KEGG   ORTHOLOGY: K09667
Entry
K09667                      KO                                     

Name
OGT
Definition
protein O-GlcNAc transferase [EC:2.4.1.255]
Pathway
ko00514  Other types of O-glycan biosynthesis
ko04931  Insulin resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    K09667  OGT; protein O-GlcNAc transferase
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K09667  OGT; protein O-GlcNAc transferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K09667  OGT; protein O-GlcNAc transferase
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K09667  OGT; protein O-GlcNAc transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.255  protein O-GlcNAc transferase
     K09667  OGT; protein O-GlcNAc transferase
Glycosyltransferases [BR:ko01003]
 O-Glycan biosynthesis
  O-linked GlcNAc type
   K09667  OGT; protein O-GlcNAc transferase
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    NSL complex
     K09667  OGT; protein O-GlcNAc transferase
Other DBs
RN: R09304 R09676
GO: 0097363
CAZy: GT41
Genes
HSA: 8473(OGT)
PTR: 465702(OGT)
PPS: 100989146(OGT)
GGO: 101140533(OGT)
NLE: 100591966(OGT)
MCC: 698268(OGT)
MCF: 101866582(OGT)
CSAB: 103232164(OGT)
RRO: 104664903(OGT)
RBB: 108527587(OGT)
CJC: 100386886(OGT)
SBQ: 101045971(OGT)
MMU: 108155(Ogt)
MCAL: 110286164(Ogt)
MPAH: 110313595(Ogt)
RNO: 26295(Ogt)
MUN: 110540923(Ogt)
CGE: 100768670(Ogt)
NGI: 103751946(Ogt)
HGL: 101710902 101721730(Ogt)
CCAN: 109699231(Ogt)
OCU: 100354727(OGT)
TUP: 102479359(OGT)
CFA: 480955(OGT)
VVP: 112907620(OGT)
AML: 100475282(OGT)
UMR: 103682584(OGT)
UAH: 113245624(OGT)
ORO: 101369290(OGT)
ELK: 111161042
FCA: 101094162(OGT)
PTG: 102964072(OGT)
PPAD: 109254620(OGT)
AJU: 106982362(OGT)
BTA: 532053(OGT)
BOM: 102286677(OGT)
BIU: 109555132
BBUB: 102397041(OGT)
CHX: 102187305(OGT)
OAS: 101106996(OGT)
SSC: 664652(OGT)
CFR: 102516733(OGT)
CDK: 105087990(OGT)
BACU: 103019745 103020800(OGT)
LVE: 103073601(OGT)
OOR: 101282914(OGT)
DLE: 111167771(OGT)
ECB: 100056148(OGT)
EPZ: 103542615(OGT)
EAI: 106828870(OGT)
MYB: 102245549(OGT)
MYD: 102773180(OGT)
MNA: 107532885(OGT)
HAI: 109385597(OGT)
DRO: 112300108(OGT)
PALE: 102890872(OGT)
RAY: 107513897(OGT)
MJV: 108396625(OGT)
LAV: 100662852(OGT)
TMU: 101341664
MDO: 100011073(OGT)
SHR: 100929019(OGT)
PCW: 110201103(OGT)
OAA: 103169766(OGT)
GGA: 422203(OGT)
MGP: 100538830(OGT)
CJO: 107312490(OGT)
NMEL: 110403357(OGT)
APLA: 101799851(OGT)
ACYG: 106037709(OGT)
TGU: 100224237(OGT)
LSR: 110472655(OGT)
SCAN: 103824224(OGT)
GFR: 102044727(OGT)
FAB: 101808611(OGT)
PHI: 102112943(OGT)
PMAJ: 107203795(OGT)
CCAE: 111929384(OGT)
CCW: 104691638(OGT)
ETL: 114066210(OGT)
FPG: 101915918(OGT)
FCH: 102052264(OGT)
CLV: 102092523(OGT)
EGZ: 104124274(OGT)
NNI: 104012908(OGT)
