KEGG ORTHOLOGY: K07593

ORTHOLOGY: K07593

Entry

K07593                      KO

Symbol

SLC2A2, GLUT2

Name

MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2

Pathway

map04911

Insulin secretion

map04917

Prolactin signaling pathway

map04922

Glucagon signaling pathway

map04930

Type II diabetes mellitus

map04931

Insulin resistance

map04950

Maturity onset diabetes of the young

map04973

Carbohydrate digestion and absorption

map05230

Central carbon metabolism in cancer

Disease

H00069

Glycogen storage disease

H01947

Fanconi-Bickel syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04922 Glucagon signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04917 Prolactin signaling pathway
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04950 Maturity onset diabetes of the young
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
   04931 Insulin resistance
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC2: Facilitative GLUT transporter
   K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
Major facilitator superfamily (MFS)
  Sugar transporters
   Sugar porter (SP) family
    K07593  SLC2A2, GLUT2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2

Other DBs

GO:

0005355

TC:	2.A.1.1.29

Genes

HSA:	6514(SLC2A2)

PTR:	460848(SLC2A2)

PPS:	100983878(SLC2A2)

GGO:	101126141(SLC2A2)

PON:	100437366(SLC2A2)

PPYG:

129032476(SLC2A2)

NLE:	100603133(SLC2A2)

HMH:	116480104(SLC2A2)

SSYN:

134733057(SLC2A2)

MCC:	695538(SLC2A2)

MCF:	102130700(SLC2A2)

MTHB:

126948355

MNI:	105465712(SLC2A2)

CSAB:

103221255(SLC2A2)

CATY:

105586069(SLC2A2)

PANU:

101022043(SLC2A2)

TGE:	112618751(SLC2A2)

MLEU:

105552594(SLC2A2)

RRO:	104660535(SLC2A2)

RBB:	108515004(SLC2A2)

TFN:	117083729(SLC2A2)

PTEH:

111543526(SLC2A2)

CANG:

105516713(SLC2A2)

CJC:	100397713(SLC2A2)

SBQ:	101053596(SLC2A2)

CIMI:

108305288(SLC2A2)

ANAN:

105727033

CSYR:

103260645(SLC2A2)

MMUR:

105855416(SLC2A2)

LCAT:

123630261(SLC2A2)

PCOQ:

105806978(SLC2A2)

OGA:	100955667(SLC2A2)

MMU:	20526(Slc2a2)

MCAL:

110291094(Slc2a2)

MPAH:

110320473(Slc2a2)

RNO:	25351(Slc2a2)

MCOC:

116095027(Slc2a2)

ANU:	117707535(Slc2a2)

MUN:	110545687(Slc2a2)

CGE:	100750908(Slc2a2)

MAUA:

101827043(Slc2a2)

PROB:

127223358(Slc2a2)

PLEU:

114697557(Slc2a2)

MORG:

121452876(Slc2a2)

MFOT:

126501434

AAMP:

119826881(Slc2a2)

NGI:	103731696(Slc2a2)

HGL:	101699012(Slc2a2)

CPOC:

100733937(Slc2a2)

CCAN:

109682261(Slc2a2)

DORD:

105985578(Slc2a2)

DSP:	122107286(Slc2a2)

PLOP:

125351982(Slc2a2)

NCAR:

124992591

MMMA:

107149487(Slc2a2)

OCU:

100338918

OPI:	101533428(SLC2A2)

TUP:	102497006(SLC2A2)

GVR:	103603569(SLC2A2)

CFA:	488165(SLC2A2)

CLUD:

112645960(SLC2A2)

VVP:	112926672(SLC2A2)

VLG:	121477379(SLC2A2)

NPO:	129498925(SLC2A2)

AML:	100475889(SLC2A2)

UMR:	103676147(SLC2A2)

UAH:	113255119(SLC2A2)

UAR:	123786389(SLC2A2)

ELK:

111150341

LLV:

125100360

MPUF:

101670937(SLC2A2)

MNP:	132012050(SLC2A2)

MLK:	131824869(SLC2A2)

NVS:	122908694(SLC2A2)

ORO:	101367009(SLC2A2)

EJU:	114207055(SLC2A2)

ZCA:	113918857(SLC2A2)

MLX:	118000275(SLC2A2)

NSU:	110591670(SLC2A2)

LWW:	102746940(SLC2A2)

FCA:	100142681(SLC2A2)

PYU:	121033988(SLC2A2)

PCOO:

112849531(SLC2A2)

PBG:	122491735(SLC2A2)

PVIV:

125175219(SLC2A2)

LRUF:

124526881

PTG:	102961271(SLC2A2)

PPAD:

109275126(SLC2A2)

PUC:

125921604

AJU:

106990050

HHV:	120234618(SLC2A2)

BTA:	282357(SLC2A2)

BOM:	102277237(SLC2A2)

BIU:	109558192(SLC2A2)

BBUB:

102400959(SLC2A2)

BBIS:

104985196(SLC2A2)

CHX:	102176460(SLC2A2)

OAS:	443205(SLC2A2)

BTAX:

128050075(SLC2A2)

ODA:	120869759(SLC2A2)

CCAD:

122444940(SLC2A2)

MBEZ:

129551715(SLC2A2)

SSC:	397429(SLC2A2)

CFR:	102524363(SLC2A2)

CBAI:

105063293(SLC2A2)

CDK:	105086009(SLC2A2)

VPC:	102540787(SLC2A2)

BACU:

103000646(SLC2A2)

BMUS:

118894611(SLC2A2)

LVE:	103086850(SLC2A2)

OOR:	101285939(SLC2A2)

DLE:	111174077(SLC2A2)

PCAD:

102984344(SLC2A2)

PSIU:

116753535(SLC2A2)

NASI:

112392358(SLC2A2)

ECB:	100033974(SLC2A2)

EPZ:	103546363(SLC2A2)

EAI:	106847542(SLC2A2)

MYB:	102257921(SLC2A2)

MYD:	102773357(SLC2A2)

MMYO:

118677395(SLC2A2)

MLF:	102417181(SLC2A2)

MDT:	132230104(SLC2A2)

PKL:	118723607(SLC2A2)

EFUS:

103286732(SLC2A2)

MNA:	107529525(SLC2A2)

DRO:	112304870(SLC2A2)

SHON:

118987406(SLC2A2)

AJM:	119043438(SLC2A2)

PDIC:

114515126(SLC2A2)

PHAS:

123827541(SLC2A2)

MMF:	118617351(SLC2A2)

PPAM:

129076313(SLC2A2)

HAI:	109383439(SLC2A2)

RFQ:	117012522(SLC2A2)

PALE:

102883555(SLC2A2)

PGIG:

120604383(SLC2A2)

PVP:	105305684(SLC2A2)

RAY:	107501411(SLC2A2)

MJV:	108398018(SLC2A2)

TOD:	119257284(SLC2A2)

SARA:

101557379(SLC2A2)

SETR:

126011766(SLC2A2)

LAV:	100669209(SLC2A2)

TMU:

101356489

ETF:	101656481(SLC2A2)

DNM:	101412484 101415775 101420912 101422600 101426792 101427108 101433314 101435288 101439289 101441311 101442210 101443104 101443849 101444965 101447085

MDO:	100010342(SLC2A2)

GAS:	123242829(SLC2A2)

SHR:	100923865(SLC2A2)

AFZ:

127552868

PCW:	110203994(SLC2A2)

TVP:	118846080(SLC2A2)

OAA:	100086793(SLC2A2)

GGA:	396272(SLC2A2)

PCOC:

116243383(SLC2A2)

MGP:	100539563(SLC2A2)

CJO:	107318334(SLC2A2)

TPAI:

128081716(SLC2A2)

LMUT:

125697540(SLC2A2)

NMEL:

110398099(SLC2A2)

APLA:

101803907(SLC2A2)

ACYG:

106031994(SLC2A2)

CATA:

118253191(SLC2A2)

AFUL:

116492598(SLC2A2)

TGU:	100218276(SLC2A2)

LSR:	110480353(SLC2A2)

SCAN:

103815293(SLC2A2)

PMOA:

120504366(SLC2A2)

OTC:	121336562(SLC2A2)

PRUF:

121353718(SLC2A2)

GFR:	102038277(SLC2A2)

FAB:	101820821(SLC2A2)

OMA:	130256943(SLC2A2)

PHI:	102102379(SLC2A2)

PMAJ:

107208774(SLC2A2)

CCAE:

111933593(SLC2A2)

CCW:	104688041(SLC2A2)

CBRC:

103625083(SLC2A2)

ETL:	114061180(SLC2A2)

ZAB:	102066121(SLC2A2)

ZLE:	135451546(SLC2A2)

ACHL:

103806555(SLC2A2)

SVG:	106859654(SLC2A2)

MMEA:

130575480(SLC2A2)

HRT:	120757031(SLC2A2)

SATI:

136365358(SLC2A2)

FPG:	101924748(SLC2A2)

FCH:	102053009(SLC2A2)

CCRI:

104155807(SLC2A2)

NNT:	104401734(SLC2A2)

SHAB:

115611833(SLC2A2)

ACUN:

113483593(SLC2A2)

TALA:

104359800(SLC2A2)

ACHC:

115347487(SLC2A2)

HALD:

104320291(SLC2A2)

HLE:	104835090(SLC2A2)

AGEN:

126040009

GCL:

127020088

CSTI:

104555200

LDI:	104349865(SLC2A2)

MNB:	103774120(SLC2A2)

DPUB:

104301910(SLC2A2)

AVIT:

104270076(SLC2A2)

BRHI:

104495653(SLC2A2)

EGZ:	104132471(SLC2A2)

NNI:	104022055(SLC2A2)

PCRI:

104025213(SLC2A2)

PCAO:

104046935(SLC2A2)

PADL:

103924962(SLC2A2)

AFOR:

103899989(SLC2A2)

FGA:	104072871(SLC2A2)

GSTE:

104262822(SLC2A2)

CLV:	102090795(SLC2A2)

MUI:	104548306(SLC2A2)

PGUU:

104465138(SLC2A2)

PLET:

104625247(SLC2A2)

EHS:	104504089(SLC2A2)

CMAC:

104487066

CUCA:

104061074(SLC2A2)

TEO:	104382473(SLC2A2)

BREG:

104634350(SLC2A2)

OHA:	104334407(SLC2A2)

ACAR:

104521347(SLC2A2)

CPEA:

104396927(SLC2A2)

CVF:	104285924(SLC2A2)

RTD:	128911698(SLC2A2)

AAM:	106486598(SLC2A2)

AROW:

112963921(SLC2A2)

NPD:	112952330(SLC2A2)

TGT:	104569987(SLC2A2)

DNE:	112986486(SLC2A2)

SCAM:

104143319(SLC2A2)

ASN:	102372548(SLC2A2)

AMJ:	102573725(SLC2A2)

CPOO:

109308434(SLC2A2)

GGN:	109287981(SLC2A2)

PSS:

102451172

CMY:	102940285(SLC2A2)

CCAY:

125642960(SLC2A2)

DCC:	119861343(SLC2A2)

CPIC:

101951250(SLC2A2)

TST:	117882596(SLC2A2)

CABI:

116826731(SLC2A2)

MRV:	120372697(SLC2A2)

ACS:	100553701(slc2a2)

ASAO:

132769839(SLC2A2)

PVT:	110079055(SLC2A2)

SUND:

121924669(SLC2A2)

PBI:	103063859(SLC2A2)

PMUR:

107296419(SLC2A2)

CTIG:

120305747(SLC2A2)

PGUT:

117678191(SLC2A2)

APRI:

131200830(SLC2A2)

PTEX:

113439771(SLC2A2)

NSS:	113411401(SLC2A2)

VKO:	123025636(SLC2A2)

PMUA:

114597978(SLC2A2)

PRAF:

128414770(SLC2A2)

ZVI:	118093772(SLC2A2)

HCG:	128348838(SLC2A2)

GJA:	107111899(SLC2A2)

STOW:

125437955(SLC2A2)

EMC:	129331957(SLC2A2)

XLA:	108718098(slc2a2.S) 432042(slc2a2.L)

XTR:	496943(slc2a2)

NPR:	108784826(SLC2A2)

RTEM:

120936748(SLC2A2)

BBUF:

120997886(SLC2A2)

BGAR:

122935854(SLC2A2)

MUO:	115479145(SLC2A2)

GSH:	117367153(SLC2A2)

DRE:	322493(slc2a2)

SRX:	107722632 107732515

SANH:

107680265

SGH:	107550598 107586013

CCAR:

109055433 109055434

CAUA:

113045925 113117284

CGIB:

127950361 128029016

PTET:

122324945(slc2a2)

LROH:

127182956(slc2a2)

OMC:	131521057(slc2a2)

PPRM:

120481840(slc2a2)

RKG:	130076046(slc2a2)

MAMB:

125250265(slc2a2)

CIDE:

127522215

CERY:

137003907(slc2a2)

MASI:

127441525 127442295

TROS:

130554096(slc2a2)

TDW:	130417168(slc2a2)

MANU:

129442235(slc2a2)

IPU:

108278343

IFU:	128621121(slc2a2)

PHYP:

113524403

SMEO:

124394937(slc2a2)

TFD:	113637288(slc2a2)

TVC:	132857807(slc2a2)

TRN:	134334635(slc2a2)

AMEX:

103022443(slc2a2)

CMAO:

118804775(slc2a2)

EEE:	113576487(slc2a2)

CHAR:

105908501(slc2a2)

TRU:	101065501(slc2a2)

TFS:	130540277(slc2a2)

TNG:	GSTEN00012716G001

LCO:

104920046

NCC:

104958942

TBEN:

117493873(slc2a2)

CGOB:

115027616

PGEO:

117468019(slc2a2)

GACU:

117558900(slc2a2)

EMAC:

134881063(slc2a2)

ELY:	117267619(slc2a2)

EFO:	125901457(slc2a2)

PLEP:

121953232(slc2a2)

SLUC:

116057458(slc2a2)

ECRA:

117936006(slc2a2)

ESP:

116670514

PFLV:

114546584(slc2a2)

GAT:	120833405(slc2a2)

PPUG:

119227239(slc2a2)

AFB:	129103121(slc2a2)

CLUM:

117751117(slc2a2)

MSAM:

119910326(slc2a2)

SCHU:

122862218(slc2a2)

CUD:	121526087(slc2a2)

ALAT:

119034379(slc2a2)

MZE:	101482471(slc2a2)

ONL:

100534484

OAU:	116318068(slc2a2)

OLA:	101166670(slc2a2)

OML:	112149193(slc2a2)

CSAI:

133462806(slc2a2)

XMA:	102220025(slc2a2)

XCO:	114133742(slc2a2)

XHE:	116708659(slc2a2)

PRET:

103458415(slc2a2)

PFOR:

103146530(slc2a2)

PLAI:

106951030

PMEI:

106932772(slc2a2)

GAF:	122846519(slc2a2)

PPRL:

129365605(slc2a2)

CVG:	107085104(slc2a2)

CTUL:

119788182(slc2a2)

GMU:	124855282(slc2a2)

NFU:	107392074(slc2a2)

KMR:	108249199(slc2a2)

ALIM:

106534351(slc2a2)

NWH:	119427386(slc2a2)

AOCE:

111569440(slc2a2)

MCEP:

125023228(slc2a2)

CSEM:

103378916(slc2a2)

POV:	109636361(slc2a2)

SSEN:

122783194(slc2a2)

HHIP:

117756586(slc2a2)

HSP:	118116257(slc2a2)

PPLT:

128451238(slc2a2)

SMAU:

118285642(slc2a2)

LCF:

108874900

SDU:

111225928

SLAL:

111665821(slc2a2)

XGL:	120795143(slc2a2)

HCQ:	109517287(slc2a2)

SSCV:

125981020

SBIA:

133513839(slc2a2)

PEE:	133412544(slc2a2)

PTAO:

133488126(slc2a2)

BPEC:

110157356(slc2a2)

MALB:

109969620(slc2a2)

BSPL:

114848972(slc2a2)

SJO:	128374839(slc2a2)

SASA:

106575464 106594064

STRU:

115179805 115196226

OTW:	112239038(slc2a2) 112239991

OMY:	100135945 110527388

OGO:	124008175 124010755

ONE:	115120920 115122446

OKI:	109890372 116352895

OKE:	118380910 118381291

SALP:

112077444 112078878

SNH:	120033239 120033537(slc2a2)

CCLU:

121587446 123490361

ELS:

105019809

SFM:	108935126(slc2a2)

PKI:

111850509

AANG:

118229437(slc2a2)

LOC:	102694631(slc2a2)

PSPA:

121326393(slc2a2)

ARUT:

117416738 117423539

PSEX:

120534077(slc2a2)

LCM:	102359756(SLC2A2)

CMK:	103189327(slc2a2)

RTP:	109928470(slc2a2)

CPLA:

122556118(slc2a2)

HOC:	132821813(slc2a2)

LERI:

129703420(slc2a2)

CFEL:

113367822 113367824

PMEO:

129591868 129591954 129592015 129595820 129595821 129601189

» show all

Reference

PMID:3399500

Authors

Fukumoto H, Seino S, Imura H, Seino Y, Eddy RL, Fukushima Y, Byers MG, Shows TB, Bell GI

Title

Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.

Journal

Proc Natl Acad Sci U S A 85:5434-8 (1988)
DOI:10.1073/pnas.85.15.5434

Sequence

[hsa:6514]

Reference

PMID:18393659

Authors

Kellett GL, Brot-Laroche E, Mace OJ, Leturque A

Title

Sugar absorption in the intestine: the role of GLUT2.

Journal

Annu Rev Nutr 28:35-54 (2008)
DOI:10.1146/annurev.nutr.28.061807.155518

Reference

PMID:18660845

Authors

Zhao FQ, Keating AF

Title

Functional properties and genomics of glucose transporters.

Journal

Curr Genomics 8:113-28 (2007)
DOI:10.2174/138920207780368187

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Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   TC (1)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (895)   
   KEGG GENES (437)   
   KEGG MGENES (114)   
   RefGene (341)   
   OC (3)   
Literature (3)   
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