KEGG ORTHOLOGY: K08757

ORTHOLOGY: K08757

Entry

K08757                      KO

Symbol

APOA1

Name

apolipoprotein A-I

Pathway

map03320

PPAR signaling pathway

map04975

Fat digestion and absorption

map04977

Vitamin digestion and absorption

map04979

Cholesterol metabolism

map05143

African trypanosomiasis

map05417

Lipid and atherosclerosis

Disease

H00845

Familial amyloidosis

H00930

Hypoalphalipoproteinemia

H02505

Atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K08757  APOA1; apolipoprotein A-I
  09154 Digestive system
   04975 Fat digestion and absorption
    K08757  APOA1; apolipoprotein A-I
   04979 Cholesterol metabolism
    K08757  APOA1; apolipoprotein A-I
   04977 Vitamin digestion and absorption
    K08757  APOA1; apolipoprotein A-I
09160 Human Diseases
  09174 Infectious disease: parasitic
   05143 African trypanosomiasis
    K08757  APOA1; apolipoprotein A-I
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K08757  APOA1; apolipoprotein A-I
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K08757  APOA1; apolipoprotein A-I
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other cancer cells
   K08757  APOA1; apolipoprotein A-I

Other DBs

GO:	0008035 0017127 0034190

Genes

HSA:	335(APOA1)

PTR:	107967226(APOA1)

PPS:	100990511(APOA1)

GGO:	101137897(APOA1)

PON:	100454832(APOA1)

NLE:	100599388(APOA1)

HMH:	116476975(APOA1)

MCC:	696969(APOA1)

MCF:	101925978(APOA1)

MTHB:

126936335

MNI:	105476442(APOA1)

CSAB:

103248547(APOA1)

CATY:

105582447(APOA1)

PANU:

100126737(APOA1)

TGE:	112605709(APOA1)

MLEU:

105541134(APOA1)

RRO:	104668900(APOA1)

RBB:	108536406(APOA1)

TFN:	117080433(APOA1)

PTEH:

111540177(APOA1)

CANG:

105501068(APOA1)

CJC:	100386212(APOA1)

SBQ:	101038607(APOA1)

CIMI:

108300558(APOA1)

CSYR:

103258195(APOA1)

MMUR:

105876085(APOA1)

LCAT:

123641549(APOA1)

PCOQ:

105821609(APOA1)

OGA:	100946639(APOA1)

MMU:	11806(Apoa1)

MCAL:

110302180(Apoa1)

MPAH:

110328699(Apoa1)

RNO:	25081(Apoa1)

MCOC:

116072189(Apoa1)

ANU:	117699369(Apoa1)

MUN:	110550120(Apoa1)

CGE:	100772590(Apoa1)

MAUA:

101841336(Apoa1)

PROB:

127231655(Apoa1)

PLEU:

114691212(Apoa1)

MORG:

121438404(Apoa1)

MFOT:

126510050

AAMP:

119808819(Apoa1)

NGI:	103748325(Apoa1)

HGL:	101725714(Apoa1)

CPOC:

100729378(Apoa1)

CCAN:

109699552(Apoa1)

DORD:

105980742(Apoa1)

DSP:	122110258(Apoa1)

NCAR:

124959826

OCU:	100009253(APOA1)

OPI:	101526234(APOA1)

TUP:	102500158(APOA1)

GVR:	103607177(APOA1)

CFA:	479427(APOA1)

CLUD:

112671278(APOA1)

VVP:	112920369(APOA1)

VLG:	121500144(APOA1)

AML:	100477643(APOA1)

UMR:	103662516(APOA1)

UAH:	113260022(APOA1)

UAR:	123792594(APOA1)

ELK:

111153700

LLV:

125079486

MPUF:

101689587(APOA1)

NVS:	122913982(APOA1)

ORO:	101382508(APOA1)

EJU:	114211307(APOA1)

ZCA:	113915030(APOA1)

MLX:	118013264(APOA1)

NSU:	110586240(APOA1)

LWW:	102732504(APOA1)

FCA:	101081076(APOA1)

PYU:	121035437(APOA1)

