KEGG   ORTHOLOGY: K09587
Entry
K09587                      KO                                     
Symbol
CYP90B, DWF4
Name
steroid 22S-hydroxylase [EC:1.14.14.178]
Pathway
map00905  Brassinosteroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00371  Castasterone biosynthesis, campesterol => castasterone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00905 Brassinosteroid biosynthesis
    K09587  CYP90B, DWF4; steroid 22S-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K09587  CYP90B, DWF4; steroid 22S-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.178  steroid 22S-hydroxylase
     K09587  CYP90B, DWF4; steroid 22S-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP90 family
   K09587  CYP90B, DWF4; steroid 22S-hydroxylase
Other DBs
RN: R07430 R07445 R07452 R07453 R07454
Genes
ATH: AT3G50660(DWF4)
ALY: 9312109
CRB: 17885187
CSAT: 104780889 104791284
EUS: EUTSA_v10011005mg
BRP: 103828198 103840968
BNA: 106401625 106405681 106447365
BOE: 106310362 106321383
RSZ: 108809973 108826420 108826548
THJ: 104819220 104826953
CPAP: 110822261
CIT: 102623486
CIC: CICLE_v10025451mg
PVY: 116113019 116113135
MINC: 123199643 123199686 123214950
TCC: 18610945
GRA: 105803806
GHI: 107896149 107913065
GAB: 108471227
DZI: 111292390 111301072 111316237
EGR: 104419755
GMX: 100789515 100800210 100802498
GSJ: 114377375 114382291 114420632
PVU: PHAVU_002G029700g PHAVU_003G253100g
VRA: 106765911 106778030
VAR: 108334671 108335822
VUN: 114166425 114179641
CCAJ: 109801635 109810494
APRC: 113859349 113868805
MTR: 11405189 11408048
TPRA: 123908684 123920823
CAM: 101499755 101500152
PSAT: 127120259 127135353
LJA: Lj0g3v0324529.1(Lj0g3v0324529.1)
ADU: 107487855
AIP: 107642870
AHF: 112749146 112800701
LANG: 109331920 109348687
FVE: 101304220
RCN: 112187887
PPER: 18770032
PMUM: 103340078
PAVI: 110773452
PDUL: 117635807
MDM: 103401164 103401541
MSYL: 126604824 126613856
PXB: 103941521 103960819
ZJU: 107408367 107408382 107408649 107409125
MNT: 21395422
CSAV: 115714415
CSV: 101211854
CMO: 103494380
BHJ: 120069803
MCHA: 111008332
CMAX: 111479953
CMOS: 111446972
CPEP: 111807994
RCU: 8273425
HBR: 110634320 110665021
MESC: 110603714
POP: 18099286 18101214
PEU: 105110409 105126568
PALZ: 118030029 118063301
JRE: 108995250 108997500
CILL: 122297006 122307498
QSU: 112006212
QLO: 115994961
TWL: 120000980 120014527
VVI: 100241065
VRI: 117913676
SLY: 101256342(CYP90B3)
SPEN: 107009445
SOT: 102603786
SSTN: 125849264
CANN: 107859954
NTA: 107779615 107795954
NSY: 104210061
NTO: 104115826
NAU: 109210801
INI: 109168575
ITR: 116011693
SIND: 105177981
OEU: 111367619 111380525
EGT: 105954961
SSPL: 121767277 121772586
APAN: 127248819
HAN: 110915264
ECAD: 122579500
LSV: 111883587
CCAV: 112513520
DCR: 108220768
CSIN: 114274957
BVG: 104895859
SOE: 110797811
CQI: 110686172 110722522
NNU: 104595706 104601879
MING: 122073840 122083658
TSS: 122658580 122661166
PSOM: 113289235 113293814
OSA: 4332134
DOSA: Os03t0227700-01(Os03g0227700)
OBR: 102709630
OGL: 127768703
BDI: 100837605
ATS: 109742297 109786179
TDC: 119273638 119285031 119291093
TAES: 123059596 123066933 123075890 123085252 123092868 123098154
TUA: 125549501 125552395
LPER: 127296297
SBI: 8056846
ZMA: 100191562
SITA: 101770693
SVS: 117841038
PVIR: 120646755 120691708
PHAI: 112875152
PDA: 103697967 103704238 103707598 103707601 120113249
EGU: 105055939 105058149 105060750
MUS: 103974765 103981133 103996193 103996195
ZOF: 122008713 122011363 122013395 122014363 122015895 122026256 122026454 122027838 122028682 122030413 122030415 122032511 122034945
DCT: 110092799 110114079 110114986
PEQ: 110019548 110025965
AOF: 109833124 109834320 109834432
NCOL: 116260033
ATR: 18445832
 » show all
Reference
PMID:9490746
  Authors
Choe S, Dilkes BP, Fujioka S, Takatsuto S, Sakurai A, Feldmann KA
  Title
The DWF4 gene of Arabidopsis encodes a cytochrome P450 that mediates multiple 22alpha-hydroxylation steps in brassinosteroid biosynthesis.
