KEGG ORTHOLOGY: K07828

ORTHOLOGY: K07828

Entry

K07828                      KO

Symbol

NRAS

Name

GTPase NRas

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map01522

Endocrine resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04062

Chemokine signaling pathway

map04068

FoxO signaling pathway

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04137

Mitophagy - animal

map04140

Autophagy - animal

map04150

mTOR signaling pathway

map04151

PI3K-Akt signaling pathway

map04210

Apoptosis

map04211

Longevity regulating pathway

map04213

Longevity regulating pathway - multiple species

map04218

Cellular senescence

map04360

Axon guidance

map04370

VEGF signaling pathway

map04371

Apelin signaling pathway

map04540

Gap junction

map04550

Signaling pathways regulating pluripotency of stem cells

map04625

C-type lectin receptor signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04660

T cell receptor signaling pathway

map04662

B cell receptor signaling pathway

map04664

Fc epsilon RI signaling pathway

map04714

Thermogenesis

map04720

Long-term potentiation

map04722

Neurotrophin signaling pathway

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04730

Long-term depression

map04810

Regulation of actin cytoskeleton

map04910

Insulin signaling pathway

map04912

GnRH signaling pathway

map04915

Estrogen signaling pathway

map04916

Melanogenesis

map04917

Prolactin signaling pathway

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04926

Relaxin signaling pathway

map04929

GnRH secretion

map04933

AGE-RAGE signaling pathway in diabetic complications

map04935

Growth hormone synthesis, secretion and action

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05034

Alcoholism

map05160

Hepatitis C

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05170

Human immunodeficiency virus 1 infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05208

Chemical carcinogenesis - reactive oxygen species

map05210

Colorectal cancer

map05211

Renal cell carcinoma

map05213

Endometrial cancer

map05214

Glioma

map05215

Prostate cancer

map05216

Thyroid cancer

map05218

Melanoma

map05219

Bladder cancer

map05220

Chronic myeloid leukemia

map05221

Acute myeloid leukemia

map05223

Non-small cell lung cancer

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05230

Central carbon metabolism in cancer

map05231

Choline metabolism in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05417

Lipid and atherosclerosis

Disease

H00003

Acute myeloid leukemia

H00010

Multiple myeloma

H00016

Oral cancer

H00018

Gastric cancer

H00032

Thyroid cancer

H00033

Adrenal carcinoma

H00038

Melanoma

H00108

Autoimmune lymphoproliferative syndromes

H00523

Noonan syndrome and related disorders

H01666

Angiosarcoma

H01738

Noonan syndrome

H02410

Myelodysplastic/myeloproliferative neoplasms

H02411

Chronic myelomonocytic leukemia

H02412

Atypical chronic myeloid leukemia

H02425

Erdheim-Chester disease

H02541

Juvenile myelomonocytic leukemia

H02627

Epidermal nevus

H02628

Schimmelpenning-Feuerstein-Mims syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K07828  NRAS; GTPase NRas
   04012 ErbB signaling pathway
    K07828  NRAS; GTPase NRas
   04014 Ras signaling pathway
    K07828  NRAS; GTPase NRas
   04015 Rap1 signaling pathway
    K07828  NRAS; GTPase NRas
   04370 VEGF signaling pathway
    K07828  NRAS; GTPase NRas
   04371 Apelin signaling pathway
    K07828  NRAS; GTPase NRas
   04068 FoxO signaling pathway
    K07828  NRAS; GTPase NRas
   04072 Phospholipase D signaling pathway
    K07828  NRAS; GTPase NRas
   04071 Sphingolipid signaling pathway
    K07828  NRAS; GTPase NRas
   04151 PI3K-Akt signaling pathway
    K07828  NRAS; GTPase NRas
   04150 mTOR signaling pathway
    K07828  NRAS; GTPase NRas
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K07828  NRAS; GTPase NRas
   04137 Mitophagy - animal
    K07828  NRAS; GTPase NRas
  09143 Cell growth and death
   04210 Apoptosis
    K07828  NRAS; GTPase NRas
   04218 Cellular senescence
    K07828  NRAS; GTPase NRas
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K07828  NRAS; GTPase NRas
   04550 Signaling pathways regulating pluripotency of stem cells
    K07828  NRAS; GTPase NRas
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K07828  NRAS; GTPase NRas
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K07828  NRAS; GTPase NRas
   04650 Natural killer cell mediated cytotoxicity
    K07828  NRAS; GTPase NRas
   04660 T cell receptor signaling pathway
    K07828  NRAS; GTPase NRas
   04662 B cell receptor signaling pathway
    K07828  NRAS; GTPase NRas
   04664 Fc epsilon RI signaling pathway
    K07828  NRAS; GTPase NRas
   04062 Chemokine signaling pathway
    K07828  NRAS; GTPase NRas
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07828  NRAS; GTPase NRas
   04929 GnRH secretion
    K07828  NRAS; GTPase NRas
   04912 GnRH signaling pathway
    K07828  NRAS; GTPase NRas
   04915 Estrogen signaling pathway
    K07828  NRAS; GTPase NRas
   04917 Prolactin signaling pathway
    K07828  NRAS; GTPase NRas
   04921 Oxytocin signaling pathway
    K07828  NRAS; GTPase NRas
   04926 Relaxin signaling pathway
    K07828  NRAS; GTPase NRas
   04935 Growth hormone synthesis, secretion and action
    K07828  NRAS; GTPase NRas
   04919 Thyroid hormone signaling pathway
    K07828  NRAS; GTPase NRas
   04916 Melanogenesis
    K07828  NRAS; GTPase NRas
  09156 Nervous system
   04725 Cholinergic synapse
    K07828  NRAS; GTPase NRas
   04726 Serotonergic synapse
    K07828  NRAS; GTPase NRas
   04720 Long-term potentiation
    K07828  NRAS; GTPase NRas
   04730 Long-term depression
    K07828  NRAS; GTPase NRas
   04722 Neurotrophin signaling pathway
    K07828  NRAS; GTPase NRas
  09158 Development and regeneration
   04360 Axon guidance
    K07828  NRAS; GTPase NRas
  09149 Aging
   04211 Longevity regulating pathway
    K07828  NRAS; GTPase NRas
   04213 Longevity regulating pathway - multiple species
    K07828  NRAS; GTPase NRas
  09159 Environmental adaptation
   04714 Thermogenesis
    K07828  NRAS; GTPase NRas
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07828  NRAS; GTPase NRas
   05206 MicroRNAs in cancer
    K07828  NRAS; GTPase NRas
   05205 Proteoglycans in cancer
    K07828  NRAS; GTPase NRas
   05207 Chemical carcinogenesis - receptor activation
    K07828  NRAS; GTPase NRas
   05208 Chemical carcinogenesis - reactive oxygen species
    K07828  NRAS; GTPase NRas
   05203 Viral carcinogenesis
    K07828  NRAS; GTPase NRas
   05230 Central carbon metabolism in cancer
    K07828  NRAS; GTPase NRas
   05231 Choline metabolism in cancer
    K07828  NRAS; GTPase NRas
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07828  NRAS; GTPase NRas
  09162 Cancer: specific types
   05210 Colorectal cancer
    K07828  NRAS; GTPase NRas
   05225 Hepatocellular carcinoma
    K07828  NRAS; GTPase NRas
   05226 Gastric cancer
    K07828  NRAS; GTPase NRas
   05214 Glioma
    K07828  NRAS; GTPase NRas
   05216 Thyroid cancer
    K07828  NRAS; GTPase NRas
   05221 Acute myeloid leukemia
    K07828  NRAS; GTPase NRas
   05220 Chronic myeloid leukemia
    K07828  NRAS; GTPase NRas
   05218 Melanoma
    K07828  NRAS; GTPase NRas
   05211 Renal cell carcinoma
    K07828  NRAS; GTPase NRas
   05219 Bladder cancer
    K07828  NRAS; GTPase NRas
   05215 Prostate cancer
    K07828  NRAS; GTPase NRas
   05213 Endometrial cancer
    K07828  NRAS; GTPase NRas
   05224 Breast cancer
    K07828  NRAS; GTPase NRas
   05223 Non-small cell lung cancer
    K07828  NRAS; GTPase NRas
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07828  NRAS; GTPase NRas
   05170 Human immunodeficiency virus 1 infection
    K07828  NRAS; GTPase NRas
   05161 Hepatitis B
    K07828  NRAS; GTPase NRas
   05160 Hepatitis C
    K07828  NRAS; GTPase NRas
   05163 Human cytomegalovirus infection
    K07828  NRAS; GTPase NRas
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07828  NRAS; GTPase NRas
   05165 Human papillomavirus infection
    K07828  NRAS; GTPase NRas
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07828  NRAS; GTPase NRas
   05022 Pathways of neurodegeneration - multiple diseases
    K07828  NRAS; GTPase NRas
  09165 Substance dependence
   05034 Alcoholism
    K07828  NRAS; GTPase NRas
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07828  NRAS; GTPase NRas
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K07828  NRAS; GTPase NRas
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K07828  NRAS; GTPase NRas
   01522 Endocrine resistance
    K07828  NRAS; GTPase NRas
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07828  NRAS; GTPase NRas
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07828  NRAS; GTPase NRas
   04031 GTP-binding proteins
    K07828  NRAS; GTPase NRas
Membrane trafficking [BR:ko04131]
Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    K07828  NRAS; GTPase NRas
Endocytosis
  Macropinocytosis
   Ras GTPases
    K07828  NRAS; GTPase NRas
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07828  NRAS; GTPase NRas
  Exosomal proteins of other body fluids (saliva and urine)
   K07828  NRAS; GTPase NRas
  Exosomal proteins of breast cancer cells
   K07828  NRAS; GTPase NRas
  Exosomal proteins of colorectal cancer cells
   K07828  NRAS; GTPase NRas
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    K07828  NRAS; GTPase NRas

Genes

HSA:	4893(NRAS)

PTR:	742713(NRAS)

PPS:	100970465(NRAS)

GGO:	101146562(NRAS)

PON:	100174317(NRAS)

PPYG:

129019833(NRAS)

NLE:	100592103(NRAS)

HMH:	116469568(NRAS)

SSYN:

134734188(NRAS)

MCC:	709089(NRAS)

MCF:	102137913(NRAS)

MTHB:

126930824

MNI:	105479146(NRAS)

CSAB:

103224167(NRAS)

CATY:

105596344(NRAS)

PANU:

101026253(NRAS)

TGE:	112619416(NRAS)

MLEU:

105554356(NRAS)

RRO:	104669078(NRAS)

RBB:	108528122(NRAS)

TFN:	117074634(NRAS)

PTEH:

111549619(NRAS)

CANG:

105504520 105505387(NRAS)

CJC:	100414782(NRAS) 108591807

SBQ:	101036877(NRAS)

CIMI:

108289201 108301162(NRAS)

ANAN:

105727008(NRAS) 105730743

CSYR:

103259236(NRAS)

MMUR:

105878710(NRAS)

LCAT:

123635081(NRAS)

PCOQ:

105810591(NRAS)

OGA:	100949583(NRAS)

MMU:	18176(Nras)

MCAL:

110290873(Nras)

MPAH:

110320340(Nras)

RNO:	24605(Nras)

MCOC:

116093530(Nras)

ANU:	117706966(Nras)

MUN:	110544642 110544765(Nras)

CGE:	100757614(Nras)

MAUA:

