KEGG   ORTHOLOGY: K07408
Entry
K07408                      KO                                     
Symbol
CYP1A1
Name
cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00380  Tryptophan metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map01100  Metabolic pathways
map04913  Ovarian steroidogenesis
map05204  Chemical carcinogenesis - DNA adducts
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05417  Lipid and atherosclerosis
Reaction
R02354  
R02355  
R03089  
R03408  
R03629  melatonin,NADPH---hemoprotein reductase:oxygen oxidoreductase
R07000  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07001  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07021  1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07022  1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07079  benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07080  benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07081  benzpyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07085  benzo[a]pyrene-7,8-diol,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07087  9-hydroxybenzo[a]pyrene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07098  trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07099  trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R08390  
R08392  
R09418  
R09423  
R09442  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05207 Chemical carcinogenesis - receptor activation
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05208 Chemical carcinogenesis - reactive oxygen species
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Genes
HSA: 1543(CYP1A1)
PTR: 453744(CYP1A1)
PPS: 100976184(CYP1A1)
GGO: 101129522
PON: 100457153
PPYG: 129014419
NLE: 100585507
HMH: 116481900
SSYN: 129482256
MCC: 678694(CYP1A1)
MCF: 102129994(CYP1A1)
MTHB: 126960000
MNI: 105490958
CSAB: 103245331(CYP1A1)
CATY: 105600061
PANU: 101001307
TGE: 112627760
MLEU: 105530835
RRO: 104672151
RBB: 108531476
TFN: 117070364
PTEH: 111529702
CANG: 105505165
CJC: 100393083(CYP1A1)
SBQ: 101038217
CIMI: 108298444(CYP1A1)
ANAN: 105716625 135275116
CSYR: 103271646
MMUR: 105854864
LCAT: 123624369
PCOQ: 105807306
OGA: 100955410
MMU: 13076(Cyp1a1)
MCAL: 110301270
MPAH: 110328033
RNO: 24296(Cyp1a1)
MCOC: 116071961
ANU: 117698968
MUN: 110558545
CGE: 100751269
MAUA: 101844540
PROB: 127231800
PLEU: 114690337
MORG: 121445349
MFOT: 126507531
AAMP: 119808952
NGI: 103736921
HGL: 101707509
CPOC: 100135512(Cyp1a1)
CCAN: 109701505
DORD: 105982352
DSP: 122098438
NCAR: 124977051
MMMA: 107137939
OCU: 100328613
OPI: 101533768
TUP: 102484009
GVR: 103588057
CFA: 100686778(CYP1A1)
CLUD: 112675585
VVP: 112908776
VLG: 121484958
NPO: 129506483
AML: 100473028
UMR: 103678992
UAH: 113240972
UAR: 123790682
ELK: 111153267
LLV: 125105138
MPUF: 101676222
MNP: 131999167
MLK: 131835779
NVS: 122893452
ORO: 101382250
EJU: 114206471
ZCA: 113910089
MLX: 118003748
NSU: 110583893
LWW: 102739666
FCA: 554347(CYP1A1)
PYU: 121041992
PCOO: 112855107
PBG: 122468425
PVIV: 125168946
LRUF: 124508019
PTG: 102966263
PPAD: 109262691
PUC: 125910157
AJU: 106979443
HHV: 120235772
BTA: 282870(CYP1A1)
BOM: 102283235
BIU: 109575587
BBUB: 102399021
BBIS: 104990991
CHX: 102170823
OAS: 100170113(CYP1A1)
BTAX: 128066562
ODA: 120875451
CCAD: 122419730
MBEZ: 129550459
SSC: 403103(CYP1A1)
CFR: 102518111
CBAI: 105069192
CDK: 105087262
VPC: 102530468
BACU: 103008057
BMUS: 118891077
LVE: 103071513
OOR: 101287158
DLE: 111177818
PCAD: 102984326
PSIU: 116749907
NASI: 112410978
ECB: 100062285(CYP1A1)
EPZ: 103552317
EAI: 106831264
MYB: 102262349
MYD: 102762200
MMYO: 118675915
MLF: 102437172
MDT: 132212050
PKL: 118728867
EFUS: 103300190
MNA: 107535216
DRO: 112301821
SHON: 118987754
AJM: 119041322 119041329
PDIC: 114492343
PHAS: 123825280
MMF: 118643668
PPAM: 129064162
HAI: 109396247
RFQ: 117024155
PALE: 102892046
PGIG: 120597850
PVP: 105306836
RAY: 107510533
MJV: 108388606
TOD: 119237890
SARA: 101550604
SETR: 126015044
LAV: 100665901
TMU: 101359275
ETF: 101661225
DNM: 101423437
MDO: 100029871
GAS: 123232970
SHR: 100927711
AFZ: 127551979
PCW: 110213927
TVP: 118828075 118828076
OAA: 100080942(CYP1A1)
ZVI: 118084457
STOW: 125424760
BBEL: 109480286
SCLV: 120326955 120337706 120347324
LPIC: 129258591 129274985
PVUL: 126810086 126812565 126815240 126823790 126825192
GAE: 121368990
HRF: 124120352 124120359 124131529 124140277
HRJ: 124268175 124276990 124282406
CRG: 105329067
CANU: 128190897
OED: 125647398 125648732
MMER: 123540564 123540605 123541431 123546444 123546459 123546828 123549057 123557949 123562948 123562951
RPHI: 132713371 132719301 132727684 132731161 132731163 132733404 132733414 132736383 132738690 132744217 132754874 132757640
DPOL: 127850854
MAEA: 128206276 128206748 128228746 128236623
ATEN: 116286948 116286970 116287897
XEN: 124435028 124452841 124452890
HSY: 130646034
 » show all
Reference
PMID:2989797
  Authors
Jaiswal AK, Gonzalez FJ, Nebert DW
  Title
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
  Journal
Nucleic Acids Res 13:4503-20 (1985)
DOI:10.1093/nar/13.12.4503
  Sequence
[hsa:1543]
Reference
PMID:3019683
  Authors
Kawajiri K, Watanabe J, Gotoh O, Tagashira Y, Sogawa K, Fujii-Kuriyama Y
  Title
Structure and drug inducibility of the human cytochrome P-450c gene.
  Journal
Eur J Biochem 159:219-25 (1986)
DOI:10.1111/j.1432-1033.1986.tb09857.x
  Sequence
[hsa:1543]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (33)   
   KEGG ENZYME (1)   
   KEGG REACTION (21)   
   KEGG RCLASS (11)   
Gene (447)   
   KEGG GENES (215)   
   KEGG MGENES (21)   
   RefGene (198)   
   OC (13)   
Literature (2)   
   PubMed (2)   
All databases (505)   

Download RDF
KEGG   ORTHOLOGY: K17690
Entry
K17690            Tight     KO                                     
Symbol
CYP3A5
Name
cytochrome P450 family 3 subfamily A5 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map00982  Drug metabolism - cytochrome P450
map01100  Metabolic pathways
map05204  Chemical carcinogenesis - DNA adducts
Reaction
R02356  
R03408  
R08286  
R08287  
R08390  
R08391  
R08392  
R09404  
R09408  
Disease
H01633  High blood pressure
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
   00982 Drug metabolism - cytochrome P450
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K17690  CYP3A5; cytochrome P450 family 3 subfamily A5
Genes
HSA: 1577(CYP3A5)
PTR: 737374(CYP3A5)
PPS: 100976333(CYP3A5)
GGO: 101147010
PON: 100434899
PPYG: 129041703
NLE: 100591599
HMH: 116810915
SSYN: 129489601
MCC: 678692(CYP3A5)
MCF: 102146134(CYP3A5)
MTHB: 126950477
MNI: 105497418
CSAB: 103246770(CYP3A5)
PANU: 100997418
TGE: 112621194
MLEU: 105543710
RRO: 104672095
RBB: 108538163
TFN: 117072035
PTEH: 111526378
CANG: 105513065
CJC: 100404952(CYP3A5) 100405792(CYP3A90)
SBQ: 101037736
CIMI: 108308035(CYP3A5)
ANAN: 105719457(CYP3A90) 105719458(CYP3A5)
 » show all
Reference
PMID:2732228
  Authors
Aoyama T, Yamano S, Waxman DJ, Lapenson DP, Meyer UA, Fischer V, Tyndale R, Inaba T, Kalow W, Gelboin HV, et al.
  Title
Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine.
  Journal
J Biol Chem 264:10388-95 (1989)
  Sequence
[hsa:1577]
Reference
PMID:14562963
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (20)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
   KEGG RCLASS (10)   
Gene (30)   
   KEGG GENES (28)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (69)   

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KEGG   ORTHOLOGY: K17691
Entry
K17691            Tight     KO                                     
Symbol
CYP3A7
Name
cytochrome P450 family 3 subfamily A7 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00830  Retinol metabolism
map01100  Metabolic pathways
map05204  Chemical carcinogenesis - DNA adducts
Reaction
R03408  
R08390  
R08392  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K17691  CYP3A7; cytochrome P450 family 3 subfamily A7
Genes
HSA: 100861540(CYP3A7-CYP3A51P) 1551(CYP3A7)
PTR: 129135235 737263(CYP3A7)
PPS: 100967578 100975985(CYP3A67)
GGO: 101147362 115935323
PON: 100435763 100436403
PPYG: 129041699 129041702
NLE: 115830387
HMH: 116810916
SSYN: 129489595 129489605
MCC: 100144394(CYP3A7)
MCF: 102145015(CYP3A7)
MTHB: 126950476
MNI: 105497398
CSAB: 103246767 103246772(CYP3A7)
CATY: 105584398
PANU: 100997059
TGE: 112621196
MLEU: 105543709 105543712
TFN: 117072036
 » show all
Reference
PMID:2722762
  Authors
Komori M, Nishio K, Ohi H, Kitada M, Kamataki T
  Title
Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450.