ACUN: 113479886(OGT)
PADL: 103923339(OGT)
AAM: 106482679(OGT)
ASN: 102387350(OGT)
AMJ: 102575029(OGT)
PSS: 102445994(OGT)
CMY: 102932353
CPIC: 101937402(OGT)
ACS: 100561277(ogt)
PVT: 110080200(OGT)
PBI: 103059316(OGT)
PMUR: 107303237(OGT)
TSR: 106552555(OGT)
PMUA: 114588797(OGT)
GJA: 107108561(OGT)
XLA: 447694(ogt.L)
XTR: 553157(ogt)
NPR: 108802573(OGT)
DRE: 337685(ogt.1) 652952(ogt.2)
SANH: 107663079(ogt) 107688794
CCAR: 109102899
IPU: 108268666(ogt)
PHYP: 113542871(ogt)
AMEX: 103028765(ogt)
EEE: 113576512(ogt)
TRU: 101076057(ogt)
LCO: 104923189(ogt)
NCC: 104952211(ogt)
MZE: 101479094(ogt)
ONL: 100697871(ogt)
OLA: 101164571(ogt)
XMA: 102227742(ogt)
XCO: 114139527(ogt)
PRET: 103471170(ogt)
CVG: 107089044(ogt)
NFU: 107395869(ogt)
KMR: 108240572(ogt)
ALIM: 106515959(ogt)
AOCE: 111565562(ogt)
CSEM: 103391144(ogt)
POV: 109626074(ogt)
LCF: 108882891(ogt)
SDU: 111226555(ogt)
SLAL: 111652072(ogt)
HCQ: 109515817(ogt)
BPEC: 110163678(ogt)
MALB: 109968379(ogt)
SASA: 100380730(ogt1) 106604253
SALP: 112069184(ogt)
ELS: 105025795(ogt)
PKI: 111843708(ogt)
LCM: 102361281(OGT)
CMK: 103189357(ogt)
RTP: 109935524(ogt)
CIN: 100181206
SPU: 579289
APLC: 110979775
SKO: 100370331
DME: Dmel_CG10392(sxc)
DER: 6542086
DSE: 6620741
DSI: Dsimw501_GD17889(Dsim_GD17889) Dsimw501_GD28381(Dsim_GD28381)
DAN: 6496811
DSR: 110189830
DPE: 6603520
DWI: 6640415
DAZ: 108616077
DNV: 108652808
DHE: 111600032
DVI: 6625793
MDE: 101896707
LCQ: 111678054
AAG: 5576163
AALB: 109408004
AME: 551425
BIM: 100743649
BTER: 100650322
CCAL: 108625753
SOC: 105204720
MPHA: 105837376
AEC: 105154372
ACEP: 105623805
PBAR: 105426065
VEM: 105558008
HST: 105190539
DQU: 106750329
CFO: 105255034
LHU: 105674563
PGC: 109858518
OBO: 105288176
PCF: 106792175
NVI: 100116809(Ogt)
CSOL: 105360543
MDL: 103572800
TCA: 655930
DPA: 109545225
ATD: 109601600
NVL: 108562050
BTAB: 109034308
CLEC: 106669648
ZNE: 110837287
PVM: 113825049
TUT: 107364202
DPTE: 113790022
CSCU: 111635493
PTEP: 107442002
CEL: CELE_K04G7.3(ogt-1)
CBR: CBG16605(Cbr-ogt-1)
BMY: Bm1_01735
TSP: Tsp_01535
PCAN: 112559301
CRG: 105329715
OBI: 106875699
LAK: 106156607
SHX: MS3_06840
EGL: EGR_08361
NVE: 5519150
EPA: 110251629
ADF: 107348213
AMIL: 114955646
PDAM: 113686986
SPIS: 111344576
DGT: 114521268
HMG: 100201589
AQU: 100633595
ATH: AT3G04240(SEC) AT3G11540(SPY)
LJA: Lj5g3v0803050.1(Lj5g3v0803050.1) Lj5g3v1303350.1(Lj5g3v1303350.1) Lj5g3v1303350.2(Lj5g3v1303350.2)
DOSA: Os02t0489550-00(Os02g0489550) Os08t0559300-01(Os08g0559300)
ATS: 109763129(LOC109763129) 109782465(LOC109782465)
ZMA: 100191509(pco141552) 100381672(cl27878_1(278))
CRE: CHLREDRAFT_117813(OGT1)
MNG: MNEG_0970
DDI: DDB_G0285263(spyA)
DFA: DFA_05779(spyA)
CPV: cgd1_1300
SMIN: v1.2.002533.t1(symbB.v1.2.002533.t1) v1.2.015572.t2(symbB.v1.2.015572.t2) v1.2.023338.t1(symbB.v1.2.023338.t1)
