KEGG   ORTHOLOGY: K10713Help
Entry
K10713                      KO                                     

Name
fae
Definition
5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K10713  fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.147  5,6,7,8-tetrahydromethanopterin hydro-lyase
     K10713  fae; 5,6,7,8-tetrahydromethanopterin hydro-lyase
BRITE hierarchy
Other DBs
RN: R08058
COG: COG1795
Genes
KMI: VW41_19435
CNT: JT31_16265
CEM: LH23_01445
CEN: LH86_01435
YPE: YPO2460
YPK: y1729
YPH: YPC_1667
YPA: YPA_1958
YPN: YPN_2056
YPM: YP_2279
YPZ: YPZ3_2110
YPD: YPD4_2151
YPX: YPD8_2236
YPW: CH59_2(fae)
YPJ: CH55_148(fae)
YPV: BZ15_1068(fae)
YPL: CH46_2648(fae)
YPS: YPTB2503
YPO: BZ17_4134(fae)
YPY: YPK_1651
YPB: YPTS_2597
YPQ: DJ40_4039(fae)
YPU: BZ21_1799(fae)
YPR: BZ20_3706(fae)
YPC: BZ23_2084(fae)
YPF: BZ19_1865(fae)
SPE: Spro_2468
DYE: EO087_01975(fae)
PCQ: PcP3B5_53090(fae)
PMAN: OU5_6013
PSEM: TO66_12085
PSOS: POS17_3724
PANR: A7J50_2664
MCA: MCA2866
METL: U737_11025(fae) U737_14805(fae)
MAH: MEALZ_0850(fae2) MEALZ_2428(fae)
MPSY: CEK71_02655(fae)
MEJ: Q7A_47(fae)
MEC: Q7C_1775
NHL: Nhal_3879
NWR: E3U44_04660(fae)
AMAH: DLM_3633
RIN: ACS15_3974(fae)
BCEN: DM39_4730(fae)
BMK: DM80_4395(fae)
BTEI: WS51_00910
BXE: Bxe_B2436(fae)
BXB: DR64_4764(fae)
BPH: Bphy_6487
BFN: OI25_5387(fae)
PARB: CJU94_31180(fae)
PHS: C2L64_32370(fae) C2L64_38280(fae)
PTER: C2L65_29025(fae) C2L65_34275(fae)
PGP: CUJ91_21485(fae) CUJ91_30315(fae)
PCJ: CUJ87_23435(fae) CUJ87_27745(fae)
PTS: CUJ90_28055(fae)
VPD: VAPA_1c31430(fae)
MPT: Mpe_A2612
METP: C1M51_15080(fae)
CARE: LT85_1433
LCH: Lcho_3147
RGE: RGE_40280(fae)
METR: BSY238_3289(fae)
MFA: Mfla_1652
AZA: AZKH_p0270(fae)
AZD: CDA09_11330(fae)
THK: CCZ27_13240(fae)
MESM: EJ066_29735(fae)
RGA: RGR602_PC01571(fae)
AZC: AZC_0890
SNO: Snov_1050
MEX: Mext_1834
MEA: Mex_1p1766(fae)
MDI: METDI2518(fae)
MCH: Mchl_2169
MPO: Mpop_1785
MET: M446_5783
MNO: Mnod_6007
MOR: MOC_0688
META: Y590_08785
MAQU: Maq22A_c16490(fae)
MEE: DA075_05745(fae)
METD: C0214_10540(fae)
METS: DK389_20670(fae)
METI: DK427_18460(fae)
MSL: Msil_2390
MLG: CWB41_06060(fae) CWB41_07900(fae)
HDN: Hden_1474
HMC: HYPMC_1624(fae)
FIL: BN1229_v1_0583(fae)
FIY: BN1229_v1_0585(fae)
MSC: BN69_1051(fae) BN69_1356(fae) BN69_1357
MROS: EHO51_11440(fae) EHO51_13070(fae) EHO51_13075(fae)
MTW: CQW49_13475(fae) CQW49_13480(fae)
MCG: GL4_1783
HDI: HDIA_2315(fae_2)
ALI: AZOLI_p10696(fae1) AZOLI_p10886(fae2)
ABS: AZOBR_p270080(fae)
AZT: TSH58p_01220(fae)
AZM: DM194_17130(fae)
SMAL: SMALA_7629
LTR: EVS81_09120(fae)
ARN: CGK93_03385(fae)
AAU: AAur_0648
AMD: AMED_6210
AMN: RAM_31860
AMM: AMES_6120
AMZ: B737_6120
RBA: RB10297(fae)
PIR: VN12_18235(fae_2)
PLM: Plim_1285
PLS: VT03_31915(fae_2)
PLH: VT85_19960(fae_2)
FMR: Fuma_01647(fae_1)
GES: VT84_01760(fae_1)
GOG: C1280_25120(fae)
IPA: Isop_1013
SACI: Sinac_4954
PBOR: BSF38_04915(fae_2)
MOX: DAMO_0454(fae)
METH: MBMB1_1667
MKA: MK1275
GAH: GAH_00673
MAC: MA_3006
MBAR: MSBR2_2410
MBAK: MSBR3_2463
MTHE: MSTHC_0717
MFZ: AOB57_002495(fae)
MBU: Mbur_0367
MMET: MCMEM_1329
MCJ: MCON_1033(faeA)
MHI: Mhar_0339
MEMA: MMAB1_2454(faeA)
RCI: RCIX1876(fae)
IAG: Igag_0274
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Vorholt JA, Marx CJ, Lidstrom ME, Thauer RK
  Title
Novel formaldehyde-activating enzyme in Methylobacterium extorquens AM1 required for growth on methanol.
  Journal
J Bacteriol 182:6645-50 (2000)
DOI:10.1128/JB.182.23.6645-6650.2000
  Sequence
Reference
  Authors
Goenrich M, Thauer RK, Yurimoto H, Kato N
  Title
Formaldehyde activating enzyme (Fae) and hexulose-6-phosphate synthase (Hps) in Methanosarcina barkeri: a possible function in ribose-5-phosphate biosynthesis.
  Journal
Arch Microbiol 184:41-8 (2005)
DOI:10.1007/s00203-005-0008-1

