KEGG   ORTHOLOGY: K10784
Entry
K10784                      KO                                     
Symbol
TRAV
Name
T cell receptor alpha chain V region
Pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04064  NF-kappa B signaling pathway
map04514  Cell adhesion molecules
map04612  Antigen processing and presentation
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04672  Intestinal immune network for IgA production
map04940  Type I diabetes mellitus
map05135  Yersinia infection
map05142  Chagas disease
map05144  Malaria
map05150  Staphylococcus aureus infection
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05202  Transcriptional misregulation in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05310  Asthma
map05320  Autoimmune thyroid disease
map05321  Inflammatory bowel disease
map05322  Systemic lupus erythematosus
map05323  Rheumatoid arthritis
map05330  Allograft rejection
map05332  Graft-versus-host disease
map05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K10784  TRAV; T cell receptor alpha chain V region
   04015 Rap1 signaling pathway
    K10784  TRAV; T cell receptor alpha chain V region
   04064 NF-kappa B signaling pathway
    K10784  TRAV; T cell receptor alpha chain V region
   04020 Calcium signaling pathway
    K10784  TRAV; T cell receptor alpha chain V region
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K10784  TRAV; T cell receptor alpha chain V region
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K10784  TRAV; T cell receptor alpha chain V region
   04660 T cell receptor signaling pathway
    K10784  TRAV; T cell receptor alpha chain V region
   04658 Th1 and Th2 cell differentiation
    K10784  TRAV; T cell receptor alpha chain V region
   04659 Th17 cell differentiation
    K10784  TRAV; T cell receptor alpha chain V region
   04672 Intestinal immune network for IgA production
    K10784  TRAV; T cell receptor alpha chain V region
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K10784  TRAV; T cell receptor alpha chain V region
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K10784  TRAV; T cell receptor alpha chain V region
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10784  TRAV; T cell receptor alpha chain V region
   05170 Human immunodeficiency virus 1 infection
    K10784  TRAV; T cell receptor alpha chain V region
   05162 Measles
    K10784  TRAV; T cell receptor alpha chain V region
   05169 Epstein-Barr virus infection
    K10784  TRAV; T cell receptor alpha chain V region
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K10784  TRAV; T cell receptor alpha chain V region
   05150 Staphylococcus aureus infection
    K10784  TRAV; T cell receptor alpha chain V region
  09174 Infectious disease: parasitic
   05144 Malaria
    K10784  TRAV; T cell receptor alpha chain V region
   05142 Chagas disease
    K10784  TRAV; T cell receptor alpha chain V region
  09163 Immune disease
   05310 Asthma
    K10784  TRAV; T cell receptor alpha chain V region
   05322 Systemic lupus erythematosus
    K10784  TRAV; T cell receptor alpha chain V region
   05323 Rheumatoid arthritis
    K10784  TRAV; T cell receptor alpha chain V region
   05320 Autoimmune thyroid disease
    K10784  TRAV; T cell receptor alpha chain V region
   05321 Inflammatory bowel disease
    K10784  TRAV; T cell receptor alpha chain V region
   05330 Allograft rejection
    K10784  TRAV; T cell receptor alpha chain V region
   05332 Graft-versus-host disease
    K10784  TRAV; T cell receptor alpha chain V region
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K10784  TRAV; T cell receptor alpha chain V region
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K10784  TRAV; T cell receptor alpha chain V region
Other DBs
GO: 0042105
Genes
PTR: 743494
MCC: 710149
MTHB: 126958307
CATY: 105593887
CJC: 100409044
MMUR: 105864623
PCOQ: 105814175
MCOC: 116084142 116084801
MFOT: 126493857
DORD: 106000422
OCU: 108178285
NPO: 129514977
AML: 105234922
MPUF: 101690739
NVS: 122894561
NSU: 123325714
PYU: 121031448
BTA: 100300850
BBUB: 102388997
CCAD: 122444227
CFR: 102514844
DLE: 111171298
ECB: 111772100
MYD: 107184444
MMYO: 118679427
MNA: 107531685
SHON: 118995118
PHAS: 123816833
MMF: 118629905
TMU: 111819117
GGA: 770074
CATA: 118258277
ACHC: 121233138
GCL: 127026642
RTD: 128919478
TGT: 104580244
ASN: 102386958
CMY: 119563598
CCAY: 125629018
TST: 117870553
CABI: 116817796
MRV: 120392894
ACS: 103280669
SUND: 121933880
PTEX: 113448834(PDCD1)
ZVI: 118095717
STOW: 125444408
EMC: 129339799
XLA: 398386(tra.L)
SRX: 107709316
SANH: 107658332
SGH: 107577925
TVC: 132855699
AMEX: 103021569
TRU: 101074543
MZE: 101471379
ONL: 102081292
OAU: 116312420
OMY: 110530952
PKI: 111847682
LCM: 106703676
HOC: 132808244
 » show all
Reference
  Authors
Krangel MS
  Title
Mechanics of T cell receptor gene rearrangement.
