KEGG ORTHOLOGY: K11125

ORTHOLOGY: K11125

Entry

K11125                      KO

Symbol

SMG5, EST1B

Name

protein SMG5

Pathway

map03015

mRNA surveillance pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    K11125  SMG5, EST1B; protein SMG5
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K11125  SMG5, EST1B; protein SMG5
   03032 DNA replication proteins
    K11125  SMG5, EST1B; protein SMG5
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Other surveillance factors
     K11125  SMG5, EST1B; protein SMG5
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     K11125  SMG5, EST1B; protein SMG5
DNA replication proteins [BR:ko03032]
Eukaryotic type
  DNA Replication Termination Factors
   Telomerase complex (animals)
    K11125  SMG5, EST1B; protein SMG5

Genes

HSA:	23381(SMG5)

PTR:	107968716(SMG5)

PPS:	100975351(SMG5)

GGO:	101145357(SMG5)

PON:	100460316(SMG5)

PPYG:

129032459(SMG5)

NLE:	100604174(SMG5)

HMH:	116469266(SMG5)

SSYN:

134734417(SMG5)

MCC:	719446(SMG5)

MCF:	102117185(SMG5)

MTHB:

126933188

MNI:	105498044(SMG5)

CSAB:

103223845(SMG5)

CATY:

105594509(SMG5)

PANU:

101003323(SMG5)

TGE:	112620251(SMG5)

MLEU:

105548639(SMG5)

RRO:	104664922(SMG5)

RBB:	108515513(SMG5)

TFN:	117074261(SMG5)

PTEH:

111543783(SMG5)

CANG:

105502133(SMG5)

CJC:	100403998(SMG5)

SBQ:	101053903(SMG5)

CIMI:

108290223(SMG5)

ANAN:

105715449(SMG5)

CSYR:

103261519(SMG5)

MMUR:

105873135(SMG5)

LCAT:

123634093(SMG5)

PCOQ:

105821804(SMG5)

OGA:	100948536(SMG5)

MMU:	229512(Smg5)

MCAL:

110290762(Smg5)

MPAH:

110319882(Smg5)

RNO:	314915(Smg5l1) 681012(Smg5)

MCOC:

116081431 116093121(Smg5)

ANU:	117706879(Smg5) 117718776

MUN:	110548968(Smg5) 110566038

CGE:	100762914(Smg5) 113837422

MAUA:

101825857(Smg5) 101835943

PROB:

127233034(Smg5) 127235343

PLEU:

114692261(Smg5)

MORG:

121437624 121450530(Smg5)

MFOT:

126514224 126516147

AAMP:

119800636(Smg5)

NGI:	103748743 103750521(Smg5)

HGL:	101709860(Smg5)

CPOC:

100722374(Smg5)

CCAN:

109690468(Smg5)

DORD:

105996525(Smg5)

DSP:	122102478 122109339(Smg5)

PLOP:

125359065(Smg5) 125360938

NCAR:

124979223 124991025

MMMA:

107142769 107156689(Smg5)

OCU:

100341361

OPI:	101519940(SMG5)

TUP:	102481851(SMG5)

GVR:	103588811(SMG5)

CFA:	490414(SMG5)

CLUD:

112648898(SMG5)

VVP:	112918944(SMG5)

VLG:	121485416(SMG5)

NPO:	129508799(SMG5)

AML:	100470386(SMG5)

UMR:	103668687(SMG5)

UAH:	113245240(SMG5)

UAR:	123783392(SMG5)

ELK:	111138843 111139069

LLV:

125085847

MPUF:

101681345(SMG5)

MNP:	132025861(SMG5)

MLK:	131814744(SMG5)

NVS:	122918294(SMG5)

ORO:	101381273(SMG5)

EJU:	114198577(SMG5)

ZCA:	113932171(SMG5)

MLX:	118013904(SMG5)

NSU:	110573546(SMG5)

LWW:	102731374(SMG5)

FCA:	101085434(SMG5)

PYU:	121015600(SMG5)

PCOO:

112851690(SMG5)

PBG:	122475883(SMG5)

PVIV:

125155735(SMG5)

LRUF:

124521687

PTG:	102966954(SMG5)