DKO: I596_1643
MCA: MCA1509
AEH: Mlg_0699
CSA: Csal_1986
APAC: S7S_17190
SLIM: SCL_1574
SVA: SVA_1487
SALN: SALB1_1846
TBN: TBH_C0586
RSY: RSUY_33650(yrrB_2)
BGO: BM43_4753
BFN: OI25_2230
PNU: Pnuc_1827
BPT: Bpet3016
ODI: ODI_R2116
VEI: Veis_4399
DAC: Daci_0605
CTES: O987_02360
JAG: GJA_1948
CFU: CFU_3581
LCH: Lcho_1753
TIN: Tint_0323
THI: THI_0359
MMB: Mmol_0910
MEH: M301_0992
MEP: MPQ_2726
DAR: Daro_0785
TCL: Tchl_0404
GEO: Geob_0648
PPD: Ppro_3331
DPI: BN4_12635
DBA: Dbac_1874
DOL: Dole_1087
SCL: sce6916
RPE: RPE_2672
MDI: METDI3576
MEX: Mext_2809
MCH: Mchl_3037
MPO: Mpop_3854
META: Y590_13555
BID: Bind_0441
HDN: Hden_1151
ALB: AEB_P2985
ACR: Acry_0103
TXI: TH3_07240
PUF: UFO1_2904
PFT: JBW_01759
PMT: PMT_1811
AMR: AM1_1237
MPK: VL20_2464
CYT: cce_2852
CALH: IJ00_20345
TTR: Tter_2822
PUV: PUV_15350
OTE: Oter_0461
PIR: VN12_00870(yrrB_1) VN12_15170
RUL: UC8_02840
GMR: GmarT_02750(yrrB_1)
GES: VT84_38485(yrrB_3)
IPA: Isop_0879
AGV: OJF2_07990(yrrB_1) OJF2_10470 OJF2_62140(yrrB_8)
KST: KSMBR1_3635(rfe_5)
BIP: Bint_0207
ABAC: LuPra_02590(yrrB_3)
CCH: Cag_0732
PPH: Ppha_0641
 » show all
Reference
PMID:9083068
  Authors
Lubas WA, Frank DW, Krause M, Hanover JA
  Title
O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats.
  Journal
J Biol Chem 272:9316-24 (1997)
DOI:10.1074/jbc.272.14.9316
  Sequence
[hsa:8473] [cel:CELE_K04G7.3]

KEGG   ORTHOLOGY: K18134
Entry
K18134                      KO                                     

Name
EOGT
Definition
EGF domain-specific O-GlcNAc transferase [EC:2.4.1.255]
Pathway
ko00514  Other types of O-glycan biosynthesis
Disease
H01413  Adams-Oliver syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    K18134  EOGT; EGF domain-specific O-GlcNAc transferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K18134  EOGT; EGF domain-specific O-GlcNAc transferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.255  protein O-GlcNAc transferase
     K18134  EOGT; EGF domain-specific O-GlcNAc transferase
Glycosyltransferases [BR:ko01003]
 O-Glycan biosynthesis
  O-linked GlcNAc type
   K18134  EOGT; EGF domain-specific O-GlcNAc transferase
Other DBs
RN: R09304 R09676
GO: 0097363
CAZy: GT61
Genes
HSA: 285203(EOGT)
PTR: 494220(EOGT)
PPS: 100970968(EOGT)
GGO: 101130943(EOGT)
PON: 100440288(EOGT)
NLE: 100597324(EOGT)
MCC: 696742(EOGT)
MCF: 102115709(EOGT)
CSAB: 103227871(EOGT)
RRO: 104677919(EOGT)
RBB: 108520117(EOGT)
CJC: 100390811(EOGT)
SBQ: 101048286(EOGT)
MMU: 101351(Eogt)
MCAL: 110295728(Eogt)
MPAH: 110316878(Eogt)
RNO: 494219(Eogt)
MUN: 110551653(Eogt)
CGE: 100757071(Eogt)
NGI: 103729142(Eogt)
HGL: 101715607(Eogt)
CCAN: 109691372(Eogt)
OCU: 100342123(EOGT)
TUP: 102499112(EOGT)
CFA: 494221(EOGT)
VVP: 112909151(EOGT)
