KEGG   ORTHOLOGY: K08732
Entry
K08732                      KO                                     
Symbol
RALGDS
Name
ral guanine nucleotide dissociation stimulator
Pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04072  Phospholipase D signaling pathway
map05200  Pathways in cancer
map05210  Colorectal cancer
map05212  Pancreatic cancer
map05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
   04015 Rap1 signaling pathway
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
   04072 Phospholipase D signaling pathway
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
   05231 Choline metabolism in cancer
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
  09162 Cancer: specific types
   05210 Colorectal cancer
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
   05212 Pancreatic cancer
    K08732  RALGDS; ral guanine nucleotide dissociation stimulator
Other DBs
GO: 0008321
Genes
HSA: 5900(RALGDS)
PTR: 458697(RGL4) 464824(RALGDS)
PPS: 100969771 100977720(RALGDS)
GGO: 101144743(RALGDS)
PON: 100434751 100451493(RALGDS)
NLE: 100579487 100589231(RALGDS) 115835869
HMH: 116475810(RALGDS)
MCC: 100426259 106992479 106995478 106995524 114670406 710293 710997 711158 713249 714436(RALGDS)
MCF: 102121408(RALGDS) 102124288 102125458
MTHB: 126929238 126929502 126929506 126929550 126929580 126929584 126929625 126929778 126929779 126929780 126936899 126947346 126964069
MNI: 105464075(RALGDS) 105464191 105464203 105480640 105497377 105497421 112422941
CSAB: 103223583 103239705(RALGDS)
CATY: 105575634 105575857 105594177(RALGDS) 105599414
PANU: 100997587 101006888(RALGDS)
TGE: 112607916(RALGDS) 112632401 112632635 112632636 112632868 112632869
MLEU: 105530438 105533469 105537592 105542946(RALGDS) 105546073(RGL4) 105552366
RRO: 104669737(RALGDS) 104674726
RBB: 108513486(RALGDS) 108528764
TFN: 117073836(RALGDS) 117087293
PTEH: 111524003(RALGDS) 111530411
CANG: 105504139(RALGDS) 105514932 105519370
CJC: 100409316(RALGDS)
SBQ: 101029174(RALGDS)
CIMI: 108295416(RALGDS)
CSYR: 103250925(RALGDS)
MMUR: 105859871(RALGDS)
LCAT: 123646555(RALGDS)
PCOQ: 105806629(RALGDS)
OGA: 100953476(RALGDS)
MMU: 19730(Ralgds)
MCAL: 110286147(Ralgds)
MPAH: 110317707(Ralgds)
RNO: 29622(Ralgds)
MCOC: 116089898(Ralgds)
ANU: 117703478(Ralgds)
MUN: 110549995(Ralgds)
CGE: 100771841(Ralgds)
MAUA: 101833106(Ralgds)
PROB: 127222676(Ralgds)
PLEU: 114702785(Ralgds)
MORG: 121462907(Ralgds)
MFOT: 126509280
AAMP: 119819393(Ralgds)
NGI: 103742830(Ralgds)
HGL: 101700047(Ralgds)
CPOC: 100722725(Ralgds)
CCAN: 109677013 109677869 109678448 109683009 109690895 109690997(Ralgds) 109699717 109701306 109701840
DORD: 105987223 105989429(Ralgds) 105993771
DSP: 122109018(Ralgds) 122114492 122114847 122120732 122120746 122120747 122120774 122120806 122120809 122120812 122120814 122120818 122120862 122120901 122120903 122120905 122124476
