KEGG ORTHOLOGY: K10988

ORTHOLOGY: K10988

Entry

K10988                      KO

Symbol

RAG2

Name

recombination-activating protein 2

Pathway

map04068

FoxO signaling pathway

map05340

Primary immunodeficiency

Disease

H00092

T-B-Severe combined immunodeficiency

H02554

Omenn syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K10988  RAG2; recombination-activating protein 2
09160 Human Diseases
  09163 Immune disease
   05340 Primary immunodeficiency
    K10988  RAG2; recombination-activating protein 2

Genes

HSA:	5897(RAG2)

PTR:	466490(RAG2)

PPS:	100982621(RAG2)

GGO:	101150280(RAG2)

PON:	100447476(RAG2)

PPYG:

129008566(RAG2)

NLE:	100596220(RAG2)

HMH:	116476343(RAG2)

SSYN:

129484227(RAG2)

MCC:	716837(RAG2)

MCF:	102124625(RAG2)

MTHB:

126936614

MNI:	105471575(RAG2)

CSAB:

103237494(RAG2)

CATY:

105586812(RAG2)

PANU:

101000786(RAG2)

TGE:	112607113(RAG2)

MLEU:

105534669(RAG2)

RRO:	104658367(RAG2)

RBB:	108535563(RAG2)

TFN:	117080230(RAG2)

PTEH:

111521903(RAG2)

CANG:

105510805(RAG2)

CJC:	100396079(RAG2)

SBQ:	101034251(RAG2)

CIMI:

108305746(RAG2)

ANAN:

105717288(RAG2)

CSYR:

103253467 103253468 103263675(RAG2)

MMUR:

105856825(RAG2)

LCAT:

123642605(RAG2)

PCOQ:

105814562(RAG2)

OGA:	100946435(RAG2)

MMU:	19374(Rag2)

MCAL:

110312575(Rag2)

MPAH:

110319179(Rag2)

RNO:	295953(Rag2)

MCOC:

116090548(Rag2)

ANU:	117703537(Rag2)

MUN:	110557495(Rag2)

CGE:	100754577(Rag2)

MAUA:

101831269(Rag2)

PROB:

127222198(Rag2)

PLEU:

114710747(Rag2)

MORG:

121440526 121465446(Rag2)

MFOT:

126504515

AAMP:

119815842(Rag2)

NGI:	103749516(Rag2)

HGL:	101724205(Rag2)

CPOC:

100723894(Rag2)

CCAN:

109693566(Rag2)

DORD:

105988106(Rag2)

DSP:	122117873(Rag2)

PLOP:

125361678(Rag2)

NCAR:

124958024

MMMA:

107135762(Rag2)

OCU:	100328951(RAG2)

OPI:	101517819(RAG2)

TUP:	102484736(RAG2)

GVR:	103601165(RAG2)

CFA:	483419(RAG2)

CLUD:

112663498(RAG2)

VVP:	112930433(RAG2)

VLG:	121501411(RAG2)

NPO:	129494441(RAG2)

AML:	100484130(RAG2)

UMR:	103659302(RAG2)

UAH:	113264890(RAG2)

UAR:	123799546(RAG2)

ELK:

111150029

LLV:

125079525

MPUF:

101693111(RAG2)

MNP:	132010617(RAG2)

MLK:	131822122(RAG2)

NVS:	122914306(RAG2)

ORO:	101386709(RAG2)

EJU:	114215239(RAG2)

ZCA:	113915401(RAG2)

MLX:	118015563(RAG2)

NSU:	110575731(RAG2)

LWW:	102729348(RAG2)

FCA:	101096513(RAG2)

PYU:	121043531(RAG2)

PCOO:

112865982(RAG2)

PBG:	122483714(RAG2)

PVIV:

125147149(RAG2)

LRUF:

124504702

PTG:	102960720(RAG2)

PPAD:

109279195(RAG2)

PUC:

125934496

AJU:

106976929

HHV:	120232542(RAG2)

BTA:	782387(RAG2)