  Journal
J Biochem 105:161-3 (1989)
DOI:10.1093/oxfordjournals.jbchem.a122632
  Sequence
[hsa:1551]
Reference
PMID:14562963
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (8)   
   KEGG PATHWAY (8)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
   KEGG RCLASS (3)   
Gene (29)   
   KEGG GENES (28)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (50)   

Download RDF
KEGG   ORTHOLOGY: K07424
Entry
K07424                      KO                                     
Symbol
CYP3A
Name
cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00591  Linoleic acid metabolism
map00830  Retinol metabolism
map01100  Metabolic pathways
map05204  Chemical carcinogenesis - DNA adducts
map05207  Chemical carcinogenesis - receptor activation
Reaction
R02356  
R03408  
R07055  
R07056  
R08390  
R08391  
R08392  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
   00591 Linoleic acid metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
   05207 Chemical carcinogenesis - receptor activation
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07424  CYP3A; cytochrome P450 family 3 subfamily A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07424  CYP3A; cytochrome P450 family 3 subfamily A
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP3 family
   K07424  CYP3A; cytochrome P450 family 3 subfamily A
Genes
CATY: 105584469
CSYR: 103261808 103277234
MMUR: 105868221 105868329 109729598
LCAT: 123631584 123631585 123631588 123631589
PCOQ: 105806022 105806023
OGA: 100949611
MMU: 100041375(Cyp3a41b) 100041449(Cyp3a59) 13112(Cyp3a11) 13113(Cyp3a13) 13114(Cyp3a16) 337924(Cyp3a44) 53973(Cyp3a41a) 56388(Cyp3a25) 622127(Cyp3a57)
MCAL: 110287807 110288178 110294273 110294771
MPAH: 110312811 110313181 110314995 110315701 110315884
RNO: 170509(Cyp3a62) 171352(Cyp3a9) 252931(Cyp3a18) 25642(Cyp3a23-3a1) 266682(Cyp3a2) 690383(Cyp3a71-ps)
MCOC: 116070965 116071005 116071007 116104705 116104706 116104707
ANU: 117697807 117697808 117697809 117697948 117698139 117698393
MUN: 110543942 110544068 110544433 110566940 110566943 132650676 132650978 132651015 132651152 132651158 132651174 132651235
CGE: 100766524 100767391 100773059 100773351
MAUA: 101831686 101831958 101832126 101836914 101839056
PROB: 127237130 127237200 127237281 127237283 127237293
PLEU: 114684379 114684384 114684395 114685030 114685037 114687273 114687275 114687326 114687328 114687403 114687726 114688299 114688300 114689169 114689336 119087101
MORG: 121445245 121445965 121446005 121446030 121446074 121464879 121464904 121464905 121464906 121464907 121464909 121464910
MFOT: 126492995 126492996 126492997 126495128 126495325 126495330 126495331 126495469
AAMP: 119824363 119824438 119824441 119824659 119824660 119824661 119825569 119825570
NGI: 103726479 103726480
HGL: 101700489
CPOC: 100301487(Cyp3a17) 100379244(Cyp3a14) 100379245(Cyp3a15) 100719785 100734717 100734998
CCAN: 109701918 109702004
DORD: 105990893 105990894 105990905 105997303 106001866
DSP: 122113684 122113686 122113687
PLOP: 125367229 125367244 125367253 125367258 125367481
NCAR: 124969866 124969867 124969879
MMMA: 107133689 107155930 107155932
OCU: 100328954(CYP3A6)
OPI: 101519834 101521480 101531312 101532260
TUP: 102494214
GVR: 103606316 103606317
CFA: 415127(CYP3A26) 489851
CLUD: 112646265 112646266 112663009
VVP: 112909983 112935742 112935745
VLG: 121486274 121488071
NPO: 129519424 129519425 129519426 129519435
AML: 100472647 105235077
UMR: 103669994 103669998 103669999
UAH: 113249444 113249757 113267901 113267902
UAR: 123777260 123777277 123777328
ELK: 111145601 111145602 111145608
LLV: 125090641 125090643 125090644
MPUF: 101673108 101676428 101676727 101682130
MNP: 132026519 132026526 132027276
MLK: 131819107 131819108 131819109 131819112
NVS: 122895350 122895351 122895359 122895360
ORO: 101368110
EJU: 114203387 114203610 114203807
ZCA: 113932025 113932071 118355995 118355996
MLX: 117999383
NSU: 110571974
LWW: 102725583 102745213
FCA: 100642187(CYP3A132) 100652377(CYP3A131)
PYU: 121017808 121017809
PCOO: 112860079
PBG: 122471975 122471976
PVIV: 125154085 125154086
LRUF: 124519213 124519264 124519355
PTG: 102957386(CYP3A131) 102957670
PPAD: 109251249 109251250
PUC: 125928549
AJU: 106981196 106981197
HHV: 120225539 120227384 120227978
BTA: 282214(CYP3A28) 507988(CYP3A74) 517246(CYP3A24) 526682(CYP3A76)
BOM: 102284132 102284405 102284686 102284966
BBUB: 102405595 102405926 102406240 102412400
BBIS: 104992728 104992729 104992730 104992731
CHX: 102168966 102181382 102191011 102191297
OAS: 100170111(CYP3A24) 101110202 101110727 114108597
BTAX: 128043210 128043211 128043212 128043215
ODA: 120879764 120879780 120879796 120879810
CCAD: 122432817 122432818 122432819 122432820 122432889
MBEZ: 129545708 129545709 129545710 129545713 129545715
SSC: 100126281(CYP3A46) 100144468(CYP3A22) 403324(CYP3A29)
CFR: 102505615 102512762 102514805
CBAI: 105077048 105077059 105077600
CDK: 105099349 105099350
VPC: 102525384 102527302 102538990
BACU: 103014952
BMUS: 118880767
LVE: 103081108
OOR: 117200989
PCAD: 102979137
PSIU: 116739882
NASI: 112399912
ECB: 100067041(CYP3A93) 100067064(CYP3A89) 100067084(CYP3A94) 100067109(CYP3A95) 100067131(CYP3A96) 100067154(CYP3A97) 102149219
EPZ: 103542550 103564390 103564391 103564392 103566374 103566375
EAI: 106825164 106825167 106832275 106832276 106832277
MYB: 102263738
MYD: 102756525 102762686
MMYO: 118656485 118656498 118662413
MLF: 102432141 102432464 111827801
MDT: 132232293 132232294 132232295 132232296
PKL: 118703231
EFUS: 103286223 103286224
MNA: 107540865 107540873
DRO: 112314814 112314817
SHON: 118975258 118981795 119002040
AJM: 119041580 119064049
PDIC: 114492349 114492360
PHAS: 123818103 123818117
MMF: 118641936 118642420
PPAM: 129083833 129083834
HAI: 109378053
RFQ: 117024570 117024571 117024573
PGIG: 120587429 120607798
PVP: 105309521 105310085
RAY: 107508095 107509342
MJV: 108386989
TOD: 119241615
SARA: 101542879 101543157 101543423 101543688
SETR: 126030421 126030427
LAV: 100658511 100658793 100677295 100677576
TMU: 101349229 101350229
ETF: 101656690
DNM: 101412004 101412143 101442567 101443605
MDO: 100010698 100010745 100010783 100010820 100013114 100013238
GAS: 123231169 123231171 123233944
SHR: 100918011 100930770
AFZ: 127563615 127563631
PCW: 110201906 110201912 110201914 110201917
TVP: 118830187 118833852 118833853 118833855 118833856 118833859 118833860 118833862 118841246 118841312 118858287
OAA: 100082218 100082250 100082275 100089880 100091970
GGA: 414832(CYP3A5) 416477(CYP3A4)
PCOC: 116237418 116237434
MGP: 678668(CYP3A80) 678669(CYP3A37)
CJO: 107320762 107320785
TPAI: 128079132 128079222
LMUT: 125700893 125700907
NMEL: 110405948 110406034
APLA: 101799374 101799795
ACYG: 106032071 106032170
CATA: 118249116 118249123
AFUL: 116495297 116495307
TGU: 100223162 100226034
LSR: 110481576 110481678
SCAN: 103817855
PMOA: 120513096 120513276
OTC: 121334460 121334499
PRUF: 121350797 121350802
GFR: 102042286 102042456
FAB: 101815550 101818071
OMA: 130259488 130259489
PHI: 102105124 102105300
PMAJ: 107210919 107211377
CCAE: 111936102 111936103
CCW: 104684806 104684807
CBRC: 103615418 103615579
ETL: 114060192 114060195
ZAB: 102061839 102065830
ZLE: 135454036 135454270
ACHL: 103804084 103804579
SVG: 106849722 106849729
MMEA: 130575723 130575724
HRT: 120759610 120759741
SATI: 136367916 136367917
FPG: 101911664 101911836
FCH: 102049918 102050092
CCRI: 104158338
NNT: 104409143 104409144
SHAB: 115606566 115607356
ACUN: 113485635 113485844
TALA: 104362186
ACHC: 115335935 115335988
HALD: 104317094 104323105
HLE: 104833569 104833570
AGEN: 126034276 126034277
GCL: 127022237 127022391
CSTI: 104563857 104563859
LDI: 104355107 104355108
MNB: 103768448 103768449
DPUB: 104297083 104297093
AVIT: 104269979
BRHI: 104489439 104495828
EGZ: 104132595 104132596
NNI: 104015095 104015219
PCRI: 104031415 104035981
PCAO: 104053499 104053500
PADL: 103913536 103913537
AFOR: 103904874 103904875
FGA: 104079087 104079088
GSTE: 104254938 104259688
CLV: 102087823 102088003
MUI: 104537429 104537430
PGUU: 104463044 104463510
PLET: 104620401 104621601
EHS: 104510560 104510695
CMAC: 104477935 104482323
CUCA: 104062520 104062521
TEO: 104382772
BREG: 104640169 104640176
OHA: 104331210 104331242
ACAR: 104523907
CPEA: 104385248 104385249
CVF: 104290883 104290884
RTD: 128914111 128914308
AAM: 106495217 106495220
AROW: 112974281 112974330
NPD: 112959868
TGT: 104576357 104580447
DNE: 112992903 112992936
SCAM: 104153925
ASN: 102368695 102368945 102369208
AMJ: 102570482(CYP3A) 102570712
CPOO: 109314709
GGN: 109294316 109294549
PSS: 102447293 102447714
CMY: 102939531 102943719 119567199 119567257
CCAY: 125643929 125644066 125644068
DCC: 119862703 119862704 119862865
CPIC: 101944980 101945909
TST: 117883793 117883831 117883976
CABI: 116817552 116817553 116817555
MRV: 120373865 120373952 120374095
ACS: 100555955 100557851 100558240 100558437
ASAO: 132782168 132782169 132782170 132782171
PVT: 110083729 110091550
SUND: 121914161 121914420 121914620 121937545 121937546
PBI: 103050164 103050666
PMUR: 107290607 107290608 107290609 107290618 107290631
CTIG: 120315615 120315616 120315617 120315618 120315772 120315817
TSR: 106538078 106556514
PGUT: 117660294 117676798 117676801 132709672
APRI: 131185220 131185221 131185343
PTEX: 113438804 113438806 113438972
NSS: 113426999 113427000 113430149
VKO: 123025019 123025020 123025117
PMUA: 114584054 114584055 114584056 114584534
PRAF: 128401308 128401309 128401310 128401653
ZVI: 118077805 118092624 118092626 118092751 118092845 118092916
HCG: 128336421 128336516 128336761 128336840
GJA: 107117318 107117320 107123864 107125821
STOW: 125431001 125431204 125431383
EMC: 129338280 129338423 129338495 129338607 129338698 129340197
XLA: 100037189(cyp3a4.2.L) 108718493 398964(cyp3a4.1.L) 495363(cyp3a5.L)
XTR: 100487054 100487846 100494419(cyp3a4.2) 548503(cyp3a4.3)
NPR: 108790579 108790580 108804467
RTEM: 120921209 120937082
BBUF: 120990135 120998158
BGAR: 122934027 122935596 122940690
MUO: 115476721 115476722
GSH: 117345596 117369093
DRE: 324340(cyp3c1) 492759(cyp3c3) 553969(cyp3a65) 558473(cyp3c2) 558541(cyp3c4)
SRX: 107720069 107740699 107748444 107748668 107758392
SANH: 107662714 107680745 107680747 107703406 107703407
SGH: 107574731 107575037 107581712 107591821
CCAR: 109061438 109061483 109081405 109081406
CAUA: 113038900 113083757 113091962 113100638 113100639
CGIB: 127949467 127949468 127951781 127951782 128018251
PTET: 122333178 122333197 122359260 122359579
LROH: 127160427 127160450 127161747 127164342
OMC: 131536899 131538018
PPRM: 120466740 120489978
RKG: 130088313 130088314 130095015
MAMB: 125269666 125269683 125269685 125271550
CIDE: 127508533 127508534 127508535 127508536 127508537 127518105
