KEGG ORTHOLOGY: K07594

ORTHOLOGY: K07594

Entry

K07594                      KO

Symbol

IPF1, PDX1

Name

insulin promoter factor 1

Pathway

map04911

Insulin secretion

map04930

Type II diabetes mellitus

map04950

Maturity onset diabetes of the young

Disease

H00410

Maturity onset diabetes of the young (MODY)

H00512

Permanent neonatal diabetes mellitus

H00861

Pancreatic agenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K07594  IPF1, PDX1; insulin promoter factor 1
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K07594  IPF1, PDX1; insulin promoter factor 1
   04950 Maturity onset diabetes of the young
    K07594  IPF1, PDX1; insulin promoter factor 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K07594  IPF1, PDX1; insulin promoter factor 1
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain ANTP: HOXL
    K07594  IPF1, PDX1; insulin promoter factor 1

Genes

HSA:	3651(PDX1)

PTR:	452507(PDX1)

PPS:	100990278(PDX1)

GGO:	101130338(PDX1)

PON:	100453613(PDX1)

NLE:	100588182(PDX1)

HMH:	116466391(PDX1)

MCC:	710936(PDX1)

MCF:	102140063(PDX1)

MTHB:

126940748

MNI:	105490204(PDX1)

CSAB:

103249066(PDX1)

CATY:

105597056(PDX1)

PANU:

101003026(PDX1)

TGE:	112610850(PDX1)

MLEU:

105553808(PDX1)

RRO:	104661713(PDX1)

RBB:	108512909(PDX1)

TFN:	117096549(PDX1)

PTEH:

111534199(PDX1)

CANG:

105523513(PDX1)

CJC:	100404648(PDX1)

SBQ:	101037622(PDX1)

CIMI:

108310468(PDX1)

MMUR:

105858892(PDX1)

LCAT:

123648924(PDX1)

PCOQ:

105814791(PDX1)

OGA:	100947908(PDX1)

MMU:	18609(Pdx1)

MCAL:

110295322(Pdx1)

MPAH:

110313077(Pdx1)

RNO:	29535(Pdx1)

MCOC:

116071025(Pdx1)

ANU:	117698275(Pdx1)

CGE:	100757561(Pdx1)

MAUA:

101841656(Pdx1)

PROB:

127237244(Pdx1)

PLEU:

114699105(Pdx1)

MORG:

121465174(Pdx1)

MFOT:

126513526

AAMP:

119825705(Pdx1)

NGI:	103727237(Pdx1)

HGL:	101715013(Pdx1)

CPOC:

100731776(Pdx1)

CCAN:

109694702(Pdx1)

DORD:

105993887(Pdx1)

DSP:	122112655(Pdx1)

NCAR:

124985883

OCU:

100342588

OPI:	101535161(PDX1)

TUP:	102472105(PDX1)

GVR:	103603767(PDX1)

CFA:	493994(PDX1)

CLUD:

112670098(PDX1)

VVP:	112918561(PDX1)

VLG:	121496566(PDX1)

AML:	100483215(PDX1)

UMR:	103664406(PDX1)

UAH:	113251032(PDX1)

UAR:	123791773(PDX1)

ELK:

111158579

LLV:

125096237

MPUF:

101686550(PDX1)

NVS:	122907820(PDX1)

ORO:	101382101(PDX1)

EJU:	114209299(PDX1)

ZCA:	113920801(PDX1)

MLX:	118009193(PDX1)

NSU:	110570272(PDX1)

LWW:	102741752(PDX1)

FCA:	100240682(PDX1)

PYU:	121012777(PDX1)

PCOO:

112861122(PDX1)

PBG:	122496451(PDX1)

LRUF:

124508511

PTG:	102956133(PDX1)

PPAD:

109266128(PDX1)

PUC:

125934074

AJU:	106985533(PDX1)

HHV:	120246839(PDX1)

BTA:	538927(PDX1)

BOM:	102274393(PDX1)

BIU:	109567147(PDX1)

BBUB:

102401237(PDX1)

BBIS:

104996833(PDX1)

CHX:	108637276(PDX1)

OAS:	100820739(PDX1)

ODA:	120882923(PDX1)

CCAD:

122447467(PDX1)

SSC:	397288(PDX1)

CFR:	102507668(PDX1)

CBAI:

105066247(PDX1)

CDK:	105086580(PDX1)

VPC:	102526624 116283274(PDX1)

