KEGG ORTHOLOGY: K10160

ORTHOLOGY: K10160

Entry

K10160                      KO

Symbol

TLR4, CD284

Name

toll-like receptor 4

Pathway

map04064

NF-kappa B signaling pathway

map04066

HIF-1 signaling pathway

map04145

Phagosome

map04151

PI3K-Akt signaling pathway

map04217

Necroptosis

map04613

Neutrophil extracellular trap formation

map04620

Toll-like receptor signaling pathway

map04621

NOD-like receptor signaling pathway

map04936

Alcoholic liver disease

map05130

Pathogenic Escherichia coli infection

map05131

Shigellosis

map05132

Salmonella infection

map05133

Pertussis

map05134

Legionellosis

map05135

Yersinia infection

map05140

Leishmaniasis

map05142

Chagas disease

map05144

Malaria

map05145

Toxoplasmosis

map05146

Amoebiasis

map05152

Tuberculosis

map05161

Hepatitis B

map05162

Measles

map05164

Influenza A

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05205

Proteoglycans in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05321

Inflammatory bowel disease

map05323

Rheumatoid arthritis

map05417

Lipid and atherosclerosis

Disease

H00821

Age-related macular degeneration

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K10160  TLR4, CD284; toll-like receptor 4
   04066 HIF-1 signaling pathway
    K10160  TLR4, CD284; toll-like receptor 4
   04151 PI3K-Akt signaling pathway
    K10160  TLR4, CD284; toll-like receptor 4
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K10160  TLR4, CD284; toll-like receptor 4
  09143 Cell growth and death
   04217 Necroptosis
    K10160  TLR4, CD284; toll-like receptor 4
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K10160  TLR4, CD284; toll-like receptor 4
   04620 Toll-like receptor signaling pathway
    K10160  TLR4, CD284; toll-like receptor 4
   04621 NOD-like receptor signaling pathway
    K10160  TLR4, CD284; toll-like receptor 4
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K10160  TLR4, CD284; toll-like receptor 4
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K10160  TLR4, CD284; toll-like receptor 4
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K10160  TLR4, CD284; toll-like receptor 4
   05161 Hepatitis B
    K10160  TLR4, CD284; toll-like receptor 4
   05171 Coronavirus disease - COVID-19
    K10160  TLR4, CD284; toll-like receptor 4
   05164 Influenza A
    K10160  TLR4, CD284; toll-like receptor 4
   05162 Measles
    K10160  TLR4, CD284; toll-like receptor 4
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K10160  TLR4, CD284; toll-like receptor 4
   05132 Salmonella infection
    K10160  TLR4, CD284; toll-like receptor 4
   05131 Shigellosis
    K10160  TLR4, CD284; toll-like receptor 4
   05135 Yersinia infection
    K10160  TLR4, CD284; toll-like receptor 4
   05133 Pertussis
    K10160  TLR4, CD284; toll-like receptor 4
   05134 Legionellosis
    K10160  TLR4, CD284; toll-like receptor 4
   05152 Tuberculosis
    K10160  TLR4, CD284; toll-like receptor 4
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K10160  TLR4, CD284; toll-like receptor 4
   05144 Malaria
    K10160  TLR4, CD284; toll-like receptor 4
   05145 Toxoplasmosis
    K10160  TLR4, CD284; toll-like receptor 4
   05140 Leishmaniasis
    K10160  TLR4, CD284; toll-like receptor 4
   05142 Chagas disease
    K10160  TLR4, CD284; toll-like receptor 4
  09163 Immune disease
   05323 Rheumatoid arthritis
    K10160  TLR4, CD284; toll-like receptor 4
   05321 Inflammatory bowel disease
    K10160  TLR4, CD284; toll-like receptor 4
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K10160  TLR4, CD284; toll-like receptor 4
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K10160  TLR4, CD284; toll-like receptor 4
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K10160  TLR4, CD284; toll-like receptor 4
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K10160  TLR4, CD284; toll-like receptor 4
   04090 CD molecules
    K10160  TLR4, CD284; toll-like receptor 4
   00536 Glycosaminoglycan binding proteins
    K10160  TLR4, CD284; toll-like receptor 4
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Toll-like receptors
    K10160  TLR4, CD284; toll-like receptor 4
Pattern recognition receptors [BR:ko04054]
Membrane-bound pattern recognition receptors
  Toll-like receptors
   K10160  TLR4, CD284; toll-like receptor 4
CD molecules [BR:ko04090]
Proteins
  K10160  CD284, TLR4; toll-like receptor 4
Glycosaminoglycan binding proteins [BR:ko00536]
Hyaluronan
  Cell surface receptors
   K10160  TLR4, CD284; toll-like receptor 4

Genes

HSA:	7099(TLR4)

PTR:	743242(TLR4)

PPS:	100980644(TLR4)

GGO:	101148715(TLR4)

PON:	100457237(TLR4)

PPYG:

129044357(TLR4)

NLE:	100601154(TLR4)

HMH:	116475593(TLR4)

SSYN:

129478959(TLR4)

MCC:	574360(TLR4)

MCF:	102136906(TLR4)

MTHB:

126936830

MNI:	105487117(TLR4)