PLOP: 125344534 125344567 125344605 125350781(Ralgds) 125352435 125352446 125352469 125364257
NCAR: 124964488 124973713 124973758 124973773 124973926 124974333 124975572
OCU: 103345957 103345959 103346586 103346760
OPI: 101534158(RALGDS)
TUP: 102479691(RALGDS)
GVR: 103581819 103582164(RALGDS)
CFA: 100855428 480686(RALGDS) 611891
CLUD: 112662313 112674653 112677375(RALGDS) 118354211 118355030 118355031
VVP: 112928009(RALGDS)
VLG: 121473707(RALGDS)
NPO: 129513831(RALGDS)
AML: 100472281
UMR: 103670397(RALGDS)
UAH: 113247941 113249103 113249140 113250009 113266555(RALGDS)
UAR: 123775706(RALGDS) 123779677 123784908 123784911 123803286 123803339
ELK: 111145587
LLV: 125083157 125109844 125109847
MPUF: 101672726(RALGDS)
NVS: 122917134(RALGDS)
ORO: 101386629(RALGDS)
EJU: 114198818(RALGDS)
ZCA: 113934764(RALGDS) 113938139
MLX: 118018104(RALGDS)
NSU: 110581484(RALGDS)
LWW: 102737721(RALGDS)
FCA: 101090558(RALGDS) 102899245
PYU: 121035155(RALGDS)
PBG: 122474949(RALGDS) 122478439 122478535 122478537 122487681 122497556 122497557
LRUF: 124503890 124525632
PTG: 102965767(RALGDS)
PPAD: 109249977(RALGDS)
PUC: 125922835
AJU: 106985322 106989551 113597310
HHV: 120230137(RALGDS)
BTA: 513723(RALGDS)
BOM: 102284256(RALGDS)
BIU: 109565671(RALGDS) 109565672
BBUB: 102404125(RALGDS)
BBIS: 105000869(RALGDS)
CHX: 102187410(RALGDS)
OAS: 101118864(RALGDS)
BTAX: 128055089(RALGDS)
ODA: 120852130(RALGDS)
CCAD: 122442306(RALGDS)
SSC: 100513970(RALGDS)
CFR: 102503669(RALGDS)
CBAI: 105069723(RALGDS)
CDK: 105085184(RALGDS)
VPC: 102528835
BACU: 103008135(RALGDS)
LVE: 103086535(RALGDS)
OOR: 101280055(RALGDS)
DLE: 111177083(RALGDS)
PCAD: 102992808(RALGDS)
PSIU: 116755498(RALGDS)
NASI: 112411278(RALGDS)
ECB: 100052576 100054137 100056032 100063871 100069402(RALGDS) 102147367 102148588 102149317 102149416 102149785 102150685 106780978 106781089 106781151 106781162
EPZ: 103544618 103553681(RALGDS)
EAI: 106835340 106839449 106841638 106845364(RALGDS) 106848366 123275672 123283947 123285599 123286146 123286149 123286150
MYB: 102240340(RALGDS)
MYD: 102766224(RALGDS) 102771781
MMYO: 118660540 118666917(RALGDS)
MLF: 102418938
MNA: 107524673(RALGDS)
PKL: 118708879(RALGDS)
HAI: 109382359(RALGDS)
DRO: 112306313(RALGDS)
SHON: 118980105(RALGDS)
AJM: 119036094(RALGDS)
PDIC: 114504710(RALGDS)
PHAS: 123823464(RALGDS)
MMF: 118629545(RALGDS) 118630659
RFQ: 117032148(RALGDS)
PALE: 102880177(RALGDS)
PGIG: 120602747(RALGDS)
PVP: 105298674(RALGDS)
RAY: 107504584(RALGDS)
MJV: 108388220(RALGDS) 108390483
TOD: 119231221(RALGDS)
SARA: 101554760(RALGDS)
LAV: 100659236(RALGDS) 100674091
TMU: 101348205 101348938 101349734 101351825
ETF: 101654227(RALGDS)
DNM: 101411563 101411689 101412328(RALGDS) 101413433 101413494 101414344 101416511 101418699 101419028 101419675 101419801 101419900 101420394 101421543 101421938 101423539 101424175 101424964 101425018 101425147 101425228 101428037 101429523 101430859 101432719 101432932 101433374 101435973 101437183 101439197 101440090 101441865 101443536 101443821 101444389 101445955 101447303 105745277
