KEGG   ORTHOLOGY: K08009
Entry
K08009                      KO                                     

Name
CYBA, P22PHOX
Definition
cytochrome b-245, alpha polypeptide
Pathway
ko04145  Phagosome
ko04380  Osteoclast differentiation
ko04621  NOD-like receptor signaling pathway
ko04670  Leukocyte transendothelial migration
ko05020  Prion disease
ko05140  Leishmaniasis
ko05418  Fluid shear stress and atherosclerosis
Disease
H00098  Chronic granulomatous disease
H01167  Gluconobacter infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
   04670 Leukocyte transendothelial migration
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
Membrane trafficking [BR:ko04131]
 Others
  NADPH oxidases (Nox) and associated proteins
   Nox associated proteins
    K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
Other DBs
TC: 5.B.1.1.1
Genes
HSA: 1535(CYBA)
PTR: 468068(CYBA)
PPS: 100986914
GGO: 101141497
PON: 100456737
NLE: 100595279
MCC: 696748
MCF: 102143777
CSAB: 103233451
RRO: 104655986
RBB: 108520444
CJC: 100414967(CYBA)
SBQ: 101045425
MMU: 13057(Cyba)
MCAL: 110300473
MPAH: 110337603
RNO: 79129(Cyba)
MUN: 110545249
CGE: 100766833
NGI: 103740013
HGL: 101717043
CCAN: 109692739
OCU: 100008800(CYBA)
TUP: 102471991
CFA: 489664(CYBA)
VVP: 112924621
AML: 100482979
UMR: 103673846
UAH: 113252151
ORO: 101364731
ELK: 111152928
FCA: 101091745
PPAD: 109245544
AJU: 113604395
BTA: 281111(CYBA)
BOM: 102270937
BIU: 109572735
BBUB: 102413072
CHX: 102188617
OAS: 101106452
SSC: 397507(CYBA)
CFR: 102509853
CDK: 105104683
BACU: 102999052
LVE: 103090543
OOR: 101274948
DLE: 111179403
PCAD: 102973615
ECB: 100049843(CYBA)
EAI: 106828257
MYB: 102242122
MYD: 102760442
MNA: 107525738
HAI: 109389148
DRO: 112300849
PALE: 102885155
RAY: 107502360
MJV: 108385610
LAV: 100666572
TMU: 101355438
MDO: 100026086
SHR: 100932491
PCW: 110210311
OAA: 100084242
GGA: 100859840(CYBA)
MGP: 100544408
CJO: 107319525
NMEL: 110404326
TGU: 100230391
LSR: 110468832
SCAN: 103816882
GFR: 102036039
FAB: 101819099
PHI: 102100453
PMAJ: 107210059
CCAE: 111934735
ETL: 114060625
FPG: 101915504
CLV: 102091746
NNI: 104023645
AAM: 106491416
ASN: 102385608
AMJ: 102558462
PSS: 102449370
CMY: 102946998
CPIC: 101937351
ACS: 100555174
PVT: 110076319
PBI: 103052761
PMUR: 107283532
TSR: 106549747
PMUA: 114602128
GJA: 107119316
XLA: 108704084(cyba.S) 446853(cyba.L)
XTR: 549234(cyba)
NPR: 108802186
DRE: 393551(cyba)
IPU: 108264585
PHYP: 113526918
AMEX: 103041742
EEE: 113570890
TRU: 445889(p22phox)
LCO: 104927415
NCC: 104964892
MZE: 101470167
ONL: 100705310
OLA: 101170577
XMA: 102219145
XCO: 114142753
PRET: 103462573
CVG: 107084165
NFU: 107381322
KMR: 108250930
ALIM: 106513204
AOCE: 111577161
CSEM: 103379180
POV: 109636777
LCF: 108877826
SDU: 111222344
SLAL: 111646239
HCQ: 109525911
BPEC: 110175258
MALB: 109965069
ELS: 105015958
SFM: 108940834
PKI: 111861200
LCM: 102353925
CMK: 103175997
RTP: 109937056
BFO: 118417857
CIN: 100182370
SPU: 100889590
APLC: 110975693
SKO: 102806390
PTEP: 107455428
PCAN: 112576562
MYI: 110449899
OBI: 106870690
LAK: 106157842
NVE: 5508056
EPA: 110245830
ADF: 107348189
AMIL: 114954170
PDAM: 113675015
SPIS: 111340161
DGT: 114517092
HMG: 100213059
AQU: 100637130
DDI: DDB_G0267460(cybA)
DFA: DFA_07591(cybA)
 » show all
Reference
  Authors
Miyano K, Sumimoto H
  Title
Role of the small GTPase Rac in p22phox-dependent NADPH oxidases.
  Journal
Biochimie 89:1133-44 (2007)
DOI:10.1016/j.biochi.2007.05.003
Reference
PMID:3368442
  Authors
Parkos CA, Dinauer MC, Walker LE, Allen RA, Jesaitis AJ, Orkin SH
  Title
Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.
  Journal
Proc Natl Acad Sci U S A 85:3319-23 (1988)
DOI:10.1073/pnas.85.10.3319
  Sequence
[hsa:1535]

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