CERY: 137012543 137012551 137017785 137017787 137032020(cyp3a65)
MASI: 127443759 127444867 127450185 127452137
TROS: 130552779 130561008
TDW: 130426693 130426694 130432883
MANU: 129432564 129432577 129432579 129443796
IPU: 108257387 108258748 108258760 108258762 108258764
IFU: 128600579 128602479 128602482 128602484 128602486
PHYP: 113524841 113524842 113524843 113536086 113536087
SMEO: 124376214 124377941 124377943
TFD: 113650795 113650810 113658449 113658450 113658453 125140143
TVC: 132839163 132839166 132839222 132839599 132863970 132863971
TRN: 134328567 134329445 134329623 134331241
AMEX: 103024636 103030124 103031034 125780417
CMAO: 118797885 118797886 118797887 118797888 118797890 118797891 118797892 118805725 118805726
EEE: 113575193 113591419
CHAR: 105890717 105894071 105896823 105896847 105908606 122131936
TRU: 101067951 101069124 101075886 101076110 115246460
TFS: 130526852 130530109 130530550 130533604 130533819
TNG: GSTEN00006530G001 GSTEN00014304G001
LCO: 104925565 104931688 109139171
NCC: 104952908 104955725 104962336 104962345
TBEN: 117482177 117482178 117494023 117499753 117499755
CGOB: 115008590 115008600 115010822 115010832 115020285
PGEO: 117447762 117449153 117459686
GACU: 117540686 117556156 117560895
EMAC: 134864255 134864256 134870197
ELY: 117248526 117248527 117248593 117254556 117254557 117258895
EFO: 125882842 125882864 125892110 125903289 125903291 125903292
PLEP: 121941720 121941722 121946723 121954678
SLUC: 116043019 116061623 116062163
ECRA: 117947469 117952941 117960056
ESP: 116692833 116704014 116705067
PFLV: 114565538 114572351 114574051
GAT: 120820327 120825021 120825023 120825839 120828825
PPUG: 119199469 119214489 119217509 119217510 119217512 119222282
AFB: 129091966 129092282 129095409 129096529 129100336 129116791
CLUM: 117730623 117730648 117733538 117744269 117744286
PSWI: 130189610 130189611 130207472
MSAM: 119898745 119898746 119905426 119916942
SCHU: 122874047 122874050 122883225 122884459
CUD: 121507778 121507903 121507904 121508311 121510858 121511323 121518053
ALAT: 119023388 119027172 119027178 119027190 119027210 119033330 119033962
MZE: 101471241 101471528 101476506 101476786 101477063 101477343 101478178
ONL: 100700506 100700772 100702245 100702592 100703397 100703674 102077052
OAU: 116312360 116312361 116318820 116324823 116324841 116324864 116325740 116332155 116335296 116335305
OLA: 100125817(cyp3a40) 101155293 101155406(cyp3a) 101155538
OML: 112137328 112137329 112137330 112139012 112140211 112161368 112161722
CSAI: 133441902 133441909 133457119 133463364 133463436 133464180
XMA: 102219031 102222638 111606488 111606645 111606646 111608645
XCO: 114138344 114138479 114144494 114144495
XHE: 116713050 116713051 116719333 116719911 116719912
PRET: 103476433 103476434
PFOR: 103137413 103154817 103154825
PLAI: 106940464 106941173 106943212 106943213
PMEI: 106904953 106905839 106905841 106911665 106912355
GAF: 122829005 122829006 122829007 122842051 122842281 122842285
PPRL: 129359669 129360109 129376871 129376882
CVG: 107089887
CTUL: 119783709 119783710 119783711 119790264
GMU: 124859475 124868738 124868739
NFU: 107375867 107388844
KMR: 108244157 108244648
ALIM: 106515376 106519642
NWH: 119413204 119422463 119430470
AOCE: 111572716 111574386 111579974
MCEP: 125004587 125004588 125018446 125018447 125019812
CSEM: 103387006
POV: 109633951
SSEN: 122770520 122771328 122771329 122771349 122777362 122781646 122781800
HHIP: 117764331 117764332 117764333 117775167
HSP: 118111468 118111470 118111575 118118788 118118967
PPLT: 128430690 128441989 128441990 128441991 128441992 128441993 128441994 128453104
SMAU: 118283391 118283392 118311907 118317276 118317408
LCF: 108877940 108896255 108899374 108899376
SDU: 111216640 111216641 111227399
SLAL: 111645298 111663275 111663301
XGL: 120796826 120800946 120800947 120804233
HCQ: 109511276 109512513 109528492
SSCV: 125978516 125988913
SBIA: 133496530 133506524 133509982
PEE: 133404349 133409441 133413303
PTAO: 133485946 133489818
BPEC: 110156796 110158274
MALB: 109970725
BSPL: 114858441 114858446 114859104 114859105 114870618 114870620
SJO: 128357806 128373363 128373364 128377472 128377489 128377503 128377512 128377523
SASA: 106568073 106591782 106591899 106593341 106594168(CP3AR)
STRU: 115168548 115178486 115178487 115178488 115178489 115178667 115178668 115178669 115178672
OTW: 112214885 112221342 112222821 112239077
OMY: 110492562 110511934 110514644 110514645 110514797 110518927 118936632 118940217 118947742
OGO: 124002708 124002724 124003120 124023292 124023293 124025063 124045570
ONE: 115115032 115125444
OKI: 109869080 109879569 109879570 109879571 109879572 109879574 109879575 116353018 116359007 116359008 116371141
OKE: 118359571 118381063 118381482 127922813 127926754
SALP: 112075201
SNH: 120042124 120042129 120042130 120042131 120042132 120042133 120061442
CCLU: 121546081 121570147 123489043 123491268
ELS: 105009625 105009626 105009627
SFM: 108922555 108926524 108927524
PKI: 111845480 111854069
AANG: 118216635 118216713 118220759 118220761 118229823
LOC: 102684669 102684871 102693837
PSPA: 121301050 121320988 121330840
ARUT: 117405680 117418522 117431525
PSEX: 120541920 120543247
LCM: 102365730
CMK: 103185125
RTP: 109917931 109922256 125487134
CPLA: 122541976 122560449 122560798 122560799
HOC: 132825492 132825493 132825494
LERI: 129706648 129706649 129713715
PMRN: 116949655 116951671 116951672
LRJ: 133340949 133340950 133340951 133340952 133346278
BFO: 118406568 118414778 118414801 118426698 118427220 118428229
BBEL: 109463787 109464201 109467470 109468932 109469473 109470714 109471346 109471464 109475399 109476094 109477106 109478808 109484389 109485683 109485810 109485811 109485812 109485813 109486688
SCLV: 120332300 120332302 120332303 120332304 120332305 120332318 120332320 120332321 120340954 120344192 120344193 120344194 120344200 120344219 120344234 120344872 120344967 120347406 120347618
LPIC: 129256331 129264488 129265125 129265784 129265789 129266424 129266425 129267363 129267369 129267371 129269689 129269749
ARUN: 117288752 117288760 117288972 117289098 117289099 117289265 117289266 117295059 117299914 117300572 117305235
AJC: 117114624
BCOO: 119066914 119067186 119069853 119074078 119074427 119074939 119081225 119082306 119083480 119083786 119084267 119085713
OLG: 117604369
AROA: 105683931
SOY: 115882271 115887743 115888532 115888893
AGRG: 126733843 126734715 126737050 126737169 126746903
CSET: 123309823
AGB: 108904006 108904007 108910638 108916436
LDC: 111507913 111511395 111512159 111518298
PPYR: 116160074 116165566 116168351 116168967 116169445 116170548 116174035 116174328 116177747 116177853 116177854 116178557 116179633 116179793 116179836
OTU: 111428189 111428677
MJU: 123869601
PRAP: 110992351
ZCE: 119830198
SLIU: 111348641
CCRN: 123305527
HHAL: 106680993 106691458 106691459
NLU: 111051489 120356101
HVI: 124367652
MQU: 128982112
BROR: 134530302
IEL: 124159494
DMK: 116920246 116928047 116928048 116928049 116929127 116929158 116929172 116929574 123475190
PJA: 122242307 122248200 122248209 122248210 122256421 122262146 122262149 122265384 122267182 122267183
PCHN: 125025862 125028557 125041727 125041728 125041797 125041815 125041861 125042027 125042163 125042164 125042189 125042256
HAME: 121854946 121855268 121863787 121871947 121878761
PCLA: 123751244 123762231 123764970 123774302
CQD: 128685180 128689823 128692543 128696236 128696237 128696634 128697048 128697049 128700051 128703733 128704862
PTRU: 123500630 123502395 123506022 123511482 123514769 123514893 123518726
ESN: 126981786 126982537 126985756 126985761 126998828 126998829 126998830 126998831 126998886 126998887 126998943
MNZ: 135206798 135216150 135216154 135217409
EAF: 111712343 111712470
LSM: 121115942 121121551 121122879
TCF: 131882578 131882582 131882736 131891483 131891652
PPOI: 119091548 119091910 119092516 119095550 119095862 119096334 119096766 119096767 119096808 119097136 119097363 119103773 119105682 119108907 119112164 119113493 119114109 119114281 119114282 119114298 119114354 119114363 119114377 119114393
DSV: 119431959 119437320 119437467 119439984 119440080 119441397 119441753 119444791 119445714 119446100 119446101 119446102 119446103 119448902 119448927 119449670 119449672 119449675 119452771 119453582 119454247 119455653 119455670 119455672 119456161 119456162 119456163 119456164 119456180 119456182 119456244 119456533 119456756 119462278
RSAN: 119372212 119372213 119372260 119377827 119381582 119381583 119382948 119382950 119385600 119389244 119389357 119390062 119390063 119390949 119391230 119391235 119391811 119393442 119393443 119393452 119393662 119393913 119393975 119393981 119394821 119397365 119398625 119398626 119398977 119399528 119399630 119399658 119400363 119406578
RMP: 119160033 119160887 119160987 119161198 119161207 119161215 119167314 119168643 119169954 119171697 119171707 119171708 119171843 119172114 119172769 119172772 119173990 119174000 119179006 119179162 119179163 119179642 119182255 119183193 119185251 119185481 119186999 119187388
VDE: 111246682 111247963 111251253
VJA: 111260837 111261642 111269868 111272084
DFR: 124489972 124490590 124491405 124492684 124493771 124495984 124495985 124495987 124496224 124496225 124500531 124500532 124500570
CVS: 136968160 136971881 136972181 136973541 136974060 136974784 136974786 136974787 136978153 136978211 136981052 136983015 136983016 136983018 136983079 136983948 136986187 136986261 136986262 136986310 136986381 136986937 136986938 136986945 136986946 136986947 136986948 136986949 136987788 136988485 136988501 136988766 136988889 136988890 136988891 136988892 136988893 136988895 136988896 136988897 136988898 136990566 136990571 136990573
ABRU: 129960878 129962540 129962543 129963531 129964201 129965449 129965908 129971418 129971563 129972418 129980815 129980816 129980817 129981114 129981243 129981249 129981255 129981719 129981722 129981723 129990245 129991480
UDV: 129219841 129221989 129221990 129222144 129222876 129222877 129223057 129223061 129223073 129223416 129223442 129225125
SDM: 118184000 118189134 118199031
LPOL: 106460260 106472174
PMEO: 129591730 129591731 129592254 129593278 129596853 129596854 129597884 129597885
PVUL: 126807995 126807996 126809619 126815142 126815262 126815654 126815806 126825145 126828006 126828112 130010220
BGT: 106051039 106052179 106052498 106053436 106053957 106053958 106061608 106061610 106061612 106061620 106062365 106062679 106063357 106063676 106065086 106066214 106068469 106073255 106073257 106074587 106074589 106077913 106078832 106079470 106079585
GAE: 121372980 121376062 121379748 121381936
