KEGG ORTHOLOGY: K06641

ORTHOLOGY: K06641

Entry

K06641                      KO

Symbol

CHEK2

Name

serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]

Pathway

map04110

Cell cycle

map04111

Cell cycle - yeast

map04115

p53 signaling pathway

map04218

Cellular senescence

map05166

Human T-cell leukemia virus 1 infection

Disease

H00020

Colorectal cancer

H00036

Osteosarcoma

H00881

Li-Fraumeni syndrome

H02624

Tumor predisposition syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
   04111 Cell cycle - yeast
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
   04115 p53 signaling pathway
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
   04218 Cellular senescence
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K06641  CHEK2; serine/threonine-protein kinase CHEK2
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K06641  CHEK2; serine/threonine-protein kinase CHEK2
Protein kinases [BR:ko01001]
Serine/threonine kinases: CAMK group
  RAD53 family
   K06641  CHEK2; serine/threonine-protein kinase CHEK2
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  Check point factors
   Other check point factors
    K06641  CHEK2; serine/threonine-protein kinase CHEK2

Other DBs

COG:

COG0515

Genes

HSA:	11200(CHEK2)

PTR:	458733(CHEK2)

PPS:	100987687(CHEK2)

GGO:	101124618(CHEK2)

PON:	100461345(CHEK2)

PPYG:

129023244(CHEK2)

NLE:	100594542(CHEK2)

HMH:	116458592(CHEK2)

SSYN:

129467949(CHEK2)

MCC:	713668(CHEK2)

MCF:	102122988(CHEK2)

MTHB:

126963968

MNI:	105487285(CHEK2)

CSAB:

103223122(CHEK2)

CATY:

105575682(CHEK2)

PANU:

101015280(CHEK2)

TGE:	112633701(CHEK2)

MLEU:

105550735(CHEK2)

RRO:	104658998(CHEK2)

RBB:	108517558(CHEK2)

TFN:	117096133(CHEK2)

PTEH:

111525354(CHEK2)

CANG:

105506620(CHEK2)

CJC:	100404949(CHEK2)

SBQ:	101051768(CHEK2)

CIMI:

108290013(CHEK2)

ANAN:

105725784(CHEK2)

CSYR:

103261071(CHEK2)

MMUR:

105870892(CHEK2)

LCAT:

123625798(CHEK2)

PCOQ:

105810166(CHEK2)

OGA:	100959652(CHEK2)

MMU:	50883(Chek2)

MCAL:

110294527(Chek2)

MPAH:

110312870(Chek2)

RNO:	114212(Chek2)

MCOC:

116068143(Chek2)

ANU:	117697671(Chek2)

MUN:	110553166(Chek2)

CGE:	100769280(Chek2)

MAUA:

101829845(Chek2)

PROB:

127215931(Chek2)

PLEU:

114685972

MORG:

121446253(Chek2)

MFOT:

126488526

AAMP:

119825027(Chek2)

NGI:	103750875(Chek2)

HGL:	101721212(Chek2)

CPOC:

100727440(Chek2)

CCAN:

109690250(Chek2)

DORD:

105984170(Chek2)

DSP:	122097162(Chek2)

PLOP:

125348986(Chek2)

NCAR:

124991831

MMMA:

107154594(Chek2)

OCU:

100339430

OPI:	101527828(CHEK2)

TUP:	102484993(CHEK2)

GVR:	103598989(CHEK2)

CFA:	486338(CHEK2)

CLUD:

112676766(CHEK2)

VVP:	112906959(CHEK2)

VLG:	121475489(CHEK2)

NPO:	129507791(CHEK2)

AML:	100467146(CHEK2)

UMR:	103659236(CHEK2)

UAH:	113244997(CHEK2)

UAR:	123788135(CHEK2)

ELK:

111160086

LLV:

125081641

MPUF:

101690611(CHEK2)

MNP:	132023294(CHEK2)

MLK:	131811318(CHEK2)

NVS:	122903292(CHEK2)

ORO:	101386368(CHEK2)

EJU:	114225227(CHEK2)

ZCA:	113912998(CHEK2)

MLX:	118018616(CHEK2)

