KEGG   ORTHOLOGY: K08692Help
Entry
K08692                      KO                                     

Name
mtkB
Definition
malate-CoA ligase subunit alpha [EC:6.2.1.9]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00346  Formaldehyde assimilation, serine pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K08692  mtkB; malate-CoA ligase subunit alpha
  09102 Energy metabolism
   00680 Methane metabolism
    K08692  mtkB; malate-CoA ligase subunit alpha
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.9  malate---CoA ligase
     K08692  mtkB; malate-CoA ligase subunit alpha
BRITE hierarchy
Other DBs
RN: R01256
GO: 0050074
Genes
MCA: MCA1741(sucD-2)
MMT: Metme_2693
MDN: JT25_000145
MDH: AYM39_08400
MKO: MKLM6_1754
METL: U737_10270(sucD)
MAH: MEALZ_3215(mtkB)
MPSY: CEK71_18045
TSN: W908_06420
BPH: Bphy_5926
MPT: Mpe_A3256
NEU: NE1811
NET: Neut_0605
METR: BSY238_255(sucD)
MLO: mlr1326
AMIH: CO731_05427(sucD_2)
SFH: SFHH103_02476(sucd1)
SFD: USDA257_c22010(mtkB)
SAME: SAMCFNEI73_pC0658(mtkB)
MEX: Mext_1800
MEA: Mex_1p1731(mtkB)
MDI: METDI2483(mtkB)
MCH: Mchl_2136
MPO: Mpop_1752
MET: M446_6557
MNO: Mnod_7117
MOR: MOC_4188
META: Y590_08605
MAQU: Maq22A_c19260(mtkB)
MSL: Msil_1717
HDN: Hden_3151
HMC: HYPMC_4393(mtkB)
FIL: BN1229_v1_1242(sucD)
FIY: BN1229_v1_1240(sucD)
MSC: BN69_1173
MROS: EHO51_12195(sucD)
PLEO: OHA_1_00679(sucD_1)
MCG: GL4_3373
HDI: HDIA_2219(sucD_2)
SIL: SPO1569
RDE: RD1_4246(mtkB)
RLI: RLO149_c036810(mtkB)
PAMN: pAMV1p0131(mtkA)
DSH: Dshi_2492(sucD2)
LEJ: ETW24_17890(sucD)
CID: P73_3960
RMM: ROSMUCSMR3_03453(sucD)
TAW: EI545_00090(sucD)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7961516
  Authors
Chistoserdova LV, Lidstrom ME
  Title
Genetics of the serine cycle in Methylobacterium extorquens AM1: identification, sequence, and mutation of three new genes involved in C1 assimilation, orf4, mtkA, and mtkB.
  Journal
J Bacteriol 176:7398-404 (1994)
DOI:10.1128/JB.176.23.7398-7404.1994
  Sequence

KEGG   ORTHOLOGY: K14067Help
Entry
K14067                      KO                                     

Name
mtkA
Definition
malate-CoA ligase subunit beta [EC:6.2.1.9]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00346  Formaldehyde assimilation, serine pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K14067  mtkA; malate-CoA ligase subunit beta
  09102 Energy metabolism
   00680 Methane metabolism
    K14067  mtkA; malate-CoA ligase subunit beta
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.9  malate---CoA ligase
     K14067  mtkA; malate-CoA ligase subunit beta
BRITE hierarchy
Other DBs
RN: R01256
GO: 0050074
Genes
PHD: 102320684
MCA: MCA1740(sucC-2)
MMT: Metme_2694
MDN: JT25_000150(sucC)
MDH: AYM39_08395(sucC)
MKO: MKLM6_1753
METL: U737_10265
MAH: MEALZ_3216(mtkA)
MPSY: CEK71_18040
MMAI: sS8_2224
TSN: W908_06425(sucC)
BPH: Bphy_5927
MPT: Mpe_A3257
NEU: NE1810
NET: Neut_0606
NCO: AAW31_08290(sucC)
NUR: ATY38_03750(sucC)
METR: BSY238_256(sucC)
MLO: mlr1324
MAMO: A6B35_22115(sucC)
AMIH: CO731_05426(sucC_2)
SFH: SFHH103_02475(succ1)
SFD: USDA257_c22020(mtkA)
SAME: SAMCFNEI73_pC0657(mtkA)
MEX: Mext_1799
MEA: Mex_1p1730(mtkA)
MDI: METDI2482(mtkA)
MCH: Mchl_2135
MPO: Mpop_1751
MET: M446_6556
MNO: Mnod_7116
MOR: MOC_4189
META: Y590_08600(sucC)
MAQU: Maq22A_c19265(mtkA)
MSL: Msil_1716
MTUN: MTUNDRAET4_3406(mtkA)
HDN: Hden_3152
HMC: HYPMC_4394(mtkA)
HNI: W911_15810(sucC)
FIL: BN1229_v1_1241(sucC)
FIY: BN1229_v1_1239(sucC)
MSC: BN69_1174(sucC1)
PLEO: OHA_1_00680(sucC_1)
MCG: GL4_3374
HDI: HDIA_2218(sucC_1)
SIL: SPO1568
RDE: RD1_1162(mtkA)
RLI: RLO149_c036820(mtkA)
PAMN: pAMV1p0132(mtkB)
DSH: Dshi_2491(sucC2)
LMD: METH_18375(sucC)
CID: P73_3959
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7961516
  Authors
Chistoserdova LV, Lidstrom ME
  Title
Genetics of the serine cycle in Methylobacterium extorquens AM1: identification, sequence, and mutation of three new genes involved in C1 assimilation, orf4, mtkA, and mtkB.
  Journal
J Bacteriol 176:7398-404 (1994)
DOI:10.1128/JB.176.23.7398-7404.1994
  Sequence

