KEGG   ORTHOLOGY: K11220
Entry
K11220                      KO                                     
Symbol
STAT1
Name
signal transducer and activator of transcription 1
Pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05140  Leishmaniasis
map05145  Toxoplasmosis
map05152  Tuberculosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05212  Pancreatic cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H01109  Chronic mucocutaneous candidiasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04625 C-type lectin receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04935 Growth hormone synthesis, secretion and action
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05171 Coronavirus disease - COVID-19
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex virus 1 infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05169 Epstein-Barr virus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11220  STAT1; signal transducer and activator of transcription 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
Genes
HSA: 6772(STAT1)
PTR: 459834(STAT1)
PPS: 100971620(STAT1)
GGO: 101131770(STAT1)
PON: 100173683(STAT1)
PPYG: 129031864(STAT1)
NLE: 100596344(STAT1)
HMH: 116810529(STAT1)
SSYN: 129488190(STAT1)
MCC: 693650(STAT1)
MCF: 101925134(STAT1)
MTHB: 126932637
MNI: 105468204(STAT1)
CSAB: 103217529(STAT1)
CATY: 105579958(STAT1)
PANU: 101005886(STAT1)
TGE: 112635950(STAT1)
MLEU: 105535217(STAT1)
RRO: 104675282(STAT1)
RBB: 108527866(STAT1)
TFN: 117094713(STAT1)
PTEH: 111546340(STAT1)
CANG: 105507777(STAT1)
CJC: 100401630(STAT1)
SBQ: 101030811(STAT1)
CIMI: 108284049(STAT1)
ANAN: 105710132(STAT1)
CSYR: 103256404(STAT1)
MMUR: 105877906(STAT1)
LCAT: 123643619(STAT1)
PCOQ: 105813290(STAT1)
OGA: 100956762(STAT1)
MMU: 20846(Stat1)
MCAL: 110304843(Stat1)
MPAH: 110321139(Stat1)
RNO: 25124(Stat1)
MCOC: 116088407(Stat1)
ANU: 117705244(Stat1)
MUN: 110552020(Stat1)
CGE: 100755609(Stat1)
MAUA: 101827798(Stat1)
PROB: 127226208(Stat1)
PLEU: 114705035(Stat1)
MORG: 121442179 121458866
MFOT: 126511873
AAMP: 119803912(Stat1)
NGI: 103736156(Stat1)
HGL: 101718902(Stat1)
CPOC: 100724708(Stat1)
CCAN: 109679865 109682738(Stat1)
DORD: 105995197(Stat1)
DSP: 122115055(Stat1)
PLOP: 125350458(Stat1)
NCAR: 124979200
MMMA: 107138551(Stat1)
OCU: 100343893 127488928
OPI: 101525476(STAT1)
TUP: 102476590(STAT1)
GVR: 103588074(STAT1)
CFA: 488449(STAT1)
CLUD: 112656324(STAT1)
VVP: 112922923(STAT1)
VLG: 121480638(STAT1)
NPO: 129522804(STAT1)
AML: 100474026(STAT1)
UMR: 103659933(STAT1)
UAH: 113250654(STAT1)
UAR: 123798145(STAT1)
ELK: 111144592
LLV: 125095018
MPUF: 101686596(STAT1)
MNP: 132013398(STAT1)
MLK: 131827656(STAT1)
NVS: 122902129(STAT1)
ORO: 101378785(STAT1)
EJU: 114223921(STAT1)
ZCA: 113919574(STAT1)
MLX: 118012204(STAT1)
NSU: 110592138(STAT1)
LWW: 102731818(STAT1)
FCA: 101084561(STAT1)
PYU: 121030838(STAT1)
PCOO: 112869860(STAT1)
PBG: 122481579(STAT1)
PVIV: 125173414(STAT1)
LRUF: 124515343
PTG: 102953174(STAT1)
PPAD: 109274693(STAT1)
PUC: 125911435
AJU: 106979712
HHV: 120233455(STAT1)
BTA: 510814(STAT1)
BOM: 102283508(STAT1)
BIU: 109568771(STAT1)
BBUB: 102415500(STAT1)
BBIS: 105003595(STAT1)
CHX: 102189170(STAT1)
OAS: 100307049(STAT1)
BTAX: 128071221(STAT1)
ODA: 120854684(STAT1)
CCAD: 122426277(STAT1)
MBEZ: 129537915(STAT1)
SSC: 396655(STAT1)
CFR: 102509999(STAT1)
CBAI: 105063982(STAT1)
CDK: 105088783(STAT1)
VPC: 102544679(STAT1)
BACU: 103013781
BMUS: 118898022(STAT1)
LVE: 103069117
OOR: 101272458(STAT1)
DLE: 111171663(STAT1)
PCAD: 102977655(STAT1)
PSIU: 116757187(STAT1)
NASI: 112392137(STAT1)
ECB: 100069633(STAT1)
EPZ: 103548655(STAT1)
EAI: 106828796(STAT1)
MYB: 102243651(STAT1)
MYD: 102757059(STAT1)
MMYO: 118661220(STAT1)
MLF: 102424662(STAT1)
MDT: 132238061(STAT1)
PKL: 118709492(STAT1)
EFUS: 103290572(STAT1)
MNA: 107540521(STAT1)
DRO: 112307780(STAT1)
SHON: 118985299(STAT1)
AJM: 119062093(STAT1)
PDIC: 114494120(STAT1)
PHAS: 123816523(STAT1)
MMF: 118625659(STAT1)
PPAM: 129065467(STAT1)
HAI: 109393276(STAT1)
RFQ: 117025725(STAT1)
PALE: 102886603(STAT1)
PGIG: 120587473(STAT1)
PVP: 105289309(STAT1)
RAY: 107519182(STAT1)
MJV: 108400080(STAT1)
TOD: 119256041(STAT1)
SARA: 101554357(STAT1)
SETR: 126009005(STAT1)
LAV: 100668424(STAT1)
TMU: 101357916
ETF: 101650838(STAT1)
DNM: 101436399(STAT1)
MDO: 100028917(STAT1)
GAS: 123242151(STAT1)
SHR: 105749862(STAT1)
AFZ: 127554459
PCW: 110213248(STAT1)
TVP: 118836098(STAT1)
OAA: 100087266(STAT1)
GGA: 424044(STAT1)
PCOC: 116235961(STAT1)
MGP: 100544816(STAT1)
CJO: 107316322(STAT1)
TPAI: 128077102(STAT1)
LMUT: 125697226(STAT1)
NMEL: 110399457(STAT1)
APLA: 101795022(STAT1)
ACYG: 106039967(STAT1)
CATA: 118261546(STAT1)
AFUL: 116490500(STAT1)
TGU: 100221342(STAT1)
LSR: 110471109(STAT1)
SCAN: 103814539(STAT1)
PMOA: 120511477(STAT1)
OTC: 121335389(STAT1)
PRUF: 121364380(STAT1)
GFR: 102036007(STAT1)
FAB: 101811260(STAT1)
OMA: 130255273(STAT1)
PHI: 102100816(STAT1)
PMAJ: 107207405(STAT1)
CCAE: 111931930(STAT1)
CCW: 104693738(STAT1)
CBRC: 103612443(STAT1)
ETL: 114057449(STAT1)
ZAB: 102075199(STAT1)
ZLE: 135450153(STAT1)
ACHL: 103800628(STAT1)
SVG: 106855910(STAT1)
MMEA: 130578196(STAT1)
HRT: 120755497(STAT1)
SATI: 136363364(STAT1)
FPG: 101922205(STAT1)
FCH: 102054689(STAT1)
CCRI: 104167043(STAT1)
NNT: 104413420(STAT1)
SHAB: 115608872(STAT1)
ACUN: 113482458(STAT1)
TALA: 104362790(STAT1)
ACHC: 115342511(STAT1)
HALD: 104324347(STAT1)
HLE: 104829588(STAT1)
AGEN: 126042725
GCL: 127018115
CSTI: 104560273(STAT1)
LDI: 104351582(STAT1)
DPUB: 104309847(STAT1)
BRHI: 104491544(STAT1)
EGZ: 104130544(STAT1)
NNI: 104014274(STAT1)
PCRI: 104024447(STAT1)
PCAO: 104041888(STAT1)
PADL: 103925472(STAT1)
AFOR: 103897147(STAT1)
FGA: 104077124(STAT1)
GSTE: 104259693(STAT1)
CLV: 102098106(STAT1)
MUI: 104544870
PGUU: 104457917(STAT1)
PLET: 104619945(STAT1)
EHS: 104508311(STAT1)
CMAC: 104485862(STAT1)
CUCA: 104058327(STAT1)
TEO: 104381035(STAT1)
BREG: 104643105(STAT1)
OHA: 104328394(STAT1)
ACAR: 104525996(STAT1)
CPEA: 104386613(STAT1)
CVF: 104290959(STAT1)
RTD: 128913182(STAT1)
AAM: 106492439(STAT1)
AROW: 112978333(STAT1)
NPD: 112954430(STAT1)
TGT: 104565536(STAT1)
DNE: 112982588(STAT1)
SCAM: 104143404(STAT1)
ASN: 102374439(STAT1)
AMJ: 102571738(STAT1)
CPOO: 109323031(STAT1)
GGN: 109301851(STAT1)
PSS: 102462741(STAT1)
