KEGG ORTHOLOGY: K10151

ORTHOLOGY: K10151

Entry

K10151                      KO

Symbol

CCND2

Name

G1/S-specific cyclin-D2

Pathway

map04068

FoxO signaling pathway

map04110

Cell cycle

map04115

p53 signaling pathway

map04151

PI3K-Akt signaling pathway

map04218

Cellular senescence

map04310

Wnt signaling pathway

map04340

Hedgehog signaling pathway

map04390

Hippo signaling pathway

map04510

Focal adhesion

map04630

JAK-STAT signaling pathway

map04917

Prolactin signaling pathway

map05162

Measles

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05169

Epstein-Barr virus infection

map05200

Pathways in cancer

map05202

Transcriptional misregulation in cancer

map05203

Viral carcinogenesis

map05206

MicroRNAs in cancer

Disease

H00023

Testicular cancer

H01885

Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04340 Hedgehog signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04390 Hippo signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04630 JAK-STAT signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04068 FoxO signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04151 PI3K-Akt signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K10151  CCND2; G1/S-specific cyclin-D2
   04115 p53 signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
   04218 Cellular senescence
    K10151  CCND2; G1/S-specific cyclin-D2
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10151  CCND2; G1/S-specific cyclin-D2
09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K10151  CCND2; G1/S-specific cyclin-D2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05202 Transcriptional misregulation in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05206 MicroRNAs in cancer
    K10151  CCND2; G1/S-specific cyclin-D2
   05203 Viral carcinogenesis
    K10151  CCND2; G1/S-specific cyclin-D2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05162 Measles
    K10151  CCND2; G1/S-specific cyclin-D2
   05169 Epstein-Barr virus infection
    K10151  CCND2; G1/S-specific cyclin-D2
   05165 Human papillomavirus infection
    K10151  CCND2; G1/S-specific cyclin-D2

Genes

HSA:	894(CCND2)

PTR:	747123(CCND2)

PPS:	100990850(CCND2)

GGO:	101139749(CCND2)

PON:	100457978(CCND2)

PPYG:

129010881(CCND2)

NLE:	100585770(CCND2)

HMH:	116472548(CCND2)

SSYN:

129483515(CCND2)

MCC:	710379(CCND2)

MCF:	102119572(CCND2)

MTHB:

126931745

MNI:	105484147(CCND2)

CSAB:

103218410(CCND2)

CATY:

105582988(CCND2)

PANU:

101004371(CCND2)

TGE:	112634321(CCND2)

MLEU:

105551132(CCND2)

RRO:	104658979(CCND2)

RBB:	108536489(CCND2)

TFN:	117090678(CCND2)

PTEH:

111535839(CCND2)

CANG:

105503930(CCND2)

CJC:	100390172(CCND2)

SBQ:	101049141(CCND2)

CIMI:

108316314(CCND2)

ANAN:

105719719(CCND2)

CSYR:

103250109(CCND2)

MMUR:

105881459(CCND2)

LCAT:

123640152(CCND2)

PCOQ:

105822622(CCND2)

OGA:	100962188(CCND2)

MMU:	12444(Ccnd2)

MCAL:

110296334(Ccnd2)

MPAH:

110315929(Ccnd2)

RNO:	64033(Ccnd2)

MCOC:

116099629(Ccnd2)

ANU:	117714829(Ccnd2)

MUN:	110548628(Ccnd2)

CGE:	100771544(Ccnd2)

MAUA:

101835885(Ccnd2)

PROB:

127213021(Ccnd2)

PLEU:

114701440(Ccnd2)

MORG:

121435389(Ccnd2)

MFOT:

126488490

AAMP:

119808297(Ccnd2)

NGI:	103727547(Ccnd2)

HGL:	101721480(Ccnd2)

CPOC:

100730596(Ccnd2)

CCAN:

109688460 109688461

DORD:

105991130(Ccnd2)

DSP:

122102140

NCAR:

124982598

MMMA:

107154990(Ccnd2)

OCU:

100009036

OPI:	101528096(CCND2)

TUP:	102479902(CCND2)

GVR:	103603964(CCND2)

CFA:	611782(CCND2)

CLUD:

112669048(CCND2)

VVP:	112917379(CCND2)

VLG:	121479990(CCND2)

NPO:	129503406(CCND2)

AML:	100471517(CCND2)

UMR:	103675743(CCND2)

UAH:	113258003(CCND2)

UAR:	123781570(CCND2)

ELK:

111159766

LLV:

125105988

MPUF:

101684525(CCND2)

MNP:	132019951(CCND2)

MLK:	131838412(CCND2)

NVS:	122892551(CCND2)

ORO:	101363193(CCND2)

EJU:	114222473(CCND2)

ZCA:	113921399(CCND2)

MLX:	118025766(CCND2)

NSU:	110580853(CCND2)

LWW:	102747548(CCND2)

FCA:	101090950(CCND2)

PYU:	121021950(CCND2)

PCOO:

112867915(CCND2)

PBG:	122472689(CCND2)

PVIV:

125169721(CCND2)

LRUF:

124501054

PTG:	102970259(CCND2)

PPAD:

109276198(CCND2)

PUC:	125917183 125918030

AJU:

106965383

HHV:	120247732(CCND2)

BTA:	615414(CCND2)

BOM:	102272576(CCND2)

BIU:	109559745(CCND2)

BBUB:

102410004(CCND2)

BBIS:

104992217(CCND2)

CHX:	102180657(CCND2)

OAS:	100147799(CCND2)

BTAX:

128048410(CCND2)

ODA:	120857878(CCND2)

CCAD:

122424006(CCND2)

MBEZ:

129536390(CCND2)

SSC:	397162(CCND2)

CFR:	116661359(CCND2)

CBAI:

105076506(CCND2)

CDK:	105091327(CCND2)

VPC:	102544159(CCND2)

BACU:

103002964(CCND2)

BMUS:

118901914(CCND2)

LVE:	103077970(CCND2)

OOR:	101274693(CCND2)

DLE:	111176638(CCND2)

PCAD:

102981679(CCND2)

PSIU:

116760293(CCND2)

NASI:

112391672(CCND2)

ECB:	100051150(CCND2)

EPZ:	103567717(CCND2)

EAI:	106831500(CCND2)

MYB:	102254218(CCND2)

MYD:	102755701(CCND2)

MMYO:

118650032(CCND2)

MLF:	102422703(CCND2)

MDT:	132228041(CCND2)

PKL:	118728810(CCND2)

EFUS:

103288032(CCND2)

MNA:	107538904(CCND2)

DRO:	112312821(CCND2)

SHON:

118999952(CCND2)

AJM:	119054859(CCND2)

PDIC:

114514087(CCND2)

PHAS:

123813418(CCND2)

MMF:	118624468(CCND2)

PPAM:

129074231(CCND2)

HAI:	109392488(CCND2)

RFQ:	117028515(CCND2)

PALE:

102892640(CCND2)

PGIG:

120607308(CCND2)

PVP:	105293261(CCND2)

RAY:	107513450(CCND2)

MJV:	108403976(CCND2)

TOD:	119247816(CCND2)

SARA:

101541876(CCND2)

SETR:

126006674(CCND2)

LAV:	100668070(CCND2)

TMU:

101351510

ETF:	101657079(CCND2)

DNM:	101443494(CCND2)

MDO:	100016259(CCND2)

GAS:	123250729(CCND2)

SHR:	100915359(CCND2)

AFZ:

127539247

PCW:	110218698(CCND2)

TVP:	118851637(CCND2)

OAA:	100088940(CCND2)

GGA:	374047(CCND2)

PCOC:

116237231(CCND2)

MGP:

104909362

CJO:	107318017(CCND2)

TPAI:

128084476(CCND2)

LMUT:

125688187(CCND2)

NMEL:

110390646(CCND2)

APLA:

101802600(CCND2)

ACYG:

106046294(CCND2)

CATA:

118247742(CCND2)

AFUL:

116494310(CCND2)

TGU:	100224096(CCND2)

LSR:	110479030(CCND2)

SCAN:

103819603(CCND2)

PMOA:

120501661(CCND2)

OTC:	121332924(CCND2)

PRUF:

121364327(CCND2)

GFR:	102034688(CCND2)

FAB:	101818224(CCND2)

OMA:	130266305(CCND2)

PHI:	102114518(CCND2)

PMAJ:

107204709(CCND2)

CCAE:

111930045(CCND2)

CCW:	104696177(CCND2)

CBRC:

103623342(CCND2)

ETL:	114067087(CCND2)

ZAB:	102075450(CCND2)

ZLE:	135441402(CCND2)

ACHL:

103801578(CCND2)

SVG:	106849378(CCND2)

MMEA:

130581573(CCND2)

HRT:	120752269(CCND2)

SATI:

136361634(CCND2)

FPG:	101920354(CCND2)

FCH:	102053549(CCND2)

NNT:	104410574(CCND2)

SHAB:

115605095(CCND2)

TALA:

104363998(CCND2)

ACHC:

115352414(CCND2)

HALD:

104312345(CCND2)

HLE:	104836645(CCND2)

AGEN:

126047911

GCL:

127016274

CSTI:

104561923

LDI:	104341678(CCND2)

DPUB:

104301122(CCND2)

AVIT:

104275342(CCND2)

EGZ:	104124210(CCND2)

NNI:	104021822(CCND2)

PCRI:

104031418(CCND2)

PCAO:

104047027(CCND2)

PADL:

103917223(CCND2)

AFOR:

103906574(CCND2)

GSTE:

104259895(CCND2)

CLV:	102093196(CCND2)

PGUU:

104469033

PLET:

104616874

CMAC:

104475814(CCND2)

CUCA:

104066622(CCND2)

BREG:

104631472(CCND2)

OHA:	104333010(CCND2)

ACAR:

104524507(CCND2)

CPEA:

104397228(CCND2)

CVF:	104294573(CCND2)

RTD:	128916624(CCND2)

AAM:	106489562(CCND2)

AROW:

112971495(CCND2)

NPD:	112953186(CCND2)

TGT:	104575218(CCND2)

DNE:	112986809(CCND2)

SCAM:

104144405(CCND2)

AMJ:	102564576(CCND2)

CPOO:

109316274(CCND2)

GGN:	109296569(CCND2)

PSS:	102462674(CCND2)

CMY:	102931445(CCND2)

CCAY:

125623801(CCND2)

DCC:	119859464(CCND2)

TST:	117884539(CCND2)

CABI:

116820266(CCND2)

MRV:	120383598(CCND2)

HCG:	128326250(CCND2)

GJA:	107110411(CCND2)

STOW:

125443877(CCND2)

EMC:	129343928(CCND2)

XLA:	373667(ccnd2.L) 734882(ccnd2.S)

XTR:	100038071(ccnd2)

NPR:	108788361(CCND2)

RTEM:

120932645(CCND2)

BBUF:

121007410(CCND2)

BGAR:

122928449(CCND2)

MUO:	115477354(CCND2)

GSH:	117364116(CCND2)

DRE:	565038(ccnd2b) 799608(ccnd2a)

SRX:	107707471 107710106 107725932 107729433 107732799 107732861

SANH:

107656417 107658897 107679598 107680849 107686624 107687630

SGH:	107551158 107563982 107572660 107575166 107579638 107583977

CCAR:

109049498 109050655 109075813

CAUA:

113041650 113043081 113043120 113047643 113048536 113059945 113066870

CGIB:

127947336 127956853 127978113 128014237

PTET:

122331218(ccnd2a) 122343391(ccnd2b)

LROH:

127156478(ccnd2a) 127164391(ccnd2b)

OMC:	131534119(ccnd2a) 131539081(ccnd2b)

PPRM:

120459029(ccnd2a) 120476639(ccnd2b) 120490241(ccndx)

RKG:	130069581(ccnd2b) 130085288(ccnd2a)

MAMB:

125244649(ccnd2b) 125246743(ccnd2a) 125276432(ccndx)

CIDE:

127506694 127510934

CERY:

137015465(ccnd2a) 137023774(ccnd2b)

MASI:

127435055 127435552 127436727 127437822

TROS:

130547593(ccnd2b) 130552232(ccnd2a)

TDW:	130413910(ccnd2a) 130420999(ccnd2b)

MANU:

129432438(ccnd2b) 129433224(ccnd2a)

IPU:	100528326(ccnd2a) 108279704(ccnd2b)

IFU:	128611710(ccnd2a) 128623310(ccnd2b)

PHYP:

113531710 113546664

SMEO:

124385932(ccnd2a) 124400777(ccnd2b)

TFD:	113635832(ccnd2a) 113647407(ccnd2b)

TVC:	132855556(ccnd2a) 132859211(ccnd2b)

TRN:	134319538(ccnd2a)

AMEX:

103031397(ccnd2a) 125799128(ccnd2b)

CMAO:

118806699(ccnd2a) 118812280(ccnd2b)

EEE:	113568595 113578084 113584974(ccnd2)

CHAR:

105896745(ccnd2b) 105897673(ccndx)

TRU:	101066871 101073562 101080220 115249879

TFS:	130515110(ccndx) 130519149 130536644

TNG:	GSTEN00016773G001 GSTEN00021540G001 GSTEN00027337G001

LCO:	104922121 104926717 104939073

NCC:	104942288 104950090(ccnd2) 104954387

TBEN:

117484991 117491872(ccnd2a) 117493088(ccndx)

CGOB:

115009437 115011756 115012676 115028528

PGEO:

117447816(ccnd2a) 117451689(ccndx) 117468457

GACU:

117542821(ccnd2a) 117548459(ccndx) 117559178

EMAC:

134877473(ccndx) 134877636(ccnd2a) 134879343

ELY:	117249418 117261646(ccnd2a) 117268238(ccndx)

EFO:	125879559(ccndx) 125882679 125886786(ccnd2a)

PLEP:

121949734(ccnd2a) 121957267(ccndx) 121961335

SLUC:

116053011(ccnd2a) 116060121 116063945(ccndx)

ECRA:

117938769 117948450(ccnd2a) 117957594(ccndx)

ESP:	116673298(ccnd2) 116703090

PFLV:

114550465 114560206(ccnd2) 114568885

GAT:	120808903(ccnd2a) 120812517 120817973 120827676(ccndx)

PPUG:

119196050(ccnd2a) 119210383 119220523(ccndx)

AFB:	129098265(ccndx) 129107686(ccnd2a) 129112322

CLUM:

117726348(ccnd2b) 117732096(ccnd2a) 117734722(ccndx)

PSWI:

130189054(ccndx) 130195190(ccnd2a) 130200639

MSAM:

119894029(ccnd2a) 119908399(ccndx) 119918426(ccnd2b)

SCHU:

122868879(ccndx) 122871393 122874759(ccnd2a)

CUD:	121505712 121515215(ccnd2a) 121529580(ccndx)

ALAT:

119013794(ccndx) 119023886(ccnd2a) 119032712

MZE:	101470118 101472403 101479984

ONL:	100698323 100707642 100712090

OAU:	116328674(ccndx) 116334728(ccnd2b) 116336265(ccnd2a)

OLA:	101163574 101174910 101175697

OML:	112146031(ccndx) 112152245(ccnd2a) 112154304

CSAI:

133422574(ccndx) 133424308 133424530 133443949(ccnd2a)

XMA:	102220824 102225733 102230338

XCO:	114152343 114160373 114160881

XHE:	116708600 116735422 116737028

PRET:

103459164 103466812 103469079

PFOR:

103129392 103144944 103155804

PLAI:

106936725 106953382 106956175 106965248

PMEI:

106910011 106921165 106926112(ccnd2)

GAF:	122822608(ccndx) 122826211(ccnd2b) 122835109(ccnd2a)

PPRL:

129356220 129356819 129360033 129373811(ccndx)

CVG:	107084303 107085698 107096865

CTUL:

119789178(ccnd2a) 119789997(ccndx) 119793178(ccnd2b)

GMU:	124863462 124864841 124878098(ccnd2a) 124883234(ccnd2b)

NFU:	107378596 107386279(ccnd2) 107389327

KMR:	108233174 108237544(ccnd2a) 108237745(ccndx)

ALIM:

106514815(ccnd2) 106524814 106535296

NWH:	119416197(ccnd2a) 119421328(ccndx) 119428509(ccnd2b)

AOCE:

111572740 111580353 111584035(ccnd2)

MCEP:

124998171(ccndx) 125000184 125014371(ccnd2a)

CSEM:

103379657 103382708(ccnd2) 103392544

POV:	109623974 109632688

SSEN:

122766831 122767234 122775413 122785616(ccndx)

HHIP:

117757192 117763749(ccnd2a) 117766356(ccndx)

HSP:	118101630 118110057(ccnd2a) 118123678(ccndx)

PPLT:

128428869 128444846(ccnd2a) 128458036(ccndx)

SMAU:

118288503 118288636(ccndx) 118315746(ccnd2a)

LCF:	108880592 108886219 108901859(ccnd2a)

SDU:	111217717 111224908 111225171

SLAL:

111660040 111660519 111666072

XGL:	120784119(ccndx) 120792847(ccnd2a) 120802400

HCQ:	109526797(ccnd2) 109527710 109530113

SSCV:

125970452 125984074 125992155

SBIA:

133493683 133502285(ccnd2a) 133514928(ccndx)

PEE:	133396915 133402502(ccnd2a) 133415062(ccndx)

PTAO:

133466608(ccndx) 133471835 133478671(ccnd2a)

BPEC:

110161694 110169724

MALB:

109961831(ccnd2) 109963107 109969706

BSPL:

114857066(ccnd2a) 114859827(ccndx) 114862705

SJO:	128358430(ccnd2a) 128379309(ccndx) 128385316

SASA:

100195486(ccnd2) 106561356 106573197(CCND2) 106576262 106601568 106606904

STRU:

115152238 115170698 115180633 115197442 115198916 115204775

OTW:	112214224 112216983 112218786(ccnd2a) 112252585 112259254(ccndx)

OMY:	110487552 110490406 110498391(ccnd2a) 110500074 110523486 110538993

OGO:	123994501 123998998 124003143 124014241 124015383 124034437

ONE:	115107053 115109603 115109930 115133053 115134045

OKI:	109864549 109867280 109883676 109889568 109896687 109897410

OKE:	118366320 118384206 118392456 118395861 118401040(ccnd2a) 127930069

SALP:

111949419 111951371 111953098 111962629 112073327

SNH:	120032172 120034023 120042003 120044064 120049937 120053511(ccnd2a)

CCLU:

121532316 121543531 121548857 121568933 121570386 121576945

ELS:	105012998 105018224(ccnd2) 105020240

SFM:	108918741(ccnd2) 108923882 108931473

PKI:	111836806 111851230 111857566(ccnd2) 111858241

AANG:

118210840(ccnd3) 118231828(ccnd2a)

LOC:	102684393(ccnd3) 102696519(ccnd2)

PSPA:

121318077 121320013

ARUT:

117398003 117415323 117419684 117433893

PSEX:

120522242

LCM:	102345953 102351286(CCND2)

CMK:	103182468 103185578 121852060

RTP:

109931888

CPLA:

122561684(ccnd2a) 122563112(ccnd3)

HOC:	132826741(ccnd2a) 132828362(ccnd3)

LERI:

129707749 129708916(ccnd3)

PMRN:

116945545

LRJ:	133351514 133361804 133361807 133361810 133361815 133362597

BFO:

BBEL:

CIN:

SCLV:

APLC:

ARUN:

AJC:

SKO:	100303589(ccnd)

DME:	Dmel_CG9096(CycD)

DER:

6550709

DSE:

6620005

DSI:	Dsimw501_GD15773(Dsim_GD15773)

DYA:	Dyak_GE16008

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI14224

DHE:

CCAT:

BOD:

BDR:

RZE:	108361682 108377262

AOQ:

TDA:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:	5573724 5575093

AALB:

109426400 109428421 109430528

ASUA:

134207733 134226551

CQU:	CpipJ_CPIJ008538 CpipJ_CPIJ010553 CpipJ_CPIJ014520

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:	100117434(cycD)

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

DPA:

ATD:	109601059 109605401

CSET:

123309437 123309663

AGB:

108911534

LDC:

111502204

DVV:	114336720 126881180

NVL:	108558379 108559855 108564685

APLN:

108741430

PPYR:

116168841 116169802

OTU:	111415202 111415788 111422490

BMOR:

100862781(cycD)

BMAN:

114245331

MSEX:

115448885

DPL:	KGM_207456 KGM_212192B

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:	100164890 100167546

DNX:

107168411

AGS:	114124236 114125104

RMD:	113552279 113556608

ACOO:

126844689 126845434 126846671 126847639

DVT:	126899581 126910345

BTAB:

109039503

CLEC:

106666256

NLU:	111044416 111055176

HVI:	124357973 124363211

PHU:	Phum_PHUM009080 Phum_PHUM503450

FOC:

113210138

TPAL:

117647369 117647975

ZNE:	110829058 110834245

CSEC:

111861374 111865733

SGRE:

126354850

BROR:

134531657 134536469

IEL:	124161864 124162132

FCD:

110851356

DMK:

116919205

DPZ:

124344489

PVM:	113814652 113821812

PJA:	122254541 122260688

PCHN:

PMOO:

HAME:

PCLA:

CQD:	128685329 128688578

PTRU:

123500051

ESN:	126987598 127008860

MNZ:	135207636 135220717

EAF:	111705744 111711144 111711145 111711147 111711439 111711884

LSM:	121118253 121118407 121118478 121118724

PPOI:

119107781 119108536

VDE:

111249597

VJA:

111273965

TUT:	107360664 107363998

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

106466350 106469998 106473353

CEL:	CELE_Y38F1A.5(cyd-1)

CBR:	CBG_02768(Cbr-cyd-1)

HRO:	HELRODRAFT_68430

LGI:	LOTGIDRAFT_190960

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_153660

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_37409

PVY:

116138490

AHF:

112782532

» show all

Reference

PMID:1386336

Authors

Xiong Y, Menninger J, Beach D, Ward DC

Title

Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.

Journal

Genomics 13:575-84 (1992)
DOI:10.1016/0888-7543(92)90127-E

Sequence

[hsa:894]

Reference

PMID:9178893

Authors

Sweeney KJ, Sarcevic B, Sutherland RL, Musgrove EA

Title

Cyclin D2 activates Cdk2 in preference to Cdk4 in human breast epithelial cells.

Journal

Oncogene 14:1329-40 (1997)
DOI:10.1038/sj.onc.1200951

Sequence

[hsa:894]

Reference

PMID:11809706

Authors

Jena N, Deng M, Sicinska E, Sicinski P, Daley GQ

Title

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells.

