KEGG   ORTHOLOGY: K09831Help
Entry
K09831                      KO                                     

Name
ERG5, CYP61A
Definition
sterol 22-desaturase [EC:1.14.19.41]
Pathway
ko00100  Steroid biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00102  Ergocalciferol biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K09831  ERG5, CYP61A; sterol 22-desaturase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K09831  ERG5, CYP61A; sterol 22-desaturase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.41  sterol 22-desaturase
     K09831  ERG5, CYP61A; sterol 22-desaturase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP61 family
   K09831  ERG5, CYP61A; sterol 22-desaturase
BRITE hierarchy
Other DBs
RN: R07506
COG: COG2124
GO: 0000249
Genes
QSU: 112004265 112037010 112037011
SCE: YMR015C(ERG5)
AGO: AGOS_ABR053C
KLA: KLLA0_D11242g
KMX: KLMA_60417(cyp524A1)
LTH: KLTH0D07832g
VPO: Kpol_1056p10
ZRO: ZYRO0E06204g
CGR: CAGL0M07656g
NCS: NCAS_0A12700(NCAS0A12700)
NDI: NDAI_0B01560(NDAI0B01560)
TPF: TPHA_0I02420(TPHA0I02420)
TBL: TBLA_0H02650(TBLA0H02650)
TDL: TDEL_0B06510(TDEL0B06510)
KAF: KAFR_0A02110(KAFR0A02110)
PIC: PICST_73043(ERG5)
SPAA: SPAPADRAFT_63544(ERG5)
CAL: CAALFM_C702840CA(ERG5)
SLB: AWJ20_75(ERG5)
NCR: NCU05278
NTE: NEUTE1DRAFT116692(NEUTE1DRAFT_116692)
MGR: MGG_06047
SSCK: SPSK_00476
MAW: MAC_08636
MAJ: MAA_01109
CMT: CCM_02962
BFU: BCIN_07g01120(Bcerg5)
MBE: MBM_06688
ANI: AN4042.2
ANG: ANI_1_350014(An01g02810) ANI_1_446094(An11g03230)
PBL: PAAG_11073(PAAG_00230)
ABE: ARB_03814
TVE: TRV_05093
PTE: PTT_19871
ZTR: MYCGRDRAFT_55438(CYP-70)
SPO: SPAC19A8.04(erg5)
CNE: CNF03720
CNB: CNBF1100
HIR: HETIRDRAFT_141009(cpm111)
LBC: LACBIDRAFT_187166(ERG5)
ABP: AGABI1DRAFT66440(AGABI1DRAFT_66440)
ABV: AGABI2DRAFT189837(AGABI2DRAFT_189837)
MGL: MGL_0310
MRT: MRET_0994
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8635732
  Authors
Skaggs BA, Alexander JF, Pierson CA, Schweitzer KS, Chun KT, Koegel C, Barbuch R, Bard M
  Title
Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis.
  Journal
Gene 169:105-9 (1996)
DOI:10.1016/0378-1119(95)00770-9
  Sequence
[sce:YMR015C]

KEGG   REACTION: R07506Help
Entry
R07506                      Reaction                               

Name
ergosta-5,7,24(28)-trien-3beta-ol,NADPH:oxygen oxidoreductase (22,23-dehydrogenating)
Definition
5,7,24(28)-Ergostatrienol + NADPH + H+ + Oxygen <=> Ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O
Equation
Reaction class
RC00001  C00005_C00006
RC01970  C05440_C15778
Enzyme
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00102  Ergocalciferol biosynthesis
Orthology
K09831  sterol 22-desaturase [EC:1.14.19.41]
Other DBs
RHEA: 33470

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