KEGG   ORTHOLOGY: K07758
Entry
K07758                      KO                                     

Name
PDXP
Definition
pyridoxal phosphatase [EC:3.1.3.74]
Pathway
ko00750  Vitamin B6 metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00750 Vitamin B6 metabolism
    K07758  PDXP; pyridoxal phosphatase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K07758  PDXP; pyridoxal phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.74  pyridoxal phosphatase
     K07758  PDXP; pyridoxal phosphatase
Protein phosphatases and associated proteins [BR:ko01009]
 HAD phosphatases
  Other HAD phosphatases
   K07758  PDXP; pyridoxal phosphatase
Other DBs
RN: R00173 R01911 R02494
GO: 0033883
Genes
HSA: 57026(PDXP)
PPS: 103786618(PDXP)
GGO: 115931924(PDXP)
PON: 103888967(PDXP)
MCF: 101865359(PDXP)
CSAB: 103223282(PDXP)
CJC: 100399981(PDXP)
SBQ: 101054290(PDXP)
MMU: 57028(Pdxp)
MCAL: 110310563(Pdxp)
MPAH: 110334906(Pdxp)
RNO: 727679(Pdxp)
MUN: 110558854(Pdxp)
CGE: 100755599(Pdxp)
NGI: 103748608(Pdxp)
HGL: 101719475(Pdxp)
CCAN: 109685677(Pdxp)
OCU: 108176292(PDXP)
TUP: 102469858(PDXP)
CFA: 100688635(PDXP)
VVP: 112929147(PDXP)
AML: 105235510(PDXP)
UMR: 103676541(PDXP)
UAH: 113241802(PDXP)
ORO: 101382844(PDXP)
ELK: 111157494
FCA: 101093872(PDXP)
PTG: 102959923(PDXP)
PPAD: 109265541(PDXP)
AJU: 106981047(PDXP)
BTA: 506308(PDXP)
BOM: 102286951(PDXP)
BIU: 109558621(PDXP)
BBUB: 102391389(PDXP)
CHX: 102180199(PDXP)
OAS: 101123544(PDXP)
SSC: 100623846(PDXP)
CDK: 116156496(PDXP)
BACU: 103003329(PDXP)
LVE: 103073497(PDXP)
OOR: 101272288(PDXP)
ECB: 100630816(PDXP)
EPZ: 103541255
MYB: 102251338 102252377(PDXP)
MYD: 102773967(PDXP)
MNA: 107545076(PDXP)
HAI: 109394527(PDXP)
DRO: 112322013(PDXP)
PALE: 102883992(PDXP)
RAY: 107519284(PDXP)
MJV: 108392676(PDXP)
TMU: 101357957
MDO: 100025700(PDXP)
SHR: 100924589(PDXP)
PCW: 110205758(PDXP)
OAA: 100091800(PDXP)
GGA: 771207(PDXP)
MGP: 100539695(PDXP)
CJO: 107313943(PDXP)
NMEL: 110393065(PDXP)
ACYG: 106035787(PDXP)
TGU: 101234251(PDXP)
LSR: 110483791(PDXP)
SCAN: 103813599(PDXP)
GFR: 102033327(PDXP)
FAB: 101809714(PDXP)
PHI: 102108764(PDXP)
PMAJ: 107204187(PDXP)
CCAE: 111935173(PDXP)
CCW: 104696513(PDXP)
ETL: 114055402(PDXP)
FPG: 106112195(PDXP)
FCH: 106631635(PDXP)
CLV: 102098989(PDXP)
ACUN: 113487950(PDXP)
AAM: 106488247(PDXP)
ASN: 102376120(PDXP)
AMJ: 102566322(PDXP)
PSS: 102450474(PDXP)
ACS: 100562224(pdxp)
PVT: 110075983(PDXP)
GJA: 107105933(PDXP)
DRE: 561030(pdxp)
SGH: 107549004
CCAR: 109094314
IPU: 108277379(pdxp)
PHYP: 113544919(pdxp)
AMEX: 103032875(pdxp)
EEE: 113583766(pdxp)
TRU: 101079776(pdxp)
LCO: 104920831(pdxp)
NCC: 104964351(pdxp)
MZE: 101464860(pdxp)
ONL: 100705958(pdxp)
OLA: 101158449(pdxp)
XMA: 102225249(pdxp)
XCO: 114154665
PRET: 103470083(pdxp)
CVG: 107092655(pdxp)
NFU: 107394160(pdxp)
KMR: 108233719(pdxp)
ALIM: 106513663(pdxp)
AOCE: 111564709(pdxp)
POV: 109637080(pdxp)
LCF: 108882065(pdxp)
SDU: 111237762(pdxp)
SLAL: 111651685(pdxp)
HCQ: 109526995(pdxp)
BPEC: 110172127(pdxp)
MALB: 109956628
SASA: 100380361(plpp) 106580405
SFM: 108938493
PKI: 111839313(pdxp)
LCM: 102351909(PDXP)
 » show all
Reference
  Authors
Gohla A, Birkenfeld J, Bokoch GM
  Title
Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics.