Journal

Cancer Res 62:535-41 (2002)

Sequence

[mmu:12444]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (38)   
   KEGG PATHWAY (38)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (2873)   
   KEGG GENES (936)   
   KEGG MGENES (95)   
   RefGene (1838)   
   OC (4)   
Literature (3)   
   PubMed (3)   
All databases (2917)   

Download RDF

ORTHOLOGY: K04503

Entry

K04503                      KO

Symbol

CCND1

Name

G1/S-specific cyclin-D1

Pathway

map01522

Endocrine resistance

map04068

FoxO signaling pathway

map04110

Cell cycle

map04115

p53 signaling pathway

map04151

PI3K-Akt signaling pathway

map04152

AMPK signaling pathway

map04218

Cellular senescence

map04310

Wnt signaling pathway

map04340

Hedgehog signaling pathway

map04371

Apelin signaling pathway

map04390

Hippo signaling pathway

map04510

Focal adhesion

map04530

Tight junction

map04630

JAK-STAT signaling pathway

map04917

Prolactin signaling pathway

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04933

AGE-RAGE signaling pathway in diabetic complications

map04934

Cushing syndrome

map04936

Alcoholic liver disease

map05160

Hepatitis C

map05162

Measles

map05163

Human cytomegalovirus infection

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05169

Epstein-Barr virus infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05210

Colorectal cancer

map05212

Pancreatic cancer

map05213

Endometrial cancer

map05214

Glioma

map05215

Prostate cancer

map05216

Thyroid cancer

map05218

Melanoma

map05219

Bladder cancer

map05220

Chronic myeloid leukemia

map05221

Acute myeloid leukemia

map05222

Small cell lung cancer

map05223

Non-small cell lung cancer

map05224

Breast cancer

map05225

Hepatocellular carcinoma

map05226

Gastric cancer

map05416

Viral myocarditis

Disease

H00006

Hairy cell leukemia

H00010

Multiple myeloma

H00016

Oral cancer

H00017

Esophageal cancer

H00020

Colorectal cancer

H00031

Breast cancer

H00055

Laryngeal cancer

H00559

von Hippel-Lindau syndrome

H01464

Mantle cell lymphoma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04340 Hedgehog signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04390 Hippo signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04371 Apelin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04630 JAK-STAT signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04068 FoxO signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04151 PI3K-Akt signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04152 AMPK signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K04503  CCND1; G1/S-specific cyclin-D1
   04115 p53 signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04218 Cellular senescence
    K04503  CCND1; G1/S-specific cyclin-D1
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04503  CCND1; G1/S-specific cyclin-D1
   04530 Tight junction
    K04503  CCND1; G1/S-specific cyclin-D1
09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04921 Oxytocin signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
   04919 Thyroid hormone signaling pathway
    K04503  CCND1; G1/S-specific cyclin-D1
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05206 MicroRNAs in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05205 Proteoglycans in cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05207 Chemical carcinogenesis - receptor activation
    K04503  CCND1; G1/S-specific cyclin-D1
   05203 Viral carcinogenesis
    K04503  CCND1; G1/S-specific cyclin-D1
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05212 Pancreatic cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05225 Hepatocellular carcinoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05226 Gastric cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05214 Glioma
    K04503  CCND1; G1/S-specific cyclin-D1
   05216 Thyroid cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05221 Acute myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05220 Chronic myeloid leukemia
    K04503  CCND1; G1/S-specific cyclin-D1
   05218 Melanoma
    K04503  CCND1; G1/S-specific cyclin-D1
   05219 Bladder cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05215 Prostate cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05213 Endometrial cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05224 Breast cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05222 Small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
   05223 Non-small cell lung cancer
    K04503  CCND1; G1/S-specific cyclin-D1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05160 Hepatitis C
    K04503  CCND1; G1/S-specific cyclin-D1
   05162 Measles
    K04503  CCND1; G1/S-specific cyclin-D1
   05163 Human cytomegalovirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05169 Epstein-Barr virus infection
    K04503  CCND1; G1/S-specific cyclin-D1
   05165 Human papillomavirus infection
    K04503  CCND1; G1/S-specific cyclin-D1
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K04503  CCND1; G1/S-specific cyclin-D1
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04503  CCND1; G1/S-specific cyclin-D1
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04503  CCND1; G1/S-specific cyclin-D1
   04934 Cushing syndrome
    K04503  CCND1; G1/S-specific cyclin-D1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04503  CCND1; G1/S-specific cyclin-D1

Genes

HSA:	595(CCND1)

PTR:	747442(CCND1)

PPS:	100995605(CCND1)

GGO:	101130447(CCND1) 101144860

PON:	100171625(CCND1)

PPYG:

129008462(CCND1)

NLE:	100605736(CCND1)

HMH:	116469117(CCND1)

SSYN:

129478909(CCND1)

MCC:	574320(CCND1)

MCF:	102135329(CCND1)

MTHB:

126935963

MNI:	105469727(CCND1)

CSAB:

103246489(CCND1)

CATY:

105577306(CCND1)

PANU:

101019923(CCND1)

TGE:	112605640(CCND1)

MLEU:

105544506(CCND1)

RRO:	104677168(CCND1)

RBB:	108538745(CCND1)

TFN:	117081518(CCND1)

PTEH:

111522272(CCND1)

CANG:

105512055(CCND1)

CJC:	103796419(CCND1)

SBQ:	101047858(CCND1)

CIMI:

108294139(CCND1)

ANAN:

105717648(CCND1)

CSYR:

103252197(CCND1)

MMUR:

105867511(CCND1)

LCAT:

123642799(CCND1)

PCOQ:

105827423(CCND1)

OGA:	100958947(CCND1)

MMU:	12443(Ccnd1)

MCAL:

110298189(Ccnd1)

MPAH:

110322378(Ccnd1)

RNO:	58919(Ccnd1)

MCOC:

116103285(Ccnd1)

ANU:	117711496(Ccnd1)

MUN:	110546940(Ccnd1)

CGE:	100689063(Ccnd1)

MAUA:

101837554(Ccnd1)

PROB:

127228599(Ccnd1)

PLEU:

114694498(Ccnd1)

MORG:

121454505(Ccnd1) 121457865

MFOT:

126498427

AAMP:

119827335(Ccnd1)

NGI:	103751498(Ccnd1)

HGL:	101712621(Ccnd1)

CPOC:

100729808(Ccnd1)

CCAN:

109696351(Ccnd1)

DORD:

105989065(Ccnd1)

DSP:	122099882(Ccnd1)

PLOP:

125362637(Ccnd1)

NCAR:

124958520

MMMA:

107156886(Ccnd1)

OPI:	101531631(CCND1)

TUP:	102490651(CCND1)

GVR:	103607082(CCND1)

CFA:	449028(CCND1)

CLUD:

112663184(CCND1)

VVP:	112924157(CCND1)

VLG:	121501724(CCND1)

NPO:	129502968(CCND1)

AML:	100469787(CCND1)

UMR:	103671139(CCND1)

UAH:	113243982(CCND1)

UAR:	123778441(CCND1)

ELK:

111149458

LLV:

125078419

MPUF:

101670844(CCND1)

MNP:	132017399(CCND1)

MLK:	131817001(CCND1)

NVS:	122913270(CCND1)

ORO:	101371532(CCND1)

EJU:	114220310(CCND1)

ZCA:	113914083(CCND1)

MLX:	118016166(CCND1)

NSU:	110576391(CCND1)

LWW:	102747216(CCND1)

FCA:	100037407(CCND1)

PYU:	121023852(CCND1)

PBG:	122484101(CCND1)

PVIV:

125176918(CCND1)