101841999(Nras) 121137054

PROB:

127233129(Nras)

PLEU:

114698582(Nras)

MORG:

121437938(Nras)

MFOT:

126510868

AAMP:

119801497(Nras)

NGI:	103734938(Nras)

HGL:	101719269(Nras)

CPOC:

100135584(Nras)

CCAN:

109696062(Nras)

DORD:

105991947(Nras)

DSP:	122118367(Nras)

PLOP:

125355453(Nras)

NCAR:

124962389

MMMA:

107156178(Nras)

OCU:

100344241

OPI:	101524465(NRAS)

TUP:	102496534(NRAS)

GVR:	103589329(NRAS)

CFA:	403872(NRAS)

CLUD:

112664166(NRAS)

VVP:	112916766(NRAS)

VLG:	121491321(NRAS)

NPO:	129501466(NRAS)

AML:	100464196(NRAS)

UMR:	103669422(NRAS)

UAH:	113244394(NRAS)

UAR:	123795037(NRAS)

ELK:

111143238

LLV:

125098043

MPUF:

101683038(NRAS)

MNP:	132001334(NRAS) 132002077

MLK:	131810307(NRAS) 131810524

NVS:	122899136 122900359(NRAS)

ORO:	101363525(NRAS)

EJU:	114207931(NRAS)

ZCA:	113931879(NRAS)

MLX:	118000495(NRAS)

NSU:	110580342(NRAS)

LWW:	102746431(NRAS)

FCA:	751105(NRAS)

PYU:	121027738(NRAS)

PCOO:

112848478(NRAS)

PBG:	122480981(NRAS)

PVIV:

125171937(NRAS)

LRUF:

124516245

PTG:	102952980(NRAS)

PPAD:

109272105(NRAS)

PUC:

125912218

AJU:

106969596

HHV:	120243068(NRAS)

BTA:	506322(NRAS)

BOM:	102269203(NRAS)

BIU:	109555890(NRAS)

BBUB:

102399487(NRAS)

BBIS:

104981582(NRAS)

CHX:	102187180(NRAS)

OAS:	101102438(NRAS)

BTAX:

128044537(NRAS)

ODA:	120856043(NRAS)

CCAD:

122435924(NRAS)

MBEZ:

129541808(NRAS)

SSC:	100739349(NRAS)

CFR:	102509562(NRAS)

CBAI:

105079555(NRAS)

CDK:	105089630(NRAS)

VPC:	102534785(NRAS)

BACU:

103004931(NRAS)

BMUS:

118893681(NRAS)

LVE:	103068734(NRAS)

OOR:	101276138(NRAS)

DLE:	111179996(NRAS)

PCAD:

102982641(NRAS) 102992439

PSIU:

116739088(NRAS)

NASI:

112413065(NRAS)

ECB:	100059469(NRAS)

EPZ:	103552675(NRAS)

EAI:	106835678(NRAS)

MYB:	102247606(NRAS)

MYD:	102761492(NRAS)

MMYO:

118672986(NRAS)

MLF:	102430744(NRAS)

MDT:	132221210(NRAS)

PKL:	118727253(NRAS)

EFUS:

103291212(NRAS)

MNA:	107545303(NRAS)

DRO:	112313707(NRAS)

SHON:

118981977(NRAS)

AJM:	119041711(NRAS)

PDIC:

114489186(NRAS)

PHAS:

123804414(NRAS)

MMF:	118637822(NRAS)

PPAM:

129063946(NRAS)

HAI:	109377015(NRAS)

RFQ:	117014672(NRAS)

PALE:

102885950(NRAS)

PGIG:

120585069(NRAS)

PVP:	105296550(NRAS)

RAY:	107499847(NRAS)

MJV:	108398047(NRAS)

TOD:	119236713(NRAS)

SARA:

101559343(NRAS)

SETR:

125997372(NRAS)

LAV:	100659051(NRAS)

TMU:

101344230

ETF:	101649328 101653520(NRAS)

DNM:	101414240 101430817(NRAS)

MDO:	100022523 554197(NRAS)

GAS:	123232515 123247194(NRAS)

SHR:	100928986(NRAS)

AFZ:	127538788 127538790 127538791 127538792 127538794 127541494 127559280

PCW:	110202309 110203410 110203411 110219182(NRAS)

TVP:	118856865(NRAS)

OAA:	100074671(NRAS)

GGA:	419885(NRAS)

PCOC:

116237002(NRAS)

MGP:	104914532(NRAS)

CJO:	107324818(NRAS)

TPAI:

128088218(NRAS)

LMUT:

125684092(NRAS)

NMEL:

110388133(NRAS)

APLA:

101804733(NRAS)

ACYG:

106041320(NRAS)

CATA:

118255298(NRAS)

AFUL:

116498924(NRAS)

TGU:	100222058(NRAS)

LSR:	110473049(NRAS)

SCAN:

103822405(NRAS)

PMOA:

120497648(NRAS)

OTC:	121345673(NRAS)

PRUF:

121349762(NRAS)

GFR:	102039955(NRAS)

FAB:	101813585(NRAS)

OMA:	130263584(NRAS)

PHI:	102110285(NRAS)

PMAJ:

107214761(NRAS)

CCAE:

111939625(NRAS)

CCW:	104692410(NRAS)

CBRC:

103625276(NRAS)

ETL:	114064402(NRAS)

ZAB:	102063862(NRAS)

ZLE:	135458244(NRAS)

ACHL:

103811226

SVG:	106851063(NRAS)

MMEA:

130578859(NRAS)

HRT:	120762833(NRAS)

SATI:

136371498(NRAS)

FPG:	101921486(NRAS)

FCH:	102054942(NRAS)

CCRI:

104156287(NRAS)

NNT:	104401663(NRAS)

SHAB:

115602282(NRAS)

ACUN:

113488912(NRAS)

TALA:

104364594(NRAS)

ACHC:

115335439(NRAS)

HALD:

104318405

HLE:	104838685(NRAS)

AGEN:

126051882

GCL:

127026157

CSTI:

104551897

LDI:	104346001(NRAS)

MNB:	103781606(NRAS)

DPUB:

104296307(NRAS)

AVIT:

104276512(NRAS)

BRHI:

104499025

EGZ:	104126779(NRAS)

NNI:	104010364(NRAS)

PCRI:

104025881

PCAO:

104050760

PADL:

103923578(NRAS)

AFOR:

103893660(NRAS)

FGA:	104071347(NRAS)

GSTE:

104260191

CLV:	102098728(NRAS)

MUI:	104535039(NRAS)

PGUU:

104462148(NRAS)

PLET:

104617220(NRAS)

EHS:

104504914

CMAC:

104480086

CUCA:

104067100(NRAS)

TEO:

104381249

BREG:

104635027

OHA:	104333531(NRAS)

ACAR:

104531552

CPEA:

104392909(NRAS)

CVF:	104289524(NRAS)

RTD:	128900210(NRAS)

AAM:	106485268(NRAS)

AROW:

112971673(NRAS)

NPD:	112951487(NRAS)

TGT:	104573975(NRAS)

DNE:	112990244(NRAS)

SCAM:

104142365(NRAS)

ASN:	102382019(NRAS)

AMJ:	102566357(NRAS)

CPOO:

109317850(NRAS)

GGN:	109295326(NRAS)

PSS:	102447991(NRAS)

CCAY:

125625144(NRAS)

DCC:	119846218(NRAS)

CPIC:

101949923(NRAS)

TST:	117875723(NRAS)

CABI:

116816930(NRAS)

MRV:	120404663(NRAS)

ACS:	100565176(nras)

ASAO:

132773340(NRAS)

PVT:	110072322(NRAS)

SUND:

121929449(NRAS)

PBI:	103066291(NRAS)

PMUR:

107284053(NRAS)

CTIG:

120314134(NRAS)

TSR:

106556469

PGUT:

117663788(NRAS)

APRI:

131195174(NRAS)

PTEX:

113444286(NRAS)

NSS:	113416978(NRAS)

VKO:	123032138(NRAS)

PMUA:

114599398(NRAS)

PRAF:

128416210(NRAS)

ZVI:	118089245(NRAS)

HCG:	128324461(NRAS)

STOW:

125433511(NRAS)

EMC:	129330049(NRAS)

XLA:	399446(nras.L)

XTR:	549517(nras)

NPR:	108799544(NRAS)

RTEM:

120927024(NRAS)

BBUF:

120994996(NRAS)

BGAR:

122933471(NRAS)

MUO:	115481569(NRAS)

GSH:	117347342(NRAS)

DRE:	30380(nras)

SRX:	107725308 107734518

SANH:

107664995 107674363

SGH:	107566814 107598969

CCAR:

109084682 109084683

CAUA:

113071752 113083541 113106980

CGIB:

127963616 128018924

PTET:

122350810(nras)

LROH:

127169998(nras)

OMC:	131545807(nras)

PPRM:

120474677(nras)

RKG:	130091702(nras)

MAMB:

125279259(nras)

CIDE:

127517208

CERY:

137026886(nras)

MASI:

127415059 127423940

TROS:

130567677(nras)

TDW:	130439916(nras)

MANU:

129413697(nras)

IPU:

100305071

IFU:	128608137(nras)

PHYP:

113535014(nras)

SMEO:

124399950(nras)

TFD:	113641175(zgc:55558) 113645799(nras)

TVC:	132853276(nras)

TRN:	134318282(nras)

AMEX:

103039914(nras)

CMAO:

118813822(nras)

EEE:	113577375(nras)

CHAR:

105889759(nras)

SFM:	108928283(nras)

PKI:	111853914(nras)

AANG:

118208260(nras)

LOC:	102691327(nras)

PSPA:

121300074 121300091

ARUT:

117428047 117962404

PSEX:

120526283(nras)

LCM:	102361045(NRAS)

CMK:	103189723(nras)

RTP:	109917328(nras)

CPLA:

122563298(nras)

HOC:	132828445(nras)

LERI:

129708834(nras)

BFO:

118430016

EIV:	EIN_454370

» show all

Reference

PMID:6616621

Authors

Taparowsky E, Shimizu K, Goldfarb M, Wigler M

Title

Structure and activation of the human N-ras gene.

Journal

Cell 34:581-6 (1983)
DOI:10.1016/0092-8674(83)90390-2

Sequence

[hsa:4893]

Reference

PMID:22983396

Authors

Kwong LN, Costello JC, Liu H, Jiang S, Helms TL, Langsdorf AE, Jakubosky D, Genovese G, Muller FL, Jeong JH, Bender RP, Chu GC, Flaherty KT, Wargo JA, Collins JJ, Chin L

Title

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.

Journal

Nat Med 18:1503-10 (2012)
DOI:10.1038/nm.2941

Reference

PMID:24586049

Authors

Eisfeld AK, Schwind S, Hoag KW, Walker CJ, Liyanarachchi S, Patel R, Huang X, Markowitz J, Duan W, Otterson GA, Carson WE 3rd, Marcucci G, Bloomfield CD, de la Chapelle A

Title

NRAS isoforms differentially affect downstream pathways, cell growth, and cell transformation.