  Journal
Nat Cell Biol 7:21-9 (2005)
DOI:10.1038/ncb1201
  Sequence
[hsa:57026]

KEGG   ORTHOLOGY: K13248
Entry
K13248                      KO                                     

Name
PHOSPHO2
Definition
pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74]
Pathway
ko00750  Vitamin B6 metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00750 Vitamin B6 metabolism
    K13248  PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K13248  PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.74  pyridoxal phosphatase
     K13248  PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2
Protein phosphatases and associated proteins [BR:ko01009]
 HAD phosphatases
  Other HAD phosphatases
   K13248  PHOSPHO2; pyridoxal phosphate phosphatase PHOSPHO2
Other DBs
RN: R00173 R01911 R02494
GO: 0033883
Genes
HSA: 493911(PHOSPHO2)
PTR: 459719(PHOSPHO2)
PPS: 103787064(PHOSPHO2)
GGO: 101131418(PHOSPHO2)
PON: 103889977(PHOSPHO2)
NLE: 100582638(PHOSPHO2)
MCC: 100429653(PHOSPHO2)
MCF: 102140894(PHOSPHO2)
CSAB: 103217273(PHOSPHO2)
RRO: 104655044(PHOSPHO2)
RBB: 108516828(PHOSPHO2)
CJC: 100399798(PHOSPHO2)
SBQ: 101028765(PHOSPHO2)
MMU: 73373(Phospho2)
MCAL: 110286120(Phospho2)
MPAH: 110318918(Phospho2)
RNO: 295663(Phospho2)
MUN: 110547783(Phospho2)
CGE: 100764721(Phospho2)
NGI: 103737980(Phospho2) 103741821
HGL: 101722484(Phospho2)
CCAN: 109698018(Phospho2)
TUP: 102479589(PHOSPHO2)
CFA: 100684043(PHOSPHO2)
VVP: 112916429(PHOSPHO2)
AML: 100472338(PHOSPHO2)
UMR: 103659545(PHOSPHO2)
UAH: 113250798(PHOSPHO2)
ORO: 101368120(PHOSPHO2)
ELK: 111141350
FCA: 101087253(PHOSPHO2) 101093877
PTG: 102967832(PHOSPHO2)
AJU: 106987668(PHOSPHO2)
BTA: 507308(PHOSPHO2)
BOM: 102272704(PHOSPHO2)
BIU: 109566749(PHOSPHO2)
BBUB: 102389454(PHOSPHO2)
CHX: 102170186(PHOSPHO2)
OAS: 101119113(PHOSPHO2)
SSC: 100152929(PHOSPHO2)
CFR: 102504844(PHOSPHO2)
CDK: 105091073(PHOSPHO2)
BACU: 103007775(PHOSPHO2)
LVE: 103080288(PHOSPHO2)
OOR: 101285843(PHOSPHO2)
DLE: 111172842(PHOSPHO2)
PCAD: 102985156(PHOSPHO2)
ECB: 100052701(PHOSPHO2)
EPZ: 103554217(PHOSPHO2)
EAI: 106843587(PHOSPHO2)
MYB: 102251449(PHOSPHO2)
MYD: 102752571(PHOSPHO2)
MNA: 107528593(PHOSPHO2)
HAI: 109390417(PHOSPHO2)
DRO: 112322248(PHOSPHO2)
PALE: 102877859(PHOSPHO2)
RAY: 107521050(PHOSPHO2)
MJV: 108409447(PHOSPHO2)
LAV: 100668141(PHOSPHO2)
TMU: 101349620
MDO: 100024396(PHOSPHO2)
SHR: 100922295 116419009(PHOSPHO2)
PCW: 110211551(PHOSPHO2)
