KEGG ORTHOLOGY: K10771

ORTHOLOGY: K10771

Entry

K10771                      KO

Symbol

APEX1

Name

AP endonuclease 1 [EC:3.1.11.2]

Pathway

map03410

Base excision repair

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    K10771  APEX1; AP endonuclease 1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10771  APEX1; AP endonuclease 1
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     K10771  APEX1; AP endonuclease 1
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     K10771  APEX1; AP endonuclease 1

Other DBs

GO:	0008296 0052720

Genes

HSA:	328(APEX1)

PTR:	465200(APEX1)

PPS:	100987860(APEX1)

GGO:	101131302(APEX1)

PON:	134760036(APEX1)

PPYG:

129012580(APEX1)

NLE:	100592412(APEX1)

HMH:	116484591(APEX1)

SSYN:

129487974(APEX1)

MCC:	702757(APEX1)

MCF:	101926821(APEX1)

MTHB:

126958291

MNI:	105499194(APEX1)

CSAB:

103231340 103231343

CATY:

105593940(APEX1)

PANU:

101000737(APEX1)

TGE:	112629449(APEX1)

MLEU:

105536723(APEX1)

RRO:	104659208 104673147(APEX1)

RBB:	108527309(APEX1)

TFN:	117070089(APEX1)

PTEH:

111522533(APEX1)

CANG:

105523150(APEX1)

CJC:	100400557(APEX1)

SBQ:	101053887(APEX1)

CIMI:

108311931(APEX1)

ANAN:

105726327(APEX1)

CSYR:

103250419(APEX1)

MMUR:

105864728(APEX1)

LCAT:

123621503(APEX1)

PCOQ:

105814399(APEX1)

OGA:	100963013(APEX1)

MMU:	11792(Apex1)

MCAL:

110309328(Apex1)

MPAH:

110325347(Apex1)

RNO:	79116(Apex1)

MCOC:

116084316(Apex1)

ANU:	117705196(Apex1)

MUN:	110549702(Apex1)

CGE:	100689281(Apex1)

MAUA:

101834958(Apex1)

PROB:

127216189(Apex1)

PLEU:

114696011(Apex1)

MORG:

121438587(Apex1)

MFOT:

126492850

AAMP:

119800362(Apex1) 119801151

NGI:	103724467 103733668(Apex1)

HGL:	101709711(Apex1)

CPOC:

100719062(Apex1)

CCAN:

109692127(Apex1)

DORD:

106000446(Apex1)

DSP:	122126585(Apex1)

PLOP:

125358521(Apex1)

NCAR:

124976818

MMMA:

107138265(Apex1) 107150834

OCU:

100348924

OPI:	101528788(APEX1)

TUP:	102474769(APEX1)

GVR:	103605042(APEX1)

CFA:	482558(APEX1)

CLUD:

112654417(APEX1) 125752830

VVP:	112914843(APEX1)

VLG:	121481489(APEX1)

NPO:	129520679(APEX1)

AML:	100482041(APEX1)

UMR:	103656308(APEX1)

UAH:	113248961(APEX1)

UAR:	123783908(APEX1)

ELK:

111162273

LLV:	125086686 125103916

MPUF:

101692778

MNP:	131999589(APEX1) 132003535 132026055

MLK:	131814688 131815621 131836034(APEX1)

NVS:	122893350(APEX1)

ORO:	101373404(APEX1)

EJU:	114221364(APEX1)

ZCA:	113908837(APEX1)

MLX:	118002963(APEX1)

NSU:	110585482(APEX1)

LWW:	102750699(APEX1)

FCA:	101101318(APEX1)

PYU:	121031401(APEX1)

PCOO:

112856466(APEX1)

PBG:	122467672(APEX1)

PVIV:

125168343(APEX1)

LRUF:

124508752

PTG:	102956501(APEX1)

PPAD:

109255758(APEX1)

PUC:

125909746

AJU:

106971401

HHV:	120225954(APEX1)

BTA:	281630(APEX1)

BOM:	102268633(APEX1)

BIU:	109564877(APEX1)

BBUB:

102414395(APEX1)

BBIS:

104988203(APEX1)

CHX:	100860967(APEX1)

OAS:	101115462(APEX1) 101117300

BTAX:

128053789(APEX1) 128055427

ODA:	120853334(APEX1)

CCAD:

122443314(APEX1) 122447257 122453626

MBEZ:

129563107(APEX1)

SSC:	100154728(APEX1)

CFR:	102521040(APEX1)

CBAI:

105064675(APEX1)

CDK:	105097645(APEX1)

VPC:	102540867(APEX1)

BACU:

103012226(APEX1)

BMUS:

118890180(APEX1)

LVE:	103083611(APEX1)

OOR:	101273638(APEX1)

DLE:	111181806(APEX1)

PCAD:

102982322(APEX1)

PSIU:

116749942(APEX1)

NASI:

112410598(APEX1)

ECB:	100072588(APEX1)

EPZ:	103559538(APEX1)

EAI:	106833285(APEX1)

MYB:	102251410(APEX1)

MYD:	102771397(APEX1)

MMYO:

118649141(APEX1)

MLF:	102423369(APEX1)

MDT:	132239532(APEX1)

PKL:	118724251(APEX1)

EFUS:

103303502(APEX1)

MNA:	107526960(APEX1)

DRO:	112311618(APEX1)

SHON:

118982615(APEX1) 118986948

AJM:	119036602(APEX1)

PDIC:

114490309(APEX1)

PHAS:

123808164(APEX1)

MMF:	118641624(APEX1)

PPAM:

129064395(APEX1)

HAI:	109376448(APEX1)

RFQ:	117023445(APEX1)

PALE:

102897846(APEX1)

PGIG:

120608056(APEX1)

PVP:	105308944(APEX1)

RAY:	107521159(APEX1)

MJV:	108403279(APEX1)

TOD:	119238853(APEX1)

SARA:

101537646(APEX1) 101556238

SETR:

126001383(APEX1)

LAV:	100661299(APEX1)

TMU:

101357524

ETF:	101650609(APEX1) 101651290

DNM:	101420999(APEX1)

MDO:	100029539(APEX1)

GAS:	123238009(APEX1)

SHR:	100924341(APEX1)

AFZ:

127549142

PCW:	110217507(APEX1)

TVP:	118830311(APEX1)

OAA:	100086075(APEX1)

GGA:

112531093

PCOC:

116241721(APEX1)

MGP:	104915812(APEX1)

CJO:	107307005(APEX1)

LMUT:

125686207(APEX1)

LSR:	110481134(APEX1)

SCAN:

103824983(APEX1)

PMOA:

120511642

OTC:	121342962(APEX1)

PRUF:

121352093(APEX1)

GFR:	102043442(APEX1)

OMA:	130262811(APEX1)

PHI:	102100942(APEX1)

PMAJ:

107199088(APEX1)

ZLE:	135460670(APEX1)

SVG:	106864466(APEX1)

MMEA:

130587492(APEX1)

HRT:	120748028(APEX1)

AGEN:

126036917

CVF:	104290378(APEX1)

RTD:	128901866(APEX1)

AROW:

112965165

ASN:	102369182(APEX1)

AMJ:	102560012(APEX1)

CPOO:

109320504(APEX1)

GGN:	109294769(APEX1)

CMY:	102941002(APEX1)

CCAY:

125621963(APEX1)

DCC:	119842131(APEX1)

CPIC:

101946358(APEX1)

TST:	117885342(APEX1)

CABI:

116816460(APEX1)

MRV:	120380994(APEX1)

ACS:	100554177(apex1)

ASAO:

132777716(APEX1)

PVT:	110089557 110089565(APEX1)

SUND:

121935025(APEX1)

PBI:	103049845(APEX1)

PMUR:

107292315(APEX1)

CTIG:

120311015(APEX1)

TSR:	106549931(APEX1)

PGUT:

117662189(APEX1)

APRI:

131197257(APEX1)

PTEX:

113449575(APEX1)

NSS:	113425317(APEX1)

VKO:	123019495(APEX1)

PMUA:

114581601(APEX1)

PRAF:

128401022(APEX1)

ZVI:	118095025(APEX1)

HCG:	128330291(APEX1)

GJA:	107116172(APEX1)

STOW:

125445184(APEX1)

EMC:	129338175(APEX1)

XLA:	108707047(apex1.S) 432324(apex1.L)

XTR:	394929(apex1)

NPR:	108788727(APEX1) 108794448

RTEM:

120940073(APEX1)

BBUF:

120988954(APEX1)

BGAR:

122924118(APEX1)

MUO:	115457745(APEX1)

GSH:	117350692(APEX1)

DRE:	406730(apex1) 558198(si:ch211-141o9.10)

SRX:	107725930 107736388

SANH:

107656416 107658891 107690061

SGH:	107579619 107583973 107584211

CCAR:

109063785

CAUA:

113048533 113048534 113058194 113059822 113111730

CGIB:

127956617 127969390(si:ch211-141o9.10) 127978039

PTET:

122342484(apex1) 122355168(si:ch211-141o9.10)

LROH:

127164610(apex1) 127173930(si:ch211-141o9.10)

OMC:	131539079(apex1) 131551265(si:ch211-141o9.10)

PPRM:

120476641(apex1) 120488694(si:ch211-141o9.10)

RKG:	130079969(apex1) 130088600(si:ch211-141o9.10)

MAMB:

125244646(apex1) 125255057(si:ch211-141o9.10)

CIDE:

127511361 127524029(si:ch211-141o9.10)

CERY:

137008192(si:ch211-141o9.10) 137023786(apex1)

MASI:

127423461(si:ch211-141o9.10) 127426828 127434874 127436410

TROS:

130547952(apex1) 130568856(si:ch211-141o9.10)

TDW:	130421081(apex1) 130438759(si:ch211-141o9.10)

MANU:

129420303(si:ch211-141o9.10) 129431829(apex1)

IPU:	108273827(si:ch211-141o9.10) 108279796

IFU:	128616879(si:ch211-141o9.10) 128623103(apex1)

PHYP:

113527071 113532296(apex1)

SMEO:

124388653(si:ch211-141o9.10) 124401907(apex1)

TFD:	113637129(si:ch211-141o9.10) 113647248(apex1)

TVC:	132839097(si:ch211-141o9.10) 132858647(apex1)

TRN:	134321943(si:ch211-141o9.10) 134323183(apex1)

AMEX:

103025298(si:ch211-141o9.10) 103034265(apex1)

CMAO:

118800243(si:ch211-141o9.10) 118812207(apex1)

EEE:	113574810 113575363(apex1)

CHAR:

105888825(si:ch211-141o9.10) 122129928(apex1)

TRU:	101069391(apex1) 105416569

TFS:	130518935(apex1) 130524089(si:ch211-141o9.10)

TNG:	GSTEN00010570G001 GSTEN00024229G001

LCO:	104918894 104922656(apex1)

NCC:	104946826(apex1)

TBEN:

117484942(apex1)

CGOB:

115024740 115028138(apex1)

PGEO:

117468395(apex1)

GACU:

117552480(apex1)

EMAC:

134878991(apex1)

ELY:	117246859(si:ch211-141o9.10) 117249358(apex1)

EFO:	125880476(si:ch211-141o9.10) 125882958(apex1)

PLEP:

121958450(si:ch211-141o9.10) 121961211(apex1)

SLUC:

116048756(si:ch211-141o9.10) 116054553(apex1)

ECRA:

117936485(si:ch211-141o9.10) 117938591(apex1)

ESP:	116670845 116673426(apex1)

PFLV:

114547625 114550120(apex1)

GAT:	120817316(apex1) 120819018(si:ch211-141o9.10)

PPUG:

119211037(apex1) 119212492(si:ch211-141o9.10)

AFB:	129090981(si:ch211-141o9.10) 129112515(apex1)

CLUM:

117726464(apex1) 117748974(si:ch211-141o9.10)

PSWI:

130200693(apex1)

MSAM:

119916257(si:ch211-141o9.10) 119918478(apex1)

SCHU:

122867679(si:ch211-141o9.10) 122871581(apex1)

CUD:	121505400(apex1) 121527890(si:ch211-141o9.10)

ALAT:

119010126(si:ch211-141o9.10) 119032248(apex1)

MZE:	101472544(apex1) 101485194

ONL:	100699309(apex1) 102081167

OAU:	116323453(apex1) 116327318(si:ch211-141o9.10)

OLA:	101166169 101172621(apex1)

OML:	112154484(si:ch211-141o9.10) 112158007(apex1)

CSAI:

133419355(si:ch211-141o9.10) 133424202(apex1)

XMA:	102234775(apex1)

XCO:	114160749(apex1)

XHE:	116727049 116736636(apex1)

PRET:

103459608(apex1)

PFOR:

103129175 103151290(apex1)

PLAI:

106935632(apex1) 106951310

PMEI:

106908493(apex1) 106925739

GAF:	122822821(si:ch211-141o9.10) 122826301(apex1)

PPRL:

129376048(apex1) 129377879(si:ch211-141o9.10)

CVG:	107089545 107098070(apex1)

CTUL:

119781472(apex1) 119793758(si:ch211-141o9.10)

GMU:	124875064(si:ch211-141o9.10) 124882857(apex1)

NFU:	107383288(apex1) 107388238

KMR:	108235861(si:ch211-141o9.10) 108244964(apex1)

ALIM:

106524319(apex1)

NWH:	119428391(apex1)

AOCE:

111580604(apex1) 111583578

MCEP:

124999748(apex1) 125022719

CSEM:

103382083 103383084(apex1)

POV:	109627051 109637508(apex1)

SSEN:

122758970(si:ch211-141o9.10) 122759818 122766906(apex1)

HHIP:

117753233(si:ch211-141o9.10) 117757569(apex1)

HSP:	118100325(si:ch211-141o9.10) 118101409(apex1)

PPLT:

128426470(si:ch211-141o9.10) 128428511(apex1)

SMAU:

118288121(si:ch211-141o9.10) 118317371(apex1)

LCF:	108888369 108889127(si:ch211-141o9.10)

SDU:	111219987 111224763(apex1)

SLAL:

111646116 111654771(apex1)

XGL:	120794056(si:ch211-141o9.10) 120804033(apex1)

HCQ:	109528822(apex1)

SSCV:

125992258

SBIA:

133493700(apex1)

PEE:	133396954(apex1)

PTAO:

133471735(apex1)

BPEC:

110159554 110164042(apex1)

MALB:

109960886(apex1) 109971857

BSPL:

114846193(si:ch211-141o9.10) 114861371(apex1)

SJO:	128380998(si:ch211-141o9.10) 128385363(apex1)

SASA:

100196733(apex1) 106576591 106609717(APEX1) 106609722

STRU:

115180410 115199169

OTW:	112217117(apex1)

OMY:	110490648 110490651

OGO:	124018456(apex1)

ONE:	115107150(apex1)

OKI:	109877668(apex1)

OKE:

118374000

SALP:

112071636(apex1)

SNH:	120050108 120050117

CCLU:

121550330 121551290

ELS:	105020316(apex1)

SFM:	108935940(apex1) 108940012

PKI:	111836487(apex1)

AANG:

118219306(apex1) 118220750(si:ch211-141o9.10)

LOC:	102689397(apex1) 102698435

PSPA:

121307881 121317943 121320140(apex1)

ARUT:

117415663(apex1) 117432771 117432946 117963003

PSEX:

120536993(si:ch211-141o9.10) 120539598(apex1)

LCM:	102356074(APEX1) 102359858

RTP:	109926487(apex1)

HOC:	132807649(apex1)

LERI:

129694917(apex1)

PMRN:

116944056(APEX1) 116956161

LRJ:

133348012

BFO:	118408039 118428752

BBEL:

109487420

CIN:

100176572

SCLV:

120326733 120326734 120328685

SPU:	584564 587280 592745

LPIC:

129258353 129259419 129269278

APLC:

ARUN:

AJC:

SKO:

DME:	Dmel_CG3178(Rrp1)

DER:	113564232 26526673

DSE:

116803620

DSI:	Dsimw501_GD27784(Dsim_GD27784)

DYA:	Dyak_GE29051

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI25713

DAZ:

DNV:

DHE:

BDR:

RZE:	108375931 108378106

TDA:

MDE:

LCQ:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ012006

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105678358(Rrp1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	655158 657541 658053 664052

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200726

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103505813 103512051

CLEC:

106666412

HHAL:

106685927(Rrp1)

NLU:

111046320

HVI:

124360242

MQU:

128992042

PHU:	Phum_PHUM026780

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:	119452973 119455564

RSAN:

119378749 119394277 119400468

RMP:	119172365 119179592

VDE:

VJA:

DPTE:

DFR:

CSCU:

CVS:

ABRU:

SDM:

LPOL:

PMEO:

CEL:	CELE_R09B3.1(exo-3) CELE_T05H10.2(apn-1)

CBR:	CBG_13421(Cbr-apn-1) CBG_18693(Cbr-exo-3)

CRQ:	GCK72_001619 GCK72_005119

NAI:	NECAME_00797 NECAME_09486

BMY:	BM_BM5310(Bma-exo-3)

LOA:	LOAG_01360 LOAG_10727

TSP:

Tsp_01310

HRO:	HELRODRAFT_186002

LGI:	LOTGIDRAFT_128104

PVUL:

126812052

PCAN:

112567112 112575233

BGT:	106061433 106076557

GAE:	121370325 121391380

HRF:

HRJ:

CRG:

CANU:

CVN:	111099552 111102061

OED:

125675462

MYI:	110453847 110461637

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115215723 115229756

LJP:

135481951

LAK:	106155683 106178207

SMM:	Smp_051320

OVI:	T265_15151

EGL:

EGR_00709

LLON:

135488023

NVE:	5504723 5504729

EPA:

110235943

ATEN:

116303599

ADF:	107341267 107345614

AMIL:

114958151 114975188

PDAM:

113664522 113666691

SPIS:

111324773 111325845

DGT:	114531495 114536308

XEN:

124443203

HMG:

100201725

HSY:

130644303

RES:	135685431 135692173

TAD:	TRIADDRAFT_21078 TRIADDRAFT_60990 TRIADDRAFT_62597

AQU:

100634205

THJ:

104803289

CRE:	CHLRE_03g175850v5

VCN:	VOLCADRAFT_56112

CSL:	COCSUDRAFT_18358

CVR:	CHLNCDRAFT_30910

MPP:	MICPUCDRAFT_5836

CME:	CYME_CMG142C CYME_CML016C

GSL:	Gasu_49160

CCP:	CHC_T00005119001

SCE:	YKL114C(APN1)

SEUB:

DI49_3263

SPAO:

SPAR_K01000

AGO:	AGOS_ABL054C

ERC:

Ecym_7413

KLA:	KLLA0_C14256g

KMX:	KLMA_30564(APN1)

LTH:	KLTH0D05104g

VPO:	Kpol_1033p64

ZRO:	ZYRO0G02838g

CGR:	2890520(GVI51_K11363)

NCS:	NCAS_0A04450(NCAS0A04450)

NDI:	NDAI_0K01490(NDAI0K01490)

TPF:	TPHA_0G03000(TPHA0G03000)

