KEGG   ORTHOLOGY: K07376
Entry
K07376                      KO                                     

Name
PRKG1
Definition
cGMP-dependent protein kinase 1 [EC:2.7.11.12]
Pathway
ko04022  cGMP-PKG signaling pathway
ko04270  Vascular smooth muscle contraction
ko04540  Gap junction
ko04611  Platelet activation
ko04713  Circadian entrainment
ko04714  Thermogenesis
ko04730  Long-term depression
ko04740  Olfactory transduction
ko04923  Regulation of lipolysis in adipocytes
ko04970  Salivary secretion
Disease
H00801  Familial thoracic aortic aneurysm and dissection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09154 Digestive system
   04970 Salivary secretion
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09156 Nervous system
   04730 Long-term depression
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09157 Sensory system
   04740 Olfactory transduction
    K07376  PRKG1; cGMP-dependent protein kinase 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K07376  PRKG1; cGMP-dependent protein kinase 1
   04714 Thermogenesis
    K07376  PRKG1; cGMP-dependent protein kinase 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K07376  PRKG1; cGMP-dependent protein kinase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.12  cGMP-dependent protein kinase
     K07376  PRKG1; cGMP-dependent protein kinase 1
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKG family
   K07376  PRKG1; cGMP-dependent protein kinase 1
Other DBs
GO: 0004692
Genes
HSA: 5592(PRKG1)
PTR: 744467(PRKG1)
PPS: 100975252(PRKG1)
PON: 100437791(PRKG1)
NLE: 100597697(PRKG1)
MCC: 703356(PRKG1)
MCF: 102122483(PRKG1)
CSAB: 103216192(PRKG1)
RRO: 104676729(PRKG1)
CJC: 100388016(PRKG1)
SBQ: 101043597(PRKG1)
MMU: 19091(Prkg1)
MCAL: 110285294(Prkg1)
MPAH: 110313055(Prkg1)
RNO: 54286(Prkg1)
CGE: 100768615(Prkg1)
NGI: 103732508(Prkg1)
HGL: 101708361(Prkg1)
OCU: 100008694(PRKG1)
CFA: 609616(PRKG1)
VVP: 112931969(PRKG1)
AML: 100481505(PRKG1)
UMR: 103661993(PRKG1)
UAH: 113258870(PRKG1)
ELK: 111145213
FCA: 101097420(PRKG1)
PTG: 102969150(PRKG1)
PPAD: 109255410(PRKG1)
AJU: 106969513(PRKG1)
BTA: 282004(PRKG1)
BOM: 102279305(PRKG1)
BBUB: 102407722(PRKG1)
CHX: 102182753(PRKG1)
OAS: 443010(PRKG1)
SSC: 733640(PRKG1)
CFR: 102509252(PRKG1)
CDK: 105085256(PRKG1)
BACU: 103012801(PRKG1)
LVE: 103071917(PRKG1)
OOR: 101279276(PRKG1)
DLE: 111172539(PRKG1)
PCAD: 102991499(PRKG1)
ECB: 100071872(PRKG1)
EAI: 106847454(PRKG1)
MYB: 102255009(PRKG1)
MNA: 107543282(PRKG1)
HAI: 109387521(PRKG1)
DRO: 112307314(PRKG1)
PALE: 102884723(PRKG1)
RAY: 107515478(PRKG1)
LAV: 100662471(PRKG1)
MDO: 100023016(PRKG1)
SHR: 100928746(PRKG1)
PCW: 110199927(PRKG1)
OAA: 100073431(PRKG1)
GGA: 423682(PRKG1)
MGP: 100540173(PRKG1)
CJO: 107315639(PRKG1)
NMEL: 110390491(PRKG1)
APLA: 101802614(PRKG1)
ACYG: 106030263(PRKG1)
TGU: 100229896(PRKG1)
LSR: 110474019(PRKG1)
SCAN: 103823826(PRKG1)
GFR: 102041315(PRKG1)
FAB: 101816835(PRKG1)
PHI: 102105641(PRKG1)
PMAJ: 107207071(PRKG1)
CCW: 104695105(PRKG1)
ETL: 114065114(PRKG1)
FPG: 101914750(PRKG1)
FCH: 102051167(PRKG1)
CLV: 102098659(PRKG1)
EGZ: 104125151(PRKG1)
NNI: 104013515(PRKG1)
ACUN: 113481922(PRKG1)
ASN: 102385836(PRKG1)
AMJ: 102573015(PRKG1)
CMY: 102942713(PRKG1)
CPIC: 101953224(PRKG1)
PMUA: 114597269(PRKG1)
XLA: 108696071 108697357(prkg1.S)
XTR: 100494278(prkg1)
NPR: 108797031(PRKG1)
DRE: 394005(prkg1a) 566430(prkg1b)
SANH: 107654050
SGH: 107557353(prkg1)
IPU: 108274270(prkg1)
PHYP: 113527432
AMEX: 103047830(prkg1)
EEE: 113577006(prkg1)
TRU: 101061256(prkg1)
TNG: GSTEN00016387G001
LCO: 104927466
NCC: 104955830
MZE: 101466538
ONL: 100694992