AML: 100479105(EOGT)
UMR: 103674238(EOGT)
UAH: 113257067(EOGT)
ORO: 101370331(EOGT)
ELK: 111143973
FCA: 101089680(EOGT)
PTG: 102959921(EOGT)
PPAD: 109279033(EOGT)
AJU: 106975137(EOGT)
BTA: 508782(EOGT)
BOM: 102279900(EOGT)
BIU: 109576379(EOGT)
BBUB: 102414295(EOGT)
CHX: 102176741(EOGT)
OAS: 101117114(EOGT)
SSC: 100155485(EOGT)
CFR: 102521209(EOGT)
CDK: 105095255(EOGT)
BACU: 103018912(EOGT)
LVE: 103071794(EOGT)
OOR: 101276173(EOGT)
DLE: 111174202(EOGT)
PCAD: 102974565(EOGT)
ECB: 100053493(EOGT)
EPZ: 103550858(EOGT)
EAI: 106827921(EOGT)
MYB: 102247874(EOGT)
MYD: 102751826(EOGT)
MNA: 107530428(EOGT)
HAI: 109392531(EOGT)
DRO: 112301247(EOGT)
PALE: 102879009(EOGT)
RAY: 107497451(EOGT)
MJV: 108395819(EOGT)
LAV: 100671086(EOGT)
TMU: 101354162
MDO: 100618477(EOGT)
SHR: 100931735(EOGT)
PCW: 110222535(EOGT)
OAA: 100078373(EOGT)
GGA: 426961(EOGT)
MGP: 100550764(EOGT)
CJO: 107319994(EOGT)
NMEL: 110404631(EOGT)
APLA: 101796788(EOGT)
ACYG: 106035493(EOGT)
TGU: 100225538(EOGT)
LSR: 110482002(EOGT)
SCAN: 103817084(EOGT)
GFR: 102042181(EOGT)
FAB: 101809614(EOGT)
PHI: 102113990(EOGT)
PMAJ: 107210283(EOGT)
CCAE: 111934977(EOGT)
CCW: 104683359(EOGT)
ETL: 114063090(EOGT)
FPG: 101923329(EOGT)
FCH: 102050428(EOGT)
CLV: 102092951(EOGT)
EGZ: 104132663(EOGT)
NNI: 104016922(EOGT)
ACUN: 113484949(EOGT)
PADL: 103921788(EOGT)
AAM: 106494570(EOGT)
ASN: 102381905(EOGT)
AMJ: 102576718(EOGT)
PSS: 102448245(EOGT)
CMY: 102946700(EOGT)
CPIC: 101947597(EOGT)
ACS: 100554805(eogt)
PVT: 110083322(EOGT)
PBI: 103048321(EOGT)
PMUR: 107302642(EOGT)
TSR: 106553479(EOGT)
PMUA: 114591850(EOGT)
GJA: 107121813(EOGT)
XLA: 443983(eogt.L)
XTR: 780148(eogt)
NPR: 108786181(EOGT)
DRE: 798087(eogt)
SANH: 107696816(eogt)
IPU: 108254783(eogt)
PHYP: 113539733(eogt)
AMEX: 103044264(eogt)
EEE: 113580746(eogt)
TRU: 777950(eogt)
LCO: 104933151(eogt)
NCC: 104944985
MZE: 101484112(eogt)
ONL: 100707880(eogt)
OLA: 101170339(eogt)
XMA: 102236401(eogt)
XCO: 114136179(eogt)
PRET: 103465051(eogt)
CVG: 107091495(eogt)
NFU: 107385431(eogt)
KMR: 108244079(eogt)
ALIM: 106518517(eogt)
AOCE: 111588777(eogt)
CSEM: 103386183(eogt)
POV: 109629413(eogt)
LCF: 108885653(eogt)
SDU: 111221765(eogt)
SLAL: 111670901(eogt)
HCQ: 109509878(eogt)
BPEC: 110165803(eogt)
MALB: 109956143(eogt)
SALP: 111968556(eogt) 111970572
ELS: 105017304(eogt)
SFM: 108923320(eogt)
PKI: 111834588(eogt)
LCM: 102352761(EOGT)
CMK: 103179783(eogt)
RTP: 109933608(eogt) 109936141
CIN: 100176976 497241(aer61)
SPU: 100890388
APLC: 110989761
SKO: 100372242
DME: Dmel_CG9867(Eogt)
DER: 6542811
DSE: 6613092
DSI: Dsimw501_GD23152(Dsim_GD23152)
DAN: 6498314
DSR: 110184962
DPE: 6596522
DMN: 108163697
DWI: 6641782
DAZ: 108611850
DNV: 108649706
DHE: 111599377
DVI: 6627351
MDE: 101889542
LCQ: 111681076
AAG: 5569871