CSAB:

103218937(TLR4)

CATY:

105600415(TLR4)

PANU:

101009041(TLR4)

TGE:	112608006(TLR4)

MLEU:

105534560(TLR4)

RRO:	104658520(TLR4)

RBB:	108530054(TLR4)

TFN:	117098762(TLR4)

PTEH:

111550322(TLR4)

CANG:

105517525(TLR4)

CJC:	100399012(TLR4)

SBQ:	101043935(TLR4)

CIMI:

108286470(TLR4)

ANAN:

105731135(TLR4)

CSYR:

103255573(TLR4)

MMUR:

105873668(TLR4)

LCAT:

123646094(TLR4)

PCOQ:

105826455(TLR4)

OGA:	100956359(TLR4)

MMU:	21898(Tlr4)

MCAL:

110293229(Tlr4)

MPAH:

110323586(Tlr4)

RNO:	29260(Tlr4)

MCOC:

116096145(Tlr4)

ANU:	117709586(Tlr4)

MUN:	110565332(Tlr4)

CGE:	100689329(Tlr4)

MAUA:

101824088(Tlr4)

PROB:

127224882(Tlr4)

PLEU:

114705782(Tlr4)

MORG:

121433864(Tlr4)

MFOT:

126507954

AAMP:

119818005(Tlr4)

NGI:	103734505(Tlr4)

HGL:	101715916(Tlr4)

CPOC:

100724803(Tlr4)

CCAN:

109700701(Tlr4)

DORD:

105996175(Tlr4)

DSP:	122107098(Tlr4)

PLOP:

125347394(Tlr4)

NCAR:

124964909

MMMA:

107152144(Tlr4)

OCU:	100009497(TLR4)

OPI:	101536535(TLR4)

TUP:	102501464(TLR4)

GVR:	103602848(TLR4)

CFA:	403417(TLR4)

CLUD:

112650004(TLR4)

VVP:	112923099(TLR4)

VLG:	121496246(TLR4)

NPO:	129494517(TLR4)

AML:	100472815(TLR4)

UMR:	103670382(TLR4)

UAH:	113266343(TLR4)

UAR:	123788027(TLR4)

ELK:

111146042

LLV:

125083203

MPUF:

101690347(TLR4)

MNP:	132024470(TLR4)

MLK:	131812598(TLR4)

NVS:	122917312(TLR4)

ORO:	101371071(TLR4)

EJU:	114212737(TLR4)

ZCA:	113934760(TLR4)

MLX:	118017761(TLR4)

NSU:	110581529(TLR4)

LWW:	102749618(TLR4)

FCA:	493698(TLR4)

PYU:	121034896(TLR4)

PCOO:

112860159(TLR4)

PBG:	122475419(TLR4)

PVIV:

125150458(TLR4)

LRUF:

124503507

PTG:	102959529(TLR4)

PPAD:

109269905(TLR4)

PUC:

125920696

AJU:

106977278

HHV:	120240966(TLR4)

BTA:	281536(TLR4)

BOM:	102288174(TLR4)

BIU:	109563399(TLR4)

BBUB:

102407022(TLR4)

BBIS:

104994776(TLR4)

CHX:	100860955(TLR4)

OAS:	554263(TLR4)

BTAX:

128052396(TLR4)

ODA:	120864691(TLR4)

CCAD:

122431924(TLR4)

MBEZ:

129557207(TLR4)

SSC:	399541(TLR4)

CFR:	102522349(TLR4)

CBAI:

105070721(TLR4)

CDK:	105104576(TLR4)

VPC:	102529688(TLR4)

BACU:

103015759(TLR4)

BMUS:

118897312(TLR4)

LVE:	103074659(TLR4)

OOR:	101282217(TLR4)

DLE:	111177277(TLR4)

PCAD:

102983076(TLR4)

PSIU:

116755398(TLR4)

NASI:

112411200(TLR4)

ECB:	100066890(TLR4) 111771935

EPZ:	103562040(TLR4)

EAI:	106824214(TLR4)

MYB:	102253644(TLR4)

MYD:	102756242(TLR4)

MMYO:

118667106(TLR4)

MLF:	102437402(TLR4)

MDT:	132212331(TLR4)

PKL:	118716098(TLR4)

EFUS:

103295671(TLR4)

MNA:	107537636(TLR4)

DRO:	112306266(TLR4)

SHON:

118995970(TLR4)

AJM:	119056324(TLR4)

PDIC:

114510836(TLR4)

PHAS:

123820226(TLR4)

MMF:	118629497(TLR4)

PPAM:

129079317(TLR4)

HAI:	109385740(TLR4)

RFQ:	117032253(TLR4)

PALE:

102897365(TLR4)

PGIG:

120605781(TLR4)

PVP:	105292652(TLR4)

RAY:	107514466(TLR4)

MJV:	108400680(TLR4)

TOD:	119232116(TLR4)

SARA:

101548691(TLR4)

SETR:

126009607(TLR4)

LAV:	100654493(TLR4)

TMU:

101353470

ETF:	101660600(TLR4)

DNM:	101436464(TLR4)

MDO:	100014467(TLR4)

GAS:	123235393(TLR4)