KEGG   ORTHOLOGY: K14471Help
Entry
K14471                      KO                                     

Name
smtA1
Definition
succinyl-CoA:(S)-malate CoA-transferase subunit A [EC:2.8.3.22]
Pathway
ko00660  C5-Branched dibasic acid metabolism
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    K14471  smtA1; succinyl-CoA:(S)-malate CoA-transferase subunit A
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14471  smtA1; succinyl-CoA:(S)-malate CoA-transferase subunit A
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.3  CoA-transferases
    2.8.3.22  succinyl-CoA---L-malate CoA-transferase
     K14471  smtA1; succinyl-CoA:(S)-malate CoA-transferase subunit A
BRITE hierarchy
Other DBs
RN: R00406 R03154
COG: COG1804
Genes
APP: CAP2UW1_2505
RRS: RoseRS_4176
RCA: Rcas_0909
CAU: Caur_0179
CHL: Chy400_0191
CAG: Cagg_1331
AG: ABF14399(smtA)
TaxonomyKoalaUniProt
Reference
  Authors
Friedmann S, Steindorf A, Alber BE, Fuchs G
  Title
Properties of succinyl-coenzyme A:L-malate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.
  Journal
J Bacteriol 188:2646-55 (2006)
DOI:10.1128/JB.188.7.2646-2655.2006
  Sequence
Reference
  Authors
Zarzycki J, Brecht V, Muller M, Fuchs G
  Title
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
  Journal
Proc Natl Acad Sci U S A 106:21317-22 (2009)
DOI:10.1073/pnas.0908356106

KEGG   ORTHOLOGY: K14472Help
Entry
K14472                      KO                                     

Name
smtB
Definition
succinyl-CoA:(S)-malate CoA-transferase subunit B [EC:2.8.3.22]
Pathway
ko00660  C5-Branched dibasic acid metabolism
ko00720  Carbon fixation pathways in prokaryotes
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    K14472  smtB; succinyl-CoA:(S)-malate CoA-transferase subunit B
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14472  smtB; succinyl-CoA:(S)-malate CoA-transferase subunit B
Enzymes [BR:ko01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.3  CoA-transferases
    2.8.3.22  succinyl-CoA---L-malate CoA-transferase
     K14472  smtB; succinyl-CoA:(S)-malate CoA-transferase subunit B
BRITE hierarchy
Other DBs
RN: R00406 R03154
COG: COG1804
Genes
APP: CAP2UW1_2506
RRS: RoseRS_4175
RCA: Rcas_0910
CAU: Caur_0178
CHL: Chy400_0190
CAG: Cagg_1330
AG: ABF14400(smtB)
TaxonomyKoalaUniProt
Reference
  Authors
Friedmann S, Steindorf A, Alber BE, Fuchs G
  Title
Properties of succinyl-coenzyme A:L-malate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.
  Journal
J Bacteriol 188:2646-55 (2006)
DOI:10.1128/JB.188.7.2646-2655.2006
  Sequence
Reference
  Authors
Zarzycki J, Brecht V, Muller M, Fuchs G
  Title
Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.
  Journal
Proc Natl Acad Sci U S A 106:21317-22 (2009)
DOI:10.1073/pnas.0908356106

KEGG   REACTION: R01256Help
Entry
R01256                      Reaction                               

Name
(S)-malate:CoA ligase (ADP-forming)
Definition
ATP + (S)-Malate + CoA <=> ADP + Orthophosphate + L-Malyl-CoA
Equation
Comment
reversible
Reaction class
RC00002  C00002_C00008
RC00004  C00010_C04348
RC00014  C00149_C04348
Enzyme
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00346  Formaldehyde assimilation, serine pathway
Orthology
K08692  malate-CoA ligase subunit alpha [EC:6.2.1.9]
K14067  malate-CoA ligase subunit beta [EC:6.2.1.9]
Other DBs
RHEA: 26196

KEGG   REACTION: R00406Help
Entry
R00406                      Reaction                               

Name
succinyl-CoA:(S)-malate CoA-transferase
Definition
Succinyl-CoA + (S)-Malate <=> Succinate + L-Malyl-CoA
Equation
Reaction class
RC00014  C00042_C00091  C00149_C04348
Enzyme
Pathway
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00376  3-Hydroxypropionate bi-cycle
M00376  3-Hydroxypropionate bi-cycle
Orthology
K14471  succinyl-CoA:(S)-malate CoA-transferase subunit A [EC:2.8.3.22]
K14472  succinyl-CoA:(S)-malate CoA-transferase subunit B [EC:2.8.3.22]
Reference
1  [PMID:16547052]
  Authors
Friedmann S, Steindorf A, Alber BE, Fuchs G.
  Title
Properties of succinyl-coenzyme A:L-malate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.
  Journal
J Bacteriol 188:2646-55 (2006)
DOI:10.1128/JB.188.7.2646-2655.2006
Other DBs
RHEA: 38258

DBGET integrated database retrieval system