KEGG   ORTHOLOGY: K07209
Entry
K07209                      KO                                     
Symbol
IKBKB, IKKB
Name
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
Pathway
map01523  Antifolate resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04062  Chemokine signaling pathway
map04064  NF-kappa B signaling pathway
map04068  FoxO signaling pathway
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map04624  Toll and Imd signaling pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04722  Neurotrophin signaling pathway
map04910  Insulin signaling pathway
map04920  Adipocytokine signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05135  Yersinia infection
map05142  Chagas disease
map05145  Toxoplasmosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05206  MicroRNAs in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05212  Pancreatic cancer
map05215  Prostate cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00093  Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04014 Ras signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04064 NF-kappa B signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04668 TNF signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04068 FoxO signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04151 PI3K-Akt signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04150 mTOR signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04624 Toll and Imd signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04621 NOD-like receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04622 RIG-I-like receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04623 Cytosolic DNA-sensing pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04625 C-type lectin receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04660 T cell receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04658 Th1 and Th2 cell differentiation
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04659 Th17 cell differentiation
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04657 IL-17 signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04662 B cell receptor signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04062 Chemokine signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04920 Adipocytokine signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05206 MicroRNAs in cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05208 Chemical carcinogenesis - reactive oxygen species
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05221 Acute myeloid leukemia
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05220 Chronic myeloid leukemia
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05215 Prostate cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05222 Small cell lung cancer
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05170 Human immunodeficiency virus 1 infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05161 Hepatitis B
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05160 Hepatitis C
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05171 Coronavirus disease - COVID-19
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05164 Influenza A
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05162 Measles
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05168 Herpes simplex virus 1 infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05163 Human cytomegalovirus infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05169 Epstein-Barr virus infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05165 Human papillomavirus infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05130 Pathogenic Escherichia coli infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05132 Salmonella infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05131 Shigellosis
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05135 Yersinia infection
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05142 Chagas disease
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   05418 Fluid shear stress and atherosclerosis
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04936 Alcoholic liver disease
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04932 Non-alcoholic fatty liver disease
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
   04931 Insulin resistance
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta
Other DBs
GO: 0008384
Genes
HSA: 3551(IKBKB)
PTR: 472749(IKBKB)
PPS: 100989390(IKBKB)
GGO: 101141659(IKBKB)
PON: 100440586(IKBKB)
PPYG: 129043119(IKBKB)
NLE: 100588081(IKBKB)
HMH: 116461632(IKBKB)
SSYN: 129491548(IKBKB)
MCC: 704683(IKBKB)
MCF: 102146604(IKBKB)
MTHB: 126960750
MNI: 105476527(IKBKB)
CSAB: 103215686(IKBKB)
CATY: 105595759(IKBKB)
PANU: 101016447(IKBKB)
TGE: 112629970(IKBKB)
MLEU: 105554929(IKBKB)
RRO: 104666046(IKBKB)
RBB: 108540719(IKBKB)
TFN: 117095630(IKBKB)
PTEH: 111544093(IKBKB)
CANG: 105525125(IKBKB)
CJC: 100393096(IKBKB)
SBQ: 101052971(IKBKB)
CIMI: 108316185(IKBKB)
ANAN: 105733545(IKBKB)
CSYR: 103256847(IKBKB)
MMUR: 105878144(IKBKB)
LCAT: 123626609(IKBKB)
PCOQ: 105819687(IKBKB)
OGA: 100946157(IKBKB)
MMU: 16150(Ikbkb)
MCAL: 110300158(Ikbkb)
MPAH: 110336182(Ikbkb)
RNO: 84351(Ikbkb)