Journal

Proc Natl Acad Sci U S A 111:4179-84 (2014)
DOI:10.1073/pnas.1401727111

Sequence

[hsa:4893]

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (160)   
   KEGG PATHWAY (160)   
Disease (18)   
   KEGG DISEASE (18)   
Gene (443)   
   KEGG GENES (350)   
   KEGG MGENES (15)   
   RefGene (75)   
   OC (3)   
Literature (3)   
   PubMed (3)   
All databases (628)   

Download RDF

ORTHOLOGY: K07827

Entry

K07827                      KO

Symbol

KRAS, KRAS2

Name

GTPase KRas

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map01522

Endocrine resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04013

MAPK signaling pathway - fly

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04062

Chemokine signaling pathway

map04068

FoxO signaling pathway

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04113

Meiosis - yeast

map04137

Mitophagy - animal

map04138

Autophagy - yeast

map04140

Autophagy - animal

map04150

mTOR signaling pathway

map04151

PI3K-Akt signaling pathway

map04210

Apoptosis

map04211

Longevity regulating pathway

map04213

Longevity regulating pathway - multiple species

map04214

Apoptosis - fly

map04218

Cellular senescence

map04320

Dorso-ventral axis formation

map04360

Axon guidance

map04370

VEGF signaling pathway

map04371

Apelin signaling pathway

map04540

Gap junction

map04550

Signaling pathways regulating pluripotency of stem cells

map04625

C-type lectin receptor signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04660

T cell receptor signaling pathway

map04662

B cell receptor signaling pathway

map04664

Fc epsilon RI signaling pathway

map04714

Thermogenesis

map04720

Long-term potentiation

map04722

Neurotrophin signaling pathway

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04730

Long-term depression

map04810

Regulation of actin cytoskeleton

map04910

Insulin signaling pathway

map04912

GnRH signaling pathway

map04914

Progesterone-mediated oocyte maturation

map04915

Estrogen signaling pathway

map04916

Melanogenesis

map04917

Prolactin signaling pathway

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04926

Relaxin signaling pathway

map04929

GnRH secretion

map04933

AGE-RAGE signaling pathway in diabetic complications

map04935

Growth hormone synthesis, secretion and action

map04960

Aldosterone-regulated sodium reabsorption

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05034

Alcoholism

map05160

Hepatitis C

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05170

Human immunodeficiency virus 1 infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05208

Chemical carcinogenesis - reactive oxygen species

map05210

Colorectal cancer

map05211

Renal cell carcinoma

map05212

Pancreatic cancer

map05213

Endometrial cancer

map05214

Glioma

map05215

Prostate cancer

map05216

Thyroid cancer

map05218

Melanoma

map05219

Bladder cancer

map05220

Chronic myeloid leukemia

map05221

Acute myeloid leukemia

map05223

Non-small cell lung cancer

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05230

Central carbon metabolism in cancer

map05231

Choline metabolism in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05417

Lipid and atherosclerosis

Disease

H00003

Acute myeloid leukemia

H00010

Multiple myeloma

H00014

Non-small cell lung cancer

H00016

Oral cancer

H00018

Gastric cancer

H00019

Pancreatic cancer

H00020

Colorectal cancer

H00026

Endometrial cancer

H00027

Ovarian cancer

H00030

Cervical cancer

H00032

Thyroid cancer

H00040

Squamous cell carcinoma

H00041

Kaposi sarcoma

H00046

Cholangiocarcinoma

H00047

Gallbladder cancer

H00458

Syndromic craniosynostoses

H00523

Noonan syndrome and related disorders

H01557

Hepatic angiosarcoma

H01592

Medullary thyroid cancer

H01666

Angiosarcoma

H01738

Noonan syndrome

H01745

Cardiofaciocutaneous syndrome

H02410

Myelodysplastic/myeloproliferative neoplasms

H02411

Chronic myelomonocytic leukemia

H02412

Atypical chronic myeloid leukemia

H02425

Erdheim-Chester disease

H02541

Juvenile myelomonocytic leukemia

H02628

Schimmelpenning-Feuerstein-Mims syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04013 MAPK signaling pathway - fly
    K07827  KRAS, KRAS2; GTPase KRas
   04012 ErbB signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04014 Ras signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04015 Rap1 signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04370 VEGF signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04371 Apelin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04068 FoxO signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04072 Phospholipase D signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04071 Sphingolipid signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04151 PI3K-Akt signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04150 mTOR signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K07827  KRAS, KRAS2; GTPase KRas
   04138 Autophagy - yeast
    K07827  KRAS, KRAS2; GTPase KRas
   04137 Mitophagy - animal
    K07827  KRAS, KRAS2; GTPase KRas
  09143 Cell growth and death
   04113 Meiosis - yeast
    K07827  KRAS, KRAS2; GTPase KRas
   04210 Apoptosis
    K07827  KRAS, KRAS2; GTPase KRas
   04214 Apoptosis - fly
    K07827  KRAS, KRAS2; GTPase KRas
   04218 Cellular senescence
    K07827  KRAS, KRAS2; GTPase KRas
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K07827  KRAS, KRAS2; GTPase KRas
   04550 Signaling pathways regulating pluripotency of stem cells
    K07827  KRAS, KRAS2; GTPase KRas
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K07827  KRAS, KRAS2; GTPase KRas
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04650 Natural killer cell mediated cytotoxicity
    K07827  KRAS, KRAS2; GTPase KRas
   04660 T cell receptor signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04662 B cell receptor signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04664 Fc epsilon RI signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04062 Chemokine signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
  09152 Endocrine system
   04910 Insulin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04929 GnRH secretion
    K07827  KRAS, KRAS2; GTPase KRas
   04912 GnRH signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04915 Estrogen signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04914 Progesterone-mediated oocyte maturation
    K07827  KRAS, KRAS2; GTPase KRas
   04917 Prolactin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04921 Oxytocin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04926 Relaxin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04935 Growth hormone synthesis, secretion and action
    K07827  KRAS, KRAS2; GTPase KRas
   04919 Thyroid hormone signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04916 Melanogenesis
    K07827  KRAS, KRAS2; GTPase KRas
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K07827  KRAS, KRAS2; GTPase KRas
  09156 Nervous system
   04725 Cholinergic synapse
    K07827  KRAS, KRAS2; GTPase KRas
   04726 Serotonergic synapse
    K07827  KRAS, KRAS2; GTPase KRas
   04720 Long-term potentiation
    K07827  KRAS, KRAS2; GTPase KRas
   04730 Long-term depression
    K07827  KRAS, KRAS2; GTPase KRas
   04722 Neurotrophin signaling pathway
    K07827  KRAS, KRAS2; GTPase KRas
  09158 Development and regeneration
   04320 Dorso-ventral axis formation
    K07827  KRAS, KRAS2; GTPase KRas
   04360 Axon guidance
    K07827  KRAS, KRAS2; GTPase KRas
  09149 Aging
   04211 Longevity regulating pathway
    K07827  KRAS, KRAS2; GTPase KRas
   04213 Longevity regulating pathway - multiple species
    K07827  KRAS, KRAS2; GTPase KRas
  09159 Environmental adaptation
   04714 Thermogenesis
    K07827  KRAS, KRAS2; GTPase KRas
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05206 MicroRNAs in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05205 Proteoglycans in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05207 Chemical carcinogenesis - receptor activation
    K07827  KRAS, KRAS2; GTPase KRas
   05208 Chemical carcinogenesis - reactive oxygen species
    K07827  KRAS, KRAS2; GTPase KRas
   05203 Viral carcinogenesis
    K07827  KRAS, KRAS2; GTPase KRas
   05230 Central carbon metabolism in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05231 Choline metabolism in cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K07827  KRAS, KRAS2; GTPase KRas
  09162 Cancer: specific types
   05210 Colorectal cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05212 Pancreatic cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05225 Hepatocellular carcinoma
    K07827  KRAS, KRAS2; GTPase KRas
   05226 Gastric cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05214 Glioma
    K07827  KRAS, KRAS2; GTPase KRas
   05216 Thyroid cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05221 Acute myeloid leukemia
    K07827  KRAS, KRAS2; GTPase KRas
   05220 Chronic myeloid leukemia
    K07827  KRAS, KRAS2; GTPase KRas
   05218 Melanoma
    K07827  KRAS, KRAS2; GTPase KRas
   05211 Renal cell carcinoma
    K07827  KRAS, KRAS2; GTPase KRas
   05219 Bladder cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05215 Prostate cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05213 Endometrial cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05224 Breast cancer
    K07827  KRAS, KRAS2; GTPase KRas
   05223 Non-small cell lung cancer
    K07827  KRAS, KRAS2; GTPase KRas
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07827  KRAS, KRAS2; GTPase KRas
   05170 Human immunodeficiency virus 1 infection
    K07827  KRAS, KRAS2; GTPase KRas
   05161 Hepatitis B
    K07827  KRAS, KRAS2; GTPase KRas
   05160 Hepatitis C
    K07827  KRAS, KRAS2; GTPase KRas
   05163 Human cytomegalovirus infection
    K07827  KRAS, KRAS2; GTPase KRas
   05167 Kaposi sarcoma-associated herpesvirus infection
    K07827  KRAS, KRAS2; GTPase KRas
   05165 Human papillomavirus infection
    K07827  KRAS, KRAS2; GTPase KRas
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07827  KRAS, KRAS2; GTPase KRas
   05022 Pathways of neurodegeneration - multiple diseases
    K07827  KRAS, KRAS2; GTPase KRas
  09165 Substance dependence
   05034 Alcoholism
    K07827  KRAS, KRAS2; GTPase KRas
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K07827  KRAS, KRAS2; GTPase KRas
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K07827  KRAS, KRAS2; GTPase KRas
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K07827  KRAS, KRAS2; GTPase KRas
   01522 Endocrine resistance
    K07827  KRAS, KRAS2; GTPase KRas
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07827  KRAS, KRAS2; GTPase KRas
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07827  KRAS, KRAS2; GTPase KRas
Membrane trafficking [BR:ko04131]
Endocytosis
  Macropinocytosis
   Ras GTPases
    K07827  KRAS, KRAS2; GTPase KRas
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    K07827  KRAS, KRAS2; GTPase KRas

Other DBs

COG:

COG1100

Genes

HSA:	3845(KRAS)

PTR:	473387(KRAS)

PPS:	100990801(KRAS)

GGO:	101144039(KRAS)

PON:	100462513(KRAS)

PPYG:

129009714(KRAS)

NLE:	100593773(KRAS)

HMH:	116472788(KRAS)

SSYN:

129483245(KRAS)

MCC:	707977(KRAS)

MCF:	102131483(KRAS)

MTHB:

126931572

MNI:	105492133(KRAS)

CSAB:

103218763(KRAS)

CATY:

105585038(KRAS)

PANU:

101017528(KRAS)

TGE:	112634105(KRAS)

MLEU:

105550009(KRAS)

RRO:	104670041(KRAS)

RBB:	108523748(KRAS)

PTEH:

111540622(KRAS)

CANG:

105515217(KRAS)

CJC:	118144179(KRAS)

SBQ:	101047035(KRAS)

CIMI:

108300272(KRAS)

ANAN:

105720562(KRAS)

CSYR:

103263630(KRAS)

MMUR:

105857286(KRAS)

LCAT:

123639921(KRAS)

PCOQ:

105807545(KRAS)

OGA:	100953050(KRAS)

MMU:	16653(Kras)

MCAL:

110296194(Kras)

MPAH:

110316221(Kras)

RNO:	24525(Kras)

MCOC:

116099791(Kras)

ANU:	117714902(Kras)

MUN:	110558913(Kras)

MAUA:

101835944(Kras)

