KEGG ORTHOLOGY: K11041

ORTHOLOGY: K11041

Entry

K11041                      KO

Symbol

eta

Name

exfoliative toxin A/B

Pathway

map05150

Staphylococcus aureus infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K11041  eta; exfoliative toxin A/B
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02042 Bacterial toxins
    K11041  eta; exfoliative toxin A/B
Bacterial toxins [BR:ko02042]
Type III toxins: Intracellular toxins
  Others
   Exfoliative toxin type A
    K11041  eta; exfoliative toxin A/B
Type I toxins: Toxins that act from the cell surface
  Superantigens
   K11041  eta; exfoliative toxin A/B

Other DBs

COG:

COG1275

TC:

2.A.16

Genes

PSHI:

SAMEA2665130_1049

EBB:

F652_160

YRU:

BD65_1929

YRB:	UGYR_09935

YMO:	HRD69_02285

YAS:	N0H69_14185

YEG:	PL78_08050

SOD:

Sant_1930

EIC:	NT01EI_3089

ETD:

ETAF_2501

ETE:

ETEE_0937

ETR:

ETAE_2760

ETC:	ETAC_13300

EDW:	QY76_06660

EDL:	AAZ33_14580

EHO:	A9798_03455

HAV:	AT03_05790

HPAR:

AL518_20190

OPO:	DSM2777_20670

BTO:

BTRE:

BTRH:

BTRA:

VCH:

VCF:	IR04_16735

VCS:

MS6_2061

VCE:	Vch1786_I1815

VCQ:	EN18_14690

VCJ:	VCD_002022

VCI:

O3Y_11150

VCO:	VC0395_A1906

VCR:	VC395_2439

VCM:	VCM66_2246

VCL:	VCLMA_A2038

VCX:	VAA049_562

VCZ:	VAB027_2957

VVU:

VV1_1793

VVY:	VV2617 VVA1088

VVM:	VVMO6_00684 VVMO6_04003

VVL:	VV93_v1c23320 VV93_v1c40300

VPA:

VP2377

VPB:	VPBB_2206 VPBB_A1067

VPK:	M636_10045

VPF:	M634_14280 M634_20725

VPH:	VPUCM_0862

VHA:	VIBHAR_03304 VIBHAR_06234

VCA:	M892_14580 M892_20875

VAG:	N646_1494 N646_3944

VEX:	VEA_002682

VDB:	AL552_20530

VHR:	AL538_05790 AL538_26085

VNA:	PN96_01995

VOW:	A9237_12145 A9237_22940

VRO:	BSZ04_07215 BSZ04_11630

VSP:	VS_0672 VS_II0565

VEJ:	VEJY3_12355

VFU:	vfu_A02836 vfu_B00268

VNI:	VIBNI_A0543 VIBNI_B1203

VAN:	VAA_01013 VAA_03638

LAG:	N175_04410 N175_18385

VAU:	VANGNB10_cI2102c VANGNB10_cII0271c

VCY:	IX92_02690 IX92_21000

VCT:	JV59_18655 JV59_36000

VTU:	IX91_03420 IX91_20640

VEU:	IXK98_07130 IXK98_11995

VSI:	MTO69_10355 MTO69_14475

VFL:	AL536_04210 AL536_17390

VMI:	AL543_06425

VBR:	A6E01_03030 A6E01_14615

VSC:	VSVS12_02462 VSVS12_03628

VSH:	BSZ05_02525 BSZ05_20785

VQI:	CCZ37_10180 CCZ37_17725

VTA:	A1506 B1773

VAF:	D1115_03605 D1115_17660

VNL:	D3H41_12940

VCC:	FAZ90_11630 FAZ90_20905

VAS:	GT360_19910

VAQ:	FIV01_03075(tehA) FIV01_15885

VKA:	BTD91_09870 BTD91_19560

VZI:	G5S32_15275

VNV:	IF132_18965

VGI:	MID13_03295 MID13_20335

VSL:	LTQ54_05420 LTQ54_19940

VPL:	SA104470976_00496(tehA)