PBG:	122482999(APOA1)

LRUF:

124504796

PTG:	107179465(APOA1)

PPAD:

109278595(APOA1)

PUC:

125909516

AJU:	106966535(APOA1)

HHV:	120229945(APOA1)

BTA:	104974214 281631(APOA1)

BOM:	102285163(APOA1)

BIU:	109569690(APOA1)

BBUB:

102405498 123329842

BBIS:

104981342(APOA1)

CHX:	102179867 102180141(APOA1)

OAS:	101117785(APOA1)

ODA:	120859337 120859352(APOA1)

CCAD:

122450015(APOA1) 122450304

SSC:	397691(APOA1)

CFR:	102508000(APOA1)

CBAI:

105067841(APOA1)

CDK:	105090194(APOA1)

BACU:

103019302(APOA1)

LVE:	103070222(APOA1)

OOR:	101284590(APOA1)

DLE:	111166884(APOA1)

PCAD:

102992508(APOA1)

PSIU:

116757323(APOA1)

NASI:

112403983(APOA1)

ECB:	100062583(APOA1)

EPZ:	103548778(APOA1)

EAI:	106840253(APOA1)

MYB:	102250262(APOA1)

MYD:	102762628(APOA1)

MMYO:

118664277(APOA1)

MLF:	102438964(APOA1)

MNA:	107530785(APOA1)

PKL:	118713804(APOA1)

HAI:	109385280(APOA1)

DRO:	112314370(APOA1)

SHON:

119000582(APOA1)

AJM:	119054831(APOA1)

PDIC:

114498775(APOA1)

PHAS:

123818762(APOA1)

MMF:	118627592(APOA1)

RFQ:	117029836(APOA1)

PALE:

102879912(APOA1)

PGIG:

120622022(APOA1)

PVP:	105307621(APOA1)

RAY:	107505056(APOA1)

MJV:	108393363(APOA1)

TOD:	119239881(APOA1)

SARA:

101542214(APOA1)

LAV:	100675409(APOA1)

TMU:

101361966

ETF:	101640718(APOA1)

DNM:	101432754(APOA1)

MDO:	100031668(APOA1)

GAS:	123242087(APOA1)

SHR:	100928796(APOA1)

AFZ:

127555024

PCW:	110210641(APOA1)

OAA:	100087391(APOA1)

GGA:	396536(APOA1)

PCOC:

116232993(APOA1)

MGP:	100542499(APOA1)

CJO:	107324159(APOA1)

NMEL:

110387751(APOA1)

APLA:

101797140(APOA1)

ACYG:

106039769

AFUL:

116497846(APOA1)

TGU:	105758816(APOA1)

LSR:	110470417(APOA1)

SCAN:

103822973(APOA1)

PMOA:

120508438(APOA1)

OTC:	121340809(APOA1)

PRUF:

121353953(APOA1)

FAB:	101814498(APOA1)

PHI:	102109087(APOA1)

PMAJ:

107214448(APOA1)

CCAE:

111944323

CCW:	120411247(APOA1)

CBRC:

108447691(APOA1)

ETL:	114056296(APOA1)

SVG:	106858151(APOA1)

FPG:	101923245(APOA1)

FCH:	102058718(APOA1)

CLV:	102091117(APOA1)

EGZ:

104124569

NNI:

104015337

TALA:

116965718(APOA1)

AFOR:

103894412(APOA1)

ACHC:

115344665(APOA1)

HLE:	104836384(APOA1)

AGEN:

126038796

GCL:

127025739

LDI:

104344651

SHAB:

115616442(APOA1)

ACAR:

CPEA:

CVF:

CUCA:

AAM:	106497835(APOA1)

AROW:

112962097(APOA1)

NPD:

112948069

TGT:

104571429

DNE:

112987567

ASN:	102370247(APOA1)

AMJ:	109281450(APOA1)

CPOO:

109315422(APOA1)

GGN:	109294134(APOA1)

PSS:	102448084(APOA1)

CMY:	102943713(APOA1)

CPIC:

101934145(APOA1)

TST:	117868602(APOA1)

CABI:

116834171(APOA1)

MRV:	120375525(APOA1)

PVT:	110079009(APOA1) 110089446

SUND:

121935513(APOA1)

PBI:	103049626(APOA1)

PMUR:

107284791(APOA1)

CTIG:

120301967(APOA1)

TSR:

106556173

PGUT:

117670219(APOA1)

VKO:	123036817(APOA1)

PMUA:

114585628(APOA1)

ZVI:	118097188(APOA1)

GJA:	107124564(APOA1)

STOW:

125441662

XLA:	379086(apoa1.L) 379421(apoa1.S) 379735(XB5857568.L)

XTR:	100135198 448709(apoa1)

NPR:	108797071(APOA1)

RTEM:

120915109 120916060 120916599 120916600

BBUF:

120986831 120996244 120996251 120996258

BGAR:

122926270 122926913 122926914 122926915

DRE:	100101640(apoa1b) 30355(apoa1a)

SRX:	107720460 107734125 107746394 107750105

SANH:

107661262 107663408 107663743 107688065

SGH:	107551276 107575423 107596115 107599208

CCAR:

109055542 109073812 109074514 109109905

CAUA:

113049064 113058252 113077258 113115452

CGIB:

127972835 128003950

PPRM:

120464544(apoa1b) 120469691 120469692

MAMB:

125249313(apoa1b) 125266942(apoa1a)

CIDE:

127496277 127512952

MASI:

127422291 127429815 127429823 127435147

IPU:	100528199(apoa1a) 108280791 108280792

PHYP:

113531212 113542979 113542980

SMEO:

124379263(apoa1a) 124403183 124403273

TFD:	113652856 113652857 113662929 125138343

AMEX:

103026173

EEE:

113590495

TRU:	778012(apoa-i)

LCO:

104930449

CGOB:

115018293

MSAM:

119882545(apoa1b) 119911177

MZE:

101475711

ONL:

100708634

OAU:	116323688(apoa1b)

XMA:

XCO:

XHE:

PRET:

CVG:	107102713(apoa4)

CTUL:

119775425

NFU:

107395221

KMR:	108244443(apoa1b)

ALIM:

106530412(apoa4)

CSEM:

103378271

POV:	109634515(apoa4)

LCF:	108890650(apoa1b)

SDU:	111232800(apoa4)

SLAL:

111650622(apoa4) 111661079 111661085

XGL:	120792552(apoa1b)

HCQ:	109529424(apoa4)

BPEC:

110161978(apoa4)

MALB:

109951515

SASA:

100136573(APA11) 100196111(apoa1)

STRU:

115163137 115206084

OTW:	112265202 112266843

OMY:	100135864(apoa-i-1) 100135865(apoa-i-2)

OGO:	123992947 124006354

ONE:	115136968 115141622

SALP:

111949382 111960359 111981507

SNH:	120018335 120028919

CCLU:

121563638 121567489 121579977

ELS:	105011129(apoa4) 105026005

SFM:	108927234(apoa1)

PKI:

AANG:

LOC:

PSPA:

ARUT:

LCM:	102354735(APOA1)

CMK:

CPLA:

SCAC:

Reference

PMID:17107880

Authors

Obici L, Franceschini G, Calabresi L, Giorgetti S, Stoppini M, Merlini G, Bellotti V

Title

Structure, function and amyloidogenic propensity of apolipoprotein A-I.

Journal

Amyloid 13:191-205 (2006)
DOI:10.1080/13506120600960288

Reference

PMID:6294659

Authors

Breslow JL, Ross D, McPherson J, Williams H, Kurnit D, Nussbaum AL, Karathanasis SK, Zannis VI

Title

Isolation and characterization of cDNA clones for human apolipoprotein A-I.

Journal

Proc Natl Acad Sci U S A 79:6861-5 (1982)
DOI:10.1073/pnas.79.22.6861

Sequence

[hsa:335]

All links

Ontology (5)   
   KEGG BRITE (2)   
   GO (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (3)   
   KEGG DISEASE (3)   
Gene (511)   
   KEGG GENES (337)   
   RefGene (173)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (533)   

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