KEGG ORTHOLOGY: K09594

ORTHOLOGY: K09594

Entry

K09594                      KO

Symbol

FLCN, BHD

Name

folliculin

Pathway

map04150

mTOR signaling pathway

map05211

Renal cell carcinoma

Disease

H00020

Colorectal cancer

H00021

Renal cell carcinoma

H00818

Birt-Hogg-Dube syndrome

H01110

Pneumothorax

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04150 mTOR signaling pathway
    K09594  FLCN, BHD; folliculin
09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K09594  FLCN, BHD; folliculin

Other DBs

GO:

0005085

Genes

HSA:	201163(FLCN)

PTR:	454472(FLCN)

PPS:	100980236(FLCN)

GGO:	101136366(FLCN)

PON:	100431335(FLCN)

PPYG:

129018058(FLCN)

NLE:	100598314(FLCN)

HMH:	116483424(FLCN)

SSYN:

129461662(FLCN)

MCC:	698082(FLCN)

MCF:	102130800(FLCN)

MTHB:

126938799

MNI:	105491074(FLCN)

CSAB:

103242467(FLCN)

CATY:

105598187(FLCN)

PANU:

101007756(FLCN)

TGE:	112609661(FLCN)

MLEU:

105536000(FLCN)

RRO:	104668268(FLCN)

RBB:	108544476(FLCN)

TFN:	117067590(FLCN)

PTEH:

111529222(FLCN)

CANG:

105518990(FLCN)

CJC:	100395467(FLCN)

SBQ:	101050343(FLCN)

CIMI:

108295288(FLCN)

ANAN:

105709861(FLCN)

CSYR:

103274546(FLCN)

MMUR:

105856333(FLCN) 105857532 105867560

LCAT:

123650945(FLCN)

PCOQ:

105816125(FLCN)

OGA:	100953828(FLCN)

MMU:	216805(Flcn)

MCAL:

110305887(Flcn)

MPAH:

110331410(Flcn)

RNO:	303185(Flcn)

MCOC:

116077775(Flcn)

ANU:	117711115(Flcn)

MUN:	110549988(Flcn)

CGE:	100760396(Flcn)

MAUA:

101829319(Flcn)

PROB:

127219206(Flcn)

PLEU:

114682581(Flcn)

MORG:

121457113(Flcn)

MFOT:

126514599

AAMP:

119812684(Flcn)

NGI:	103743385(Flcn)

HGL:	101709729(Flcn)

CPOC:

100729986(Flcn)

CCAN:

109698422(Flcn)

DORD:

105985849(Flcn)

DSP:	122103365(Flcn)

PLOP:

125365106(Flcn)

NCAR:

124979045 124988079

MMMA:

107157150(Flcn)

OCU:

100341231

OPI:	101527359(FLCN)

TUP:	102502763(FLCN)

GVR:	103600027(FLCN)

CFA:	479529(FLCN)

CLUD:

112647233(FLCN)

VVP:	112924971(FLCN)

VLG:	121500046(FLCN)

NPO:	129497292(FLCN)

AML:	100470222(FLCN)

UMR:	103658481(FLCN)

UAH:	113271307(FLCN)

UAR:	123779718(FLCN)

ELK:

111139249

LLV:

125087078

MPUF:

101684132(FLCN)

MNP:	132004560(FLCN)

MLK:	131816110(FLCN)

NVS:	122906848(FLCN)

ORO:	101371328 101376827(FLCN)

EJU:	114196661 114198187(FLCN)

ZCA:	113925605 113939237(FLCN)

MLX:	118000161(FLCN)

NSU:	110584516(FLCN)

LWW:	102749494(FLCN)

FCA:	101081509(FLCN)

PYU:	121015793(FLCN)

PCOO:

112857111(FLCN)

PBG:	122485059(FLCN)

PVIV:

125151285(FLCN)

LRUF:

124519490

PTG:	102950823(FLCN)

PPAD:

109245760(FLCN)

PUC:

125927547

AJU:

106981429

HHV:	120228787(FLCN)

BTA:	526652(FLCN)

BOM:	102268877(FLCN)

BIU:	109573690(FLCN)

BBUB:

102392664(FLCN)

BBIS:

104990654(FLCN)

CHX:	102184091(FLCN)

OAS:	101121947(FLCN)

BTAX:

128064832(FLCN)

ODA:	120867373(FLCN)

CCAD:

122443811(FLCN)

MBEZ:

129544234(FLCN)

SSC:	110256140(FLCN)

CFR:	102522589(FLCN)

CBAI:

105082011(FLCN)

CDK:	105100589(FLCN)

VPC:	102531324(FLCN)

BACU:

103015269(FLCN)

BMUS:

118887403(FLCN)

LVE:	103069606(FLCN)

OOR:	101277086(FLCN)

DLE:	111167696(FLCN)

PCAD:

102995227

PSIU:

116745212(FLCN)

NASI:

112404365(FLCN)

ECB:	100052790(FLCN)

EPZ:	103566547(FLCN)

EAI:	106840675(FLCN)

MYB:	102261787(FLCN)

MYD:	102760294(FLCN)

MMYO:

118649349(FLCN)

MLF:	102438279(FLCN)

MDT:	132217903(FLCN) 132235866

PKL:	118726871(FLCN)

EFUS:

103299340(FLCN)

MNA:	107539205(FLCN)

DRO:	112308466(FLCN)

SHON:

119002716(FLCN)

AJM:	119062253(FLCN)

PDIC:

114515116(FLCN)

PHAS:

123809215(FLCN)

MMF:	118641305(FLCN)

PPAM:

129068743(FLCN)

HAI:	109390356(FLCN)

RFQ:	117013273(FLCN)

PALE:

102883717(FLCN)

PGIG:

120589881(FLCN)

PVP:	105291339(FLCN)

MJV:	108391550(FLCN)

TOD:	119230352 119231524

SARA:

101558078(FLCN)

SETR:

126013682(FLCN)

LAV:	100666966(FLCN)

TMU:

101354526

ETF:	101641559(FLCN)

DNM:	101433678(FLCN)

MDO:	100009804(FLCN)

GAS:	123235514(FLCN)

SHR:	100931207(FLCN)

AFZ:

127562073

PCW:	110194783(FLCN)

TVP:	118832078(FLCN)

OAA:	100078773(FLCN)

GGA:	416503(FLCN)

PCOC:

116237683(FLCN)

MGP:	100541833(FLCN)

CJO:	107320595(FLCN)

TPAI:

128079398(FLCN)

LMUT:

125700999(FLCN)

NMEL:

110405814(FLCN)

APLA:

101793020(FLCN)

ACYG:

106032102(FLCN)

CATA:

118256355(FLCN)

AFUL:

116495358(FLCN)

TGU:	100225078(FLCN)

LSR:	110481333(FLCN)

SCAN:

103817605(FLCN)

PMOA:

120513177(FLCN)

OTC:	121334572(FLCN)

PRUF:

121350621(FLCN)

GFR:	102041065(FLCN)

FAB:	101806701(FLCN)

OMA:	130259510(FLCN)

PHI:	102110891(FLCN)

PMAJ:

107211389(FLCN)

CCAE:

111936135(FLCN)

CCW:	104684782(FLCN)

CBRC:

103615399(FLCN)

ETL:	114065953(FLCN)

ZAB:	102070712(FLCN)

ZLE:	135454245(FLCN)

ACHL:

103804044(FLCN)

SVG:	106849990(FLCN)

MMEA:

130575691(FLCN)

HRT:	120759591(FLCN)

SATI:

136367959(FLCN)

FPG:	101915071(FLCN)

FCH:	102053510(FLCN)

CCRI:

104155593(FLCN)

NNT:	104402788(FLCN)

SHAB:

115607187(FLCN)

ACUN:

113485705(FLCN)

TALA:

104356078(FLCN)

ACHC:

115335874(FLCN)

HALD:

104311593(FLCN)

HLE:	104833602(FLCN)

AGEN:

126034098

GCL:

127022422

CSTI:

104558176(FLCN)

LDI:	104352084(FLCN)

MNB:	103778484(FLCN)

DPUB:

104296895(FLCN)

AVIT:

104275720(FLCN)

BRHI:

104494554(FLCN)

EGZ:	104123094(FLCN)

NNI:	104015115(FLCN)

PCRI:

104035728(FLCN)

PCAO:

104041408(FLCN)

PADL:

103918792(FLCN)

AFOR:

103904900(FLCN)

FGA:	104074087(FLCN)

GSTE:

104251508(FLCN)

CLV:	102084349(FLCN)

MUI:	104534083(FLCN)

PGUU:

104458899(FLCN)

PLET:

104614651(FLCN)

EHS:	104516447(FLCN)

CMAC:

104474008(FLCN)

CUCA:

104062500(FLCN)

TEO:	104370400(FLCN)

BREG:

104638743(FLCN)

OHA:	104335657(FLCN)

ACAR:

104530376(FLCN)

CPEA:

104385268(FLCN)

CVF:	104290135(FLCN)

RTD:	128913354(FLCN)

AAM:	106487294(FLCN)

AROW:

112974313(FLCN)

NPD:	112960070(FLCN)

TGT:	104580140(FLCN)

DNE:	112980420(FLCN)

SCAM:

104150818(FLCN)

ASN:	102381805(FLCN)

AMJ:	102561109(FLCN)

CPOO:

109314677(FLCN)

GGN:	109294345(FLCN)

PSS:	102446368(FLCN)

CMY:	102941273(FLCN)

CCAY:

125644409(FLCN)

DCC:	119862939(FLCN)

CPIC:

101932034(FLCN)

TST:	117884054(FLCN)

CABI:

116814813(FLCN)

MRV:	120373810(FLCN)

ACS:	100551569(flcn)

ASAO:

132782127(FLCN)

PVT:	110071096(FLCN)

SUND:

121914845(FLCN)

PBI:	103054922(FLCN)

PMUR:

107289144(FLCN)

CTIG:

120319315(FLCN)

TSR:	106555812(FLCN)

PGUT:

117679536(FLCN)

APRI:

131185089(FLCN)

PTEX:

113438831(FLCN)

NSS:	113422340(FLCN)

VKO:	123025096(FLCN)

PMUA:

114584708(FLCN)

PRAF:

128402207(FLCN)

ZVI:	118093115(FLCN)

HCG:	128336842(FLCN)

GJA:	107124235(FLCN)

STOW:

125431738(FLCN)

EMC:	129338792(FLCN)

XLA:	100158392(flcn.S)

XTR:	496819(flcn)

NPR:	108800643(FLCN)

RTEM:

120943193(FLCN)

BBUF:

121008262(FLCN)

BGAR:

122944678(FLCN)

MUO:	115476555(FLCN)

GSH:	117369010(FLCN)

DRE:	678628(flcn)

SRX:

107750008

SANH:

107673020 107692552

SGH:	107549459 107598420

CCAR:

109112605(flcn)

CAUA:

113059489 113116342(flcn)

CGIB:

127974836 128030214

PTET:

122360998(flcn)

LROH:

127178825(flcn)

OMC:	131522259(flcn)

PPRM:

120469860(flcn)

RKG:	130104030(flcn)

MAMB:

125243110(flcn)

CIDE:

127496761

CERY:

137031760(flcn)

MASI:

127453752

TROS:

130557475(flcn)

TDW:	130433422(flcn)

MANU:

129447844(flcn)

IPU:

108266904

IFU:	128608603(flcn)

PHYP:

113542311(flcn)

SMEO:

124384391(flcn)

TFD:	113643407(flcn)

TVC:	132846025(flcn)

TRN:	134310823(flcn)

AMEX:

103032296(flcn)

CMAO:

118825256(flcn)

EEE:	113570667(flcn)

CHAR:

105894822(flcn)

TRU:	101074538(flcn)

TFS:	130532952(flcn)

TNG:	GSTEN00015407G001

LCO:	104929739(flcn)

NCC:	104960444(flcn)

TBEN:

117480648(flcn)

CGOB:

115021215(flcn)

PGEO:

117460471(flcn)

GACU:

117533434(flcn)

EMAC:

134861812(flcn)

ELY:	117265833(flcn)

EFO:	125893813(flcn)

PLEP:

121946264(flcn)

SLUC:

116049625(flcn)

ECRA:

117946222(flcn)

ESP:	116691578(flcn)

PFLV:

114557105(flcn)

GAT:	120811041(flcn)

PPUG:

119197739(flcn)

AFB:	129109663(flcn)

CLUM:

117745237(flcn)

PSWI:

130212589(flcn)

MSAM:

119897510(flcn)

SCHU:

122881121(flcn)

CUD:	121513866(flcn)

ALAT:

119005444(flcn)

MZE:	101475784(flcn)

ONL:	100692007(flcn)

OAU:	116323842(flcn)

OLA:	101163763(flcn)

OML:	112143367(flcn)

CSAI:

133433518(flcn)

XMA:	102225177(flcn)

XCO:	114141710(flcn)

XHE:	116717344(flcn)

PRET:

103478075(flcn)

PFOR:

103136657(flcn)

PLAI:

106953525(flcn)

PMEI:

106925383(flcn)

GAF:	122830537(flcn)

PPRL:

129371105(flcn)

CVG:	107088819(flcn)

CTUL:

119782992(flcn)

GMU:	124865690(flcn)

NFU:	107379556(flcn)

KMR:	108235527(flcn)

ALIM:

106520527(flcn)

NWH:	119409984(flcn)

AOCE:

111572055(flcn) 111578674

MCEP:

125015966(flcN)

CSEM:

103387845(flcn)

POV:	109633270(flcn)

SSEN:

122775219(flcn)

HHIP:

117776174(flcn)

HSP:	118114106(flcn)

PPLT:

128449089(flcn)

SMAU:

118303162(flcn)

LCF:

108887287

SDU:	111229983(flcn)

SLAL:

111669934(flcn)

XGL:	120784203(flcn)

HCQ:	109515353(flcn)

SSCV:

125975700

SBIA:

133501244(flcn)

PEE:	133401477(flcn)

PTAO:

133478977(flcn)

BPEC:

110163052(flcn)

MALB:

109970237(flcn)

BSPL:

114843340(flcn)

SJO:	128365946(flcn)

SASA:

106577129 106605767

STRU:

115177316 115188810

OTW:	112234885 112243945(flcn)

OMY:	110508803(flcn) 110536927

OGO:	123998154 124005120

ONE:	115113796 115119451

OKI:	109885329 109905978

OKE:	118375179(flcn) 118377388

SALP:

112072282 112074672

SNH:	120030825 120048737

CCLU:

121542918 121556505

ELS:	105019009(flcn)

SFM:	108924470(flcn)

PKI:	111853343(flcn)

AANG:

118229352(flcn)

PSPA:

121302364(flcn)

ARUT:

117410057 117968440 117970380

PSEX:

120518439(flcn)

LCM:	102363066(FLCN)

PMRN:

116949529(FLCN)

LRJ:	133346201(FLCN)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG8616(BHD)

DER:

6544708

DSE:

6611109

DSI:	Dsimw501_GD14000(Dsim_GD14000)

DYA:	Dyak_GE21600

DAN:

6507642

DSR:

110186781

DPO:	117184393 4813717

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13239

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

AOQ:

TDA:	119668548 119672547 119673072 119673136

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

134202196 134204321 134218053

CQU:	CpipJ_CPIJ000204

CPII:

CNS:

BCOO:

CCAL:

MGEN:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105675604(BHD)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:	103579452 106694194

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

AROA:

TCA:

DPA:

SOY:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_212974

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:	110377968(bhd)

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

NLU:

HVI:

MQU:	128997655 129003627 129003645

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

DPX:	DAPPUDRAFT_318081

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

CSCU:

CVS:	136988502(BHD)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F22D3.2(flcn-1)

CBR:	CBG_11189 CBG_11190

CRQ:	GCK72_006384

NAI:	NECAME_12541 NECAME_12542

BMY:	BM_BM3513(Bma-flcn-1)

LOA:	LOAG_03765

HRO:	HELRODRAFT_107810

LGI:	LOTGIDRAFT_186179

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:	106166667 106169146

SMM:	Smp_176040

OVI:	T265_00896

EGL:

EGR_01112

LLON:

135492204

NVE:

116620270

EPA:	110232269 110235256

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_53485

AQU:

100633556

RIE:	OCT59_016679

» show all

Reference

PMID:12204536

Authors

Nickerson ML, Warren MB, Toro JR, Matrosova V, Glenn G, Turner ML, Duray P, Merino M, Choyke P, Pavlovich CP, Sharma N, Walther M, Munroe D, Hill R, Maher E, Greenberg C, Lerman MI, Linehan WM, Zbar B, Schmidt LS

Title

Mutations in a novel gene lead to kidney tumors, lung wall defects, and benign tumors of the hair follicle in patients with the Birt-Hogg-Dube syndrome.

Journal

Cancer Cell 2:157-64 (2002)
DOI:10.1016/S1535-6108(02)00104-6

Sequence

[hsa:201163]

All links

Ontology (2)   
   KEGG BRITE (1)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (4)   
   KEGG DISEASE (4)   
Gene (1252)   
   KEGG GENES (642)   
   KEGG MGENES (170)   
   RefGene (437)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (1263)   

Download RDF

DBGET integrated database retrieval system