KEGG   ORTHOLOGY: K07868
Entry
K07868                      KO                                     

Name
RHOBTB1_2
Definition
Rho-related BTB domain-containing protein 1/2
Pathway
ko04120  Ubiquitin mediated proteolysis
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoBTB
    K07868  RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
Genes
HSA: 23221(RHOBTB2) 9886(RHOBTB1)
PTR: 450482(RHOBTB1) 464050(RHOBTB2)
PPS: 100972407(RHOBTB2) 100995265(RHOBTB1)
GGO: 109024873(RHOBTB2) 109025381(RHOBTB1)
PON: 100174455(RHOBTB2) 100294551(RHOBTB1)
NLE: 100584666(RHOBTB1) 100602112(RHOBTB2)
MCC: 699132(RHOBTB1) 716607(RHOBTB2)
MCF: 101925744(RHOBTB1) 102134397(RHOBTB2)
CSAB: 103215466(RHOBTB2) 103216144(RHOBTB1)
RRO: 104663680(RHOBTB1) 104663982(RHOBTB2)
RBB: 108517521(RHOBTB1) 108540790(RHOBTB2)
CJC: 100407365(RHOBTB1) 100414447(RHOBTB2)
SBQ: 101035271(RHOBTB1) 101048268(RHOBTB2)
MMU: 246710(Rhobtb2) 69288(Rhobtb1)
MCAL: 110302863(Rhobtb1) 110309139(Rhobtb2)
MPAH: 110325494(Rhobtb2) 110326282(Rhobtb1)
RNO: 306004(Rhobtb2) 309722(Rhobtb1)
CGE: 100767011(Rhobtb1) 100770205(Rhobtb2)
NGI: 103737469(Rhobtb1) 103747978(Rhobtb2)
HGL: 101696728(Rhobtb2) 101716321(Rhobtb1)
CCAN: 109689703(Rhobtb2) 109695111(Rhobtb1)
OCU: 100345646(RHOBTB2) 100352605(RHOBTB1)
TUP: 102470624(RHOBTB2) 102490724(RHOBTB1)
CFA: 100856331(RHOBTB2) 488998(RHOBTB1)
VVP: 112926810(RHOBTB2) 112931040(RHOBTB1)
AML: 100476537(RHOBTB2) 100477541(RHOBTB1)
UMR: 103667742(RHOBTB1) 103673311(RHOBTB2)
UAH: 113259077(RHOBTB1) 113269988(RHOBTB2)
ORO: 101362742(RHOBTB2) 101369145(RHOBTB1)
FCA: 101080740(RHOBTB1) 101085882(RHOBTB2)
PTG: 102952680(RHOBTB2) 102970002(RHOBTB1)
PPAD: 109264296(RHOBTB1) 109277334(RHOBTB2)
AJU: 106981114(RHOBTB2) 106989883(RHOBTB1)
BTA: 540513(RHOBTB1) 784567(RHOBTB2)
BOM: 102276450(RHOBTB1)
BBUB: 102394479(RHOBTB2) 102406070 102415941(RHOBTB1)
CHX: 100861107(RHOBTB1) 102190957(RHOBTB2)
OAS: 101120983(RHOBTB1) 443007(RHOBTB2)
SSC: 100152436(RHOBTB2) 100153330(RHOBTB1)
CFR: 102504736(RHOBTB2) 102511812(RHOBTB1)
CDK: 105093853(RHOBTB1) 105102525(RHOBTB2)
BACU: 103005024(RHOBTB2) 103013950(RHOBTB1)
LVE: 103073568(RHOBTB2) 103091530(RHOBTB1)
OOR: 101271707(RHOBTB1) 101274108(RHOBTB2)
DLE: 111167595(RHOBTB1) 111169005(RHOBTB2)
PCAD: 102987897(RHOBTB1) 114486909(RHOBTB2)
ECB: 100057764(RHOBTB2) 100062805(RHOBTB1)
EPZ: 103552763(RHOBTB2) 103559221(RHOBTB1)
EAI: 106826167(RHOBTB1) 106847701(RHOBTB2)
MYB: 102246424(RHOBTB1) 102253672(RHOBTB2)
MYD: 102752250(RHOBTB2) 102760225(RHOBTB1)