GGA: 424160(PHOSPHO2)
MGP: 100542382(PHOSPHO2)
CJO: 107316687(PHOSPHO2)
NMEL: 110400143(PHOSPHO2)
APLA: 101794607(PHOSPHO2)
ACYG: 106029977(PHOSPHO2)
TGU: 100219816(PHOSPHO2)
LSR: 110472775(PHOSPHO2)
SCAN: 103814419(PHOSPHO2)
GFR: 102044333(PHOSPHO2)
FAB: 101815279(PHOSPHO2)
PHI: 102113616(PHOSPHO2)
PMAJ: 107207480(PHOSPHO2)
CCAE: 111932106(PHOSPHO2)
CCW: 104693891(PHOSPHO2)
ETL: 114073767(PHOSPHO2)
FCH: 114014216(PHOSPHO2)
CLV: 102095123(PHOSPHO2)
EGZ: 104128044(PHOSPHO2)
NNI: 104009988(PHOSPHO2)
ACUN: 113481988(PHOSPHO2)
PADL: 103918164(PHOSPHO2)
AAM: 106499198(PHOSPHO2)
ASN: 102382568(PHOSPHO2)
AMJ: 102570726(PHOSPHO2)
PSS: 102450695(PHOSPHO2)
CMY: 102933406(PHOSPHO2)
CPIC: 101950761(PHOSPHO2)
ACS: 100559885(phospho2)
PVT: 110076907(PHOSPHO2)
PBI: 103059635(PHOSPHO2)
PMUR: 107290303(PHOSPHO2)
TSR: 106544265(PHOSPHO2)
PMUA: 114607202(PHOSPHO2)
GJA: 107119693(PHOSPHO2)
XLA: 779316(phospho2.L)
XTR: 493318(phospho2)
NPR: 108785496(PHOSPHO2)
DRE: 799638(phospho2)
SGH: 107582364
IPU: 108271665(phospho2)
PHYP: 113545925(phospho2)
AMEX: 103024835(phospho2)
EEE: 113570300(phospho2)
LCO: 104919874(phospho2)
NCC: 104961275(phospho2)
MZE: 101485115
ONL: 100704477
OLA: 101174256
XMA: 102219566
XCO: 114143791
PRET: 103462227
CVG: 107096031(phospho2)
NFU: 107381999(phospho2)
KMR: 108241596(phospho2)
ALIM: 106534911(phospho2)
AOCE: 111567203(phospho2)
CSEM: 103378978(phospho2)
POV: 109624747(phospho2)
LCF: 108897643(phospho2)
SDU: 111219985
SLAL: 111672261
HCQ: 109513960(phospho2)
BPEC: 110155147(phospho2)
MALB: 109969926(phospho2)
SASA: 100194828(phop2) 106574863
OTW: 112242041(phospho2)
SALP: 112078560(phospho2)
ELS: 105019908
SFM: 108920705(phospho2)
PKI: 111841018(phospho2)
LCM: 102350970(PHOSPHO2)
CMK: 103176439(phospho2)
RTP: 109917160(phospho2)
CIN: 113475804
APLC: 110983821
SKO: 100374642
DME: Dmel_CG12237(CG12237) Dmel_CG14212(CG14212)
DSI: Dsimw501_GD17453(Dsim_GD17453) Dsimw501_GD24455(Dsim_GD24455)
DAN: 6503123
DVI: 6634543
MDE: 101891971
LCQ: 111688580
AAG: 5575050
AME: 725365
BIM: 100740933
BTER: 105666736
CCAL: 108631509
OBB: 114878402
SOC: 105192970
MPHA: 105836592
AEC: 105149951
ACEP: 105621298
PBAR: 105423117
VEM: 105562624
HST: 105186458
DQU: 106745743
CFO: 105248101
LHU: 105679863
PGC: 109853991
OBO: 105283699
PCF: 106787060
MDL: 103569628
TCA: 100141932
DPA: 109534241
ATD: 109605635
NVL: 108561852
BMOR: 101745817
BMAN: 114244171
PMAC: 106710189
PRAP: 110993710