NSU:	110592495(CHEK2)

LWW:	102740114(CHEK2)

FCA:	101085665(CHEK2)

PYU:	121022574(CHEK2)

PCOO:

112870152(CHEK2)

PBG:	122470428(CHEK2)

PVIV:

125149108(CHEK2)

LRUF:

124518366

PTG:	102960814(CHEK2)

PPAD:

109253543(CHEK2)

PUC:

125914493

AJU:

106985461

HHV:	120227007(CHEK2)

BTA:	518897(CHEK2)

BOM:	102283552(CHEK2)

BIU:	109571019(CHEK2)

BBUB:

102409445(CHEK2)

BBIS:

104980115(CHEK2)

CHX:	102184180(CHEK2)

OAS:	101105532(CHEK2)

BTAX:

128062388(CHEK2) 128071171

ODA:	120871465(CHEK2)

CCAD:

122421545(CHEK2)

MBEZ:

129542403(CHEK2)

SSC:	100192447(CHEK2)

CFR:	102508820(CHEK2)

CBAI:

105066046(CHEK2)

CDK:	105099476(CHEK2)

VPC:	102528805(CHEK2)

BACU:

103014798(CHEK2)

BMUS:

118906782(CHEK2)

LVE:	103076926(CHEK2)

OOR:	101289528(CHEK2)

DLE:	111162720(CHEK2)

PCAD:

102986126(CHEK2)

PSIU:

116739234(CHEK2)

NASI:

112415141(CHEK2)

ECB:	100059288(CHEK2)

EPZ:	103554111(CHEK2)

EAI:	106827624(CHEK2)

MYB:	102250232(CHEK2)

MYD:	102766522(CHEK2)

MMYO:

118678212(CHEK2)

MLF:	111828035(CHEK2)

MDT:	132221612(CHEK2)

PKL:	118725344(CHEK2)

EFUS:

103287141(CHEK2)

MNA:	107526210(CHEK2)

DRO:	112310842(CHEK2)

SHON:

118991250(CHEK2)

AJM:	119055166(CHEK2)

PDIC:

114509918(CHEK2)

PHAS:

123810780(CHEK2)

MMF:	118639835(CHEK2)

PPAM:

129087453(CHEK2)

HAI:	109383036(CHEK2)

RFQ:	117017741(CHEK2)

PALE:

102882358(CHEK2)

PGIG:

120601945(CHEK2)

PVP:	105300942(CHEK2)

RAY:	107520494(CHEK2)

MJV:	108408453(CHEK2)

TOD:	119244807(CHEK2)

SARA:

101551593(CHEK2)

SETR:

126030601(CHEK2)

LAV:	100666208(CHEK2)

TMU:

101359759

ETF:	101654360(CHEK2)

DNM:	101433313(CHEK2)

MDO:	100030584(CHEK2)

GAS:	123256922(CHEK2)

SHR:	100932330(CHEK2)

AFZ:

127545635

PCW:	110215254(CHEK2)

TVP:	118833548(CHEK2)

OAA:	100077482(CHEK2)

GGA:	768913(CHEK2)

PCOC:

116228512(CHEK2)

MGP:	100543068(CHEK2)

CJO:	107321227(CHEK2)

TPAI:

128083884(CHEK2)

LMUT:

125701808(CHEK2)

NMEL:

110406189(CHEK2)

APLA:

119718547(CHEK2)

ACYG:

106043894(CHEK2)

CATA:

118257551(CHEK2)

AFUL:

116496237(CHEK2)

TGU:	100228558(CHEK2)

LSR:	110478117(CHEK2)

SCAN:

103818108(CHEK2)

PMOA:

120509791(CHEK2)

OTC:	121338890(CHEK2)

PRUF:

121364905(CHEK2)

GFR:	102038788(CHEK2)

FAB:	101811158(CHEK2)

OMA:	130259820(CHEK2)

PHI:	102110514(CHEK2)

PMAJ:

107211857(CHEK2)

CCAE:

111936476(CHEK2)

CCW:	104688640(CHEK2)

CBRC:

103615960(CHEK2)

ETL:	114061540(CHEK2)

ZAB:	102074783(CHEK2)