LRUF:

124506147

PTG:	102959906(CCND1)

PPAD:

109246902(CCND1)

PUC:

125930010

AJU:

106971167

HHV:	120233874(CCND1)

BTA:	524530(CCND1)

BOM:	102270546(CCND1)

BIU:	109554439(CCND1)

BBUB:

102411133(CCND1)

BBIS:

104987056(CCND1)

CHX:	102169650(CCND1)

OAS:	100144763(CCND1)

BTAX:

128069030(CCND1)

ODA:	120874144(CCND1)

CCAD:

122430666(CCND1)

MBEZ:

129548664(CCND1)

SSC:	100738589(CCND1)

CFR:	102518309(CCND1)

CBAI:

105070367(CCND1)

CDK:	105104393(CCND1)

VPC:	102529872(CCND1)

BACU:

103013404(CCND1)

BMUS:

118898958(CCND1)

LVE:	103090612(CCND1)

OOR:	101273294(CCND1)

DLE:	111183632(CCND1)

PCAD:

102996914(CCND1)

PSIU:

116757387(CCND1)

NASI:

112402178(CCND1)

ECB:	102149114(CCND1)

EAI:	106844248(CCND1)

MYB:	102263484(CCND1)

MYD:	102759793(CCND1)

MMYO:

118665181(CCND1)

MLF:	102441858(CCND1)

MDT:	132241301(CCND1)

PKL:	118712764(CCND1)

EFUS:

103290903(CCND1)

MNA:	107537434(CCND1)

DRO:	112317273(CCND1)

SHON:

118998396(CCND1)

AJM:	119041888(CCND1)

PDIC:

114500683(CCND1)

PHAS:

123829562(CCND1)

MMF:	118628257(CCND1)

PPAM:

129068523(CCND1)

HAI:	109389297(CCND1)

RFQ:	117030194(CCND1)

PALE:

102885330(CCND1)

PGIG:

120584714(CCND1)

PVP:

105307128

RAY:	107503391(CCND1)

MJV:	108388480(CCND1)

TOD:	119246910 119249876(CCND1)

SARA:

101555422(CCND1)

SETR:

126019074(CCND1)

LAV:	100669703(CCND1)

TMU:

101359745

ETF:	101657154(CCND1)

DNM:	101420648(CCND1)

MDO:	100013257(CCND1)

SHR:	100917462(CCND1)

AFZ:

127539835

PCW:	110197171(CCND1)

TVP:	118852949(CCND1)

OAA:	100075081(CCND1)

GGA:	396341(CCND1)

PCOC:

116229085(CCND1)

MGP:	100539759(CCND1)

CJO:	107314428(CCND1)

TPAI:

128086508(CCND1)

LMUT:

125694598(CCND1)

NMEL:

110400907(CCND1)

APLA:

101800639(CCND1)

ACYG:

106044779(CCND1)

CATA:

118250840(CCND1)

AFUL:

116490240(CCND1)

TGU:	100231612(CCND1)

LSR:	110469631(CCND1)

SCAN:

103822217(CCND1)

PMOA:

120509851(CCND1)

OTC:	121339534(CCND1)

PRUF:

121349085(CCND1)

GFR:	102042858(CCND1)

FAB:	101807319(CCND1)

OMA:	130253512(CCND1)

PHI:	102099659(CCND1)

PMAJ:

107205992(CCND1)

CCAE:

111930656(CCND1)

CCW:	104697629(CCND1)

CBRC:

103614709(CCND1)

ETL:	114067926(CCND1)

ZAB:	102063435(CCND1)

ZLE:	135449047(CCND1)

ACHL:

103810712(CCND1)

SVG:	106854769(CCND1)

MMEA:

130577556(CCND1)

HRT:	120754042(CCND1)

SATI:

136362158(CCND1)

FPG:	101914937(CCND1)

FCH:	102053036(CCND1)

CCRI:

104156601(CCND1)

SHAB:

115607412(CCND1)

ACUN:

113481227(CCND1)

TALA:

104362598(CCND1)

ACHC:

115351476(CCND1)

HLE:	104829446(CCND1)

AGEN:

126046852

GCL:

127017416

CSTI:

104552006(CCND1)

LDI:	104341693(CCND1)

MNB:	103774835(CCND1)

DPUB:

104297509(CCND1)

AVIT:

104269354(CCND1)

BRHI:

104488602(CCND1)

EGZ:	104124693(CCND1)

NNI:	104009408(CCND1)

PCRI:

104029611(CCND1)

PCAO:

104051640(CCND1)

PADL:

103925769(CCND1)

AFOR:

103904929(CCND1)

FGA:	104077968(CCND1)

GSTE:

104260603(CCND1)

CLV:	102086245(CCND1)

MUI:	104535334(CCND1)

PGUU:

104471418(CCND1)

PLET:

104617292(CCND1)

CMAC:

104475027(CCND1)

CUCA:

104062258(CCND1)

TEO:	104371160(CCND1)

BREG:

104633930(CCND1)

OHA:	104330745(CCND1)

ACAR:

104527158(CCND1)

CPEA:

104397465(CCND1)

CVF:	104287532(CCND1)

RTD:	128908362(CCND1)

AAM:	106498229(CCND1)

AROW:

112977236(CCND1)

NPD:	112943487(CCND1)

TGT:	104576329(CCND1)

DNE:	112979968(CCND1)

SCAM:

104152854(CCND1)

ASN:	102378816(CCND1)

AMJ:	102563714(CCND1)

CPOO:

109321196(CCND1)

GGN:	109298996(CCND1)

PSS:	102457993(CCND1)

CMY:	102947923(CCND1)

CCAY:

125638229(CCND1)

DCC:	119858104(CCND1)

CPIC:

101943958(CCND1)

TST:	117877043(CCND1)

CABI:

116819583(CCND1)

MRV:	120403684(CCND1)

ACS:	100563772(ccnd1)

ASAO:

132768969(CCND1)

PVT:	110073542(CCND1)

SUND:

121933704(CCND1)

PBI:	103066913(CCND1)

PMUR:

107285821(CCND1)

CTIG:

120316170(CCND1)

TSR:	106546690(CCND1)

PGUT:

117665432(CCND1)

APRI:

131187188(CCND1)

PTEX:

113440315(CCND1)

NSS:	113410261(CCND1)

VKO:	123026251(CCND1)

PMUA:

114596879(CCND1)

PRAF:

128414074(CCND1)

ZVI:	118085960(CCND1)

HCG:	128339433(CCND1)

GJA:	107121511(CCND1)

STOW:

125426154(CCND1)

EMC:	129324627(CCND1)

XLA:	379161(ccnd1.S) 379937(ccnd1.L) 447541 447748(ccndx.L)

XTR:	448045(ccnd1) 548862(ccndx)

NPR:	108785450(CCND1) 108793412

RTEM:

120916056 120917108(CCND1)

BBUF:

120980269(CCND1) 121002136

BGAR:

122920343(CCND1) 122926689

MUO:	115465024 115468768(CCND1)

GSH:	117352052(CCND1) 117368684

DRE:	30222(ccnd1)

SRX:	107727103 107730086

SANH:

107679730 107686820

SGH:	107584710 107594473

CCAR:

109093191(ccnd1)

CAUA:

113051788 113106505

CGIB:

127962195 128016536

PTET:

122348942(ccnd1)

LROH:

127168605(ccnd1)

OMC:	131544494(ccnd1)

PPRM:

120492676(ccnd1)

RKG:	130097285(ccnd1)

MAMB:

125265759(ccnd1)

CIDE:

127516057

CERY:

137030079(ccnd1)

MASI:

127412072 127440653

TROS:

130559793(ccnd1)