SHR:	100927125(TLR4)

AFZ:

127550519

PCW:	110211357(TLR4)

TVP:	118840860(TLR4)

OAA:	114811053(TLR4)

GGA:	417241(TLR4)

PCOC:

116234179(TLR4)

MGP:	100540712(TLR4)

CJO:	107321682(TLR4)

TPAI:

128074093(TLR4)

LMUT:

125702708(TLR4)

NMEL:

110406939(TLR4)

APLA:

101799388(TLR4)

ACYG:

106037141(TLR4)

CATA:

118252184(TLR4)

AFUL:

116496923(TLR4)

TGU:	100216357(TLR4)

LSR:	110482234(TLR4)

SCAN:

103819051(TLR4)

PMOA:

120507511(TLR4)

OTC:	121336957(TLR4)

PRUF:

121357685(TLR4)

GFR:	102037892(TLR4)

FAB:	101813378(TLR4)

OMA:	130260187(TLR4)

PHI:	102101350(TLR4)

PMAJ:

107211898(TLR4)

CCAE:

111936941(TLR4)

CCW:	104688244(TLR4)

CBRC:

103619761(TLR4)

ETL:	114054565(TLR4)

ZAB:	102066609(TLR4)

ZLE:	135454965(TLR4)

ACHL:

103800748(TLR4)

SVG:	106851398(TLR4)

MMEA:

130580416(TLR4)

HRT:	120761701(TLR4)

SATI:

136369572(TLR4)

FPG:	101922930(TLR4)

FCH:	102055613(TLR4)

CCRI:

104163441(TLR4)

NNT:	104405963(TLR4)

SHAB:

115617148(TLR4)

ACUN:

113486459(TLR4)

TALA:

104363890(TLR4)

ACHC:

115335358(TLR4)

HALD:

104315685(TLR4)

HLE:	104833958(TLR4)

AGEN:

126052181

GCL:

127023661

CSTI:

104553328(TLR4)

LDI:	104343793(TLR4)

MNB:	103777492(TLR4)

DPUB:

104306136(TLR4)

AVIT:

104272743(TLR4)

BRHI:

104494590(TLR4)

EGZ:	104122702(TLR4)

NNI:	104022122(TLR4)

PCRI:

104030095(TLR4)

PCAO:

104052918(TLR4)

PADL:

103912903(TLR4)

AFOR:

103901380(TLR4)

FGA:	104083104(TLR4)

GSTE:

104255144(TLR4)

CLV:	102096659(TLR4)

MUI:	104547901(TLR4)

PGUU:

104461937(TLR4)

PLET:

104625786(TLR4)

EHS:	104513030(TLR4)

CMAC:

104484970(TLR4)

CUCA:

104066770(TLR4)

TEO:	104373107(TLR4)

BREG:

104636809(TLR4)

OHA:	104330230(TLR4)

ACAR:

104522704(TLR4)

CPEA:

104397933(TLR4)

CVF:	104289137(TLR4)

RTD:	128917628(TLR4)

AAM:	106499946(TLR4)

AROW:

112963054(TLR4)

NPD:	112955980(TLR4)

TGT:	104572062(TLR4)

DNE:	112991331(TLR4)

SCAM:

104139792(TLR4)

ASN:	102383551(TLR4)

AMJ:	102574232(TLR4)

CPOO:

109313858(TLR4)

GGN:	109292881(TLR4)

PSS:	102448887(TLR4)

CMY:	102941701(TLR4)

CCAY:

125623505(TLR4)

DCC:	119844229(TLR4)

CPIC:

101954201(TLR4)

TST:	117867273(TLR4)

CABI:

116835169(TLR4)

MRV:	120386592(TLR4)

ACS:	100559216(tlr4)

ASAO:

132763647(TLR4)

PVT:	110088887(TLR4)

SUND:

121936774(TLR4)

PBI:	103060306(TLR4)

PMUR:

107285740(TLR4)

CTIG:

120298812(TLR4)

TSR:	106546496(TLR4)

PGUT:

117656869(TLR4)

APRI:

131186010(TLR4)

PTEX:

113443881(TLR4)

NSS:	113426496(TLR4)

VKO:	123028389(TLR4)

PMUA:

114589367(TLR4)

PRAF:

128406350(TLR4)

ZVI:	118083676(TLR4)

HCG:	128338801(TLR4)

GJA:	107106055(TLR4)

STOW:

125441539(TLR4)

EMC:	129341810(TLR4)

XLA:

108700046

NPR:

108794768

RTEM:

120913060(TLR4)

BBUF:

120977785(TLR4)

BGAR:

122946542(TLR4)

MUO:	115472530(TLR4)

GSH:	117367365(TLR4)

DRE:	403131(tlr4ba) 403132(tlr4bb) 795671(tlr4al)

SRX:	107708380 107708382 107708458 107747448

SANH:

107678592 107678593 107690165 107690199

SGH:	107576986 107582517

CCAR:

109100795

CAUA:

113057155 113057156 113057539 113112929

CGIB:

127969856 127969859 127969860 128026398

PTET:

122356438(tlr4al) 122356439 122356446

LROH:

127175170(tlr4bb) 127175171 127175172 127175174 127175175

OMC:	131552009 131552803

PPRM:

120479739(tlr4bb) 120479740 120479741

RKG:	130083093(tlr4bb) 130083094(tlr4al) 130083095

MAMB:

125276617 125276618(tlr4bb) 125276619

CIDE:

127525007 127525009 127525012

CERY:

137019969 137020384(tlr4bb) 137020385

MASI:

127412476

TROS:

130558706 130559273(tlr4bb) 130559437

TDW:	130431695(tlr4ba) 130431697(tlr4bb) 130431698

MANU:

129415784 129416215 129416621 129416700 129416861

IPU:

IFU:

PHYP:

SMEO:

TFD:	113639828 113639965

TVC:	132847218 132847219

TRN:

134315113

AMEX:

111195965 111196020 111196037

CMAO:

118810322 118810323 118810324

CHAR:

105911563

LOC:	102693850(tlr4)

PSPA:

121303579

ARUT:

117396808

PVUL:

126811810 126815029 126817967 126820929 126821986 126823795 126824198 126825316 126825358

GAE:	121367635 121369801 121370316

HRF:	124115484 124115485 124117461 124117468 124126783 124129306 124141456 124141459 124142299 124148630 124151810

HRJ:	124252808 124253891 124266916 124269410 124269429 124273048 124274128 124277510 124277520 124286564 124287212

CRG:	105324673 105324721 105336099 117681451 117681463 117683974

CANU:

128156319 128184366 128184562 128185905 128185907 128186340 128191248 128192641

CVN:	111102898 111103073 111112136 111112139 111118728 111119086 111128415

OED:	125649145 125667628 125675846 125682194 125682359

MYI:	110449935 110462584

PMAX:

117321101 117322243 117328236 117328500 117337974 117340338 117340468

MMER:

123529774 123542318

RPHI:

132733837 132738576 132739446

DPOL:

127839578 127844882 127845373 127845853 127860898

LJP:	135461939 135477097 135478155 135480245 135480384 135480637

LLON:

135485993 135486215 135486393 135490615

» show all

Reference

PMID:9237759

Authors

Medzhitov R, Preston-Hurlburt P, Janeway CA Jr

Title

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.

Journal

Nature 388:394-7 (1997)
DOI:10.1038/41131

Sequence

[hsa:7099]

Reference

PMID:17560196

Authors

Anand RJ, Kohler JW, Cavallo JA, Li J, Dubowski T, Hackam DJ

Title

Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis.

Journal

J Pediatr Surg 42:927-32; discussion 933 (2007)
DOI:10.1016/j.jpedsurg.2007.01.023

Sequence

[mmu:21898]

Reference

PMID:20711192

Authors

Schmidt M, Raghavan B, Muller V, Vogl T, Fejer G, Tchaptchet S, Keck S, Kalis C, Nielsen PJ, Galanos C, Roth J, Skerra A, Martin SF, Freudenberg MA, Goebeler M

Title

Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel.

Journal

Nat Immunol 11:814-9 (2010)
DOI:10.1038/ni.1919

Sequence

[hsa:7099]

All links

Ontology (5)   
   KEGG BRITE (5)   
Pathway (62)   
   KEGG PATHWAY (62)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (5)   
   KEGG DRUG (5)   
Gene (550)   
   KEGG GENES (441)   
   KEGG MGENES (77)   
   RefGene (25)   
   OC (7)   
Literature (3)   
   PubMed (3)   
All databases (626)   