HRF: 124110308 124114395 124114676 124115565 124116408 124116440 124116794 124121587 124124725 124124819 124132691 124133885 124137120 124139642 124141696 124141698 124141708 124141762 124142422 124142992 124143001 124143013 124143022 124143023 124143073 124143074 124149278 124150323 124150346 124151330 124152675
HRJ: 124253624 124253866 124255864 124255889 124256900 124263719 124264464 124264465 124264466 124264470 124264471 124265082 124265814 124269548 124271109 124271110 124272227 124272229 124274142 124278061 124278062 124278084 124278086 124278495 124279834 124280060 124280961 124282708 124282768 124282769 124282777 124282778 124282779 124282887 124282890 124283644 124283767 124284397 124286777 124286779 124286783 124286795 124286802 124286806 124286809 124291272
CRG: 105320785 105320786 105322665 105325143 105331505 105335480 105335491 105343044 105344634 105345458 105347766 105348863 117685407 117687816
CANU: 128163032 128164766 128165030 128167428 128171763 128171764 128173243 128183523 128186881 128192209 128192210
CVN: 111102272 111111230 111111879 111111880 111111883 111111884 111115967 111119379 111120211 111121332 111121956 111121957 111127588 111127589 111136547
OED: 125645775 125647541 125666150 125666792 125668692 125668693 125671292 125671777 125674615 125674617 125674618 125674620 125674622 125680583
MYI: 110440738 110442381 110463252
PMAX: 117315082 117317854 117317855 117317884 117318186 117320939 117335613 117335747 117335779 117335780 117335781 117335782 117335783 117335874 117335984 117335988 117336095 117343439 117343440 117343496
MCAF: 127700684 127705384 127719044 127720136 127720457 127720458 127720497
MMER: 123522877 123531405 123539699 123540772 123542611 123542780 123543436 123555131 123563764 123564412 123564413 123564414
RPHI: 132717786 132724771 132725696 132733710 132734281 132740994 132740995 132745742 132750732
DPOL: 127835578 127841943 127841950 127847180 127855620 127857890 127858022 127862317 127866046 127868518 127870881 127872351 127882098
MAEA: 128213436 128214623 128218415 128218910 128218911 128221103 128221701 128222225 128225146 128225970 128228693 128229119 128233643 128233649 128235279 128239593 128242424 128244908
OBI: 106870822
OSN: 115220571 115220577 115224699 115224818 115224836 115228176
LJP: 135465697 135466057 135475471 135475555 135476099 135476100 135476101 135476332 135476380 135476439 135476591 135476674 135476870 135476872 135476881 135476901 135476902 135479544 135479583 135479720 135479721 135479722
LLON: 135483085 135486597
ATEN: 116288794 116289344 116289345 116294106 116296667 116297188 116297196 116298736 116303286 116305462
HSY: 130635775
RES: 135684278 135684281 135684282 135684284
TDC: 119344950
RIE: OCT59_005865 OCT59_010343 OCT59_015390 OCT59_021511
 » show all
Reference
PMID:3785219 (CYP3A2)
  Authors
Gonzalez FJ, Song BJ, Hardwick JP
  Title
Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation.
  Journal
Mol Cell Biol 6:2969-76 (1986)
DOI:10.1128/MCB.6.8.2969
  Sequence
[rno:266682]
Reference
PMID:1339292 (CYP3A11)
  Authors
Yanagimoto T, Itoh S, Muller-Enoch D, Kamataki T
  Title
Mouse liver cytochrome P-450 (P-450IIIAM1): its cDNA cloning and inducibility by dexamethasone.
  Journal
Biochim Biophys Acta 1130:329-32 (1992)
DOI:10.1016/0167-4781(92)90447-8
  Sequence
[mmu:13112]
Reference
PMID:2001406 (CYP3A12)
  Authors
Ciaccio PJ, Graves PE, Bourque DP, Glinsmann-Gibson B, Halpert JR
  Title
cDNA and deduced amino acid sequences of a dog liver cytochrome P-450 of the IIIA gene subfamily.
  Journal
Biochim Biophys Acta 1088:319-22 (1991)
DOI:10.1016/0167-4781(91)90072-t
  Sequence
[cfa:415127]
Reference
PMID:11284050 (CYP3A25)
  Authors
Dai D, Bai R, Hodgson E, Rose RL
  Title
Cloning, sequencing, heterologous expression, and characterization of murine cytochrome P450 3a25*(Cyp3a25), a testosterone 6beta-hydroxylase.
  Journal
J Biochem Mol Toxicol 15:90-9 (2001)
DOI:10.1002/jbt.4
  Sequence
[mmu:56388]
Reference
PMID:21781753 (CYP3A28)
  Authors
Natsuhori M, van Raak M, Ligtenberg M, Kleij L, Ten Berge D, Zweers-Zeilmaker WM, de Groene EM, van Miert AS, Witkamp RF, Horbach GJ
  Title
Isolation of a bovine full length cytochrome P450 (CYP3A) cDNA sequence and its functional expression in V79 cells.
  Journal
Environ Toxicol Pharmacol 3:17-24 (1997)
DOI:10.1016/s1382-6689(96)00133-0
  Sequence
[bta:282214]
Reference
PMID:9682441 (CYP3A29)
  Authors
Nissen PH, Wintero AK, Fredholm M
  Title
Mapping of porcine genes belonging to two different cytochrome P450 subfamilies.
  Journal
Anim Genet 29:7-11 (1998)
DOI:10.1046/j.1365-2052.1998.00225.x
  Sequence
[ssc:403324]
Reference
PMID:10775455 (CYP3A41)
  Authors
Sakuma T, Takai M, Endo Y, Kuroiwa M, Ohara A, Jarukamjorn K, Honma R, Nemoto N
  Title
A novel female-specific member of the CYP3A gene subfamily in the mouse liver.
  Journal
Arch Biochem Biophys 377:153-62 (2000)
DOI:10.1006/abbi.2000.1747
  Sequence
[mmu:53973]
Reference
PMID:16414346 (CYP3C1)
  Authors
Corley-Smith GE, Su HT, Wang-Buhler JL, Tseng HP, Hu CH, Hoang T, Chung WG, Buhler DR
  Title
CYP3C1, the first member of a new cytochrome P450 subfamily found in zebrafish (Danio rerio).
  Journal
Biochem Biophys Res Commun 340:1039-46 (2006)
DOI:10.1016/j.bbrc.2005.12.110
  Sequence
[dre:324340]
Reference
PMID:14562963
  Authors
McArthur AG, Hegelund T, Cox RL, Stegeman JJ, Liljenberg M, Olsson U, Sundberg P, Celander MC
  Title
Phylogenetic analysis of the cytochrome P450 3 (CYP3) gene family.
  Journal
J Mol Evol 57:200-11 (2003)
DOI:10.1007/s00239-003-2466-x

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical reaction (13)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
   KEGG RCLASS (5)   
Gene (3702)   
   KEGG GENES (1978)   
   KEGG MGENES (204)   
   RefGene (1517)   
   OC (3)   
Literature (9)   
   PubMed (9)   
All databases (3739)   

Download RDF
KEGG   ORTHOLOGY: K07412
Entry
K07412                      KO                                     
Symbol
CYP2B
Name
cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00590  Arachidonic acid metabolism
map00830  Retinol metabolism
map01100  Metabolic pathways
map05207  Chemical carcinogenesis - receptor activation
Reaction
R03408  
R07001  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07048  
R07050  
R07051  
R07052  
R08390  
R08391  
R08392  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
   00590 Arachidonic acid metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07412  CYP2B; cytochrome P450 family 2 subfamily B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07412  CYP2B; cytochrome P450 family 2 subfamily B
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07412  CYP2B; cytochrome P450 family 2 subfamily B
Genes
PCOQ: 105820475 105820477 105820598
OGA: 105888244
MMU: 13088(Cyp2b10) 13089(Cyp2b13) 13090(Cyp2b19) 13094(Cyp2b9) 243881(Cyp2b23)
MCAL: 110288440 110288965 110297861 110298448 110298729 110298847
MPAH: 110336742
RNO: 103691072(Cyp2b14) 103691092 24300(Cyp2b1) 286953(Cyp2b3) 292728(Cyp2b21) 29295(Cyp2b12) 361523(Cyp2b2) 685222(Cyp2b15)
MCOC: 116100420 116101862 116101866
ANU: 117710642 117710646 117714125
MUN: 110541208 110541305 110561195 110566202
CGE: 100759787 100760248 100762876 100763166 100763652 100765152 100765441 113837198 113838302
MAUA: 101833813 101844221 101844487 101844759 110339371 110339777 121135526 121135543
PROB: 127238392 127238393 127238561 127238677
PLEU: 114681539 114681540 114685303 114685307 114685311 114709908
MORG: 121449160 121449161 121449216 121449230 121449273 121449308 121449313
MFOT: 126491014 126491015 126491016 126491474 126492551 126492557 126492560 126494574 126494580
AAMP: 119820529 119820530 119820531 119820542 119820560 119820577 119820578 119821048 119821050
NGI: 103734444 103734445
HGL: 101700457 101713256
CPOC: 100719649 100720199 100728848
CCAN: 109680163 109703253
DORD: 106000902 106002870
DSP: 122097399 122097400
PLOP: 125338988 125338999
NCAR: 124966667 124966693 124966955
MMMA: 107151434 107151634
OCU: 100327257(CYP2B4) 100328947(CYP2B5) 100328948 100353574 127486083
OPI: 101530662
TUP: 102479421 102494535
GVR: 103600497
CFA: 474177(CYP2B6)
CLUD: 112645436
VVP: 112928354
VLG: 121485519
NPO: 129499612
AML: 100464347 100471209
UMR: 103677389 103677390
UAH: 113243545 113243547
UAR: 123782650 123782733
ELK: 111161484 111161535
LLV: 125089181 125089182
MPUF: 101673760 101674033
MNP: 132005762 132005763
MLK: 131817740 131817741
NVS: 122912057 122912058
ORO: 101366852 101385757
EJU: 114202558
ZCA: 113936245 113936360
MLX: 118022638
NSU: 110590260
FCA: 105259649(CYP2B6) 105260134
PYU: 121026667 121026668
PCOO: 112851322
PBG: 122494012 122494013
PVIV: 125152576 125153441 125153673
LRUF: 124511102 124511733
PPAD: 109261476
PUC: 125915742
AJU: 128313207 128313238
HHV: 120243430
BTA: 504769(CYP2B6) 530571(CYP2B39)
BOM: 102282243 102287777
BIU: 109572039 109573028
BBUB: 102389842 102403709
BBIS: 104995375 104995377
CHX: 102169213 102177329 108633257 108634920
OAS: 105614373 114117814 114117992
BTAX: 128063721 128063735 128063836 128063962
ODA: 120872403 120872470 120873272 120873273 120873274
CCAD: 122420841 122420842 122421523 122421559
MBEZ: 129546790
SSC: 102165015 403104(CYP2B22)
CFR: 102506939 102510644
CBAI: 105062874 105062875
CDK: 105093362 105093363
VPC: 102540531 102541423
ECB: 100068569 100068603
EPZ: 103562352 103562353 103567950
EAI: 106843260 106843311 106843807 123281262
MYB: 102245131
MYD: 102751643
MMYO: 118674745
MLF: 102434131 102434449
MDT: 132216860
PKL: 118702365
EFUS: 103284293
DRO: 112319965
AJM: 119042877 119064581
PDIC: 114511724
PHAS: 123823834
MMF: 118639252
PPAM: 129076628
HAI: 109376598 109376600
RFQ: 117035075
PGIG: 120595325
PVP: 105311372 105311521
RAY: 107521826
MJV: 108405662
TOD: 119248644 119249343 119249344
SARA: 101545542 101545812 101546075 101546339 101546853 101547109 101552590
SETR: 126027511 126028124 126028126 126028128 126028134 126028139 126028181 126028182 126028540 126028542
LAV: 100667350 100677786
TMU: 101341442
ETF: 101648079 101648692
DNM: 101434321 101439883
MDO: 100018927
GAS: 123242991 123242992
SHR: 100931571 105749943
AFZ: 127556219
PCW: 110198215 110198316 110203819 110204171
TVP: 118837371 118837372 118837766 118837784
OAA: 100074363
CABI: 116833843
ASAO: 132780095
PCHN: 125047440
HAME: 121875618
PCLA: 123773186
HAZT: 108665744 108667155 108682011
PPOI: 119094960
ABRU: 129968506
UDV: 129220285 129233366
SDM: 118179726 118184819
CANU: 128178189
OED: 130048152
PMAX: 117329675 117330042
RPHI: 132737651
OSN: 115217139 115217246 115217542 115231109 115231157
 » show all
Reference
PMID:6306654 (CYP2B2)
  Authors
Mizukami Y, Sogawa K, Suwa Y, Muramatsu M, Fujii-Kuriyama Y
  Title
Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.