TBL:	TBLA_0I01300(TBLA0I01300)

TGB:	HG536_0A03890

TDL:	TDEL_0A02340(TDEL0A02340)

KAF:	KAFR_0D03110(KAFR0D03110)

KNG:	KNAG_0A06400(KNAG0A06400)

ZMK:	HG535_0D03190

SLUD:

SCDLUD_004122

DHA:	DEHA2F13838g

PIC:	PICST_30161

PGU:	PGUG_00958

SPAA:

SPAPADRAFT_140201

LBG:	92208671(LODBEIA_P34750)

CAL:	CAALFM_C306430WA(APN1)

CTP:	CTRG_02221

COT:	CORT_0C04060

CDU:	CD36_86400

CTEN:

18246537(APN1)

CLU:	CLUG_05578

CLUS:

A9F13_25g00110

CAUR:

CJI96_0005125

PPA:	PAS_chr3_0810

PKZ:	C5L36_0C09860

BNN:	FOA43_002913

BBRX:

BRETT_005211

OPA:	HPODL_01629

YLI:	2910116(YALI2_B00107g)

SLB:	AWJ20_4006(APN1)

NCR:

NCU10044

NTE:	NEUTE1DRAFT149885(NEUTE1DRAFT_149885)

SMP:	10809416(SMAC4_00377)

PAN:	PODANSg5747

PBEL:

QC761_110510(APN1)

PPSD:

QC762_110510(APN1)

PPSP:

QC763_110510(APN1)

PPSA:

QC764_110510(APN1)

TTT:	THITE_2113782

MTM:	MYCTH_114166

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_6597

SSCK:

SPSK_03279

FGR:	FGSG_01348

FPU:	FPSE_11516

FPOA:

FPOAC1_001448

FVN:	FVRRES_01652

FVR:	FVEG_01483

FOX:	FOXG_00033

NHE:	NECHADRAFT_74423

FFC:	NCS54_00050200

FKR:	NCS57_00048300

FMU:	J7337_000547

TRE:	TRIREDRAFT_58076

TRR:	M419DRAFT_8652

TATV:

25775766(TrAtP1_007986)

TASP:

36610316(TrAFT101_007494)

MAW:	19248903(APN1)

MAJ:

MAA_00232

MBRN:

26243263(APN1)

PCHM:

VFPPC_05491

CMT:

CCM_06661

AMUS:

LMH87_012052

PLJ:	28885365(PLICBS_006930)

PTKZ:

JDV02_001806(APN1)

VAL:	VDBG_05893

CFJ:	CFIO01_03739

CLUP:

CLUP02_05811

CHIG:

CH63R_00855

SAPO:

SAPIO_CDS3463

ELA:	UCREL1_7989

PFY:	PFICI_01564

SSL:	SS1G_13282

BFU:	BCIN_03g08450(Bcapn1)

MBE:

MBM_01289

PSCO:

LY89DRAFT_696138

GLZ:	GLAREA_02092

ANI:	ANIA_03947

AFM:	AFUA_6G08110

ACT:	ACLA_082550

NFI:	NFIA_053780

ANG:	An11g02010

AFV:	AFLA_001573

ALUC:

AKAW2_80170S

ACHE:

ACHE_80596A

APUU:

APUU_40403A

PCS:	N7525_005278

PDP:	PDIP_88670

POU:	POX_d05815

TMF:	EYB26_005900

TRG:	TRUGW13939_06455

CIM:	CIMG_01149

CPW:	CPC735_052320

URE:	UREG_01084

ABE:

ARB_07906

TVE:

TRV_04130

PBL:	PAAG_01173

PBN:	PADG_03656

AJE:	HCAG_05891

BGH:	BDBG_03376

PNO:	SNOG_15845

PTE:

PTT_04322

PTRR:

6339182(PtrM4_025560)

BZE:	COCCADRAFT_33421

BSC:	COCSADRAFT_84666

BOR:	COCMIDRAFT_83642

AALT:

CC77DRAFT_948012

ARAB:

EKO05_0000361

ZTR:	MYCGRDRAFT_86647

PFJ:	MYCFIDRAFT_64567

FFU:	CLAFUR5_08826

CBET:

CB0940_10452

BCOM:

BAUCODRAFT_109370

NPA:	UCRNP2_6508

TML:	GSTUM_00006772001

SOM:	SOMG_04461(apn1)

CNE:	CNH01280 CNK02560

CNB:

CNBL1230

CNG:	CNAG_01913 CNAG_05468

CGI:	CGB_L1330C

CDEU:

CNBG_3030 CNBG_4394

CDEP:

91086605(L203_102393) 91086760(L203_102548)

KMG:	30161354(I203_105729) 30162495(I203_101045)

KNE:	92179330(IAR55_002071) 92183336(IAR55_006078)

TMS:	TREMEDRAFT_33014 TREMEDRAFT_63758

TASA:

A1Q1_04735 A1Q1_07885

CCAC:

CcaHIS019_0210300(APN1)

PPL:	POSPLDRAFT_34471 POSPLDRAFT_91820

TVS:	TRAVEDRAFT_116703 TRAVEDRAFT_45617

DSQ:	DICSQDRAFT_58911 DICSQDRAFT_77688

PCO:	PHACADRAFT_120160

SHS:	STEHIDRAFT_119353 STEHIDRAFT_128523

HIR:	HETIRDRAFT_100374 HETIRDRAFT_240647 HETIRDRAFT_308415

PSQ:	PUNSTDRAFT_104380 PUNSTDRAFT_121434

ADL:	AURDEDRAFT_188851 AURDEDRAFT_79056

FME:	FOMMEDRAFT_86737

GTR:	GLOTRDRAFT_136611 GLOTRDRAFT_136836

LBC:	LACBIDRAFT_251065 LACBIDRAFT_306129

CCI:	CC1G_01133 CC1G_13815

ABP:	AGABI1DRAFT111155(AGABI1DRAFT_111155) AGABI1DRAFT131644(AGABI1DRAFT_131644)

ABV:	AGABI2DRAFT114752(AGABI2DRAFT_114752) AGABI2DRAFT190373(AGABI2DRAFT_190373)

PCUB:

JR316_0004080

MPR:	MPER_06696

MRR:	Moror_1046 Moror_16863

E1B28_008938 E1B28_011676

SCM:	SCHCO_02481697(SCHCODRAFT_02481697) SCHCO_02605548(SCHCODRAFT_02605548)

CPUT:

CONPUDRAFT_79799

SLA:	SERLADRAFT_373106

WSE:	WALSEDRAFT_51169 WALSEDRAFT_63512

WIC:	J056_003469 J056_004636

UMA:	UMAG_00308 UMAG_15027

PFP:	PFL1_00302 PFL1_02120

SGRA:

EX895_000535 EX895_003596

MGL:

MGL_4225

MRT:

MRET_2728

MSYM:

MSY001_1531

PGR:	PGTG_14718

PTRC:

PtA15_4A132

PSTR:

Pst134EA_011178

MLR:	MELLADRAFT_105457

VNX:	VNE69_01124

RIE:	OCT59_012185

DDI:	DDB_G0277701(apeA) DDB_G0279923(apnA)

DPP:	DICPUDRAFT_9650

EHI:	EHI_046670(213.t00004)

EDI:	EDI_124000

EIV:	EIN_057190 EIN_254720

ACAN:

ACA1_142260 ACA1_280690

PFA:	PF3D7_1332600

PFD:	PFDG_02884

PFH:	PFHG_02836

PREI:

PRSY57_1331600

PGAB:

PGSY75_1332600

PLAG:

39743562(PADL01_1331600)

PYO:	PY17X_1352400

PCB:	PCHAS_1352000

PBE:	PBANKA_1347400

PVV:	PVVCY_1305010

PKN:	PKNH_1268000

PVX:	PVX_082560

PCY:	PCYB_123010

PMAL:

PMUG01_12032000(APN1)

PBRS:

92372333(MKS88_004246)

PREL:

PRELSG_1264300(APN1)

PCOT:

PCOAH_00042610

TAN:

TA12590

TPV:

TP02_0334

TOT:	TOT_020000317

BEQ:	BEWA_020470

BBO:	BBOV_III005900

BMIC:

BMR1_03g03115

BBIG:

BBBOND_0307960

CPV:

cgd1_310

CHO:	Chro.10041

TGO:	TGME49_288680

BBES:

BESB_021240

TET:	TTHERM_001080610

PTM:	GSPATT00017292001 GSPATT00019416001

SPAR:

SPRG_10327

EHX:	EMIHUDRAFT_214364 EMIHUDRAFT_216212 EMIHUDRAFT_99628

GTT:	GUITHDRAFT_64084(APEX)

TBR:	Tb927.8.5510

TBG:	TbgDal_VIII5480

TCR:	507083.30 509901.170

LMA:	LMJF_16_0680

LIF:	LINJ_16_0680

LDO:	LDBPK_160680

LMI:	LMXM_16_0680

LMAT:

92515660(LSCM1_05703)

LBZ:	LBRM_16_0670

LPAN:

LPMP_160650

LOI:	92361474(LSCM4_05603)

NGR:	NAEGRDRAFT_58770

» show all

Reference

PMID:20699270

Authors

Fantini D, Vascotto C, Marasco D, D'Ambrosio C, Romanello M, Vitagliano L, Pedone C, Poletto M, Cesaratto L, Quadrifoglio F, Scaloni A, Radicella JP, Tell G

Title

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

Journal

Nucleic Acids Res 38:8239-56 (2010)
DOI:10.1093/nar/gkq691

Sequence

[hsa:328]

Reference

PMID:19401441

Authors

Barnes T, Kim WC, Mantha AK, Kim SE, Izumi T, Mitra S, Lee CH

Title

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA.

Journal

Nucleic Acids Res 37:3946-58 (2009)
DOI:10.1093/nar/gkp275

Sequence

[hsa:328] [rno:79116]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (2899)   
   KEGG GENES (1036)   
   KEGG MGENES (285)   
   RefGene (1542)   
   OC (36)   
Literature (2)   
   PubMed (2)   
All databases (2909)   

Download RDF

ORTHOLOGY: K10772

Entry

K10772                      KO

Symbol

APEX2

Name

AP endonuclease 2 [EC:3.1.11.2]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K10772  APEX2; AP endonuclease 2
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     K10772  APEX2; AP endonuclease 2
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     K10772  APEX2; AP endonuclease 2

Other DBs

GO:	0008296 0003906

Genes

HSA:	27301(APEX2)

PTR:	473625(APEX2)

PPS:	100975705(APEX2)

GGO:	101142413(APEX2)

PON:	100434759(APEX2)

PPYG:

129025038(APEX2)

NLE:	100594886(APEX2)

HMH:	116811721(APEX2)

SSYN:

129475542(APEX2)

MCC:	702084(APEX2)

MCF:	102140119(APEX2)

MTHB:

126946516

MNI:	105493770(APEX2)

CSAB:

103232031(APEX2)

CATY:

105598644(APEX2)

PANU:

101020803(APEX2)

TGE:	112615629(APEX2)

MLEU:

105548113(APEX2)

RRO:	104657179(APEX2)

RBB:	108540601(APEX2)

TFN:	117078256(APEX2)

PTEH:

111535798(APEX2)

CANG:

105505819(APEX2)

CJC:	100410557(APEX2)

SBQ:	101033991(APEX2)

CIMI:

108291481 108296997(APEX2)

ANAN:

105730481(APEX2)

CSYR:

103255487(APEX2)

MMUR:

105862243(APEX2)

LCAT:

123628896(APEX2)

PCOQ:

105824255(APEX2)

OGA:	100942871(APEX2)

MMU:	77622(Apex2)

MCAL:

110286626(Apex2)

MPAH:

110313652(Apex2)

RNO:	289662(Apex2l1) 317628(Apex2)

MCOC:

116089474(Apex2)

ANU:	117694759(Apex2)

MUN:	110540247(Apex2) 110559150

CGE:	100753797(Apex2) 100772896

MAUA:

101829419 101840890(Apex2)

PROB:

127217950(Apex2)

PLEU:

114702869(Apex2)

MORG:

121436599 121445010 121445032

MFOT:

126492164 126506471 126506472

AAMP:

119804604(Apex2) 119805971

NGI:	103738666(Apex2)

HGL:	101701150(Apex2)

CPOC:

100722391(Apex2)

CCAN:

109700224(Apex2)

DORD:

106000534(Apex2)

DSP:	122112014(Apex2)

PLOP:

125344239(Apex2)

NCAR:

124971390

MMMA:

107159880(Apex2)

OCU:

100350593

OPI:	101534100(APEX2)

TUP:	102493772(APEX2)

GVR:	103601424(APEX2)

CFA:	100855516(APEX2)

CLUD:

112673053(APEX2)

VVP:	112912374(APEX2)

VLG:	121483241(APEX2)