Download RDF

ORTHOLOGY: K10159

Entry

K10159                      KO

Symbol

TLR2, CD282

Name

toll-like receptor 2

Pathway

map04145

Phagosome

map04151

PI3K-Akt signaling pathway

map04613

Neutrophil extracellular trap formation

map04620

Toll-like receptor signaling pathway

map05132

Salmonella infection

map05134

Legionellosis

map05140

Leishmaniasis

map05142

Chagas disease

map05144

Malaria

map05145

Toxoplasmosis

map05146

Amoebiasis

map05152

Tuberculosis

map05161

Hepatitis B

map05162

Measles

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05205

Proteoglycans in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05321

Inflammatory bowel disease

map05323

Rheumatoid arthritis

map05417

Lipid and atherosclerosis

Disease

H00342

Tuberculosis

H00344

Leprosy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K10159  TLR2, CD282; toll-like receptor 2
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K10159  TLR2, CD282; toll-like receptor 2
   04620 Toll-like receptor signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K10159  TLR2, CD282; toll-like receptor 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K10159  TLR2, CD282; toll-like receptor 2
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K10159  TLR2, CD282; toll-like receptor 2
   05161 Hepatitis B
    K10159  TLR2, CD282; toll-like receptor 2
   05171 Coronavirus disease - COVID-19
    K10159  TLR2, CD282; toll-like receptor 2
   05162 Measles
    K10159  TLR2, CD282; toll-like receptor 2
   05168 Herpes simplex virus 1 infection
    K10159  TLR2, CD282; toll-like receptor 2
   05169 Epstein-Barr virus infection
    K10159  TLR2, CD282; toll-like receptor 2
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K10159  TLR2, CD282; toll-like receptor 2
   05134 Legionellosis
    K10159  TLR2, CD282; toll-like receptor 2
   05152 Tuberculosis
    K10159  TLR2, CD282; toll-like receptor 2
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K10159  TLR2, CD282; toll-like receptor 2
   05144 Malaria
    K10159  TLR2, CD282; toll-like receptor 2
   05145 Toxoplasmosis
    K10159  TLR2, CD282; toll-like receptor 2
   05140 Leishmaniasis
    K10159  TLR2, CD282; toll-like receptor 2
   05142 Chagas disease
    K10159  TLR2, CD282; toll-like receptor 2
  09163 Immune disease
   05323 Rheumatoid arthritis
    K10159  TLR2, CD282; toll-like receptor 2
   05321 Inflammatory bowel disease
    K10159  TLR2, CD282; toll-like receptor 2
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K10159  TLR2, CD282; toll-like receptor 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K10159  TLR2, CD282; toll-like receptor 2
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K10159  TLR2, CD282; toll-like receptor 2
   04054 Pattern recognition receptors
    K10159  TLR2, CD282; toll-like receptor 2
   04090 CD molecules
    K10159  TLR2, CD282; toll-like receptor 2
   00536 Glycosaminoglycan binding proteins
    K10159  TLR2, CD282; toll-like receptor 2
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Toll-like receptors
    K10159  TLR2, CD282; toll-like receptor 2
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of breast milk
   K10159  TLR2, CD282; toll-like receptor 2
Pattern recognition receptors [BR:ko04054]
Membrane-bound pattern recognition receptors
  Toll-like receptors
   K10159  TLR2, CD282; toll-like receptor 2
CD molecules [BR:ko04090]
Proteins
  K10159  CD282, TLR2; toll-like receptor 2
Glycosaminoglycan binding proteins [BR:ko00536]
Hyaluronan
  Cell surface receptors
   K10159  TLR2, CD282; toll-like receptor 2

Genes

HSA:	7097(TLR2)

PTR:	471325(TLR2)

PPS:	100994768(TLR2)

GGO:	101128447(TLR2)

PON:	100456464(TLR2)

PPYG:

129035412(TLR2)

NLE:	100604724(TLR2)

HMH:	116465400(TLR2)

SSYN:

129481156(TLR2)

MCC:	574290(TLR2)

MCF:	102146068(TLR2)

MTHB:

126955690

MNI:	105463507(TLR2)

CSAB:

103236415

CATY:

105580685(TLR2)

PANU:

103884712(TLR2)

TGE:	112624698(TLR2)

MLEU:

105531455(TLR2)

RRO:	104677747(TLR2)

RBB:	108529041(TLR2)

TFN:

117086043

PTEH:

111553190(TLR2)

CANG:

105524473

CJC:	100404611(TLR2)

SBQ:	101045472(TLR2)

CIMI:

108282777

ANAN:

105714556(TLR2)

CSYR:

103274468(TLR2)

MMUR:

105881794(TLR2)

LCAT:

123638501(TLR2)

PCOQ:

105811134(TLR2)

OGA:	100964048(TLR2)

MMU:	24088(Tlr2)

MCAL:

110291353(Tlr2)

MPAH:

110320724(Tlr2)

RNO:	310553(Tlr2)

MCOC:

116093042(Tlr2)

ANU:	117707783(Tlr2)

MUN:	110541773(Tlr2)

CGE:	100771475(Tlr2)

MAUA:

101838156(Tlr2)

PROB:

127232768(Tlr2)

PLEU:

114710188(Tlr2)

MORG:

121452676(Tlr2)

MFOT:

126511616

AAMP:

119826466(Tlr2)

NGI:	103750991(Tlr2)

HGL:	101724657(Tlr2)

CPOC:

100717682(Tlr2)

CCAN:

109701180(Tlr2)

DORD:

105995883(Tlr2)

DSP:	122127146(Tlr2)

PLOP:

125341577(Tlr2)

NCAR:

124994917

MMMA:

107141269

OCU:	100009578(TLR2)

OPI:	101523730(TLR2)

TUP:	102482498(TLR2)

CFA:	448807(TLR2)

CLUD:

112654591(TLR2)

VVP:	112933419(TLR2)

VLG:	121480909(TLR2)

NPO:	129516767(TLR2)

AML:	100465129(TLR2)

UMR:

103658031

UAH:	113255769(TLR2)

UAR:	123793207(TLR2)

ELK:

111154734

LLV:

125093126

MPUF:

101681595(TLR2)

MNP:	132000985(TLR2)

MLK:	131831467(TLR2)

NVS:	122889469(TLR2)

ORO:	101363280(TLR2) 101367407

EJU:	114210089(TLR2)

ZCA:	113925471(TLR2)

MLX:	118022230(TLR2) 118022538

NSU:	110588386 110588474(TLR2)

LWW:	102737828(TLR2)

FCA:	493797(TLR2)

PYU:	121026443 121026463

PCOO:

112858853

PBG:	122475284(TLR2)

PVIV:

125163954(TLR2)

LRUF:

124520186

PTG:	102962241 102964242

PPAD:

109262509(TLR2)

PUC:

125923764

AJU:

106982476

HHV:	120233209(TLR2)

BTA:	281534(TLR2)

BOM:	102268835(TLR2)

BIU:	109571498(TLR2)

BBUB:

102397791(TLR2)

BBIS:

104989153(TLR2)

CHX:	100860747(TLR2)

OAS:	554262(TLR2)

BTAX:

128062410(TLR2)

ODA:	120871484(TLR2)

CCAD:

122451361(TLR2)

MBEZ:

129542442(TLR2)

SSC:	396623(TLR2)

CFR:	102523960(TLR2)

CBAI:

105079727(TLR2)

CDK:	105099662(TLR2)

VPC:	102525227(TLR2)

BACU:

102998386(TLR2)

BMUS:

118896009(TLR2)

LVE:

103090179

OOR:	101276053(TLR2)

DLE:	111187714(TLR2)

PCAD:

102976342(TLR2)

PSIU:

116754202(TLR2)

NASI:

112407985(TLR2)

ECB:	100009701(TLR2)

EPZ:	103553736(TLR2)

EAI:	106821799(TLR2)

MYB:	102256005(TLR2)

MYD:	102761137(TLR2)

MMYO:

118658736(TLR2)

MLF:	102424442(TLR2)

MDT:	132235454(TLR2)

PKL:	118711134(TLR2)

EFUS:

103288450(TLR2)

MNA:	107525584(TLR2)

DRO:	112312607(TLR2)

SHON:

118995387(TLR2)

AJM:	119065905(TLR2)

PDIC:

114503036(TLR2)

PHAS:

123813727(TLR2)

MMF:	118616119(TLR2)

PPAM:

129061625(TLR2)

HAI:	109382017(TLR2)

RFQ:	117037546(TLR2)

PALE:

102893057(TLR2)

PGIG:

120613273(TLR2)

PVP:	105291526(TLR2)

RAY:	107510758(TLR2)

MJV:	108390634(TLR2)

TOD:	119233466(TLR2)

SARA:

101542483(TLR2)

SETR:

126003414(TLR2)

LAV:	100654442(TLR2)

TMU:

101342847

ETF:	101643417(TLR2)

DNM:	101421345(TLR2)

MDO:	100024558(TLR2)

GAS:	123251496(TLR2)

SHR:	100932981(TLR2)

AFZ:

127540467

PCW:	110213633(TLR2)

TVP:	118854154(TLR2)

OAA:	100081248(TLR2)

GGA:	374141(TLR2A) 769014(TLR2B)

MGP:	104910743 109363679 109363685

CJO:	107313061 107313069

TPAI:

128084363(TLR2) 128084365

LMUT:

125691799 125691800(TLR2)

NMEL:

110398324(TLR2)

APLA:

101791786(TLR2) 110351185

ACYG:

106032265 106032266

CATA:

118249208 118249271(TLR2)

AFUL:

116488900 116488978(TLR2)

TGU:	100219691(TLR2)

SCAN:

103826229(TLR2)

PMOA:

120497936 120497937

OTC:	121331387 121331388

PRUF:

121360328 121360373

GFR:	102036739 102045171

FAB:	101811742 101811943(TLR2)

OMA:	130252788 130252789(TLR2)

PHI:	102104379 102104560(TLR2)

PMAJ:

107202976(TLR2)

CCAE:

111927833 111927834

CCW:	104697168(TLR2) 120409612

CBRC:

103617360 103617361

ETL:	114066323(TLR2)

ZAB:	102063127(TLR2)

ZLE:	135446672 135447324(TLR2)

ACHL:

103806228 103811860

SVG:	106861726(TLR2)

MMEA:

130579325(TLR2)

HRT:	120752902 120753504

SATI:

136360438(TLR2) 136360439

FPG:	101923386(TLR2) 101923563

FCH:	102051584(TLR2)

NNT:	104401150(TLR2)

SHAB:

115610854(TLR2) 115610981

ACUN:

113479805 113479806(TLR2)

TALA:

116965176(TLR2)

ACHC:

115339865 115339882(TLR2)

HLE:	104827771 104843273

AGEN:

126044629 126044630

GCL:	127015580 127015793

CSTI:

104562380

LDI:

104345532

MNB:	103768149 103772535

DPUB:

104298307(TLR2) 104298317

AVIT:

104275874 104280221(TLR2)

BRHI:

104495472

EGZ:	104126737 104126791(TLR2)

NNI:	104008501 104021229(TLR2) 104021230

PCRI:

PCAO:

PADL:

AFOR:

FGA:	104069477 104077048

CLV:	102084454 102084767(TLR2)

MUI:	104536714 104542596

EHS:	104502684(TLR2)

CMAC:

104473065(TLR2)

CUCA:

104054217(TLR2)

TEO:	104376160 104379432(TLR2)

BREG:

OHA:

ACAR:

CPEA:

CVF:	104293775 104294126 104294127

RTD:	128910481 128910566(TLR2)

AAM:	106491872 106491913

AROW:

112967647 112976729 112976730

NPD:	112949303(TLR2)

TGT:	104566013(TLR2)

DNE:	112985951 112985953(TLR2)

SCAM:

104145540 104145542

ASN:	102368109(TLR2) 102368346 102383734 102384063

AMJ:	102571171(CD14) 102572093(TLR2) 106740518(TLR2)

CPOO:

109309593(TLR2) 109309681

GGN:	109300368 109300828(TLR2)

PSS:	102445063 102457158(TLR2) 102457570 102458059

CMY:	102934124 102943966 102944187

CCAY:

125625972 125635718 125635747

DCC:	119847754 119855141 119855269

CPIC:

101932351(TLR2) 101932616 101937770 101939272

TST:	117869678 117878440 117878538

CABI:

116824075 116824076(TLR2) 116831845

MRV:	120390761 120406276(TLR2) 120407011

ACS:	100564001(tlr2) 100564196 100564690 103278612 103278613(cd14)

ASAO:

132776793 132776794 132776795

PVT:	110069865 110072767(TLR2) 110082123

SUND:

121930303 121931996

PBI:	103049109 103064827(TLR2)

PMUR:

107283615(CD14) 107288063 107289574(TLR2)

CTIG:

120309597(TLR2) 120314888

TSR:	106544777(TLR2) 106553961

PGUT:

117662113(TLR2) 117671348

APRI:

131203177(TLR2)

PTEX:

113435841(TLR2)

NSS:	113417952(TLR2)

VKO:	123023851(TLR2)

PMUA:

114586776 114601154(CD14)

PRAF:

128421069(TLR2)

ZVI:	118076498 118079342(CD14) 118084395(TLR2)

HCG:	128328284(TLR2)

GJA:	107107978 107108593(TLR2) 107119739

STOW:

125439146 125439571(TLR2)

EMC:	129337116(TLR2)

XLA:	108699311 108699322 108699606 108700404 108706656 108710847

XTR:	100485512 100485771(tlr2) 100485927 100487973 116409470

NPR:	108788197(TLR2) 108791424 108795015

RTEM:

120920062(TLR2) 120932459(CD14)

BBUF:

120990049(TLR2) 121008994

BGAR:

122926450 122942595(TLR2)

MUO:

115476667

GSH:	117351709 117358950(TLR2)

DRE:	403125(tlr2) 403133(tlr18)

SRX:	107717772 107722930

SANH:

107663243 107689857 107702532(tlr2)

SGH:	107590711 107597981

CCAR:

109060541 109073772 109074587

CAUA:

113059585 113093059 113116771

CGIB:

127948925 127974955 127985733 128030704

PTET:

122346867(tlr2) 122360297(tlr18)

LROH:

127151788(tlr2) 127178597(tlr18)

OMC:	131521342(tlr18) 131549258(tlr2)

PPRM:

120463819(tlr2) 120484621(tlr18)

RKG:	130069309(tlr18) 130096862(tlr2)

MAMB:

125243183(tlr18) 125272716(tlr2)

CIDE:

127496769 127525683

CERY:

137032534(tlr2) 137034439(tlr18)

MASI:

127443498 127445422 127453406

TROS:

130552481(tlr2) 130557525(tlr18)

TDW:	130410141(tlr2) 130432366(tlr18)

MANU:

129444970(tlr2) 129448122(tlr18)

IPU:	108258959 108272691(tlr18)

IFU:	128601965(tlr2) 128610284(tlr18)

PHYP:

113533829 113535686(tlr2)

SMEO:

124378063(tlr2) 124384137(tlr18)

TFD:	113640381(tlr2) 113644773(tlr18)

TVC:	132839182(tlr2) 132845889(tlr18)

TRN:	134310788(tlr18) 134328550(tlr2)

AMEX:

103042489(tlr18) 103044794(tlr2) 103045101

CMAO:

118802154 118802155(tlr2) 118813108(tlr18)

EEE:	113583650 113589619

CHAR:

105891725(tlr18) 105903891(tlr2)

TRU:	101068527 101068557(tlr2)

TFS:	130522399(tlr2) 130532143(tlr18)

TNG:	GSTEN00004567G001

LCO:	104923941 104934739 104938453

NCC:

104943968

TBEN:

117469881 117481585 117494857(tlr18)

CGOB:

115009776(tlr2) 115014553 115020848

PGEO:

117447943 117460761 117463567

GACU:

117553624 117556193 117563201(tlr18)

EMAC:

134861669(tlr18) 134864416 134876155

ELY:	117246200 117254631 117265722(tlr18)

EFO:	125883414 125886267 125892600(tlr18)

PLEP:

121940407 121941713 121946307(tlr18) 121962081

SLUC:

116049085(tlr18) 116051764 116052112

ECRA:

117945977(tlr18) 117962114

ESP:	116690715 116690724(tlr2)

PFLV:

114545526 114556771 114562422 114562886(tlr2)

GAT:	120811005(tlr18) 120822770(tlr2)

PPUG:

119197595(tlr18) 119222892(tlr2)

AFB:	129093095 129095397 129109086(tlr18)

CLUM:

117745125(tlr18) 117746792 117747505

PSWI:

130187916(tlr18)

MSAM:

119898091(tlr18) 119898773 119913078

SCHU:

122870109 122874079 122880368 122881275(tlr18)