VPG:	LZI70_03645 LZI70_17345

VOS:	KNV97_01730

VTI:	CEQ48_07385

VCRA:

IS519_06905 IS519_20430

VNP:	KW548_24635

VLE:	ISX51_10400 ISX51_18090

VSY:	K08M4_23230 K08M4_35250

VMT:	QYQ96_02810

VIS:	VspSTUT16_06770

VIO:	AB2S62_11210 AB2S62_15490

VCK:	PG915_12670 PG915_16395

VID:	DBX26_11115

VIP:	H9L11_03070

VFI:

VF_0580

VFM:	VFMJ11_0594

VSA:	VSAL_I0679

AWD:	AWOD_I_0561

PPR:	PBPRA3000(VV20541) PBPRB0082(VC2323)

PGB:	H744_1c1613 H744_2c0892

PDS:	CAY62_11280

PGH:	FH974_02910 FH974_24785

PHOT:

L4174_003020

PPIL:

ACJZU6_04700

GHO:	AL542_01615 AL542_06290

GKD:	K6Q96_03145

PMAI:

SALY:

SCOT:

PLAS:

SON:

SFR:

SAZ:

SBL:

SBM:	Shew185_2687

SBN:	Sbal195_2766

SBP:	Sbal223_1697

SBT:	Sbal678_2771

SBS:	Sbal117_2795

SBB:	Sbal175_1679

SLO:

Shew_2530

SPC:	Sputcn32_2372

SHP:	Sput200_2398

SSE:

Ssed_1717

SPL:

Spea_1679

SHE:	Shewmr4_1498

SHM:	Shewmr7_1565

SHN:	Shewana3_1559

SHW:	Sputw3181_1637

SHL:

SWD:

SWP:

SVO:

SHF:	CEQ32_01950

SJA:	SJ2017_0963

SPSW:

Sps_03560

SBJ:	CF168_12970

SMAV:

CFF01_06635

SHEW:

CKQ84_16990

SALG:

BS332_16430

SLJ:	EGC82_05570

SPOL:

FH971_16050

SKH:	STH12_01147

SLIT:

SCAA:

SPSH:

SEUR:

SCYP:

SSEM:

SINV:

SXM:	MKD32_07860

SVM:	KDH10_002230

SHEJ:

SSEH:

SCHK:

SAEG:

SMES:

SHAO:

SZH:	K0H63_08035

SSPA:

SHNS:

SRHS:

SMAY:

SOG:	RA178_08600

SPSR:

SHEA:

SHEL:

SHEH:

SHEM:

PTN:	PTRA_a2671

PSM:

PSM_A0933

PIA:	PI2015_0915

PART:

PARC_a2942

PTD:	PTET_a1057

PSEN:

PNC201_10770

PDV:	FFU37_10960

PFLI:

PMAZ:

PSLC:

CATT:

PSY:	PCNPT3_04705

FBL:

Fbal_3086

MVS:

MVIS_1317

MMAA:

FR932_11495

MOQ:	HWV03_15775

ZPL:	ZBT109_1029

KUS:	B9G99_06020 B9G99_06150

KMA:	B9H00_08980

KUY:	FY550_00520

SAJS:

QO259_16585

MPC:	Mar181_1651

MARS:

A8C75_06425

MRZ:	KDW95_09785

ENW:	MJO57_26655

EEI:	NX720_05675

ENG:	O2T12_19940

AHA:

AHA_2100

AHY:	AHML_12505

AHD:	AI20_07530

AHR:	V428_12905

AHP:	V429_12925

AHJ:	V469_10140

AHH:	RY45_12325

AHI:	VU14_09905

AAJ:	BOQ57_12135

ASA:

ASA_2197

AEO:	O23A_p1259

AVR:

B565_1724

AVO:	AMS64_08520

AMED:

B224_2090

ASR:	WL1483_3106

ADH:	CK627_14280

ACAV:

VI35_10165

AEM:	CK911_05475

AEA:	C2U39_10075

ARV:	C7N77_14930

AES:	C2U30_03600

AEL:	NCTC12917_01969(tehA)