ZLE:	135454556(CHEK2)

ACHL:

103807248(CHEK2)

SVG:	106852403(CHEK2)

MMEA:

130579619(CHEK2)

HRT:	120760510(CHEK2)

SATI:

136368967(CHEK2)

FPG:	101911493(CHEK2)

FCH:	102057640(CHEK2)

CCRI:

104155061(CHEK2)

NNT:	104400160(CHEK2)

SHAB:

115614786(CHEK2)

ACUN:

113486115(CHEK2)

TALA:

104369204(CHEK2)

ACHC:

115346208(CHEK2)

HALD:

104310710(CHEK2)

HLE:	104840813(CHEK2)

AGEN:

126040677

GCL:

127022946

CSTI:

104550158(CHEK2)

LDI:	104339794(CHEK2)

MNB:	103778082(CHEK2)

DPUB:

104309009(CHEK2)

AVIT:

104273658(CHEK2)

BRHI:

104487976(CHEK2)

EGZ:	104122580(CHEK2)

NNI:	104015770(CHEK2)

PCRI:

104034884(CHEK2)

PCAO:

104040006(CHEK2)

PADL:

103922582(CHEK2)

AFOR:

103901854(CHEK2)

FGA:	104080965(CHEK2)

GSTE:

104250858(CHEK2)

CLV:	102090751(CHEK2)

MUI:	104533845(CHEK2)

PGUU:

104458250(CHEK2)

PLET:

104614156(CHEK2)

EHS:	104517007(CHEK2)

CMAC:

104476199(CHEK2)

CUCA:

104068451(CHEK2)

TEO:	104370071(CHEK2)

BREG:

104630198(CHEK2)

OHA:	104327946(CHEK2)

ACAR:

104520756(CHEK2)

CPEA:

104388023(CHEK2)

CVF:	104289437(CHEK2)

RTD:	128917243(CHEK2)

AAM:	106492744(CHEK2)

AROW:

112968877(CHEK2)

NPD:	112945202(CHEK2)

TGT:	104566530(CHEK2)

DNE:	112990117(CHEK2)

SCAM:

104142411(CHEK2)

ASN:	102386466(CHEK2)

AMJ:	102574431(CHEK2)

CPOO:

109312584(CHEK2)

GGN:	109290633(CHEK2)

PSS:	102461937(CHEK2)

CMY:	102947582(CHEK2)

CCAY:

125622921(CHEK2)

DCC:	119843583(CHEK2)

CPIC:

101952469(CHEK2)

TST:	117887954(CHEK2)

CABI:

116816357(CHEK2)

MRV:	120386116(CHEK2)

ASAO:

132780926(CHEK2)

PVT:	110083425(CHEK2)

PBI:	103066019(CHEK2)

PMUR:

107287280(CHEK2)

CTIG:

120316802(CHEK2)

TSR:	106550569(CHEK2)

PGUT:

117672313 132711948

APRI:

131185748(CHEK2)

PTEX:

113448613(CHEK2)

NSS:	113423945(CHEK2)

VKO:	123021468(CHEK2)

PMUA:

114587126(CHEK2)

PRAF:

128403965(CHEK2)

ZVI:	118076474(CHEK2)

HCG:	128338126(CHEK2)

GJA:	107123921(CHEK2)

STOW:

125442669(CHEK2)

EMC:	129341075(CHEK2)

XLA:	398179(chek2.L)

XTR:	100144952(chek2)

NPR:	108788045(CHEK2)

RTEM:

120937463(CHEK2)

BBUF:

120988812(CHEK2)

BGAR:

122924376(CHEK2)

MUO:	115479909(CHEK2)

GSH:	117365655(CHEK2)

DRE:	336998(chek2)

SRX:	107723314(chek2) 107751420

SANH:

107653214 107667648

SGH:	107550275 107567453

CCAR:

109047558 109050186

CAUA:

113067941 113072521

CGIB:

127957325 128014228

PTET:

122344848(chek2)

LROH:

127164710(chek2)

OMC:	131540908(chek2)

PPRM:

120469300(chek2)

RKG:	130088145(chek2)

MAMB:

125267298(chek2)

