KEGG   ORTHOLOGY: K10978Help
Entry
K10978                      KO                                     

Name
aksF
Definition
methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
Pathway
ko00300  Lysine biosynthesis
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01130  Biosynthesis of antibiotics
ko01210  2-Oxocarboxylic acid metabolism
ko01230  Biosynthesis of amino acids
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K10978  aksF; methanogen homoisocitrate dehydrogenase
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K10978  aksF; methanogen homoisocitrate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.87  homoisocitrate dehydrogenase
     K10978  aksF; methanogen homoisocitrate dehydrogenase
    1.1.1.-  
     K10978  aksF; methanogen homoisocitrate dehydrogenase
BRITE hierarchy
Other DBs
RN: R01934 R01936 R04862 R08214 R08215
COG: COG0473
Genes
MJA: MJ_1596
MFE: Mefer_0957
MVU: Metvu_0752
MFS: MFS40622_0058
MIF: Metin_0287
MJH: JH146_0764
MIG: Metig_0040
MMP: MMP0880(aksF)
MMQ: MmarC5_0688
MMX: MmarC6_1775
MMD: GYY_05110
MAE: Maeo_1484
MVO: Mvol_0791
MTH: MTH_184
METC: MTCT_0151
MWO: MWSIV6_0600(leuB1)
METE: tca_00168(hicd_1)
MST: Msp_0674
MSI: Msm_0373
MRU: mru_1033(aksF)
MEB: Abm4_0999(aksF)
MMIL: sm9_0644(aksF)
MEYE: TL18_03130
MOL: YLM1_0578
METH: MBMB1_1404(leuB1)
MFC: BRM9_0639(aksF)
MFI: DSM1535_0612(leuB1)
MCUB: MCBB_1645(leuB1)
MFV: Mfer_1273
MKA: MK1215(leuB_2)
MAC: MA_3748(leuB)
MBAR: MSBR2_2662
MBAK: MSBR3_2764
MMA: MM_0642
MMAC: MSMAC_0669
METM: MSMTP_0734
MTHE: MSTHC_0902
MTHR: MSTHT_2378
MHOR: MSHOH_0789
MMET: MCMEM_2087
MMH: Mmah_0129
MPY: Mpsy_2352
MTP: Mthe_0855
MCJ: MCON_1920(aksF)
MHI: Mhar_2394
MHU: Mhun_1797
MLA: Mlab_0235
MBG: BN140_3039(leuB3)
MEMA: MMAB1_2207(leuB)
MPI: Mpet_2492
MBN: Mboo_0602
MPL: Mpal_2146
MPD: MCP_1963(aksF)
MEZ: Mtc_1557(aksF)
RCI: RCIX2644(leuB-2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Howell DM, Graupner M, Xu H, White RH
  Title
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea.
  Journal
J Bacteriol 182:5013-6 (2000)
DOI:10.1128/JB.182.17.5013-5016.2000
  Sequence
[mja:MJ_1596]

KEGG   REACTION: R08215Help
Entry
R08215                      Reaction                               

Name
(-)-threo-iso(homo)3-citrate:NAD+ oxidoreductase (decarboxylating)
Definition
(-)-threo-Iso(homo)3-citrate + NAD+ <=> 2-Oxosuberate + CO2 + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00114  C16589_C16600
Enzyme
1.1.1.-
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Orthology
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]

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