ASIM:

FE240_07345

AALL:

I6G90_06645

AJD:	I6H43_01020

ARIV:

KYK33_06760

ASAA:

KXJ75_11250

AEJ:	E5E97_17145

ABES:

AERO:

AERZ:

OCE:

OPE:	PU634_15670

OCM:	CBP12_10350

OPF:	CBP31_07370

NBA:	CUN60_01750 CUN60_04055

IOD:	EJO50_13195

IFL:	C1H71_08660

CHIZ:

CFON:

CMAV:

LHK:

JAB:	VN23_17735

OFO:	BRW83_1284(tehA)

SUTT:

SUTMEG_12790

SUTK:

FG381_02760

SWS:	I6J16_05445

PSF:

PSE_p0340

DEO:	CAY53_04155

TPED:

TPE_0927

BHY:	BHWA1_02327

BHD:	BHYOB78_04550

BRM:

Bmur_1960

BPO:	BP951000_0930

BPJ:	B2904_orf434

BPIP:

BPP43_10420

BPW:

WESB_2252

BIP:

Bint_2347

BHP:	BHAMNSH16_04485

FLL:	EI427_24905

FKA:	KM029_00875 KM029_20870

LYZ:	DCE79_09325

LYC:	FH508_0010900

SA1016

SAV:

SAV1173

SAW:

SAHV_1163

SAH:	SaurJH1_1256

SAJ:	SaurJH9_1231

SAM:

SAS:

SAR:

SAC:

SAX:	USA300HOU_1110

SAA:	SAUSA300_1065

SAO:	SAOUHSC_01133

SAE:	NWMN_1082(eta)

SAD:

SAAV_1141

SUU:	M013TW_1104

SUV:	SAVC_05015

SUE:	SAOV_1171c

SUJ:	SAA6159_01023

SUK:	SAA6008_01125(eta)

SUC:	ECTR2_1027

SUT:	SAT0131_00875 SAT0131_01217 SAT0131_02153

SUQ:	HMPREF0772_12060

SUZ:

MS7_1128

SUD:	ST398NM01_1167

SUX:	SAEMRSA15_10040

SUW:	SATW20_11650

SUG:

SAPIG1167

SUF:	SARLGA251_10820

SAUA:

SAUE:

SAUN:

SAUS:

SAUU:

SAUG:

SAUZ:

SAUT:

SAUJ:

SAUK:

SAUQ:

SAUV:

SAUW:

SAUX:

SAUY:

SAUF:

SAB:

SUY:	SA2981_1129

SAUB:

SAUM:

SAUC:

SAUR:

SAUI:

SAUD:

SAMS:

SUH:	SAMSHR1132_10140

SCA:

SCA_2302

SSD:	SPSINT_0069

SDT:	SPSE_2408(speta)

SHU:	SHYC_11755

SAGQ:

EP23_10415

SEQO:

SE1039_23990

SSIF:

AL483_10920

SCV:	A4G25_08655

SLZ:	B5P37_05445

SCOH:

BZ166_05455

SURY:

MUA21_11820

SNL:	BJD96_01205

SKL:	C7J89_01875

SARL:

SAP2_02700(ydiA)

SSH:	NCTC13712_01115

SROT:

STAP:

SSTE:

MLEN:

MVT:	I6J10_10725

SBAH:

RQP18_00270

BTHS:

CNY62_05055

GOT:	AXE85_07090

GMO:	NCTC11323_00433

GEQ:	CG018_00695

GSA:	FOC50_02100

GHA:	NCTC10459_00499

SIV:

SSIL_2238

SSIL:

SOLI23_07480

SOB:	CSE16_06695

KUR:

ASO14_235

KZO:	NCTC404_01094

LLA:	L181867(ydiA)

LLK:	LLKF_0429(ydiA)

LLT:	CVCAS_0361(ydiA)

LLS:	lilo_0341(ydiA)

LLD:	P620_02320

LLX:	NCDO2118_0437

LLJ:	LG36_0377(ydiA)