HAW: 110380867
TNL: 113505595
DNX: 107163701
AGS: 114125555
RMD: 113550143
BTAB: 109034019
CLEC: 106670835
PVM: 113815557
CSCU: 111613261
PTEP: 107448827
PCAN: 112564507
CRG: 105338198
MYI: 110442689
OBI: 106883989
NVE: 5521298
EPA: 110254575
ADF: 107355999
AMIL: 114958750
PDAM: 113676502
SPIS: 111330826
DGT: 114524566
AQU: 105312510
ATH: AT1G17710(PEPC1) AT1G73010(PS2) AT4G29530
LJA: Lj0g3v0125959.1(Lj0g3v0125959.1) Lj0g3v0193989.1(Lj0g3v0193989.1) Lj0g3v0319789.1(Lj0g3v0319789.1) Lj3g3v0301740.1(Lj3g3v0301740.1) Lj3g3v0302750.1(Lj3g3v0302750.1) Lj3g3v2693540.1(Lj3g3v2693540.1) Lj3g3v2693540.2(Lj3g3v2693540.2)
SLY: 101246036 101259946(psi14C) 543790(psi14B) 544179(psi14A)
DOSA: Os01t0600500-01(Os01g0600500) Os02t0226200-01(Os02g0226200)
OBR: 102701047
ATS: 109739137(LOC109739137) 109747901(LOC109747901)
ZMA: 100281893(TIDP3606) 100502503 103636051
PPP: 112295379
CNE: CNI03770
CNB: CNBH3600
TASA: A1Q1_02576
ABP: AGABI1DRAFT112429(AGABI1DRAFT_112429)
ABV: AGABI2DRAFT192397(AGABI2DRAFT_192397)
MGL: MGL_1592
MRT: MRET_0683
SMIN: v1.2.000195.t1(symbB.v1.2.000195.t1)
SPAR: SPRG_03461
 » show all
Reference
  Authors
Roberts SJ, Stewart AJ, Schmid R, Blindauer CA, Bond SR, Sadler PJ, Farquharson C
  Title
Probing the substrate specificities of human PHOSPHO1 and PHOSPHO2.
  Journal
Biochim Biophys Acta 1752:73-82 (2005)
DOI:10.1016/j.bbapap.2005.06.009
  Sequence
[hsa:493911]

KEGG   ENZYME: 3.1.3.74
Entry
EC 3.1.3.74                 Enzyme                                 

Name
pyridoxal phosphatase;
vitamine B6 (pyridoxine) phosphatase;
PLP phosphatase;
vitamin B6-phosphate phosphatase;
PNP phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
pyridoxal-5'-phosphate phosphohydrolase
Reaction(IUBMB)
pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate [RN:R00173]
Reaction(KEGG)
R00173;
(other) R01911 R02494
Substrate
pyridoxal 5'-phosphate [CPD:C00018];
H2O [CPD:C00001]
Product
pyridoxal [CPD:C00250];
phosphate [CPD:C00009]
Comment
Requires Mg2+. This enzyme is specific for phosphorylated vitamin B6 compounds: it acts not only on pyridoxal phosphate (PLP), but also on pyridoxine phosphate (PNP), pyridoxamine phosphate (PMP), 4-pyridoxic acid phosphate and 4-deoxypyridoxine phosphate. This reaction can also be carried out by EC 3.1.3.1 (alkaline phosphatase) and EC 3.1.3.2 (acid phosphatase), but these enzymes have very broad substrate specificities.