PROB:

127213087(Kras)

PLEU:

114708477(Kras)

MORG:

121466497(Kras)

MFOT:

126515221

AAMP:

119804230 119806318(Kras)

NGI:	103736717(Kras)

HGL:	101718997(Kras)

CPOC:

100716262(Kras)

CCAN:

109687060(Kras)

DORD:

105992272(Kras)

DSP:	122098841(Kras)

PLOP:

125342925(Kras)

NCAR:

124982118 124991017

MMMA:

107152729(Kras)

OCU:	100347487 127489236

OPI:	101534080(KRAS)

TUP:	102500069(KRAS)

GVR:	103599501(KRAS)

CFA:	403871(KRAS)

CLUD:

112665533(KRAS)

VVP:	112917213(KRAS)

VLG:	121479900(KRAS)

NPO:	129505561(KRAS)

AML:	100483919(KRAS)

UMR:	103665244(KRAS)

UAH:	113257792(KRAS)

UAR:	123801699(KRAS)

ELK:

111159984

LLV:

125106241

MPUF:

101681333(KRAS)

MNP:	132019561(KRAS)

MLK:	131838926(KRAS)

NVS:	122892446(KRAS)

ORO:	101370458(KRAS)

EJU:	114216565(KRAS)

ZCA:	113921792(KRAS)

MLX:	118025572(KRAS)

NSU:	110580861(KRAS)

LWW:	102727145(KRAS)

FCA:	751104(KRAS)

PYU:	121038809(KRAS)

PCOO:

112868012(KRAS)

PBG:	122473961(KRAS)

PVIV:

125170295(KRAS)

LRUF:

124502703

PTG:	102957350(KRAS)

PPAD:

109268745(KRAS)

PUC:

125918906

AJU:

106968778

HHV:	120223531(KRAS)

BTA:	541140(KRAS)

BOM:	102286500(KRAS)

BIU:	109559581(KRAS)

BBUB:

102392995(KRAS)

BBIS:

105000225(KRAS)

CHX:	102172519(KRAS)

OAS:	101114005(KRAS)

BTAX:

128047937(KRAS)

ODA:	120858492(KRAS)

CCAD:

122423876(KRAS) 122446047

MBEZ:

129537164(KRAS)

SSC:	100518251(KRAS)

CFR:	102516372(KRAS)

CBAI:

105062297(KRAS)

CDK:	105100066(KRAS)

VPC:	102529990(KRAS)

BACU:

103015457(KRAS)

BMUS:

118901791(KRAS)

LVE:	103077579(KRAS)

OOR:	101281897(KRAS)

DLE:	111176851(KRAS)

PCAD:

102977125(KRAS)

PSIU:

116760326(KRAS)

NASI:

112391643(KRAS)

ECB:	100051785 100064473(KRAS)

EPZ:	103546629(KRAS)

EAI:	106825548(KRAS) 106829397

MYB:	102244940(KRAS)

MYD:	102762284(KRAS)

MMYO:

118649554(KRAS)

MLF:	102431999(KRAS)

MDT:	132227384(KRAS)

PKL:	118730853(KRAS)

EFUS:

103285154(KRAS)

MNA:	107525258(KRAS)

DRO:	112304041 112318275(KRAS)

SHON:

118978497(KRAS)

AJM:	119048987(KRAS)

PDIC:

114512682(KRAS)

PHAS:

123812406(KRAS)

MMF:	118624619(KRAS)

PPAM:

129084969(KRAS)

HAI:	109389264(KRAS)

RFQ:	117028978(KRAS)

PALE:

102895590(KRAS)

PGIG:

120618351(KRAS)

PVP:	105294059(KRAS)

RAY:	107497434(KRAS)

MJV:	108395842(KRAS)

TOD:	119247626(KRAS)

SARA:

101557531(KRAS)

SETR:

126022823(KRAS)

LAV:	100661512(KRAS)

TMU:

101347525

ETF:	101639926(KRAS)

DNM:	101412233(KRAS)

MDO:	554186(KRAS)

GAS:	123248684(KRAS) 123251828

SHR:	100915526(KRAS) 100927252 100929426

AFZ:	127537819 127537860 127538037 127538119 127538128 127538787 127538953 127539191 127539349 127539435 127539441 127541495 127564364 127564665 127564806 127564858 127564890 127564892

PCW:	110193352(KRAS)

TVP:	118830561 118833189 118833192 118833193 118833273 118833361 118850034(KRAS) 118857702

OAA:	100085430(KRAS)

GGA:	418207(KRAS)

PCOC:

116231417(KRAS)

MGP:	100151750(KRAS)

CJO:	107317023(KRAS)

TPAI:

128084496(KRAS)

LMUT:

125688361(KRAS)

NMEL:

110396332(KRAS)

APLA:

101793538(KRAS)

ACYG:

106038277(KRAS)

CATA:

118245139(KRAS)

AFUL:

116486326(KRAS)

TGU:	100227892(KRAS)

LSR:	110474885(KRAS)

SCAN:

103819595(KRAS)

OTC:	121332765(KRAS)

PRUF:

121354764(KRAS)

GFR:	102035876(KRAS)

FAB:	101809651(KRAS)

OMA:	130248575(KRAS)

PHI:	102112893(KRAS)

PMAJ:

107204562(KRAS)

CCAE:

111945773(KRAS)

CCW:	104696163(KRAS)

CBRC:

103623350(KRAS)

ETL:	114068618(KRAS)

ZAB:	102062345(KRAS)

ZLE:	135441525(KRAS)

ACHL:

103804109(KRAS)

SVG:	106860955(KRAS)

MMEA:

130576123(KRAS)

HRT:	120751789(KRAS)

SATI:

136361624(KRAS)

FPG:	101917762(KRAS)

FCH:	102052019(KRAS)

CCRI:

104156747(KRAS)

NNT:	104409733(KRAS)

ACUN:

113491163(KRAS)

TALA:

104360689(KRAS)

ACHC:

115352540(KRAS)

HALD:

104323482(KRAS)

HLE:	104836701(KRAS)

AGEN:

126047787

GCL:

127028489

CSTI:

104563088(KRAS)

LDI:	104346358(KRAS)

MNB:	103782490(KRAS)

DPUB:

104305177(KRAS)

AVIT:

104273514(KRAS)

BRHI:

104497670(KRAS)

EGZ:	104135137(KRAS)

NNI:	104012697(KRAS)

PCRI:

104038803(KRAS)

PCAO:

104040291

PADL:

103924322(KRAS)

AFOR:

103898696(KRAS)

FGA:

104071114

GSTE:

104250297

CLV:	102096076(KRAS)

MUI:	104537075(KRAS)

PGUU:

104463508(KRAS)

PLET:

104615251

EHS:

104504813

CMAC:

104475393(KRAS)

CUCA:

104067113(KRAS)

TEO:	104373851(KRAS)

BREG:

104634279(KRAS)

OHA:	104335264(KRAS)

ACAR:

104523735

CPEA:

104386764(KRAS)

CVF:	104281647(KRAS)

RTD:	128914000(KRAS)

AAM:	106488640(KRAS)

AROW:

112964650 112966580(KRAS)

NPD:	112950669(KRAS)

TGT:	104570791(KRAS)

DNE:	112978891(KRAS)

SCAM:

104154112(KRAS)

ASN:	102373235(KRAS) 112547860

AMJ:	102574430(KRAS) 102575936

CPOO:

109316381(KRAS) 109320833

GGN:	109296308(KRAS)

PSS:	102447251 102450646(KRAS)

CMY:	102941364(KRAS) 102943017

CCAY:

125624971(KRAS) 125628281

DCC:	119847080 119854719(KRAS)

CPIC:

101940651(KRAS) 101951310

TST:	117883516(KRAS)

CABI:

116830341(KRAS) 116840087

MRV:	120388368 120407327(KRAS)

ACS:	100559807 100563575(kras)

ASAO:

132775705(KRAS) 132777938

PVT:	110078528 110082993(KRAS)

SUND:

121931822(KRAS) 121935008

PBI:	103056809 103057417(KRAS)

PMUR:

107282493 107295639(KRAS) 107296269

CTIG:

120304533 120309804(KRAS)

TSR:	106538715 106556456

PGUT:

117669116 117679853(KRAS)

APRI:

131198388 131202281(KRAS)

PTEX:

113441228(KRAS) 113443525

NSS:	113418546 113419054(KRAS)

VKO:	123022284(KRAS) 123032158

PMUA:

114605215(KRAS) 114608097

PRAF:

128399368 128422664(KRAS)

ZVI:	118090655(KRAS) 118094849

HCG:	128325732(KRAS) 128330371

GJA:	107106941(KRAS) 107116614

STOW:

125434327(KRAS) 125444900

EMC:	129336091(KRAS) 129338629

XLA:	100505423 108697792(kras.S) 108712520(krasl.S) 397771(kras.L)

XTR:	100485959(krasl) 493396(kras)

NPR:	108797553(KRAS) 108803002

RTEM:

120916588 120932753(KRAS)

BBUF:

121001799 121004973(KRAS)

BGAR:

122928462(KRAS) 122928630

MUO:	115466597 115477562(KRAS)

GSH:	117363548(KRAS) 117367850

DRE:	393228(zgc:55558) 445289(kras)

SRX:	107731060 107742054 107754174 107758760

SANH:

107653435 107675271 107675456

SGH:	107549277 107560753 107567516 107595236

CCAR:

109050773 109059246 109069553

CAUA:

113043474 113043560 113046915 113067076

CGIB:

127947063 127948124 127952884 128014233

PTET:

122330578(kras) 122330765 122341555

LROH:

127156990(kras) 127160738(zgc:55558)

OMC:	131534236(kras) 131536821(zgc:55558)

PPRM:

120458984(kras) 120489627

RKG:	130075255(zgc:55558) 130086042(kras)

MAMB:

125246538(kras) 125279450(zgc:55558)

CIDE:

127506985 127508487(zgc:55558)

CERY:

137015480(kras) 137017475(zgc:55558)

MASI:

127436201 127437280 127450507 127451777

TROS:

130551760(kras) 130561674(zgc:55558)

TDW:	130414055(kras) 130425672(zgc:55558)

MANU:

129433080(kras) 129436261(zgc:55558)

IPU:	108258948(zgc:55558) 108274959(kras)

IFU:	128601824(zgc:55558) 128618149(kras)

PHYP:

113528179 113529743

SMEO:

124392449(kras) 124396747(zgc:55558)

TFD:	113660103(kras)

TVC:	132856574(kras) 132860818(zgc:55558)

TRN:	134309791(kras) 134335869(zgc:55558)

AMEX:

103023536(zgc:55558) 103038241(kras)

CMAO:

118811569(kras) 118821270(zgc:55558)

EEE:	113588524 113589852

CHAR:

105894964 105897575 105900436(kras)

TRU:	101069736 101077708(kras)

TFS:	130514432(zgc:55558) 130536798(kras)

TNG:	GSTEN00022812G001

LCO:	104924376(kras) 104930345

NCC:	104950842 104968078(kras)

TBEN:

117491315(kras) 117492706(zgc:55558)

CGOB:

115009461(kras) 115012331

PGEO:

117448736(kras) 117450798(zgc:55558)

GACU:

117544128(zgc:55558) 117545716(kras)

EMAC:

134859177(kras) 134877937(zgc:55558)

ELY:	117262168(kras) 117268371(zgc:55558)