  Journal
Proc Natl Acad Sci U S A 80:3958-62 (1983)
DOI:10.1073/pnas.80.13.3958
  Sequence
[rno:361523]
Reference
PMID:3396451 (CYP2B3)
  Authors
Labbe D, Jean A, Anderson A
  Title
A constitutive member of the rat cytochrome P450IIB subfamily: full-length coding sequence of the P450IIB3 cDNA.
  Journal
DNA 7:253-60 (1988)
DOI:10.1089/dna.1988.7.253
  Sequence
[rno:286953]
Reference
PMID:3219345 (CYP2B9 CYP2B10)
  Authors
Noshiro M, Lakso M, Kawajiri K, Negishi M
  Title
Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA.
  Journal
Biochemistry 27:6434-43 (1988)
DOI:10.1021/bi00417a035
  Sequence
[mmu:13094 13088]
Reference
PMID:2116765 (CYP2B11)
  Authors
Graves PE, Elhag GA, Ciaccio PJ, Bourque DP, Halpert JR
  Title
cDNA and deduced amino acid sequences of a dog hepatic cytochrome P450IIB responsible for the metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl.
  Journal
Arch Biochem Biophys 281:106-15 (1990)
DOI:10.1016/0003-9861(90)90419-y
  Sequence
[cfa:474177]
Reference
PMID:1445240 (CYP2B12)
  Authors
Friedberg T, Grassow MA, Bartlomowicz-Oesch B, Siegert P, Arand M, Adesnik M, Oesch F
  Title
Sequence of a novel cytochrome CYP2B cDNA coding for a protein which is expressed in a sebaceous gland, but not in the liver.
  Journal
Biochem J 287 ( Pt 3):775-83 (1992)
DOI:10.1042/bj2870775
  Sequence
[rno:29295]
Reference
PMID:8294026 (CYP2B15)
  Authors
Nakayama K, Suwa Y, Mizukami Y, Sogawa K, Fujii-Kuriyama Y
  Title
Cloning and sequencing of a novel rat cytochrome P450 2B-encoding gene.
  Journal
Gene 136:333-6 (1993)
DOI:10.1016/0378-1119(93)90490-t
  Sequence
[rno:685222]
Reference
PMID:9799616 (CYP2B19)
  Authors
Keeney DS
  Title
The novel skin-specific cytochrome P450 Cyp2b19 maps to proximal chromosome 7 in the mouse, near a cluster of Cyp2 family genes.
  Journal
Genomics 53:417-9 (1998)
DOI:10.1006/geno.1998.5533
  Sequence
[mmu:13090]
Reference
PMID:11159754 (CYP2B21)
  Authors
Brookman-Amissah N, Mackay AG, Swann PF
  Title
Isolation and sequencing of the cDNA of a novel cytochrome P450 from rat oesophagus.
  Journal
Carcinogenesis 22:155-60 (2001)
DOI:10.1093/carcin/22.1.155
  Sequence
[rno:292728]
Reference
PMID:16315095 (CYP2B22)
  Authors
Kawahigashi H, Hirose S, Ozawa K, Ido Y, Kojima M, Ohkawa H, Ohkawa Y
  Title
Analysis of substrate specificity of pig CYP2B22 and CYP2C49 towards herbicides by transgenic rice plants.
  Journal
Transgenic Res 14:907-17 (2005)
DOI:10.1007/s11248-005-0199-x
  Sequence
[ssc:403104]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (16)   
   KEGG ENZYME (1)   
   KEGG REACTION (9)   
   KEGG RCLASS (6)   
Gene (350)   
   KEGG GENES (303)   
   KEGG MGENES (2)   
   RefGene (40)   
   OC (5)   
Literature (9)   
   PubMed (9)   
All databases (388)   

Download RDF
KEGG   ORTHOLOGY: K07414
Entry
K07414                      KO                                     
Symbol
CYP2D
Name
cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map04726  Serotonergic synapse
Reaction
R03408  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07414  CYP2D; cytochrome P450 family 2 subfamily D
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K07414  CYP2D; cytochrome P450 family 2 subfamily D
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07414  CYP2D; cytochrome P450 family 2 subfamily D
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07414  CYP2D; cytochrome P450 family 2 subfamily D
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07414  CYP2D; cytochrome P450 family 2 subfamily D
Genes
MMU: 13101(Cyp2d10) 13105(Cyp2d9) 223706(Cyp2d34) 380997(Cyp2d12) 545123(Cyp2d11) 56448(Cyp2d22) 68444(Cyp2d13) 71754(Cyp2d40) 76279(Cyp2d26)
MCAL: 110288527 110288999 110289146 110310240 110310283 110310469 110310542
MPAH: 110334675 110334761 110334795 110334832 110334835 110334854 110334866 110334867 110334914
RNO: 171522(Cyp2d4) 24303(Cyp2d3) 25053(Cyp2d2) 266684(Cyp2d1) 286963(Cyp2d5)
MCOC: 116076713 116081639 116104676
ANU: 117718541 117718592 117718616 117718617 117718815 117718837 117719282 117719283 117719285
MUN: 110552077 110552090 110552092 110554094 110554095 110554097 110554122 132646027 132655789
CGE: 100750508 100771066 100774408 100774698
MAUA: 101840984 110340366 121142578 121142579 121142580
PROB: 127225857 127225862 127225863
PLEU: 114688909 114689233 114689234 114694310 114694323 114694324 114694388
MORG: 121461043 121461044 121461045 121461047 121461174 121461196 121461216 121461217 121461277 121461358
MFOT: 126492060 126492074 126492078 126492091 126492101 126492113 126492121
AAMP: 119823022 119823023 119823024 119823025 119823027 119823028 119823358
NGI: 103743450 103743452 103743453 103743454 103743455 103743515
HGL: 101722985 101723802 101724171 101724763
CPOC: 100169696(Cyp2d16) 100714485 100715041 100715321 100715799 100716263 100716545 100717002 100717652 100717930 100718401 100718679 100718953 100719230 100719511 100722262 100722818
DORD: 105992055 105992057 105992059
DSP: 122123535 122123536 122123537 122123538 122123539
PLOP: 125357495 125357505 125357517 125357560
NCAR: 124982053 124982056
MMMA: 107134215 107134216 107155828
OCU: 100316858(CYP2D24) 100348527
OPI: 101535122 101535375 101535547
TUP: 102487958
CFA: 415120(CYP2D15)
CLUD: 112666661
VVP: 112934002
VLG: 121490798
NPO: 129511717
AML: 100472452
UMR: 103674066
UAH: 113241702
UAR: 123780676
ELK: 111157504
LLV: 125106071
MPUF: 101672586
MNP: 132020449
MLK: 131839562
NVS: 122891125
ORO: 101372264
EJU: 114218371
ZCA: 113921588
NSU: 110578248
FCA: 100500743(CYP2D6)
PYU: 121040241
PCOO: 112863693
PBG: 122472841
PVIV: 125171245
LRUF: 124501756
PTG: 102964225(CYP2D6)
PPAD: 109265656
PUC: 125920374
AJU: 106979940
HHV: 120234310
BTA: 282211(CYP2D14) 785824(CYP2D43)
BOM: 102287765
BIU: 109559878 109559879
BBUB: 102406860 102410630
BBIS: 104991248
CHX: 102169002 102177333 102179192 108634669
OAS: 100568286(CYP2D6) 101112384 114114084 114114086
BTAX: 128047526 128047527 128047529 128047530 128048265 128048268 128048328 128048332
ODA: 120859250 120859306
CCAD: 122423707
MBEZ: 129536920 129537031
SSC: 397687(CYP2D25)
CFR: 102510557
CBAI: 105073057
CDK: 105091879
VPC: 102542551
BACU: 103007607
BMUS: 118902635
OOR: 101276966
DLE: 111186231
PCAD: 102987821
PSIU: 116760501
NASI: 112394613
ECB: 100056087 100070895 100070905 100070945(CYP2D50) 100070962 100070990 100146596 100147428 100147480
EPZ: 103542204 103543525 103544255
EAI: 106845102 106845104 106848497 106848498 106848499 106848501
MYB: 102241505
MYD: 102753093
MMYO: 118651850 118651851
MLF: 102419632 102420161 102420688
MDT: 132225850 132225851 132225852
PKL: 118712077 118712078
EFUS: 129149863 129149865
MNA: 107534962
DRO: 112321792
SHON: 119002464
AJM: 119060173
PDIC: 114512883
PHAS: 123816041
MMF: 118624451
PPAM: 129077874
HAI: 109371456
RFQ: 117029426 117029427
PALE: 102886763
PGIG: 120602932
PVP: 105298024
RAY: 107505566
TOD: 119247190 119247197
SARA: 101546292 101553347
SETR: 126006237 126006364 126006365 126006366
LAV: 100655392 100656155
TMU: 101341338
ETF: 101653633 101654377
MDO: 100018032
SHR: 100926939
AFZ: 127538463
PCW: 110205862
TVP: 118851388
OAA: 100086809
GGA: 417981(CYP2D6)
PCOC: 116233524 116233525
MGP: 100548322
CJO: 107313299
TPAI: 128073448
LMUT: 125688268
NMEL: 110390936
APLA: 101804496
ACYG: 106046243(CYP2D6)
CATA: 118246669
AFUL: 116502036
TGU: 100222415
LSR: 110483129
SCAN: 103813311
PMOA: 120510076
OTC: 121342311
PRUF: 121361070
GFR: 102041048
FAB: 101821306
OMA: 130262301
PHI: 102108095
PMAJ: 107205209
CCAE: 111934339
CCW: 104696362
CBRC: 103618122
ETL: 114058074
ZLE: 135442458 135442459
ACHL: 103803233
SVG: 106856930
MMEA: 130588366
HRT: 120752195
SATI: 136361709(CYP2D6)
FPG: 101921852
FCH: 102048029
CCRI: 104161789
NNT: 104404490
SHAB: 115605360
ACUN: 113491562
TALA: 104365310
ACHC: 115352853
HALD: 104311000
HLE: 104833067
AGEN: 126047854
GCL: 127014896
CSTI: 104554977
LDI: 104351498
MNB: 103770438
DPUB: 104301982
AVIT: 104268282
BRHI: 104493764
EGZ: 104134346
NNI: 104021654
PCRI: 104034188
PCAO: 104048996
PADL: 103915260
AFOR: 103907790
FGA: 104070428
GSTE: 104254569
CLV: 102097622
MUI: 104544992
PGUU: 104468401
PLET: 104625226
EHS: 104503834
CMAC: 104485742
CUCA: 104055481
TEO: 104370504
BREG: 104634153
OHA: 104329836
ACAR: 104526639
CVF: 104295477
RTD: 128904057
AAM: 106488892
AROW: 112967724
DNE: 112984474
SCAM: 104137916
ASN: 102370106
AMJ: 102569264(CYP2D6)
CPOO: 109315960
GGN: 109295812
PSS: 102462176 102462423
CMY: 102929592 102934237 119564132 119564149 119564152
CCAY: 125629947 125629953
DCC: 119845208 119857069 119859094 119863104
CPIC: 101933422 101938829 101939092 101951050
TST: 117879730 117884169 117884792