TDW:	130424833(ccnd1)

MANU:

129451283(ccnd1)

IPU:

108271119

IFU:	128614260(ccnd1)

PHYP:

113536429(ccnd1)

SMEO:

124391126(ccnd1)

TFD:	113646732(ccnd1)

TVC:	132856637(ccnd1)

TRN:	134331542(ccnd1)

AMEX:

103031956(ccnd1)

CMAO:

118818888(ccnd1)

EEE:	113578962(ccnd1) 113588422

CHAR:

105911298(ccnd1)

TRU:	101061278(ccnd1)

TFS:	130536034(ccnd1)

TNG:	GSTEN00026524G001

LCO:	104937240(ccnd1) 104939589

NCC:	104950786(ccnd1) 104967413

TBEN:

117491260 117496472(ccnd1)

CGOB:

115004643(ccnd1) 115009127

PGEO:

117441044 117448201(ccnd1)

GACU:

117532640 117557335(ccnd1)

EMAC:

134863518(ccnd1) 134882412

ELY:	117257798(ccnd1) 117261946

EFO:	125887563 125902738(ccnd1)

PLEP:

121950245(ccnd1) 121964485 121964884

SLUC:

116040204 116041081(ccnd1)

ECRA:

117946450(ccnd1) 117948766

ESP:	116694578 116703178(ccnd1)

PFLV:

114552928(ccnd1) 114560618

GAT:	120812234(ccnd1) 120812565 120812806

PPUG:

119196637 119196950(ccnd1)

AFB:	129102238(ccnd1) 129108229

CLUM:

117727345(ccnd1) 117732710

PSWI:

130192280(ccnd1) 130194907

MSAM:

119890260(ccnd1) 119894289

SCHU:

122875207 122876462(ccnd1)

CUD:	121512170(ccnd1) 121514619

ALAT:

119017665(ccnd1) 119025008

MZE:	101467298 101485361(ccnd1)

ONL:	100691051(ccnd1) 100691373

OAU:	116331023 116332748(ccnd1)

OLA:	101169672(ccnd1)

OML:	112141930(ccnd1)

CSAI:

133457669(ccnd1)

XMA:	102233074(ccnd1)

XCO:	114143123(ccnd1)

XHE:	116719094(ccnd1)

PRET:

103462287(ccnd1)

PFOR:

103150949(ccnd1)

PLAI:

106941969(ccnd1)

PMEI:

106911618(ccnd1)

GAF:	122819633(ccnd1)

PPRL:

129353217(ccnd1)

CVG:	107096221(ccnd1)

CTUL:

119795187(ccnd1)

GMU:	124867399(ccnd1)

NFU:	107374449(ccnd1)

KMR:	108237918(ccnd1)

ALIM:

106510985(ccnd1)

NWH:	119423918(ccnd1)

AOCE:

111576239(ccnd1)

MCEP:

125005752(ccnd1) 125014367

CSEM:

103379080 103379853(ccnd1)

POV:	109625110(ccnd1) 109642994

SSEN:

122776245(ccnd1) 122776506

HHIP:

117759437(ccnd1) 117762757

HSP:	118110121 118113286(ccnd1)

PPLT:

128449886(ccnd1)

SMAU:

118302431(ccnd1) 118314882

LCF:	108877824 108879779 108884596

SDU:	111221119(ccnd1) 111234824

SLAL:

111647809 111669291(ccnd1) 111670038

XGL:	120792411(ccnd1) 120793380(zgc:158868)

BPEC:

110169262(ccnd1) 110174870

MALB:

109967859(ccnd1)

BSPL:

114852499(ccnd1)

SJO:	128358362(ccnd1) 128359220

SASA:

100306852(ccnd1) 106561617 106562055 106587137

STRU:

115152358 115167492 115197603 115202965

OTW:	112218887 112249039 112252678 112263573

OMY:	110499952 110506401 110524590 110526228(ccnd1)

OGO:	124004130 124033208 124033899 124035824

ONE:	115109686 115112096 115113563

OKI:	109867514 109885836 109889644 109895467

OKE:	118358618 118393712(ccnd1) 118398791 118400945

SALP:

111952420 111969292 111974408 112070040

SNH:	120025309 120045999 120054165 120066776

CCLU:

121531644 121557697 121573328 121577046

ELS:	105017289(ccnd1) 105018279

SFM:	108940463 108941209(ccnd1)

PKI:

111851863

AANG:

118215511 118228076

LOC:	102687804(ccnd1)

PSPA:

121295125 121305898(ccndx) 121329999

ARUT:

117432035(ccnd1) 117435119

PSEX:

120525945(ccnd1) 120542830

LCM:	102361167(CCND1) 102367471

CMK:	121850328(ccnd1)

RTP:	109919627(ccnd1) 109925537

CPLA:

122541966 122557612(ccnd1)

HOC:	132824516(ccnd1) 132831194

LERI:

129705590(ccnd1)

PMRN:

116952278

LRJ:

133347528

SPU:	115927903 373245

LPIC:

TCA:

HAME:

EAF:

FCY:	FRACYDRAFT_140762(dsCyc9b)

» show all

Reference

PMID:1826542

Authors

Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM, Arnold A

Title

A novel cyclin encoded by a bcl1-linked candidate oncogene.

Journal

Nature 350:512-5 (1991)
DOI:10.1038/350512a0

Sequence

[hsa:595]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (96)   
   KEGG PATHWAY (96)   
Disease (9)   
   KEGG DISEASE (9)   
Drug (1)   
   KEGG DRUG (1)   
Gene (966)   
   KEGG GENES (501)   
   KEGG MGENES (117)   
   RefGene (344)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (1074)   

Download RDF

ORTHOLOGY: K10152

Entry

K10152                      KO

Symbol

CCND3

Name

G1/S-specific cyclin-D3

Pathway

map04110

Cell cycle

map04115

p53 signaling pathway

map04151

PI3K-Akt signaling pathway

map04218

Cellular senescence

map04310

Wnt signaling pathway

map04390

Hippo signaling pathway

map04510

Focal adhesion

map04630

JAK-STAT signaling pathway

map05162

Measles

map05164

Influenza A

map05165

Human papillomavirus infection

map05166

Human T-cell leukemia virus 1 infection

map05169

Epstein-Barr virus infection

map05200

Pathways in cancer

map05203

Viral carcinogenesis

map05207

Chemical carcinogenesis - receptor activation

Disease

H00010

Multiple myeloma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04390 Hippo signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04630 JAK-STAT signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04151 PI3K-Akt signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K10152  CCND3; G1/S-specific cyclin-D3
   04115 p53 signaling pathway
    K10152  CCND3; G1/S-specific cyclin-D3
   04218 Cellular senescence
    K10152  CCND3; G1/S-specific cyclin-D3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K10152  CCND3; G1/S-specific cyclin-D3
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K10152  CCND3; G1/S-specific cyclin-D3
   05207 Chemical carcinogenesis - receptor activation
    K10152  CCND3; G1/S-specific cyclin-D3
   05203 Viral carcinogenesis
    K10152  CCND3; G1/S-specific cyclin-D3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10152  CCND3; G1/S-specific cyclin-D3
   05164 Influenza A
    K10152  CCND3; G1/S-specific cyclin-D3
   05162 Measles
    K10152  CCND3; G1/S-specific cyclin-D3
   05169 Epstein-Barr virus infection
    K10152  CCND3; G1/S-specific cyclin-D3
   05165 Human papillomavirus infection
    K10152  CCND3; G1/S-specific cyclin-D3

Genes

HSA:	896(CCND3)

PTR:	462689(CCND3)

PPS:	100972595(CCND3)