EFO:	125880010(zgc:55558) 125887085(kras)

PLEP:

121949688(kras) 121956927

SLUC:

116062325(kras) 116065199(zgc:55558)

ECRA:

117948705(kras) 117958506(zgc:55558)

ESP:	116694484(kras) 116703772

PFLV:

114559939(kras) 114569569

GAT:	120808991 120812377(kras) 120827241

PPUG:

119195920(kras) 119220140

AFB:	129097851(zgc:55558) 129107733(kras)

CLUM:

117731941(kras) 117735017(zgc:55558)

PSWI:

130189051(zgc:55558) 130195239(kras)

MSAM:

119886647 119893343(kras)

SCHU:

122874834(kras)

CUD:	121514916(kras) 121529454

ALAT:

119014285 119023707(kras)

MZE:	101465888(kras) 101485266

ONL:	100694749(kras) 100703836

OAU:	116314581 116335507(kras)

OLA:	100049322(kras) 101154954

OML:	112146394(zgc:55558) 112152425(kras)

CSAI:

133422137(zgc:55558) 133444386(kras)

XMA:	102232995 102233657(kras)

XCO:	114156567(kras) 114160036

XHE:	116733761(kras) 116735593

PRET:

103466102(kras) 103469088

PFOR:

103133675(kras) 103145420

PLAI:

106935770 106951627

PMEI:

106916041(kras) 106931194

GAF:	122822359(zgc:55558) 122836263(kras)

PPRL:

129363290(zgc:55558) 129365107(kras)

CVG:	107095138 107104069(kras)

CTUL:

119781701 119793033(kras)

GMU:	124863530 124864335 124879131(kras)

NFU:	107376655 107388963(kras)

KMR:	108239964(kras) 108243005

ALIM:

106515615(kras) 106528169

NWH:	119416248(kras) 119421583

AOCE:

111563125(kras) 111565328

MCEP:

124997541(zgc:55558) 125014660(kraS)

CSEM:

103380146(kras) 103392975

POV:	109624348(kras) 109641467

SSEN:

122775750 122785922(zgc:55558)

HHIP:

117762987(kras) 117766775(zgc:55558)

HSP:	118109259(kras) 118123859(zgc:55558)

PPLT:

128443999(kras) 128458322(zgc:55558)

SMAU:

118288595(zgc:55558) 118315197(kras)

LCF:	108875379 108881007(zgc:55558)

SDU:	111228455(kras) 111230220

SLAL:

111649083 111655355(kras)

XGL:	120793826(kras) 120806506

HCQ:	109527013 109530437(kras)

SSCV:

125970052 125983169(zgc:55558)

SBIA:

133501700(kras) 133514701(zgc:55558)

PEE:	133403059(kras) 133414337(zgc:55558)

PTAO:

133465751(zgc:55558) 133477772(kras)

BPEC:

110158202 110170289(kras)

MALB:

109958833 109970760(kras)

BSPL:

114856738(kras) 114860848(zgc:55558)

SJO:	128358543(kras) 128378744(zgc:55558)

SASA:

100380437(rask) 106561428 106601908 106606379

STRU:

115152163 115171866 115197360 115207704

OTW:	112218714(kras) 112226270 112252543

OMY:	100136753(p-ras) 100170208(kras) 110487030 110497629

OGO:	124002488(kras) 124020877 124035184

ONE:	115109544 115134119

OKI:	109867582 109877667 109889513

OKE:	118380185(zgc:55558) 118395795(kras) 118401106

SALP:

111952297 111962485 112076192

SNH:	120043786 120054052 120066403(kras)

CCLU:

121532244(kras) 121551578 121577009 123482642

ELS:	105022136(kras) 105029053

SFM:	108926679(kras) 108933921 108941738 114909046

PKI:	111842404 111845660(kras)

AANG:

118216525(zgc:55558) 118218999

LOC:	102696189(kras)

PSPA:

121318385 121319713

ARUT:

117407743 117415640 117419957 117962512

PSEX:

120534191 120542190

LCM:	102352473(KRAS) 102357700

CMK:	103188873 103190146 121852185

RTP:	109919287 109931543

CPLA:

122542641 122561572

HOC:	132826791 132831454

LERI:

129694991 129707662

PMRN:

116956509

LRJ:	133361707 133361975 133362052 133362555 133362592 133362703 133362828

BFO:

118413193

BBEL:

109481866 109484196

SPU:	115918863 578859

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG9375(Ras85D)

DER:

6551803

DSI:	Dsimw501_GD20791(Dsim_Ras85D)

DYA:	Dyak_GE24771

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22599

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:	108368543 108377251

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006054

CPII:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:	105558129 105565359

HST:	105190571 105192124

DQU:

106740784

CFO:

105259246

FEX:

115234907

LHU:	105672246(Ras85D)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

122858226 122858231 122858395

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

692520(Ras1)

MSEX:

115444766

DPL:	KGM_215072

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106677601(Ras85D)

NLU:	111054979 111057721

HVI:	124354699 124367001

MQU:	128982358 128996562 129002395 129002431

PHU:	Phum_PHUM380970

FOC:	113208191 113210919

TPAL:

117642186 117648016

ZNE:	110839079 110839080 110839890

CSEC:

111870385 111875773

SGRE:

126271879 126281415 126324070

BROR:

134527308 134532517

IEL:

124157982

FCD:

110852840

DPX:	DAPPUDRAFT_301818

DMK:

116924867

DPZ:

124321132

PVM:	113821168 113821178

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:	135214307 135214308

HAZT:

108680732

EAF:	111695254 111699153 111716516

LSM:	121122432 121122508

TCF:

131893151

PPOI:

119091385 119091386 119107809

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

106466527 106466770 106473434

CEL:	CELE_ZK792.6(let-60)

CBR:	CBG_06092(Cbr-let-60)

CRQ:	GCK72_014122

NAI:	NECAME_05045 NECAME_05978

BMY:	BM_BM16898(Bma-let-60)

LOA:	LOAG_03928

TSP:

Tsp_07908

HRO:	HELRODRAFT_90797

LGI:	LOTGIDRAFT_104408 LOTGIDRAFT_207643

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115209302 115230002

LJP:

135466256

LAK:

106171253

SMM:	Smp_179910

SHX:	MS3_00005146

OVI:	T265_14106

LLON:

135492058

NVE:	116604984 5504064 5513965 5518427

EPA:

ATEN:

PDAM:

SPIS:

DGT:	114523017 114526249 114544282

XEN:

124453729

HMG:	100209445 100210556 105845433

HSY:

130629027

RES:	135680751 135696767

AQU:

100637745

SCE:	YNL098C(RAS2) YOR101W(RAS1)

SEUB:

DI49_4633 DI49_4939

SPAO:

SPAR_N02130 SPAR_O02360

AGO:	AGOS_ADL262W

ERC:

Ecym_5349

KLA:	KLLA0_C13387g

KMX:	KLMA_80228(RAS2)

LTH:	KLTH0D08932g

VPO:	Kpol_1029p8 Kpol_505p1

ZRO:	ZYRO0B09438g

CGR:	2886566(RAS1)

NCS:	NCAS_0B06850(NCAS0B06850)

NDI:	NDAI_0B04180(NDAI0B04180)

TPF:	TPHA_0B03000(TPHA0B03000)

TBL:	TBLA_0B01750(TBLA0B01750)

TGB:	HG536_0D03450

TDL:	TDEL_0F01360(TDEL0F01360)

KAF:	KAFR_0D02040(KAFR0D02040) KAFR_0J01970(KAFR0J01970)

KNG:	KNAG_0H03380(KNAG0H03380) KNAG_0I01930(KNAG0I01930)

ZMK:	HG535_0A02980

SLUD:

SCDLUD_002914

DHA:	DEHA2F09438g DEHA2G13882g

PIC:	PICST_29006 PICST_44586

PGU:	PGUG_01522

SPAA:

SPAPADRAFT_54778 SPAPADRAFT_67657

LEL:	PVL30_003219(RAS1) PVL30_003508

LBG:	92208744(LODBEIA_P35480) 92208990(LODBEIA_P37940)

CAL:	CAALFM_C210210CA(RAS1) CAALFM_C304480CA(RAS2)

CTP:	CTRG_02064

COT:	CORT_0C03130 CORT_0C06700

CDU:	CD36_24270(RAS1) CD36_84420

CTEN:

18247944(ras1)

CLU:	CLUG_05147

CLUS:

A9F13_01g02420 A9F13_03g00880

CAUR:

CJI96_0001013 CJI96_0002022

PPA:	PAS_chr3_0133 PAS_chr4_0680

PKZ:	C5L36_0A11410 C5L36_0C06230

BNN:	FOA43_000626 FOA43_002407(RAS1)

BBRX:

BRETT_000841

OPA:	HPODL_00707

YLI:	2906948(YALI2_C00474g) 2911447(YALI2_E00600g) 2912500(YALI2_E01586g)

SLB:	AWJ20_3798(RAS2) AWJ20_4884(RAS1)

NCR:	NCU03616(smco-7) NCU08823(bd)

NTE:	NEUTE1DRAFT61565(NEUTE1DRAFT_61565)

SMP:	10801632(SMAC4_09275) 10807016(SMAC4_03107)

PAN:	PODANSg3746 PODANSg7887

PBEL:

QC761_123850(ras1) QC761_201010(ras2)

PPSD:

QC762_123850(ras1) QC762_201010(ras2)

PPSP:

QC763_123850(ras1) QC763_201010(ras2)

PPSA:

QC764_123850(ras1) QC764_201010(ras2)

TTT:	THITE_2106402 THITE_2122749

MTM:	MYCTH_2145069 MYCTH_2300282

CTHR:

CTHT_0039070 CTHT_0051640

MGR:	MGG_06154 MGG_09499

PPEI:

PpBr36_02989 PpBr36_03156

PGRI:

PgNI_01541 PgNI_01714

TMN:	UCRPA7_4593 UCRPA7_5569

SSCK:

SPSK_01789 SPSK_07889

FGR:	FGSG_09778 FGSG_10114

FPU:	FPSE_00865 FPSE_12069(RAS1)

FPOA:

FPOAC1_003198(RAS2) FPOAC1_011863

FVN:	FVRRES_03539 FVRRES_12926

FVR:	FVEG_02837 FVEG_06392

FOX:	FOXG_05293 FOXG_08282

NHE:	NECHADRAFT_41722 NECHADRAFT_66470

FFC:	NCS54_00262800 NCS54_00708900

FKR:	NCS57_00258300 NCS57_00749000

FMU:	J7337_004398 J7337_005748(RAS1)

TRE:	TRIREDRAFT_110960(ras2) TRIREDRAFT_120150(ras1)

TRR:	M419DRAFT_23679 M419DRAFT_88138

TATV:

25781936(TrAtP1_001485) 25783781(TrAtP1_006768)

TASP:

36612248(RAS2) 36617765(TrAFT101_001028)

MAW:	19245666(ras1) 19248127(ras2)

MAJ:	MAA_06380 MAA_11113

MBRN:

26237771(RAS) 26241516(ras-2)

PCHM:

VFPPC_13768 VFPPC_14226

CMT:	CCM_01978 CCM_06996

AMUS:

LMH87_004873 LMH87_011860

PLJ:	28888377(PLICBS_003576) 90642975(PLICBS_004979)

PTKZ:

JDV02_000268(ras1) JDV02_006812(ras2_1) JDV02_010342(ras2_2)

