Entry |
|
Symbol |
TYK2
|
Name |
non-receptor tyrosine-protein kinase TYK2 [EC: 2.7.10.2]
|
Pathway |
map04620 | Toll-like receptor signaling pathway |
map04621 | NOD-like receptor signaling pathway |
map04658 | Th1 and Th2 cell differentiation |
map05167 | Kaposi sarcoma-associated herpesvirus infection |
map05168 | Herpes simplex virus 1 infection |
|
Disease |
H00107 | Other well-defined immunodeficiency syndromes |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
04621 NOD-like receptor signaling pathway
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
04658 Th1 and Th2 cell differentiation
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
04659 Th17 cell differentiation
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09158 Development and regeneration
04380 Osteoclast differentiation
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05160 Hepatitis C
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05171 Coronavirus disease - COVID-19
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05164 Influenza A
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05162 Measles
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05168 Herpes simplex virus 1 infection
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05167 Kaposi sarcoma-associated herpesvirus infection
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05169 Epstein-Barr virus infection
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
05165 Human papillomavirus infection
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09174 Infectious disease: parasitic
05145 Toxoplasmosis
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
Enzymes [BR:ko01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
Protein kinases [BR:ko01001]
Non-receptor tyrosine kinases
JAK family [OT]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2
|
Other DBs |
|
Genes |
» show all
|
Reference |
|
Authors |
Firmbach-Kraft I, Byers M, Shows T, Dalla-Favera R, Krolewski JJ |
Title |
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. |
Journal |
Oncogene 5:1329-36 (1990) |
Sequence |
|
Reference |
|
Authors |
Colamonici O, Yan H, Domanski P, Handa R, Smalley D, Mullersman J, Witte M, Krishnan K, Krolewski J |
Title |
Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. |
Journal |
|