CMY: 102934663(STAT1)
CCAY: 125644935(STAT1)
DCC: 119863823(STAT1)
CPIC: 101931440(STAT1)
TST: 117884619(STAT1)
CABI: 116815204(STAT1)
MRV: 120374631(STAT1)
ACS: 100558595(stat1)
ASAO: 132778013(STAT1)
PVT: 110083952(STAT1)
SUND: 121935257(STAT1)
PBI: 103060112(STAT1)
PMUR: 107289220(STAT1)
CTIG: 120298332(STAT1)
TSR: 106537889(STAT1)
PGUT: 117672712(STAT1)
APRI: 131201014(STAT1)
PTEX: 113433994(STAT1)
NSS: 113412400(STAT1)
VKO: 123021819(STAT1)
PMUA: 114607449(STAT1)
PRAF: 128399344(STAT1)
ZVI: 118095191(STAT1)
HCG: 128335373(STAT1)
EMC: 129323801(STAT1)
XLA: 108703082(stat1.S) 398324(stat1.L)
XTR: 780397(stat1)
NPR: 108798858(STAT1)
RTEM: 120943691(STAT1)
BBUF: 121008988(STAT1)
BGAR: 122945284(STAT1)
MUO: 115473779(STAT1)
GSH: 117360731(STAT1)
DRE: 30768(stat1a) 368481(stat1b)
SRX: 107714382 107728932 107739326 107754245
SANH: 107653597 107657528(stat1) 107660594 107687870
SGH: 107565020 107586991 107600977 107602152
CCAR: 109046557 109081472 109095780
CAUA: 113039565 113040769 113053015 113064788 113108355 113108356
CGIB: 127942720 127965590 127965593 127987405 128020154
PTET: 122327842(stat1a) 122351700(stat1b)
LROH: 127153806(stat1a) 127170576(stat1b) 127170859
OMC: 131531449(stat1a)
PPRM: 120477609 120477802(stat1b) 120486276(stat1a)
RKG: 130072558(stat1b) 130072594 130100395(stat1a)
MAMB: 125254061(stat1a) 125270612(stat1b)
CIDE: 127519048 127519050 127519975
CERY: 137027661(stat1a)
MASI: 127438039 127438769 127447213 127448086
TROS: 130549106(stat1a) 130555682(stat1b)
TDW: 130427429(stat1b) 130430030(stat1a)
MANU: 129452652 129454249(stat1a)
IPU: 108259490(stat1a) 108266311(stat1b)
IFU: 128602760(stat1a) 128608451(stat1b)
PHYP: 113524282 113526011
SMEO: 124379860(stat1a) 124383399 124383401
TFD: 113651885(stat1a) 113657095(stat1b) 113661254 113661265
TVC: 132838889(stat1a) 132850464 132850466(stat1b)
TRN: 134304237(stat1a) 134324528
AMEX: 103028874(stat1a) 103031000(stat1b)
CMAO: 118801704(stat1a) 118809414 118821121(stat1b)
EEE: 113581352(stat1) 113586831
CHAR: 105905676(stat1a) 105913246 105913247 105913248
TRU: 101068828(stat1) 101079646
TFS: 130522341(stat1a) 130523302
TNG: GSTEN00027249G001 GSTEN00031849G001 GSTEN00033158G001
LCO: 104920795 104926239
NCC: 104949635
TBEN: 117469171 117485957(stat1b) 117499191(stat1a)
CGOB: 115017314 115026732
PGEO: 117441669(stat1a) 117466574
GACU: 117549497 117549793(stat1a)
EMAC: 134861047(stat1a) 134867158
ELY: 117249488 117250238(stat1a)
EFO: 125884694(stat1a) 125899274
PLEP: 121948957 121962658
SLUC: 116043142(stat1b) 116053691(stat1a)
ECRA: 117939468(stat1a) 117953178
ESP: 116674022(stat1) 116698329
PFLV: 114550696 114564150
GAT: 120826627(stat1a) 120834093
PPUG: 119220035(stat1a)
AFB: 129104815 129111532(stat1a)
CLUM: 117741800(stat1a)
PSWI: 130204372 130204505
MSAM: 119884527 119900506(stat1a) 119903420
SCHU: 122871839(stat1a) 122885811
CUD: 121506226(stat1a) 121522933
ALAT: 119015223(stat1a) 119025600
MZE: 101476764(stat1) 101486905
ONL: 100696359(stat1) 100709564
OAU: 116309467 116317095(stat1a)
OLA: 101154761 101158490
OML: 112154777 112156680(stat1a)
CSAI: 133425311(stat1a)
XMA: 102225755 102237914
XCO: 114140546 114148403
XHE: 116715660 116723258
PRET: 103457785(stat1) 103460709
PFOR: 103130104(stat1) 103130271
PLAI: 106942383(stat1) 106951655
PMEI: 106907676 106909973(stat1)
GAF: 122827058(stat1a) 122840006
PPRL: 129356612(stat1a)
CVG: 107080778 107092284(stat1)
CTUL: 119792770
GMU: 124861925(stat1a) 124870924
NFU: 107384662(stat1) 107397172
KMR: 108229342(stat1a) 108250770
ALIM: 106531438(stat1)
NWH: 119419796 119428888(stat1a)
AOCE: 111563285 111572427
MCEP: 125000988(stat1a) 125017356
CSEM: 103389515(stat1) 103392403
POV: 109637376 109640914
SSEN: 122758564 122763091(stat1a)
HHIP: 117754943 117774286(stat1a)
HSP: 118103226 118119965
PPLT: 128430991 128455436
SMAU: 118282950 118318615
LCF: 108873137 108879807 108879808 108897177
SDU: 111218101 111222701(stat1)
SLAL: 111667430 111672441
XGL: 120798154(stat1a) 120801616
HCQ: 109517578 109520194(stat1)
SSCV: 125988268
SBIA: 133505793(stat1a)
PEE: 133402577(stat1a)
PTAO: 133478909(stat1a)
BPEC: 110156119 110156121 110175594(stat1)
MALB: 109955685(stat1)
BSPL: 114845713(stat1a) 114846801
SJO: 128354436(stat1a) 128367733
SASA: 100136558(STAT1) 106586142
STRU: 115156118 115160666 115195984
OTW: 112235369 112244575(stat1b) 112253779 112253897 112253955
OMY: 100136755(stat1-1) 100137016(stat1-2) 110501544(stat1b) 110520020 110527523
OGO: 124007667 124007940 124011634 124043794
ONE: 115108041 115129673 115133971 115133986 115138513
OKI: 109865728 109871062 109890649 109906681
OKE: 118363713 118367154 118370180 118383626 118385792
SALP: 111970963 111973973 111974236 112067758
SNH: 120033389 120051252 120058211 120064425(stat1b)
CCLU: 121536664 121551541(stat1b) 121562465 121562466 121562503 121568070 123481194 123485102
ELS: 105022417 105022492 105022527
SFM: 108924273 108929360
PKI: 111842948 111845415(stat1)
AANG: 118214287 118223245
LOC: 102685821(stat1)
PSPA: 121322145 121322927
ARUT: 117409265 117426624
PSEX: 120522445
LCM: 102353760(STAT1)
CMK: 103176541
RTP: 109920367
CPLA: 122543210 122551254
HOC: 132805837 132817161
LERI: 129698644 129714674
PMRN: 116938726(STAT1)
LRJ: 133345932(STAT1)
 » show all
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (58)   
   KEGG PATHWAY (58)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (1084)   
   KEGG GENES (567)   
   KEGG MGENES (344)   
   RefGene (169)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (1147)   

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KEGG   ORTHOLOGY: K11225
Entry
K11225                      KO                                     
Symbol
STAT6
Name
signal transducer and activator of transcription 6
Pathway
map04217  Necroptosis
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map05161  Hepatitis B
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H01968  Hyper-IgE syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11225  STAT6; signal transducer and activator of transcription 6
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11225  STAT6; signal transducer and activator of transcription 6
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11225  STAT6; signal transducer and activator of transcription 6