NPO:	129518686(APEX2)

AML:	100484412(APEX2)

UMR:	103682096(APEX2)

UAH:	113248665(APEX2)

UAR:	123789915(APEX2)

ELK:

111139793

MPUF:

101692269(APEX2)

MNP:	132007751(APEX2)

MLK:	131821538(APEX2)

NVS:	122897662(APEX2)

ORO:	101376591(APEX2)

EJU:	114200785(APEX2)

ZCA:	113930880(APEX2)

MLX:	118000302(APEX2)

NSU:	110589757(APEX2)

LWW:	102733454(APEX2)

FCA:	101095317(APEX2)

PYU:	121024788(APEX2)

PCOO:

112871008(APEX2)

PBG:	122477737(APEX2)

PVIV:

125157199(APEX2)

LRUF:

124522281

PTG:	102969410(APEX2)

PPAD:

109259215(APEX2)

PUC:

125932166

AJU:

106986449

HHV:	120226647(APEX2)

BTA:	511790(APEX2)

BOM:	102265511(APEX2)

BIU:	109555447(APEX2)

BBUB:

102406962(APEX2)

BBIS:

104981521(APEX2)

CHX:	102174734(APEX2)

OAS:	101116123(APEX2)

BTAX:

128069959(APEX2)

ODA:	120882187(APEX2)

CCAD:

122434334(APEX2)

MBEZ:

129535036(APEX2)

SSC:	100519003(APEX2)

CFR:	102504985(APEX2)

CBAI:

105069594(APEX2)

CDK:	105103538(APEX2)

VPC:	102528248(APEX2)

BACU:

103013850(APEX2)

BMUS:

118889122(APEX2)

LVE:	103072593(APEX2)

OOR:	101283465(APEX2)

DLE:	111169409(APEX2)

PCAD:

102982378(APEX2)

PSIU:

116747429(APEX2)

NASI:

112414612(APEX2)

ECB:	100062550(APEX2)

EPZ:	103541965(APEX2)

EAI:	106834246(APEX2)

MYB:	102245079(APEX2)

MYD:	102752277(APEX2) 102766559

MMYO:

118654253(APEX2) 118665796

MLF:	102422102(APEX2)

MDT:	132225169(APEX2) 132242697

PKL:	118706463(APEX2)

EFUS:

103301334(APEX2)

MNA:	107543147(APEX2)

DRO:	112308168(APEX2)

SHON:

118981783(APEX2)

AJM:	119055497(APEX2)

PDIC:

114505215(APEX2)

PHAS:

123814852(APEX2)

MMF:	118636460(APEX2)

PPAM:

129064603(APEX2)

HAI:	109396961(APEX2)

RFQ:	117020448(APEX2)

PALE:

102898078(APEX2)

PGIG:

120593537(APEX2)

PVP:	105307788(APEX2)

RAY:	107506599(APEX2)

MJV:	108389944(APEX2)

TOD:	119246129(APEX2)

SARA:

101557421(APEX2)

LAV:	100654358(APEX2)

TMU:

101341791

ETF:	101660658(APEX2)

DNM:	101444586(APEX2)

MDO:	100012903(APEX2)

GAS:	123253532(APEX2)

SHR:	100927463(APEX2)

AFZ:

127542477

PCW:	110203453(APEX2)

TVP:	118833382(APEX2)

OAA:	100079599(APEX2)

ASN:	102368546(APEX2)

AMJ:	102563647(APEX2)

CMY:	102936240(APEX2)

CCAY:

125628339(APEX2)

DCC:	122457299(APEX2)

CPIC:

101953753(APEX2)

TST:	117889087(APEX2)

CABI:

116818874(APEX2)

MRV:	120388527(APEX2)

ACS:	100567501(apex2)

ASAO:

132767894(APEX2)

PVT:	110078641(APEX2)

SUND:

121924220(APEX2)

PBI:	103059473(APEX2)

PMUR:

107286572(APEX2)

CTIG:

120318448(APEX2)

TSR:	106554007(APEX2)

PGUT:

117675455(APEX2)

APRI:

131193040(APEX2)

PTEX:

113443357(APEX2)

NSS:	113417752(APEX2)

VKO:	123029994(APEX2)

PMUA:

114588162(APEX2)

PRAF:

128405426(APEX2)

ZVI:	118097636(APEX2)

HCG:	128343519(APEX2)

GJA:	107121340(APEX2)

STOW:

125429707(APEX2)

EMC:	129346466(APEX2)

XLA:	446614(apex2.L)

XTR:	448512(apex2)

NPR:	108797520(APEX2)

RTEM:

120913132(APEX2)

BBUF:

120977703(APEX2)

BGAR:

122919578(APEX2)

MUO:	115463493(APEX2)

GSH:	117348784(APEX2)

DRE:	393115(apex2)

SRX:	107731139(apex2) 107745771

SANH:

107668008 107695293

SGH:	107549375 107550000

CCAR:

109061994 109065663(apex2)

CAUA:

113073437 113080923

CGIB:

127963658

PTET:

122349936(apex2)

LROH:

127169194(apex2)

OMC:	131545715(apex2)

PPRM:

120469279(apex2)

RKG:	130094686(apex2)

MAMB:

125279602(apex2) 125280118

CIDE:

127518166

CERY:

137026358(apex2)

MASI:

127414862 127423788

TROS:

130568254(apex2)

TDW:	130406894(apex2)

MANU:

129414135(apex2)

IPU:

108265419

IFU:	128607845(apex2)

PHYP:

113540849(apex2)

SMEO:

124400515(apex2)

TFD:	113656316(apex2)

TVC:	132853534(apex2)

TRN:	134318147(apex2)

AMEX:

103032472(apex2)

CMAO:

118813166(apex2)

EEE:	113589828(apex2)

CHAR:

105893656(apex2)

TRU:	101076869(apex2)

TFS:	130529927(apex2)

TNG:	GSTEN00005783G001

LCO:	104924685(apex2)

NCC:	104951560(apex2)

TBEN:

117483517(apex2)

CGOB:

115010836(apex2)

PGEO:

117449328(apex2)

GACU:

117547443(apex2)

EMAC:

134863570(apex2)

ELY:	117257941(apex2)

EFO:	125891386(apex2)

PLEP:

121946592(apex2)

SLUC:

116043502(apex2)

ECRA:

117947372(apex2)

ESP:	116692150(apex2)

PFLV:

114558385(apex2)

GAT:	120828788(apex2)

PPUG:

119222233(apex2)