  Journal
Plant Cell 10:231-43 (1998)
DOI:10.1105/tpc.10.2.231
  Sequence
[ath:AT3G50660]
Reference
PMID:16460510
  Authors
Fujita S, Ohnishi T, Watanabe B, Yokota T, Takatsuto S, Fujioka S, Yoshida S, Sakata K, Mizutani M.
  Title
Arabidopsis CYP90B1 catalyses the early C-22 hydroxylation of C27, C28 and C29 sterols.
  Journal
Plant J 45:765-74 (2006)
DOI:10.1111/j.1365-313X.2005.02639.x
  Sequence
[ath:AT3G50660]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
   KEGG RCLASS (1)   
Gene (222)   
   KEGG GENES (211)   
   KEGG MGENES (3)   
   RefGene (3)   
   OC (5)   
Literature (2)   
   PubMed (2)   
All databases (241)   

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KEGG   ORTHOLOGY: K12639
Entry
K12639                      KO                                     
Symbol
CYP724, D11
Name
steroid 22S-hydroxylase [EC:1.14.14.178]
Pathway
map00905  Brassinosteroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00371  Castasterone biosynthesis, campesterol => castasterone
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00905 Brassinosteroid biosynthesis
    K12639  CYP724, D11; steroid 22S-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K12639  CYP724, D11; steroid 22S-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.178  steroid 22S-hydroxylase
     K12639  CYP724, D11; steroid 22S-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP724 family
   K12639  CYP724, D11; steroid 22S-hydroxylase
Other DBs
RN: R07445 R07452 R07453 R07454
Genes
ATH: AT5G14400(CYP724A1)
ALY: 9307686
CRB: 17882948
CSAT: 104769675
EUS: EUTSA_v10015753mg
BRP: 103846487 103850927
BNA: 106364625 106370550 106417880
BOE: 106317102 106326221
RSZ: 108816728 108841135 108841282
THJ: 104802390
CPAP: 110808733 110808955
CIT: 102607509 102625685
CIC: CICLE_v10015033mg CICLE_v10017470mg
PVY: 116118304 116118306 116142804
MINC: 123195983 123216538 123222469
TCC: 18600875 18612531
GRA: 105779232 105803387
GHI: 107912480 107922960 107926035 107961481
GAB: 108460073 108472771
DZI: 111292725 111300505 111306191 111313510
EGR: 104419198 104420630
GMX: 100791737
GSJ: 114389140
PVU: PHAVU_008G147500g
CCAJ: 109793322
APRC: 113859482
MTR: 11437159
TPRA: 123893165
PSAT: 127128065
LJA: Lj2g3v0043650.1(Lj2g3v0043650.1)
LANG: 109350644
FVE: 101296274 101308903
RCN: 112183385 112187901
PPER: 18782463 18784320
PMUM: 103329118 103330155
PAVI: 110755657 110756001
PDUL: 117621138 117622631
MDM: 103405248 103429004 103442738
MSYL: 126609819 126634408 126634409
PXB: 103951781
ZJU: 107415245 107416825 107435422
MNT: 21400684
CSAV: 115699387 115700900
CSV: 101215045
CMO: 103498124
BHJ: 120079590