MNA: 107536103(RHOBTB2) 107543324(RHOBTB1)
HAI: 109375966(RHOBTB2) 109380627(RHOBTB1)
DRO: 112305189(RHOBTB2) 112305596(RHOBTB1)
PALE: 102879621(RHOBTB2) 102885346(RHOBTB1)
RAY: 107501468(RHOBTB1) 107509217(RHOBTB2)
MJV: 108393206(RHOBTB2) 108404732(RHOBTB1)
LAV: 100663419(RHOBTB2) 100669185(RHOBTB1)
MDO: 100018851(RHOBTB1) 100030651(RHOBTB2)
SHR: 100917992(RHOBTB2) 100923897(RHOBTB1)
PCW: 110200402(RHOBTB2) 110216375(RHOBTB1)
OAA: 100075048(RHOBTB2) 100077703(RHOBTB1)
GGA: 107056274 419536(RHOBTB2) 423664(RHOBTB1)
MGP: 100543643(RHOBTB2) 100550445(RHOBTB1)
CJO: 107306825 107315681(RHOBTB1) 107323673(RHOBTB2)
NMEL: 110387164(RHOBTB2) 110390960 110399723(RHOBTB1)
APLA: 101800229(RHOBTB1)
ACYG: 106031406(RHOBTB1) 106049701(RHOBTB2)
TGU: 100219969(RHOBTB2) 100226077(RHOBTB1) 115494853
LSR: 110468730 110473040(RHOBTB1) 110480331(RHOBTB2)
SCAN: 103814058(RHOBTB1) 103824424(RHOBTB2)
GFR: 102034068(RHOBTB1) 102041252(RHOBTB2)
FAB: 101811746 101816605(RHOBTB2) 101821602(RHOBTB1)
PHI: 102102178 102104814(RHOBTB1) 102108355(RHOBTB2)
PMAJ: 107198927 107206656(RHOBTB1) 107213951(RHOBTB2)
CCAE: 111931550(RHOBTB1) 111938817(RHOBTB2)
CCW: 104690172(RHOBTB1) 104694880(RHOBTB2) 120409949
ETL: 114063891(RHOBTB1) 114069859(RHOBTB2) 114071793
FPG: 101911153(RHOBTB2) 101912744(RHOBTB1) 101924848
FCH: 102057567(RHOBTB2) 102058757(RHOBTB1)
CLV: 102083944(RHOBTB1) 102091709(RHOBTB2)
EGZ: 104123535(RHOBTB2) 104124645(RHOBTB1)
NNI: 104013462(RHOBTB1) 104019530(RHOBTB2)
ACUN: 113481932(RHOBTB1)
PADL: 103913110(RHOBTB2) 103918505(RHOBTB1)
AAM: 106485708(RHOBTB2) 106486979(RHOBTB1)
ASN: 102374327(RHOBTB2) 102375427 102385593(RHOBTB1)
AMJ: 102568902(RHOBTB2) 102577314 106737181(RHOBTB1)
PSS: 102448449(RHOBTB1) 102459279(RHOBTB2)
CMY: 102930533 102938451(RHOBTB1) 102943370(RHOBTB2)
CPIC: 101932902 101939254(RHOBTB1) 101945156(RHOBTB2)
ACS: 100558177 100562439(rhobtb1) 100567103(rhobtb2)
PVT: 110072185(RHOBTB2) 110079818 110090862(RHOBTB1)
PBI: 103055893(RHOBTB2) 103058021(RHOBTB1) 103063534
PMUR: 107295864 107297331(RHOBTB1) 107299235(RHOBTB2) 107301020
TSR: 106538916 106549231(RHOBTB1) 106556310(RHOBTB2)
PMUA: 114585365(RHOBTB2) 114597160(RHOBTB1) 114598052
GJA: 107107292(RHOBTB2) 107114754(RHOBTB1) 107117626
XLA: 108696080(rhobtb1.L) 108704855 108706470 108711624(rhobtb2.L) 108712692(rhobtb2.S) 444105(rhobtb1.S)
XTR: 100038184(rhobtb1) 100144291(rhobtb2) 116408406
NPR: 108792830(RHOBTB2) 108801174 108804794(RHOBTB1)
DRE: 100537290(rhobtb1) 553415(rhobtb4) 565844(rhobtb2b) 792631(si:dkey-263f15.2)