   04659 Th17 cell differentiation
    K11225  STAT6; signal transducer and activator of transcription 6
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11225  STAT6; signal transducer and activator of transcription 6
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11225  STAT6; signal transducer and activator of transcription 6
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11225  STAT6; signal transducer and activator of transcription 6
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11225  STAT6; signal transducer and activator of transcription 6
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11225  STAT6; signal transducer and activator of transcription 6
Genes
HSA: 6778(STAT6)
PTR: 100609243(STAT6)
PPS: 129393500(STAT6)
GGO: 101130575(STAT6)
PON: 100173709(STAT6)
PPYG: 129009744(STAT6)
NLE: 100602651(STAT6)
HMH: 116480880(STAT6)
SSYN: 129465587(STAT6)
MCC: 714159(STAT6)
MCF: 102117594(STAT6)
MTHB: 126930369
MNI: 105474118(STAT6)
CSAB: 103238553(STAT6)
CATY: 105587270(STAT6)
PANU: 101023204(STAT6)
TGE: 112634440(STAT6)
MLEU: 105545561(STAT6)
RRO: 104682375(STAT6)
RBB: 108519693(STAT6)
TFN: 117089901(STAT6)
PTEH: 111541819(STAT6)
CANG: 105500517(STAT6)
CJC: 100390285(STAT6)
SBQ: 101029869(STAT6)
CIMI: 108309713(STAT6)
ANAN: 105729076(STAT6)
CSYR: 103267652(STAT6)
MMUR: 105877964(STAT6)
LCAT: 123639619(STAT6)
PCOQ: 105816496(STAT6)
OGA: 100949888(STAT6)
MMU: 20852(Stat6)
MCAL: 110303914(Stat6)
MPAH: 110326351(Stat6)
RNO: 362896(Stat6)
MCOC: 116076456(Stat6)
ANU: 117696860(Stat6)
MUN: 110561573(Stat6)
CGE: 100753838(Stat6)
MAUA: 101832739(Stat6)
PROB: 127215657(Stat6)
PLEU: 114704789(Stat6)
MORG: 121459000(Stat6)
MFOT: 126514738
AAMP: 119803503(Stat6)
NGI: 103742927(Stat6)
HGL: 101725744(Stat6)
CPOC: 100726686(Stat6)
CCAN: 109686109(Stat6)
DORD: 105989022(Stat6)
DSP: 122124035(Stat6)
PLOP: 125362449(Stat6)
NCAR: 124983249
MMMA: 107140146(Stat6)
OCU: 100344264
OPI: 101522542(STAT6)
TUP: 102485633(STAT6)
GVR: 103596102(STAT6)
CFA: 100142679(STAT6)
CLUD: 112677992(STAT6)
VVP: 112922359(STAT6)
VLG: 121490605(STAT6)
NPO: 129511622(STAT6)
AML: 100476198(STAT6)
UMR: 103656427(STAT6)
UAH: 113256394(STAT6)
UAR: 123787227(STAT6)
ELK: 111160115
LLV: 125106707
MPUF: 101676980(STAT6)
MNP: 132019824(STAT6)
MLK: 131838572(STAT6)
NVS: 122891094(STAT6)
ORO: 101375468(STAT6)
EJU: 114214925(STAT6)
ZCA: 113922017(STAT6)
MLX: 118008683(STAT6)
NSU: 110577770(STAT6)
LWW: 102750407(STAT6)
FCA: 101089873(STAT6)
PYU: 121040891(STAT6)
PCOO: 112863244(STAT6)
PBG: 122473799(STAT6)
PVIV: 125171063(STAT6)
LRUF: 124501154
PTG: 102949991(STAT6)
PPAD: 109270360(STAT6)
PUC: 125919230
AJU: 106975851
HHV: 120224867(STAT6)
BTA: 353105(STAT6)
BOM: 102287830(STAT6)
BIU: 109559334(STAT6)
BBUB: 102396265(STAT6)
BBIS: 104988112(STAT6)
CHX: 102180571(STAT6)
OAS: 101102134(STAT6)
BTAX: 128048609(STAT6)
ODA: 120857477(STAT6)
CCAD: 122427229(STAT6)
MBEZ: 129536419(STAT6)
SSC: 100153518(STAT6)
CFR: 102512918(STAT6)
CBAI: 105062116(STAT6)
CDK: 105098305(STAT6)
VPC: 102543450(STAT6)
BACU: 103012026(STAT6)
BMUS: 118901927(STAT6)
LVE: 103073908(STAT6)
OOR: 101273788(STAT6)
DLE: 111173850(STAT6)
PCAD: 102974661(STAT6)
PSIU: 116760337(STAT6)
NASI: 112394079(STAT6)
ECB: 100050053(STAT6)
EPZ: 103564680(STAT6)
EAI: 106832991(STAT6)
MYB: 102251654(STAT6)
MYD: 102768984(STAT6)
MMYO: 118650227(STAT6)
MLF: 102419724(STAT6)
MDT: 132227790(STAT6)
PKL: 118728907(STAT6)
EFUS: 103292452(STAT6)
MNA: 107546227(STAT6)
DRO: 112319070(STAT6)
SHON: 118975844(STAT6)
AJM: 119035652(STAT6)
PDIC: 114512701(STAT6)
PHAS: 123812457(STAT6)
MMF: 118623461(STAT6)
PPAM: 129075797(STAT6)
HAI: 109390726(STAT6)
RFQ: 117028404(STAT6)
PALE: 102885160(STAT6)
PGIG: 120604938(STAT6)
PVP: 105302552(STAT6)
RAY: 107501843(STAT6)
MJV: 108385818(STAT6)
TOD: 119248074(STAT6)
SARA: 101554096(STAT6)
SETR: 126022904(STAT6)
LAV: 100675819(STAT6)
TMU: 101343014
ETF: 101655836(STAT6)
DNM: 101445221(STAT6)
MDO: 100012148(STAT6)
GAS: 123248669(STAT6)
SHR: 100930901(STAT6)
AFZ: 127539227
PCW: 110210962(STAT6)
TVP: 118850506(STAT6)
OAA: 103171440(STAT6)
GGA: 100859196(STAT6)
PCOC: 116239819(STAT6)
MGP: 104915970
CJO: 107325840(STAT6)
TPAI: 128071971(STAT6)
LMUT: 125685562(STAT6)
APLA: 101803059(STAT6)
ACYG: 106049011(STAT6)
CATA: 118260162(STAT6)
AFUL: 116500005(STAT6)
TGU: 115491383(STAT6)
LSR: 110477067(STAT6)
SCAN: 103824868(STAT6)
PMOA: 120499443(STAT6)
OTC: 121336768(STAT6)
PRUF: 121356376(STAT6)
GFR: 102038203(STAT6)
FAB: 101813321(STAT6)
OMA: 130265686(STAT6)
PHI: 102101245(STAT6)
PMAJ: 107198609(STAT6)
CCAE: 111940568(STAT6)
CBRC: 103611899(STAT6)
ETL: 114071116(STAT6)
ZAB: 102061927(STAT6)
ZLE: 135459098(STAT6)
ACHL: 103809725(STAT6)
SVG: 106863179(STAT6)
MMEA: 130586338(STAT6)
HRT: 120764449(STAT6)
SATI: 136372711(STAT6)
FPG: 101917515(STAT6)
FCH: 102053621(STAT6)
SHAB: 115618727(STAT6)
TALA: 116962810(STAT6)
ACHC: 115350804(STAT6)
HLE: 104830313(STAT6)
AGEN: 126046397
LDI: 104352079(STAT6)
NNI: 104015924(STAT6)
PADL: 103925445(STAT6)
AFOR: 103901395(STAT6)
CLV: 102085063(STAT6)
PLET: 104625946(STAT6)
CUCA: 104057938(STAT6)
BREG: 104634637(STAT6)
ACAR: 104532565(STAT6)
CPEA: 104397625(STAT6)
CVF: 104294742(STAT6)
RTD: 128901321(STAT6)
AROW: 112972153(STAT6)
NPD: 112954131(STAT6)
TGT: 104565950(STAT6)
DNE: 112990691(STAT6)
ASN: 102371350(STAT6)
AMJ: 102573100(STAT6)
CPOO: 109324382(STAT6)
CMY: 102945894(STAT6)
CCAY: 125627541(STAT6)
DCC: 119845934(STAT6)
CPIC: 101950059(STAT6)
TST: 117888664(STAT6)
CABI: 116827809(STAT6)
MRV: 120391151(STAT6)
ACS: 100552866(stat6)
ASAO: 132767736(STAT6)
PVT: 110070963(STAT6)
SUND: 121921117(STAT6)
PBI: 103048764(STAT6)
PMUR: 107291001(STAT6)
CTIG: 120318290(STAT6)
TSR: 106546346(STAT6)
PGUT: 117666533(STAT6)
APRI: 131190230(STAT6)
PTEX: 113444815(STAT6)
NSS: 113416166(STAT6)
VKO: 123029884(STAT6)
PMUA: 114592918(STAT6)
PRAF: 128404625(STAT6)
ZVI: 118078286(STAT6)
HCG: 128344260(STAT6)
GJA: 107120599(STAT6)
STOW: 125428020(STAT6)
EMC: 129345964(STAT6)
XLA: 108709852 495683(stat6.L)
XTR: 100485184(stat6)
NPR: 108797768(STAT6)
RTEM: 120929478(STAT6)
BBUF: 120996047(STAT6)
BGAR: 122930945(STAT6)
MUO: 115465858(STAT6)
GSH: 117357115(STAT6)
DRE: 337413(stat6)
SRX: 107745457
SANH: 107668551 107695735
SGH: 107570234