AME: 408434
BIM: 100743889
BTER: 100646555
CCAL: 108626919
SOC: 105201611
MPHA: 105841105
AEC: 105151364
ACEP: 105625209
PBAR: 105422886
VEM: 105569184
HST: 105182279
DQU: 106747334
CFO: 105250987
LHU: 105676455
PGC: 109853171
OBO: 105282081
PCF: 106787689
NVI: 100114611
CSOL: 105364338
MDL: 103568784
TCA: 655363
DPA: 109544122
ATD: 109604493
NVL: 108566587
BMOR: 101744474
BMAN: 114252908
PMAC: 106710742
PRAP: 110998674
HAW: 110375461
TNL: 113501220
PXY: 105387337
API: 100163033
DNX: 107166738
AGS: 114130515
RMD: 113556679
BTAB: 109039328
CLEC: 106670611
ZNE: 110828855
FCD: 110847070
PVM: 113808616
TUT: 107360031
DPTE: 113794030
CSCU: 111639868
CEL: CELE_H12D21.10(H12D21.10)
TSP: Tsp_08546
PCAN: 112572924
CRG: 105335741
MYI: 110461705
OBI: 106876274
PDAM: 113681886
DGT: 114533646
CIT: 107177613
DZI: 111317598
GMX: 100800935
GSJ: 114370907
VRA: 106755281
VAR: 108334938
CCAJ: 109803024
CAM: 101493470
PPER: 18789169
PAVI: 110751416
MDM: 103416501
HBR: 110668352
VVI: 104877597
NSY: 104238111
INI: 109166387
LSV: 111889675
NNU: 104594063
MAW: MAC_09096
MAJ: MAA_03264
CMT: CCM_09057
SMIN: v1.2.021970.t1(symbB.v1.2.021970.t1)
 » show all
Reference
  Authors
Sakaidani Y, Nomura T, Matsuura A, Ito M, Suzuki E, Murakami K, Nadano D, Matsuda T, Furukawa K, Okajima T
  Title
O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions.
  Journal
Nat Commun 2:583 (2011)
DOI:10.1038/ncomms1591
  Sequence

KEGG   ENZYME: 2.4.1.255
Entry
EC 2.4.1.255                Enzyme                                 

Name
protein O-GlcNAc transferase;
O-GlcNAc transferase;
OGTase;
O-linked N-acetylglucosaminyltransferase;
uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase;
protein O-linked beta-N-acetylglucosamine transferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-N-alpha-acetyl-D-glucosamine:[protein]-3-O-N-acetyl-beta-D-glucosaminyl transferase
Reaction(IUBMB)
(1) UDP-N-acetyl-alpha-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine [RN:R09304 R09676];
(2) UDP-N-acetyl-alpha-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine [RN:R09677]
Reaction(KEGG)
R09304(G) R09676 R09677
Substrate
UDP-N-acetyl-alpha-D-glucosamine [CPD:C00043];
[protein]-L-serine [CPD:C02189];
[protein]-L-threonine [CPD:C19803]
Product
UDP [CPD:C00015];
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine [CPD:C19802];
[protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine [CPD:C19804]
Comment
Within higher eukaryotes post-translational modification of protein serines/threonines with N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation. EC 2.4.1.255 (protein O-GlcNAc transferase) transfers GlcNAc onto substrate proteins and EC 3.2.1.169 (protein O-GlcNAcase) cleaves GlcNAc from the modified proteins.