  Journal
Curr Opin Immunol 21:133-9 (2009)
DOI:10.1016/j.coi.2009.03.009
Reference
PMID:7591875
  Authors
Thiel C, Bontrop RE, Lanchbury JS
  Title
Structure and diversity of the T-cell receptor alpha chain in rhesus macaque and chimpanzee.
  Journal
Hum Immunol 43:85-94 (1995)
DOI:10.1016/0198-8859(94)00149-k
  Sequence
[ptr:743494]

KEGG   ORTHOLOGY: K10785
Entry
K10785                      KO                                     
Symbol
TRBV
Name
T-cell receptor beta chain V region
Pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04064  NF-kappa B signaling pathway
map04514  Cell adhesion molecules
map04612  Antigen processing and presentation
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04672  Intestinal immune network for IgA production
map04940  Type I diabetes mellitus
map05135  Yersinia infection
map05142  Chagas disease
map05144  Malaria
map05150  Staphylococcus aureus infection
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05202  Transcriptional misregulation in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05310  Asthma
map05320  Autoimmune thyroid disease
map05321  Inflammatory bowel disease
map05322  Systemic lupus erythematosus
map05323  Rheumatoid arthritis
map05330  Allograft rejection
map05332  Graft-versus-host disease
map05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04015 Rap1 signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04064 NF-kappa B signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04020 Calcium signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K10785  TRBV; T-cell receptor beta chain V region
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K10785  TRBV; T-cell receptor beta chain V region
   04660 T cell receptor signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04658 Th1 and Th2 cell differentiation
    K10785  TRBV; T-cell receptor beta chain V region
   04659 Th17 cell differentiation
    K10785  TRBV; T-cell receptor beta chain V region
   04672 Intestinal immune network for IgA production
    K10785  TRBV; T-cell receptor beta chain V region
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K10785  TRBV; T-cell receptor beta chain V region
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K10785  TRBV; T-cell receptor beta chain V region
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K10785  TRBV; T-cell receptor beta chain V region
   05170 Human immunodeficiency virus 1 infection
    K10785  TRBV; T-cell receptor beta chain V region
   05162 Measles
    K10785  TRBV; T-cell receptor beta chain V region
   05169 Epstein-Barr virus infection
    K10785  TRBV; T-cell receptor beta chain V region
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K10785  TRBV; T-cell receptor beta chain V region
   05150 Staphylococcus aureus infection
    K10785  TRBV; T-cell receptor beta chain V region
  09174 Infectious disease: parasitic
   05144 Malaria
    K10785  TRBV; T-cell receptor beta chain V region
   05142 Chagas disease
    K10785  TRBV; T-cell receptor beta chain V region
  09163 Immune disease
