KEGG   ORTHOLOGY: K07410
Entry
K07410                      KO                                     
Symbol
CYP1B1
Name
cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00380  Tryptophan metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map04913  Ovarian steroidogenesis
map05204  Chemical carcinogenesis - DNA adducts
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
Disease
H01159  Anterior segment dysgenesis
H01203  Primary congenital glaucoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
   05204 Chemical carcinogenesis - DNA adducts
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
   05207 Chemical carcinogenesis - receptor activation
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
   05208 Chemical carcinogenesis - reactive oxygen species
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07410  CYP1B1; cytochrome P450 family 1 subfamily B1
Other DBs
RN: R03088 R03090 R03629 R07079 R07080 R07081 R07085 R07087 R09416 R09418 R09442
Genes
HSA: 1545(CYP1B1)
PTR: 459163(CYP1B1)
PPS: 100989599(CYP1B1)
GGO: 101134278
PON: 100172192(CYP1B1)
NLE: 100583040
MCC: 710385(CYP1B1)
MCF: 102146810(CYP1B1)
MTHB: 126933548
CSAB: 103220462(CYP1B1)
CATY: 105597190
PANU: 101014578
TGE: 112637014
RRO: 104680972
RBB: 108520884
TFN: 117062450
PTEH: 111545371
CJC: 100395270(CYP1B1)
SBQ: 101049264
CSYR: 103271895
MMUR: 105884508
LCAT: 123636812
OGA: 100949593
MMU: 13078(Cyp1b1)
MCAL: 110312728
MPAH: 110335735
RNO: 25426(Cyp1b1)
MCOC: 116079592
MUN: 110547086
CGE: 100759241
MAUA: 101839568
PLEU: 114683578
MORG: 121432953
MFOT: 126514555
AAMP: 119807802
NGI: 103725278
HGL: 101701066
CPOC: 100719054
CCAN: 109685237
DORD: 105986861
DSP: 122104563
NCAR: 124962692
OCU: 100358590
OPI: 101531725
TUP: 102492978
GVR: 103600797
CFA: 483038(CYP1B1)
CLUD: 112664509
VVP: 112935290
VLG: 121491956
AML: 100466967
UMR: 103671894
UAH: 113241453
UAR: 123799824
LLV: 125109142
MPUF: 101676151
ORO: 101365942
EJU: 114219641
ZCA: 113937594
MLX: 118007783
NSU: 110587203
LWW: 102734979
FCA: 101099873
PYU: 121044356
PBG: 122497249
LRUF: 124502968
PTG: 102950579
PPAD: 109265731
AJU: 106978960
HHV: 120244637
BTA: 511470(CYP1B1)
BOM: 102283377
BIU: 109565990
BBUB: 102406111
BBIS: 104999966
CHX: 102184252
OAS: 101119706
ODA: 120851684
CCAD: 122441577
SSC: 100625479
CFR: 102510682
CBAI: 105078974
CDK: 105103641
VPC: 102527799
BACU: 103004066
LVE: 103083349
OOR: 101289532
DLE: 111174870
PCAD: 102981351
PSIU: 116764271
ECB: 100070088(CYP1B1)
EPZ: 103548412
EAI: 106825888
MYB: 102251701
MYD: 102767262
MMYO: 118669092
MLF: 102417339
MNA: 107541766
PKL: 118717247
HAI: 109385488
DRO: 112298126
SHON: 119001228
AJM: 119063849
PDIC: 114500131
PHAS: 123811584
MMF: 118631254
