KEGG   ORTHOLOGY: K07981
Entry
K07981                      KO                                     

Name
KIR2DL1_2_3, CD158A_B
Definition
killer cell immunoglobulin-like receptor 2DL1/2/3
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
   04612 Antigen processing and presentation
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K07981  KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
CD molecules [BR:ko04090]
 Proteins
  K07981  CD158a, KIR2DL1; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  K07981  CD158b1, KIR2DL2; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
  K07981  CD158b2, KIR2DL3; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
Genes
HSA: 3802(KIR2DL1) 3803(KIR2DL2) 3804(KIR2DL3)
PTR: 750609(KIR2DL3)
GGO: 115933447
PON: 100437371
CSAB: 103235276
Reference
PMID:7716543
  Authors
Colonna M, Samaridis J
  Title
Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.
  Journal
Science 268:405-8 (1995)
DOI:10.1126/science.7716543
  Sequence
[hsa:3802 3804]
Reference
  Authors
Campbell KS, Purdy AK
  Title
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations.
  Journal
Immunology 132:315-25 (2011)
DOI:10.1111/j.1365-2567.2010.03398.x

KEGG   ORTHOLOGY: K24232
Entry
K24232                      KO                                     

Name
KIR2DL5, CD158F
Definition
killer cell immunoglobulin-like receptor 2DL5
Pathway
ko04612  Antigen processing and presentation
ko04650  Natural killer cell mediated cytotoxicity
ko05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
   04612 Antigen processing and presentation
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
 09160 Human Diseases
  09163 Immune disease
   05332 Graft-versus-host disease
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K24232  KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
CD molecules [BR:ko04090]
 Proteins
  K24232  CD158f1, KIR2DL5; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5
Genes
HSA: 57292(KIR2DL5A)
PTR: 107969810
PPS: 100986982
GGO: 115933442
PON: 100936503
BTA: 282860(KIR2DL5A)
BOM: 102280334
BBUB: 102402612
Reference
  Authors
Vilches C, Rajalingam R, Uhrberg M, Gardiner CM, Young NT, Parham P
  Title
KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.
  Journal
J Immunol 164:5797-804 (2000)
DOI:10.4049/jimmunol.164.11.5797
  Sequence
[hsa:57292]

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