MCOC: 116069014(Ikbkb)
ANU: 117721547(Ikbkb)
MUN: 110556613(Ikbkb)
CGE: 100750488(Ikbkb)
MAUA: 101834429(Ikbkb)
PROB: 127220313(Ikbkb)
PLEU: 114705738(Ikbkb)
MORG: 121462326(Ikbkb)
MFOT: 126504411
AAMP: 119812324(Ikbkb)
NGI: 103726621(Ikbkb)
HGL: 101711077(Ikbkb)
CPOC: 100724538(Ikbkb)
CCAN: 109696400(Ikbkb)
DORD: 105991714(Ikbkb)
DSP: 122107663(Ikbkb)
PLOP: 125339226(Ikbkb)
NCAR: 124983354
MMMA: 107159633(Ikbkb)
OCU: 100356401
OPI: 101517015(IKBKB)
TUP: 102467954(IKBKB)
GVR: 103589266(IKBKB)
CFA: 482839(IKBKB)
CLUD: 112656000(IKBKB)
VVP: 112916156(IKBKB)
VLG: 121489510(IKBKB)
NPO: 129515857(IKBKB)
AML: 100471679(IKBKB)
UMR: 103677059(IKBKB)
UAH: 113245546(IKBKB)
UAR: 123780295(IKBKB)
ELK: 111144397
LLV: 125094028
MPUF: 101686932(IKBKB)
MNP: 132006530(IKBKB)
MLK: 131820342(IKBKB)
NVS: 122889856(IKBKB)
ORO: 101375346(IKBKB)
EJU: 114224851(IKBKB)
ZCA: 113924180(IKBKB)
MLX: 118009921(IKBKB)
NSU: 110573165(IKBKB)
LWW: 102750184(IKBKB)
FCA: 100142682(IKBKB)
PYU: 121012848(IKBKB)
PCOO: 112858003(IKBKB)
PBG: 122472994(IKBKB)
PVIV: 125163712(IKBKB)
LRUF: 124521298
PTG: 102963734(IKBKB)
PPAD: 109262264(IKBKB)
PUC: 125923306
AJU: 106990012
HHV: 120233999(IKBKB)
BTA: 281854(IKBKB)
BOM: 102281443(IKBKB)
BIU: 109553353(IKBKB)
BBUB: 102398886(IKBKB)
BBIS: 104993223(IKBKB)
CHX: 102177406(IKBKB)
OAS: 780484(IKBKB)
BTAX: 128068238(IKBKB)
ODA: 120865846(IKBKB)
CCAD: 122432633(IKBKB)
MBEZ: 129549430(IKBKB)
SSC: 100101471(IKBKB)
CFR: 102508142(IKBKB)
CBAI: 105071245(IKBKB)
CDK: 105086448(IKBKB)
VPC: 102528824(IKBKB)
BACU: 103015119(IKBKB)
BMUS: 118887797(IKBKB)
LVE: 103088633(IKBKB)
OOR: 101285763(IKBKB)
DLE: 111173552(IKBKB)
PCAD: 102976706(IKBKB)
PSIU: 116746707(IKBKB)
NASI: 112413114(IKBKB)
ECB: 100050167(IKBKB)
EPZ: 103562903(IKBKB)
EAI: 106828957(IKBKB)
MYB: 102261405(IKBKB)
MYD: 102773824(IKBKB)
MMYO: 118650776(IKBKB)
MLF: 102417312(IKBKB)
MDT: 132228611(IKBKB)
PKL: 118728482(IKBKB)
EFUS: 103288179(IKBKB)
MNA: 107523913(IKBKB)
DRO: 112321547(IKBKB)
SHON: 118993207(IKBKB)
AJM: 119047140(IKBKB)
PDIC: 114508493(IKBKB)
PHAS: 123807522(IKBKB)
MMF: 118622317(IKBKB)
PPAM: 129064790(IKBKB)
HAI: 109386279(IKBKB)
RFQ: 117021384(IKBKB)
PALE: 102893261(IKBKB)
PGIG: 120595665(IKBKB)
PVP: 105301022(IKBKB)
RAY: 107501353(IKBKB)
MJV: 108399795(IKBKB)
TOD: 119257853(IKBKB)
SARA: 101540472(IKBKB)
SETR: 126006407(IKBKB)
LAV: 100657363(IKBKB)
TMU: 101351256
ETF: 101657011(IKBKB)
DNM: 101411204(IKBKB)
MDO: 100033031(IKBKB)
GAS: 123233417(IKBKB)
SHR: 100928932(IKBKB)
AFZ: 127548272
PCW: 110196387(IKBKB)
TVP: 118843636(IKBKB)
OAA: 100078925(IKBKB)
GGA: 426792(IKBKB)
PCOC: 116234507(IKBKB)
MGP: 100542558(IKBKB)
CJO: 107323740(IKBKB)
TPAI: 128071868(IKBKB)
LMUT: 125685336(IKBKB)
NMEL: 110387184(IKBKB)
APLA: 101790255(IKBKB)
ACYG: 106044397(IKBKB)
CATA: 118256066(IKBKB)
AFUL: 116499350(IKBKB)
TGU: 100225072(IKBKB) 116807244
LSR: 110473406(IKBKB)
SCAN: 103822735(IKBKB)
PMOA: 120504880(IKBKB)
OTC: 121346776(IKBKB)
PRUF: 121359273(IKBKB)
GFR: 102035648(IKBKB)
FAB: 101809821(IKBKB)
OMA: 130261961(IKBKB)
PHI: 102100562(IKBKB)
PMAJ: 107213912(IKBKB)
CCAE: 111938770(IKBKB)
CCW: 104694916(IKBKB)
CBRC: 103615481(IKBKB)
ETL: 114066442(IKBKB)
ZAB: 102073615(IKBKB)
ZLE: 135456823(IKBKB)
ACHL: 103798520(IKBKB)
SVG: 106862058(IKBKB)
MMEA: 130584481(IKBKB)
HRT: 120764068(IKBKB)
SATI: 136372638(IKBKB)
FPG: 101922064(IKBKB)
FCH: 102058892(IKBKB)
CCRI: 104155069(IKBKB)
NNT: 104399565(IKBKB)
SHAB: 115618527(IKBKB)
ACUN: 113488090(IKBKB)
TALA: 104360558(IKBKB)
ACHC: 115350500(IKBKB)
HALD: 104315998(IKBKB)
HLE: 104828788(IKBKB)
AGEN: 126051568
GCL: 127025388
CSTI: 104549271(IKBKB)
LDI: 104340350(IKBKB)
MNB: 103775251(IKBKB)
DPUB: 104301261(IKBKB)
AVIT: 104274892(IKBKB)
BRHI: 104487936(IKBKB)
EGZ: 104135306(IKBKB)
NNI: 104016028(IKBKB)
PCRI: 104024544(IKBKB)
PCAO: 104039708(IKBKB)
PADL: 103920554(IKBKB)
AFOR: 103901011(IKBKB)
FGA: 104069132
GSTE: 104250915(IKBKB)
CLV: 102087238(IKBKB)
MUI: 104533819(IKBKB)
PGUU: 104458456(IKBKB)
PLET: 104614493(IKBKB)
EHS: 104514410(IKBKB)
CMAC: 104484702(IKBKB)
CUCA: 104068591(IKBKB)
TEO: 104374606(IKBKB)
BREG: 104630091(IKBKB)
OHA: 104333228(IKBKB)
ACAR: 104518147(IKBKB)
CPEA: 104384891(IKBKB)
CVF: 104285155(IKBKB)
RTD: 128919567(IKBKB)
AAM: 106487776(IKBKB)
AROW: 112974186(IKBKB)
NPD: 112953853(IKBKB)
TGT: 104566044(IKBKB)
DNE: 112990458(IKBKB)
SCAM: 104148759(IKBKB)
ASN: 102377560(IKBKB)
AMJ: 102561936(IKBKB)
CPOO: 109317391(IKBKB)
PSS: 102454676(IKBKB)
CMY: 102932073(IKBKB)
CCAY: 125626298(IKBKB)
DCC: 119848740(IKBKB)
CPIC: 101945515(IKBKB)
TST: 117873054(IKBKB)
CABI: 116819035(IKBKB)
MRV: 120397038(IKBKB)
ACS: 100551699(ikbkb)
ASAO: 132782482(IKBKB)
PVT: 110072148(IKBKB)
SUND: 121933447(IKBKB)
PBI: 103052688(IKBKB)
PMUR: 107287960(IKBKB)
CTIG: 120318799(IKBKB)
TSR: 106550867
PGUT: 117676049(IKBKB)
APRI: 131203844(IKBKB)
PTEX: 113445889(IKBKB)
NSS: 113427675(IKBKB)
VKO: 123027007(IKBKB)
PMUA: 114602842(IKBKB)
PRAF: 128420119(IKBKB)
ZVI: 118085966(IKBKB)
HCG: 128333575(IKBKB)
GJA: 107107812(IKBKB)
STOW: 125441474(IKBKB)
EMC: 129342159(IKBKB)
XLA: 432200(ikbkb.L)
XTR: 448125(ikbkb)
NPR: 108791446(IKBKB)
RTEM: 120933164(IKBKB)
BBUF: 120986314(IKBKB)
BGAR: 122927292(IKBKB)
MUO: 115469431(IKBKB)
GSH: 117362659(IKBKB)
DRE: 563560(ikbkb)
SRX: 107722850 107754415