RFQ: 117033397
PALE: 102885732
PGIG: 120621764
PVP: 105292959
RAY: 107519646
MJV: 108387118
TOD: 119259388
SARA: 101541021
LAV: 100655003
TMU: 101340605
ETF: 101642387
DNM: 101414120
MDO: 100011610
GAS: 123234682
SHR: 100935353
PCW: 110201392
OAA: 100079784(CYP1B1)
GGA: 421466(CYP1B1)
PCOC: 116233159
MGP: 100542888
CJO: 107311343
NMEL: 110396658
APLA: 101797494
ACYG: 106029463
AFUL: 116488292
TGU: 100230258
LSR: 110469414
SCAN: 103821707
PMOA: 120506903
OTC: 121335862
PRUF: 121358603
FAB: 101808257
PHI: 102104659
PMAJ: 107202509
CCW: 104684373
CBRC: 103624139
ETL: 114065190
ZAB: 102068269
FPG: 101910938
FCH: 102051876
CLV: 102085752
EGZ: 104124112
NNI: 104018708
ACUN: 113478680
TALA: 104365716
PADL: 103922881
AFOR: 103902731
ACHC: 115350101
HLE: 104840371
AGEN: 126051773
GCL: 127015235
DPUB: 104310306
CPEA: 104394945
CUCA: 104057920
AAM: 106485484
AROW: 112973407
NPD: 112957572
DNE: 112984647
AMJ: 102560255(CYP1B1)
CPOO: 109319889
GGN: 109304747
PSS: 102451045
CMY: 114019062
CPIC: 101941680
TST: 117874620
CABI: 116822556
MRV: 120400195
ACS: 100561291
PVT: 110083935
SUND: 121924964
PBI: 103059588
PMUR: 107287481
CTIG: 120312077
TSR: 106557416
PGUT: 117671886
VKO: 123033875
PMUA: 114594484
ZVI: 118082704
GJA: 107120817
STOW: 125426126
XLA: 108716653(cyp1b1.L) 108717803(cyp1b1.S)
XTR: 100490477(cyp1b1)
RTEM: 120937478
BBUF: 120998783
BGAR: 122934643
DRE: 100150054(cyp1b1)
PPRM: 120468625
MAMB: 125277247
IPU: 100313516(cyp1b)
PHYP: 113545523
SMEO: 124378272
TFD: 113661120
AMEX: 103036816
EEE: 113579900
TRU: 101073188
LCO: 104921916
CGOB: 115020443
ELY: 117248681
EFO: 125903589
PLEP: 121954937
SLUC: 116047866
ECRA: 117960939
ESP: 116705258
PFLV: 114571967
GAT: 120820387
PPUG: 119214523
MSAM: 119916912
CUD: 121510615
ALAT: 119034148
MZE: 101487279
ONL: 100653403(cyp1b1)
OAU: 116318802
OLA: 101159216
OML: 112140813
XMA: 102221787
XCO: 114138595
XHE: 116713268
PRET: 103477101
PFOR: 103148258
PLAI: 106951802
PMEI: 106920957
GAF: 122842251
CVG: 107088618
CTUL: 119782895
GMU: 124858669
NFU: 107375515
KMR: 108247157
ALIM: 106525583
NWH: 119410756
AOCE: 111586556
MCEP: 125019270
CSEM: 103387492
POV: 109629221
SSEN: 122781479
HHIP: 117775246
HSP: 118119456
LCF: 108886282
SDU: 111220624
SLAL: 111669388
XGL: 120796037
HCQ: 109523136
MALB: 109962476
BSPL: 114842071
OMY: 100381269(cyp1b1) 110502297
OGO: 124041418
ELS: 105029712
SFM: 108925836
PKI: 111849531
AANG: 118218479
LOC: 102695612
PSEX: 120516625
LCM: 102362765
CMK: 103178928
RTP: 109922910
CRG: 105345597
 » show all
Reference
PMID:8175734
  Authors
Sutter TR, Tang YM, Hayes CL, Wo YY, Jabs EW, Li X, Yin H, Cody CW, Greenlee WF
  Title
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2.