CCAR: 109062563
CAUA: 113065461 113070527
CGIB: 127944784 128011339
PTET: 122328439(stat6)
LROH: 127154447(stat6)
OMC: 131532040(stat6)
PPRM: 120462789(stat6)
RKG: 130073265(stat6)
MAMB: 125259594(stat6)
CIDE: 127504671
CERY: 137009641(stat6)
MASI: 127419031 127419602
TROS: 130545193(stat6)
TDW: 130409177(stat6)
MANU: 129430295(stat6) 129430372
IPU: 108275950(stat6)
IFU: 128619767(stat6)
PHYP: 113530443
TFD: 113658120(stat6)
TVC: 132862821(stat6)
TRN: 134333805(stat6)
AMEX: 103043059(stat6)
CMAO: 118822853(stat6)
EEE: 113584434
CHAR: 105897361(stat6)
TRU: 101065277
TFS: 130530121(stat6)
TNG: GSTEN00028133G001
LCO: 104932951
NCC: 104967536
TBEN: 117494171(stat6)
CGOB: 115010621
PGEO: 117449335(stat6)
GACU: 117541899(stat6)
EMAC: 134870978(stat6)
ELY: 117257894(stat6)
EFO: 125891693(stat6)
PLEP: 121946810(stat6)
SLUC: 116039386(stat6)
ECRA: 117947758(stat6)
ESP: 116692035
PFLV: 114558374
GAT: 120829090(stat6)
PPUG: 119222585(stat6)
AFB: 129099759(stat6)
CLUM: 117733194(stat6)
PSWI: 130199274(stat6)
MSAM: 119905506(stat6)
SCHU: 122882359(stat6)
CUD: 121517199(stat6)
ALAT: 119022235(stat6)
MZE: 101470833
ONL: 100704348
OAU: 116325821(stat6)
OLA: 101162184
OML: 112159639(stat6)
CSAI: 133457221(stat6)
XMA: 102234517
XCO: 114144511
XHE: 116726793
PRET: 103467308
PFOR: 103141175
PLAI: 106950871
PMEI: 106914971
GAF: 122837518(stat6)
PPRL: 129372291(stat6)
CVG: 107095156
CTUL: 119782241(stat6)
GMU: 124866562(stat6)
NFU: 107390840
KMR: 108244589(stat6)
ALIM: 106525304
NWH: 119416988(stat6)
AOCE: 111586815
MCEP: 125004954(stat6)
CSEM: 103384626
POV: 109630553
SSEN: 122776656(stat6)
HHIP: 117764203(stat6)
HSP: 118110928(stat6)
PPLT: 128442632(stat6)
SMAU: 118316761(stat6)
LCF: 108876433
SDU: 111219011
SLAL: 111670659
XGL: 120803447(stat6)
HCQ: 109529361
SSCV: 125988890
SBIA: 133492965(stat6)
PEE: 133411304(stat6)
PTAO: 133465066(stat6)
BPEC: 110164555
MALB: 109971031
BSPL: 114858971(stat6)
SJO: 128356825(stat6)
SASA: 106567004
STRU: 115167799
OTW: 112221662(stat6)
OMY: 110491929(stat6)
OGO: 124046126(stat6)
ONE: 115102666
OKI: 109869625
OKE: 118360146(stat6)
SALP: 111976582
SNH: 120060994(stat6)
CCLU: 121537855(stat6) 121545894
ELS: 105023834
SFM: 108918572 108939311
PKI: 111837561(stat6)
AANG: 118207476(stat6)
LOC: 102689106
PSPA: 121309072(stat6)
ARUT: 117401020 117966963
PSEX: 120525178(stat6)
CNS: 116347743
CRG: 105332473
 » show all
Reference
PMID:9782085
  Authors
Patel BK, Keck CL, O'Leary RS, Popescu NC, LaRochelle WJ
  Title
Localization of the human stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors.
  Journal
Genomics 52:192-200 (1998)
DOI:10.1006/geno.1998.5436
  Sequence
[hsa:6778]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (562)   
   KEGG GENES (375)   
   KEGG MGENES (99)   
   RefGene (86)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (580)   

Download RDF
KEGG   ORTHOLOGY: K11221
Entry
K11221                      KO                                     
Symbol
STAT2
Name
signal transducer and activator of transcription 2
Pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04380  Osteoclast differentiation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05164  Influenza A
map05165  Human papillomavirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
Disease
H00840  Pseudo-TORCH syndrome
H02525  Disorders of innate immunity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11221  STAT2; signal transducer and activator of transcription 2
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04621 NOD-like receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04625 C-type lectin receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04062 Chemokine signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11221  STAT2; signal transducer and activator of transcription 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11221  STAT2; signal transducer and activator of transcription 2
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11221  STAT2; signal transducer and activator of transcription 2
   05160 Hepatitis C
    K11221  STAT2; signal transducer and activator of transcription 2
   05171 Coronavirus disease - COVID-19
    K11221  STAT2; signal transducer and activator of transcription 2
   05164 Influenza A
    K11221  STAT2; signal transducer and activator of transcription 2
   05162 Measles
    K11221  STAT2; signal transducer and activator of transcription 2
   05168 Herpes simplex virus 1 infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05169 Epstein-Barr virus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05165 Human papillomavirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11221  STAT2; signal transducer and activator of transcription 2
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11221  STAT2; signal transducer and activator of transcription 2
Genes
HSA: 6773(STAT2)
PTR: 451996(STAT2)
PPS: 100972085(STAT2)
GGO: 101146695(STAT2)
PON: 100452011(STAT2)
PPYG: 129010795(STAT2)
NLE: 100585171(STAT2)
HMH: 116480910(STAT2)
SSYN: 129465186(STAT2)
MCC: 712694(STAT2)
MCF: 102133020(STAT2)
MTHB: 126931203
MNI: 105474140(STAT2)
CSAB: 103238525(STAT2)
CATY: 105587295(STAT2)
PANU: 101011342(STAT2)
TGE: 112634334(STAT2)
MLEU: 105529948(STAT2)
RRO: 104673676(STAT2)
RBB: 108516059(STAT2)
TFN: 117089929(STAT2)
PTEH: 111541846(STAT2)
CANG: 105500610(STAT2)
CJC: 100393190(STAT2)
SBQ: 101029836(STAT2)
CIMI: 108309779(STAT2)
ANAN: 105715955(STAT2)
CSYR: 103258295
MMUR: 105865362(STAT2)
LCAT: 123639648(STAT2)
PCOQ: 105817095(STAT2)
OGA: 100944401(STAT2)
MMU: 20847(Stat2)
MCAL: 110302854(Stat2)
MPAH: 110326622(Stat2)
RNO: 288774(Stat2)
MCOC: 116076236(Stat2)
ANU: 117696619(Stat2)
MUN: 110559388(Stat2)
CGE: 100764772(Stat2)
MAUA: 101830537(Stat2)
PROB: 127215637(Stat2)
PLEU: 114681747(Stat2)
MORG: 121462696(Stat2)
MFOT: 126491990
AAMP: 119803231(Stat2)
NGI: 103746519(Stat2)
HGL: 101707295(Stat2)
CPOC: 100719719(Stat2)
CCAN: 109686120(Stat2)
DORD: 105990116(Stat2)
DSP: 122124118(Stat2)
PLOP: 125362786(Stat2)
NCAR: 124983364
MMMA: 107140168(Stat2)
OCU: 100344467 127491150
OPI: 101536685(STAT2)
TUP: 102477989(STAT2)
GVR: 103594016(STAT2)
CFA: 481111(STAT2)
CLUD: 112678012(STAT2)
VVP: 112922378(STAT2)
VLG: 121491356(STAT2)
NPO: 129511791(STAT2)
