KEGG   ORTHOLOGY: K08242
Entry
K08242                      KO                                     

Name
E2.1.1.143
Definition
24-methylenesterol C-methyltransferase [EC:2.1.1.143]
Pathway
ko00100  Steroid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K08242  E2.1.1.143; 24-methylenesterol C-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.143  24-methylenesterol C-methyltransferase
     K08242  E2.1.1.143; 24-methylenesterol C-methyltransferase
Other DBs
RN: R05776
GO: 0030797
Genes
ATH: AT1G20330(SMT2) AT1G76090(SMT3)
ALY: 9325120 9329159
CRB: 17894477 17897656
CSAT: 104702364 104713272 104740730 104751502 104751503 104756386 104776150
EUS: EUTSA_v10008036mg EUTSA_v10018759mg
BRP: 103832055 108870355 117125925
BNA: 106347090 106347091 106349985 106406523 106421679 106432484 106433699 106433723
BOE: 106294968 106294969 106301097 106321642
RSZ: 108811804 108812221 108840045
THJ: 104809656 104811446 104813772
CPAP: 110818251
CIT: 102622046
TCC: 18591627
EGR: 104448882
GMX: 100791154(SMT2-2) 100804517(SMT2-1)
CCAJ: 109802073
CAM: 101496973
LJA: Lj1g3v2254700.1(Lj1g3v2254700.1) Lj1g3v2254710.1(Lj1g3v2254710.1) Lj1g3v2254710.2(Lj1g3v2254710.2) Lj1g3v2254710.3(Lj1g3v2254710.3)
ADU: 107460153
AIP: 107609799
FVE: 101296451
PPER: 18788663
PMUM: 103321192
PAVI: 110768162
PXB: 103927358
CSV: 101220177
CMO: 103503852
MCHA: 111010418
CMAX: 111476770
CMOS: 111443718
CPEP: 111797180
RCU: 8267837
QSU: 112004464
INI: 109162135
SOE: 110776014
NNU: 104603677
OSA: 4331540
DOSA: Os03t0136200-01(Os03g0136200)
OBR: 102714159
ATS: 109735428(LOC109735428) 109766957(LOC109766957)
SBI: 8057407
ZMA: 100192647(smt2) 100282753
SITA: 101761370
PEQ: 110021793
AOF: 109838936
ATR: 18424175
SMO: SELMODRAFT_152839(SMT2-2) SELMODRAFT_449634(SMT2-1)
CRE: CHLREDRAFT_161904(SMT1)
APRO: F751_0617
 » show all
Reference
PMID:9746350
  Authors
Bouvier-Nave P, Husselstein T, Benveniste P
  Title
Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis.
  Journal
Eur J Biochem 256:88-96 (1998)
DOI:10.1046/j.1432-1327.1998.2560088.x
  Sequence
[osa:4331540]

KEGG   ENZYME: 2.1.1.143
Entry
EC 2.1.1.143                Enzyme                                 

Name
24-methylenesterol C-methyltransferase;
SMT2;
24-methylenelophenol C-241-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 24-methylenelophenol = S-adenosyl-L-homocysteine + (Z)-24-ethylidenelophenol [RN:R05776]
Reaction(KEGG)
R05776
Substrate
S-adenosyl-L-methionine [CPD:C00019];
24-methylenelophenol [CPD:C11522]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
(Z)-24-ethylidenelophenol [CPD:C11523]
Comment
This is the second methylation step of plant sterol biosynthesis (cf EC 2.1.1.142, cycloartenol 24-C-methyltransferase).
History
EC 2.1.1.143 created 2001
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K08242  24-methylenesterol C-methyltransferase
Genes
ATH: AT1G20330(SMT2) AT1G76090(SMT3)
ALY: 9325120 9329159
CRB: 17894477 17897656
CSAT: 104702364 104713272 104740730 104751502 104751503 104756386 104776150
EUS: EUTSA_v10008036mg EUTSA_v10018759mg
BRP: 103832055 108870355 117125925
BNA: 106347090 106347091 106349985 106406523 106421679 106432484 106433699 106433723
BOE: 106294968 106294969 106301097 106321642
RSZ: 108811804 108812221 108840045
THJ: 104809656 104811446 104813772
CPAP: 110818251
CIT: 102622046
TCC: 18591627
EGR: 104448882
GMX: 100791154(SMT2-2) 100804517(SMT2-1)
CCAJ: 109802073
CAM: 101496973
LJA: Lj1g3v2254700.1(Lj1g3v2254700.1) Lj1g3v2254710.1(Lj1g3v2254710.1) Lj1g3v2254710.2(Lj1g3v2254710.2) Lj1g3v2254710.3(Lj1g3v2254710.3)
ADU: 107460153
AIP: 107609799
FVE: 101296451
PPER: 18788663
PMUM: 103321192
PAVI: 110768162
PXB: 103927358
CSV: 101220177
CMO: 103503852
MCHA: 111010418
CMAX: 111476770
CMOS: 111443718
CPEP: 111797180
RCU: 8267837
QSU: 112004464
INI: 109162135
SOE: 110776014
NNU: 104603677
OSA: 4331540
DOSA: Os03t0136200-01(Os03g0136200)
OBR: 102714159
ATS: 109735428(LOC109735428) 109766957(LOC109766957)
SBI: 8057407
ZMA: 100192647(smt2) 100282753
SITA: 101761370
PEQ: 110021793
AOF: 109838936
ATR: 18424175
SMO: SELMODRAFT_152839(SMT2-2) SELMODRAFT_449634(SMT2-1)
CRE: CHLREDRAFT_161904(SMT1)
APRO: F751_0617
 » show all
Reference
1  [PMID:9746350]
  Authors
Bouvier-Nave P, Husselstein T, Benveniste P.
  Title
Two families of sterol methyltransferases are involved in the first and the second methylation steps of plant sterol biosynthesis.
  Journal
Eur J Biochem 256:88-96 (1998)
DOI:10.1046/j.1432-1327.1998.2560088.x
  Sequence
[osa:4331540]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.143
IUBMB Enzyme Nomenclature: 2.1.1.143
ExPASy - ENZYME nomenclature database: 2.1.1.143
BRENDA, the Enzyme Database: 2.1.1.143
CAS: 67165-89-3

KEGG   REACTION: R05776
Entry
R05776                      Reaction                               

Name
S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase
Definition
S-Adenosyl-L-methionine + 24-Methylenelophenol <=> S-Adenosyl-L-homocysteine + 24-Ethylidenelophenol
Equation
Reaction class
RC00003  C00019_C00021
RC01470  C11522_C11523
Enzyme
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Orthology
K08242  24-methylenesterol C-methyltransferase [EC:2.1.1.143]
Other DBs
RHEA: 21047

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