History
EC 2.4.1.255 created 2011
Pathway
ec00514  Other types of O-glycan biosynthesis
Orthology
K09667  protein O-GlcNAc transferase
K18134  EGF domain-specific O-GlcNAc transferase
Genes
HSA: 285203(EOGT) 8473(OGT)
PTR: 465702(OGT) 494220(EOGT)
PPS: 100970968(EOGT) 100989146(OGT)
GGO: 101130943(EOGT) 101140533(OGT)
PON: 100440288(EOGT)
NLE: 100591966(OGT) 100597324(EOGT)
MCC: 696742(EOGT) 698268(OGT)
MCF: 101866582(OGT) 102115709(EOGT)
CSAB: 103227871(EOGT) 103232164(OGT)
RRO: 104664903(OGT) 104677919(EOGT)
RBB: 108520117(EOGT) 108527587(OGT)
CJC: 100386886(OGT) 100390811(EOGT)
SBQ: 101045971(OGT) 101048286(EOGT)
MMU: 101351(Eogt) 108155(Ogt)
MCAL: 110286164(Ogt) 110295728(Eogt)
MPAH: 110313595(Ogt) 110316878(Eogt)
RNO: 26295(Ogt) 494219(Eogt)
MUN: 110540923(Ogt) 110551653(Eogt)
CGE: 100757071(Eogt) 100768670(Ogt)
NGI: 103729142(Eogt) 103751946(Ogt)
HGL: 101710902 101715607(Eogt) 101721730(Ogt)
CCAN: 109691372(Eogt) 109699231(Ogt)
OCU: 100342123(EOGT) 100354727(OGT)
TUP: 102479359(OGT) 102499112(EOGT)
CFA: 480955(OGT) 494221(EOGT)
VVP: 112907620(OGT) 112909151(EOGT)
AML: 100475282(OGT) 100479105(EOGT)
UMR: 103674238(EOGT) 103682584(OGT)
UAH: 113245624(OGT) 113257067(EOGT)
ORO: 101369290(OGT) 101370331(EOGT)
FCA: 101089680(EOGT) 101094162(OGT)
PTG: 102959921(EOGT) 102964072(OGT)
PPAD: 109254620(OGT) 109279033(EOGT)
AJU: 106975137(EOGT) 106982362(OGT)
BTA: 508782(EOGT) 532053(OGT)
BOM: 102279900(EOGT) 102286677(OGT)
BIU: 109555132 109576379(EOGT)
BBUB: 102397041(OGT) 102414295(EOGT)
CHX: 102176741(EOGT) 102187305(OGT)
OAS: 101106996(OGT) 101117114(EOGT)
SSC: 100155485(EOGT) 664652(OGT)
CFR: 102516733(OGT) 102521209(EOGT)
CDK: 105087990(OGT) 105095255(EOGT)
BACU: 103018912(EOGT) 103019745 103020800(OGT)
LVE: 103071794(EOGT) 103073601(OGT)
OOR: 101276173(EOGT) 101282914(OGT)
DLE: 111167771(OGT) 111174202(EOGT)
ECB: 100053493(EOGT) 100056148(OGT)
EPZ: 103542615(OGT) 103550858(EOGT)
EAI: 106827921(EOGT) 106828870(OGT)
MYB: 102245549(OGT) 102247874(EOGT)
MYD: 102751826(EOGT) 102773180(OGT)
MNA: 107530428(EOGT) 107532885(OGT)
HAI: 109385597(OGT) 109392531(EOGT)
DRO: 112300108(OGT) 112301247(EOGT)
PALE: 102879009(EOGT) 102890872(OGT)
RAY: 107497451(EOGT) 107513897(OGT)
MJV: 108395819(EOGT) 108396625(OGT)
LAV: 100662852(OGT) 100671086(EOGT)
MDO: 100011073(OGT) 100618477(EOGT)
SHR: 100929019(OGT) 100931735(EOGT)
PCW: 110201103(OGT) 110222535(EOGT)
OAA: 100078373(EOGT) 103169766(OGT)
GGA: 422203(OGT) 426961(EOGT)
MGP: 100538830(OGT) 100550764(EOGT)
CJO: 107312490(OGT) 107319994(EOGT)
NMEL: 110403357(OGT) 110404631(EOGT)
APLA: 101796788(EOGT) 101799851(OGT)
ACYG: 106035493(EOGT) 106037709(OGT)
TGU: 100224237(OGT) 100225538(EOGT)
LSR: 110472655(OGT) 110482002(EOGT)
SCAN: 103817084(EOGT) 103824224(OGT)
GFR: 102042181(EOGT) 102044727(OGT)
FAB: 101808611(OGT) 101809614(EOGT)
PHI: 102112943(OGT) 102113990(EOGT)
PMAJ: 107203795(OGT) 107210283(EOGT)
CCAE: 111929384(OGT) 111934977(EOGT)
CCW: 104683359(EOGT) 104691638(OGT)
ETL: 114063090(EOGT) 114066210(OGT)
FPG: 101915918(OGT) 101923329(EOGT)
FCH: 102050428(EOGT) 102052264(OGT)