SANH: 107671012
SGH: 107559596(ikbkb)
CCAR: 109095150(ikbkb)
CAUA: 113052773 113106968
CGIB: 127963498 128019162
PTET: 122350917(ikbkb)
LROH: 127169911(ikbkb)
OMC: 131545292(ikbkb)
PPRM: 120489071(ikbkb)
MAMB: 125279685(ikbkb)
CIDE: 127517699
CERY: 137026791(ikbkb)
MASI: 127424113
TROS: 130567729(ikbkb)
TDW: 130439789(ikbkb)
MANU: 129414665(ikbkb)
IPU: 108265675
IFU: 128607709(ikbkb)
PHYP: 113533569(ikbkb)
SMEO: 124400022(ikbkb)
TFD: 113656040(ikbkb)
TVC: 132853312(ikbkb)
TRN: 134318101(ikbkb)
AMEX: 103040024(ikbkb)
CMAO: 118813511(ikbkb)
EEE: 113584916(ikbkb)
CHAR: 105898455(ikbkb)
TRU: 101062431(ikbkb)
TFS: 130526093(ikbkb)
TNG: GSTEN00029571G001
LCO: 104921662(ikbkb)
NCC: 104956687(ikbkb)
TBEN: 117472510(ikbkb)
CGOB: 115013798(ikbkb)
PGEO: 117452298(ikbkb)
GACU: 117560475(ikbkb)
EMAC: 134873220(ikbkb)
ELY: 117252591(ikbkb)
EFO: 125889921(ikbkb)
PLEP: 121944151(ikbkb)
SLUC: 116054000(ikbkb)
ECRA: 117945478(ikbkb)
ESP: 116688937(ikbkb)
PFLV: 114555052(ikbkb)
GAT: 120830767(ikbkb)
PPUG: 119224939(ikbkb)
AFB: 129101396(ikbkb)
CLUM: 117736821(ikbkb)
PSWI: 130196210(ikbkb)
MSAM: 119891193(ikbkb)
SCHU: 122875692(ikbkb)
CUD: 121510304(ikbkb)
ALAT: 119019038(ikbkb)
MZE: 101472803(ikbkb)
ONL: 100698072(ikbkb)
OAU: 116311015(ikbkb)
OLA: 101170684(ikbkb)
OML: 112148770(ikbkb)
CSAI: 133450689(ikbkb)
XMA: 102223773(ikbkb)
XCO: 114154613(ikbkb)
XHE: 116729844(ikbkb)
PRET: 103470025(ikbkb)
PFOR: 103145827(ikbkb)
PLAI: 106956804(ikbkb)
PMEI: 106921755(ikbkb)
GAF: 122826476(ikbkb)
PPRL: 129365887(ikbkb)
CVG: 107089660(ikbkb)
CTUL: 119778144(ikbkb)
GMU: 124877211(ikbkb)
NFU: 107394259(ikbkb)
KMR: 108233707(ikbkb)
ALIM: 106536414(ikbkb)
NWH: 119413028(ikbkb)
AOCE: 111577292(ikbkb)
MCEP: 125011866(ikbkb)
CSEM: 103397763(ikbkb)
POV: 109637101(ikbkb)
SSEN: 122768945(ikbkb)
HHIP: 117767714(ikbkb)
HSP: 118114623(ikbkb)
PPLT: 128437788(ikbkb)
SMAU: 118313444(ikbkb)
LCF: 108881598
SDU: 111236497(ikbkb)
SLAL: 111665990(ikbkb)
XGL: 120805086(ikbkb)
HCQ: 109525796
SSCV: 125994011
SBIA: 133500035
PEE: 133399974(ikbkb)
PTAO: 133475135(ikbkb)
BPEC: 110155462(ikbkb)
MALB: 109956664(ikbkb)
BSPL: 114861862(ikbkb)
SJO: 128364098(ikbkb)
SASA: 106580426(ikbkb)
STRU: 115200286(ikbkb)
OTW: 112263933(ikbkb)
OMY: 110536185(ikbkb)
OGO: 124036437(ikbkb)
ONE: 115140184(ikbkb)
OKI: 109896029
OKE: 118371603(ikbkb)
SALP: 111958214
SNH: 120039020(ikbkb)
CCLU: 121573284
ELS: 105014298(ikbkb)
SFM: 108920198(ikbkb)
PKI: 111854363(ikbkb)
AANG: 118206636(ikbkb)
LOC: 102690045(ikbkb)
PSPA: 121302294 121303214
ARUT: 117397678
PSEX: 120538805(ikbkb)
LCM: 102358966(IKBKB)
RTP: 109927975(ikbkb)
CPLA: 122543166(ikbkb)
HOC: 132836867(ikbkb)
LERI: 129713371(ikbkb)
PMRN: 116945032(IKBKB)
LRJ: 133341906(IKBKB)
BFO: 118411310
BBEL: 109478257
CIN: 778921
DME: Dmel_CG4201(IKKbeta)
DER: 6553147
DSE: 6606172
DSI: Dsimw501_GD20310(Dsim_ird5)
DYA: Dyak_GE26340(Dyak_ird5)
DAN: 6494177
DSR: 110191738
DPO: 4802889
DPE: 6594219
DMN: 108156166
DWI: 26529178
DGR: 6563402
DMO: Dmoj_GI10102
DAZ: 108621533
DNV: 108659762
DHE: 111604649
DVI: 6631291
CCAT: 101451363
BOD: 106620316
BDR: 105231613
AOQ: 129235956
TDA: 119678504
MDE: 101888056
SCAC: 106088471
LCQ: 111689869
LSQ: 119610078
GFS: 119639948
ECOE: 129939931
CLON: 129610885
AGA: 3291915
ACOZ: 120959579
AARA: 120902673
AMER: 121596765
ASTE: 118512528
AFUN: 125763915
AMOU: 128301461
AALI: 118468506
AAG: 5577620
AALB: 109419873 115271052
ASUA: 134212977
CQU: CpipJ_CPIJ015672
CPII: 120430182
CNS: 116338941
BCOO: 119081411
AME: 726760
ACER: 108004488
ALAB: 122717408
ADR: 102676057
AFLR: 100872382
BIM: 100744732
BBIF: 117210395
BVK: 117237830
BVAN: 117157967
BTER: 100642917
BAFF: 126918287
BPYO: 122577593
BPAS: 132907958
CCAL: 108632449
MGEN: 117222822
SOC: 105197895
MPHA: 105831917
AEC: 105147535
ACEP: 105623150
VEM: 105563455
HST: 105186757
DQU: 106748819
CFO: 105251219
FEX: 115243813
LHU: 105679052
PGC: 109861528
OBO: 105277074
PCF: 106785497
PFUC: 122513736
VVE: 124953363
NVI: 100116284
CGLO: 123265625
FAS: 105269079
DAM: 107039787
CCIN: 107267930
AROA: 105689539
TCA: 655324 658393(ikkb)
DPA: 109540103
SOY: 115884520
CSET: 123312891
LDC: 111508410
DVV: 126889951
NVL: 108569535
APLN: 108739858
PPYR: 116176703 116176759
OTU: 111417278
BMOR: 101747125
BMAN: 114244430
MSEX: 115450784
DPL: KGM_202564
BANY: 112055005
MJU: 123873007
VCD: 124535557
MCIX: 123660892
PMAC: 106711966
PPOT: 106101605
PXU: 106113861
PRAP: 111001847
LSIN: 126974263
AAGE: 121734780
HAW: 110372140
HZE: 124636379
TNL: 113503695
SLIU: 111356586
OFU: 114357143
ATRA: 106135757
GMW: 113512859
PXY: 105396222
PGW: 126373092
LGLY: 125235272
CCRN: 123299767
CLEC: 106666374
HHAL: 106681274(IKKbeta)
HVI: 124357717
PHU: Phum_PHUM605130
TPAL: 117643604
DPX: DAPPUDRAFT_317376
DMK: 116928976
HAZT: 108669188
EAF: 111706894
PPOI: 119093165
VDE: 111250664
VJA: 111262983
DPTE: 113792695
DFR: 124499075
CSCU: 111632902
CVS: 136987834(IKKbeta)
PTEP: 107440477
UDV: 129218460
OBI: 106868427
OSN: 115211871
NVE: 116618481
AMIL: 114963622
DGT: 114531073
XEN: 124452742
HSY: 130628744
 » show all
Reference
PMID:15084260
  Authors
Hu MC, Lee DF, Xia W, Golfman LS, Ou-Yang F, Yang JY, Zou Y, Bao S, Hanada N, Saso H, Kobayashi R, Hung MC
  Title
IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a.