CABI: 116828623 116829297 116832008 116838146
MRV: 120375915 120384786 120387859
ACS: 100558940
ASAO: 132769716 132775782 132775791 132776006 132776008
SUND: 121930834 121930835 121930836 121930926 121930928
VKO: 123019452 123033076
PMUA: 114605492 114605761
PRAF: 128422220 128422221 128422542
ZVI: 118091460
HCG: 128326384 128326385 128327536
GJA: 107122924 107123018
STOW: 125435351 125435354
EMC: 129335276 129335278 129335279 129335541 129335663 129336068
XLA: 108714516 108715021 108715777 108715778 379479(XB5769266.L) 444392 446878(cyp2d6.S)
XTR: 100145323 100494106 100495359 100495518 101731511 116410450 548436(cyp2d6)
NPR: 108794296 108804494
RTEM: 120941277 120945468
BBUF: 120978913 121001277
BGAR: 122938404 122943639
MUO: 115473043 115473053 115473059
GSH: 117353425 117353427 117353429 117353431
CMK: 103180618
RTP: 109920361
CPLA: 122564142 122564144
HOC: 132830269 132830353 132830397
LERI: 129694571 129710461 129710710 129710711 129710712
BFO: 118415899
BBEL: 109462641 109462737 109463451 109474841 109478605
SCLV: 120328227 120328855
LPIC: 129281320 129282009
ARUN: 117289920 117291149 117304831 117304898
BCOO: 119080033
HAZT: 108680212
TCF: 131883746
DSV: 119459121
SDM: 118190842
PMEO: 129581189 129585256
PVUL: 126817714 126818508 126821255 126821667 126821944
BGT: 106054490
GAE: 121366491 121381858 121389421
HRJ: 124257561 124266965 124291035
CRG: 105321692
CANU: 128160333 128161281 128161282 128186341 128192867
CVN: 111102456 111107265 111115387 111117535 111137052
OED: 125679044
PMAX: 117340548
MMER: 123531314 123542934 123547463 123559538
RPHI: 132717033 132717036 132718497 132722365 132722367 132743595 132747303 132747622 132751859 132753271
DPOL: 127832023 127847240 127867649
MAEA: 128210266 128231581 128233662 128235857
LJP: 135463059 135475195 135476667
LLON: 135483152
XEN: 124445683 124445684 124445685 124452615 124455699 124455827
 » show all
Reference
PMID:3582092 (CYP2D1 CYP2D2)
  Authors
Gonzalez FJ, Matsunaga T, Nagata K, Meyer UA, Nebert DW, Pastewka J, Kozak CA, Gillette J, Gelboin HV, Hardwick JP
  Title
Debrisoquine 4-hydroxylase: characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism.
  Journal
DNA 6:149-61 (1987)
DOI:10.1089/dna.1987.6.149
  Sequence
[rno:266684 25053]
Reference
PMID:2831949 (CYP2D9)
  Authors
Wong G, Kawajiri K, Negishi M
  Title
Gene family of male-specific testosterone 16 alpha-hydroxylase (C-P-450(16) alpha) in mouse liver: cDNA sequences, neonatal imprinting, and reversible regulation by androgen.
  Journal
Biochemistry 26:8683-90 (1987)
DOI:10.1021/bi00400a029
  Sequence
[mmu:13105]
Reference
PMID:1396678 (CYP2D14)
  Authors
Tsuneoka Y, Matsuo Y, Higuchi R, Ichikawa Y
  Title
Characterization of the cytochrome P-450IID subfamily in bovine liver. Nucleotide sequences and microheterogeneity.
  Journal
Eur J Biochem 208:739-46 (1992)
DOI:10.1111/j.1432-1033.1992.tb17242.x
  Sequence
[bta:282211]
Reference
PMID:7786018 (CYP2D15)
  Authors
Sakamoto K, Kirita S, Baba T, Nakamura Y, Yamazoe Y, Kato R, Takanaka A, Matsubara T
  Title
A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization.
  Journal
Arch Biochem Biophys 319:372-82 (1995)
DOI:10.1006/abbi.1995.1307
  Sequence
[cfa:415120]
Reference
PMID:7733969 (CYP2D16)
  Authors
Jiang Q, Voigt JM, Colby HD
  Title
Molecular cloning and sequencing of a guinea pig cytochrome P4502D (CYP2D16): high level expression in adrenal microsomes.
  Journal
Biochem Biophys Res Commun 209:1149-56 (1995)
DOI:10.1006/bbrc.1995.1617
  Sequence
[cpoc:100169696]
Reference
PMID:8910433 (CYP2D18)
  Authors
Kawashima H, Sequeira DJ, Nelson DR, Strobel HW
  Title
Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18* catalyzing imipramine N-demethylation.
  Journal
J Biol Chem 271:28176-80 (1996)
DOI:10.1074/jbc.271.45.28176
  Sequence
[rno:171522]
Reference
PMID:9425298 (CYP2D25)
  Authors
Postlind H, Axen E, Bergman T, Wikvall K
  Title
Cloning, structure, and expression of a cDNA encoding vitamin D3 25-hydroxylase.
  Journal
Biochem Biophys Res Commun 241:491-7 (1997)
DOI:10.1006/bbrc.1997.7551
  Sequence
[ssc:397687]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (803)   
   KEGG GENES (539)   
   KEGG MGENES (31)   
   RefGene (229)   
   OC (4)   
Literature (7)   
   PubMed (7)   
All databases (820)   

Download RDF
KEGG   ORTHOLOGY: K07409
Entry
K07409                      KO                                     
Symbol
CYP1A2
Name
cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00232  Caffeine metabolism
map00380  Tryptophan metabolism
map00591  Linoleic acid metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map00982  Drug metabolism - cytochrome P450
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map05204  Chemical carcinogenesis - DNA adducts
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
Reaction
R03408  
R03629  melatonin,NADPH---hemoprotein reductase:oxygen oxidoreductase
R07000  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07001  naphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07021  1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07022  1-nitronaphthalene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07055  
R07056  
R07098  trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07099  trichloroethene,NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
R07939  caffeine:oxygen oxidoreductase (N3-demethylating)
R07943  
R07945  
R08293  
R08294  
R08392  
R09405  
R09407  
R09408  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
   00591 Linoleic acid metabolism
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
   00982 Drug metabolism - cytochrome P450
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
   05207 Chemical carcinogenesis - receptor activation
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
   05208 Chemical carcinogenesis - reactive oxygen species
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07409  CYP1A2; cytochrome P450 family 1 subfamily A2
Genes
HSA: 1544(CYP1A2)
PTR: 735881(CYP1A2)
PPS: 100975837(CYP1A2)
GGO: 101130358
PON: 100172368(CYP1A2)
PPYG: 129014441
NLE: 100586622
HMH: 116481901
SSYN: 129482258
MCF: 102130662(CYP1A2)
MTHB: 126959999
MNI: 105490960
CSAB: 103245329(CYP1A2)
CATY: 105600060
PANU: 101002117
TGE: 112627775
MLEU: 105530834
RRO: 104672152
RBB: 108531494
TFN: 117071589
PTEH: 111529709
CANG: 105505164
CJC: 100392712(CYP1A2)
SBQ: 101037899
ANAN: 105714471 135276964
CSYR: 103271647
MMUR: 105854822
LCAT: 123624379
PCOQ: 105807254
OGA: 100955723
MMU: 13077(Cyp1a2)
MCAL: 110301271
MPAH: 110328034
RNO: 24297(Cyp1a2)
MCOC: 116071962
ANU: 117698970
MUN: 110558530
CGE: 100755851
MAUA: 101825565
PROB: 127231801
PLEU: 114690345
MORG: 121445350 121445351 121445352
MFOT: 126507532 126507533 126507534
AAMP: 119808953 119808954 119808956
NGI: 103736875
CPOC: 100135513(Cyp1a2)
CCAN: 109695949
DORD: 105982353 105982354 105982355
DSP: 122098436 122098439
PLOP: 125368231
NCAR: 124977052
MMMA: 107137940
OCU: 100328937
TUP: 102484432
GVR: 103588056
CFA: 494010(CYP1A2)
CLUD: 112675583 112675584
VVP: 112917417
VLG: 121484959
NPO: 129506143
AML: 100472774
UMR: 103678991
UAH: 113240971
UAR: 123790681
ELK: 111153221
LLV: 125105139
MPUF: 101677117
MNP: 131999166
MLK: 131835777
NVS: 122893016
ORO: 101381962
EJU: 114206434
ZCA: 113910367
MLX: 118002935
NSU: 110584050
LWW: 102742108
FCA: 554345(CYP1A2)
PYU: 121041994
PCOO: 112855160
PBG: 122468422
PVIV: 125168378
LRUF: 124508017
PTG: 102966939
PPAD: 109262688
PUC: 125910173
AJU: 106979449
HHV: 120235751
BTA: 503552(CYP1A2)
BOM: 102280158
BIU: 109575670
BBUB: 102399561
BBIS: 104991054
CHX: 102170554
OAS: 101109214
BTAX: 128066814
ODA: 120875452
CCAD: 122419767
MBEZ: 129550128
SSC: 100152910(CYP1A2)
CFR: 102518362
CBAI: 105069191
CDK: 105087261
VPC: 102530734
BACU: 103007560
BMUS: 118891291
LVE: 103071784
OOR: 101287407
DLE: 111177607
PCAD: 102984795
PSIU: 116749085
NASI: 112410949
ECB: 100062244(CYP1A2)
EPZ: 103552315
EAI: 106831265
MYB: 102262040
MYD: 102761918
MMYO: 118675919
MLF: 102437484
MDT: 132226266
MNA: 107535217
DRO: 112301801
SHON: 118987676
AJM: 119046569
PDIC: 114492026
PHAS: 123825158
MMF: 118637248
HAI: 109396253
RFQ: 117022727
PGIG: 120597823
PVP: 111732470
MJV: 108388607
TOD: 119237889
SARA: 101544097
SETR: 126015076
LAV: 100666189
TMU: 101359541
ETF: 101661749
DNM: 101424165 101426385 101432104
MDO: 100029908
GAS: 123232968
SHR: 116421952
AFZ: 127551978
PCW: 110213926
TVP: 118828084
TCF: 131883248
MMER: 123552212
HSY: 130644429
 » show all
Reference
PMID:3755823
  Authors
Jaiswal AK, Nebert DW, Gonzalez FJ
  Title
Human P3(450): cDNA and complete amino acid sequence.