VAL:	VDBG_00306 VDBG_01093

VDA:	VDAG_00701 VDAG_08593

CFJ:	CFIO01_03687 CFIO01_05759

CLUP:

CLUP02_10324 CLUP02_17697

CHIG:

CH63R_09282 CH63R_13985

SAPO:

SAPIO_CDS8386

ELA:	UCREL1_6834

PFY:	PFICI_04757 PFICI_07192 PFICI_12476

SSL:	SS1G_02120 SS1G_03860 SS1G_13801

BFU:	BCIN_04g03140(Bcras2) BCIN_12g05760(Bcras1) BCIN_16g00090

MBE:	MBM_04305 MBM_08084

PSCO:

LY89DRAFT_216856 LY89DRAFT_399553 LY89DRAFT_536512

GLZ:	GLAREA_10571 GLAREA_10616

ANI:	ANIA_00182(rasA) ANIA_05832

AFM:	AFUA_2G07770 AFUA_5G11230

ACT:	ACLA_014270 ACLA_079750

NFI:	NFIA_076050 NFIA_083490

AOR:	AO090003000759 AO090011000918 AO090020000044 AO090026000726

ANG:	An01g02320 An05g00370

AFV:	AFLA_000923 AFLA_005569 AFLA_008311

ALUC:

AKAW2_20421A(RAS1) AKAW2_60733S(RAS2)

ACHE:

ACHE_41111A(RAS1) ACHE_50322S(RAS2)

APUU:

APUU_10840S(RAS2) APUU_11961A(RAS1)

PCS:	N7525_002606 N7525_003647 N7525_007070 N7525_009266

PDP:	PDIP_14290 PDIP_60730

POU:	POX_d05221 POX_f08188

TMF:	EYB26_001771 EYB26_005671

TRG:	TRUGW13939_05571 TRUGW13939_06160 TRUGW13939_11598

CIM:	CIMG_00649 CIMG_00928 CIMG_02066

CPW:	CPC735_045100 CPC735_054150 CPC735_056130

URE:	UREG_00652 UREG_00882

ABE:	ARB_03033 ARB_07694

TVE:	TRV_07268 TRV_07650

PBL:	PAAG_02351 PAAG_08518 PAAG_08855

PBN:	PADG_05282 PADG_05489 PADG_05946

AJE:	HCAG_00894 HCAG_03498 HCAG_07420

BGH:	BDBG_01067 BDBG_08199 BDBG_08975

PNO:	SNOG_03326 SNOG_12045 SNOG_13980

PTE:	PTT_03731 PTT_09539 PTT_10787

PTRR:

6341462(PtrM4_068570) 6347424(PtrM4_036280) 6349869(PtrM4_029410)

BZE:	COCCADRAFT_29560 COCCADRAFT_80731 COCCADRAFT_8777

BSC:	COCSADRAFT_156185 COCSADRAFT_169365 COCSADRAFT_276539

BOR:	COCMIDRAFT_10431 COCMIDRAFT_87281 COCMIDRAFT_9469

AALT:

CC77DRAFT_1011030 CC77DRAFT_510610 CC77DRAFT_947106

ARAB:

EKO05_0000484 EKO05_0009013 EKO05_0011420

ZTR:	MYCGRDRAFT_59862(MgRas1) MYCGRDRAFT_75299(MgRas2) MYCGRDRAFT_76657

PFJ:	MYCFIDRAFT_101280 MYCFIDRAFT_101397 MYCFIDRAFT_58434

FFU:	CLAFUR5_09657 CLAFUR5_11494 CLAFUR5_13013

CBET:

CB0940_06794 CB0940_10388

BCOM:

BAUCODRAFT_298068 BAUCODRAFT_365674 BAUCODRAFT_53363

NPA:	UCRNP2_10198 UCRNP2_2727 UCRNP2_8821

TML:	GSTUM_00002293001 GSTUM_00004380001 GSTUM_00007546001

SPO:	2542285(ras1)

SOM:	SOMG_02653(ras1)

CNE:	CNA02810 CNJ01910

CNB:	CNBA2670 CNBJ1560

CNG:	CNAG_00293 CNAG_04761

CGI:	CGB_B3270C CGB_I2550C

CDEU:

CNBG_0276 CNBG_5602

CDEP:

91087745(L203_103534) 91088756(L203_104546)

KMG:	30161650(I203_107089) 30166209(I203_104090)

KNE:	92178929(IAR55_001670) 92182651(IAR55_005393)

TMS:	TREMEDRAFT_18983 TREMEDRAFT_28995

TASA:

A1Q1_01155 A1Q1_05785

CCAC:

CcaHIS019_0105600(ras1) CcaHIS019_0310560(ras2)

TVS:	TRAVEDRAFT_140206 TRAVEDRAFT_29729

DSQ:	DICSQDRAFT_130749 DICSQDRAFT_133266

PCO:	PHACADRAFT_247072 PHACADRAFT_252796

SHS:	STEHIDRAFT_144457 STEHIDRAFT_46930

HIR:	HETIRDRAFT_413838 HETIRDRAFT_66761

PSQ:	PUNSTDRAFT_101767 PUNSTDRAFT_109796

ADL:	AURDEDRAFT_109795 AURDEDRAFT_112677

FME:	FOMMEDRAFT_102614 FOMMEDRAFT_106970 FOMMEDRAFT_158201

GTR:	GLOTRDRAFT_109227 GLOTRDRAFT_131933 GLOTRDRAFT_46657

RSX:	RhiXN_02169 RhiXN_02765 RhiXN_05719

LBC:	LACBIDRAFT_190576 LACBIDRAFT_254501 LACBIDRAFT_256615 LACBIDRAFT_291884

CCI:	CC1G_04430 CC1G_06445

ABP:	AGABI1DRAFT121109(AGABI1DRAFT_121109) AGABI1DRAFT81209(AGABI1DRAFT_81209)

ABV:	AGABI2DRAFT133440(AGABI2DRAFT_133440) AGABI2DRAFT149467(AGABI2DRAFT_149467)

PCUB:

JR316_0001193 JR316_0006184

MRR:	Moror_212 Moror_9749

E1B28_001329 E1B28_011449

SCM:	SCHCO_02612648(SCHCODRAFT_02612648) SCHCO_02626554(SCHCODRAFT_02626554)

CPUT:

CONPUDRAFT_78775 CONPUDRAFT_88491

SLA:	SERLADRAFT_454853 SERLADRAFT_468264 SERLADRAFT_468266

WSE:	WALSEDRAFT_31345 WALSEDRAFT_60991

WIC:	J056_001311 J056_002256

UMA:	UMAG_00986 UMAG_01643

PFP:	PFL1_01047 PFL1_03687

SGRA:

EX895_002443 EX895_004437 EX895_006214

MGL:

MGL_2669

MRT:

MRET_2663

MSYM:

MSY001_0178

PGR:	PGTG_03066 PGTG_12904

PTRC:

PtA15_16A396 PtA15_1A811

PSTR:

Pst134EA_000275 Pst134EA_032822

MLR:	MELLADRAFT_40575 MELLADRAFT_73486

RIE:	OCT59_010770 OCT59_010771 OCT59_016738 OCT59_030096

MBR:	MONBRDRAFT_38126 MONBRDRAFT_38728 MONBRDRAFT_9855

SRE:	PTSG_05504

DDI:	DDB_G0293434(rasG)

DPP:	DICPUDRAFT_92731(rasG)

DFA:	DFA_07547(rasG)

EHI:	EHI_124520 EHI_124610(42.t00004) EHI_137700(64.t00006)

EDI:	EDI_023960 EDI_024050 EDI_144360 EDI_193960 EDI_275770

ACAN:

ACA1_157500 ACA1_277750

TET:	TTHERM_00412160

PIF:	PITG_03936 PITG_19482

PSOJ:

PHYSODRAFT_356169

SPAR:

SPRG_15092 SPRG_18254

EHX:	EMIHUDRAFT_114652(Ras1-1) EMIHUDRAFT_419127(Ras1-2)

TCR:	504149.110

NGR:	NAEGRDRAFT_60817 NAEGRDRAFT_74704

TVA:	TVAG_2v0076500 TVAG_2v1012170

» show all

Reference

PMID:23698361

Authors

Zimmermann G, Papke B, Ismail S, Vartak N, Chandra A, Hoffmann M, Hahn SA, Triola G, Wittinghofer A, Bastiaens PI, Waldmann H

Title

Small molecule inhibition of the KRAS-PDEdelta interaction impairs oncogenic KRAS signalling.

Journal

Nature 497:638-42 (2013)
DOI:10.1038/nature12205

Reference

PMID:6474169

Authors

Guerrero I, Villasante A, Corces V, Pellicer A

Title

Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation.

Journal

Science 225:1159-62 (1984)
DOI:10.1126/science.6474169

Sequence

[mmu:16653]

All links

Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (176)   
   KEGG PATHWAY (176)   
Disease (28)   
   KEGG DISEASE (28)   
Drug (5)   
   KEGG DRUG (5)   
Gene (7712)   
   KEGG GENES (1400)   
   KEGG MGENES (113)   
   RefGene (6182)   
   OC (17)   
Literature (2)   
   PubMed (2)   
All databases (7927)   

Download RDF

ORTHOLOGY: K02833

Entry

K02833                      KO

Symbol

HRAS

Name

GTPase HRas

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map01522

Endocrine resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04062

Chemokine signaling pathway

map04068

FoxO signaling pathway

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04137

Mitophagy - animal

map04140

Autophagy - animal

map04144

Endocytosis

map04150

mTOR signaling pathway

map04151

PI3K-Akt signaling pathway

map04210

Apoptosis

map04211

Longevity regulating pathway

map04213

Longevity regulating pathway - multiple species

map04218

Cellular senescence

map04360

Axon guidance

map04370

VEGF signaling pathway

map04371

Apelin signaling pathway

map04510

Focal adhesion

map04540

Gap junction

map04550

Signaling pathways regulating pluripotency of stem cells

map04625

C-type lectin receptor signaling pathway

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04660

T cell receptor signaling pathway

map04662

B cell receptor signaling pathway

map04664

Fc epsilon RI signaling pathway

map04714

Thermogenesis

map04720

Long-term potentiation

map04722

Neurotrophin signaling pathway

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04730

Long-term depression

map04810

Regulation of actin cytoskeleton

map04910

Insulin signaling pathway

map04912

GnRH signaling pathway

map04915

Estrogen signaling pathway

map04916

Melanogenesis

map04917

Prolactin signaling pathway

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04926

Relaxin signaling pathway

map04929

GnRH secretion

map04933

AGE-RAGE signaling pathway in diabetic complications

map04935

Growth hormone synthesis, secretion and action

map05010

Alzheimer disease

map05022

Pathways of neurodegeneration - multiple diseases

map05034

Alcoholism

map05132

Salmonella infection

map05160

Hepatitis C

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05170

Human immunodeficiency virus 1 infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05208