  Journal
Cell 117:225-37 (2004)
DOI:10.1016/S0092-8674(04)00302-2
Reference
PMID:9346485
  Authors
Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV
  Title
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK.
  Journal
Science 278:866-9 (1997)
DOI:10.1126/science.278.5339.866
  Sequence
[hsa:3551]

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (120)   
   KEGG PATHWAY (120)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1050)   
   KEGG GENES (548)   
   KEGG MGENES (236)   
   RefGene (264)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (1179)   

Download RDF
KEGG   ORTHOLOGY: K04467
Entry
K04467                      KO                                     
Symbol
IKBKA, IKKA, CHUK
Name
inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
Pathway
map01523  Antifolate resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04062  Chemokine signaling pathway
map04064  NF-kappa B signaling pathway
map04068  FoxO signaling pathway
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04920  Adipocytokine signaling pathway
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05135  Yersinia infection
map05142  Chagas disease
map05145  Toxoplasmosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05212  Pancreatic cancer
map05215  Prostate cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00882  Cocoon syndrome
H01931  Lethal-type popliteal pterygium syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04014 Ras signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04064 NF-kappa B signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04668 TNF signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04068 FoxO signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04151 PI3K-Akt signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04150 mTOR signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04621 NOD-like receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04622 RIG-I-like receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04623 Cytosolic DNA-sensing pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04625 C-type lectin receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04660 T cell receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04658 Th1 and Th2 cell differentiation
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04659 Th17 cell differentiation
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04657 IL-17 signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04662 B cell receptor signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   04062 Chemokine signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05208 Chemical carcinogenesis - reactive oxygen species
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05221 Acute myeloid leukemia
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05220 Chronic myeloid leukemia
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05215 Prostate cancer
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05222 Small cell lung cancer
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05170 Human immunodeficiency virus 1 infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05161 Hepatitis B
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05160 Hepatitis C
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05171 Coronavirus disease - COVID-19
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05164 Influenza A
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05162 Measles
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05168 Herpes simplex virus 1 infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05163 Human cytomegalovirus infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05169 Epstein-Barr virus infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05165 Human papillomavirus infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05130 Pathogenic Escherichia coli infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05132 Salmonella infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05131 Shigellosis
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05135 Yersinia infection
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05142 Chagas disease
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
   05418 Fluid shear stress and atherosclerosis
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
Other DBs
GO: 0008384
Genes
HSA: 1147(CHUK)
PTR: 450673(CHUK)
PPS: 100995228(CHUK)
GGO: 101137405(CHUK)
PON: 100174735(CHUK)
PPYG: 129006790(CHUK)
NLE: 100596225(CHUK)
HMH: 116485121(CHUK)
SSYN: 129467595(CHUK)
MCC: 709511(CHUK)
MCF: 102115964(CHUK)
MTHB: 126963067
MNI: 105478402(CHUK)
CSAB: 103216382(CHUK)
CATY: 105581830(CHUK)
PANU: 100998877(CHUK)
TGE: 112632013(CHUK)
MLEU: 105537745(CHUK)
RRO: 104656469(CHUK)
RBB: 108535077(CHUK)
TFN: 117068535(CHUK)
PTEH: 111538794(CHUK)
CANG: 105507149(CHUK)
SBQ: 101044006(CHUK)
CIMI: 108306378(CHUK)