PPAD:

109256286(SMG5)

PUC:

125925680

AJU:

106981505

HHV:	120244740(SMG5)

BTA:	513598(SMG5)

BOM:	102282188(SMG5)

BIU:	109553279(SMG5)

BBUB:

102414631 102414866(SMG5)

BBIS:

104987371(SMG5)

CHX:	102174524(SMG5)

OAS:	101102770(SMG5) 101121611

BTAX:

128044991(SMG5) 128059199

ODA:	120855695(SMG5) 120860674 120878825

CCAD:

122432088(SMG5) 122450944

MBEZ:

129541663(SMG5) 129559994

SSC:	100153097(SMG5)

CFR:	102511910(SMG5)

CBAI:

105068233(SMG5)

CDK:	105105651(SMG5)

VPC:	102535788(SMG5)

BACU:

103005688(SMG5)

BMUS:

118890336(SMG5)

LVE:	103078668(SMG5)

OOR:	101280460(SMG5)

DLE:	111167119(SMG5)

PCAD:

102974695(SMG5)

PSIU:

116745017(SMG5)

NASI:

112401743(SMG5)

ECB:	100057746(SMG5)

EPZ:	103548826(SMG5)

EAI:	106828466(SMG5)

MYB:	102240128(SMG5)

MYD:	102764317(SMG5)

MMYO:

118673197(SMG5)

MLF:	102439570(SMG5)

MDT:	132221330(SMG5)

PKL:	118721419(SMG5)

EFUS:

103298867(SMG5)

MNA:	107543861(SMG5)

DRO:	112317175(SMG5)

AJM:	119039759(SMG5)

PDIC:

114488741(SMG5)

PHAS:

123804431(SMG5)

MMF:	118637904(SMG5)

PPAM:

129062358(SMG5)

HAI:	109393394(SMG5)

RFQ:	117014745(SMG5)

PALE:

102895876(SMG5)

PGIG:

120592201(SMG5)

PVP:	105296426(SMG5)

RAY:	107521495(SMG5)

MJV:	108383309(SMG5)

TOD:	119237018(SMG5) 119238683

SARA:

101541911(SMG5)

SETR:

126008715 126020694(SMG5)

LAV:	100670731(SMG5)

TMU:

101343548

ETF:	101646944(SMG5) 101661877

DNM:	101443397(SMG5)

MDO:	100023077(SMG5) 107652046 107652048

GAS:	123247808(SMG5)

SHR:	100924141(SMG5) 100926541

AFZ:	127547586 127559778

PCW:	110211921(SMG5)

TVP:	118834778 118846245(SMG5)

OAA:	103168702(SMG5)

GGA:	425473(SMG5)

PCOC:

116238819(SMG5)

MGP:	100542566(SMG5)

CJO:	107324339(SMG5)

TPAI:

128077415

LMUT:

125687466(SMG5)

NMEL:

110387868(SMG5)

APLA:

101798513(SMG5)

ACYG:

106048955(SMG5)

CATA:

118260684(SMG5)

AFUL:

116499764(SMG5)

TGU:	100231729(SMG5)

LSR:	110471507(SMG5)

SCAN:

103824055(SMG5)

PMOA:

120498875(SMG5)

OTC:	121332109(SMG5)

PRUF:

121352164(SMG5)

GFR:	102037461(SMG5)

FAB:

101808181

OMA:	130263200(SMG5)

PHI:	102100693(SMG5)

PMAJ:

107214581(SMG5)

CCAE:

111939455(SMG5)

CBRC:

103611314(SMG5)

ETL:	114069928(SMG5)

ZAB:	102067289(SMG5)

ZLE:	135457716(SMG5)

ACHL:

103799464(SMG5)

SVG:	106863379(SMG5)

MMEA:

130583205(SMG5)

HRT:	120764237(SMG5)

SATI:

136373055(SMG5)

FPG:	101924101(SMG5)

FCH:	102049744(SMG5)

CCRI:

104165891(SMG5)

NNT:	104405960(SMG5)

SHAB:

115602585(SMG5)

ACUN:

113488754

TALA:

104366628(SMG5)

ACHC:

115345876(SMG5)

HALD:

104318930(SMG5)

HLE:	104829669(SMG5)

AGEN:

126040657

GCL:

127026955

LDI:	104352401(SMG5)

MNB:	103778145(SMG5)

AVIT:

104275658(SMG5)

BRHI:

104495525(SMG5)

EGZ:	104123077(SMG5)

NNI:	104012283(SMG5)

PCRI:

104036987(SMG5)

PCAO:

104045057(SMG5)

PADL:

103913895(SMG5)

AFOR:

103902364(SMG5)

FGA:	104080374(SMG5)

GSTE:

104265065

CLV:	102083881(SMG5)

PGUU:

104462493(SMG5)

PLET:

104627293(SMG5)

CMAC:

104476105(SMG5)

CUCA:

104059579(SMG5)

TEO:

104374381

BREG:

104637292(SMG5)

OHA:	104332895(SMG5)

ACAR:

104529663(SMG5)

CPEA:

104386443(SMG5)

CVF:	104292242(SMG5)

RTD:	128900896(SMG5)

AAM:	106492309(SMG5)

AROW:

112969959(SMG5)

NPD:	112953589(SMG5)

TGT:	104579159(SMG5)

DNE:	112990836(SMG5)

SCAM:

104139374(SMG5)

ASN:	102378429(SMG5)

AMJ:	102561317(SMG5)

CPOO:

109323684(SMG5)

GGN:	109295778(SMG5)

PSS:	102445536(SMG5)

CMY:	102936593(SMG5)

CCAY:

125625705(SMG5)

DCC:	119847597(SMG5)

CPIC:

101945960(SMG5)

TST:	117869495(SMG5)

CABI:

116831833(SMG5)

MRV:	120390278(SMG5)

ACS:	100551781 100551844(smg5)

ASAO:

132764060(SMG5)

PVT:	110083745(SMG5)

SUND:

121915456(SMG5)

PBI:	103061764(SMG5)

PMUR:

107296400(SMG5)

CTIG:

120314900(SMG5)

TSR:	106551872(SMG5)

APRI:

131186513(SMG5)

PTEX:

113447435(SMG5)

NSS:	113427839(SMG5) 113429000

VKO:	123032921(SMG5)

PMUA:

114586096(SMG5)

PRAF:

128404179(SMG5)

ZVI:	118075664(SMG5)

HCG:	128337349(SMG5)

GJA:	107110079(SMG5)

STOW:

125442545(SMG5)

EMC:	129337461(SMG5)

XLA:	100137701(smg5.L) 108700391

XTR:	780078(smg5)

NPR:	108795024(SMG5)

RTEM:

120920977(SMG5)

BBUF:

120981404 120981406

BGAR:

122922320(SMG5)

MUO:	115457499(SMG5)

GSH:	117350003(SMG5)

DRE:	553261(smg5)

SRX:	107726659 107728478

SANH:

107671430 107688247

SGH:	107592175 107592453(smg5)

CCAR:

109105035(smg5) 109106256 109106639

CAUA:

113059261 113115735

CGIB:

127974980 128030698

PTET:

122360499(smg5)

LROH:

127178640(smg5)

OMC:	131522158(smg5)

PPRM:

120488123 120488256

RKG:

130079557

MAMB:

125243116(smg5)

CIDE:

127497105

CERY:

137036843(smg5)

MASI:

127453087 127453582

TROS:

130558106(smg5)

TDW:	130432873(smg5)

MANU:

129448652(smg5)

IPU:

108256630

IFU:	128599506(smg5)

PHYP:

113532861(smg5)

SMEO:

124375479(smg5)

TFD:	113649763(smg5)

TVC:	132840587(smg5)

TRN:	134301125(smg5)

AMEX:

103035711(smg5)

CMAO:

118798724(smg5)

EEE:	113571924(smg5)

CHAR:

105891879(smg5)

TRU:	101065130(smg5)

TFS:	130532522(smg5)

TNG:	GSTEN00019522G001

LCO:	104929583(smg5)

NCC:

104955414

TBEN:

117468478(smg5)

CGOB:

115021580(smg5)

PGEO:

117460780(smg5)

GACU:

117543289(smg5)

EMAC:

134862112(smg5)

ELY:	117266033(smg5)

EFO:	125892729(smg5)

PLEP:

121945836(smg5)

SLUC:

116036041(smg5)

ECRA:

117945664(smg5)

ESP:	116691351(smg5)

PFLV:

114557233(smg5)

GAT:	120810203(smg5)

PPUG:

119197937(smg5)

AFB:	129109939(smg5)

CLUM:

117728034(smg5)

PSWI:

130213029(smg5)

MSAM:

119897106(smg5)

SCHU:

122881514(smg5)

CUD:	121513517(smg5)

ALAT:

119005314(smg5)

MZE:

101467053

ONL:	100703796(smg5)

OAU:	116315402(smg5)

OLA:	101173007(smg5)

OML:	112136525(smg5)

CSAI:

133439049(smg5)

XMA:	102231063(smg5)

XCO:	114141773(smg5)

XHE:	116717218(smg5)

PRET:

103477580(smg5)

PFOR:

103150789(smg5)

PLAI:

106954396(smg5)

PMEI:

106919454(smg5)

GAF:	122830486(smg5)

PPRL:

129370981(smg5)

CVG:	107102679(smg5)

CTUL:

119774762(smg5)

GMU:	124865638(smg5)

NFU:	107379147(smg5)

KMR:	108246012(smg5)

ALIM:

106528307(smg5)

NWH:	119409237(smg5)

AOCE:

111577923(smg5)

MCEP:

125015711(smg5)

CSEM:

103388946(smg5)

POV:	109643190(smg5)

SSEN:

122774594(smg5)

HHIP:

117776246(smg5)

HSP:	118113754(smg5)

PPLT:

128449637(smg5)

SMAU:

118284992(smg5)

LCF:

108899466

SDU:	111222624(smg5)

SLAL:

111655678(smg5)

XGL:	120784403(smg5)

HCQ:	109512119(smg5)

SSCV:

125975641

SBIA:

133500410(smg5)

PEE:	133401855(smg5)

PTAO:

133480036(smg5)

BPEC:

110162737(smg5)

MALB:

109965598(smg5)

BSPL:

114843329(smg5)

SJO:	128366645(smg5)

SASA:

106581883 106605282

STRU:

115176903 115178394

OTW:	112222990(smg5) 112229656

OMY:	110487742(smg5) 110515194

OGO:	123997701 124005605

ONE:	115104259 115141107

OKI:	109902058 109908834

OKE:	118364402 118367455

SALP:

111958905 111965135

SNH:	120031166 120048387

CCLU:

121559686(smg5)

ELS:	105019277(smg5)

SFM:	108926799(smg5)

PKI:	111838480(smg5)

AANG:

118236187(smg5)

LOC:

102690973

PSPA:

121306988

ARUT:

117395568 117968257

PSEX:

120528284(smg5)

LCM:	102366362(SMG5)

LERI:

129694515(smg5)

PMRN:

116939998(SMG5)

LRJ:	133346659(SMG5)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

SKO:

DME:	Dmel_CG8954(Smg5)

DER:

6540962

DSE:

6611218

DYA:	Dyak_GE11362

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17401

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119679912 119687214

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006427

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105677059(Smg5)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208050

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

LGLY:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

HHAL:

106685474(Smg5)

NLU:

111062177

PHU:	Phum_PHUM245150

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_305898

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

HAZT:

EAF:

LSM:

DSV:

RSAN:

RMP:

VDE:	111246041 111254553

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136971875(Smg5)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

HRO:	HELRODRAFT_193801

LGI:	LOTGIDRAFT_232390

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_169530

SHX:	MS3_00007514(SMG5_1)

OVI:	T265_06752

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_54089

AQU:

105313034

» show all

Reference

PMID:17053788

Authors

Glavan F, Behm-Ansmant I, Izaurralde E, Conti E

Title

Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex.

Journal

EMBO J 25:5117-25 (2006)
DOI:10.1038/sj.emboj.7601377

Sequence

[hsa:23381]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (1599)   
   KEGG GENES (678)   
   KEGG MGENES (315)   
   RefGene (603)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (1605)   

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