CUD:	121504107 121504364 121504365 121504758 121504890 121507773 121507774 121507775 121507776 121507777 121507831 121513395(tlr18) 121515920

ALAT:

119005747(tlr18) 119007510 119020799 119027456

MZE:	101463793 101470585 101484533 106675443 106675704

ONL:	100694547(tlr2) 100705953 102076284 102076916(tlr2) 102077009 109202487

OAU:	116312407 116312408 116317422 116333491(tlr18)

OLA:	101155381 101162959 101173259

OML:	112136553(tlr18) 112155905 112156495

CSAI:

133420343 133420381 133420940 133420954 133440663(tlr18)

XMA:	102226787 102227045 102230797

XCO:	114140250 114157991 114158033

XHE:	116717639 116732043 116732869

PRET:

103460805(tlr2) 103477637 103480941

PFOR:

103149044(tlr2) 103155238

PLAI:

106947305 106947306 106959996

PMEI:

106920377 106924268(tlr2)

GAF:	122820936 122820938 122830836(tlr18)

PPRL:

129351429 129370861(tlr18) 129376764

CVG:	107082271(tlr2) 107082292 107084756

CTUL:

119781865(tlr18) 119797978 119797979

GMU:	124865385(tlr18) 124880508 124880509 124880848

NFU:	107379226 107395103

KMR:	108239773 108243184(tlr18) 108248293(tlr2)

ALIM:

106526902 106529226

NWH:	119409653(tlr18) 119417310(tlr2)

AOCE:

111571645 111586854(tlr2)

MCEP:

125003751 125008678(tlr2) 125017001(tlr18) 125023802

CSEM:

103388693

POV:	109633418 109646959(tlr2)

SSEN:

122766853(tlr2) 122774672(tlr18)

HHIP:

117770129 117776644(tlr18) 117779093

HSP:	118102678(tlr2) 118114297(tlr18)

PPLT:

128430232 128436925 128449156(tlr18)

SMAU:

118283876(tlr2) 118285011(tlr18) 118312269

LCF:	108883170(tlr18) 108885865 108901668 108902352

SDU:	111216599(tlr2) 111222405 111236680 111240019

SLAL:

111668167 111669232

XGL:	120784198(tlr18) 120797238(tlr2)

HCQ:

109512204

SSCV:

125975209

SBIA:

133500323(tlr18)

PEE:	133401555(tlr18)

PTAO:

133479423(tlr18)

BPEC:

110160272 110170449

MALB:

109968926

BSPL:

114843048(tlr18) 114851239(tlr2)

SJO:	128366894(tlr18) 128379964 128384059

SASA:

106580799 106605325 106608430

STRU:

115176782 115178865 115198035

OTW:	112229323(tlr18) 112237807(tlr2)

OMY:	100750259(tlr2) 110487251(tlr18) 110514733

OGO:	123997036 124005693 124013924(tlr2)

ONE:	115103983 115141066

OKI:	109882984 109901726 109903645

OKE:	118364051 118367486(tlr18) 118377787(tlr2)

SALP:

111965103 112076105

SNH:	120031357 120041431 120048414

CCLU:

121543120 121571065

ELS:	105028681 105030906(tlr2)

SFM:

108926796

PKI:

111838449

AANG:

118229631(tlr18) 118231932 118231933

LOC:	102687114 107077084(tlr2)

PSPA:

121309885(tlr18) 121327847(tlr2) 121331267

ARUT:

117395620 117408874 117413139 117416631 117965134

PSEX:

120527440(tlr18)

LCM:	102350366 102355189 102367073(TLR2)

CMK:	103185476 103185499

RTP:	109912800 109928617

CPLA:

122554467 122554772(tlr2)

HOC:	132818507 132819313 132819394

LERI:

129701139(prg4b) 129702580(tlr2)

PMRN:

116938861 116938862 116957696

LRJ:	133345800 133345801 133345803

HAME:

PPOI:

DSV:

CSCU:

CVS:

PVUL:

126823654 126823656 126825506

HRF:	124110340 124111012 124111015 124126792 124132656 124134791 124151809 124151813 124152451

HRJ:	124269430 124269469 124269852 124286645 124289089

CRG:

117692251

CANU:

128164706 128173514 128177291 128182770 128182789 128183906 128183995 128184388 128184588 128184918 128185946

CVN:	111102496 111104187 111104188 111108808 111112133 111112140 111112158 111114417 111114419

OED:	125664252 125664253 130046322 130047628 130047630

PMAX:

117320158 117320159 117322517 117322518 117325711 117330866 117340547 117343932 117343980 117344055

MMER:

123556839 123563464

RPHI:

132714864 132720377 132744805

DPOL:

127845372 127859167

MAEA:

128234139 128234764 128240582 128240583

LJP:	135479508 135479758

AMIL:

114952281

PDAM:

113685912

» show all

Reference

PMID:9596645

Authors

Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS

Title

Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

Journal

Blood 91:4020-7 (1998)

Sequence

[hsa:7097]

Reference

PMID:19931471

Authors

Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, Han SH, Lee H, Paik SG, Lee JO

Title

Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.

Journal

Immunity 31:873-84 (2009)
DOI:10.1016/j.immuni.2009.09.018

Sequence

[mmu:24088]

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