AFB:	129100169(apex2)

CLUM:

117733198(apex2)

PSWI:

130199588(apex2)

MSAM:

119905225(apex2)

SCHU:

122883143(apex2)

CUD:	121517395(apex2)

ALAT:

119023264(apex2)

MZE:	101465054(apex2)

ONL:	100703860(apex2)

OAU:	116319532(apex2)

OML:	112159530(apex2)

CSAI:

133456251(apex2)

XMA:	102228428(apex2)

XCO:	114160486(apex2)

XHE:	116713145(apex2)

PFOR:

103139041(apex2)

PLAI:

106954380(apex2)

PMEI:

106906929(apex2)

GAF:	122839343(apex2)

PPRL:

129370185(apex2)

CVG:	107086748(apex2)

CTUL:

119782054(apex2)

GMU:	124871979(apex2)

NFU:	107390522(apex2)

KMR:	108231963(apex2)

ALIM:

106519332(apex2)

NWH:	119417550(apex2)

AOCE:

111588339(apex2)

MCEP:

125013127(apex2)

CSEM:

103385365(apex2)

POV:	109635154(apex2)

SSEN:

122776893(apex2)

HHIP:

117765379(apex2)

HSP:	118111230(apex2)

PPLT:

128442999(apex2)

SMAU:

118317368(apex2)

LCF:

108882165

SDU:	111234918(apex2)

SLAL:

111654169(apex2)

XGL:	120804331(apex2)

HCQ:

109512952

SSCV:

125987994

SBIA:

133495422(apex2)

PEE:	133399986(apex2)

PTAO:

133477017(apex2)

BPEC:

110164670(apex2)

MALB:

109966729(apex2)

BSPL:

114858218(apex2)

SJO:	128357264(apex2)

SASA:

106567314 106572385(apex2)

STRU:

115165756(apex2)

OTW:	112216173(apex2)

OMY:	110532470(apex2)

OGO:	124022501(apex2)

ONE:	115132323(apex2)

OKI:	109908152(apex2)

OKE:	118360853(apex2)

SALP:

111966632 111976292

SNH:	120059217(apex2)

CCLU:

121538510(apex2)

ELS:	105022379(apex2)

SFM:	108918403(apex2)

PKI:	111857076(apex2)

AANG:

118210618(apex2)

LOC:	102690374(apex2)

PSPA:

121328264(apex2)

ARUT:

117404258(apex2)

PSEX:

120542589(apex2)

LCM:	102352181(APEX2)

CMK:	103188060(apex2)

RTP:

109918764

CPLA:

122540168(apex2)

HOC:	132835914(apex2)

LERI:

129694363(apex2)

PMRN:

116952714(APEX2)

LRJ:	133356726(APEX2)

BFO:

BBEL:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AJC:

SKO:

BCOO:

FOC:

TPAL:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_305561

DMK:

DPZ:

PVM:

PJA:

PCHN:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

TSP:

HRO:	HELRODRAFT_94522

LGI:	LOTGIDRAFT_200437

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LAK:	106152580 106178902

SMM:	Smp_167500

SHX:	MS3_00004951(APEX2_1)

OVI:	T265_00178

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_19413

AQU:

ATH:

ALY:

CRB:

CSAT:

104721167 104729572 104729579

EUS:	EUTSA_v10024709mg

BRP:

103870940

BNA:	106348593 106446391

BOE:

106292286

RSZ:	108822903 130494304

THJ:

104807495

CPAP:

110822146

CIT:

102619750

CIC:	CICLE_v10025146mg

PVY:	116116719 116116808

MINC:

123199209

TCC:

18610767

GRA:

105803710

GHI:	107912813 107912988

GAB:

HSYR:

DZI:

GMX:

GSJ:

PVU:	PHAVU_003G261600g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:	107476704 127743850

AIP:

107624490

AHF:	112719686 112796363

LANG:

109350171

PCIN:

129322237

QSA:	O6P43_033611

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107786042 107812644

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110694701 110724742

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

OBR:

OGL:

BDI:

TDC:	119302658 119311334

TAES:

123104597 123112864 123122366

TUA:

125510158

LPER:

127302643

LRD:	124655492 124657884

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	121984654 122038371

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_134604 SELMODRAFT_405812 SELMODRAFT_405855 SELMODRAFT_430260 SELMODRAFT_81439

PPP:

112294403

CRE:	CHLRE_12g532750v5

VCN:	VOLCADRAFT_118317

CSL:	COCSUDRAFT_30771

CVR:	CHLNCDRAFT_136485

APRO:

F751_5145

OLU:	OSTLU_31440

OTA:	OT_ostta04g05210

MIS:	MICPUN_104463

MPP:	MICPUCDRAFT_70930

GSL:	Gasu_05140

CCP:	CHC_T00000985001

SCE:	YBL019W(APN2)

SEUB:

DI49_4697

SPAO:

SPAR_B00870

AGO:	AGOS_AFR016W

ERC:

Ecym_6193

KLA:	KLLA0_E10473g

KMX:	KLMA_20038(APN2)

LTH:	KLTH0H08250g

VPO:	Kpol_1007p2

ZRO:	ZYRO0C13222g

CGR:	2889633(GVI51_J04191)

NCS:	NCAS_0B05590(NCAS0B05590)

NDI:	NDAI_0B02930(NDAI0B02930)

TPF:	TPHA_0H00210(TPHA0H00210)

TBL:	TBLA_0A08780(TBLA0A08780)

TGB:	HG536_0D02440

TDL:	TDEL_0B04460(TDEL0B04460)

KAF:	KAFR_0C02810(KAFR0C02810)

KNG:	KNAG_0G01460(KNAG0G01460)

ZMK:	HG535_0E03190

SLUD:

SCDLUD_001589

DHA:	DEHA2G11814g

PIC:	PICST_28317(APN2)

PGU:	PGUG_04297

SPAA:

SPAPADRAFT_132284

LEL:	PVL30_001027(APN2)

LBG:	92209583(LODBEIA_P43870)

CAL:	CAALFM_C110650WA(APN2)

CTP:	CTRG_03279

COT:	CORT_0A11880

CDU:	CD36_09980

CTEN:

18249240(APN2)

CLU:	CLUG_05063 CLUG_05065

CLUS:

A9F13_03g01705

CAUR:

CJI96_0001287

PPA:	PAS_chr1-3_0055

PKZ:	C5L36_0D05490

BNN:	FOA43_000200

BBRX:

BRETT_000883

OPA:	HPODL_04785

YLI:	2910029(YALI2_C00131g)

