KEGG   ORTHOLOGY: K07193
Entry
K07193                      KO                                     

Name
SH2B, APS
Definition
SH2B adapter protein 2
Pathway
ko04722  Neurotrophin signaling pathway
ko04910  Insulin signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07193  SH2B, APS; SH2B adapter protein 2
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K07193  SH2B, APS; SH2B adapter protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K07193  SH2B, APS; SH2B adapter protein 2
Domain-containing proteins not elsewhere classified [BR:ko04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   K07193  SH2B, APS; SH2B adapter protein 2
Other DBs
GO: 0005070 0005068
Genes
HSA: 10603(SH2B2)
PTR: 100612162 107971854 112207775 112209794(SH2B2) 741557(SH2B2) 747832
GGO: 101129445(SH2B2) 115935381
PON: 100443516(SH2B2)
NLE: 100598632(SH2B2)
MCC: 714861(SH2B2)
MCF: 102121730(SH2B2)
CSAB: 103246680(SH2B2)
RRO: 104681196(SH2B2)
RBB: 108518901(SH2B2)
CJC: 100388274(SH2B2)
SBQ: 101032970
MMU: 23921(Sh2b2)
MCAL: 110294826(Sh2b2)
MPAH: 110312818(Sh2b2)
RNO: 114203(Sh2b2)
MUN: 110557240(Sh2b2)
CGE: 100767263(Sh2b2)
NGI: 103733485(Sh2b2)
HGL: 101724022(Sh2b2)
CCAN: 109681591(Sh2b2)
OCU: 100358497(SH2B2)
TUP: 102470319(SH2B2)
CFA: 489820(SH2B2)
VVP: 112935733(SH2B2)
AML: 105240494(SH2B2)
UMR: 103670203(SH2B2)
UAH: 113267828(SH2B2)
ORO: 101380881(SH2B2)
ELK: 111145688
FCA: 101090410(SH2B2)
PTG: 102949441(SH2B2)
PPAD: 109250551(SH2B2)
AJU: 106980692(SH2B2)
BTA: 617840(SH2B2)
BOM: 102271339(SH2B2)
BIU: 109578305(SH2B2)
BBUB: 102414008(SH2B2)
CHX: 102185424(SH2B2)
OAS: 101117815(SH2B2)
SSC: 100519708(SH2B2)
CFR: 102520752(SH2B2)
CDK: 105092381(SH2B2)
BACU: 103016923(SH2B2)
LVE: 103088787(SH2B2)
OOR: 101270777(SH2B2)
DLE: 111182007(SH2B2)
PCAD: 102992188(SH2B2)
ECB: 100059630
EPZ: 103551716(SH2B2)
EAI: 106839337(SH2B2)
MYB: 102251356(SH2B2)
MYD: 102754109(SH2B2)
MNA: 107526551(SH2B2)
HAI: 109385028(SH2B2)
DRO: 112314753(SH2B2)
PALE: 102898524(SH2B2)
RAY: 107511783(SH2B2)
MJV: 108389845(SH2B2)
LAV: 100670637(SH2B2)
TMU: 101348710
MDO: 100618553(SH2B2)
SHR: 100929846(SH2B2)
PCW: 110221267(SH2B2)
OAA: 100090126(SH2B2)
GGA: 771172(SH2B2)
MGP: 100543269(SH2B2)
CJO: 107322455(SH2B2)
NMEL: 110407624(SH2B2)
APLA: 101794843(SH2B2)
ACYG: 106041497(SH2B2)
TGU: 101232958(SH2B2)
LSR: 110482032(SH2B2)
SCAN: 103820253(SH2B2)
GFR: 102044475(SH2B2)
FAB: 101809934(SH2B2)
PHI: 102110271(SH2B2)
PMAJ: 107213014(SH2B2)
CCAE: 111937693(SH2B2)
CCW: 104691112(SH2B2)
ETL: 114056702(SH2B2)
FPG: 101923247(SH2B2)
FCH: 102058092(SH2B2)
CLV: 102087394(SH2B2)
EGZ: 104131790(SH2B2)
NNI: 104016105(SH2B2)
ACUN: 113487045(SH2B2)
PADL: 103912918(SH2B2)
AAM: 106497334(SH2B2)
ASN: 102369800(SH2B2)
AMJ: 102573426(SH2B2)
PSS: 102457660(SH2B2)
CMY: 102947329
CPIC: 101952717(SH2B2)
ACS: 103281085(sh2b2)
PVT: 110085138(SH2B2)
PBI: 103066811(SH2B2)
PMUR: 107298583(SH2B2)
TSR: 106556257(SH2B2)
PMUA: 114585341(SH2B2)
GJA: 107107679(SH2B2)
XLA: 108708031(sh2b2.L) 108709343(sh2b2.S)
XTR: 100488327(sh2b2)
NPR: 108801794(SH2B2)
DRE: 100535524(sh2b2)
SRX: 107720403(sh2b2) 107750119
IPU: 108280786(sh2b2)
PHYP: 113543006(sh2b2)
AMEX: 103023327(sh2b2)
EEE: 113583021(sh2b2)
TRU: 101065075(sh2b2)
LCO: 104924728(sh2b2)
NCC: 104959775(sh2b2)
MZE: 101487223(sh2b2)
ONL: 100707313(sh2b2)
OLA: 101159212(sh2b2)
XMA: 102238410(sh2b2)
XCO: 114133174(sh2b2)
PRET: 103474674(sh2b2)
CVG: 107081929(sh2b2)
NFU: 107380250(sh2b2)
KMR: 108240837(sh2b2)
ALIM: 106519398(sh2b2)
AOCE: 111575972(sh2b2)
CSEM: 103378466(sh2b2)
POV: 109647225
LCF: 108900851(sh2b2)
SDU: 111238129(sh2b2)
SLAL: 111654118
HCQ: 109526335
BPEC: 110163693(sh2b2)
MALB: 109974360(sh2b2)
ELS: 105005599(sh2b2) 105011112
LCM: 102363625(SH2B2)
CMK: 103188435(sh2b2)
RTP: 109913345 109915327(sh2b2)
CIN: 100179111
AAG: 5564176
AME: 552012
BIM: 100750156
BTER: 100649645
CCAL: 108623043
OBB: 114870892
SOC: 105196716
MPHA: 105829507
AEC: 105145418
ACEP: 105618172
VEM: 105566700
HST: 105187796
DQU: 106747411
CFO: 105255999
LHU: 105672917
PGC: 109864049
OBO: 105282573
PCF: 106791850
NVI: 100122053
CSOL: 105362487
MDL: 103578857
TCA: 661724
ATD: 109602601
NVL: 108568538
PRAP: 110991457
HAW: 110370766
TNL: 113502802
AGS: 114126632
BTAB: 109031472
CLEC: 106663614
ZNE: 110839402
TUT: 107362666
CSCU: 111618220
PTEP: 107445434
BMY: Bm1_41520
 » show all
Reference
PMID:9856458
  Authors
Qian X, Riccio A, Zhang Y, Ginty DD
  Title
Identification and characterization of novel substrates of Trk receptors in developing neurons.
  Journal
Neuron 21:1017-29 (1998)
DOI:10.1016/s0896-6273(00)80620-0
  Sequence
[rno:114203]
Reference
PMID:9989826
  Authors
Yokouchi M, Wakioka T, Sakamoto H, Yasukawa H, Ohtsuka S, Sasaki A, Ohtsubo M, Valius M, Inoue A, Komiya S, Yoshimura A
  Title
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.
  Journal
Oncogene 18:759-67 (1999)
DOI:10.1038/sj.onc.1202326

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