KEGG   ORTHOLOGY: K13812Help
Entry
K13812                      KO                                     

Name
fae-hps
Definition
bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
Pathway
ko00030  Pentose phosphate pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
ko01230  Biosynthesis of amino acids
Module
M00345  Formaldehyde assimilation, ribulose monophosphate pathway
M00580  Pentose phosphate pathway, archaea, fructose 6P => ribose 5P
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00030 Pentose phosphate pathway
    K13812  fae-hps; bifunctional enzyme Fae/Hps
  09102 Energy metabolism
   00680 Methane metabolism
    K13812  fae-hps; bifunctional enzyme Fae/Hps
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.43  3-hexulose-6-phosphate synthase
     K13812  fae-hps; bifunctional enzyme Fae/Hps
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.147  5,6,7,8-tetrahydromethanopterin hydro-lyase
     K13812  fae-hps; bifunctional enzyme Fae/Hps
BRITE hierarchy
Other DBs
RN: R05338 R08058
COG: COG1795 COG0269
Genes
MJA: MJ_1447
MFE: Mefer_1012
MVU: Metvu_1176
MFS: MFS40622_0906
MIF: Metin_1286
MJH: JH146_0570
MIG: Metig_0664
MAE: Maeo_0614
MOK: Metok_1249
MTH: MTH_1474
MMG: MTBMA_c00570(fae_hps)
METC: MTCT_1339
MWO: MWSIV6_0011(fae-hps)
METE: tca_01421(fae)
MST: Msp_1498
MSI: Msm_1213
MRU: mru_2131
MEB: Abm4_0046
MMIL: sm9_0074
MEYE: TL18_10355
MOL: YLM1_1686
METH: MBMB1_0009(fae-hps)
MFC: BRM9_0060
MFI: DSM1535_1378(fae-hps)
MCUB: MCBB_0021(fae-hps_1)
METT: CIT01_05685(fae)
METO: CIT02_07030(fae)
MFV: Mfer_0572
AFU: AF_1305
FPL: Ferp_2129
GAC: GACE_2158
GAH: GAH_00575
MAC: MA_4608
MBAR: MSBR2_2313
MBAK: MSBR3_2375
MMA: MM_1279
MMAC: MSMAC_0037
METM: MSMTP_0040
MTHE: MSTHC_1499
MTHR: MSTHT_1787
MHOR: MSHOH_0037
MBU: Mbur_1994(fae-hps)
MMET: MCMEM_0222
MMH: Mmah_0234
MPY: Mpsy_1425
MTP: Mthe_0988
MCJ: MCON_1383
MHI: Mhar_0019
MHU: Mhun_1628
MLA: Mlab_0996
MEMA: MMAB1_1386(fae-hps)
MPI: Mpet_0801
MBN: Mboo_0772
MPL: Mpal_1036
MPD: MCP_2904(fae_hps)
MEZ: Mtc_0381(fae)
RCI: RCIX775(fae-hps)
BARC: AOA65_1083(faeB-hpsB)
BARB: AOA66_1278
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grochowski LL, Xu H, White RH
  Title
Ribose-5-phosphate biosynthesis in Methanocaldococcus jannaschii occurs in the absence of a pentose-phosphate pathway.
  Journal
J Bacteriol 187:7382-9 (2005)
DOI:10.1128/JB.187.21.7382-7389.2005
  Sequence
[mja:MJ_1447]

KEGG   REACTION: R08058Help
Entry
R08058                      Reaction                               

Name
5,6,7,8-tetrahydromethanopterin hydro-lyase (formaldehyde-adding, 5,10-methylenetetrahydromethanopterin-forming)
Definition
5,6,7,8-Tetrahydromethanopterin + Formaldehyde <=> 5,10-Methylenetetrahydromethanopterin + H2O
Equation
Reaction class
RC01583  C01217_C04377
RC01795  C00067_C04377
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Orthology
K10713  5,6,7,8-tetrahydromethanopterin hydro-lyase [EC:4.2.1.147]
K13812  bifunctional enzyme Fae/Hps [EC:4.2.1.147 4.1.2.43]
Other DBs
RHEA: 24681

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