KEGG ORTHOLOGY: K09105

ORTHOLOGY: K09105

Entry

K09105                      KO

Symbol

TFE3

Name

transcription factor E3

Pathway

map04137

Mitophagy - animal

map05202

Transcriptional misregulation in cancer

map05211

Renal cell carcinoma

Disease

H00021

Renal cell carcinoma

H00051

Alveolar soft part sarcoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    K09105  TFE3; transcription factor E3
09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K09105  TFE3; transcription factor E3
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K09105  TFE3; transcription factor E3
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09105  TFE3; transcription factor E3
Transcription factors [BR:ko03000]
Eukaryotic type
  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
   Ubiquitous bHLH-ZIP factors
    K09105  TFE3; transcription factor E3

Genes

HSA:	7030(TFE3)

PTR:	473871(TFE3)

PPS:	100984828(TFE3)

GGO:	101125478(TFE3)

PON:	100456828(TFE3)

PPYG:

129024891(TFE3)

NLE:	100604394(TFE3)

HMH:	116811676(TFE3)

SSYN:

129475778(TFE3)

MCC:	712161(TFE3)

MCF:	102144652(TFE3)

MTHB:

126945571

MNI:	105493918(TFE3)

CSAB:

103231961(TFE3)

CATY:

105573117(TFE3)

PANU:

101015372(TFE3)

TGE:	112616010(TFE3)

MLEU:

105547709(TFE3)

RRO:	104661804(TFE3)

RBB:	108539574(TFE3)

TFN:	117077211(TFE3)

PTEH:

111533676

CANG:

105514999(TFE3)

CJC:	100415467(TFE3)

SBQ:	101030478(TFE3)

CIMI:

108298369(TFE3)

ANAN:

105730420(TFE3)

CSYR:

103268716(TFE3)

MMUR:

105856409(TFE3)

LCAT:

123628577(TFE3)

PCOQ:

105816779(TFE3)

OGA:	100960420(TFE3)

MMU:	209446(Tfe3)

MCAL:

110286603(Tfe3)

MPAH:

110313440(Tfe3)

RNO:	317376(Tfe3)

MCOC:

116103044(Tfe3)

ANU:	117694496(Tfe3)

ASYL:

127675011(Tfe3)

MUN:	110561989(Tfe3)

CGE:	100761176(Tfe3)

MAUA:

101832678(Tfe3)

PROB:

127218646(Tfe3)

PLEU:

114701294(Tfe3)

MORG:

121442603 121442681

MFOT:

126512816

AAMP:

119805091(Tfe3)

NGI:	103741661(Tfe3)

HGL:	101715111(Tfe3)

CPOC:

100733366(Tfe3)

CCAN:

109699888(Tfe3)

DORD:

105997833(Tfe3)

DSP:	122098791(Tfe3)

DMER:

138840354(Tfe3)

PLOP:

125343304(Tfe3)

NCAR:

124972452

MMMA:

107147450 107159840(Tfe3)

ITI:	101960841 101971451(Tfe3)

OCU:

100346824

OPI:	101534870(TFE3)

TUP:	102492524(TFE3)

GVR:	103589438(TFE3)

CFA:	491872(TFE3)

CLUD:

112673125(TFE3)

VVP:	112907233(TFE3)

VLG:	121483340(TFE3)

NPO:	129518782(TFE3)

AML:	100470680(TFE3)

UMR:	103668211(TFE3)

UAH:	113265941(TFE3)

UAR:	123797175(TFE3)

ELK:

111150460

LLV:

125091975

MPUF:

101683773(TFE3)

MNP:	132006660(TFE3)

MLK:	131821495(TFE3)

NVS:	122896907(TFE3)

ORO:	101384968(TFE3)

EJU:	114216789(TFE3)

ZCA:	113931088(TFE3)

MLX:	118010245(TFE3)

NSU:	110582911(TFE3)

LWW:	102738895(TFE3)

FCA:	101099025(TFE3)

PYU:	121025901(TFE3)

PCOO:

112871049(TFE3)

PBG:	122477965(TFE3)

PVIV:

125157667(TFE3)

LRUF:

124509525

LGF:	123594183(TFE3)

AJU:

106989005

PTG:	102970329(TFE3)

PPAD:

109248086(TFE3)

PUC:

125931673

HHV:	120221021(TFE3)

BTA:	520800(TFE3)

BOM:	102266511(TFE3)

BIU:	109555311(TFE3)

BBUB:

102404675(TFE3)

BBIS:

104982829

CHX:	102169369(TFE3)

OAS:	101106403(TFE3)

