Entry |
|
Symbol |
EPHX2
|
Name |
|
Pathway |
map00625 | Chloroalkane and chloroalkene degradation |
map01120 | Microbial metabolism in diverse environments |
map05207 | Chemical carcinogenesis - receptor activation |
map05208 | Chemical carcinogenesis - reactive oxygen species |
|
Reaction |
R05842 | ethylene oxide hydrolase |
|
Disease |
H00155 | Familial hypercholesterolemia |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
09111 Xenobiotics biodegradation and metabolism
00625 Chloroalkane and chloroalkene degradation
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
05208 Chemical carcinogenesis - reactive oxygen species
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
01002 Peptidases and inhibitors
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
Enzymes [BR:ko01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.76 lipid-phosphate phosphatase
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
3.3 Acting on ether bonds
3.3.2 Ether hydrolases
3.3.2.10 soluble epoxide hydrolase
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
Protein phosphatases and associated proteins [BR:ko01009]
HAD phosphatases
Other HAD phosphatases
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
Peptidases and inhibitors [BR:ko01002]
Serine peptidases
Family S33
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Newman JW, Morisseau C, Harris TR, Hammock BD |
Title |
The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. |
Journal |
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Sequence |
|
Reference |
|
Authors |
Beetham JK, Tian T, Hammock BD |
Title |
cDNA cloning and expression of a soluble epoxide hydrolase from human liver. |
Journal |
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Sequence |
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