AML: 100472167(STAT2)
UMR: 103656206(STAT2)
UAH: 113256419(STAT2)
UAR: 123787247(STAT2)
ELK: 111160141
LLV: 125106747
MPUF: 101690720(STAT2)
MNP: 132019801(STAT2)
MLK: 131838598(STAT2)
NVS: 122891158(STAT2)
ORO: 101368050(STAT2)
EJU: 114214932(STAT2)
ZCA: 113922098(STAT2)
MLX: 118008707(STAT2)
NSU: 110577818(STAT2)
LWW: 102739614(STAT2)
FCA: 101099224(STAT2)
PYU: 121040920(STAT2)
PCOO: 112863559(STAT2)
PBG: 122473765(STAT2)
PVIV: 125170213(STAT2)
LRUF: 124501367
PTG: 102967399(STAT2)
PPAD: 109270329(STAT2)
PUC: 125920249
AJU: 106986878
HHV: 120219936(STAT2)
BTA: 511023(STAT2)
BOM: 102277710(STAT2)
BIU: 109559357(STAT2)
BBUB: 102414314(STAT2)
BBIS: 104988072(STAT2)
CHX: 102190301(STAT2)
OAS: 101108211(STAT2)
BTAX: 128047300(STAT2)
ODA: 120857446(STAT2)
CCAD: 122427313(STAT2)
MBEZ: 129537127(STAT2)
SSC: 396923(STAT2)
CFR: 102510903(STAT2)
CBAI: 105075886(STAT2)
CDK: 105086362(STAT2)
VPC: 102545696(STAT2)
BACU: 103000458(STAT2)
BMUS: 118901552(STAT2)
LVE: 103081732(STAT2)
OOR: 101281591(STAT2)
DLE: 111173869(STAT2)
PCAD: 102981574(STAT2)
PSIU: 116760219(STAT2)
NASI: 112394097(STAT2)
ECB: 100052513(STAT2)
EPZ: 103557548(STAT2)
EAI: 106832955(STAT2)
MYB: 102240965(STAT2)
MYD: 102766233(STAT2)
MMYO: 118651142(STAT2)
MLF: 102430852(STAT2)
MDT: 132227766(STAT2)
PKL: 118729130(STAT2)
EFUS: 103292429(STAT2)
MNA: 107546189(STAT2)
DRO: 112319116(STAT2)
SHON: 118975851(STAT2)
AJM: 119040310(STAT2)
PDIC: 114513273(STAT2)
PHAS: 123812791(STAT2)
MMF: 118623876(STAT2)
PPAM: 129075775(STAT2)
HAI: 109396910(STAT2)
RFQ: 117028885(STAT2)
PALE: 102879640(STAT2)
PGIG: 120604905(STAT2)
PVP: 105302576(STAT2)
RAY: 107521231(STAT2)
MJV: 108402236(STAT2)
TOD: 119248061(STAT2)
SARA: 101550386(STAT2)
SETR: 126022154(STAT2)
LAV: 100656374(STAT2)
TMU: 101348948
ETF: 101661602(STAT2)
DNM: 101423495(STAT2)
GAS: 123250724(STAT2)
SHR: 100933167(STAT2)
AFZ: 127564177
PCW: 110210934(STAT2)
TVP: 118849960(STAT2)
OAA: 100087549(STAT2)
GGA: 100858732(STAT2)
PCOC: 116239827(STAT2)
MGP: 104916177(STAT2)
CJO: 107325845(STAT2)
TPAI: 128071944(STAT2)
LMUT: 125685612(STAT2)
NMEL: 110389141(STAT2)
APLA: 119714613(STAT2)
ACYG: 125181336(STAT2)
CATA: 118260153(STAT2)
AFUL: 116499942(STAT2)
TGU: 105760310
LSR: 110477089(STAT2)
PMOA: 120507567 120513580
OTC: 121337502(STAT2)
PRUF: 121358943(STAT2)
FAB: 101821433
OMA: 130265681(STAT2)
PHI: 102112270(STAT2)
ETL: 114070775(STAT2)
ZLE: 135459115(STAT2)
SVG: 106863158(STAT2)
HRT: 120764444(STAT2)
SATI: 136372778(STAT2)
FPG: 101912561(STAT2)
FCH: 106630923(STAT2)
SHAB: 115618700(STAT2)
TALA: 116963079(STAT2)
ACHC: 115351351(STAT2)
HLE: 104830351(STAT2)
AGEN: 126046516
AFOR: 103899559
RTD: 128903206(STAT2)
AROW: 112974309(STAT2)
NPD: 112955622(STAT2)
DNE: 112996983(STAT2)
ASN: 106721797(STAT2)
AMJ: 102574603(STAT2)
CPOO: 109322912(STAT2)
GGN: 109295410(STAT2)
CMY: 102932386(STAT2)
CCAY: 125627841(STAT2)
DCC: 119845671(STAT2)
CPIC: 101944167(STAT2)
CABI: 116827740(STAT2)
MRV: 120391254(STAT2)
ACS: 103277767(stat2)
ASAO: 132768316(STAT2)
PVT: 110074594(STAT2)
SUND: 121921484(STAT2)
PBI: 103065958(STAT2)
PMUR: 107290900(STAT2)
CTIG: 120305466(STAT2)
TSR: 106544441(STAT2)
PGUT: 117662768(STAT2)
APRI: 131191430(STAT2)
PTEX: 113447314(STAT2)
NSS: 113420192(STAT2)
VKO: 123019034(STAT2)
PMUA: 114586539(STAT2)
PRAF: 128406900(STAT2)
ZVI: 118079505(STAT2)
HCG: 128345788(STAT2)
GJA: 107126172(STAT2)
STOW: 125430031(STAT2)
EMC: 129328133(STAT2)
XLA: 108708573(stat2.L) 108709841(stat2.S)
XTR: 100170174(stat2)
NPR: 108791510
RTEM: 120929512(STAT2)
BBUF: 120996012(STAT2)
BGAR: 122930988(STAT2)
MUO: 115465885(STAT2)
GSH: 117358070(STAT2)
DRE: 565200(stat2)
SRX: 107711071 107733592
SANH: 107667368 107673542
SGH: 107582712 107585138
CCAR: 109081275
CAUA: 113050351 113094065
CGIB: 127960183 128015726
PTET: 122347498(stat2)
LROH: 127166603(stat2)
OMC: 131542395(stat2)
PPRM: 120491376(stat2)
RKG: 130087560(stat2)
MAMB: 125273698(stat2)
CIDE: 127513816
CERY: 137011712(stat2)
MASI: 127445754 127448824
TROS: 130556375(stat2)
TDW: 130424265(stat2)
MANU: 129450296(stat2)
IPU: 108272207(stat2)
IFU: 128614774(stat2)
PHYP: 113545874
SMEO: 124399142(stat2)
TFD: 113660522(stat2)
TVC: 132844152(stat2)
TRN: 134317205(stat2)
AMEX: 103021407(stat2)
CMAO: 118808245(stat2)
EEE: 113567990
CHAR: 105897943(stat2)
TRU: 101071462
TFS: 130524302(stat2)
LCO: 104931961
NCC: 104966838
TBEN: 117489454(stat2)
CGOB: 115007853
PGEO: 117446139(stat2)
GACU: 117551086(stat2)
EMAC: 134883587(stat2)
ELY: 117257067(stat2)
EFO: 125892992(stat2)
PLEP: 121955727(stat2)
SLUC: 116065448(stat2)
ECRA: 117943306(stat2)
ESP: 116688367
PFLV: 114553646
GAT: 120835023(stat2)
PPUG: 119229650(stat2)
AFB: 129106335(stat2)
CLUM: 117730251(stat2)
PSWI: 130207963(stat2)
MSAM: 119886144(stat2)
SCHU: 122867140(stat2)
CUD: 121506826(stat2)
ALAT: 119020489(stat2)
MZE: 101479682
ONL: 100701534
OAU: 116336550(stat2)
OLA: 101173855
OML: 112144620(stat2)
CSAI: 133448749(stat2)
XMA: 102236235
XCO: 114135114
XHE: 116710640
PRET: 103465382
PFOR: 103147660(stat2) 103147661
PLAI: 106954437
PMEI: 106909628 106924395
GAF: 122834731(stat2)
PPRL: 129357678(stat2)
CVG: 107082130
CTUL: 119776668(stat2)
GMU: 124856810(stat2)
NFU: 107385678
KMR: 108235753(stat2)
ALIM: 106518034(stat2)
NWH: 119411927(stat2)
AOCE: 111566617
MCEP: 125006679(stat2)
CSEM: 103385958
POV: 109629253
SSEN: 122768157(stat2)
HHIP: 117761297(stat2)
HSP: 118105504(stat2)
PPLT: 128447619(stat2)
SMAU: 118309014(stat2)
LCF: 108881447(stat2)
SDU: 111221460
SLAL: 111667811
XGL: 120807379(stat2)
HCQ: 109522346
SSCV: 125977770
SBIA: 133507561(stat2)
PEE: 133409336(stat2)
PTAO: 133483313(stat2)
BPEC: 110168365
MALB: 109956049
BSPL: 114855222(stat2)
SJO: 128355051(stat2)
SASA: 100270812(stat2)
STRU: 115207827
OTW: 112217577(stat2)
OMY: 110494323(stat2)
OGO: 124002667(stat2)
ONE: 115143174
OKI: 109895769
OKE: 118388565(stat2)
SALP: 111966796
SNH: 120061182(stat2)
CCLU: 121575263(stat2)
ELS: 105017162
SFM: 108918442
PKI: 111854344
AANG: 118210889(stat2)
LOC: 102698942
PSPA: 121309023(stat2)
ARUT: 117401040 117966965
PSEX: 120524824(stat2)
LCM: 102355078(STAT2)
CMK: 103191066
 » show all
Reference
PMID:1502204
  Authors
Fu XY, Schindler C, Improta T, Aebersold R, Darnell JE Jr
  Title
The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.