OLA: 100049290(prkg1)
XMA: 102235247
XCO: 114138474
PRET: 103476798
CVG: 107098368
NFU: 107376029
KMR: 108242381
ALIM: 106513507(prkg1) 106528217
AOCE: 111575530(prkg1)
CSEM: 103387682(prkg1)
POV: 109632737
LCF: 108897326
SDU: 111235208
SLAL: 111670023(prkg1)
HCQ: 109528789
BPEC: 110157105
MALB: 109962157(prkg1)
SFM: 108932765 108939676(prkg1)
PKI: 111853690(prkg1)
LCM: 102357627
CMK: 103180883(prkg1)
RTP: 109927508
BFO: 118411480 118412576 118412578
CIN: 100184124
SPU: 589462
APLC: 110973758 110982046
DME: Dmel_CG10033(for) Dmel_CG3324(Pkg21D) Dmel_CG4839(CG4839)
DER: 6540897 6541099 6542539
DSE: 6613265 6617296
DSI: Dsimw501_GD22740(Dsim_GD22740) Dsimw501_GD22942(Dsim_GD22942) Dsimw501_GD23660(Dsim_GD23660)
DYA: Dyak_GE14825 Dyak_GE15942 Dyak_GE18902
DAN: 6497481 6497690
DSR: 110178188 110182603 110187360
DPO: Dpse_GA10020 Dpse_GA17377 Dpse_GA18468
DPE: 6588824 6589026 6595699
DMN: 108162046 108162419 108163582
DWI: 6642441 6644123
DGR: Dgri_GH10498 Dgri_GH13187
DMO: Dmoj_GI17764 Dmoj_GI18016
DAZ: 108609997 108611824
DNV: 115562010 115563626
DHE: 111599114 111601364
DVI: 6628026 6628367
MDE: 101894230 101894351 101900584
LCQ: 111677667 111681972
AGA: AgaP_AGAP008585 AgaP_AGAP008863 AgaP_AGAP009798
AAG: 5567008 5569682 5577470
AALB: 109397574 109433057 109621380 109621502 115268590
CQU: CpipJ_CPIJ006121
AME: 406092(For) 551714
BIM: 100744786
BTER: 100628631
CCAL: 108631693
OBB: 114878681
SOC: 105202008
MPHA: 105835361
AEC: 105148710
ACEP: 105627059
PBAR: 105427696
VEM: 105562546
HST: 105180461
DQU: 106741445
CFO: 105255628
LHU: 105678094
PGC: 109861390
OBO: 105280702
PCF: 106784179
NVI: 100117965 100119839
CSOL: 105361340
MDL: 103578414
TCA: 657149
DPA: 109536702 109546365
ATD: 109595188 109603865
NVL: 108561083 108561485
BMOR: 692605(PKG-I)
BMAN: 114250737
DPL: KGM_208453
PMAC: 106712155
PRAP: 110996662
HAW: 110376116
TNL: 113492093
PXY: 105381837
API: 100168151
DNX: 107170171
AGS: 114124896
RMD: 113560773
BTAB: 109030563 109043112
CLEC: 106662224 106663991
PHU: Phum_PHUM189890 Phum_PHUM596920
ZNE: 110836511 110837257
FCD: 110847879
DPX: DAPPUDRAFT_194528 DAPPUDRAFT_207381
PVM: 113813818
ISC: IscW_ISCW007896
TUT: 107363105
CSCU: 111625343
PTEP: 107436702 107446305
CEL: CELE_F55A8.2(egl-4)
LGI: LOTGIDRAFT_127769 LOTGIDRAFT_210612
PCAN: 112565934 112573499
CRG: 105335784 105345094
MYI: 110451175
LAK: 106156342 106181988
SMM: Smp_168670
NVE: 5509991
EPA: 110249033
AMIL: 114960266
PDAM: 113677276
SPIS: 111344883
HMG: 100201371(prkg1)
TAD: TRIADDRAFT_30166
PFA: PF3D7_1436600
PFD: PFDG_03615
PFH: PFHG_00276
PYO: PY17X_1009800
PCB: PCHAS_100910(PC000298.03.0)
PBE: PBANKA_1008200
PKN: PKH_131265
PVX: PVX_084705
PCY: PCYB_132230
TAN: TA04955
TPV: TP03_0511
CPV: cgd8_750
CHO: Chro.80094
TET: TTHERM_00013270 TTHERM_00105520 TTHERM_00193700 TTHERM_00442770
TPS: THAPSDRAFT_1553 THAPSDRAFT_21108
PIF: PITG_11102
 » show all
Reference
  Authors
Sausbier M, Schubert R, Voigt V, Hirneiss C, Pfeifer A, Korth M, Kleppisch T, Ruth P, Hofmann F
  Title
Mechanisms of NO/cGMP-dependent vasorelaxation.
  Journal
Circ Res 87:825-30 (2000)
DOI:10.1161/01.RES.87.9.825
  Sequence
[mmu:19091]

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Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (20)   
   KEGG PATHWAY (20)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (18596)   
   KEGG GENES (286)   
   KEGG MGENES (319)   
   RefGene (17952)   
   OC (39)   
Protein sequence (88)   
   UniProt (82)   
   SWISS-PROT (6)   
Literature (1)   
   PubMed (1)   
All databases (18711)   

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