MCHA: 111006083
CMAX: 111487092
CMOS: 111430228
CPEP: 111808675
RCU: 8260354 8288322
JCU: 105634541 105643410
HBR: 110654062 110656526 110671515
MESC: 110602755 110605043 110629477
POP: 7467663 7469349
PEU: 105116030 105116836
PALZ: 118054146 118058119
JRE: 109009656
CILL: 122303891
QSU: 111993132 111999072 112023948
QLO: 115978378 115987302
TWL: 120011489
VVI: 100245690 100257922
VRI: 117926615 117931086
SLY: 101251900(CYP724B2) 101265305
SPEN: 107010789 107024375
SOT: 102582442
SSTN: 125847510 125847511 125877193
CANN: 107858413 107877366
NTA: 107776917 107795428 107801070 107825897
NSY: 104212166 104243183
NTO: 104100965 104104628
NAU: 109207893 109217467 109221822
INI: 109158109 109187712
ITR: 115998915 116011467
SIND: 105176862 105179881
OEU: 111389155
EGT: 105970780 105976276
SSPL: 121774314 121802385 121806412
APAN: 127240119 127258082
HAN: 110895233
ECAD: 122598110
LSV: 111918657
CCAV: 112516322
DCR: 108221483 108224415 108227649
CSIN: 114316234 114318951
NNU: 104591542 104608289
MING: 122078302 122094194
TSS: 122638371 122640557 122654025
PSOM: 113273094 113285824 113301538
OSA: 4336116
DOSA: Os04t0469800-01(Os04g0469800)
OBR: 102717238
OGL: 127769428
BDI: 100833643
ATS: 109734230
TDC: 119355441 119364561
TAES: 123045717 123053590 123189488
TUA: 125526986
LPER: 127335210
SBI: 8055423 8058684
ZMA: 100217085
SITA: 101768860 101769663
SVS: 117855539 117865849
PVIR: 120641205 120652021 120683428 120688207
PHAI: 112874677 112901555
PDA: 103721661
EGU: 105060809
MUS: 103981633 103983905
ZOF: 122045268
DCT: 110112973
AOF: 109840188
NCOL: 116249569 116259560
ATR: 18447481 18448244
 » show all
Reference
PMID:15705958
  Authors
Tanabe S, Ashikari M, Fujioka S, Takatsuto S, Yoshida S, Yano M, Yoshimura A, Kitano H, Matsuoka M, Fujisawa Y, Kato H, Iwasaki Y
  Title
A novel cytochrome P450 is implicated in brassinosteroid biosynthesis via the characterization of a rice dwarf mutant, dwarf11, with reduced seed length.
  Journal
Plant Cell 17:776-90 (2005)
DOI:10.1105/tpc.104.024950
  Sequence
[osa:4336116]
Reference
PMID:16960392
  Authors
Ohnishi T, Watanabe B, Sakata K, Mizutani M.
  Title
CYP724B2 and CYP90B3 function in the early C-22 hydroxylation steps of brassinosteroid biosynthetic pathway in tomato.
  Journal
Biosci Biotechnol Biochem 70:2071-80 (2006)
DOI:10.1271/bbb.60034
  Sequence
[sly:101251900]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
   KEGG RCLASS (1)   
Gene (214)   
   KEGG GENES (205)   
   KEGG MGENES (2)   
   RefGene (2)   
   OC (5)   
Literature (2)   
   PubMed (2)   
All databases (232)   

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