CLV: 102092523(OGT) 102092951(EOGT)
EGZ: 104124274(OGT) 104132663(EOGT)
NNI: 104012908(OGT) 104016922(EOGT)
ACUN: 113479886(OGT) 113484949(EOGT)
PADL: 103921788(EOGT) 103923339(OGT)
AAM: 106482679(OGT) 106494570(EOGT)
ASN: 102381905(EOGT) 102387350(OGT)
AMJ: 102575029(OGT) 102576718(EOGT)
PSS: 102445994(OGT) 102448245(EOGT)
CMY: 102932353 102946700(EOGT)
CPIC: 101937402(OGT) 101947597(EOGT)
ACS: 100554805(eogt) 100561277(ogt)
PVT: 110080200(OGT) 110083322(EOGT)
PBI: 103048321(EOGT) 103059316(OGT)
PMUR: 107302642(EOGT) 107303237(OGT)
TSR: 106552555(OGT) 106553479(EOGT)
PMUA: 114588797(OGT) 114591850(EOGT)
GJA: 107108561(OGT) 107121813(EOGT)
XLA: 443983(eogt.L) 447694(ogt.L)
XTR: 553157(ogt) 780148(eogt)
NPR: 108786181(EOGT) 108802573(OGT)
DRE: 337685(ogt.1) 652952(ogt.2) 798087(eogt)
SANH: 107663079(ogt) 107688794 107696816(eogt)
IPU: 108254783(eogt) 108268666(ogt)
PHYP: 113539733(eogt) 113542871(ogt)
AMEX: 103028765(ogt) 103044264(eogt)
EEE: 113576512(ogt) 113580746(eogt)
TRU: 101076057(ogt) 777950(eogt)
LCO: 104923189(ogt) 104933151(eogt)
NCC: 104944985 104952211(ogt)
MZE: 101479094(ogt) 101484112(eogt)
ONL: 100697871(ogt) 100707880(eogt)
OLA: 101164571(ogt) 101170339(eogt)
XMA: 102227742(ogt) 102236401(eogt)
XCO: 114136179(eogt) 114139527(ogt)
PRET: 103465051(eogt) 103471170(ogt)
CVG: 107089044(ogt) 107091495(eogt)
NFU: 107385431(eogt) 107395869(ogt)
KMR: 108240572(ogt) 108244079(eogt)
ALIM: 106515959(ogt) 106518517(eogt)
AOCE: 111565562(ogt) 111588777(eogt)
CSEM: 103386183(eogt) 103391144(ogt)
POV: 109626074(ogt) 109629413(eogt)
LCF: 108882891(ogt) 108885653(eogt)
SDU: 111221765(eogt) 111226555(ogt)
SLAL: 111652072(ogt) 111670901(eogt)
HCQ: 109509878(eogt) 109515817(ogt)
BPEC: 110163678(ogt) 110165803(eogt)
MALB: 109956143(eogt) 109968379(ogt)
SALP: 111968556(eogt) 111970572 112069184(ogt)
ELS: 105017304(eogt) 105025795(ogt)
PKI: 111834588(eogt) 111843708(ogt)
LCM: 102352761(EOGT) 102361281(OGT)
CMK: 103179783(eogt) 103189357(ogt)
RTP: 109933608(eogt) 109935524(ogt) 109936141
DME: Dmel_CG10392(sxc) Dmel_CG9867(Eogt)
DSI: Dsimw501_GD17889(Dsim_GD17889) Dsimw501_GD23152(Dsim_GD23152) Dsimw501_GD28381(Dsim_GD28381)
NVI: 100114611 100116809(Ogt)
CEL: CELE_H12D21.10(H12D21.10) CELE_K04G7.3(ogt-1)
CBR: CBG16605(Cbr-ogt-1)
BMY: Bm1_01735
SHX: MS3_06840
EGL: EGR_08361
HMG: 100201589
ATH: AT3G04240(SEC) AT3G11540(SPY)
LJA: Lj5g3v0803050.1(Lj5g3v0803050.1) Lj5g3v1303350.1(Lj5g3v1303350.1) Lj5g3v1303350.2(Lj5g3v1303350.2)
DOSA: Os02t0489550-00(Os02g0489550) Os08t0559300-01(Os08g0559300)
ATS: 109763129(LOC109763129) 109782465(LOC109782465)
ZMA: 100191509(pco141552) 100381672(cl27878_1(278))
CRE: CHLREDRAFT_117813(OGT1)
MNG: MNEG_0970
MAW: MAC_09096
MAJ: MAA_03264
CMT: CCM_09057
DDI: DDB_G0285263(spyA)
DFA: DFA_05779(spyA)
CPV: cgd1_1300
SMIN: v1.2.002533.t1(symbB.v1.2.002533.t1) v1.2.015572.t2(symbB.v1.2.015572.t2) v1.2.021970.t1(symbB.v1.2.021970.t1) v1.2.023338.t1(symbB.v1.2.023338.t1)
DKO: I596_1643
MCA: MCA1509
AEH: Mlg_0699
CSA: Csal_1986
APAC: S7S_17190
SLIM: SCL_1574
SVA: SVA_1487
SALN: SALB1_1846
TBN: TBH_C0586
RSY: RSUY_33650(yrrB_2)