ANAN: 105708229(CHUK)
CSYR: 103263189(CHUK)
MMUR: 105867131 105873508(CHUK)
LCAT: 123650134(CHUK)
PCOQ: 105824261(CHUK)
OGA: 100949554(CHUK)
MMU: 12675(Chuk)
MCAL: 110285285(Chuk)
MPAH: 110334538(Chuk)
RNO: 309361(Chuk)
MCOC: 116103881(Chuk)
ANU: 117701914 117712831(Chuk)
MUN: 110544653 110552966(Chuk)
CGE: 100754432(Chuk)
MAUA: 101837015(Chuk)
PROB: 127233576(Chuk)
PLEU: 114706431(Chuk)
MORG: 121454691(Chuk)
MFOT: 126504083
AAMP: 119816335(Chuk)
NGI: 103743976(Chuk)
HGL: 101719306(Chuk)
CPOC: 100726357(Chuk)
CCAN: 109681514(Chuk)
DORD: 105986731(Chuk)
DSP: 122115917(Chuk)
PLOP: 125346167(Chuk)
NCAR: 124985256
MMMA: 107149793(Chuk)
OCU: 100355888
OPI: 101536073(CHUK)
TUP: 102501308(CHUK)
GVR: 103588798(CHUK)
CFA: 477796(CHUK)
CLUD: 112672189(CHUK)
VVP: 112914804(CHUK)
VLG: 121484113(CHUK)
NPO: 129493669(CHUK)
AML: 100464675(CHUK)
UMR: 103658916(CHUK)
UAH: 113251823(CHUK)
UAR: 123795860(CHUK)
ELK: 111144921
LLV: 125084339
MPUF: 101680658(CHUK)
MNP: 132016695(CHUK)
MLK: 131828549(CHUK)
NVS: 122901015(CHUK)
ORO: 101364103(CHUK)
EJU: 114205217(CHUK)
ZCA: 113923411(CHUK)
MLX: 118024839(CHUK)
NSU: 110589216(CHUK)
LWW: 102728853(CHUK)
FCA: 101095617(CHUK)
PYU: 121037105(CHUK)
PCOO: 112854253(CHUK)
PBG: 122493134(CHUK)
PVIV: 125147812(CHUK)
LRUF: 124507057
PTG: 102949289(CHUK)
PPAD: 109272766(CHUK)
PUC: 125932873
AJU: 106966935
HHV: 120243217(CHUK)
BTA: 281073(CHUK)
BOM: 102281886(CHUK)
BIU: 109553086(CHUK)
BBUB: 102399613(CHUK)
BBIS: 105002719(CHUK)
CHX: 102181262(CHUK)
OAS: 101111143(CHUK)
BTAX: 128067677(CHUK)
ODA: 120873530(CHUK)
CCAD: 122446045(CHUK)
MBEZ: 129555451(CHUK)
SSC: 100135662(CHUK)
CFR: 102503497(CHUK)
CBAI: 105081887(CHUK)
CDK: 105084316(CHUK)
VPC: 102534431(CHUK)
BACU: 103015414(CHUK)
BMUS: 118883002(CHUK)
LVE: 103085220(CHUK)
OOR: 101281072(CHUK)
DLE: 111172396(CHUK)
PCAD: 102977668(CHUK)
PSIU: 116741676(CHUK)
NASI: 112392983(CHUK)
ECB: 100070393(CHUK)
EPZ: 103567228(CHUK)
EAI: 106846705(CHUK)
MYB: 102261467(CHUK)
MYD: 102760888(CHUK)
MMYO: 118669852(CHUK)
MLF: 102425603(CHUK)
MDT: 132214229(CHUK)
PKL: 118719404(CHUK)
EFUS: 103288473(CHUK)
MNA: 107542599(CHUK)
DRO: 112300474(CHUK)
SHON: 118999523(CHUK)
AJM: 119064546(CHUK)
PDIC: 114496345(CHUK)
PHAS: 123828668(CHUK)
MMF: 118632312(CHUK)
PPAM: 129077110(CHUK)
HAI: 109379632(CHUK)
RFQ: 117036177(CHUK)
PALE: 102879469(CHUK)
PGIG: 120609204(CHUK)
PVP: 105304619(CHUK)
RAY: 107499756(CHUK)
MJV: 108409586(CHUK)
TOD: 119233588(CHUK)
SARA: 101538389(CHUK)
SETR: 126033816(CHUK)
LAV: 100664361(CHUK)
TMU: 101341290
ETF: 101649582(CHUK)
DNM: 101429772(CHUK)
MDO: 100027952(CHUK)
GAS: 123236476(CHUK)
SHR: 100913624(CHUK)
PCW: 110213919(CHUK)
TVP: 118828849(CHUK)
OAA: 100082351(CHUK)
GGA: 423669(CHUK)
PCOC: 116234780(CHUK)
MGP: 100542478(CHUK)
CJO: 107315625(CHUK)
TPAI: 128078052(CHUK)
LMUT: 125693118(CHUK)
NMEL: 110390496(CHUK)
APLA: 119717337(CHUK)
ACYG: 106030064(CHUK)
CATA: 118247527(CHUK)
AFUL: 116491240(CHUK)
TGU: 100221281(CHUK)
LSR: 110474031(CHUK)
SCAN: 103814234(CHUK)
PMOA: 120499710(CHUK)
OTC: 121336198(CHUK)
PRUF: 121358096(CHUK)
GFR: 102042264(CHUK)
FAB: 101812706(CHUK)
OMA: 130255162(CHUK)
PHI: 102107801(CHUK)
PMAJ: 107206726(CHUK)
CCW: 104695067(CHUK)
CBRC: 103615287(CHUK)
ETL: 114067570(CHUK)
ZAB: 102074629(CHUK)
ZLE: 135449409(CHUK)
ACHL: 103805825(CHUK)
SVG: 106856724(CHUK)
MMEA: 130582408
HRT: 120755651(CHUK)
SATI: 136364390(CHUK)
FCH: 102053491(CHUK)
CCRI: 104165202(CHUK)
NNT: 104406104(CHUK)
SHAB: 115609102(CHUK)
ACUN: 113481883(CHUK)
TALA: 104364060(CHUK)
ACHC: 115348471(CHUK)
HALD: 104315548(CHUK)
HLE: 104833467(CHUK)
AGEN: 126043236
GCL: 127017902
CSTI: 104549225(CHUK)
LDI: 104352921(CHUK)
MNB: 103769846(CHUK)
DPUB: 104302590(CHUK)
AVIT: 104267618(CHUK)
BRHI: 104488253(CHUK)
EGZ: 104125140(CHUK)
PCRI: 104039002(CHUK)
PCAO: 104041028(CHUK)
PADL: 103924297(CHUK)
AFOR: 103895497
FGA: 104069270(CHUK)
GSTE: 104260485(CHUK)
CLV: 102084658(CHUK)
MUI: 104546789(CHUK)
PGUU: 104457773(CHUK)
PLET: 104620793(CHUK)
EHS: 104507608(CHUK)
CMAC: 104482587(CHUK)
CUCA: 104060058(CHUK)
TEO: 104380199(CHUK)
BREG: 104642304(CHUK)
OHA: 104330387(CHUK)
CPEA: 104397776(CHUK)
CVF: 104283555(CHUK)
RTD: 128911744(CHUK)
AAM: 106495295(CHUK)
AROW: 112962239(CHUK) 112977217
NPD: 112948431(CHUK)
TGT: 104567814(CHUK)
DNE: 112981613
SCAM: 104149540(CHUK)
ASN: 102374729(CHUK)
AMJ: 106736873(CHUK)
CPOO: 109318435(CHUK)
GGN: 109293915(CHUK)
PSS: 102454064(CHUK)
CMY: 102932800(CHUK)
CCAY: 125640184(CHUK)
DCC: 119858630(CHUK)
CPIC: 101931080(CHUK)
TST: 117879818(CHUK)
CABI: 116834403(CHUK)
MRV: 120368653(CHUK)
ACS: 100565922(chuk)
ASAO: 132771394(CHUK)
PVT: 110087236(CHUK)
SUND: 121925441(CHUK)
PBI: 103061898(CHUK)
PMUR: 107291445(CHUK) 114923654
CTIG: 120309925(CHUK)
TSR: 106548462(CHUK)
PGUT: 117667309 132709271(CHUK)
APRI: 131199180(CHUK)
PTEX: 113449389(CHUK)
NSS: 113425188(CHUK)
VKO: 123018301(CHUK)
PMUA: 114596983(CHUK)
PRAF: 128413638(CHUK)
ZVI: 118096210(CHUK)
HCG: 128350445(CHUK)
GJA: 107117758(CHUK)