LLM:

llmg_0394

LLC:	LACR_0424 LACR_D35

LLR:	llh_14000 llh_2210

LLN:	LLNZ_02055

LLI:	uc509_0398 uc509_p8013

LLW:

kw2_0377

LGR:

LCGT_0209

LGV:

LCGL_0209

LTI:	JW886_03440

LPET:

lgb_00216

LFO:	LMK00_01035

LACN:

QJV49_09325

SPY:

SPy_0918

SPZ:	M5005_Spy0720

SPYM:

M1GAS476_0785

SPYA:

A20_0764(eta)

SPM:	spyM18_0975

SPG:	SpyM3_0632

SPS:

SPs1220

SPH:	MGAS10270_Spy0779

SPI:	MGAS10750_Spy0814

SPJ:	MGAS2096_Spy0792

SPK:	MGAS9429_Spy0777

SPF:

SpyM51087

SPA:	M6_Spy0746

SPB:	M28_Spy0700

STG:	MGAS15252_0749

STX:	MGAS1882_0745

SOZ:	Spy49_0728

STZ:	SPYALAB49_000749

SPN:

SP_0410

SPD:

SPD_0374

SPR:	spr0371(shetA)

SPW:	SPCG_0409(shetA)

SJJ:

SPJ_0397

SNV:	SPNINV200_03720

SPX:

SNT:

SND:

SPNN:

SNE:	SPN23F03860

SPV:

SPH_0518

SNC:	HMPREF0837_10701

SNM:	SP70585_0481

SPP:

SPP_0441

SNI:	INV104_03530

SPNG:

HMPREF1038_00454

SNB:	SP670_0483

SNP:

SPAP_0429

SNX:	SPNOXC03980

SNU:	SPNA45_01643

SPNE:

SPNU:

SPNM:

SPNO:

SAG:

SAN:

SAK:

SGC:	A964_1187(eta)

SAGM:

SAGI:

SAGR:

SAGT:

SAGE:

SAGG:

SAGN:

SAGJ:

SMU:

SMC:	SmuNN2025_1866

SMUT:

SMUGS5_09590

SMJ:	SMULJ23_1890

SMUA:

SMUFR_1848

STC:	str0650(eetB)

STL:	stu0650(eetB)

STE:

STER_0699

STN:

STND_0649

STU:	STH8232_0843

STW:

Y1U_C0624

STHE:

T303_04420

STHS:

AVT04_01675

SSA:	SSA_1927(shetA)

SGO:

SGO_1087

SUB:

SUB1136

SDS:

SDEG_1286

SDG:	SDE12394_06755

SDA:

GGS_1169

SDC:

SDSE_1267

SDQ:	SDSE167_1413

SMB:	smi_1720(shetA)

SGW:	D7D53_00825

STOY:

STYK_16120(shetA)

SOR:

SOR_1613

STK:

STP_0987

SCP:	HMPREF0833_11286

SCF:

Spaf_1922

SSR:	SALIVB_1418

STF:	Ssal_01498

STJ:	SALIVA_0660

STRS:

SSAL8618_03640

SSAH:

HSISS4_00566(eetB)

STD:	SPPN_02620

SIF:	Sinf_0933 Sinf_0965

SOI:	I872_05205

SIK:

K710_0750

SIQ:	DQ08_03605

SIO:	DW64_03600

SIZ:	SI82_03840

SLU:

KE3_1047

SIG:	N596_06330

SIP:	N597_08210

STV:	V470_07900

SPAT:

STRA:

STRN:

SSOB:

SEQI:

SKI:	D7D50_04020

SRAT:

FY406_02630

SPLR:

C0J00_05940

SVB:	NCTC12167_00691

SCAI:

NCTC12191_01413

SLAT:

J4854_09435

SAUP:

NCTC3168_00954

SVF:	NCTC3166_01794

SOS:	INT76_01440

SRUM:

GPZ88_09090

SRUN:

LPB404_09670

SPAM:

SP4011_18480(shetA)

SDID:

SDEN:

SLIN:

SNID:

SINS:

FPEN:

LCA:

LCZ:	LCAZH_2601

LCS:

LCBD_2816

LCE:

LC2W_2791

LCW:	BN194_27460

LCL:	LOCK919_2855

LPQ:	AF91_13055

LPI:	LBPG_01197

LPAP:

LBPC_2579

LCB:	LCABL_28000(ydiA)

LCX:	LCA12A_0300

LRH:	LGG_02621(ydiA)

LRG:

LRHM_2517

LRL:	LC705_02625(ydiA)

LRA:

LRHK_2728

LRO:	LOCK900_2616

LRC:	LOCK908_2699

LCHI:

KG086_11875

LZE:	KG087_13055

LHN:	LHUE1_000724

LPAH:

LACPH_002474

LSB:	LACSTY_002552

LBH:

Lbuc_2301

LBN:	LBUCD034_2401(tehA)

LPAR:

FAM21731_01097

LCU:	PL11_003940

LKF:	DNL43_04605

LHIL:

G8J22_02735

LBT:	AYR52_00930

LCY:	LC20004_00315

LMAE:

FGL90_06600

LDX:	LH506_07915

WJO:	FOL01_1873

WPA:	CO680_08970

AFK:	ACNAN0_01555

EFA:

EF0645

EFL:

EF62_1014

EFI:	OG1RF_10377

EFD:	EFD32_0459

EFS:

EFS1_0492

EFN:	DENG_00673(eta)

EFQ:

DR75_2593

ENE:

ENT_24740

EFC:	EFAU004_00552

EFAU:

EFAU085_00490

EFU:	HMPREF0351_10566

EFM:

M7W_729

EFT:	M395_02705

EHR:

ECAS:

EMU:

EDU:

EGA:	AL523_08915

EAV:	EH197_12510

ESG:	EsVE80_18680

ELAC:

I4Q40_02885

EIE:	ENLAB_25570(tehA)

EDS:	PML78_11160

EMS:	P3T75_03380

ENI:	CXM95_03990

ENQ:	RBL01_002470

THL:

TEH_02580

TEY:	GLW17_05705

VAC:	E4Z98_07345

VAO:	FA707_02030

VAH:	G7081_05275

VCP:	H9L18_05070

VHY:	G7082_01075

VFV:	K5K99_13190

ASAN:

AWM72_03560

ABAE:

CL176_10165

CDJ:	BFC22_02700

DPM:	FNV33_08280

DST:	VUQ06_05395

GEG:	LK443_06365

CPF:

CPR:

CBO:

CBA:

CBH:

CBY:

CBL:

CBB:

CBI:

CBF:

CBM:

CBJ:	H04402_01589

CSB:	CLSA_c26500

CBV:	U729_1159 U729_1818

CLD:	CLSPO_c15490

CACE:

CACET_c13930

CFM:	BJL90_12420

CCHV:

CARG:

CSEP:

CFER:

CGAS:

CCAA:

CTAG:

CLOL:

ASF:

ASM:	MOUSESFB_0725(mae1)

ASO:	SFBmNL_00858

ASB:	RATSFB_0648(mae1)

CALE:

SARJ:

PROQ:

ACAE:

CCOM:

BPRO:

BCOC:

BLIQ:

BLAR:

CPY:

LACY:

CSCI:

CHYL:

CSH:	Closa_1051

LXA:	OW255_19390

ARF:	AR1Y2_2813

ACAC:

EYQ97_04240

LUA:	D4A81_07980

LGG:	QJR73_07830

ECLF:

QMP25_06940

DLO:	K5I24_07500

SCAZ:

ACI3DN_05200

MDV:	C5Q96_00735

MNL:	QU661_02000

AMT:

Amet_3721

AOE:

Clos_0261

GFE:	Gferi_14140

CSPO:

QNI18_03835

PBIF:

KXZ80_03485 KXZ80_06880

PSOR:

RSJ16_03505 RSJ16_07820

CDF:	CD630_30190

PDC:	CDIF630_03304

CDC:	CD196_2808

CDL:	CDR20291_2855

PDF:	CD630DERM_30190

ROC:	HF520_00745

RHOM:

FRIFI_0275

TMY:	TEMA_02910

TEB:

T8CH_0950

TOC:

Toce_1530

HPK:	Hprae_0446

HALS:

D7D81_09030

AAR:	Acear_2294

PMIC:

NW74_01950

MHAP:

JFY71_11865

MFOM:

VZL98_01430

CAD:	Curi_c26900

KPAR:

JL105_11335

TIS:	P3962_10695

TIZ:	RBU61_00245

MHG:

MFUN:

SACV:

PFAC:

TSG:	HLK68_08065 HLK68_10945 HLK68_10950

TBB:	J0J69_11525

MCD:

MCRO_0020

MANS:

FRW55_01220

MTUY:

H3143_02225

SCR:	SCHRY_v1c04970(eta) SCHRY_v1c09990

SSYR:

SSYRP_v1c05470(eta) SSYRP_v1c09900

SAPI:

SAPIS_v1c06630(eta)

SERI:

SERIO_v1c06050 SERIO_v1c12170

STUR:

STURON_00734

SFZ:	SFLOR_v1c01370

MMOA:

V5E84_02485

MFR:

MFE_06820

MFM:	MfeM64YM_0824

MFP:

MANI:

MCLO:

MGA:

MGH:

MGF:

MGN:	HFMG06NCA_3405

MGS:	HFMG95NCA_3421

MGT:	HFMG01NYA_3483

MGV:	HFMG94VAA_3494

MGW:	HFMG01WIA_3343

MGAC:

MGAN:

MGNC:

MGZ:

MPE:	MYPE2190(MYPE2190)

MIW:	EER00_02765

APV:

Apar_1208

ATB:	J4859_14200

TIO:	INP52_07400

ELE:

Elen_0220

EYY:	EGYY_02260(TehA)

EGD:	GS424_001255

AEQ:

AEQU_1871

AHAT:

ADCFC_21340

BWA:	HLV38_04980

RTS:	CE91St31_00810

BAQK:

QN215_04680

BFK:	QN062_02480

PPIO:

CE91St28_24860

PYY:	RAH42_00680

FVA:	FV113G1_17360

FUL:	C4N20_08030 C4N20_13550

FMO:	C4N19_00705 C4N19_10985

CSOM:

MKD34_01060 MKD34_09255 MKD34_11125

LEO:	AMK43_09495

LGO:	JCM16774_2015

METB:

AW729_01995 AW729_05010

MEIS:

PXD04_05865 PXD04_09135

MRU:

MEB:

MMIL:

MEYE:

MOL:

MEAR:

LOKI:

Reference

PMID:12635926

Authors

Alouf JE, Muller-Alouf H.

Title

Staphylococcal and streptococcal superantigens: molecular, biological and clinical aspects.

Journal

Int J Med Microbiol 292:429-40 (2003)
DOI:10.1078/1438-4221-00232

Reference

PMID:12228315

Authors

Yamaguchi T, Nishifuji K, Sasaki M, Fudaba Y, Aepfelbacher M, Takata T, Ohara M, Komatsuzawa H, Amagai M, Sugai M

Title

Identification of the Staphylococcus aureus etd pathogenicity island which encodes a novel exfoliative toxin, ETD, and EDIN-B.

Journal

Infect Immun 70:5835-45 (2002)
DOI:10.1128/IAI.70.10.5835-5845.2002

Reference

PMID:21282415

Authors

Kato F, Kadomoto N, Iwamoto Y, Bunai K, Komatsuzawa H, Sugai M

Title

Regulatory mechanism for exfoliative toxin production in Staphylococcus aureus.

Journal

Infect Immun 79:1660-70 (2011)
DOI:10.1128/IAI.00872-10

Sequence

[sae:NWMN_1082]

All links

Ontology (2)   
   TC (1)   
   COG (1)   
Gene (3307)   
   MGENES (3191)   
   RefGene (101)   
   OC (15)   
All databases (3309)   

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