History
EC 3.1.3.74 created 2004
Pathway
ec00750  Vitamin B6 metabolism
ec01100  Metabolic pathways
Orthology
K07758  pyridoxal phosphatase
K13248  pyridoxal phosphate phosphatase PHOSPHO2
Genes
HSA: 493911(PHOSPHO2) 57026(PDXP)
PTR: 459719(PHOSPHO2)
PPS: 103786618(PDXP) 103787064(PHOSPHO2)
GGO: 101131418(PHOSPHO2) 115931924(PDXP)
PON: 103888967(PDXP) 103889977(PHOSPHO2)
NLE: 100582638(PHOSPHO2)
MCC: 100429653(PHOSPHO2)
MCF: 101865359(PDXP) 102140894(PHOSPHO2)
CSAB: 103217273(PHOSPHO2) 103223282(PDXP)
RRO: 104655044(PHOSPHO2)
RBB: 108516828(PHOSPHO2)
CJC: 100399798(PHOSPHO2) 100399981(PDXP)
SBQ: 101028765(PHOSPHO2) 101054290(PDXP)
MMU: 57028(Pdxp) 73373(Phospho2)
MCAL: 110286120(Phospho2) 110310563(Pdxp)
MPAH: 110318918(Phospho2) 110334906(Pdxp)
RNO: 295663(Phospho2) 727679(Pdxp)
MUN: 110547783(Phospho2) 110558854(Pdxp)
CGE: 100755599(Pdxp) 100764721(Phospho2)
NGI: 103737980(Phospho2) 103741821 103748608(Pdxp)
HGL: 101719475(Pdxp) 101722484(Phospho2)
CCAN: 109685677(Pdxp) 109698018(Phospho2)
OCU: 108176292(PDXP)
TUP: 102469858(PDXP) 102479589(PHOSPHO2)
CFA: 100684043(PHOSPHO2) 100688635(PDXP)
VVP: 112916429(PHOSPHO2) 112929147(PDXP)
AML: 100472338(PHOSPHO2) 105235510(PDXP)
UMR: 103659545(PHOSPHO2) 103676541(PDXP)
UAH: 113241802(PDXP) 113250798(PHOSPHO2)
ORO: 101368120(PHOSPHO2) 101382844(PDXP)
FCA: 101087253(PHOSPHO2) 101093872(PDXP) 101093877
PTG: 102959923(PDXP) 102967832(PHOSPHO2)
PPAD: 109265541(PDXP)
AJU: 106981047(PDXP) 106987668(PHOSPHO2)
BTA: 506308(PDXP) 507308(PHOSPHO2)
BOM: 102272704(PHOSPHO2) 102286951(PDXP)
BIU: 109558621(PDXP) 109566749(PHOSPHO2)
BBUB: 102389454(PHOSPHO2) 102391389(PDXP)
CHX: 102170186(PHOSPHO2) 102180199(PDXP)
OAS: 101119113(PHOSPHO2) 101123544(PDXP)
SSC: 100152929(PHOSPHO2) 100623846(PDXP)
CFR: 102504844(PHOSPHO2)
CDK: 105091073(PHOSPHO2) 116156496(PDXP)
BACU: 103003329(PDXP) 103007775(PHOSPHO2)
LVE: 103073497(PDXP) 103080288(PHOSPHO2)
OOR: 101272288(PDXP) 101285843(PHOSPHO2)
DLE: 111172842(PHOSPHO2)
PCAD: 102985156(PHOSPHO2) 112065875 112065907
ECB: 100052701(PHOSPHO2) 100630816(PDXP)
EPZ: 103541255 103554217(PHOSPHO2)
EAI: 106843587(PHOSPHO2)
MYB: 102251338 102251449(PHOSPHO2) 102252377(PDXP)
MYD: 102752571(PHOSPHO2) 102773967(PDXP)
MNA: 107528593(PHOSPHO2) 107545076(PDXP)
HAI: 109390417(PHOSPHO2) 109394527(PDXP)
DRO: 112322013(PDXP) 112322248(PHOSPHO2)
PALE: 102877859(PHOSPHO2) 102883992(PDXP)
RAY: 107519284(PDXP) 107521050(PHOSPHO2)
MJV: 108392676(PDXP) 108409447(PHOSPHO2)
LAV: 100668141(PHOSPHO2)
MDO: 100024396(PHOSPHO2) 100025700(PDXP)
SHR: 100922295 100924589(PDXP) 116419009(PHOSPHO2)
PCW: 110205758(PDXP) 110211551(PHOSPHO2)
OAA: 100091800(PDXP)
GGA: 424160(PHOSPHO2) 771207(PDXP)
MGP: 100539695(PDXP) 100542382(PHOSPHO2)
CJO: 107313943(PDXP) 107316687(PHOSPHO2)
NMEL: 110393065(PDXP) 110400143(PHOSPHO2)
APLA: 101794607(PHOSPHO2) 101799043 113843327