BTAX:

128069744(TFE3)

CSUM:

138070667(TFE3)

ODA:	120882114(TFE3)

CCAD:

122435086(TFE3)

MREE:

136153673(TFE3)

OVR:	110126844(TFE3)

MBEZ:

129534790(TFE3)

SSC:	100511298(TFE3)

CFR:	102508358(TFE3)

CBAI:

105079406(TFE3)

CDK:	105103295(TFE3)

VPC:	102538011(TFE3)

BACU:

103009619(TFE3)

BMUS:

118888815(TFE3)

LVE:	103078248(TFE3)

OOR:	101285380(TFE3)

LALB:

132512976(TFE3)

GMF:	115847122(TFE3)

DLE:	111169489(TFE3)

PCAD:

102996231(TFE3)

PSIU:

116747659(TFE3)

PPHC:

136143109(TFE3)

NASI:

112416015(TFE3)

ECB:	100051983(TFE3)

EPZ:	103544261(TFE3)

EAI:	106826972(TFE3)

MYB:	102257388(TFE3)

MYD:	102767749(TFE3)

MMYO:

118654060(TFE3)

MLF:	102431399(TFE3)

MDT:	132224944(TFE3)

PKL:	118731761(TFE3)

EFUS:

103301295(TFE3)

MNA:	107541383(TFE3)

DRO:	112322459(TFE3)

SHON:

118998335(TFE3)

AJM:	119059664(TFE3)

PDIC:

114504648(TFE3)

PHAS:

123832728(TFE3)

MMF:	118636390(TFE3)

PPAM:

129065209(TFE3)

HAI:	109374805(TFE3)

RFQ:	117024063(TFE3)

PALE:

102885286(TFE3)

PGIG:

120587075(TFE3)

PVP:	105309997(TFE3)

RAY:	107515012(TFE3)

MJV:	108396229(TFE3)

TOD:	119246166(TFE3)

SARA:

101546191(TFE3)

SFUM:

130036765(TFE3)

SETR:

125999196(TFE3)

LAV:	100676073(TFE3)

TMU:

101344296

ETF:	101638099(TFE3)

DNM:	101440616(TFE3)

MDO:	100019256(TFE3)

GAS:	123253591 123253993(TFE3)

SHR:	100919901(TFE3)

AFZ:

127542739

PCW:	110201082(TFE3)

PBRV:

138177171(TFE3)

MLAO:

141503023(TFE3)

OAA:	100076328(TFE3)

TACU:

119929751(TFE3)

GGA:	107049522(TFE3)

PCOC:

116240913(TFE3)

NMEL:

110391535

PMOA:

120513413

OTC:

121339156

PHI:	102102349(TFE3)

ACOE:

138100359

SHAB:

115602850(TFE3)

HHAR:

128138003(TFE3)

CBOY:

140645504

ASN:

102373591

AMJ:	109283989(TFE3)

PSS:

102460698

CMY:	102943023(TFE3)

CCAY:

125628231(TFE3)

DCC:	119846984(TFE3)

CPIC:

101951556(TFE3)

CABI:

116818910(TFE3)

MRV:	120388524(TFE3)

ACS:	100551955(tfe3)

ASAO:

132767804(TFE3)

PVT:	110081166(TFE3)

SUND:

121920783(TFE3)

PBI:	103068156(TFE3)

PMUR:

107292057(TFE3)

CTIG:

120309637(TFE3)

PGUT:

117675433(TFE3)

PCAE:

139312892(TFE3)

APRI:

131192585(TFE3)

PTEX:

113443351(TFE3)

NSS:	113417770(TFE3)

VKO:	123024055(TFE3)

PMUA:

114587522(TFE3)

PRAF:

128404751(TFE3)

ZVI:	118097742(TFE3)

HCG:	128342400(TFE3)

STOW:

125429168(TFE3)

EMC:	129346116(TFE3)

XLA:	108698087(tfe3.L) 495043(tfe3.S)

XTR:	100490005(tfe3)

NPR:	108789238(TFE3)

RTEM:

120913914(TFE3)

ACAT:

141108297(TFE3)

BBUF:

120977950(TFE3)

BGAR:

122929091 122946083

DTC:	141046654(TFE3)

PWL:	138260958(TFE3)

MUO:	115463469(TFE3)

GSH:	117349474(TFE3)

DRE:	114834(tfe3a) 564996(tfe3b)

SRX:	107727418 107727869 107743115 107749467

SANH:

107655047 107674333 107685675 107701807

SGH:	107552220 107563887 107584878 107598722

CCAR:

109068256 109074773(tfe3b) 109095190 109098516

CAUA:

113074167 113081179 113095888 113107025 113111148

CGIB:

127963594 127968263 128018962 128022301

PTET:

122350515(tfe3a) 122354274(tfe3b)

LROH:

127169564(tfe3a) 127173190(tfe3b)

GRF:	141286556(tfe3a) 141293450(tfe3b)

OMC:	131545701(tfe3a) 131549555(tfe3b)

PPRM:

120475102(tfe3a) 120480701(tfe3b)

RKG:	130085614(tfe3b) 130099541(tfe3a)

MAMB:

125256772(tfe3b) 125280041(tfe3a)

CIDE:

127517016 127522482

CERY:

137021532(tfe3b) 137026852(tfe3a)

MASI:

127415031 127424430 127426203 127427750

TROS:

130567617(tfe3a) 130570865(tfe3b)

TDW:	130407180(tfe3a) 130410216(tfe3b)

MANU:

129414145(tfe3a)

PDAB:

135718896(tfe3b) 135752054(tfe3a)

IPU:	108265526(tfe3a)

IFU:	128608182(tfe3a)

PHYP:

113535077(tfe3)

SMEO:

124399598(tfe3a)

TFD:	113645837(tfe3a)

TVC:	132853285(tfe3a)

CGAR:

128529798(tfe3a)

NGRA:

132893381(tfe3a)

TRN:	134318517(tfe3a)

AMEX:

103025463(tfe3b) 103028851(tfe3a)

CMAO:

118799328(tfe3b) 118813889(tfe3a)

EEE:	113575840 113586556(tfe3)

CHAR:

105899052(tfe3a) 105912251(tfe3b)

SPIL:

134087705(tfe3a) 134092902(tfe3b)

TRU:	101061097 101061212

TFS:	130524532(tfe3b) 130530301(tfe3a)

TNG:	GSTEN00014065G001

LCO:	104935491 104939489

NCC:	104945760(tfe3)

TBEN:

117474233 117475685(tfe3b)

CGOB:

115008092(tfe3)

PGEO:

117446594(tfe3b) 117449740

GACU:

117543745(tfe3b) 117558065(tfe3a)

EMAC:

134864458(tfe3a) 134882688(tfe3b)

ELY:	117257322(tfe3b) 117258187(tfe3a)

EFO:	125891671(tfe3a) 125891913(tfe3b)

PLEP:

121955543(tfe3b)

SLUC:

116036038(tfe3b) 116045500

ECRA:

117942918(tfe3b)

ESP:	116687323(tfe3)

PFLV:

114554869 114559336

GAT:	120814948(tfe3a) 120835475(tfe3b)

PPUG:

119223126(tfe3a) 119230167(tfe3b)

AFB:	129099698(tfe3a) 129105624(tfe3b)

CLUM:

117730763(tfe3b) 117733044(tfe3a)

PSWI:

130208621(tfe3b)

CANA:

137796008(tfe3b) 137801191(tfe3a)

CVE:	137879406(tfe3b) 137888686(tfe3a)

MSAM:

119885870(tfe3b) 119905532(tfe3a)

SCHU:

122862700(tfe3b) 122882514(tfe3a)

CUD:	121506830(tfe3b) 121517092(tfe3a)

SPUL:

138605431(tfe3b) 138608194(tfe3a)

LMIX:

132977693(tfe3b) 132990280(tfe3a)

ALAT:

119021540(tfe3b) 119022728(tfe3a)

ASTR:

137595441(tfe3b) 137602083(tfe3a)

MZE:	101477807 101488014

ONL:	100694045 100705007

OAU:	116314878(tfe3b) 116335446(tfe3a)

OLA:	101166296(tfe3) 101174799

OML:	112145756(tfe3b) 112158916(tfe3a)

CSAI:

133448988(tfe3b) 133456965(tfe3a)

XMA:	102225584(tfe3) 102231855

XCO:	114135530(tfe3) 114140718

XHE:	116710542(tfe3) 116723004

PRET:

103465541(tfe3)

PFOR:

103130740 103147339(tfe3)

PLAI:

106936400 106957360(tfe3)

PMEI:

106904754(tfe3) 106911306

GAF:	122833951(tfe3b) 122841086(tfe3a)

PPRL:

129355462(tfe3b)

CVG:	107099672(tfe3) 107100387

CTUL:

119790466(tfe3b) 119792015(tfe3a)

GMU:	124857279(tfe3b) 124871060(tfe3a)