STOW: 125437877(CHUK)
EMC: 129332264(CHUK)
XLA: 444556(chuk.S)
XTR: 549654(chuk)
NPR: 108797654(CHUK)
RTEM: 120909050(CHUK)
BBUF: 121003342(CHUK)
BGAR: 122939970(CHUK)
MUO: 115470218(CHUK)
GSH: 117358706(CHUK)
DRE: 393287(chuk)
SRX: 107726965 107743510
SANH: 107655432(chuk) 107666359
SGH: 107559325 107601877
CCAR: 109092137 109100658(chuk)
CAUA: 113056969 113112701
CGIB: 127970460 128026207
PTET: 122356355(chuk)
LROH: 127175327(chuk)
OMC: 131552635(chuk)
PPRM: 120479686(chuk)
RKG: 130089640(chuk)
MAMB: 125276913(chuk)
CIDE: 127524669
CERY: 137020554(chuk)
MASI: 127412362 127413967
TROS: 130559223(chuk)
TDW: 130431939(chuk)
MANU: 129416144(chuk)
IPU: 108263650
IFU: 128605794(chuk)
PHYP: 113542836(chuk)
SMEO: 124396202(chuk)
TFD: 113636298(chuk)
TVC: 132847409(chuk)
TRN: 134314813(chuk)
AMEX: 103033415(chuk)
CMAO: 118810516 118810719
EEE: 113582078(chuk)
CHAR: 105902233 105903749(chuk)
TRU: 101068225 101069880
TFS: 130533672 130538131(chuk)
TNG: GSTEN00022283G001 GSTEN00030651G001
LCO: 104928982 104930409
NCC: 104960684 104961343
TBEN: 117473417 117499461
CGOB: 115019941 115024640
PGEO: 117459464 117465106
GACU: 117536794 117547053
EMAC: 134858473 134870895
ELY: 117247242 117247863
EFO: 125880386 125903733
PLEP: 121954423 121958640
SLUC: 116053123 116060936
ECRA: 117936511 117960217
ESP: 116670894 116705198
PFLV: 114548159 114571888
GAT: 120819606 120820624
PPUG: 119213096 119214000
AFB: 129091327 129092009
CLUM: 117744348 117748347
PSWI: 130203616 130207612
MSAM: 119915458 119917364
SCHU: 122868207 122884588
CUD: 121511183 121528381
ALAT: 119010013 119033964
MZE: 101486267 101487089
ONL: 100692869 100698148
OAU: 116321245 116322782
OLA: 101159621 101171857
OML: 112154264(chuk) 112162018
CSAI: 133419240 133463692
XMA: 102221657 102226088
XCO: 114138537 114151890
XHE: 116713354 116727210
PRET: 103476976 103481753
PFOR: 103134044 103152473
PLAI: 106944810 106960919
PMEI: 106915153 106915993
GAF: 122823466 122842298
PPRL: 129368162(chuk)
CVG: 107086576 107089566
CTUL: 119782488 119790655
GMU: 124858595 124875252
NFU: 107375593 107387313(chuk)
KMR: 108234021 108250658
ALIM: 106521989(chuk) 106533626
NWH: 119418051 119424196
AOCE: 111567460 111581409
MCEP: 125018358 125022650
CSEM: 103387400 103398848
POV: 109629542 109644018
SSEN: 122759323 122782266
HHIP: 117753178 117775975
HSP: 118100852 118118677
PPLT: 128427368 128453181
SMAU: 118283502 118287850
LCF: 108891107 108892003
SDU: 111220255 111234378
SLAL: 111655428 111658207
XGL: 120794257 120796054
HCQ: 109516272 109518553
SSCV: 125978312 125991640
SBIA: 133495343 133509979
PEE: 133410156 133417719
PTAO: 133469133 133485849
BPEC: 110154188 110157171
MALB: 109961044 109962729(kctd2)
BSPL: 114845361 114870842
SJO: 128372978 128381630
SASA: 106579286 106579422 106589264
STRU: 115158948 115162780 115201018
OTW: 112223622 112223895 112224128
OMY: 110491527 110491813 110499151
OGO: 124039858 124048289 124048544
ONE: 115106499 115106755 115143915
OKI: 109865430 109865571 109869960
OKE: 118357674 118363556 118366609
SALP: 111967645 111978057 111978258
SNH: 120029505 120046219 120046430
CCLU: 121542592 121547254 121568297
ELS: 105006906 105010696
SFM: 108933554(chuk)
PKI: 111836749(chuk)
AANG: 118220615(chuk)
LOC: 102691336(chuk)
PSPA: 121321809(chuk)
ARUT: 117416037(chuk)
PSEX: 120541713(chuk)
LCM: 102361819(CHUK)
CMK: 103181859(chuk)
RTP: 109918795(chuk)
CPLA: 122541851(chuk)
HOC: 132835109(chuk)
LERI: 129712925(chuk)
SCLV: 120347579
LPIC: 129282029
ARUN: 117304139
SKO: 100375591 102806810
BPYO: 122577651
FVI: 122529363
OBB: 114871896
OLG: 117608213
NMEA: 116434059
CGIG: 122402233
VPS: 122633754
VCRB: 124429125
CSOL: 105359082
MDL: 103578013
AGIF: 122856282
VCAN: 122409932
AGB: 108913950
NLU: 111048096
MQU: 128985549
FOC: 113214861
ZNE: 110838212
CSEC: 111866549
BROR: 134535947
IEL: 124160777
FCD: 110852083
PVM: 113819389
PJA: 122243754
PCHN: 125026384
HAME: 121859114
PCLA: 123766496
CQD: 128699630
PTRU: 123515125
MNZ: 135197696
LSM: 121126301
TCF: 131887932
DSV: 119436697
RSAN: 119396275
RMP: 119161269
ABRU: 129966871
SDM: 118199832
HRO: HELRODRAFT_191565
PVUL: 126811745
PCAN: 112557750
GAE: 121379525
HRF: 124132163
HRJ: 124286694
CRG: 105343370 105343371
CANU: 128165598 128165600
CVN: 111120947 111121090
OED: 125668035 125670715
MYI: 110456994
PMAX: 117328789
MCAF: 127707582
MMER: 123563603
RPHI: 132743570
DPOL: 127865919
MAEA: 128217320
LJP: 135467541
LAK: 106170753
LLON: 135494706
EPA: 110254140
ATEN: 116302916
HMG: 100207607
RES: 135681046
TAD: TRIADDRAFT_62259
 » show all
Reference
PMID:9244310
  Authors
Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M
  Title
Identification and characterization of an IkappaB kinase.
  Journal
Cell 90:373-83 (1997)
DOI:10.1016/S0092-8674(00)80344-X
  Sequence
[hsa:1147]
Reference
PMID:20501937
  Authors
Razani B, Zarnegar B, Ytterberg AJ, Shiba T, Dempsey PW, Ware CF, Loo JA, Cheng G
  Title
Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation.