  Journal
Proc Natl Acad Sci U S A 89:7840-3 (1992)
DOI:10.1073/pnas.89.16.7840
  Sequence
[hsa:6773]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (34)   
   KEGG PATHWAY (34)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (415)   
   KEGG GENES (359)   
   KEGG MGENES (42)   
   RefGene (12)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (454)   

Download RDF
KEGG   ORTHOLOGY: K11222
Entry
K11222                      KO                                     
Symbol
STAT4
Name
signal transducer and activator of transcription 4
Pathway
map04217  Necroptosis
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map05161  Hepatitis B
map05200  Pathways in cancer
map05321  Inflammatory bowel disease
Disease
H00080  Systemic lupus erythematosus
H01493  Localized Scleroderma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11222  STAT4; signal transducer and activator of transcription 4
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11222  STAT4; signal transducer and activator of transcription 4
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11222  STAT4; signal transducer and activator of transcription 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11222  STAT4; signal transducer and activator of transcription 4
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11222  STAT4; signal transducer and activator of transcription 4
  09163 Immune disease
   05321 Inflammatory bowel disease
    K11222  STAT4; signal transducer and activator of transcription 4
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11222  STAT4; signal transducer and activator of transcription 4
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11222  STAT4; signal transducer and activator of transcription 4
Genes
HSA: 6775(STAT4)
PTR: 100610925(STAT4)
PPS: 100972895(STAT4)
GGO: 101137064(STAT4)
PON: 129054459(STAT4)
PPYG: 129031866(STAT4)
NLE: 100596678(STAT4)
HMH: 116810527(STAT4)
SSYN: 129488194(STAT4)
MCC: 693854(STAT4)
MCF: 101925110(STAT4)
MTHB: 126932635
MNI: 105468202(STAT4)
CSAB: 103217530(STAT4)
CATY: 105580191(STAT4)
PANU: 101007479(STAT4)
TGE: 112635949(STAT4)
MLEU: 105535215(STAT4)
RRO: 104675283(STAT4)
RBB: 108527864(STAT4)
TFN: 117094711(STAT4)
PTEH: 111546394(STAT4)
CANG: 105507775(STAT4)
CJC: 100402355(STAT4)
SBQ: 101030273(STAT4)
CIMI: 108284047(STAT4)
ANAN: 105710136(STAT4)
CSYR: 103255989
MMUR: 105877908(STAT4)
LCAT: 123643618(STAT4)
PCOQ: 105813277(STAT4)
OGA: 100957076(STAT4)
MMU: 20849(Stat4)
MCAL: 110293862(Stat4)
MPAH: 110321473(Stat4)
RNO: 367264(Stat4)
MCOC: 116088411(Stat4)
ANU: 117705420(Stat4)
MUN: 110552026(Stat4)
CGE: 100769249
MAUA: 101828236(Stat4)
PROB: 127226209(Stat4)
PLEU: 114705439(Stat4)
MORG: 121442187 121458897
MFOT: 126511871
AAMP: 119803873(Stat4)
NGI: 103736155(Stat4)
HGL: 101718558(Stat4)
CPOC: 100726892(Stat4)
CCAN: 109682739(Stat4)
DORD: 105996111(Stat4)
DSP: 122115048(Stat4)
PLOP: 125350457(Stat4)
NCAR: 124980984
MMMA: 107138552(Stat4)
OCU: 100344146 127488925
OPI: 101529407(STAT4)
TUP: 102475477(STAT4)
GVR: 103588073(STAT4)
CFA: 478845(STAT4)
CLUD: 112656334(STAT4)
VVP: 112922921(STAT4)
VLG: 121480498(STAT4)
NPO: 129523046(STAT4)
AML: 100471596(STAT4)
UMR: 103659686(STAT4)
UAH: 113250651(STAT4)
UAR: 123798149(STAT4)
ELK: 111141082
LLV: 125095870
MPUF: 101687459(STAT4)
MNP: 132013400(STAT4)
MLK: 131827655(STAT4)
NVS: 122902130(STAT4)
ORO: 101379077(STAT4)
EJU: 114223552(STAT4)
ZCA: 113920911(STAT4)
MLX: 118012203(STAT4)
NSU: 110592072(STAT4)
LWW: 102739329(STAT4)
FCA: 101080650(STAT4)
PYU: 121030839(STAT4)
PCOO: 112868399(STAT4)
PBG: 122481580(STAT4)
PVIV: 125173413(STAT4)
LRUF: 124515342
PTG: 102953648(STAT4)
PPAD: 109274706(STAT4)
PUC: 125911432
AJU: 106979739
HHV: 120233461(STAT4)
BTA: 515988(STAT4)
BOM: 102283979(STAT4)
BIU: 109575487(STAT4)
BBUB: 102414384(STAT4)
BBIS: 105003594(STAT4)
CHX: 102189443(STAT4)
OAS: 101117562(STAT4)
BTAX: 128066701(STAT4)
ODA: 120854683(STAT4)
CCAD: 122426650(STAT4)
MBEZ: 129538285(STAT4)
SSC: 397261(STAT4)
CFR: 102509760(STAT4)
CBAI: 105063980(STAT4)
CDK: 105088786(STAT4)
VPC: 102544953(STAT4)
BACU: 103013312(STAT4)
BMUS: 118898551(STAT4)
LVE: 103068832(STAT4)
OOR: 101272876(STAT4)
DLE: 111171668(STAT4)
PCAD: 102977366(STAT4)
PSIU: 116757074(STAT4)
NASI: 112392136(STAT4)
ECB: 100054693(STAT4)
EPZ: 103548657(STAT4)
EAI: 106828795(STAT4)
MYB: 102244347(STAT4)
MYD: 102757535(STAT4)
MMYO: 118661772(STAT4)
MLF: 102424971(STAT4)
MDT: 132238059(STAT4)
PKL: 118709760(STAT4)
EFUS: 103290571(STAT4)
MNA: 107540906(STAT4)
DRO: 112307984(STAT4)
SHON: 118985298(STAT4)
AJM: 119062106(STAT4)
PDIC: 114494417(STAT4)
PHAS: 123831244(STAT4)
MMF: 118625631(STAT4)
PPAM: 129065442(STAT4)
RFQ: 117025897(STAT4)
PALE: 102886854(STAT4)
PGIG: 120587476(STAT4)
PVP: 105289302(STAT4)
RAY: 107519219(STAT4)
MJV: 108400081(STAT4)
TOD: 119256042(STAT4)
SARA: 101554621(STAT4)
SETR: 126008918(STAT4)
LAV: 100668145(STAT4)
TMU: 101351364
ETF: 101651148(STAT4)
DNM: 101435559(STAT4)
MDO: 100617910(STAT4)
GAS: 123239192(STAT4)
SHR: 100933645(STAT4)
AFZ: 127554458
PCW: 110213328(STAT4)
TVP: 118837836(STAT4)
OAA: 100680834(STAT4)
GGA: 768406(STAT4)
PCOC: 116235962(STAT4)
MGP: 100544968(STAT4)
CJO: 107316323(STAT4)
TPAI: 128077103(STAT4)
LMUT: 125696993(STAT4)
NMEL: 110399458(STAT4)
APLA: 101794819(STAT4)
ACYG: 106039968(STAT4)
CATA: 118261542(STAT4)
AFUL: 116490742(STAT4)
TGU: 100224258(STAT4)
LSR: 110471108(STAT4)
SCAN: 103814538(STAT4)
PMOA: 120511478(STAT4)
OTC: 121335323(STAT4)
PRUF: 121364369(STAT4)
GFR: 102035832(STAT4)
FAB: 101811067(STAT4)
OMA: 130255733(STAT4)
PHI: 102100630(STAT4)
PMAJ: 107207703(STAT4)
CCAE: 111931931(STAT4)
CCW: 104693739(STAT4)
CBRC: 103612432(STAT4)
ETL: 114057452(STAT4)
ZAB: 102075479(STAT4)
ZLE: 135450154(STAT4)
ACHL: 103801734(STAT4)
SVG: 106855937(STAT4)
MMEA: 130578197(STAT4)
HRT: 120755499(STAT4)
SATI: 136363362(STAT4)
FPG: 101922376(STAT4)
FCH: 102054863(STAT4)
CCRI: 104168560(STAT4)
NNT: 104399491(STAT4)
SHAB: 115608874(STAT4)
ACUN: 113482457(STAT4)
TALA: 104359993(STAT4)
ACHC: 115342510(STAT4)
HALD: 104321135(STAT4)
HLE: 104829610(STAT4)
AGEN: 126042753
GCL: 127018116
CSTI: 104553565(STAT4)
LDI: 104340450(STAT4)
MNB: 103782407(STAT4)
DPUB: 104309848(STAT4)
AVIT: 104279797(STAT4)
BRHI: 104500824(STAT4)
EGZ: 104130543(STAT4)
NNI: 104014266(STAT4)
PCRI: 104023784(STAT4)
PCAO: 104039651(STAT4)
PADL: 103925471(STAT4)
AFOR: 103897148(STAT4)
FGA: 104075350(STAT4)
GSTE: 104250746(STAT4)
CLV: 102097927(STAT4)
MUI: 104545319(STAT4)
PGUU: 104465139(STAT4)
PLET: 104614061(STAT4)
EHS: 104503240(STAT4)
CMAC: 104478179(STAT4)
CUCA: 104058326(STAT4)
TEO: 104381472(STAT4)
BREG: 104642563(STAT4)
OHA: 104328393(STAT4)
ACAR: 104518025(STAT4)
CPEA: 104386614(STAT4)
CVF: 104290960(STAT4)
RTD: 128912908(STAT4)
AAM: 106492457(STAT4)
AROW: 112978337(STAT4)
NPD: 112955364(STAT4)
TGT: 104565535(STAT4)
DNE: 112982903(STAT4)
SCAM: 104143405(STAT4)
ASN: 102377767(STAT4) 102380863
AMJ: 102571515(STAT4)
CPOO: 109323158(STAT4)
GGN: 109301853(STAT4)
PSS: 102463308(STAT4)
CMY: 102934439(STAT4)
CCAY: 125645003(STAT4)
DCC: 119863417(STAT4)
CPIC: 101932470(STAT4)
TST: 117885060(STAT4)
CABI: 116815205(STAT4)
MRV: 120374670(STAT4)
ACS: 100556501(stat4)
ASAO: 132778057(STAT4)
PVT: 110083962(STAT4)
SUND: 121919723(STAT4)
PBI: 103060923(STAT4)
PMUR: 107289221(STAT4)
CTIG: 120298335(STAT4)
TSR: 106537874(STAT4) 106554672
PGUT: 117672718(STAT4)
APRI: 131201008(STAT4)
PTEX: 113433883(STAT4)
NSS: 113412337(STAT4)