BOM:	102286731(RAG2)

BIU:	109569898(RAG2)

BBUB:

102397757(RAG2)

BBIS:

104982480(RAG2)

CHX:	102173867(RAG2)

OAS:	101107628(RAG2)

BTAX:

128061013(RAG2)

ODA:	120876882(RAG2)

CCAD:

122449755(RAG2)

MBEZ:

129554056(RAG2)

SSC:	100151744(RAG2)

CFR:	102519710(RAG2)

CBAI:

105076496(RAG2)

CDK:	105106826(RAG2)

VPC:	102541438(RAG2)

BACU:

103020513(RAG2)

BMUS:

118898741(RAG2)

LVE:	103087961(RAG2)

OOR:	101278031(RAG2)

DLE:	111179768(RAG2)

PCAD:

102991832(RAG2)

PSIU:

116758657(RAG2)

NASI:

112404536(RAG2)

ECB:	100049881(RAG2)

EPZ:	103560232(RAG2)

EAI:	106837476(RAG2)

MYB:	102253401(RAG2)

MYD:	102765360(RAG2)

MMYO:

118665123(RAG2)

MLF:	102437925(RAG2)

MDT:	132242323(RAG2)

PKL:	118713122(RAG2)

EFUS:

103290871(RAG2)

MNA:	107531992(RAG2)

DRO:	112303393(RAG2)

SHON:

118983215(RAG2)

AJM:	119036485(RAG2)

PDIC:

114500388(RAG2)

PHAS:

123810225(RAG2)

MMF:	118628979(RAG2)

PPAM:

129080724(RAG2)

HAI:	109381100(RAG2)

RFQ:	117031086(RAG2)

PALE:

102887570(RAG2)

PGIG:

120606113(RAG2)

PVP:	105290064 105290065 105311290

RAY:	107499245(RAG2)

MJV:	108387880(RAG2)

TOD:	119255352(RAG2)

SARA:

101543746(RAG2)

SETR:

126017638(RAG2)

LAV:	100658016(RAG2)

TMU:

101345843

ETF:	101659442(RAG2)

DNM:	101436508(RAG2)

MDO:	100010149(RAG2)

GAS:	123252944(RAG2)

SHR:	100922847(RAG2)

AFZ:

127539683

PCW:	110192651(RAG2)

TVP:	118852698(RAG2)

OAA:	100073666(RAG2)

GGA:	423165(RAG2)

PCOC:

116229119(RAG2)

MGP:	100542788(RAG2)

CJO:	107314705(RAG2)

TPAI:

128086249(RAG2)

LMUT:

125694457(RAG2)

NMEL:

110401223(RAG2)

APLA:

101802914(RAG2)

ACYG:

106044294(RAG2)

CATA:

118250805(RAG2)

AFUL:

116489675(RAG2)

TGU:	100221953(RAG2)

LSR:	110484467(RAG2)

SCAN:

103826721(RAG2)

PMOA:

120512568(RAG2)

OTC:	121344868(RAG2)

PRUF:

121361006(RAG2)

GFR:	102041336(RAG2)

FAB:	101817082(RAG2)

OMA:	130254078(RAG2)

PHI:	102105553(RAG2)

PMAJ:

107206256(RAG2)

CCAE:

111930102(RAG2)

CCW:	104694107(RAG2)

CBRC:

103620713(RAG2)

ETL:	114056754(RAG2)

ZAB:	102065190(RAG2)

ZLE:	135448620(RAG2)

ACHL:

103806230(RAG2)

SVG:	106851513(RAG2)

MMEA:

130578104(RAG2)

HRT:	120754437(RAG2)

FPG:	101912350(RAG2)

FCH:	102058383(RAG2)

CCRI:

104154751(RAG2)

NNT:	104399309(RAG2)

SHAB:

115607217(RAG2)

ACUN:

113481139(RAG2)

TALA:

104355617(RAG2)

ACHC:

115334767(RAG2)

HALD:

104324432(RAG2)

HLE:	104843210(RAG2)

AGEN:

126049492

GCL:

127017363

CSTI:

104549107(RAG2)

LDI:	104352255(RAG2)

MNB:	103771036(RAG2)

DPUB:

104304788(RAG2)

AVIT:

104267401(RAG2)

BRHI:

104501384(RAG2)

EGZ:	104134048(RAG2)

NNI:	104009616(RAG2)

PCRI:

104024122(RAG2)

PCAO:

104046868(RAG2)

PADL:

103921678(RAG2)

AFOR:

103901555(RAG2)

FGA:	104069447(RAG2)

GSTE:

104254404(RAG2)

CLV:	102084267(RAG2)

MUI:	104544953(RAG2)

PGUU:

104468495(RAG2)

PLET:

104613858(RAG2)

EHS:	104502945(RAG2)

CMAC:

104473272(RAG2)

CUCA:

104056323(RAG2)

TEO:	104374948(RAG2)

BREG:

104629327(RAG2)

OHA:	104330074(RAG2)

ACAR:

104517799(RAG2)

CPEA:

104388405(RAG2)

CVF:	104295802(RAG2)

RTD:	128909456(RAG2)

AAM:	106498365(RAG2)

AROW:

112960918(RAG2)

NPD:	112943551(RAG2)

TGT:	104568689(RAG2)

DNE:	112981784(RAG2)

SCAM:

104152883(RAG2)

ASN:	102367820(RAG2)

AMJ:	102565473(RAG2)

CPOO:

109321600(RAG2)

GGN:	109298947(RAG2)

PSS:	102463895(RAG2)

CMY:	102938520(RAG2)

CCAY:

125638953(RAG2)

DCC:	119857679(RAG2)

CPIC:

101953357(RAG2)

TST:	117876999(RAG2)

CABI:

116839270(RAG2)

MRV:	120405281(RAG2)

ACS:	100561011(rag2)

ASAO:

132768603(RAG2)

PVT:	110090248(RAG2)

SUND:

121935139(RAG2)

PBI:	103053259(RAG2)

PMUR:

107293335(RAG2)

CTIG:

120301922(RAG2)

TSR:	106556864(RAG2)

PGUT:

117665477(RAG2)

APRI:

131188938(RAG2)

PTEX:

113438997(RAG2)

NSS:	113410175(RAG2)

VKO:	123026694(RAG2)

PMUA:

114585001(RAG2)

PRAF:

128413606(RAG2)

ZVI:	118085435(RAG2)

HCG:	128336868(RAG2)

GJA:	107114928(RAG2)

STOW:

125427477(RAG2)

EMC:	129324013(RAG2)

XLA:	100037211(rag2.S)

XTR:	100494391(rag2)

NPR:	108787827(RAG2)

RTEM:

120917065(RAG2)

BBUF:

120980946(RAG2)

BGAR:

122920488(RAG2)

MUO:	115467958(RAG2)

GSH:	117351995(RAG2)

DRE:	30658(rag2)

SRX:	107720771 107750738

SANH:

107670203 107673237

SGH:	107564622 107564623 107581808

CCAR:

109051083(rag2)

CAUA:

113098356(rag2)

CGIB:

128013708

PTET:

122330334(rag2)

LROH:

127156788(rag2)

OMC:	131534976(rag2)

PPRM:

120468291(rag2)

RKG:	130073695(rag2)

MAMB:

125247335(rag2)

CIDE:

127507443

CERY:

137015263(rag2)

MASI:

127435904

TROS:

130552246(rag2)

TDW:	130414636(rag2)

MANU:

129434131(rag2)

IPU:

108275346

IFU:	128618031(rag2)

PHYP:

113529908(rag2)

SMEO:

124392385(rag2)

TFD:	113660194(rag2)

TVC:	132857067(rag2)

TRN:	134320270(rag2)

AMEX:

103046156(rag2)

CMAO:

118811588(rag2)

EEE:	113589165(rag2)

CHAR:

105900788(rag2)

TRU:	101061349(rag2)

TFS:	130536717(rag2)