Chemical carcinogenesis - reactive oxygen species

map05210

Colorectal cancer

map05211

Renal cell carcinoma

map05213

Endometrial cancer

map05214

Glioma

map05215

Prostate cancer

map05216

Thyroid cancer

map05218

Melanoma

map05219

Bladder cancer

map05220

Chronic myeloid leukemia

map05221

Acute myeloid leukemia

map05223

Non-small cell lung cancer

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05230

Central carbon metabolism in cancer

map05231

Choline metabolism in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05417

Lipid and atherosclerosis

Disease

H00022

Bladder cancer

H00025

Penile cancer

H00030

Cervical cancer

H00032

Thyroid cancer

H00040

Squamous cell carcinoma

H00523

Noonan syndrome and related disorders

H01470

Giant cell tumor of bone

H01555

Merkel cell carcinoma

H01592

Medullary thyroid cancer

H01666

Angiosarcoma

H01747

Costello syndrome

H02627

Epidermal nevus

H02628

Schimmelpenning-Feuerstein-Mims syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K02833  HRAS; GTPase HRas
   04012 ErbB signaling pathway
    K02833  HRAS; GTPase HRas
   04014 Ras signaling pathway
    K02833  HRAS; GTPase HRas
   04015 Rap1 signaling pathway
    K02833  HRAS; GTPase HRas
   04370 VEGF signaling pathway
    K02833  HRAS; GTPase HRas
   04371 Apelin signaling pathway
    K02833  HRAS; GTPase HRas
   04630 JAK-STAT signaling pathway
    K02833  HRAS; GTPase HRas
   04068 FoxO signaling pathway
    K02833  HRAS; GTPase HRas
   04072 Phospholipase D signaling pathway
    K02833  HRAS; GTPase HRas
   04071 Sphingolipid signaling pathway
    K02833  HRAS; GTPase HRas
   04151 PI3K-Akt signaling pathway
    K02833  HRAS; GTPase HRas
   04150 mTOR signaling pathway
    K02833  HRAS; GTPase HRas
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K02833  HRAS; GTPase HRas
   04140 Autophagy - animal
    K02833  HRAS; GTPase HRas
   04137 Mitophagy - animal
    K02833  HRAS; GTPase HRas
  09143 Cell growth and death
   04210 Apoptosis
    K02833  HRAS; GTPase HRas
   04218 Cellular senescence
    K02833  HRAS; GTPase HRas
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K02833  HRAS; GTPase HRas
   04540 Gap junction
    K02833  HRAS; GTPase HRas
   04550 Signaling pathways regulating pluripotency of stem cells
    K02833  HRAS; GTPase HRas
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K02833  HRAS; GTPase HRas
09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K02833  HRAS; GTPase HRas
   04650 Natural killer cell mediated cytotoxicity
    K02833  HRAS; GTPase HRas
   04660 T cell receptor signaling pathway
    K02833  HRAS; GTPase HRas
   04662 B cell receptor signaling pathway
    K02833  HRAS; GTPase HRas
   04664 Fc epsilon RI signaling pathway
    K02833  HRAS; GTPase HRas
   04062 Chemokine signaling pathway
    K02833  HRAS; GTPase HRas
  09152 Endocrine system
   04910 Insulin signaling pathway
    K02833  HRAS; GTPase HRas
   04929 GnRH secretion
    K02833  HRAS; GTPase HRas
   04912 GnRH signaling pathway
    K02833  HRAS; GTPase HRas
   04915 Estrogen signaling pathway
    K02833  HRAS; GTPase HRas
   04917 Prolactin signaling pathway
    K02833  HRAS; GTPase HRas
   04921 Oxytocin signaling pathway
    K02833  HRAS; GTPase HRas
   04926 Relaxin signaling pathway
    K02833  HRAS; GTPase HRas
   04935 Growth hormone synthesis, secretion and action
    K02833  HRAS; GTPase HRas
   04919 Thyroid hormone signaling pathway
    K02833  HRAS; GTPase HRas
   04916 Melanogenesis
    K02833  HRAS; GTPase HRas
  09156 Nervous system
   04725 Cholinergic synapse
    K02833  HRAS; GTPase HRas
   04726 Serotonergic synapse
    K02833  HRAS; GTPase HRas
   04720 Long-term potentiation
    K02833  HRAS; GTPase HRas
   04730 Long-term depression
    K02833  HRAS; GTPase HRas
   04722 Neurotrophin signaling pathway
    K02833  HRAS; GTPase HRas
  09158 Development and regeneration
   04360 Axon guidance
    K02833  HRAS; GTPase HRas
  09149 Aging
   04211 Longevity regulating pathway
    K02833  HRAS; GTPase HRas
   04213 Longevity regulating pathway - multiple species
    K02833  HRAS; GTPase HRas
  09159 Environmental adaptation
   04714 Thermogenesis
    K02833  HRAS; GTPase HRas
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02833  HRAS; GTPase HRas
   05206 MicroRNAs in cancer
    K02833  HRAS; GTPase HRas
   05205 Proteoglycans in cancer
    K02833  HRAS; GTPase HRas
   05207 Chemical carcinogenesis - receptor activation
    K02833  HRAS; GTPase HRas
   05208 Chemical carcinogenesis - reactive oxygen species
    K02833  HRAS; GTPase HRas
   05203 Viral carcinogenesis
    K02833  HRAS; GTPase HRas
   05230 Central carbon metabolism in cancer
    K02833  HRAS; GTPase HRas
   05231 Choline metabolism in cancer
    K02833  HRAS; GTPase HRas
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K02833  HRAS; GTPase HRas
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02833  HRAS; GTPase HRas
   05225 Hepatocellular carcinoma
    K02833  HRAS; GTPase HRas
   05226 Gastric cancer
    K02833  HRAS; GTPase HRas
   05214 Glioma
    K02833  HRAS; GTPase HRas
   05216 Thyroid cancer
    K02833  HRAS; GTPase HRas
   05221 Acute myeloid leukemia
    K02833  HRAS; GTPase HRas
   05220 Chronic myeloid leukemia
    K02833  HRAS; GTPase HRas
   05218 Melanoma
    K02833  HRAS; GTPase HRas
   05211 Renal cell carcinoma
    K02833  HRAS; GTPase HRas
   05219 Bladder cancer
    K02833  HRAS; GTPase HRas
   05215 Prostate cancer
    K02833  HRAS; GTPase HRas
   05213 Endometrial cancer
    K02833  HRAS; GTPase HRas
   05224 Breast cancer
    K02833  HRAS; GTPase HRas
   05223 Non-small cell lung cancer
    K02833  HRAS; GTPase HRas
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02833  HRAS; GTPase HRas
   05170 Human immunodeficiency virus 1 infection
    K02833  HRAS; GTPase HRas
   05161 Hepatitis B
    K02833  HRAS; GTPase HRas
   05160 Hepatitis C
    K02833  HRAS; GTPase HRas
   05163 Human cytomegalovirus infection
    K02833  HRAS; GTPase HRas
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02833  HRAS; GTPase HRas
   05165 Human papillomavirus infection
    K02833  HRAS; GTPase HRas
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K02833  HRAS; GTPase HRas
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02833  HRAS; GTPase HRas
   05022 Pathways of neurodegeneration - multiple diseases
    K02833  HRAS; GTPase HRas
  09165 Substance dependence
   05034 Alcoholism
    K02833  HRAS; GTPase HRas
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K02833  HRAS; GTPase HRas
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02833  HRAS; GTPase HRas
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K02833  HRAS; GTPase HRas
   01522 Endocrine resistance
    K02833  HRAS; GTPase HRas
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K02833  HRAS; GTPase HRas
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K02833  HRAS; GTPase HRas
   04031 GTP-binding proteins
    K02833  HRAS; GTPase HRas
Membrane trafficking [BR:ko04131]
Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    K02833  HRAS; GTPase HRas
Endocytosis
  Macropinocytosis
   Ras GTPases
    K02833  HRAS; GTPase HRas
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K02833  HRAS; GTPase HRas
  Exosomal proteins of colorectal cancer cells
   K02833  HRAS; GTPase HRas
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    K02833  HRAS; GTPase HRas

Genes

HSA:	3265(HRAS)

PTR:	466302(HRAS)

PPS:	100993386(HRAS)

GGO:	101136425(HRAS)

PON:	100459427(HRAS)

PPYG:

129007179(HRAS)

NLE:	100595274(HRAS)

HMH:	116466571(HRAS)

SSYN:

129471483(HRAS)

MCC:	698830(HRAS)

MCF:	102118744(HRAS)

MTHB:

126935869

MNI:	105494134(HRAS)

CSAB:

103246363(HRAS)

CATY:

105577198(HRAS)

PANU:

101002992(HRAS)

TGE:	112607359(HRAS)

MLEU:

105549333(HRAS)

RRO:	104654600(HRAS)

RBB:	108543525(HRAS)

TFN:	117081688(HRAS)

CANG:

105503192(HRAS)

CJC:	100406017(HRAS)

SBQ:	101047663(HRAS)

CIMI:

108288791(HRAS)

ANAN:

105719851(HRAS)

CSYR:

103250130(HRAS)

MMUR:

105874032(HRAS)

LCAT:

123642937(HRAS)

PCOQ:

105816561(HRAS)

OGA:	100951644(HRAS)

MMU:	15461(Hras)

MCAL:

110297313(Hras)

MPAH:

110318967 110319567(Hras) 110333346 110338480

RNO:	293621(Hras) 367858(Hrasl1)

ANU:	117706664(Hras)

MUN:	110553931(Hras)

CGE:	100773737(Hras)

MAUA:

101838968(Hras)

PROB:

127228530(Hras)

PLEU:

114685127 114688488 114693493 114693595(Hras) 114696553

MORG:

121458090(Hras)

MFOT:

126498807

AAMP:

119800249(Hras)

NGI:	103751075(Hras)

HGL:	101716053(Hras)

CPOC:

100735038(Hras)

CCAN:

109698042(Hras)

DORD:

105998617(Hras)

DSP:	122095011(Hras)

PLOP:

125362333(Hras)

NCAR:

124958599

MMMA:

107157108(Hras)

OCU:

127486605

OPI:	101531636(HRAS)

TUP:	102493230(HRAS)

GVR:	103610513(HRAS)

CFA:	403735(HRAS)

CLUD:

112663536(HRAS)

VVP:	112914428(HRAS)

VLG:	121472124(HRAS)

NPO:	129494224(HRAS)

AML:	100473836(HRAS)

UMR:	103669173 103671035(HRAS)

UAH:	125282300(HRAS)

UAR:	123775506(HRAS)

ELK:

111140316

LLV:

125078621

MPUF:

101681355(HRAS)

MNP:	132016391(HRAS) 132027717

MLK:	131818337(HRAS)

NVS:	122913220(HRAS)

ORO:	101367134 101372786(HRAS)

EJU:	114201560(HRAS)

ZCA:	113914876(HRAS)

MLX:	118016228(HRAS)

NSU:	110582206(HRAS) 123323805

LWW:	102735541(HRAS) 115936553

FCA:	751103(HRAS)

PYU:	121022826(HRAS)

PBG:	122484176(HRAS)

PVIV:

125146782(HRAS)

LRUF:

124527565

PTG:	102952119(HRAS)

PPAD:

109259759

PUC:

125937753

AJU:

106987957

HHV:	120223392(HRAS)

BTA:	100298939(HRAS) 100847184

BOM:	102277011(HRAS) 102278591

BIU:

109560940

BBUB:

112587129

BBIS:

105003692(HRAS)

CHX:	102186668(HRAS)

OAS:	101104357(HRAS) 114114919

BTAX:

128068689(HRAS)

ODA:	120874214(HRAS)

CCAD:

122430591(HRAS)

MBEZ:

129548597(HRAS)

SSC:	110259208(HRAS)