ACYG: 106029977(PHOSPHO2) 106035787(PDXP)
TGU: 100219816(PHOSPHO2) 101234251(PDXP)
LSR: 110472775(PHOSPHO2) 110483791(PDXP)
SCAN: 103813599(PDXP) 103814419(PHOSPHO2)
GFR: 102033327(PDXP) 102044333(PHOSPHO2)
FAB: 101809714(PDXP) 101815279(PHOSPHO2)
PHI: 102108764(PDXP) 102113616(PHOSPHO2)
PMAJ: 107204187(PDXP) 107207480(PHOSPHO2)
CCAE: 111932106(PHOSPHO2) 111935173(PDXP)
CCW: 104693891(PHOSPHO2) 104696513(PDXP)
ETL: 114055402(PDXP) 114073767(PHOSPHO2)
FPG: 106112195(PDXP)
FCH: 106631635(PDXP) 114014216(PHOSPHO2)
CLV: 102095123(PHOSPHO2) 102098989(PDXP)
EGZ: 104128044(PHOSPHO2)
NNI: 104009988(PHOSPHO2)
ACUN: 113481988(PHOSPHO2) 113487950(PDXP)
PADL: 103918164(PHOSPHO2)
AAM: 106488247(PDXP) 106499198(PHOSPHO2)
ASN: 102376120(PDXP) 102382568(PHOSPHO2)
AMJ: 102566322(PDXP) 102570726(PHOSPHO2)
PSS: 102450474(PDXP) 102450695(PHOSPHO2)
CMY: 102933406(PHOSPHO2)
CPIC: 101950761(PHOSPHO2)
ACS: 100559885(phospho2) 100562224(pdxp)
PVT: 110075983(PDXP) 110076907(PHOSPHO2)
PBI: 103059635(PHOSPHO2)
PMUR: 107290303(PHOSPHO2)
TSR: 106544265(PHOSPHO2)
PMUA: 114607202(PHOSPHO2)
GJA: 107105933(PDXP) 107119693(PHOSPHO2)
XLA: 779316(phospho2.L)
XTR: 493318(phospho2)
NPR: 108785496(PHOSPHO2)
DRE: 561030(pdxp) 799638(phospho2)
IPU: 108271665(phospho2) 108277379(pdxp)
PHYP: 113544919(pdxp) 113545925(phospho2)
AMEX: 103024835(phospho2) 103032875(pdxp)
EEE: 113570300(phospho2) 113583766(pdxp)
LCO: 104919874(phospho2) 104920831(pdxp)
NCC: 104961275(phospho2) 104964351(pdxp)
MZE: 101464860(pdxp) 101485115
ONL: 100704477 100705958(pdxp)
OLA: 101158449(pdxp) 101174256
XMA: 102219566 102225249(pdxp)
PRET: 103462227 103470083(pdxp)
CVG: 107092655(pdxp) 107096031(phospho2)
NFU: 107381999(phospho2) 107394160(pdxp)
KMR: 108233719(pdxp) 108241596(phospho2)
ALIM: 106513663(pdxp) 106534911(phospho2)
AOCE: 111564709(pdxp) 111567203(phospho2)
CSEM: 103378978(phospho2) 103396959 103397631
POV: 109624747(phospho2) 109637080(pdxp)
LCF: 108882065(pdxp) 108897643(phospho2)
SDU: 111219985 111237762(pdxp)
SLAL: 111651685(pdxp) 111672261
HCQ: 109513960(phospho2) 109526995(pdxp)
BPEC: 110155147(phospho2) 110172127(pdxp)
MALB: 109956628 109969926(phospho2)
OTW: 112219704 112242041(phospho2) 112262792
SALP: 111957714 111961217 112078560(phospho2)
SFM: 108920705(phospho2) 108938493
PKI: 111839313(pdxp) 111841018(phospho2)
LCM: 102350970(PHOSPHO2) 102351909(PDXP)
CMK: 103176439(phospho2)
RTP: 109917160(phospho2)
CIN: 113475804
APLC: 110983821
SKO: 100374642
DME: Dmel_CG12237(CG12237) Dmel_CG14212(CG14212)
DSI: Dsimw501_GD17453(Dsim_GD17453) Dsimw501_GD24455(Dsim_GD24455)
DAN: 6503123
DVI: 6634543
MDE: 101891971
LCQ: 111688580
AAG: 5575050
AME: 725365
BIM: 100740933
BTER: 105666736
CCAL: 108631509
OBB: 114878402
SOC: 105192970
MPHA: 105836592
AEC: 105149951
ACEP: 105621298
PBAR: 105423117
VEM: 105562624