SLB:	AWJ20_441(APN2)

NCR:

NCU01961

NTE:	NEUTE1DRAFT149501(NEUTE1DRAFT_149501)

SMP:	10804599(SMAC4_05405)

PAN:	PODANSg026

PBEL:

QC761_120580(APN2)

PPSD:

QC762_120580(APN2)

PPSP:

QC763_120580(APN2)

PPSA:

QC764_120580(APN2)

TTT:	THITE_2111508

MTM:	MYCTH_2298234

MGR:

MGG_02980

PPEI:

PpBr36_09389

PGRI:

PgNI_10379

TMN:	UCRPA7_3158

SSCK:

SPSK_05918

FGR:	FGSG_08889

FPU:	FPSE_08225

FPOA:

FPOAC1_005043

FVN:	FVRRES_05560

FVR:	FVEG_02488

FOX:	FOXG_03614

NHE:	NECHADRAFT_78136

FFC:	NCS54_00434000

FKR:	NCS57_00440500

FMU:	J7337_008831

TRE:	TRIREDRAFT_59147

TRR:	M419DRAFT_75428

TATV:

25778074(TrAtP1_001895)

TASP:

36615798(TrAFT101_000692)

MAW:	19249660(APN2_1)

MAJ:

MAA_03720

MBRN:

26245464(apn2)

PCHM:

VFPPC_04595

CMT:

CCM_06524

AMUS:

LMH87_001836

PLJ:	28882664(PLICBS_001325)

PTKZ:

JDV02_010144(APN2)

VAL:	VDBG_01987

VDA:	VDAG_02445

CFJ:	CFIO01_09393

CLUP:

CLUP02_14734

CHIG:

CH63R_09971

PFY:	PFICI_02897

SSL:	SS1G_04002

BFU:	BCIN_01g02130(Bcapn2)

MBE:

MBM_00652

PSCO:

LY89DRAFT_691728

GLZ:	GLAREA_11999

ANI:	ANIA_04736

AFM:	AFUA_3G06180

ACT:	ACLA_034130

NFI:	NFIA_024380 NFIA_071080

AOR:	AO090020000091

ANG:	An11g10190

AFV:	AFLA_010566

ALUC:

AKAW2_80882S(APN2)

ACHE:

ACHE_70468S(APN2)

APUU:

APUU_31165S(APN2)

PCS:	N7525_009208

PDP:	PDIP_00830

POU:	POX_g09024

TMF:	EYB26_008906

TRG:	TRUGW13939_11092

CIM:	CIMG_00405

CPW:	CPC735_058050

URE:	UREG_00453

ABE:

ARB_07318

TVE:

TRV_02049

PBL:	PAAG_05877

PBN:	PADG_06115

AJE:	HCAG_01173

BGH:	BDBG_06650

PNO:	SNOG_00377

PTE:

PTT_09967

PTRR:

90954693(PtrM4_040280)

BZE:	COCCADRAFT_471

BSC:	COCSADRAFT_169947

BOR:	COCMIDRAFT_89391

AALT:

CC77DRAFT_951750

ARAB:

EKO05_0004458

ZTR:	MYCGRDRAFT_88442(APN2)

PFJ:	MYCFIDRAFT_194837

FFU:	CLAFUR5_14201

CBET:

CB0940_05818

BCOM:

BAUCODRAFT_32166

NPA:	UCRNP2_4675

SPO:	2540679(apn2)

SOM:	SOMG_01291(apn2)

CNE:

CNI04070

CNB:

CNBH3880

CNG:	CNAG_04268

CGI:	CGB_H3800W

CDEU:

CNBG_2781

CDEP:

91085830(L203_101617)

KMG:	30165985(I203_103469)

KNE:	92181159(IAR55_003901)

TMS:	TREMEDRAFT_41480

TASA:

A1Q1_02824

CCAC:

CcaHIS019_0702550(APN2)

PPL:	POSPLDRAFT_31820

TVS:	TRAVEDRAFT_167909

DSQ:	DICSQDRAFT_167196

PCO:	PHACADRAFT_153651

SHS:	STEHIDRAFT_56900

HIR:	HETIRDRAFT_50142

PSQ:	PUNSTDRAFT_113069

ADL:	AURDEDRAFT_144188 AURDEDRAFT_86086

FME:	FOMMEDRAFT_137702

GTR:	GLOTRDRAFT_75533

RSX:	RhiXN_05120

LBC:	LACBIDRAFT_299606

CCI:	CC1G_05939

ABP:	AGABI1DRAFT70906(AGABI1DRAFT_70906)

ABV:	AGABI2DRAFT179106(AGABI2DRAFT_179106)

MRR:	Moror_17298

E1B28_007658

SCM:	SCHCO_02496919(SCHCODRAFT_02496919)

CPUT:

CONPUDRAFT_106852

SLA:	SERLADRAFT_477369

WSE:	WALSEDRAFT_65944

WIC:	J056_000033

UMA:	UMAG_10924

PFP:	PFL1_00045

SGRA:

EX895_000842

MGL:

MGL_3205

MRT:

MRET_2175

VNX:	VNE69_02071

NGD:	NGA_2014810(APEX2) NGA_2014820(APEX2)

PIF:	PITG_05586

PSOJ:

PHYSODRAFT_481346

SPAR:

SPRG_02459

EHX:	EMIHUDRAFT_456597 EMIHUDRAFT_465027

» show all

Reference

PMID:19443450

Authors

Burkovics P, Hajdu I, Szukacsov V, Unk I, Haracska L

Title

Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damage.

Journal

Nucleic Acids Res 37:4247-55 (2009)
DOI:10.1093/nar/gkp357

Sequence

[hsa:27301]

Reference

PMID:14599746

Authors

Fraser JL, Neill E, Davey S

Title

Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.

Journal

DNA Repair (Amst) 2:1253-67 (2003)
DOI:10.1016/j.dnarep.2003.08.005

Sequence

[spo:2540679]

Reference

PMID:18585982

Authors

Dan Y, Ohta Y, Tsuchimoto D, Ohno M, Ide Y, Sami M, Kanda T, Sakumi K, Nakabeppu Y

Title

Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus.

Journal

DNA Repair (Amst) 7:1437-54 (2008)
DOI:10.1016/j.dnarep.2008.05.003

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (2000)   
   KEGG GENES (782)   
   KEGG MGENES (185)   
   RefGene (1019)   
   OC (14)   
Literature (3)   
   PubMed (3)   
All databases (2009)   

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