TNG:	GSTEN00022841G001

LCO:	104925261(rag2)

NCC:	104941237(rag2)

TBEN:

117491594(rag2)

CGOB:

115009965(rag2)

PGEO:

117448290(rag2)

GACU:

117545782(rag2)

EMAC:

134859474(rag2)

ELY:	117262767(rag2)

EFO:	125887447(rag2)

PLEP:

121950514(rag2)

SLUC:

116038597(rag2)

ECRA:

117949483(rag2)

ESP:	116694131(rag2)

PFLV:

114560562(rag2)

GAT:	120809627(rag2) 120812166

PPUG:

119196233(rag2)

AFB:	129108680(rag2)

CLUM:

117732222(rag2)

PSWI:

130195659(rag2)

MSAM:

119893179(rag2)

SCHU:

122875332(rag2)

CUD:	121515451(rag2)

ALAT:

119024490(rag2)

MZE:	101481301(rag2)

ONL:	100703785(rag2)

OAU:	116334527(rag2)

OLA:	101169356(rag2)

OML:	112152699(rag2)

CSAI:

133444700(rag2)

XMA:	102231685(rag2)

XCO:	114152620(rag2)

XHE:	116730258(rag2)

PRET:

103466124(rag2)

PFOR:

103133650(rag2) 103133652

PLAI:

106945044(rag2)

PMEI:

106921868(rag2)

GAF:	122835411(rag2)

PPRL:

129362646(rag2)

CVG:	107094313(rag2)

CTUL:

119793032(rag2)

GMU:	124858047(rag2)

NFU:	107388559(rag2)

KMR:	108239938(rag2)

ALIM:

106515591(rag2)

NWH:	119415570(rag2)

AOCE:

111563270(rag2)

MCEP:

125015112(rag2)

CSEM:

103380510(rag2)

POV:	109624278(rag2)

SSEN:

122776160(rag2)

HHIP:

117763073(rag2)

HSP:	118109786(rag2)

PPLT:

128444750(rag2)

SMAU:

118315789(rag2)

LCF:

108875221

SDU:	111228686(rag2)

SLAL:

111655325(rag2) 111665854

XGL:	120793454(rag2)

HCQ:	109530317(rag2)

SSCV:

125970823

SBIA:

133502250(rag2)

PEE:	133402803(rag2)

PTAO:

133477873(rag2)

BPEC:

110165931(rag2)

MALB:

109968739(rag2)

BSPL:

114857051(rag2)

SJO:	128358882(rag2)

SASA:

106561305(rag2)

STRU:

115197318(rag2)

OTW:	112218682(rag2)

OMY:	110497172(rag2)

OGO:	124035643(rag2)

ONE:	115134152(rag2)

OKI:	109867340(rag2)

OKE:	118395751(rag2)

SALP:

111962441(rag2)

SNH:	120066379(rag2)

CCLU:

121532207(rag2)

ELS:	105018379(rag2)

SFM:	108942123(rag2)

PKI:	111859495(rag2)

AANG:

118214867(rag2)

LOC:	102682206(rag2)

PSPA:

121295047(rag2)

ARUT:

117432347 117434441

PSEX:

120517628(rag2)

LCM:	102361038(RAG2)

CMK:	103174960(rag2)

RTP:	109930494(rag2)

CPLA:

122558035(rag2)

HOC:	132824259(rag2)

LERI:

129705683(rag2)

» show all

Reference

PMID:2360047

Authors

Oettinger MA, Schatz DG, Gorka C, Baltimore D

Title

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination.

Journal

Science 248:1517-23 (1990)
DOI:10.1126/science.2360047

Sequence

[mmu:19374]

Reference

PMID:12045092

Authors

Gellert M

Title

V(D)J recombination: RAG proteins, repair factors, and regulation.

Journal

Annu Rev Biochem 71:101-32 (2002)
DOI:10.1146/annurev.biochem.71.090501.150203

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (665)   
   KEGG GENES (410)   
   KEGG MGENES (188)   
   RefGene (66)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (674)   

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