BACU:

103017851(PDX1)

LVE:	103081030(PDX1)

OOR:	101278757(PDX1)

DLE:	111175107(PDX1)

PCAD:

102989985(PDX1)

PSIU:

116743189(PDX1)

NASI:

112406627(PDX1)

ECB:	100051336(PDX1)

EPZ:	103562044(PDX1)

EAI:	106832925(PDX1)

MYB:	102243671(PDX1)

MYD:	102760970(PDX1)

MMYO:

118649627(PDX1)

MLF:	102442594(PDX1)

MNA:	107534356(PDX1)

PKL:	118730050(PDX1)

HAI:	109395216(PDX1)

DRO:	112296229(PDX1)

SHON:

118995758(PDX1)

AJM:	119064948(PDX1)

PDIC:

114491135(PDX1)

PHAS:

123822741(PDX1)

MMF:	118624602(PDX1)

RFQ:	117021470(PDX1)

PALE:

102883607(PDX1)

PGIG:

120602498(PDX1)

PVP:	105292100(PDX1)

RAY:	107516508(PDX1)

MJV:	108407450(PDX1)

TOD:	119259705(PDX1)

SARA:

101538332(PDX1)

LAV:	100667513(PDX1)

TMU:

101351262

ETF:	101658620(PDX1)

DNM:	101432986(PDX1)

MDO:	100025125(PDX1)

GAS:	123238867(PDX1)

SHR:	100929652(PDX1)

AFZ:

127554722

PCW:	110215536(PDX1)

OAA:	100090417(PDX1)

GGA:	771348(PDX1)

PCOC:

116244267(PDX1)

MGP:	100542263(PDX1)

CJO:	107308292(PDX1)

NMEL:

110393452(PDX1)

APLA:

101796228(PDX1)

ACYG:

125183842(PDX1)

AFUL:

116501757(PDX1)

TGU:	100218605(PDX1)

LSR:	110476714(PDX1)

SCAN:

103827336(PDX1)

PMOA:

120506676(PDX1)

OTC:	121341981(PDX1)

GFR:	102037927(PDX1)

FAB:	101807541(PDX1)

PHI:	102107696(PDX1)

PMAJ:

107205609(PDX1)

CCAE:

111946115

CCW:	120410453(PDX1)

CBRC:

103613634(PDX1)

ETL:	114067526(PDX1)

SVG:	106855224(PDX1)

FPG:	101922997(PDX1)

FCH:	102057886(PDX1)

CLV:	102092342(PDX1)

NNI:	104023085(PDX1)

TALA:

116959119(PDX1)

PADL:

103920187(PDX1)

AFOR:

103908004(PDX1)

ACHC:

115353422(PDX1)

AGEN:

126048211

GCL:

127028787

LDI:	104345723(PDX1)

OHA:	104332733(PDX1)

SHAB:

115604458(PDX1)

DPUB:

104306116(PDX1)

CUCA:

104064232(PDX1)

BRHI:

104493191(PDX1)

AAM:	106500457(PDX1)

AROW:

112970190(PDX1)

NPD:	112956311(PDX1)

TGT:	104577908(PDX1)

DNE:	112988351(PDX1)

AMJ:	102565849(PDX1)

CPOO:

109305530(PDX1)

GGN:	109302230(PDX1)

PSS:	102460320(PDX1)

CMY:	102932643(PDX1)

CPIC:

101945799(PDX1)

TST:	117871721(PDX1)

CABI:

116816238(PDX1)

MRV:	120383022(PDX1)

ACS:	100555743(pdx1)

PVT:	110076439(PDX1)

SUND:

121926657(PDX1)

PBI:	103057530(PDX1)

PMUR:

107287176(PDX1)

CTIG:

120314084(PDX1)

TSR:	106537871(PDX1)

PGUT:

117663966(PDX1)

VKO:	123029166(PDX1)

PMUA:

114595757(PDX1)

ZVI:	118085313(PDX1)

HCG:	128351364(PDX1)

GJA:	107105447(PDX1)

STOW:

125431276(PDX1)

XLA:	100337610(pdx1.S) 108708702(pdx1.L)

XTR:	100490648(pdx1)

NPR:	108796340(PDX1)

RTEM:

120929201(PDX1)

BBUF:

120994161(PDX1)

BGAR:

122933225(PDX1)

DRE:	30721(pdx1)