  Journal
Nucleic Acids Res 14:6773-4 (1986)
DOI:10.1093/nar/14.16.6773
  Sequence
[hsa:1544]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (34)   
   KEGG ENZYME (1)   
   KEGG REACTION (19)   
   KEGG RCLASS (14)   
Gene (183)   
   KEGG GENES (160)   
   KEGG MGENES (5)   
   RefGene (7)   
   OC (11)   
Literature (1)   
   PubMed (1)   
All databases (245)   

Download RDF
KEGG   ORTHOLOGY: K07413
Entry
K07413                      KO                                     
Symbol
CYP2C
Name
cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00590  Arachidonic acid metabolism
map00591  Linoleic acid metabolism
map00830  Retinol metabolism
map01100  Metabolic pathways
map04726  Serotonergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map05204  Chemical carcinogenesis - DNA adducts
Reaction
R03408  
R07042  
R07043  
R07048  
R07050  
R07051  
R07052  
R07054  
R07055  
R07056  
R08390  
R08392  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
   00590 Arachidonic acid metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
   00591 Linoleic acid metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07413  CYP2C; cytochrome P450 family 2 subfamily C
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07413  CYP2C; cytochrome P450 family 2 subfamily C
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K07413  CYP2C; cytochrome P450 family 2 subfamily C
Genes
PON: 100449185
PPYG: 129006201
MCC: 100424240(CYP2C76)
MCF: 102114994(CYP2C76) 135965165
MTHB: 126962035 126962036
MNI: 105470210
CATY: 105576142 105581754
PANU: 101012275 101026117
TGE: 112631566
MLEU: 105553702 105553718
RRO: 104664669 104664684
RBB: 108543807 108543808
TFN: 117069747 117069809
PTEH: 111538683 111538726
CANG: 105527570
CJC: 100391987
SBQ: 101040831
CIMI: 108282285(CYP2C76)
ANAN: 105708280(CYP2C76)
CSYR: 103250328 103254835 103255987 103265697 103270233 103277163 110596230
MMUR: 105872488 105873460
LCAT: 123650042 123650046 123650138
PCOQ: 105818461 105824363
OGA: 100941342 100944925 100949727
MMU: 100043108(Cyp2c69) 107141(Cyp2c50) 13095(Cyp2c29) 13096(Cyp2c37) 13097(Cyp2c38) 13098(Cyp2c39) 13099(Cyp2c40) 226105(Cyp2c70) 226143(Cyp2c23) 404195(Cyp2c54) 433247(Cyp2c68) 545288(Cyp2c67) 69888(Cyp2c66) 72082(Cyp2c55) 72303(Cyp2c65)
MCAL: 110285234 110285299 110285416 110285739 110286013 110288497
MPAH: 110318652 110321409 110323738 110329470 110333565
RNO: 100361492(Cyp2c55) 100361547(Cyp2c7l1) 100911718 100912265(Cyp2c66) 120093077 120098584 134483996 134485234 171518(Cyp2c22) 171521(Cyp2c13) 25011(Cyp2c12) 29277(Cyp2c11) 29298(Cyp2c7) 293989(Cyp2c6v1) 499353(Cyp2c24) 83790(Cyp2c23)
MCOC: 116072985 116072994 116101173 116103883
ANU: 117695924 117704125 117704160 117707817 117707833 117710720 117710944 117711779 117712125 117714049 117714760 117715357
MUN: 110540047 110540048 110540049 110540723 110541031 110541449 110546312 110552973 110554760
CGE: 100751491 100751762 100751778 100752064 100752358 100753681 100754177 100754462 100756757 100757240 100757723 100772776 100773851 113830663 113834830
MAUA: 101823450 101829294 101830378 101831088 101831527 101832144 101832611 101841752 101842021
PROB: 127233403 127233429 127233439 127233441 127233442 127233443 127233444
PLEU: 114687277 114687280 114702470 114706456 114706863 114706876 114706883 114706891 114706892
MORG: 121453776 121453777 121453779 121453780 121453915 121453926 121453935 121453936 121453949 121453973 121453987 121453988 121453999 121454098 121454106 121454325 121454361 121454788
MFOT: 126503086 126511077 126511085
AAMP: 119808112 119808461 119808473 119808480 119808972 119811688 119814029 119818815 119824915 119824922
NGI: 103729081 103732440 103732443 103732444 103732445 103732447 103744062 103749112 103752530
HGL: 101708592 101710990
CPOC: 100716044 100719102
CCAN: 109675594 109686866 109686867
DORD: 105999354 105999358 105999359 105999360 105999362 105999363 105999364 105999365 105999366 106001658 106001659 106001669
DSP: 122115684 122115686 122115687 122115688 122115689 122115690 122115692 122115694 122115695 122115696 122115698 122115699 122115821 122115856 122115857
PLOP: 125342134 125346230 125346232 125346233 125346234 125346235 125346236 125346238 125346239 125346241 125346243
NCAR: 124984664 124984711 124984718 124984740 124984981 124985051 124985100 124985193 124985263 124985323 124985911 124985912 124985914
MMMA: 107149731 107149732 107149742 107149743
OCU: 100328549(CYP2C5) 100328924(CYP2C2) 100328933(CYP2C) 100328935(CYP2C30) 100328936(CYP2C14) 100328938(CYP2C16) 100345193 100346305 100346743(CYP2C1) 100349436(CYP2C4) 100353460 103351405
OPI: 101519662 101519910 101520157 101520641 101524854 101525811 101526220 101526786 101527195 101527783 101528381 101528927 101529516 101529922
TUP: 102467726 102501371 102503066
GVR: 103609510 103609514 103609927 103610437 103610588
CFA: 100688697 415122(CYP2C18)
CLUD: 112672099 112672554 112672584
VVP: 112917651 112917654 112928780
VLG: 121484666 121485285 121485560
NPO: 129493642 129493856 129493884
AML: 100468534 100470213 100471407
UMR: 103659697 103670756
UAH: 113243099 113251748 125282749
UAR: 123777781 123783991 123783992 123783994 123791300 123800006 123800347
ELK: 111144935 111144947
LLV: 125085077 125085209
MPUF: 101687589 101688450
MNP: 132016643 132016644
MLK: 131828623 131828625
NVS: 122898982 122898983
ORO: 101365057 101365655 101383285
EJU: 114205328 114205474 114221836
ZCA: 113919561 113923367 113923499
MLX: 118024006 118024011
NSU: 110589090 110589295
LWW: 102741683 102742186
FCA: 101089396(CYP2C41) 101089804
PYU: 121037024 121037025
PCOO: 112854419 112854424
PBG: 122493051 122493053
PVIV: 125148038 125148039
LRUF: 124506212 124507012
PTG: 102957879 102958169
PPAD: 109264681 109264682
PUC: 125932819 125933400
AJU: 106965832 106965834
HHV: 120230588 120230589 120230594
BTA: 505468(CYP2C88) 510380(CYP2C89) 511498(CYP2C23) 535243(CYP2C90) 616593(CYP2C87) 785540(CYP2C281)
BOM: 102266046 102268262 102279786 102280731 102282716 102285833
BIU: 109553136 109553148 109553149 109553151 109553186 109579059
BBUB: 102391944 102392701 102398418 102401059 102401347
BBIS: 104983529 104983530 104985773 104990182 104990186 105002722
CHX: 100861186 102169851 102180722 102185708 102185739 102188304 106503891 108633308
OAS: 100534653(CYP2C19) 100568290(CYP2C18) 101106641 101107056 101107486 101120535
BTAX: 128067928 128067935 128067944 128067982 128067983 128067984 128068009
ODA: 120873493 120873494 120873527 120873718 120873719 120873724
CCAD: 122446106 122446108 122446110 122446562 122446680 122446729 122446733
MBEZ: 129555150 129555520 129555964 129555969 129555971 129555972 129555974 129555975
SSC: 100739741 403106(CYP2C32) 403107(CYP2C33) 403108(CYP2C34) 403110(CYP2C36) 403111(CYP2C42) 403215(CYP2C49)
CFR: 102505530 102520553 102520945 102521185 102521601
CBAI: 105081748 105081809 105081810 105081811 105081813
CDK: 105084249 105084251 105084253 105084254 105084313
VPC: 102533247 102534924 102535318 102535571 102541494
BACU: 103017669
BMUS: 118882389
LVE: 103084494
OOR: 101280390 101281073
DLE: 111172397
PCAD: 102978514 102990258
PSIU: 116741310 116741704
NASI: 112392977
ECB: 100061367 100061400 100061440(CYP2C92) 100061470 100061502 100061579(CYP2C113) 100061609 100070400
EPZ: 103555431 103555432 103559687 103559691 103563727 103564575
EAI: 106828038 106842115 106842116 106842117 106842118 106846082 106846096 106846703
MYB: 102259201 102262062
MYD: 102757298 102761651
MMYO: 118669861 118669862 118669933 118669936
MLF: 102425332 102439008 102439973
MDT: 132214162 132214163 132214164 132214227
PKL: 118719320 118719322 118719385
EFUS: 103288419 103288420 103288471
MNA: 107542552 107542558 107543271
DRO: 112300219
SHON: 118988005 118999525
AJM: 119064549
PDIC: 114496070 114496071 114496072 114497455
PHAS: 123828810 123828873 123829140 123829141 123829142
MMF: 118632032 118632707
PPAM: 129077061 129077108
HAI: 109379576 109380905 109380969 109380970
RFQ: 117036205 117036207 117036211 117036262 117036412
PALE: 102891905
PGIG: 120608941 120609277 120609279
PVP: 105301394
MJV: 108409895
TOD: 119234464 119234519
SARA: 101538594 101538863 101539126 101539748 101540186 101541249 101541695 101542671 101545907 101546049 101546518 101547469 101548282 101548987 101549253 101549522 101550043 105943477
SETR: 125994861 125994862 125994864 126033411 126033848
LAV: 100666635 100675653 100676133 100676880
TMU: 101340781 101346446 101346874 101350013 101350258
ETF: 101650213 101650523 101655109 101655637 101655958