  Journal
Sci Signal 3:ra41 (2010)
DOI:10.1126/scisignal.2000778

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (106)   
   KEGG PATHWAY (106)   
Disease (2)   
   KEGG DISEASE (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1029)   
   KEGG GENES (569)   
   KEGG MGENES (237)   
   RefGene (217)   
   OC (6)   
Literature (2)   
   PubMed (2)   
All databases (1144)   

Download RDF
KEGG   ORTHOLOGY: K07210
Entry
K07210                      KO                                     
Symbol
IKBKG, IKKG, NEMO
Name
inhibitor of nuclear factor kappa-B kinase subunit gamma
Pathway
map01523  Antifolate resistance
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04062  Chemokine signaling pathway
map04064  NF-kappa B signaling pathway
map04151  PI3K-Akt signaling pathway
map04210  Apoptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04623  Cytosolic DNA-sensing pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04668  TNF signaling pathway
map04920  Adipocytokine signaling pathway
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05135  Yersinia infection
map05142  Chagas disease
map05145  Toxoplasmosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05208  Chemical carcinogenesis - reactive oxygen species
map05212  Pancreatic cancer
map05215  Prostate cancer
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05340  Primary immunodeficiency
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00089  IFN-gamma/IL-12 axis
H00095  Ectodermal dysplasia and immunodeficiency
H00540  Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID)
H00645  Incontinentia pigmenti
H01245  Immunodeficiency without anhidrotic ectodermal dysplasia
H02621  X-linked systemic autoinflammatory disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04014 Ras signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04064 NF-kappa B signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04668 TNF signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04151 PI3K-Akt signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04621 NOD-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04622 RIG-I-like receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04623 Cytosolic DNA-sensing pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04625 C-type lectin receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04660 T cell receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04658 Th1 and Th2 cell differentiation
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04659 Th17 cell differentiation
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04657 IL-17 signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04662 B cell receptor signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   04062 Chemokine signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05208 Chemical carcinogenesis - reactive oxygen species
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05203 Viral carcinogenesis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05221 Acute myeloid leukemia
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05220 Chronic myeloid leukemia
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05215 Prostate cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05222 Small cell lung cancer
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05170 Human immunodeficiency virus 1 infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05161 Hepatitis B
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05160 Hepatitis C
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05171 Coronavirus disease - COVID-19
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05164 Influenza A
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05162 Measles
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05168 Herpes simplex virus 1 infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05163 Human cytomegalovirus infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05169 Epstein-Barr virus infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05165 Human papillomavirus infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05130 Pathogenic Escherichia coli infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05132 Salmonella infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05131 Shigellosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05135 Yersinia infection
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05142 Chagas disease
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09163 Immune disease
   05340 Primary immunodeficiency
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
   05418 Fluid shear stress and atherosclerosis
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
Protein kinases [BR:ko01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
Genes
HSA: 8517(IKBKG)
PTR: 100609537(IKBKG) 100610002
PPS: 100987483(IKBKG) 117977645
GGO: 101145841(IKBKG) 115932121
PON: 100449496(IKBKG)
PPYG: 129023798(IKBKG)
NLE: 100603768(IKBKG)
HMH: 116464818(IKBKG)
SSYN: 129476172(IKBKG)
MCC: 701237(IKBKG)
MCF: 102115368(IKBKG) 135964355
MTHB: 126945470
MNI: 105471007
CSAB: 103232832(IKBKG)
CATY: 105573773(IKBKG)
TGE: 112616513(IKBKG) 112616847
MLEU: 105534277(IKBKG)
RRO: 104667046(IKBKG)
RBB: 108518784(IKBKG)
TFN: 117078341(IKBKG)
CANG: 105527033(IKBKG)
CJC: 100390258(IKBKG)
SBQ: 101043425(IKBKG)
CIMI: 108298093(IKBKG)
ANAN: 105727270(IKBKG)
CSYR: 103255498(IKBKG)
MMUR: 105867816(IKBKG)
LCAT: 123628501(IKBKG)
PCOQ: 105824538(IKBKG)
OGA: 100958883(IKBKG)
MMU: 16151(Ikbkg)
MCAL: 110287188(Ikbkg)
MPAH: 110313464(Ikbkg)
RNO: 309295(Ikbkg)
MCOC: 116086280(Ikbkg)
ANU: 117695513(Ikbkg)
MUN: 110562528(Ikbkg)
CGE: 100759762(Ikbkg)
MAUA: 101824046(Ikbkg)
PROB: 127217362(Ikbkg)
PLEU: 114706175(Ikbkg)
MORG: 121437198 121440264
MFOT: 126490256
AAMP: 119804668(Ikbkg)
NGI: 103731232(Ikbkg)
HGL: 101712077(Ikbkg)
CPOC: 100722308(Ikbkg)
CCAN: 109691919(Ikbkg)
DORD: 106000155(Ikbkg)
DSP: 122097005(Ikbkg)
PLOP: 125343265(Ikbkg)
NCAR: 124971778
MMMA: 107160284(Ikbkg)
OCU: 100328905(IKBKG)
OPI: 101535976(IKBKG)
TUP: 102476758(IKBKG)
GVR: 103604367(IKBKG)
CLUD: 112668352(IKBKG)
VVP: 112911512(IKBKG)
VLG: 121482779(IKBKG)
NPO: 129517602(IKBKG)
AML: 100470223(IKBKG)
UMR: 103679680(IKBKG)
UAR: 123791737
ELK: 111139191
LLV: 125091312
MPUF: 101671648(IKBKG)
MNP: 132006829(IKBKG)
MLK: 131822182(IKBKG)
