KEGG   ORTHOLOGY: K07936
Entry
K07936                      KO                                     

Name
RAN
Definition
GTP-binding nuclear protein Ran
Pathway
ko03008  Ribosome biogenesis in eukaryotes
ko03013  RNA transport
ko05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    K07936  RAN; GTP-binding nuclear protein Ran
   03008 Ribosome biogenesis in eukaryotes
    K07936  RAN; GTP-binding nuclear protein Ran
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K07936  RAN; GTP-binding nuclear protein Ran
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03009 Ribosome biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03016 Transfer RNA biogenesis
    K07936  RAN; GTP-binding nuclear protein Ran
   03036 Chromosome and associated proteins
    K07936  RAN; GTP-binding nuclear protein Ran
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07936  RAN; GTP-binding nuclear protein Ran
   04031 GTP-binding proteins
    K07936  RAN; GTP-binding nuclear protein Ran
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     K07936  RAN; GTP-binding nuclear protein Ran
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-40S particles
   Export and cytoplasmic maturation factors
    K07936  RAN; GTP-binding nuclear protein Ran
  Pre-60S particles
   Export and cytoplasmic maturation factors
    K07936  RAN; GTP-binding nuclear protein Ran
Transfer RNA biogenesis [BR:ko03016]
 Eukaryotic type
  tRNA transport factors
   tRNA export factors
    K07936  RAN; GTP-binding nuclear protein Ran
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation and ciliogenesis proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     K07936  RAN; GTP-binding nuclear protein Ran
   Spindle formation proteins
    K07936  RAN; GTP-binding nuclear protein Ran
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07936  RAN; GTP-binding nuclear protein Ran
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ran Family
   Ran
    K07936  RAN; GTP-binding nuclear protein Ran
Genes
HSA: 5901(RAN)
PTR: 452414(RAN)
PPS: 100976346(RAN)
GGO: 101143548(RAN)
PON: 100173539(RAN) 100937596
NLE: 100581875(RAN) 100590022 100592573 100599771
MCC: 709200(RAN)
MCF: 102133660(RAN) 102134069
CSAB: 103218749 103239407(RAN)
RRO: 104655552(RAN) 104674363
RBB: 108526883(RAN)
CJC: 100400787(RAN)
SBQ: 101043259(RAN) 101046456
MMU: 19384(Ran) 19428(Rasl2-9) 75471(1700009N14Rik)
RNO: 313163(RGD1306195) 751812(Rasl2-9) 84509(Ran)
NGI: 103750614(Ran)
HGL: 101711994(Ran)
CCAN: 109695688(Ran)
OCU: 100352306(RAN) 100357230
TUP: 102500543(RAN)
CFA: 100499482(RAN) 100686305
VVP: 112920146 112933832(RAN)
AML: 100468957(RAN)
UMR: 103661236(RAN)
UAH: 113266861(RAN)
FCA: 101080666(RAN)
PTG: 102954016(RAN)
PPAD: 109257606(RAN)
AJU: 106986939(RAN)