DNM: 101414777 101433008 101433204 101434138 101434218 101435423 101436676 101437101 101437727
MDO: 100020348 100023149 100023204 100023235 100026569 100026598 100026618 100026637 100028608
GAS: 123232993 123233004 123233006 123236366 123236629 123238227 123238228 123238230 123238233 123238234 123238235 123238257
SHR: 100915447 100918856 100919120 100920607 100927632 100928062 100933015 100933766
AFZ: 127551720 127551721 127551783 127552019 127552033 127552034
PCW: 110192769 110200600 110200601 110213986 110215468
TVP: 118828026 118828039 118828040 118828042 118828043 118828044 118828045 118828046 118828051 118828056 118828058 118828060 118828118 118828175 118828284 118828583 118828771 118828830 118830249 118830250 118859159
GGA: 100858007(RP11-400G3.5) 414833(CYP2C45)
PCOC: 116234486
MGP: 100544448
CJO: 107315788
TPAI: 128077571 128077572 128077573
LMUT: 125694067 125694068 125694069 125694070 125694071
NMEL: 110399446
APLA: 101797318 101805432 113844003
ACYG: 106034197 106046725
CATA: 118243351 118255579
AFUL: 116491444 116491640 116491641 116491642 116496669
TGU: 100219254 100228872
LSR: 110475152 110480306
SCAN: 103813978 103819903
PMOA: 120499733
OTC: 121338316 121341821
PRUF: 121354193 121357631
GFR: 102041497 102043152
FAB: 101806491 101815619
OMA: 130255070 130260372
PHI: 102100933 102107291
PMAJ: 107207028 107212622
CCAE: 111931097 111937179
CCW: 104695623 104697085
CBRC: 103613784 103624459
ETL: 114065370
ZAB: 102067353 102073503 102074741
ZLE: 135449336 135455550 135460995
ACHL: 103805798
SVG: 106855352 106862297
MMEA: 130581013
HRT: 120748109
SATI: 136364239 136369197 136369528
FPG: 101913238 101916760
FCH: 102048002 102059256
CCRI: 104159509 104168852
NNT: 104399782 104405230
SHAB: 115608667 115608730 115608831 115616648
ACUN: 113481765 113486792
TALA: 104360444 104363792
ACHC: 115341565 115348476
HALD: 104315668
HLE: 104831888
AGEN: 126042554 126043766
GCL: 127017485 127023938
CSTI: 104561375
LDI: 104343172 104353803
MNB: 103771400
DPUB: 104297684 104301981
AVIT: 104273142
BRHI: 104492082
EGZ: 104125355 104129118
NNI: 104010978 104018935
PCRI: 104034656 104037972
PCAO: 104045589 104049798
PADL: 103915567 103918695
AFOR: 103897610 103903595
FGA: 104073873 104081578
GSTE: 104260632 104264065
CLV: 102087915 102098038
MUI: 104534424
PGUU: 104461775 104467274
PLET: 104623081 104626155
EHS: 104504230 104516609
CMAC: 104476783
CUCA: 104060040 104060777 104067911
TEO: 104374656
BREG: 104630155 104637583
OHA: 104329922
ACAR: 104529274
CPEA: 104391477 104398212
CVF: 104281946 104289750
RTD: 128911029 128911351 128911515 128911560 128911561 128917900
AAM: 106498947 106499405
AROW: 112961017 112970877
NPD: 112950986 112956875
TGT: 104566795
DNE: 112980237 112995565
SCAM: 104141787 104143382
ASN: 102372575 102385966 102386218
AMJ: 102572949 102573559 102573618
CPOO: 109315166
GGN: 109287335 109287406
CMY: 102931882
CCAY: 125621101
DCC: 119842814 119847395
CPIC: 101945572 101950120
TST: 117887460 117888580 117888938
CABI: 116822417 116822898
MRV: 120382954 120388953
ACS: 100552964 100554667 100560019 100561903 100562097 100562300 100562499 100565059
ASAO: 132761864 132761881 132763575 132764077 132768594 132769293 132780888 132781058 132781361 132781421 132781507 132781595 132781659 132781729
PVT: 110070438 110084010 110090724
SUND: 121915628 121918763 121918778 121918807 121927308 121927315
PBI: 103054127 103067414
PMUR: 107286792 107296151
CTIG: 120296915 120298505 120298506 120317803
TSR: 106538299
PGUT: 117659140
APRI: 131190555 131190557
PTEX: 113435173 113437257
NSS: 113414159 113426274
VKO: 123035026 123035029
PMUA: 114590635 114590640 114590645 114590724 114590725 114590727 114590728
PRAF: 128407548 128407555 128407562 128407576 128407585 128407593 128407603 128407604 128408551
ZVI: 118079426 118079919 118079920 118079922 118080863 118080874
HCG: 128343349
EMC: 129324116
XLA: 108699286 379297(cyp2a6.1.S) 444542(cyp2c8.2.L)
XTR: 448236(cyp2c8.2)
NPR: 108800780
RTEM: 120913341 120936065 120936220
BBUF: 120978128 121009418
BGAR: 122923772 122923881 122940043 122941761 122945938 122946510
CPLA: 122542870
HOC: 132836798
LERI: 129714142 129714143
LRJ: 133341215 133341226
BFO: 118416246
BBEL: 109470437
SCLV: 120338348 120339246 120345724 120346076
MNZ: 135219059
HAZT: 108665260
DSV: 119449464 119459204
RSAN: 119373421
PMEO: 129596816 129596855
HRF: 124113633
HRJ: 124262364 124281202 124291019
CRG: 105333836
CANU: 128179353
CVN: 111099468 111099985 111137423
RPHI: 132743744
OSN: 115231110
LJP: 135468420 135468424
AG: AAC08738(CYP2C41) BAA02001(CYP2C26) BAA02002(CYP2C27) BAA02003(CYP2C28) CAA44753(CYP2C25)
 » show all
Reference
PMID:2831965 (CYP2C2)
  Authors
Imai Y, Komori M, Sato R
  Title
Comparison of primary structures deduced from cDNA nucleotide sequences for various forms of liver microsomal cytochrome P-450 from phenobarbital-treated rabbits.
  Journal
Biochemistry 27:80-8 (1988)
DOI:10.1021/bi00401a014
  Sequence
[ocu:100328924]
Reference
PMID:3335521 (CYP2C7)
  Authors
Kimura H, Yoshioka H, Sogawa K, Sakai Y, Fujii-Kuriyama Y
  Title
Complementary DNA cloning of cytochrome P-450s related to P-450(M-1) from the complementary DNA library of female rat livers. Predicted primary structures for  P-450f, PB-1, and PB-1-related protein with a bizarre replacement block and their mode of transcriptional expression.
  Journal
J Biol Chem 263:701-7 (1988)
  Sequence
[rno:29298]
Reference
PMID:8611037 (CYP2C11)
  Authors
Biagini C, Celier C
  Title
cDNA-directed expression of two allelic variants of cytochrome P450 2C11 using COS1 and SF21 insect cells.
  Journal
Arch Biochem Biophys 326:298-305 (1996)
DOI:10.1006/abbi.1996.0079
  Sequence
[rno:29277]
Reference
PMID:2820951 (CYP2C14)
  Authors
Imai Y
  Title
Cytochrome P-450 related to P-4504 from phenobarbital-treated rabbit liver: molecular cloning of cDNA and characterization of cytochrome P-450 obtained by its expression in yeast cells.
  Journal
J Biochem 101:1129-39 (1987)
DOI:10.1093/oxfordjournals.jbchem.a121977
  Sequence
[ocu:100328936]
Reference
PMID:2263487 (CYP2C23)
  Authors
Cook EA, Groenewegen WA, Gloger IS, Piggott JR, Suckling KE, Wolf CR
  Title
cDNA and deduced amino acid sequence of a novel cytochrome P-450 from female rat liver mRNA with high homology to P-450 IIC family.
  Journal
Nucleic Acids Res 18:7156 (1990)
DOI:10.1093/nar/18.23.7156
  Sequence
[rno:83790]
Reference
PMID:8114672 (CYP2C25 CYP2C26 CYP2C27)
  Authors
Sakuma T, Masaki K, Itoh S, Yokoi T, Kamataki T
  Title
Sex-related differences in the expression of cytochrome P450 in hamsters: cDNA cloning and examination of the expression of three distinct CYP2C cDNAs.
  Journal
Mol Pharmacol 45:228-36 (1994)
  Sequence
[ag:CAA44753 BAA02001 BAA02002]
Reference
PMID:7771794 (CYP2C28)
  Authors
Sakuma T, Yokoi T, Kamataki T
  Title
Isolation and characterization of a new cDNA clone belonging to the cytochrome P450 2C gene subfamily in hamsters.
  Journal
Arch Biochem Biophys 319:267-73 (1995)
DOI:10.1006/abbi.1995.1291
  Sequence
[ag:BAA02003]
Reference
PMID:8130255 (CYP2C29)
  Authors
Matsunaga T, Watanabe K, Yamamoto I, Negishi M, Gonzalez FJ, Yoshimura H
  Title
cDNA cloning and sequence of CYP2C29 encoding P-450 MUT-2, a microsomal aldehyde oxygenase.
  Journal
Biochim Biophys Acta 1184:299-301 (1994)
DOI:10.1016/0005-2728(94)90237-2
  Sequence
[mmu:13095]
Reference
PMID:9721182 (CYP2C37)
  Authors
Luo G, Zeldin DC, Blaisdell JA, Hodgson E, Goldstein JA
  Title
Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid.
  Journal
Arch Biochem Biophys 357:45-57 (1998)
DOI:10.1006/abbi.1998.0806
  Sequence
[mmu:13096]
Reference
PMID:9492393 (CYP2C41)
  Authors
Blaisdell J, Goldstein JA, Bai SA
  Title
Isolation of a new canine cytochrome P450 CDNA from the cytochrome P450 2C subfamily (CYP2C41) and evidence for polymorphic differences in its expression.
  Journal
Drug Metab Dispos 26:278-83 (1998)
  Sequence
[ag:AAC08738]
Reference
PMID:15102943 (CYP2C50)
  Authors
Wang H, Zhao Y, Bradbury JA, Graves JP, Foley J, Blaisdell JA, Goldstein JA, Zeldin DC
  Title
Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities.
  Journal
Mol Pharmacol 65:1148-58 (2004)
DOI:10.1124/mol.65.5.1148
  Sequence
[mmu:107141]
Reference
PMID:2263625 (CYP2C70)
  Authors
Emi Y, Chijiiwa C, Omura T
  Title
A different cytochrome P450 form is induced in primary cultures of rat hepatocytes.
  Journal
Proc Natl Acad Sci U S A 87:9746-50 (1990)
DOI:10.1073/pnas.87.24.9746
  Sequence
[rno:171518]

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