VKO: 123021845(STAT4)
PMUA: 114607458(STAT4)
PRAF: 128399329(STAT4)
ZVI: 118095210(STAT4)
HCG: 128335399(STAT4)
EMC: 129324128(STAT4)
XLA: 108701493(stat4.L)
XTR: 100496013(stat4)
MUO: 115474668(STAT4)
GSH: 117361026(STAT4)
DRE: 368519(stat4)
SRX: 107714380 107728930
SANH: 107657497 107660593
SGH: 107565030(stat4) 107602137
CCAR: 109081475 109096055
CAUA: 113053016 113108357
CGIB: 127965266 128020162
PTET: 122351952(stat4)
LROH: 127171022(stat4)
OMC: 131546438(stat4)
PPRM: 120477614(stat4)
RKG: 130072555(stat4)
MAMB: 125270610(stat4)
CIDE: 127519047
MASI: 127447312 127447993
TROS: 130555683(stat4)
TDW: 130427369(stat4)
IPU: 108266777
IFU: 128608463(stat4)
PHYP: 113525972(stat4)
SMEO: 124382671
TFD: 113657016(stat4)
TVC: 132850465(stat4)
TRN: 134324529(stat4)
AMEX: 103031322(stat4)
CMAO: 118818707(stat4)
EEE: 113581351(stat4)
CHAR: 105913249
TRU: 101068057
TFS: 130523099(stat4)
TNG: GSTEN00033157G001
LCO: 104920796(stat4)
NCC: 104961600
TBEN: 117485647(stat4)
CGOB: 115026731(stat4)
PGEO: 117466514(stat4)
GACU: 117536944(stat4)
EMAC: 134867185(stat4)
ELY: 117251530(stat4)
EFO: 125899276
PLEP: 121948956(stat4)
SLUC: 116043143(stat4)
ECRA: 117952365(stat4)
ESP: 116698332(stat4)
PFLV: 114564065(stat4)
GAT: 120834091(stat4)
PPUG: 119228640(stat4)
AFB: 129105076(stat4)
CLUM: 117750170(stat4)
PSWI: 130200879(stat4)
MSAM: 119903419(stat4)
SCHU: 122885809(stat4)
CUD: 121522543
ALAT: 119025601
MZE: 101482935(stat4)
ONL: 100711701(stat4)
OAU: 116309449(stat4)
OLA: 101161521
OML: 112155517(stat4)
XMA: 102223424(stat4)
XCO: 114148404(stat4)
XHE: 116723259(stat4)
PFOR: 103130255(stat4)
PLAI: 106951656(stat4)
PMEI: 106907678
GAF: 122840007
PPRL: 129355963 129374514
CVG: 107081044
CTUL: 119792759(stat4)
GMU: 124871847
NFU: 107397170(stat4)
KMR: 108250769(stat4)
ALIM: 106530557(stat4)
NWH: 119418980(stat4)
AOCE: 111563280(stat4)
MCEP: 125017357(stat4)
CSEM: 103392405(stat4)
POV: 109637377(stat4)
SSEN: 122758582(stat4)
HHIP: 117755127(stat4)
HSP: 118120298(stat4)
PPLT: 128455913
SMAU: 118282786(stat4)
LCF: 108897211
SDU: 111218102(stat4)
SLAL: 111667431(stat4)
XGL: 120801383(stat4)
HCQ: 109517577(stat4)
SSCV: 125973514
SBIA: 133512529(stat4)
BPEC: 110156165(stat4)
MALB: 109971734
BSPL: 114847246(stat4)
SJO: 128367600(stat4)
SASA: 100380385(stat4) 106586145
STRU: 115156112 115160669
OTW: 112225151(stat4) 112235400
OMY: 110501546(stat4) 110520023
OGO: 124041987 124043796
ONE: 115108086 115138591
OKI: 109865765 109870786
OKE: 118367153 118385955(stat4)
SALP: 111973981 111974244(stat4)
SNH: 120058215 120064424(stat4)
CCLU: 121536667 121551556(stat4)
ELS: 105022416(stat4)
SFM: 108924290 108929374
PKI: 111842925(stat4) 111845442
AANG: 118214570 118223247(stat4)
LOC: 102684153(stat4)
PSPA: 121322144 121323308
ARUT: 117409430 117426897
PSEX: 120522444(stat4)
LCM: 102353506(STAT4)
CMK: 103176542
RTP: 109920378 109926024
CPLA: 122551256
HOC: 132817162
LERI: 129698548
GAE: 121384749
TAD: TRIADDRAFT_53947
 » show all
Reference
PMID:7545930
  Authors
Zhong Z, Wen Z, Darnell JE Jr
  Title
Stat3 and Stat4: members of the family of signal transducers and activators of transcription.
  Journal
Proc Natl Acad Sci U S A 91:4806-10 (1994)
DOI:10.1073/pnas.91.11.4806
  Sequence
[mmu:20849]
Reference
PMID:17216035
  Authors
Lim CP, Cao X
  Title
Structure, function, and regulation of STAT proteins.
  Journal
Mol Biosyst 2:536-50 (2006)
DOI:10.1039/b606246f

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (822)   
   KEGG GENES (416)   
   KEGG MGENES (248)   
   RefGene (155)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (840)   

Download RDF
KEGG   ORTHOLOGY: K11223
Entry
K11223                      KO                                     
Symbol
STAT5A
Name
signal transducer and activator of transcription 5A
Pathway
map04012  ErbB signaling pathway
map04217  Necroptosis
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05207  Chemical carcinogenesis - receptor activation
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05223  Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K11223  STAT5A; signal transducer and activator of transcription 5A
   04630 JAK-STAT signaling pathway
    K11223  STAT5A; signal transducer and activator of transcription 5A
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11223  STAT5A; signal transducer and activator of transcription 5A
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11223  STAT5A; signal transducer and activator of transcription 5A
   04659 Th17 cell differentiation
    K11223  STAT5A; signal transducer and activator of transcription 5A
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11223  STAT5A; signal transducer and activator of transcription 5A
   04935 Growth hormone synthesis, secretion and action
    K11223  STAT5A; signal transducer and activator of transcription 5A
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05207 Chemical carcinogenesis - receptor activation
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05203 Viral carcinogenesis
    K11223  STAT5A; signal transducer and activator of transcription 5A
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05220 Chronic myeloid leukemia
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05223 Non-small cell lung cancer
    K11223  STAT5A; signal transducer and activator of transcription 5A
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05161 Hepatitis B
    K11223  STAT5A; signal transducer and activator of transcription 5A
   05162 Measles
    K11223  STAT5A; signal transducer and activator of transcription 5A
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11223  STAT5A; signal transducer and activator of transcription 5A
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11223  STAT5A; signal transducer and activator of transcription 5A
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11223  STAT5A; signal transducer and activator of transcription 5A
Genes
HSA: 6776(STAT5A)
PTR: 454681(STAT5A)
PPS: 100988550
GGO: 101134686
PON: 100461695
PPYG: 129017271
NLE: 100602815
HMH: 116474862
SSYN: 129469972(STAT5A)
MCC: 574129(STAT5A)
MCF: 102120556
MTHB: 126938428
MNI: 105472122
CSAB: 103243412(STAT5A)
CATY: 105579667(STAT5A)
PANU: 100998364
TGE: 112610117
MLEU: 105552959(STAT5A)
RRO: 104680310(STAT5A)
RBB: 108518319(STAT5A)
TFN: 117066964(STAT5A)
PTEH: 111537370(STAT5A)
CANG: 105503010(STAT5A)
CJC: 100388917(STAT5A)
SBQ: 101049987
CIMI: 108289825(STAT5A)
ANAN: 105711173
CSYR: 103277170
MMUR: 105859421
LCAT: 123620959
PCOQ: 105820251
OGA: 100958999(STAT5A)
MMU: 20850(Stat5a)
MCAL: 110304461
MPAH: 110331871
RNO: 24918(Stat5a)
MCOC: 116078736
ANU: 117710476
MUN: 110550874
CGE: 100755571
MAUA: 101842510
PROB: 127216372
PLEU: 114682811(Stat5a)
MORG: 121442359
MFOT: 126510317
AAMP: 119812127
NGI: 103735895(Stat5a)
CPOC: 100716811
CCAN: 109687323(Stat5a)
DORD: 106003240(Stat5a)
DSP: 122103309
PLOP: 125366352
NCAR: 124980612
MMMA: 107150571(Stat5a)
OCU: 100348518
OPI: 101519331
TUP: 102481444(STAT5A)
GVR: 103595355(STAT5A)
CFA: 490968(STAT5A)
CLUD: 112655519
VVP: 112910775
VLG: 121473588
NPO: 129513286(STAT5A)
AML: 100469683
UMR: 103672571(STAT5A)
UAH: 113265423(STAT5A)
UAR: 123781848
ELK: 111151211
LLV: 125087281
MPUF: 101691575(STAT5A)
MNP: 132004048(STAT5A)
MLK: 131816588(STAT5A)
NVS: 122906197(STAT5A)
ORO: 101372719(STAT5A)
EJU: 114201340
ZCA: 113939059
MLX: 118024912
LWW: 102749241
FCA: 101090913(STAT5A)
PYU: 121045023
PCOO: 112853998