BIU: 109562689 109571399(RAN)
BBUB: 102397525 102415657(RAN)
SSC: 397655(RAN)
BACU: 103016841(RAN)
LVE: 103070167 103082587(RAN)
OOR: 101281487 101283104(RAN)
PCAD: 102985469(RAN)
ECB: 100062767(RAN)
EPZ: 103560560(RAN)
EAI: 106841835(RAN)
MYB: 102239412(RAN)
MYD: 102754269(RAN)
MNA: 107529640(RAN)
DRO: 112308882 112310778(RAN)
PALE: 102893000(RAN)
RAY: 107502514 107511541(RAN)
MJV: 108388641(RAN) 108392341
LAV: 100655400(RAN) 100669230
TMU: 101345055
MDO: 100020008(RAN)
SHR: 100913923(RAN) 100916523
PCW: 110220348(RAN)
OAA: 100090125(RAN)
GGA: 396193(RAN)
MGP: 104913530(RAN)
CJO: 107321272(RAN)
NMEL: 110406273(RAN)
APLA: 101794739(RAN)
ACYG: 106031204(RAN)
TGU: 100190162(RAN)
LSR: 110477846(RAN)
SCAN: 103818200(RAN)
GFR: 102040216(RAN)
FAB: 101809752(RAN)
PHI: 102104465(RAN)
PMAJ: 107211879(RAN)
CCAE: 111936334(RAN)
CCW: 104688747(RAN)
ETL: 114061033(RAN)
FPG: 101918787(RAN)
FCH: 102059089(RAN)
CLV: 102091968(RAN)
EGZ: 104127186(RAN)
NNI: 104019840(RAN)
ACUN: 113486002(RAN)
PADL: 103914331(RAN)
AAM: 106489909(RAN)
ASN: 102370450(RAN)
AMJ: 102562653(RAN)
PSS: 102446816 102448079(RAN)
CMY: 102931665(RAN)
CPIC: 101952069(RAN)
ACS: 100561269(ran)
PVT: 110076603(RAN)
PBI: 103056862(RAN)
PMUR: 107295820(RAN)
TSR: 106549752(RAN)
PMUA: 114586337(RAN)
GJA: 107116017(RAN)
XLA: 100189578(ran.L) 108716335 379874(ran.S)
XTR: 448091(ran)
NPR: 108795534(RAN)
DRE: 30572(ran)
SANH: 107661941(ran) 107682846
IPU: 100528155(ran)
PHYP: 113542941(ran)
AMEX: 103033763(ran)
EEE: 113570736(ran)
TRU: 101070070(ran)
LCO: 104937671(ran)
NCC: 104953376(ran)
MZE: 101467159(ran)
ONL: 100707444(ran)
OLA: 101156259(ran)
XMA: 102234897(ran)
XCO: 114138775(ran)
PRET: 103471374(ran)
CVG: 107085660(ran)
NFU: 107376735(ran)
KMR: 108243060(ran)
ALIM: 106516424(ran)
AOCE: 111576486(ran)
CSEM: 103390946(ran)
POV: 109628339(ran)
LCF: 108878285(ran)
SDU: 111232462(ran)
SLAL: 111651316 111662736(ran)
HCQ: 109524377(ran)
MALB: 109953755(ran)
SASA: 100136389(RAN) 100136528(ran1) 100196560(ran) 106609900(RAN)
ELS: 105022884 105028585(ran)
LCM: 102364067(RAN)
CMK: 103188021(ran)
RTP: 109923190(ran)
CIN: 100181477
SPU: 581649
APLC: 110980697
SKO: 100374136
DSI: Dsimw501_GD12564(Dsim_GD12564) Dsimw501_GD22834(Dsim_GD22834) Dsimw501_GD24539(Dsim_GD24539)
DYA: Dyak_GE15102 Dyak_GE17316(Dyak_ran)
MDE: 101897713
LCQ: 111685136
AAG: 5571763
AME: 410280
BIM: 100747095
BTER: 100646748
CCAL: 108624891
OBB: 114875989
SOC: 105203546
MPHA: 105838998
AEC: 105147439
ACEP: 105622619
PBAR: 105426228
VEM: 105565440
HST: 105183188
DQU: 106747529
CFO: 105247973
LHU: 105673799
PGC: 109855901
OBO: 105279171
PCF: 106789205
NVI: 100114116
CSOL: 105365474
MDL: 103569822
TCA: 657695
DPA: 109535166
NVL: 108557121
BMOR: 692970
PMAC: 106720185
PRAP: 110999455
HAW: 110372579