NVS: 122897563(IKBKG)
ORO: 101384959(IKBKG)
EJU: 114203804(IKBKG)
ZCA: 113930597 113930605(IKBKG) 118356554
MLX: 118014480(IKBKG)
NSU: 110574194(IKBKG)
LWW: 102742694(IKBKG)
FCA: 101086544(IKBKG)
PYU: 121025049(IKBKG)
PCOO: 112871176(IKBKG)
PBG: 122477442(IKBKG)
PVIV: 125159286(IKBKG)
LRUF: 124525847
PPAD: 109261148(IKBKG) 109261721
PUC: 125932096
AJU: 106988817
HHV: 120226622(IKBKG)
BTA: 281855(IKBKG)
BOM: 102287968(IKBKG)
BBUB: 102394706(IKBKG)
CHX: 102171591(IKBKG)
OAS: 101107332(IKBKG)
BTAX: 128069947(IKBKG)
ODA: 120881825(IKBKG)
CCAD: 122434540(IKBKG)
MBEZ: 129564146(IKBKG)
SSC: 100127355(IKBKG)
CFR: 102519782(IKBKG)
CBAI: 105076053(IKBKG) 105076396
CDK: 105106603(IKBKG)
VPC: 102541871(IKBKG)
BACU: 103017855
BMUS: 118889045(IKBKG)
LVE: 103074882(IKBKG)
OOR: 101272428(IKBKG)
DLE: 111170969(IKBKG)
PCAD: 102980964(IKBKG) 114485485
PSIU: 116747398(IKBKG)
NASI: 112400454(IKBKG)
ECB: 100058432(IKBKG)
EPZ: 103543979
EAI: 106828814(IKBKG)
MYB: 102252013(IKBKG)
MYD: 102772051(IKBKG)
MMYO: 118653690(IKBKG)
MLF: 102436137(IKBKG)
MDT: 132224109(IKBKG)
PKL: 118706407(IKBKG)
EFUS: 103302255(IKBKG)
MNA: 107544156(IKBKG)
DRO: 112296261(IKBKG)
SHON: 118994325(IKBKG)
AJM: 119053789(IKBKG)
PDIC: 114504586(IKBKG)
PHAS: 123823081(IKBKG)
MMF: 118635619(IKBKG)
PPAM: 129074378(IKBKG)
HAI: 109377344(IKBKG)
RFQ: 117020791(IKBKG)
PALE: 102880203(IKBKG)
PGIG: 120605919(IKBKG)
PVP: 105302532(IKBKG)
RAY: 107499585(IKBKG)
MJV: 108400819(IKBKG)
TOD: 119245781(IKBKG)
SARA: 101536840(IKBKG)
SETR: 125999080(IKBKG)
LAV: 100661492(IKBKG)
TMU: 101347574
ETF: 101648136(IKBKG)
DNM: 101439489(IKBKG)
MDO: 100022918(IKBKG)
GAS: 123253779(IKBKG)
SHR: 100926701(IKBKG)
AFZ: 127542289
PCW: 110200334(IKBKG)
TVP: 118833128(IKBKG)
OAA: 100073613(IKBKG)
TGU: 115491960(IKBKG)
PMOA: 120504128(IKBKG)
OTC: 121337229(IKBKG)
PRUF: 121357727(IKBKG)
FAB: 101821038
OMA: 130266109(IKBKG)
PHI: 102113899
PMAJ: 107198881(IKBKG)
CCAE: 111942179(IKBKG)
CCW: 120412233(IKBKG)
ZLE: 135461073(IKBKG)
SATI: 136374835
AGEN: 126035169
ASN: 102374662(IKBKG)
AMJ: 102561500(IKBKG)
PSS: 102445093(IKBKG)
CMY: 102938812(IKBKG)
CCAY: 125628486(IKBKG)
DCC: 119847100(IKBKG)
CPIC: 101942490(IKBKG)
CABI: 116823432(IKBKG)
MRV: 120388769(IKBKG)
ACS: 100567119(ikbkg)
ASAO: 132767870(IKBKG)
PVT: 110089205(IKBKG)
SUND: 121922695(IKBKG)
PBI: 103053675(IKBKG)
PMUR: 107284206(IKBKG)
CTIG: 120301305(IKBKG)
PGUT: 117675545(IKBKG)
APRI: 131191305(IKBKG)
PTEX: 113443435(IKBKG)
NSS: 113417663(IKBKG)
VKO: 123030004(IKBKG)
PMUA: 114588195(IKBKG)
PRAF: 128404911(IKBKG)
ZVI: 118078861(IKBKG)
HCG: 128345404(IKBKG)
GJA: 107114301
STOW: 125425434(IKBKG)
EMC: 129345981(IKBKG)
XLA: 735069(ikbkg.L)
XTR: 100145270(ikbkg)
NPR: 108791352(IKBKG)
RTEM: 120914229(IKBKG)
BBUF: 121009140(IKBKG)
BGAR: 122946400(IKBKG)
MUO: 115463580(IKBKG)
GSH: 117348290(IKBKG)
DRE: 541530(ikbkg)
SRX: 107737639 107741321
SANH: 107657029 107672044
SGH: 107560912 107562470
CCAR: 109088214 109088584
CAUA: 113069111 113094667
CGIB: 127945040 128012000
PTET: 122328953(ikbkg)
LROH: 127155107(ikbkg)
OMC: 131532646(ikbkg)
PPRM: 120463432(ikbkg)
RKG: 130081706(ikbkg)
MAMB: 125260117(ikbkg)
CIDE: 127505066
CERY: 137009531(ikbkg)
MASI: 127419435 127420114
TROS: 130545480(ikbkg)
TDW: 130409812(ikbkg)
MANU: 129430990(ikbkg)
IPU: 108275953
IFU: 128619519(ikbkg)
PHYP: 113530655(ikbkg)
SMEO: 124399204(ikbkg)
TFD: 113658245(ikbkg)
TVC: 132862050(ikbkg)
TRN: 134333573(ikbkg)
AMEX: 103043929(ikbkg)
CMAO: 118822022(ikbkg)
EEE: 113587986(ikbkg)
CHAR: 105894130(ikbkg)
TRU: 101069645
TFS: 130530458(ikbkg)
TNG: GSTEN00004906G001
LCO: 104933745(ikbkg)
TBEN: 117491093(ikbkg)
CGOB: 115010596(ikbkg)
PGEO: 117448867 117448869
GACU: 117541485(ikbkg)
EMAC: 134870957(ikbkg)
ELY: 117258475(ikbkg)
EFO: 125892420(ikbkg)
SLUC: 116040658(ikbkg)
ECRA: 117947160(ikbkg)
ESP: 116693209(ikbkg)
PFLV: 114558815(ikbkg)
GAT: 100174893(ikbkg)
PPUG: 119200280 119222208
AFB: 129100170(ikbkg)
CLUM: 117732959(ikbkg)
PSWI: 130199061(ikbkg)
MSAM: 119905773 119919380
SCHU: 122883045(ikbkg)
CUD: 121517148(ikbkg)
ALAT: 119022646(ikbkg)
MZE: 101466977(ikbkg)
ONL: 100703664(ikbkg)
OAU: 116325151(ikbkg)
OLA: 101162681(ikbkg)
OML: 112158682(ikbkg)
CSAI: 133456872(ikbkg)
XMA: 102233509(ikbkg)
XCO: 114140444(ikbkg)
XHE: 116724200(ikbkg)
PRET: 103466941(ikbkg)
PFOR: 103150228(ikbkg)
PLAI: 106955713(ikbkg)
PMEI: 106907785(ikbkg)
GAF: 122836700(ikbkg)
PPRL: 129371690(ikbkg)
CVG: 107093789
CTUL: 119775467(ikbkg)
GMU: 124876519(ikbkg)
NFU: 107391543(ikbkg)
KMR: 108249185(ikbkg)
ALIM: 106523021(ikbkg)
NWH: 119417767(ikbkg)
AOCE: 111582017
MCEP: 125022415(ikbkg)
CSEM: 103384713(ikbkg)
POV: 109630748(ikbkg)
SSEN: 122777508(ikbkg)
HHIP: 117765388(ikbkg)
HSP: 118110546(ikbkg)
PPLT: 128443156(ikbkg)
SMAU: 118316602(ikbkg)
LCF: 108899625
SDU: 111236982(ikbkg)
SLAL: 111659926(ikbkg)
XGL: 120803427(ikbkg)
HCQ: 109528595(ikbkg)
SSCV: 125987862
SBIA: 133512340(ikbkg)
PEE: 133408750(ikbkg)
PTAO: 133487166(ikbkg)
BPEC: 110162114(ikbkg)
MALB: 109969980
BSPL: 114858847(ikbkg)
SJO: 128357039(ikbkg)
SASA: 106572992 106590733(ikbkg) 106592447
STRU: 115165245(ikbkg) 115168741
OTW: 112221359(ikbkg) 112239880 121840490
OMY: 110492712(ikbkg) 110532862
OGO: 124032432(ikbkg) 124045443
OKI: 109881207(ikbkg) 109885021
OKE: 118376297 118379875
SALP: 112072968
SNH: 120039965 120061717(ikbkg)
CCLU: 121537221 121555481
ELS: 105030753(ikbkg)
SFM: 108918214 108939062
PKI: 111837508(ikbkg) 111855295
AANG: 118210597(ikbkg)
LOC: 102682818
PSPA: 121329109(ikbkg)
ARUT: 117401606 117404249 117962689
PSEX: 120543156(ikbkg)
LCM: 102351908(IKBKG)
HOC: 132809022(ikbkg)
PMRN: 116952348
LRJ: 133355480
ABRU: 129964194
 » show all
Reference
PMID:9751060
  Authors
Rothwarf DM, Zandi E, Natoli G, Karin M
  Title
IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex.
  Journal
Nature 395:297-300 (1998)
DOI:10.1038/26261
  Sequence
[hsa:8517]
Reference
PMID:14695475
  Authors
Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M, Xiao W, Dixit VM
  Title
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
  Journal
Nature 427:167-71 (2004)
DOI:10.1038/nature02273

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (106)   
   KEGG PATHWAY (106)   
Disease (6)   
   KEGG DISEASE (6)   
Gene (534)   
   KEGG GENES (353)   
   KEGG MGENES (83)   
   RefGene (96)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (650)   

Download RDF
DBGET integrated database retrieval system