  Journal
J Biol Chem 269:13092-9 (1994)
DOI:10.1016/S0021-9258(17)36803-5
  Sequence
[hsa:1545]

KEGG   ORTHOLOGY: K07408
Entry
K07408                      KO                                     
Symbol
CYP1A1
Name
cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
Pathway
map00140  Steroid hormone biosynthesis
map00380  Tryptophan metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map01100  Metabolic pathways
map04913  Ovarian steroidogenesis
map05204  Chemical carcinogenesis - DNA adducts
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05207 Chemical carcinogenesis - receptor activation
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
   05208 Chemical carcinogenesis - reactive oxygen species
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1  unspecific monooxygenase
     K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP1 family
   K07408  CYP1A1; cytochrome P450 family 1 subfamily A1
Other DBs
RN: R02354 R02355 R03089 R03408 R03629 R07000 R07001 R07021 R07022 R07079 R07080 R07081 R07085 R07087 R07098 R07099 R08390 R08392 R09418 R09423 R09442
Genes
HSA: 1543(CYP1A1)
PTR: 453744(CYP1A1)
PPS: 100976184(CYP1A1)
GGO: 101129522
PON: 100457153
NLE: 100585507
MCC: 678694(CYP1A1)
MCF: 102129994(CYP1A1)
MTHB: 126960000
CSAB: 103245331(CYP1A1)
CATY: 105600061
PANU: 101001307
TGE: 112627760
RRO: 104672151
RBB: 108531476
TFN: 117070364
PTEH: 111529702
CJC: 100393083(CYP1A1)
SBQ: 101038217
CSYR: 103271646
MMUR: 105854864
LCAT: 123624369
OGA: 100955410
MMU: 13076(Cyp1a1)
MCAL: 110301270
MPAH: 110328033
RNO: 24296(Cyp1a1)
MCOC: 116071961
MUN: 110558545
CGE: 100751269
MAUA: 101844540
PLEU: 114690337
MORG: 121445349
MFOT: 126507531
AAMP: 119808952
NGI: 103736921
HGL: 101707509
CPOC: 100135512(Cyp1a1)
CCAN: 109701505
DORD: 105982352
DSP: 122098438
NCAR: 124977051
OCU: 100328613
OPI: 101533768
TUP: 102484009
GVR: 103588057
CFA: 100686778(CYP1A1)
CLUD: 112675585
VVP: 112908776
VLG: 121484958
AML: 100473028
UMR: 103678992
UAH: 113240972
UAR: 123790682
ELK: 111153267
LLV: 125105138
MPUF: 101676222
ORO: 101382250
EJU: 114206471
ZCA: 113910089
MLX: 118003748
NSU: 110583893
LWW: 102739666
FCA: 554347(CYP1A1)
PYU: 121041992
PBG: 122468425
LRUF: 124508019
PTG: 102966263
PPAD: 109262691
AJU: 106979443
HHV: 120235772
BTA: 282870(CYP1A1)
BOM: 102283235
BIU: 109575587
BBUB: 102399021
BBIS: 104990991
CHX: 102170823
OAS: 100170113(CYP1A1)
ODA: 120875451
CCAD: 122419730
SSC: 403103(CYP1A1)
CFR: 102518111
CBAI: 105069192
CDK: 105087262
VPC: 102530468
BACU: 103008057
LVE: 103071513
OOR: 101287158
DLE: 111177818
PCAD: 102984326
PSIU: 116749907
ECB: 100062285(CYP1A1)
EPZ: 103552317
EAI: 106831264
MYB: 102262349
MYD: 102762200
MMYO: 118675915
MLF: 102437172
MNA: 107535216
PKL: 118728867
HAI: 109396247
DRO: 112301821
SHON: 118987754
PDIC: 114492343
PHAS: 123825280
MMF: 118643668
RFQ: 117024155
PALE: 102892046
PGIG: 120597850
PVP: 105306836
RAY: 107510533
MJV: 108388606
TOD: 119237890
SARA: 101550604
LAV: 100665901
TMU: 101359275
ETF: 101661225
DNM: 101423437
MDO: 100029871
GAS: 123232970
SHR: 100927711
PCW: 110213927
OAA: 100080942(CYP1A1)
ZVI: 118084457
STOW: 125424760
BBEL: 109480286
GAE: 121368990
CRG: 105329067
 » show all
Reference
PMID:2989797
  Authors
Jaiswal AK, Gonzalez FJ, Nebert DW
  Title
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism.
  Journal
Nucleic Acids Res 13:4503-20 (1985)
DOI:10.1093/nar/13.12.4503
  Sequence
[hsa:1543]
Reference
PMID:3019683
  Authors
Kawajiri K, Watanabe J, Gotoh O, Tagashira Y, Sogawa K, Fujii-Kuriyama Y
  Title
Structure and drug inducibility of the human cytochrome P-450c gene.
  Journal
Eur J Biochem 159:219-25 (1986)
DOI:10.1111/j.1432-1033.1986.tb09857.x
  Sequence
[hsa:1543]

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