GGO:	101130628(CCND3)

PON:	100452570(CCND3)

PPYG:

129039518(CCND3)

NLE:	100580170(CCND3)

HMH:	116460133(CCND3)

SSYN:

129473618(CCND3)

MCC:	695215(CCND3)

MCF:	101865999(CCND3)

MTHB:

126953804

MNI:	105489611(CCND3)

CSAB:

103221504(CCND3)

CATY:

105591815(CCND3)

PANU:

100137215(CCND3)

TGE:	112622480(CCND3)

MLEU:

105544297(CCND3)

RRO:	104667309(CCND3)

RBB:	108533501(CCND3)

TFN:	117087209(CCND3)

PTEH:

111543039(CCND3)

CANG:

105513014(CCND3)

CJC:	100408249(CCND3)

SBQ:	101047749(CCND3)

CIMI:

108317085(CCND3)

ANAN:

105714624(CCND3) 135268097

CSYR:

103264876(CCND3)

MMUR:

105875858(CCND3)

LCAT:

123631868(CCND3)

PCOQ:

105807480(CCND3)

OGA:	100945148(CCND3)

MMU:	12445(Ccnd3)

MCAL:

110312516(Ccnd3)

MPAH:

110335402(Ccnd3)

RNO:	25193(Ccnd3)

MCOC:

116075067(Ccnd3)

ANU:	117722295(Ccnd3)

MUN:	110550225(Ccnd3)

CGE:	100766025(Ccnd3)

MAUA:

101829610(Ccnd3)

PROB:

127214752 127236785(Ccnd3)

PLEU:

114705331(Ccnd3)

MORG:

121450483(Ccnd3)

MFOT:

126488908

AAMP:

119823258(Ccnd3)

NGI:	103725891(Ccnd3)

HGL:	101708062(Ccnd3)

CPOC:

100718785(Ccnd3)

CCAN:

109682157(Ccnd3)

DORD:

105987818(Ccnd3)

DSP:	122101503(Ccnd3)

PLOP:

125352590(Ccnd3)

NCAR:

124988186

MMMA:

107143908(Ccnd3)

OCU:

100009038

OPI:	101535218(CCND3)

TUP:	102499577(CCND3)

GVR:	103587459(CCND3)

CFA:	608847(CCND3)

CLUD:

112641579(CCND3)

VVP:	112913983(CCND3)

VLG:	121499073(CCND3)

NPO:	129512587(CCND3)

AML:	100479467(CCND3)

UMR:	103664092(CCND3)

UAH:	113261302(CCND3)

UAR:	123779180(CCND3)

ELK:

111147855

LLV:

125102808

MPUF:

101689940(CCND3)

MNP:	132018063(CCND3)

MLK:	131833967(CCND3)

NVS:	122908116(CCND3)

ORO:	101372891(CCND3)

EJU:	114204469(CCND3)

ZCA:	113926716(CCND3)

MLX:	118001139(CCND3)

NSU:	110582036(CCND3)

LWW:	102736121(CCND3)

FCA:	101101311(CCND3)

PYU:	121029442(CCND3)

PCOO:

112862913(CCND3)

PBG:	122489512(CCND3)

PVIV:

125165233(CCND3)

LRUF:

124528816

PTG:	102970915(CCND3)

PPAD:

109271613(CCND3)

PUC:

125938244

AJU:

106974052

HHV:	120238692(CCND3)

BTA:	540547(CCND3)

BOM:	102268077(CCND3)

BIU:	109577151(CCND3)

BBUB:

102412107(CCND3)

BBIS:

105005247(CCND3)

CHX:	102190470(CCND3)

OAS:	100147798(CCND3)

BTAX:

128055411(CCND3)

ODA:	120870130(CCND3)

CCAD:

122429373(CCND3)

MBEZ:

129543836(CCND3)

SSC:	780426(CCND3)

CFR:	102524562(CCND3)

CBAI:

105083774(CCND3)

CDK:	105086756(CCND3)

VPC:	102526417(CCND3)

BACU:

103007761(CCND3)

BMUS:

118903037(CCND3)

LVE:	103072491(CCND3)

OOR:	101274576(CCND3)

DLE:	111178811(CCND3)

PCAD:

102987349(CCND3)

PSIU:

116762780(CCND3)

NASI:

112413996(CCND3)

ECB:	100066590(CCND3)

EPZ:	103563494(CCND3)

EAI:	106824516(CCND3)

MYB:	102252389(CCND3)

MYD:	102756923(CCND3)

MMYO:

118660354(CCND3)

MLF:	102435083(CCND3)

MDT:	132237332(CCND3)

PKL:	118705228(CCND3)

EFUS:

103301919(CCND3)

MNA:	107536896(CCND3)

DRO:	112302074(CCND3)

SHON:

118991404(CCND3)

AJM:	119056484(CCND3)

PDIC:

114494075(CCND3)

PHAS:

123821479(CCND3)

MMF:	118621102(CCND3)

PPAM:

129067448(CCND3)

HAI:	109382891(CCND3)

RFQ:	117017078(CCND3)

PALE:

102881884(CCND3)

PGIG:

120596338(CCND3)

PVP:	105288434(CCND3)

RAY:	107501938(CCND3)

MJV:	108405335(CCND3)

TOD:	119252455(CCND3)

SARA:

101541507(CCND3)

SETR:

125995979(CCND3)

LAV:	100668683(CCND3)

TMU:

101351688

ETF:	101639447(CCND3)

DNM:	101427751(CCND3)

MDO:	100027538(CCND3)

GAS:	123245608(CCND3)

SHR:	100921166(CCND3)

AFZ:

127561736

PCW:	110203289(CCND3)

TVP:	118856206(CCND3)

OAA:	100088334(CCND3)

GGA:	419928(CCND3)

PCOC:

116236965(CCND3)

MGP:	100546832(CCND3)

CJO:	107324823(CCND3)

TPAI:

128087997(CCND3)

LMUT:

125684090(CCND3)

NMEL:

110388224(CCND3)

APLA:

101790685(CCND3)

ACYG:

106045863(CCND3)

CATA:

118255260(CCND3)

AFUL:

116498945(CCND3)

TGU:	100218837(CCND3)

LSR:	110477163(CCND3)

SCAN:

115484353(CCND3)

PMOA:

120495869(CCND3)

OTC:	121347958(CCND3)

PRUF:

121354002(CCND3)

GFR:	102033692(CCND3)

FAB:	101819978(CCND3)

OMA:	130263667(CCND3)

PHI:	102106455(CCND3)

PMAJ:

107214873

CCAE:

111939904(CCND3)

CCW:	104692524(CCND3)

CBRC:

103625312(CCND3)

ETL:	114067504 114071008

ZLE:	135458002(CCND3)

ACHL:

103799979

SVG:	106851012(CCND3)

MMEA:

130586210(CCND3)

HRT:	120762882(CCND3)

SATI:

136371685(CCND3)

FPG:	101913539(CCND3)

FCH:	102059828(CCND3)

CCRI:

104161835(CCND3)

NNT:

104407973

SHAB:

115602480(CCND3)

ACUN:

113488829(CCND3)

TALA:

104361497(CCND3)

ACHC:

115335097(CCND3)

HALD:

104321311

HLE:	104842404(CCND3)

AGEN:

126052028

GCL:

127026163

CSTI:

104559135(CCND3)

LDI:	104352406(CCND3)

DPUB:

104305350(CCND3)

AVIT:

104281273(CCND3)

BRHI:

104499033(CCND3)

EGZ:	104125735(CCND3)

NNI:	104013148(CCND3)

PCRI:

104036009(CCND3)

PCAO:

104049627(CCND3)

PADL:

103919864(CCND3)