CFR:	102524334(HRAS)

CBAI:

105069943(HRAS)

CDK:	105105427(HRAS)

VPC:	102525363(HRAS)

BACU:

103006545(HRAS)

BMUS:

118892044 118899209(HRAS)

LVE:	103076043(HRAS)

OOR:	101271947 101286301(HRAS)

DLE:	111170340(HRAS)

PCAD:

102994715(HRAS)

PSIU:

116751649 116757893(HRAS)

NASI:

112402519(HRAS)

ECB:	100055481(HRAS)

EPZ:	103567332(HRAS)

EAI:	106824973(HRAS)

MYB:	102263667(HRAS)

MYD:	102762537(HRAS)

MMYO:

118648965(HRAS)

MDT:	132241831(HRAS)

PKL:	118717957(HRAS)

EFUS:

103302548(HRAS)

MNA:	107542351(HRAS)

DRO:	112317099(HRAS)

SHON:

118982230(HRAS)

AJM:	119062206(HRAS)

PDIC:

114499504(HRAS)

PHAS:

123807317(HRAS)

MMF:	118643162(HRAS)

PPAM:

129073113(HRAS)

HAI:	109375639(HRAS) 109385150

RFQ:	117013636 117029835(HRAS)

PALE:

102896270(HRAS)

PGIG:

120584662(HRAS)

PVP:	105305933(HRAS)

RAY:	107507127(HRAS)

MJV:	108408627(HRAS) 118967667

TOD:	119249824(HRAS)

SARA:

101546777(HRAS)

SETR:

126019084(HRAS)

TMU:

101342804

ETF:	101663997(HRAS)

DNM:	101419480(HRAS)

MDO:	100032921(HRAS)

SHR:	100929168 116419913(HRAS)

AFZ:

127540068

PCW:	110202954(HRAS)

TVP:	118851647 118853447(HRAS)

OAA:	114809992(HRAS)

GGA:	396229(HRAS)

PCOC:

116239023(HRAS)

MGP:	100546858(HRAS)

CJO:	107314494(HRAS)

TPAI:

128086364(HRAS)

LMUT:

125694448(HRAS)

NMEL:

110400761(HRAS)

APLA:

101793649(HRAS)

ACYG:

106031749(HRAS)

CATA:

118250718(HRAS)

AFUL:

116490064(HRAS)

TGU:	100190361(HRAS)

LSR:

110484448

SCAN:

103824084(HRAS)

PMOA:

120511367(HRAS)

OTC:	121344866(HRAS)

PRUF:

121360994(HRAS)

GFR:	102044012(HRAS)

FAB:	101811520(HRAS)

OMA:	130253414(HRAS)

PHI:	102101219(HRAS)

PMAJ:

107205559(HRAS)

CCAE:

111930717(HRAS)

CCW:	104691739(HRAS)

CBRC:

103620698(HRAS)

ETL:	114064818(HRAS)

ZAB:	102070663(HRAS)

ZLE:	135448519(HRAS)

ACHL:

103801883(HRAS)

SVG:	106851547(HRAS)

MMEA:

130576649(HRAS)

HRT:	120753590(HRAS)

SATI:

136362475(HRAS)

FPG:	101916982(HRAS)

FCH:	102055506(HRAS)

CCRI:

104158389(HRAS)

NNT:	104412858(HRAS)

SHAB:

115607639(HRAS)

ACUN:

113481169(HRAS)

TALA:

104365067(HRAS)

ACHC:

115351819(HRAS)

HALD:

104317684(HRAS)

HLE:	104828686(HRAS)

AGEN:

126047240

GCL:

127016479

CSTI:

104559677(HRAS)

LDI:	104354294(HRAS)

MNB:	103769106 103776418

DPUB:

104305653

AVIT:

104273878

BRHI:

104494437(HRAS)

EGZ:	104123569(HRAS)

NNI:	104017304(HRAS)

PCRI:

104033574(HRAS)

PCAO:

104044440(HRAS)

PADL:

103916453(HRAS)

AFOR:

103896209(HRAS)

FGA:

104073353

GSTE:

104254756(HRAS)

CLV:	102091763(HRAS)

MUI:

104544529

PGUU:

104459366

PLET:

104623545(HRAS)

EHS:	104507894(HRAS)

CMAC:

104487373(HRAS)

CUCA:

104068924(HRAS)

TEO:

104373936

BREG:

104631064(HRAS)

OHA:	104335340(HRAS)

CPEA:

104387643(HRAS)

CVF:	104290283(HRAS)

RTD:	128908943(HRAS)

AAM:	106494862(HRAS)

AROW:

112962697(HRAS)

NPD:	112943529(HRAS)

TGT:	104575482(HRAS)

DNE:	112987947(HRAS)

SCAM:

104143715(HRAS)

ASN:	102380807(HRAS)

AMJ:	102562157(HRAS)

CPOO:

109318199(HRAS)

GGN:	109299228(HRAS)

PSS:	102457627(HRAS)

CMY:	102946454(HRAS)

CCAY:

125637699(HRAS)

DCC:	119857099(HRAS)

CPIC:

101937663(HRAS)

TST:	117877347(HRAS)

CABI:

116820748(HRAS)

MRV:	120405072(HRAS)

ACS:	100565678(hras)

ASAO:

132771520(HRAS)

PVT:	110074175(HRAS)

SUND:

121926328(HRAS)

PBI:	103065743(HRAS)

PMUR:

107287923(HRAS)

CTIG:

120302590(HRAS)

TSR:	106544570(HRAS)

PGUT:

117665176(HRAS)

APRI:

131184917(HRAS)

PTEX:

113440320(HRAS)

NSS:	113412507(HRAS)

VKO:	123021252(HRAS)

PMUA:

114599845(HRAS)

PRAF:

128417124(HRAS)

ZVI:	118088586(HRAS)

HCG:	128340461(HRAS)

GJA:	107112057(HRAS)

STOW:

125426937(HRAS)

EMC:	129324311(HRAS)

XLA:	399406(hras.L)

XTR:	549757(hras)

NPR:	108786689(HRAS)

RTEM:

120917364(HRAS)

BBUF:

120981053(HRAS)

BGAR:

122920728(HRAS)

MUO:	115469027(HRAS)

GSH:	117352400(HRAS)

DRE:	550286(hrasa) 553656(hrasb)

SRX:	107707549 107709950 107735603 107757516

SANH:

107675296 107675668 107695370 107696631

SGH:	107558311 107562835 107596435 107600445

CCAR:

109047565 109062366 109062821 109070813

CAUA:

113043599 113051345 113067303 113106249

CGIB:

127946728 127961820 128013758 128016609

PTET:

122331115(hrasa) 122349499(hrasb)

LROH:

127156808(hrasa) 127168650(hrasb)

OMC:	131534047(hrasa) 131543828(hrasb)

PPRM:

120464885(hrasb) 120473360(hrasa)

RKG:	130086014(hrasa) 130091247(hrasb)

MAMB:

125247376(hrasa) 125265127(hrasb)

CIDE:

127507367 127516364

CERY:

137014687(hrasa) 137031219(hrasb)

MASI:

127436084 127437085 127443565 127452252

TROS:

130551615(hrasa) 130554426(hrasb)

TDW:	130414027(hrasa) 130419842(hrasb)

MANU:

129434004(hrasa) 129447448(hrasb)

IPU:	100528230(hrasa) 108259582(hrasb)

IFU:	128602959(hrasb) 128618140(hrasa)

PHYP:

113529824 113540939

SMEO:

124379989(hrasb) 124392405(hrasa)

TFD:	113636822(hrasb) 113660166(hrasa)

TVC:	132838753(hrasb) 132856833(hrasa)

TRN:	134303898(hrasb) 134309477(hrasa)

AMEX:

103021516(hrasa) 103040103(hrasb)

CMAO:

118811525(hrasa) 118817540(hrasb)

EEE:	113579694 113581312(hras)

CHAR:

105892655 105908806(hrasa)

TRU:	101079899(hras)

TFS:	130536738(hrasa)

TNG:	GSTEN00003165G001 GSTEN00021499G001

LCO:	104920460(hras)

NCC:	104948001(hras)

TBEN:

117491619(hrasb)

CGOB:

115009535(hras)

PGEO:

117448041(hrasb)

GACU:

117545900

EMAC:

134876142(hrasb)

ELY:

117262369

EFO:

125887517

PLEP:

121949870(hrasb)

SLUC:

116038742

ECRA:

117949110(hrasb)

ESP:	116694245(hras)

PFLV:

114559784(hras)

GAT:	120808880 120812270

PPUG:

119196409

AFB:

129108847

CLUM:

117732119(hrasb)

PSWI:

130195891

MSAM:

119893575(hrasb)

SCHU:

122875107

CUD:

121514905

ALAT:

119024444

MZE:	101474892(hras)

ONL:	100706358(hras)

OAU:

116333285

OLA:	101165278(hras)

OML:	112151792(hrasa)

CSAI:

133444043(hrasa)

XMA:	102217290(hras)

XCO:	114135737(hras)

XHE:	116734025(hras)

PRET:

103466143(hras)

PFOR:

103151608 103151612(hras)

PLAI:

106953713(hras)

PMEI:

106917342(hras)

GAF:	122835505(hrasb)

PPRL:

129361070

CVG:	107085426(hras)

CTUL:

119776860

GMU:

124882413

NFU:	107389003(hras)

KMR:

108239982

ALIM:

106515650(hras)

NWH:

119416207

AOCE:

111584369(hras)

MCEP:

125015016

CSEM:

103380387(hras)

POV:	109638968(hras)

SSEN:

122775945

HHIP:

117763573

HSP:	118109904(hrasb)

PPLT:

128444184

SMAU:

118315960(hrasb)

LCF:

108875409

SDU:	111228382(hras)

SLAL:

111661823(hras)

XGL:

120792735

HCQ:	109530360(hras)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110169298(hras)

MALB:

109970774(hras)

BSPL:

114857388

SJO:	128359229(hrasa)

SASA:

100196603(rash) 106573361

STRU:

115152114 115197299

OTW:	112218668 112252501

OMY:	110496976 110522187

OGO:	124002027 124035796

ONE:	115109509 115134169(hras)

OKI:	109867777 109889479

OKE:	118370933 118395741

SALP:

111952380 111962576

SNH:	120054020 120066370

CCLU:

121532188 121576390

ELS:	105018344(hras)

SFM:	108934636 108942359(hras)

PKI:	111840699 111859528(hras)

AANG:

118215356 118227896

LOC:	102697398(hras)

PSPA:

121294911 121330312(hrasb)

ARUT:

117431924 117434435

PSEX:

120523258

LCM:	102355427(HRAS)

CMK:	103189080 121852244

RTP:

109915744

CPLA:

122557741

HOC:

132824459

LERI:

129705671(kras)

PMRN:

116945466

LRJ:

133351533

CVS:

136989489

PMEO:

129581453 129588395 129590830

BGT:

106054683

OVI:	T265_13175

EGL:

EGR_06185

SPIS:

111341081

TAD:	TRIADDRAFT_29518

VG:	37618879(D1R95_gp2) 37618880(D1R95_gp1)

» show all

Reference

PMID:8922043

Authors

Przybojewska B, Plucienniczak G

Title

Nucleotide sequence of c-H-ras-1 gene from B6C3F1 mice.

Journal

Acta Biochim Pol 43:575-8 (1996)

Sequence

[mmu:15461]

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