Entry |
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Name |
putrescine---2-oxoglutarate transaminase;
putrescine-alpha-ketoglutarate transaminase;
YgjG;
putrescine:alpha-ketoglutarate aminotransferase;
PAT (ambiguous);
putrescine transaminase (ambiguous);
putrescine aminotransferase (ambiguous);
butane-1,4-diamine:2-oxoglutarate aminotransferase
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Class |
Transferases;
Transferring nitrogenous groups;
Transaminases
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Sysname |
putrescine:2-oxoglutarate aminotransferase
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Reaction(IUBMB) |
putrescine + 2-oxoglutarate = 1-pyrroline + L-glutamate + H2O (overall reaction) [RN: R10064];
(1a) putrescine + 2-oxoglutarate = 4-aminobutanal + L-glutamate [RN: R01155];
(1b) 4-aminobutanal = 1-pyrroline + H2O (spontaneous) [RN: R07408]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
A pyridoxal 5'-phosphate protein [3]. The product, 4-aminobutanal, spontaneously cyclizes to form 1-pyrroline, which is a substrate for EC 1.2.1.19, aminobutyraldehyde dehydrogenase. Cadaverine and spermidine can also act as substrates [3]. Forms part of the arginine-catabolism pathway [2]. cf. EC 2.6.1.113, putrescine---pyruvate transaminase.
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History |
EC 2.6.1.82 created 2006, modified 2017
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Pathway |
ec00330 | Arginine and proline metabolism |
ec01120 | Microbial metabolism in diverse environments |
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Orthology |
K09251 | putrescine aminotransferase |
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Genes |
» show all
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Reference |
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Authors |
Prieto-Santos MI, Martin-Checa J, Balana-Fouce R, Garrido-Pertierra A. |
Title |
A pathway for putrescine catabolism in Escherichia coli. |
Journal |
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Reference |
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Authors |
Samsonova NN, Smirnov SV, Novikova AE, Ptitsyn LR |
Title |
Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase. |
Journal |
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Reference |
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Authors |
Samsonova NN, Smirnov SV, Altman IB, Ptitsyn LR |
Title |
Molecular cloning and characterization of Escherichia coli K12 ygjG gene. |
Journal |
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Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: | 2.6.1.82 |
ExPASy - ENZYME nomenclature database: | 2.6.1.82 |
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