AFOR:

103893621(CCND3)

FGA:	104077578(CCND3)

GSTE:

104258073(CCND3)

CLV:	102090134(CCND3)

MUI:

104538159

PGUU:

104466361

PLET:

104626904

EHS:	104516127(CCND3)

CMAC:

104483377(CCND3)

CUCA:

104067105(CCND3)

TEO:	104376841(CCND3)

BREG:

104642325(CCND3)

ACAR:

104527277

CPEA:

104397134(CCND3)

CVF:	104289311(CCND3)

RTD:	128900226(CCND3)

AAM:	106483949(CCND3)

AROW:

112973433(CCND3)

NPD:	112959195(CCND3)

TGT:	104574446(CCND3)

DNE:	112990171(CCND3)

SCAM:

104146463(CCND3)

ASN:	102386423(CCND3)

AMJ:	102560290(CCND3)

CPOO:

109317772(CCND3)

GGN:	109295394(CCND3)

PSS:	102445982(CCND3)

CMY:	102940098(CCND3)

CCAY:

125624926(CCND3)

DCC:	119846188(CCND3)

CPIC:

101940970(CCND3)

TST:	117875833(CCND3)

CABI:

116827931(CCND3)

MRV:	120405147(CCND3)

ACS:	100566165(ccnd3)

ASAO:

132773669(CCND3)

PVT:	110078878 110080664(CCND3)

SUND:

121928487(CCND3) 121936975

PBI:	103060947(CCND3)

PMUR:

107293964(CCND3)

CTIG:

120306647(CCND3)

TSR:	106540193(CCND3)

PGUT:

117663931 132711273(CCND3)

PTEX:

113446116(CCND3)

NSS:	113418146(CCND3)

VKO:	123030876(CCND3)

PMUA:

114599266(CCND3)

PRAF:

128416065(CCND3)

ZVI:	118088329(CCND3)

HCG:	128322958(CCND3)

GJA:	107119188(CCND3)

STOW:

125433053(CCND3)

EMC:	129330771(CCND3)

RTEM:

120927190(CCND3)

MUO:	115481462(CCND3)

GSH:	117347830(CCND3)

DRE:	449996(ccnd3)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122327986(ccnd3)

LROH:

127153789(ccnd3)

OMC:	131529954(ccnd3)

PPRM:

120486302(ccnd3)

RKG:	130072755(ccnd3)

MAMB:

125263038(ccnd3)

CIDE:

127520610

CERY:

137029323(ccnd3)

MASI:

127438397

TROS:

130548607(ccnd3)

TDW:	130430282(ccnd3)

MANU:

129453249(ccnd3)

IPU:

108281084

IFU:	128624720(ccnd3)

PHYP:

113539684(ccnd3)

SMEO:

124377219(ccnd3)

TFD:	113648722(ccnd3)

TVC:	132837892(ccnd3)

TRN:	134301655(ccnd3)

AMEX:

103045792(ccnd3)

CMAO:

118799422(ccnd3)

EEE:	113586952 113587140

CHAR:

105897896(ccnd3)

TRU:	101063905(ccnd3)

TFS:	130523793(ccnd3)

LCO:	104927998(ccnd3)

NCC:

104957029

TBEN:

117489997(ccnd3)

CGOB:

115008042

PGEO:

117446571(ccnd3)

GACU:

117551118(ccnd3)

EMAC:

134883501(ccnd3)

ELY:	117257102(ccnd3)

EFO:	125905662(ccnd3)

PLEP:

121956400(ccnd3)

SLUC:

116041604(ccnd3)

ECRA:

117943266(ccnd3)

ESP:

116687691

PFLV:

114553865

GAT:	120835040(ccnd3)

PPUG:

119229889(ccnd3)

CLUM:

117730674(ccnd3)

PSWI:

130208146(ccnd3)

MSAM:

119886218(ccnd3)

SCHU:

122884401(ccnd3)

CUD:	121507399(ccnd3)

ALAT:

119020831(ccnd3)

MZE:	101472513(ccnd3)

ONL:

100690263

OAU:	116333801(ccnd3)

OLA:

101165722

OML:	112144604(ccnd3)

CSAI:

133449140(ccnd3)

XMA:

102221373

XCO:

114136140

XHE:

116710801

PRET:

103465178(ccnd3)

PFOR:

103150666(ccnd3)

PLAI:

106954847(ccnd3)

PMEI:

106924289(ccnd3)

GAF:	122834614(ccnd3)

PPRL:

129355918(ccnd3)

CVG:	107085628(ccnd3)

CTUL:

119779972(ccnd3)

GMU:	124856377(ccnd3)

NFU:	107385769(ccnd3)

KMR:	108235802(ccnd3)

ALIM:

106516142(ccnd3)

NWH:	119412827(ccnd3)

AOCE:

111574366

MCEP:

125007216(ccnd3)

CSEM:

103385889(ccnd3)

POV:	109629233(ccnd3)

SSEN:

122767976(ccnd3)

HHIP:

117761231(ccnd3)

HSP:	118103957(ccnd3)

PPLT:

128461745(ccnd3)

SMAU:

118309273(ccnd3)

LCF:

108886479

SDU:

111222077

SLAL:

111660864(ccnd3)

XGL:	120807092(ccnd3)

HCQ:

109522291

SSCV:

125977269

SBIA:

133507684(ccnd3)

PEE:	133408781(ccnd3)

BPEC:

110168781

MALB:

109964433(ccnd3)

BSPL:

114855831(ccnd3)

SJO:	128355266(ccnd3)

SASA:

106583090

STRU:

115150620

OTW:	112254562(ccnd3)

OMY:	110528077(ccnd3)

OGO:	124004172(ccnd3) 124031320

ONE:

115145890

OKI:

109891102

OKE:	118400278 127931913

SALP:

111970058

SNH:

120065733

CCLU:

121577651

ELS:	105017123(ccnd3)

PKI:	111852988(ccnd3)

PSPA:

121299920 121299948 121304753

PSEX:

120536445(ccnd3) 120543191

FVI:

122538402

SOY:	115874553 115874712

AGRG:

126737730

ATD:

109601133

AGB:

108909684

LDC:	111506239 111508983

APLN:

108738019

BMAN:

114241730

MSEX:

115445851

DPL:	KGM_211878

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PGW:

LGLY:

CCRN:

BTAB:

DCI:

HHAL:

MQU:	128986496 128989651 128989868

FOC:

113217066

DPX:	DAPPUDRAFT_46610

DMK:

PCHN:

PMOO:

PCLA:

PTRU:

HAZT:

108671729 108673623 108673631

LSM:	121118004 121118395

TCF:	131877336 131877338 131877623 131877865 131877923

PPOI:

119091661 119091841 119092383

DSV:	119463332 119463999 119464896

RSAN:

119401763 119401841 119403207

RMP:	119164328 119165135 119165314

VDE:

VJA:

CSCU:

CVS:

PTEP:

UDV:

SDM:

LPOL:

106458046 106460964 106477433

TSP:

Tsp_06217

HRO:	HELRODRAFT_92475

» show all

Reference

PMID:15358120

Authors

Liu W, Sun M, Jiang J, Shen X, Sun Q, Liu W, Shen H, Gu J

Title

Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity.

Journal

Biochem Biophys Res Commun 321:954-60 (2004)
DOI:10.1016/j.bbrc.2004.07.053

Sequence

[hsa:896]

Reference

PMID:1383201

Authors

Motokura T, Keyomarsi K, Kronenberg HM, Arnold A

Title

Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 proto-oncogene.

Journal

J Biol Chem 267:20412-5 (1992)

Sequence

[hsa:896]

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   KEGG GENES (473)   
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