L1CAM)
SUND: 121921176(L1CAM)
PBI: 103064807(L1CAM)
PMUR: 107284224(L1CAM)
PGUT: 117675505(L1CAM)
VKO: 123030056(L1CAM)
PMUA: 114587370(L1CAM)
ZVI: 118097817(L1CAM)
GJA: 107111386
XLA: 373742(l1cam.S)
XTR: 100124734(l1cam)
NPR: 108800287
BBUF: 120977947(L1CAM)
BGAR: 122946835
DRE: 30634(l1cama)
PPRM: 120463059(l1cama)
MAMB: 125260673(l1cama)
IPU: 108275777(l1camb) 108276290(l1cama)
SMEO: 124398861(l1camb)
TFD: 113658183(l1cama)
LCO: 104932697(l1cam) 104933590
NCC: 104956932
EFO: 125892118(l1cama) 125892255
PLEP: 121946753(l1cama) 121947569
SLUC: 116039117(l1cama) 116060427(l1camb)
ECRA: 117941020 117947751(l1cama)
GAT: 120829081(l1cama)
PPUG: 119222207(l1cama) 119222513
CUD: 121516930(l1cama) 121517418
ALAT: 119022456 119023477(l1cama)
MZE: 101468157 101478519(l1cam)
ONL: 100703814(l1cam) 100712012
OAU: 116311864 116325876(l1cama)
OLA: 101164215 101166379(l1cam)
OML: 112159369 112159793(l1cama)
XMA: 102218752 102222945(l1cam)
XCO: 114140282 114144745(l1cam)
XHE: 116722218 116727067(l1cam)
PRET: 103467332(l1cam) 103468055
PFOR: 103141152(l1cam) 103153468
CTUL: 119782229(l1cama) 119799386
GMU: 124870504(l1cama) 124876034
NFU: 107390570 107390863(l1cam)
KMR: 108244600(l1cama) 108249713
NWH: 119417244 119417277(l1cama)
MCEP: 125006899(l1cama) 125010886
CSEM: 103384549 103384577(l1cam)
POV: 109630551(l1cam)
SSEN: 122777235(l1cama) 122777852
HHIP: 117764482(l1cama) 117765111
HSP: 118111261(l1cama) 118111584
SLAL: 111670621(l1cam) 111673374
XGL: 120804085 120804207(l1cama)
MALB: 109965222 109968836(l1cam)
BSPL: 114858401(l1cama) 114858805
ELS: 105013516 105013527(l1cam)
PKI: 111855301(l1cam) 111856948
AANG: 118207773(l1cama) 118211460
LOC: 102685426
ARUT: 117404274
LCM: 102354247(L1CAM)
DFR: 124498933
BGT: 106070215
GAE: 121378126
HRF: 124139705
HRJ: 124259016
PMAX: 117331542
ATEN: 116305914
XEN: 124435709
 » show all
Reference
PMID:1932117
  Authors
Kobayashi M, Miura M, Asou H, Uyemura K
  Title
Molecular cloning of cell adhesion molecule L1 from human nervous tissue: a comparison of the primary sequences of L1 molecules of different origin.
  Journal
Biochim Biophys Acta 1090:238-40 (1991)
DOI:10.1016/0167-4781(91)90108-X
  Sequence
[hsa:3897]
Reference
  Authors
Kiefel H, Bondong S, Hazin J, Ridinger J, Schirmer U, Riedle S, Altevogt P
  Title
L1CAM: a major driver for tumor cell invasion and motility.
  Journal
Cell Adh Migr 6:374-84 (2012)
DOI:10.4161/cam.20832

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