KEGG   ORTHOLOGY: K08198
Entry
K08198                      KO                                     

Name
SLC22A1, OCT1
Definition
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Pathway
ko04976  Bile secretion
ko05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
 Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08198  SLC22A1, OCT1; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1
Other DBs
GO: 0015101
TC: 2.A.1.19.1
Genes
HSA: 6580(SLC22A1)
PTR: 472177(SLC22A1)
PPS: 100993403(SLC22A1)
GGO: 101147842(SLC22A1)
PON: 100436901(SLC22A1)
NLE: 100587868(SLC22A1)
MCC: 703449(SLC22A1)
MCF: 102116123(SLC22A1)
CSAB: 103240834(SLC22A1)
RRO: 104666418(SLC22A1)
RBB: 108516182(SLC22A1)
CJC: 100412933(SLC22A1)
SBQ: 101027460(SLC22A1)
MMU: 20517(Slc22a1)
MCAL: 110283911(Slc22a1)
MPAH: 110338308(Slc22a1)
RNO: 24904(Slc22a1)
MUN: 110554860
CGE: 100763203(Slc22a1)
NGI: 103734803(Slc22a1)
HGL: 101706844(Slc22a1)
CCAN: 109682989(Slc22a1)
OCU: 100008659(SLC22A1)
CFA: 484068(SLC22A1)
VVP: 112935152
AML: 100476497(SLC22A1)
UMR: 103660829(SLC22A1)
UAH: 113259624
ORO: 101381071(SLC22A1)
ELK: 111158719
FCA: 101094761(SLC22A1)
PTG: 102952142(SLC22A1)
PPAD: 109245396(SLC22A1)
AJU: 106989429
BTA: 519461(SLC22A1)
BOM: 102278342(SLC22A1)
BIU: 109564097
BBUB: 102403206
CHX: 102183874(SLC22A1)
OAS: 101112740(SLC22A1)
SSC: 397049(SLC22A1)
CFR: 102510283(SLC22A1)
CDK: 105100382(SLC22A1)
BACU: 103008472(SLC22A1)
LVE: 103076375(SLC22A1)
OOR: 101278500(SLC22A1)
DLE: 111167637(SLC22A1)
PCAD: 102980252
ECB: 100058455(SLC22A1)
EPZ: 103558447(SLC22A1)
EAI: 106842042(SLC22A1)
HAI: 109394003(SLC22A1)
PALE: 102887758
RAY: 107514734(SLC22A1)
MJV: 108409364(SLC22A1)
LAV: 100656903(SLC22A1)
TMU: 101343732
MDO: 100027984(SLC22A1)
SHR: 100927176
PCW: 110208613
AME: 412056
BIM: 100742475
BTER: 100648294
OBB: 114878459
AEC: 105153921
PBAR: 105424832
DQU: 106744070
LHU: 105672804
PGC: 109851901
PCF: 106784243
NVI: 100119124
CSOL: 105367618
MDL: 103570983
ATD: 109596990
NVL: 108559750
BMAN: 114248734
PRAP: 110995226
TNL: 113505949
ZNE: 110840488
 » show all
Reference
PMID:9187257
  Authors
Zhang L, Dresser MJ, Gray AT, Yost SC, Terashita S, Giacomini KM
  Title
Cloning and functional expression of a human liver organic cation transporter.
  Journal
Mol Pharmacol 51:913-21 (1997)
DOI:10.1124/mol.51.6.913
  Sequence
[hsa:6580]
Reference
  Authors
Klaassen CD, Aleksunes LM
  Title
Xenobiotic, bile acid, and cholesterol transporters: function and regulation.
  Journal
Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014

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