IPU: 108255835 108266035(rhobtb2) 108273459(rhobtb1)
PHYP: 113527753(rhobtb1) 113533297(rhobtb2) 113536916
AMEX: 103021786 103022493(rhobtb1) 103034624(rhobtb2)
EEE: 113577030(rhobtb1) 113578167(rhobtb2) 113580498
TRU: 101073498(rhobtb2)
LCO: 104918085 104931153(rhobtb2)
NCC: 104951955 104965044(rhobtb2)
MZE: 101470080 101471930(rhobtb2)
ONL: 100706307(rhobtb2) 100707935
OLA: 101161977 101172825(rhobtb2)
XMA: 102234696 102235838(rhobtb2)
XCO: 114154544 114154600(rhobtb2)
PRET: 103470451 103470504(rhobtb2)
CVG: 107084546 107093856(rhobtb2)
NFU: 107393762(rhobtb2) 107393854
KMR: 108236574 108242833(rhobtb4)
ALIM: 106532562(rhobtb2) 106534802
AOCE: 111578647(rhobtb2) 111583603
CSEM: 103398230(rhobtb2)
POV: 109633603(rhobtb2) 109633810
LCF: 108878231 108878492(rhobtb2)
SDU: 111226638 111230789(rhobtb2)
SLAL: 111651575 111663939(rhobtb2)
HCQ: 109525359(rhobtb2) 109530709
BPEC: 110164577 110169913(rhobtb2)
MALB: 109956907(rhobtb2) 109956932
SFM: 108925057 108929453(rhobtb2) 108932784 108938624(rhobtb3) 108939451(rhobtb1)
PKI: 111838933(rhobtb2) 111847069 111847281 111853732(rhobtb1)
LCM: 102358015 102365356(RHOBTB1) 102365816(RHOBTB2)
CMK: 103180966(rhobtb1) 103190310(rhobtb2)
RTP: 109910405(rhobtb2) 109911523(rhobtb1) 109913732
CIN: 100185717
APLC: 110977126
DME: Dmel_CG5701(RhoBTB)
DER: 6544554
DSE: 6616290
DSI: Dsimw501_GD14882(Dsim_GD14882)
DAN: 6493207
DSR: 110184659
DPE: 6603354
DMN: 108152652
DWI: 6638787
DNV: 115564175
DHE: 111592254
DVI: 6624527
MDE: 101899396
LCQ: 111682683
AAG: 5564816
AME: 413034
BIM: 100742731
BTER: 100645778
CCAL: 108628763
OBB: 114876796
SOC: 105199617
MPHA: 105835517
AEC: 105145958
ACEP: 105623402
PBAR: 105432427
VEM: 105563851
HST: 105183645
DQU: 106741754
CFO: 105256241
LHU: 105672522
PGC: 109855173
OBO: 105278927
PCF: 106786771
NVI: 100120104
CSOL: 105367895
MDL: 103569961
TCA: 661174
DPA: 109542044
NVL: 108561226
BMOR: 105841626
BMAN: 114253057
PMAC: 106719046
PRAP: 110994090
HAW: 110381093
TNL: 113498936
BTAB: 109039295
CLEC: 106668406
ZNE: 110839233
FCD: 110856644
DPTE: 113788563
CSCU: 111618480
PCAN: 112563647
OBI: 106872317
DGT: 114516371
HMG: 100202873
 » show all
Reference
  Authors
Berthold J, Schenkova K, Ramos S, Miura Y, Furukawa M, Aspenstrom P, Rivero F
  Title
Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism.
  Journal
Exp Cell Res 314:3453-65 (2008)
DOI:10.1016/j.yexcr.2008.09.005
  Sequence
[hsa:9886 23221]

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