NFU:	107385854(tfe3) 107391466

KMR:	108228826 108244409(tfe3b)

ALIM:

106531385(tfe3) 106533782

NWH:	119412298(tfe3b) 119417403

AOCE:

111573973(tfe3b) 111585597(tfe3a)

EJA:	138204175(tfe3b) 138215548(tfe3a)

BFRE:

138629924(tfe3b) 138631536

MCEP:

125006659(tfe3b) 125009211(tfe3a)

CSEM:

103384379(tfe3) 103386412

POV:	109629212 109643663

SSEN:

122768722(tfe3b) 122776830(tfe3a)

SSOE:

131460690(tfe3b) 131468565(tfe3a)

HHIP:

117761606(tfe3b) 117765238(tfe3a)

HSP:	118104686(tfe3b) 118111147(tfe3a)

PPLT:

128441804(tfe3a) 128448904(tfe3b)

SMAU:

118309339(tfe3b) 118316927(tfe3a)

LCF:	108885576 108890572(tfe3a)

SDU:	111221707 111235414

SLAL:

111649271(tfe3) 111654971

XGL:	120783378(tfe3b) 120803410(tfe3a)

HCQ:	109521480 109521547(tfe3)

SSCV:

125977215(tfe3b) 125989508(tfe3a)

SBIA:

133507834(tfe3b)

PEE:	133399207 133408536(tfe3b)

PTAO:

133474226 133483171(tfe3b)

BPEC:

110154465 110170162(tfe3)

ENY:	140363082 140365484(tfe3b)

MALB:

109953366 109956068

BSPL:

114855591(tfe3b) 114858618(tfe3a)

SJO:	128356046(tfe3b)

SSCO:

133977434(tfe3b) 133987618(tfe3a)

GMH:	115556568 115559765

SASA:

106565767 106566350 106582876

STRU:

115150845 115165274 115168729 115207578

OTW:	112215274 112219989 112237236 112254371

OMY:	110492701 110494570 110527898 110531290

OGO:	124031486 124032405 124045459

ONE:	115126839 115137427 115143383

OKI:	109890950 109897860 109908392

OKE:	118360653(tfe3a) 118380754 118388364 118400098(tfe3b)

OMM:	135503848 135527689 135540200(tfe3b) 135542143

OCLA:

139369004 139369880 139413361 139416966

SALP:

111969179 111969870 112073801 112077755

SNH:	120059049 120060206 120061461 120065061

CCLU:

121530834 121546181 121575016 121578256(tfe3b)

ELS:	105017371 105028322

OEP:	134019186(tfe3a)

SFM:	108918460 108934818

PKI:	111856146 111857008(tfe3)

AANG:

118207766(tfe3a)

AROT:

135235249(tfe3a)

CCOG:

133138288(tfe3a)

LOC:	102687259(tfe3)

PSPA:

121305536 121328877

ARUT:

117401593 117972119

PSEX:

120542024(tfe3a)

LCM:	102365950(TFE3)

HAKA:

140715970(tfe3a)

PMRN:

116942493

LRJ:	133349345 133355543

BBEL:

109477406

CIN:	778681(mitf)

SCLV:

SPU:

LPIC:

AJJ:

ARUN:

DAM:

PPYR:

MSEX:

DPL:	KGM_213896

MJU:

VCD:

MCIX:

PPOT:

PXU:

PRAP:

LSIN:

TNL:

SLIU:

OFU:

PXY:

PGW:

HVI:

MQU:	128998747 128998761

CSEC:

IEL:

AFRA:

PCHN:

HAME:

PTRU:

TCF:

PPOI:

DSV:

RSAN:

RMP:

CSCU:

CVS:

UDV:

SDM:

LPOL:

106462266 106464076 106470778

PMEO:

TSP:

BGT:

GAE:

HRJ:

HASI:

CRG:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

OSN:

LLON:

XEN:

RES:

Reference

PMID:11313942

Authors

Skalsky YM, Ajuh PM, Parker C, Lamond AI, Goodwin G, Cooper CS

Title

PRCC, the commonest TFE3 fusion partner in papillary renal carcinoma is associated with pre-mRNA splicing factors.

Journal

Oncogene 20:178-87 (2001)
DOI:10.1038/sj.onc.1204056

Reference

PMID:2338243

Authors

Beckmann H, Su LK, Kadesch T

Title

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

Journal

Genes Dev 4:167-79 (1990)
DOI:10.1101/gad.4.2.167

Sequence

[hsa:7030]

All links

Gene (180)   
   MGENES (112)   
   RefGene (66)   
   OC (2)   
All databases (180)   

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