ORTHOLOGY: K06476 Help
Entry
Symbol
ITGA2B, CD41
Name
Pathway
map04613 Neutrophil extracellular trap formation
map04810 Regulation of actin cytoskeleton
map05412 Arrhythmogenic right ventricular cardiomyopathy
map05418 Fluid shear stress and atherosclerosis
Disease
H00226 Glanzmann thrombasthenia
H01235 Bleeding disorder platelet-type
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
K06476 ITGA2B, CD41; integrin alpha 2B
04151 PI3K-Akt signaling pathway
K06476 ITGA2B, CD41; integrin alpha 2B
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
K06476 ITGA2B, CD41; integrin alpha 2B
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
K06476 ITGA2B, CD41; integrin alpha 2B
09142 Cell motility
04820 Cytoskeleton in muscle cells
K06476 ITGA2B, CD41; integrin alpha 2B
04810 Regulation of actin cytoskeleton
K06476 ITGA2B, CD41; integrin alpha 2B
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
K06476 ITGA2B, CD41; integrin alpha 2B
04611 Platelet activation
K06476 ITGA2B, CD41; integrin alpha 2B
04613 Neutrophil extracellular trap formation
K06476 ITGA2B, CD41; integrin alpha 2B
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
K06476 ITGA2B, CD41; integrin alpha 2B
09162 Cancer: specific types
05222 Small cell lung cancer
K06476 ITGA2B, CD41; integrin alpha 2B
09172 Infectious disease: viral
05165 Human papillomavirus infection
K06476 ITGA2B, CD41; integrin alpha 2B
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
K06476 ITGA2B, CD41; integrin alpha 2B
05410 Hypertrophic cardiomyopathy
K06476 ITGA2B, CD41; integrin alpha 2B
05412 Arrhythmogenic right ventricular cardiomyopathy
K06476 ITGA2B, CD41; integrin alpha 2B
05414 Dilated cardiomyopathy
K06476 ITGA2B, CD41; integrin alpha 2B
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K06476 ITGA2B, CD41; integrin alpha 2B
09183 Protein families: signaling and cellular processes
04147 Exosome
K06476 ITGA2B, CD41; integrin alpha 2B
04515 Cell adhesion molecules
K06476 ITGA2B, CD41; integrin alpha 2B
04090 CD molecules
K06476 ITGA2B, CD41; integrin alpha 2B
Protein phosphatases and associated proteins [BR:ko01009 ]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
K06476 ITGA2B, CD41; integrin alpha 2B
Exosome [BR:ko04147 ]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
K06476 ITGA2B, CD41; integrin alpha 2B
Cell adhesion molecules [BR:ko04515 ]
Integrins
Integrin alpha subunits
K06476 ITGA2B, CD41; integrin alpha 2B
CD molecules [BR:ko04090 ]
Proteins
K06476 CD41, ITGA2B; integrin, alpha 2b
BRITE hierarchy
Genes
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Taxonomy UniProt
Reference
Authors
Poncz M, Eisman R, Heidenreich R, Silver SM, Vilaire G, Surrey S, Schwartz E, Bennett JS
Title
Structure of the platelet membrane glycoprotein IIb. Homology to the alpha subunits of the vitronectin and fibronectin membrane receptors.
Journal
J Biol Chem 262:8476-82 (1987)
Sequence
Reference
Authors
Ye F, Petrich BG, Anekal P, Lefort CT, Kasirer-Friede A, Shattil SJ, Ruppert R, Moser M, Fassler R, Ginsberg MH
Title
The mechanism of kindlin-mediated activation of integrin alphaIIbbeta3.
Journal