KEGG   ORTHOLOGY: K07360
Entry
K07360                      KO                                     

Name
ZAP70
Definition
tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
Pathway
ko04014  Ras signaling pathway
ko04064  NF-kappa B signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko04660  T cell receptor signaling pathway
ko05135  Yersinia infection
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05340  Primary immunodeficiency
Disease
H00093  Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
   04064 NF-kappa B signaling pathway
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
   04660 T cell receptor signaling pathway
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
   04658 Th1 and Th2 cell differentiation
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
   04659 Th17 cell differentiation
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
  09163 Immune disease
   05340 Primary immunodeficiency
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07360  ZAP70; tyrosine-protein kinase ZAP-70
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K07360  ZAP70; tyrosine-protein kinase ZAP-70
Protein kinases [BR:ko01001]
 Non-receptor tyrosine kinases
  SYK family
   K07360  ZAP70; tyrosine-protein kinase ZAP-70
Other DBs
GO: 0004715
Genes
HSA: 7535(ZAP70)
PTR: 459427(ZAP70)
PPS: 100971372(ZAP70)
GGO: 101139136
PON: 100451782
NLE: 100589243
MCC: 707555
MCF: 102135442(ZAP70)
CSAB: 103241092(ZAP70)
RRO: 104661474
RBB: 108529480
CJC: 100390922(ZAP70)
SBQ: 101036932(ZAP70)
MMU: 22637(Zap70)
MCAL: 110297598
MPAH: 110321893
RNO: 301348(Zap70)
MUN: 110545437
CGE: 100767740
NGI: 103738088(Zap70)
HGL: 101716577(Zap70)
CCAN: 109695320
OCU: 100342021(ZAP70)
TUP: 102469719(ZAP70)
CFA: 100271860(ZAP70)
VVP: 112915328
AML: 100473238
UMR: 103671189(ZAP70)
UAH: 113246717
ORO: 101377393(ZAP70)
ELK: 111155922
FCA: 101097059
PTG: 102969244(ZAP70)
PPAD: 109273394
AJU: 106976677
BTA: 504509(ZAP70)
BOM: 102287403(ZAP70)
BIU: 109565800
BBUB: 102408544
CHX: 102176695(ZAP70)
OAS: 101112639
SSC: 100739325
CFR: 102509559
CDK: 105099801
BACU: 103014268(ZAP70)
LVE: 103074297(ZAP70)
OOR: 101286910(ZAP70)
DLE: 111187417
PCAD: 102996375
ECB: 100147296(ZAP70)
EPZ: 103561441(ZAP70)
EAI: 106842544
MYB: 102259670(ZAP70)
MYD: 102775001(ZAP70)
MNA: 107543924
HAI: 109391988
DRO: 112315209
PALE: 102883976
RAY: 107509971
MJV: 108391417
LAV: 100666693
TMU: 101347632
MDO: 100025187(ZAP70)
SHR: 100916187
PCW: 110202117
GGA: 420086(ZAP70)
MGP: 100542877
CJO: 107325684
NMEL: 110388791
APLA: 101798888
ACYG: 106048412(ZAP70)
TGU: 100229988
LSR: 110478014
SCAN: 103821913
GFR: 102034810(ZAP70)
FAB: 101809285(ZAP70)
PHI: 102108601(ZAP70)
PMAJ: 107215340
CCAE: 111940227
CCW: 104697023
ETL: 114070354
FPG: 101916784(ZAP70)
FCH: 102059049
CLV: 102088841
EGZ: 104132036(ZAP70)
NNI: 104018770(ZAP70)
ACUN: 113489494
PADL: 103921148(ZAP70)
AAM: 106486099(ZAP70)
ASN: 102379235
AMJ: 102576066
PSS: 102446767
CMY: 102939519
CPIC: 101946149(ZAP70)
PVT: 110072432
PBI: 103049663
PMUR: 107282189
TSR: 106542969(ZAP70)
PMUA: 114588403
GJA: 107113429
XLA: 108706868 446840(zap70.L)
XTR: 448557(zap70)
NPR: 108798239
DRE: 553615(zap70)
SRX: 107731183 107745809
SANH: 107676994 107695253
SGH: 107548917 107585931
CCAR: 109060641 109071103
IPU: 108264986(Zap70)
PHYP: 113534995
AMEX: 103044019
EEE: 113575095
TRU: 101069105
TNG: GSTEN00019257G001
LCO: 104921819
NCC: 104944350(zap70)
MZE: 101466346
ONL: 100696446
OLA: 101170171
XMA: 102236845
XCO: 114151578
PRET: 103468233
CVG: 107097723
NFU: 107392881
KMR: 108238465
ALIM: 106516821(zap70)
AOCE: 111580186
CSEM: 103394926
POV: 109636582
LCF: 108896602
SDU: 111225667
SLAL: 111645387
HCQ: 109519137
BPEC: 110167942
MALB: 109961723
SASA: 106584369 106613845
OTW: 112242249 112250942
SALP: 111971408 111975278
ELS: 105011640
SFM: 108919908
PKI: 111860226
LCM: 102357488(ZAP70)
CMK: 103183477(zap70)
RTP: 109915343
DGT: 114515801
 » show all
Reference
  Authors
Kuroyama H, Ikeda T, Kasai M, Yamasaki S, Tatsumi M, Utsuyama M, Saito T, Hirokawa K
  Title
Identification of a novel isoform of ZAP-70, truncated ZAP kinase.
  Journal
Biochem Biophys Res Commun 315:935-41 (2004)
DOI:10.1016/j.bbrc.2004.01.127
  Sequence
[hsa:7535]

  All links  
Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (18)   
   KEGG PATHWAY (18)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (405)   
   KEGG GENES (153)   
   KEGG MGENES (95)   
   RefGene (152)   
   OC (5)   
Literature (1)   
   PubMed (1)   
All databases (430)   

Download RDF
DBGET integrated database retrieval system