BGO: BM43_4753
BFN: OI25_2230
PNU: Pnuc_1827
BPT: Bpet3016
ODI: ODI_R2116
VEI: Veis_4399
DAC: Daci_0605
CTES: O987_02360
JAG: GJA_1948
CFU: CFU_3581
LCH: Lcho_1753
TIN: Tint_0323
THI: THI_0359
MMB: Mmol_0910
MEH: M301_0992
MEP: MPQ_2726
DAR: Daro_0785
TCL: Tchl_0404
GEO: Geob_0648
PPD: Ppro_3331
DPI: BN4_12635
DBA: Dbac_1874
DOL: Dole_1087
SCL: sce6916
RPE: RPE_2672
MDI: METDI3576
MEX: Mext_2809
MCH: Mchl_3037
MPO: Mpop_3854
META: Y590_13555
BID: Bind_0441
HDN: Hden_1151
ALB: AEB_P2985
ACR: Acry_0103
TXI: TH3_07240
PUF: UFO1_2904
PFT: JBW_01759
PMT: PMT_1811
AMR: AM1_1237
MPK: VL20_2464
CYT: cce_2852
CALH: IJ00_20345
TTR: Tter_2822
PUV: PUV_15350
OTE: Oter_0461
PIR: VN12_00870(yrrB_1) VN12_15170
RUL: UC8_02840
GMR: GmarT_02750(yrrB_1)
GES: VT84_38485(yrrB_3)
IPA: Isop_0879
AGV: OJF2_07990(yrrB_1) OJF2_10470 OJF2_62140(yrrB_8)
KST: KSMBR1_3635(rfe_5)
BIP: Bint_0207
ABAC: LuPra_02590(yrrB_3)
CCH: Cag_0732
PPH: Ppha_0641
 » show all
Reference
1  [PMID:18948359]
  Authors
Banerjee S, Robbins PW, Samuelson J
  Title
Molecular characterization of nucleocytosolic O-GlcNAc transferases of Giardia lamblia and Cryptosporidium parvum.
  Journal
Glycobiology 19:331-6 (2009)
DOI:10.1093/glycob/cwn107
  Sequence
Reference
2  [PMID:18818698]
  Authors
Clarke AJ, Hurtado-Guerrero R, Pathak S, Schuttelkopf AW, Borodkin V, Shepherd SM, Ibrahim AF, van Aalten DM
  Title
Structural insights into mechanism and specificity of O-GlcNAc transferase.
  Journal
EMBO J 27:2780-8 (2008)
DOI:10.1038/emboj.2008.186
Reference
3  [PMID:16541109]
  Authors
Rao FV, Dorfmueller HC, Villa F, Allwood M, Eggleston IM, van Aalten DM
  Title
Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis.
  Journal
EMBO J 25:1569-78 (2006)
DOI:10.1038/sj.emboj.7601026
Reference
4  [PMID:1533623]
  Authors
Haltiwanger RS, Blomberg MA, Hart GW
  Title
Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase.
  Journal
J Biol Chem 267:9005-13 (1992)
Reference
5  [PMID:9083068]
  Authors
Lubas WA, Frank DW, Krause M, Hanover JA
  Title
O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats.
  Journal
J Biol Chem 272:9316-24 (1997)
DOI:10.1074/jbc.272.14.9316
  Sequence
[cel:CELE_K04G7.3] [hsa:8473]
Reference
6  [PMID:21240259]
  Authors
Lazarus MB, Nam Y, Jiang J, Sliz P, Walker S
  Title
Structure of human O-GlcNAc transferase and its complex with a peptide substrate.
  Journal
Nature 469:564-7 (2011)
DOI:10.1038/nature09638
  Sequence
[hsa:8473]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.255
IUBMB Enzyme Nomenclature: 2.4.1.255
ExPASy - ENZYME nomenclature database: 2.4.1.255
BRENDA, the Enzyme Database: 2.4.1.255

KEGG   REACTION: R09304
Entry
R09304                      Reaction                               

Definition
UDP-N-acetyl-D-glucosamine + [Protein]-L-serine <=> UDP + G12573
Equation
Remark
Same as: R09676
Enzyme
Pathway
rn00514  Other types of O-glycan biosynthesis
Orthology
K09667  protein O-GlcNAc transferase [EC:2.4.1.255]
K18134  EGF domain-specific O-GlcNAc transferase [EC:2.4.1.255]

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