CIDE:

127513317

CERY:

137034452(chek2)

MASI:

127430321 127437788

TROS:

130550715(chek2)

TDW:	130419886(chek2)

MANU:

129439657(chek2)

IPU:

108255821

PHYP:

113525110(chek2)

SMEO:

124380672(chek2)

TFD:	113648162(chek2)

TVC:	132855263(chek2)

TRN:	134335354(chek2)

AMEX:

103034962(chek2)

CMAO:

118827351(chek2)

EEE:	113572926(chek2)

CHAR:

105890008(chek2)

TRU:	101063164(chek2)

TFS:	130525893(chek2)

TNG:	GSTEN00007555G001

TBEN:

117469109(chek2)

GACU:

117562423(chek2)

EMAC:

134873996(chek2)

ELY:	117252154(chek2)

EFO:	125890878(chek2)

PLEP:

121963614 121964737

SLUC:

116058675(chek2)

PFLV:

114555216(chek2)

PPUG:

119225341(chek2)

AFB:	129100893(chek2)

PSWI:

130196775(chek2)

MSAM:

119891558(chek2)

SCHU:

122876018(chek2)

CUD:	121509236(chek2)

ALAT:

119019026(chek2)

MZE:	101485707(chek2)

ONL:	100708289(chek2)

OAU:	116311592(chek2)

OLA:	101170645(chek2)

OML:	112137749(chek2)

CSAI:

133451182(chek2)

XMA:

102224037

XCO:

114154787

XHE:	116730244(chek2)

PRET:

103460387(chek2)

PFOR:

103156298(chek2)

PLAI:

106940749(chek2)

PMEI:

106910148(chek2)

GAF:	122828618(chek2)

PPRL:

129366189(chek2)

CVG:

107105136

CTUL:

119777639(chek2)

GMU:	124877950(chek2)

NFU:	107386179(chek2)

KMR:	108248076(chek2)

ALIM:

106536288(chek2)

NWH:	119412971(chek2)

AOCE:

111573057(chek2)

MCEP:

125012658(chek2)

CSEM:

103397943(chek2)

POV:

109645723

SSEN:

122769258(chek2)

HHIP:

117767744 117767746

HSP:	118114701(chek2)

PPLT:

128438819(chek2)

SMAU:

118314379(chek2)

LCF:

108894515

SDU:	111237444(chek2)

SLAL:

111649055(chek2)

XGL:	120787503(chek2)

HCQ:	109525295(chek2)

SSCV:

125993791

SBIA:

133499406(chek2)

PEE:	133399613(chek2)

PTAO:

133475665(chek2)

BPEC:

110169250(chek2)

MALB:

109957388

BSPL:

114861437(chek2)

SJO:	128364725(chek2)

SASA:

106580118 106585648

STRU:

115164873 115199789

OTW:	112248230 112263301(chek2)

OMY:	100286815(chek2) 110525341

OGO:	124034568 124036029(chek2)

ONE:	115111324 115139753

OKI:	109876183 109895648(chek2)

OKE:	118358049(chek2) 118392920

SALP:

111957639 111974924

SNH:	120053972 120063063

CCLU:

121550187 121584512

ELS:	105014423(chek2)

SFM:	108927301(chek2)

PKI:	111852734(chek2)

AANG:

118206841(chek2)

LOC:	102691768(chek2)

PSPA:

121299476(chek2)

ARUT:

117427120 117428486

PSEX:

120539988(chek2)

LCM:	102362683(CHEK2)

CMK:	103184008(chek2)

RTP:	109911275(chek2)

CPLA:

122562547(chek2)

HOC:	132827286(chek2)

LERI:

129709207(chek2)

PMRN:

116942575(CHEK2)

LRJ:

BFO:

BBEL:

CIN:

SCLV:

SPU:	115917991 589861

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG10895(lok)

DER:

6549116

DSE:

6614767

DSI:	Dsimw501_GD24241(Dsim_GD24241)

DYA:	Dyak_GE13292

DAN:

6497269

DSR:	110185643 110190216

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17408

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:	119639938 119640846

ECOE:

129942159

CLON:

129618600

HIS:

119653022

AGA:	1277641 1279197

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109407247 109414315 115258599

ASUA:

134212701

CQU:	CpipJ_CPIJ009147

CPII:

120428163

CNS:	116339187 116341340 116343718

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

122848931 122851129 122851130 122851131 122851146 122853374 122853380 122853485

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:	108903434 108903438

LDC:	111507285 111515892

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

692482(Chk2)

BMAN:

114252597

MSEX:

115456086

DPL:	KGM_211250

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

113381892 113385406 113385827 113390648

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

106678371(lok)

NLU:

111043225

HVI:	124367730 124367733

MQU:

128998475

PHU:	Phum_PHUM016570

FOC:	113202880 113211357 113217272

TPAL:

117644908 117646761 117647209

ZNE:	110837933 110840805

CSEC:

111862830 111875276

SGRE:

126326589

BROR:

134534368 134538038 134539591

IEL:

124158614

DPX:	DAPPUDRAFT_300413 DAPPUDRAFT_333806

DMK:

116919216

DPZ:	124313069 124342161

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

CSCU:

CVS:

LPOL:

PMEO:

CEL:	CELE_T08D2.7(chkr-1) CELE_Y60A3A.12(chk-2)

CBR:	CBG_20512(Cbr-chk-2) CBG_24469

CRQ:	GCK72_001426

NAI:	NECAME_12459

LGI:	LOTGIDRAFT_231530

PVUL:

126825193

PCAN:

112561834

BGT:

106067930

GAE:	121368989 121392397

HRF:

HRJ:

CRG:

CANU:

CVN:	111132497 111132498 111134476

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_171370

SHX:	MS3_00007174(CHEK2_2)

OVI:	T265_09218

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:	130641043 130655047

RES:

135684014

TAD:	TRIADDRAFT_29114

AQU:	100639331 100641313

SCE:	YDL101C(DUN1)

SEUB:

DI49_0969

SPAO:

SPAR_D01360

AGO:	AGOS_AFL188C

ERC:

Ecym_5624

KLA:	KLLA0_E01585g

KMX:	KLMA_20647(DUN1)

LTH:	KLTH0F09988g

VPO:	Kpol_1004p19

ZRO:	ZYRO0A07546g

CGR:	2890984(DUN1)

NCS:	NCAS_0B05910(NCAS0B05910)

NDI:	NDAI_0B03190(NDAI0B03190)

TPF:	TPHA_0C04570(TPHA0C04570)

TBL:	TBLA_0B07330(TBLA0B07330)

TGB:	HG536_0A02810

TDL:	TDEL_0G02820(TDEL0G02820)

KAF:	KAFR_0K02450(KAFR0K02450)

KNG:	KNAG_0A05670(KNAG0A05670)

ZMK:	HG535_0D01360

SLUD:

SCDLUD_002657

DHA:	DEHA2G21142g

PIC:	PICST_29649

PGU:	PGUG_02486

SPAA:

SPAPADRAFT_63052

LBG:	92210653(LODBEIA_P54570)

CAL:	CAALFM_C505100CA(DUN1)

CTP:	CTRG_06118

COT:	CORT_0B02820

CDU:	CD36_54700

CTEN:

18248705(DUN1)

CLU:	CLUG_01832

CLUS:

A9F13_21g00319

CAUR:

CJI96_0005360

PPA:	PAS_chr2-2_0040

PKZ:	C5L36_0C05680

BNN:	FOA43_002738

BBRX:

BRETT_002740

OPA:	HPODL_01729

NCR:	NCU02814(prd-4)

NTE:	NEUTE1DRAFT133979(NEUTE1DRAFT_133979)

SMP:	10809668(SMAC4_00634)

PAN:	PODANSg10057

PBEL:

QC761_107860(DUN1)

PPSD:

QC762_107860(DUN1)

PPSP:

QC763_107860(DUN1)

PPSA:

QC764_107860(DUN1)

TTT:	THITE_2121878

MTM:	MYCTH_2295050

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_2561

SSCK:

SPSK_05999

FGR:	FGSG_07121

FPU:	FPSE_04084

FPOA:

FPOAC1_010889

FVN:	FVRRES_11901

FVR:	FVEG_08045

FOX:	FOXG_01680

NHE:	NECHADRAFT_100063

FFC:	NCS54_00556100

FMU:	J7337_002900

TRE:	TRIREDRAFT_121061

TRR:	M419DRAFT_97168

TATV:

25775948(TrAtP1_004250)

TASP:

36607156(TrAFT101_003718)

MAW:	19245367(DUN1)

MAJ:

MAA_05678

MBRN:

26238758(G6M90_00g012080)

PCHM:

VFPPC_03045

CMT:

CCM_01421

AMUS:

LMH87_003650

PTKZ:

JDV02_001156(DUN1) JDV02_010336

VAL:	VDBG_04584

VDA:	VDAG_04135

CFJ:	CFIO01_10246

CHIG:

CH63R_00781

SAPO:

SAPIO_CDS3360

ELA:	UCREL1_4154

PFY:	PFICI_01812

SSL:	SS1G_04069

BFU:	BCIN_01g06480

MBE:

MBM_06218

PSCO:

LY89DRAFT_714214

GLZ:	GLAREA_11936

ANI:	ANIA_04279

AFM:	AFUA_7G03750

ACT:	ACLA_005430

NFI:	NFIA_024700

AOR:	AO090026000841

ANG:	An13g00100

ACHE:

ACHE_40251S

APUU:

APUU_60530S

PCS:	N7525_009307

PDP:	PDIP_01830

POU:	POX_h09603

TMF:	EYB26_005601

TRG:	TRUGW13939_09662

CIM:	CIMG_07470 CIMG_07520

CPW:	CPC735_044060 CPC735_044400

URE:	UREG_07803

ABE:

ARB_00949

TVE:

TRV_00735

PBL:	PAAG_00826

PBN:	PADG_04004

AJE:	HCAG_04049

BGH:	BDBG_01677

PNO:	SNOG_03701(SNOG_03700)

PTE:

PTT_12246

PTRR:

6346977(PtrM4_031470)

BZE:	COCCADRAFT_37277

BSC:	COCSADRAFT_38641

BOR:	COCMIDRAFT_37644

AALT:

CC77DRAFT_1019960

ARAB:

EKO05_0008103

ZTR:	MYCGRDRAFT_74088

PFJ:	MYCFIDRAFT_216120

FFU:	CLAFUR5_05096

CBET:

CB0940_11249

BCOM:

BAUCODRAFT_318019

NPA:	UCRNP2_2682

TML:	GSTUM_00011944001

CPUT:

CONPUDRAFT_75397

PTRC:

PtA15_17A256

PSTR:

Pst134EA_029073 Pst134EA_030501

RIE:	OCT59_020768

MBR:	MONBRDRAFT_15828(Cds1)

SRE:	PTSG_08777

DDI:	DDB_G0281567(fhkC)

DPP:	DICPUDRAFT_157188 DICPUDRAFT_29047 DICPUDRAFT_38535

DFA:	DFA_05550(fhkA)

EHI:	EHI_011510(90.t00001)

EDI:	EDI_074140

EIV:	EIN_018330 EIN_023820 EIN_059440 EIN_084960 EIN_186790 EIN_359640 EIN_397070 EIN_410720

TPS:	THAPSDRAFT_33182

GTT:	GUITHDRAFT_133907

» show all

Reference

PMID:18644861

Authors

Lovly CM, Yan L, Ryan CE, Takada S, Piwnica-Worms H

Title

Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379.

Journal

Mol Cell Biol 28:5874-85 (2008)
DOI:10.1128/MCB.00821-08

Sequence

[hsa:11200]

Reference

PMID:18317453

Authors

Bahassi EM, Ovesen JL, Riesenberg AL, Bernstein WZ, Hasty PE, Stambrook PJ

Title

The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage.

Journal

Oncogene 27:3977-85 (2008)
DOI:10.1038/onc.2008.17

Sequence

[hsa:11200]

Reference

PMID:9836640

Authors

Matsuoka S, Huang M, Elledge SJ

Title

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.

Journal

Science 282:1893-7 (1998)
DOI:10.1126/science.282.5395.1893

Sequence

[hsa:11200]

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