HST: 105186458
DQU: 106745743
CFO: 105248101
LHU: 105679863
PGC: 109853991
OBO: 105283699
PCF: 106787060
MDL: 103569628
TCA: 100141932
DPA: 109534241
ATD: 109605635
NVL: 108561852
BMOR: 101745817
BMAN: 114244171
PMAC: 106710189
PRAP: 110993710
HAW: 110380867
TNL: 113505595
DNX: 107163701
AGS: 114125555
RMD: 113550143
BTAB: 109034019
CLEC: 106670835
PVM: 113815557
CSCU: 111613261
PTEP: 107448827
PCAN: 112564507
CRG: 105338198
MYI: 110442689
OBI: 106883989
NVE: 5521298
EPA: 110254575
ADF: 107355999
AMIL: 114958750
PDAM: 113676502
SPIS: 111330826
DGT: 114524566
AQU: 105312510
ATH: AT1G17710(PEPC1) AT1G73010(PS2) AT4G29530
LJA: Lj0g3v0125959.1(Lj0g3v0125959.1) Lj0g3v0193989.1(Lj0g3v0193989.1) Lj0g3v0319789.1(Lj0g3v0319789.1) Lj3g3v0301740.1(Lj3g3v0301740.1) Lj3g3v0302750.1(Lj3g3v0302750.1) Lj3g3v2693540.1(Lj3g3v2693540.1) Lj3g3v2693540.2(Lj3g3v2693540.2)
SLY: 101246036 101259946(psi14C) 543790(psi14B) 544179(psi14A)
DOSA: Os01t0600500-01(Os01g0600500) Os02t0226200-01(Os02g0226200)
OBR: 102701047
ATS: 109739137(LOC109739137) 109747901(LOC109747901)
ZMA: 100281893(TIDP3606) 100502503 103636051
PPP: 112295379
CNE: CNI03770
CNB: CNBH3600
TASA: A1Q1_02576
ABP: AGABI1DRAFT112429(AGABI1DRAFT_112429)
ABV: AGABI2DRAFT192397(AGABI2DRAFT_192397)
MGL: MGL_1592
MRT: MRET_0683
SMIN: v1.2.000195.t1(symbB.v1.2.000195.t1)
SPAR: SPRG_03461
 » show all
Reference
1  [PMID:1322411]
  Authors
Fonda ML.
  Title
Purification and characterization of vitamin B6-phosphate phosphatase from human erythrocytes.
  Journal
J Biol Chem 267:15978-83 (1992)
Reference
2  [PMID:7625842]
  Authors
Fonda ML, Zhang YN.
  Title
Kinetic mechanism and divalent metal activation of human erythrocyte pyridoxal phosphatase.
  Journal
Arch Biochem Biophys 320:345-52 (1995)
DOI:10.1016/0003-9861(95)90018-7
Reference
3  [PMID:14522954]
  Authors
Jang YM, Kim DW, Kang TC, Won MH, Baek NI, Moon BJ, Choi SY, Kwon OS.
  Title
Human pyridoxal phosphatase. Molecular cloning, functional expression, and tissue distribution.
  Journal
J Biol Chem 278:50040-6 (2003)
DOI:10.1074/jbc.M309619200
  Sequence
[hsa:57026] [mmu:57028]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.74
IUBMB Enzyme Nomenclature: 3.1.3.74
ExPASy - ENZYME nomenclature database: 3.1.3.74
BRENDA, the Enzyme Database: 3.1.3.74
CAS: 9076-92-0

KEGG   REACTION: R00173
Entry
R00173                      Reaction                               

Name
pyridoxal-5'-phosphate phosphohydrolase
Definition
Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate
Equation
Reaction class
RC00017  C00018_C00250
Enzyme
Pathway
rn00750  Vitamin B6 metabolism
rn01100  Metabolic pathways
Orthology
K07758  pyridoxal phosphatase [EC:3.1.3.74]
K13248  pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74]
Other DBs
RHEA: 20536

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