TNL: 113491707
API: 100162905(Ran)
DNX: 107163659
AGS: 114132507
RMD: 113554622
CLEC: 106672259
ZNE: 110833573
TUT: 107368508
PTEP: 107439373
CEL: CELE_K01G5.4(ran-1)
CBR: CBG18317(Cbr-ran-1)
BMY: Bm1_44725
TSP: Tsp_04091
PCAN: 112561744
CRG: 105327885
OBI: 106877227
LAK: 106160330
SHX: MS3_08533
EGL: EGR_04178
NVE: 5508877
EPA: 110252234
ADF: 107334559
AMIL: 114960208
PDAM: 113681045
SPIS: 111330112
HMG: 100211661
ATH: AT5G20010(RAN-1) AT5G20020(RAN2) AT5G55080(RAN4) AT5G55190(RAN3)
TCC: 18588700
LJA: Lj0g3v0196629.1(Lj0g3v0196629.1) Lj0g3v0337519.1(Lj0g3v0337519.1) Lj1g3v1912870.1(Lj1g3v1912870.1) Lj4g3v1833610.1(Lj4g3v1833610.1)
RCU: 8278571
SLY: 778289(RAN1) 778290(RAN2A) 778291(RAN2B)
NTA: 107765348(Ran-B2) 107779563(Ran-B1) 107787005(Ran-A2) 107829920(Ran-A1)
DOSA: Os01t0611100-01(Os01g0611100) Os05t0574500-01(Os05g0574500) Os06t0600301-00(Os06g0600301)
OBR: 102709464
ATS: 109735455 109759745(LOC109759745) 109759796(LOC109759796)
PEQ: 110027225
CRE: CHLREDRAFT_128522(RAN1)
APRO: F751_5979
SCE: YLR293C(GSP1) YOR185C(GSP2)
ERC: Ecym_3097
KMX: KLMA_10225(GSP1) KLMA_50134(GSP1)
NCS: NCAS_0F00440(NCAS0F00440)
NDI: NDAI_0D02670(NDAI0D02670)
TPF: TPHA_0K01060(TPHA0K01060)
TBL: TBLA_0E00980(TBLA0E00980)
TDL: TDEL_0G03810(TDEL0G03810)
KAF: KAFR_0A04800(KAFR0A04800)
CAL: CAALFM_C206310CA(GSP1)
SLB: AWJ20_1622(GSP2)
NCR: NCU09269(ran)
NTE: NEUTE1DRAFT119293(NEUTE1DRAFT_119293)
MGR: MGG_09952
SSCK: SPSK_05396
TRE: TRIREDRAFT_75547(ran1)
MAW: MAC_05258
MAJ: MAA_03972
CMT: CCM_06188
ANI: AN5482.2
ANG: ANI_1_1342074(An08g10060)
ABE: ARB_07546
TVE: TRV_07436
PTE: PTT_04918
SPO: SPBC1289.03c(spi1)
CNE: CNE02890
CNB: CNBE2910
TASA: A1Q1_00836
ABP: AGABI1DRAFT111135(AGABI1DRAFT_111135)
ABV: AGABI2DRAFT190352(AGABI2DRAFT_190352)
WSE: WALSEDRAFT_62044(Gsp1p)
MGL: MGL_2972
MRT: MRET_3576
DDI: DDB_G0291235(ranA)
DFA: DFA_02199(ranA)
EHI: EHI_148190(1.t00138)
PCB: PCHAS_091400(PC000801.01.0)
TAN: TA06865
TPV: TP01_0757
BBO: BBOV_IV010920(23.m06098)
CPV: cgd7_220
SMIN: v1.2.019954.t1(symbB.v1.2.019954.t1) v1.2.029132.t1(symbB.v1.2.029132.t1)
 » show all
Reference
  Authors
Dasso M
  Title
The Ran GTPase: theme and variations.
  Journal
Curr Biol 12:R502-8 (2002)
DOI:10.1016/S0960-9822(02)00970-3
Reference
PMID:8692944
  Authors
Moroianu J, Blobel G, Radu A
  Title
Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta.
  Journal
Proc Natl Acad Sci U S A 93:7059-62 (1996)
DOI:10.1073/pnas.93.14.7059
  Sequence
[hsa:5901]
Reference
PMID:2108320
  Authors
Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P
  Title
Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.
  Journal
Mol Cell Biol 10:1793-8 (1990)
DOI:10.1128/MCB.10.4.1793
  Sequence
[hsa:5901]

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