   05310 Asthma
    K10785  TRBV; T-cell receptor beta chain V region
   05322 Systemic lupus erythematosus
    K10785  TRBV; T-cell receptor beta chain V region
   05323 Rheumatoid arthritis
    K10785  TRBV; T-cell receptor beta chain V region
   05320 Autoimmune thyroid disease
    K10785  TRBV; T-cell receptor beta chain V region
   05321 Inflammatory bowel disease
    K10785  TRBV; T-cell receptor beta chain V region
   05330 Allograft rejection
    K10785  TRBV; T-cell receptor beta chain V region
   05332 Graft-versus-host disease
    K10785  TRBV; T-cell receptor beta chain V region
  09166 Cardiovascular disease
   05416 Viral myocarditis
    K10785  TRBV; T-cell receptor beta chain V region
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    K10785  TRBV; T-cell receptor beta chain V region
Other DBs
GO: 0042105
Genes
PTR: 100613861(BV10-1) 100614611 100615500(BV7-8) 100615597(BV7-9) 101057236(BV5-1) 101058202(BV25-1) 104007424 472538(BV2) 472543(BV6-3) 743326(BV7-2)
PPS: 100995080
GGO: 101135313 101137374
PON: 112128523
NLE: 101175807 101176031 101177905 101179555
MCC: 696306 697904 698785 703029
MTHB: 126951109
MNI: 105471202
CSAB: 103227080 103227095
CATY: 105584618 105584628 105589715
SBQ: 101031681
MPAH: 110316786
CGE: 100757609
HGL: 101714129
GVR: 103605353
UAH: 113265359
MPUF: 101686008
FCA: 111559549
PYU: 121028976
OAS: 101114438
BACU: 103003614
ECB: 106783094
MYD: 102759035
MMF: 118619714
HAI: 109378262
RFQ: 117017992
PGIG: 120589132
RAY: 107516945
SARA: 101538799
MDO: 100010040(TRB) 100617727
PCOC: 116239751
MGP: 104912840
TPAI: 128091911
LMUT: 125690572
CATA: 118247546
AFUL: 116490542
PRUF: 121362923
GFR: 106632040(PRSS1)
PHI: 102109901
PMAJ: 107211171
FPG: 101922302
EGZ: 104126619
TALA: 104369276
CPOO: 109319011(IGLL5)
PSS: 112546502
ACS: 100566582
PMUR: 107286922
APRI: 131190668
VKO: 123020254
PMUA: 114584196
PRAF: 128417775
XLA: 443731
RTEM: 120910385
BBUF: 121006028
GSH: 117350315
SRX: 107721945
SANH: 107664422
SGH: 107600656
CCAR: 109081555
SMEO: 124389565
TFD: 113659468
CHAR: 105899102
TFS: 130539820
TBEN: 117493846
GACU: 117557557
ELY: 117267113
EFO: 125901233
SLUC: 116045014
ECRA: 117958226
ESP: 116670530
PSWI: 130201701
MSAM: 119910797
ALAT: 119004446
OAU: 116321920
OLA: 101170740
PRET: 103458275
PFOR: 103144782
PLAI: 106938379
PMEI: 106922433
CVG: 107099422
GMU: 124855314
NWH: 119427246
AOCE: 111573535
CSEM: 103381735
SSEN: 122783119
HHIP: 117755670
HSP: 118116658
SMAU: 118288947
SLAL: 111662437
PTAO: 133488216
STRU: 115161858
OTW: 112255846
OGO: 124046816
OKI: 109881923
OKE: 127915743
SNH: 120023610
PSPA: 121305635
HOC: 132836553
 » show all
Reference
  Authors
Jackson AM, Krangel MS
  Title
Turning T-cell receptor beta recombination on and off: more questions than answers.
  Journal
Immunol Rev 209:129-41 (2006)
DOI:10.1111/j.0105-2896.2006.00342.x
Reference
  Authors
Krangel MS
  Title
Mechanics of T cell receptor gene rearrangement.
  Journal
Curr Opin Immunol 21:133-9 (2009)
DOI:10.1016/j.coi.2009.03.009

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