MDO: 100017777(RALGDS)
GAS: 123233620(RALGDS)
SHR: 100917637(RALGDS)
AFZ: 127550939
PCW: 110205393(RALGDS)
OAA: 100080818(RALGDS)
GGA: 427758(RALGDS)
PCOC: 116234287(RALGDS)
MGP: 100543539(RALGDS)
CJO: 107321879(RALGDS)
TPAI: 128073234(RALGDS)
NMEL: 110406742(RALGDS)
APLA: 101799472(RALGDS)
ACYG: 106044092(RALGDS)
AFUL: 116497077(RALGDS)
TGU: 100221484(RALGDS)
LSR: 110477613(RALGDS)
SCAN: 103819134(RALGDS)
PMOA: 120512409(RALGDS)
OTC: 121336923(RALGDS)
PRUF: 121362421(RALGDS)
GFR: 102043791(RALGDS)
FAB: 101807597(RALGDS)
PHI: 102103696(RALGDS)
PMAJ: 107212012(RALGDS)
CCAE: 111937026(RALGDS)
CCW: 104688325(RALGDS)
CBRC: 103623254(RALGDS)
ETL: 114059093(RALGDS)
ZAB: 102073433(RALGDS)
ACHL: 103805569(RALGDS)
SVG: 106851363(RALGDS)
FPG: 101924202(RALGDS)
FCH: 102056619(RALGDS)
CLV: 102088221(RALGDS)
EGZ: 104129348(RALGDS)
NNI: 104023281(RALGDS)
PLET: 104619603(RALGDS)
PCRI: 104028822(RALGDS)
PCAO: 104051685(RALGDS)
ACUN: 113486640(RALGDS)
TALA: 104369586(RALGDS)
PADL: 103915354(RALGDS)
AFOR: 103905390(RALGDS)
ACHC: 115335131(RALGDS)
HALD: 104320308
HLE: 104834023(RALGDS)
AGEN: 126052274
GCL: 127023803
CCRI: 104162329(RALGDS)
CSTI: 104563525(RALGDS)
EHS: 104509521(RALGDS)
CMAC: 104486089(RALGDS)
BREG: 104643247
FGA: 104077412(RALGDS)
GSTE: 104256088
LDI: 104352375
OHA: 104329600(RALGDS)
NNT: 104404233(RALGDS)
SHAB: 115617115(RALGDS)
DPUB: 104296402(RALGDS)
PGUU: 104466327(RALGDS)
ACAR: 104532250(RALGDS)
CPEA: 104389914(RALGDS)
AVIT: 104280478(RALGDS)
CVF: 104292882(RALGDS)
CUCA: 104066933(RALGDS)
TEO: 104382134
BRHI: 104496246(RALGDS)
AAM: 106483747(RALGDS)
AROW: 112964231(RALGDS)
NPD: 112956025(RALGDS)
TGT: 104565742(RALGDS)
DNE: 112979940(RALGDS)
SCAM: 104138247(RALGDS)
ASN: 102367792(RALGDS)
AMJ: 102566192(RALGDS)
CPOO: 109313973(RALGDS)
GGN: 109292995(RALGDS)
PSS: 102455196(RALGDS)
CMY: 102937874(RALGDS)
CPIC: 101945651(RALGDS)
TST: 117889323(RALGDS)
CABI: 116824023(RALGDS)
MRV: 120386787(RALGDS)
ACS: 100562121(ralgds)
PVT: 110079654(RALGDS)
SUND: 121936280(RALGDS)
PBI: 103059380(RALGDS)
PMUR: 107299323(RALGDS)
CTIG: 120298892(RALGDS)
PGUT: 117656268(RALGDS)
PTEX: 113443804(RALGDS)
VKO: 123028321(RALGDS)
PMUA: 114588787(RALGDS)
ZVI: 118078366(RALGDS)
HCG: 128338951(RALGDS)
GJA: 107112792(RALGDS)
STOW: 125441553(RALGDS)
XLA: 108698864(ralgds.L) 108699930(ralgds.S)
XTR: 100135084(ralgds)
NPR: 108793321(RALGDS)
RTEM: 120914018(RALGDS)
BBUF: 120977960(RALGDS)
BGAR: 122945969(RALGDS)
DRE: 101885008 103909384 799483(ralgds)
SRX: 107711877 107717753 107724899 107734393
SANH: 107667531 107667907 107694528 107696901
SGH: 107573634 107574105 107600003 107602853
CCAR: 109084264 109084268(ralgds)
CAUA: 113083586 113088324 113090384 113090385 113096342
CGIB: 127941931 127962889 127986295 128018520
