KEGG   ORTHOLOGY: K08605
Entry
K08605                      KO                                     

Name
gelE
Definition
coccolysin [EC:3.4.24.30]
Pathway
ko02024  Quorum sensing
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K08605  gelE; coccolysin
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08605  gelE; coccolysin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.30  coccolysin
     K08605  gelE; coccolysin
Peptidases and inhibitors [BR:ko01002]
 Metallo peptidases
  Family M4: thermolysin family
   K08605  gelE; coccolysin
Other DBs
COG: COG3227
Genes
EFA: EF1818
EFL: EF62_2189(gelE)
EFI: OG1RF_11526(gelE)
EFD: EFD32_1547(gelE)
EFN: DENG_02000
EFQ: DR75_810(gelE)
ENE: ENT_12320
Reference
  Authors
Waters CM, Antiporta MH, Murray BE, Dunny GM
  Title
Role of the Enterococcus faecalis GelE protease in determination of cellular chain length, supernatant pheromone levels, and degradation of fibrin and misfolded surface proteins.
  Journal
J Bacteriol 185:3613-23 (2003)
DOI:10.1128/JB.185.12.3613-3623.2003
  Sequence
[efa:EF1818]
Reference
  Authors
Park SY, Shin YP, Kim CH, Park HJ, Seong YS, Kim BS, Seo SJ, Lee IH
  Title
Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b.
  Journal
J Immunol 181:6328-36 (2008)
DOI:10.4049/jimmunol.181.9.6328

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