SRX:	107705191 107716377

SANH:

CCAR:

CAUA:

CGIB:

PPRM:

120476076(pdx1)

MAMB:

125258254(pdx1)

CIDE:

127506111

MASI:

127409946 127432046 127434570

IPU:	108256703(pdx1) 108257620

PHYP:

113541268(pdx1)

SMEO:

124375471(pdx1) 124376690

TFD:	113642595 113661176(pdx1)

AMEX:

103022002 103024120(pdx1)

EEE:	113576157(pdx1) 113586376

TRU:	101063512(pdx1)

TNG:	GSTEN00023870G001

LCO:	104924955(pdx1)

NCC:	104963144(pdx1)

CGOB:

115025259(pdx1)

ELY:	117264656(pdx1)

EFO:	125881840(pdx1)

PLEP:

121960748(pdx1)

SLUC:

116037965(pdx1)

ECRA:

117938213(pdx1)

ESP:	116672578(pdx1)

PFLV:

114549255(pdx1)

GAT:	120811885(pdx1)

PPUG:

119198890(pdx1)

MSAM:

119887191 119909756(pdx1)

CUD:	121527360(pdx1)

ALAT:

119008432(pdx1)

MZE:	101481425(pdx1)

ONL:	100699915(pdx1)

OAU:	116320651(pdx1)

OLA:	101160115(pdx1)

OML:	112151479(pdx1)

XMA:	102237324(pdx1)

XCO:	114136909(pdx1)

XHE:	116711623(pdx1)

PRET:

103456626(pdx1)

PFOR:

103139736(pdx1)

PLAI:

106937222(pdx1)

PMEI:

106908989(pdx1)

GAF:	122824134(pdx1)

CVG:	107102551(pdx1)

CTUL:

119788914(pdx1)

GMU:	124857694(pdx1)

NFU:	107382869(pdx1)

KMR:	108230306(pdx1)

ALIM:

106513432(pdx1)

NWH:	119426905(pdx1)

AOCE:

111584746(pdx1)

MCEP:

124995441(pdx1)

CSEM:

103377262(pdx1)

POV:	109641778(pdx1)

SSEN:

122765847(pdx1)

HHIP:

117753947(pdx1)

HSP:	118098772(pdx1)

LCF:

108881766

SDU:	111220949(pdx1)

SLAL:

111662947(pdx1)

XGL:	120789684(pdx1)

HCQ:	109514077(pdx1)

SSCV:

125986195

BPEC:

110160885(pdx1)

MALB:

109960129(pdx1)

BSPL:

114854377(pdx1)

SASA:

100286705(pdx1) 106579504(pdx1) 106590452

STRU:

115148779(pdx1) 115158528 115195491

OTW:	112216489(pdx1) 112227704 112251133

OMY:	110489664 110522886 110536558(pdx1)

OGO:	123990410(pdx1) 123997826 124037855 124039130

ONE:	115104495(pdx1) 115108533 115131084 115145492

SALP:

111953214 111973402 111976017

SNH:	120027706 120050976 120054927

CCLU:

121533080 121549472(pdx1) 121569254

ELS:	105011835 105021949(pdx1)

SFM:	108939671(pdx1)

PKI:	111839090(pdx1) 111850066

AANG:

118225268(pdx1)

LOC:	102684838(pdx1) 107077167

PSPA:

121321333(pdx1)

ARUT:

117406655 117972472 117972671

PSEX:

120524492(pdx1) 120528600

LCM:	102345653(PDX1) 102354015

CMK:	103178221 103183250(pdx1)

RTP:	109913637(pdx1) 109927410

CPLA:

122550220 122551154(pdx1)

BFO:

118419641

BBEL:

109470583

CIN:	445683(ipf1)

SCLV:

120333024

SPU:	373527(lox)

APLC:

110988620

SKO:

100371286

HRO:	HELRODRAFT_100536

PCAN:

112559017

BGT:	106067332 106067437

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MCAF:

MMER:

OBI:

OSN:

LAK:

DGT:

XEN:

HMG:

Reference

PMID:11692168

Authors

McKinnon CM, Docherty K

Title

Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.

Journal

Diabetologia 44:1203-14 (2001)
DOI:10.1007/s001250100628

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Disease (3)   
   KEGG DISEASE (3)   
Gene (464)   
   KEGG GENES (365)   
   KEGG MGENES (45)   
   RefGene (52)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (476)   

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