KEGG   ORTHOLOGY: K10977
Entry
K10977                      KO                                     

Name
aksA
Definition
methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
Pathway
ko00300  Lysine biosynthesis
ko00620  Pyruvate metabolism
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01120  Microbial metabolism in diverse environments
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K10977  aksA; methanogen homocitrate synthase
  09102 Energy metabolism
   00680 Methane metabolism
    K10977  aksA; methanogen homocitrate synthase
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K10977  aksA; methanogen homocitrate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.14  homocitrate synthase
     K10977  aksA; methanogen homocitrate synthase
    2.3.3.-  
     K10977  aksA; methanogen homocitrate synthase
Other DBs
RN: R00271 R08213 R08331 R08332
COG: COG0119
GO: 0004410
Genes
VIN: AKJ08_1878
LLU: AKJ09_03141
HOH: Hoch_0124
HOE: IMCC20628_00181 IMCC20628_03222
OTM: OSB_07940(leuA_1)
OCT: FTO60_04070
HAT: RC74_12750
SEDI: EBB79_17075
CLT: CM240_3130
CCE: Ccel_1624
DSY: DSY0970
DHD: Dhaf_2055
NAZ: Aazo_2787
MJA: MJ_0503
MMP: MMP0153(aksA)
MMD: GYY_00785(aksA)
MMAK: MMKA1_01580(cimA)
MMAO: MMOS7_01840(cimA)
MMAD: MMJJ_09310(leuA_1)
MAE: Maeo_0994
MVO: Mvol_1568
METF: CFE53_04770(aksA)
MTH: MTH_1630
MMG: MTBMA_c02150(leuA2)
METC: MTCT_1489
MWO: MWSIV6_0176(aksA)
METE: tca_01580(leuA_3)
MST: Msp_1099(leuA2)
METB: AW729_10320(aksA)
MRU: mru_0385(aksA)
MSI: Msm_0722
MEB: Abm4_0181(aksA)
MMIL: sm9_2160(aksA)
MEYE: TL18_01070(aksA)
MOL: YLM1_0056
METH: MBMB1_0290(aksA)
MFC: BRM9_1985(aksA)
MFI: DSM1535_0177(aksA)
MCUB: MCBB_0566(aksA)
MSUB: BK009_11615(aksA)
METN: BK008_07190(aksA)
METT: CIT01_06835(aksA)
METO: CIT02_05435(aksA)
MFV: Mfer_0964
MKA: MK1209(leuA)
TSI: TSIB_1630
MBAR: MSBR2_0170
MBAK: MSBR3_1047
MAC: MA_3342(leuA)
MMA: MM_2785
MMAC: MSMAC_1183
METM: MSMTP_1363
MTHR: MSTHT_0432
MTHE: MSTHC_0289
MHOR: MSHOH_1618
MFZ: AOB57_000055(aksA)
MBU: Mbur_0854(cimA)
MMET: MCMEM_0986
MMH: Mmah_1162
MHAZ: BHR79_07725(aksA)
MPY: Mpsy_2899
MZI: HWN40_08205(aksA)
MTP: Mthe_1533
MCJ: MCON_2596(leuA)
MHI: Mhar_1932
MHU: Mhun_1801
MLA: Mlab_0232
MBG: BN140_1718(aksA)
MEMA: MMAB1_2210(aksA)
MPI: Mpet_2488
MBN: Mboo_0598
MPL: Mpal_2142
MPD: MCP_1960(aksA)
MEZ: Mtc_1560(aksA)
RCI: RCIX2647(leuA-4)
BARB: AOA66_0016(aksA)
CCAI: NAS2_0974
LOKI: Lokiarch_10460(leuA_1) Lokiarch_53690(leuA_6)
PSYT: DSAG12_00097(leuA)
 » show all
Reference
PMID:9665716
  Authors
Howell DM, Harich K, Xu H, White RH
  Title
Alpha-keto acid chain elongation reactions involved in the biosynthesis of coenzyme B (7-mercaptoheptanoyl threonine phosphate) in methanogenic Archaea.
  Journal
Biochemistry 37:10108-17 (1998)
DOI:10.1021/bi980662p

KEGG   REACTION: R08332
Entry
R08332                      Reaction                               

Name
acetyl-CoA:2-oxopimelate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Definition
2-Oxopimelate + Acetyl-CoA + H2O <=> (R)-(Homo)3-citrate + CoA
Equation
Reaction class
RC00004  C00010_C00024
RC00067  C16588_C16598
Enzyme
2.3.3.-
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Orthology
K10977  methanogen homocitrate synthase [EC:2.3.3.14 2.3.3.-]
Other DBs
RHEA: 44931

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