PTET: 122341023 122350504(ralgds)
LROH: 127162120 127169508(ralgds)
PPRM: 120461894 120484897(si:ch211-251j10.3)
MAMB: 125252397 125279683(ralgds)
CIDE: 127504009 127517961
MASI: 127415079 127424165 127428971 127430452 127446396
IPU: 108278782
PHYP: 113535717
SMEO: 124397884
TFD: 113643828
AMEX: 103041981
CMAO: 118819779
EEE: 113584565(ralgds)
TRU: 101067502(ralgds)
TNG: GSTEN00031001G001
LCO: 104934922(ralgds)
NCC: 104955348
CGOB: 115013182
ELY: 117253070
EFO: 125890778(ralgds)
SLUC: 116054237(si:ch211-251j10.3)
ECRA: 117945404
ESP: 116689159
PFLV: 114555259
GAT: 120830146
PPUG: 119224830
MSAM: 119892250
SCHU: 122875746
CUD: 121509834
ALAT: 119019381
MZE: 101479161(ralgds)
ONL: 100693157(ralgds)
OAU: 116316301
OLA: 101164630(ralgds)
OML: 112158957
XMA: 102237107(ralgds)
XCO: 114154167(ralgds)
XHE: 116730409(ralgds)
PRET: 103469838(ralgds)
PFOR: 103134913(ralgds)
PLAI: 106955954(ralgds)
PMEI: 106933326(ralgds)
GAF: 122828206
CVG: 107103647(ralgds)
CTUL: 119797460
GMU: 124877345
NFU: 107386081(rgl4)
KMR: 108242791
ALIM: 106521867(ralgds)
NWH: 119413800
AOCE: 111584014 111586344
MCEP: 125011835
CSEM: 103397014 103397399(rgl4)
POV: 109640300(ralgds)
SSEN: 122769758
HHIP: 117768474
HSP: 118114604(ralgds)
LCF: 108881628
SDU: 111238528(ralgds)
SLAL: 111645675(ralgds)
XGL: 120805828
HCQ: 109515584
SSCV: 125993996
BPEC: 110162079(ralgds)
MALB: 109957320(ralgds)
BSPL: 114861525
SASA: 106562829 106570436 106579966 106585456
STRU: 115159992 115164678 115199955 115203760
OTW: 112220069 112234556 112248341 112263063
OMY: 110509485 110523253 110525507 110535052
OGO: 123989409 124016638 124034428 124036173
ONE: 115111474 115119137 115139900 115147093
SALP: 111957831 111963773 111975184 112080611
SNH: 120021291 120026074 120060258 120063146
CCLU: 121541417 121550239 121582061 121584722
ELS: 105007891 105014171
SFM: 108921911 108932954
PKI: 111842082 111858727
AANG: 118212773 118237553
LOC: 102694251(ralgds)
PSPA: 121309690
ARUT: 117396931 117422410
PSEX: 120536021
LCM: 102354527(RGL2) 102360981(RALGDS)
CMK: 103183072
RTP: 109916669 109919061
CPLA: 122541250 122564935
RSAN: 119385867
 » show all
Reference
PMID:20478380
  Authors
Ferro E, Trabalzini L
  Title
RalGDS family members couple Ras to Ral signalling and that's not all.
  Journal
Cell Signal 22:1804-10 (2010)
DOI:10.1016/j.cellsig.2010.05.010
Reference
PMID:7972015
  Authors
Hofer F, Fields S, Schneider C, Martin GS
  Title
Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator.
  Journal
Proc Natl Acad Sci U S A 91:11089-93 (1994)
DOI:10.1073/pnas.91.23.11089
  Sequence
[hsa:5900]

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Ontology (2)   
   KEGG BRITE (1)   
   GO (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Gene (881)   
   KEGG GENES (597)   
   KEGG MGENES (156)   
   RefGene (123)   
   OC (5)   
Literature (2)   
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