PBG: 122485600
PVIV: 125158438(STAT5A)
LRUF: 124522097
PTG: 102972762(STAT5A)
PPAD: 109258519(STAT5A)
PUC: 125926570
AJU: 106972566
HHV: 120248432
BTA: 282375(STAT5A)
BOM: 102282927(STAT5A)
BIU: 109574089
BBUB: 102415442
BBIS: 104990787
CHX: 102185866
OAS: 443419(STAT5A)
BTAX: 128065012
ODA: 120867072
CCAD: 122441616
MBEZ: 129544422(STAT5A)
SSC: 397550(STAT5A)
CFR: 102520794
CBAI: 105080117(STAT5A)
CDK: 105090457
VPC: 102537862
BACU: 103015475 103020607
BMUS: 118887530
LVE: 103082535(STAT5A)
OOR: 101280792(STAT5A)
DLE: 111166337
PCAD: 102978994
PSIU: 116745691
NASI: 112399148(STAT5A)
ECB: 100052904(STAT5A)
EPZ: 103550390(STAT5A)
EAI: 106826425
MYB: 102240764(STAT5A)
MYD: 102762493(STAT5A)
MMYO: 118671506(STAT5A)
MLF: 102423996(STAT5A)
MDT: 132218650
PKL: 118726601
EFUS: 103293234
MNA: 107528939(STAT5A)
DRO: 112298561
SHON: 118978082
AJM: 119052172(STAT5A)
PDIC: 114503056
PHAS: 123817091
MMF: 118633839
PPAM: 129087067(STAT5A)
HAI: 109395760(STAT5A)
RFQ: 117014072
PALE: 102884638
PGIG: 120611099
PVP: 105306335
RAY: 107513821
TOD: 119230792
SARA: 101552631
SETR: 126016931
LAV: 100672448
TMU: 101343407
ETF: 101661325
DNM: 101443775(STAT5A)
MDO: 100012174(STAT5A)
GAS: 123243791
SHR: 100920045
AFZ: 127560121
PCW: 110198414
TVP: 118846383(STAT5A)
DMK: 116919740
DFR: 124493335
LPOL: 106466022
 » show all
Reference
PMID:7719937
  Authors
Hou J, Schindler U, Henzel WJ, Wong SC, McKnight SL
  Title
Identification and purification of human Stat proteins activated in response to interleukin-2.
  Journal
Immunity 2:321-9 (1995)
DOI:10.1016/1074-7613(95)90140-X
  Sequence
[hsa:6776]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (34)   
   KEGG PATHWAY (34)   
Gene (204)   
   KEGG GENES (154)   
   KEGG MGENES (21)   
   RefGene (25)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (241)   

Download RDF
KEGG   ORTHOLOGY: K04692
Entry
K04692                      KO                                     
Symbol
STAT3
Name
signal transducer and activator of transcription 3
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04217  Necroptosis
map04550  Signaling pathways regulating pluripotency of stem cells
map04630  JAK-STAT signaling pathway
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04920  Adipocytokine signaling pathway
map04931  Insulin resistance
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05145  Toxoplasmosis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05212  Pancreatic cancer
map05221  Acute myeloid leukemia
map05223  Non-small cell lung cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05321  Inflammatory bowel disease
map05417  Lipid and atherosclerosis
Disease
H00016  Oral cancer
H00107  Other well-defined immunodeficiency syndromes
H01968  Hyper-IgE syndrome
H02540  Infantile-onset multisystem autoimmune disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
   04066 HIF-1 signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
   04068 FoxO signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K04692  STAT3; signal transducer and activator of transcription 3
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04692  STAT3; signal transducer and activator of transcription 3
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K04692  STAT3; signal transducer and activator of transcription 3
   04062 Chemokine signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
   04917 Prolactin signaling pathway
    K04692  STAT3; signal transducer and activator of transcription 3
   04935 Growth hormone synthesis, secretion and action
    K04692  STAT3; signal transducer and activator of transcription 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04692  STAT3; signal transducer and activator of transcription 3
   05206 MicroRNAs in cancer
    K04692  STAT3; signal transducer and activator of transcription 3
   05205 Proteoglycans in cancer
    K04692  STAT3; signal transducer and activator of transcription 3
   05207 Chemical carcinogenesis - receptor activation
    K04692  STAT3; signal transducer and activator of transcription 3
   05203 Viral carcinogenesis
    K04692  STAT3; signal transducer and activator of transcription 3
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04692  STAT3; signal transducer and activator of transcription 3
  09162 Cancer: specific types
   05212 Pancreatic cancer
    K04692  STAT3; signal transducer and activator of transcription 3
   05221 Acute myeloid leukemia
    K04692  STAT3; signal transducer and activator of transcription 3
   05223 Non-small cell lung cancer
    K04692  STAT3; signal transducer and activator of transcription 3
  09172 Infectious disease: viral
   05161 Hepatitis B
    K04692  STAT3; signal transducer and activator of transcription 3
   05160 Hepatitis C
    K04692  STAT3; signal transducer and activator of transcription 3
   05171 Coronavirus disease - COVID-19
    K04692  STAT3; signal transducer and activator of transcription 3
   05162 Measles
    K04692  STAT3; signal transducer and activator of transcription 3
   05163 Human cytomegalovirus infection
    K04692  STAT3; signal transducer and activator of transcription 3
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04692  STAT3; signal transducer and activator of transcription 3
   05169 Epstein-Barr virus infection
    K04692  STAT3; signal transducer and activator of transcription 3
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04692  STAT3; signal transducer and activator of transcription 3
  09163 Immune disease
   05321 Inflammatory bowel disease
    K04692  STAT3; signal transducer and activator of transcription 3
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04692  STAT3; signal transducer and activator of transcription 3
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K04692  STAT3; signal transducer and activator of transcription 3
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04692  STAT3; signal transducer and activator of transcription 3
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K04692  STAT3; signal transducer and activator of transcription 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K04692  STAT3; signal transducer and activator of transcription 3
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K04692  STAT3; signal transducer and activator of transcription 3
Genes
HSA: 6774(STAT3)
PTR: 454682(STAT3)
PPS: 100987766(STAT3)
GGO: 101135038(STAT3)
PON: 100171541(STAT3)
PPYG: 129017274(STAT3)
NLE: 100598877(STAT3)
HMH: 116474863(STAT3)
SSYN: 129469416(STAT3)
MCC: 574128(STAT3)
MCF: 102118402(STAT3)
MTHB: 126938424
MNI: 105472413(STAT3)
CSAB: 103243410(STAT3)
CATY: 105579724(STAT3)
PANU: 100998929(STAT3)
TGE: 112608953(STAT3)
MLEU: 105552958(STAT3)
RRO: 104680286(STAT3)
RBB: 108518318(STAT3)
TFN: 117066962(STAT3)
PTEH: 111537369
CANG: 105503009(STAT3)
CJC: 100389282(STAT3)
SBQ: 101049662(STAT3)
CIMI: 108289826(STAT3)
ANAN: 105711264(STAT3)
CSYR: 103267743(STAT3) 103273032 103277171
MMUR: 105859419(STAT3)
LCAT: 123620960(STAT3)
PCOQ: 105820249(STAT3)
OGA: 100958469(STAT3)
MMU: 20848(Stat3)
MCAL: 110306201(Stat3)
MPAH: 110332765(Stat3)
RNO: 25125(Stat3)
MCOC: 116076801(Stat3)
ANU: 117710477(Stat3)
MUN: 110550916(Stat3)
CGE: 100755865(Stat3)
MAUA: 101834358(Stat3)
PROB: 127216384(Stat3)
PLEU: 114682786(Stat3)
MORG: 121442318(Stat3)
MFOT: 126510305
AAMP: 119811206(Stat3)
NGI: 103735896(Stat3)
HGL: 101721899(Stat3)
CPOC: 100717084(Stat3)
CCAN: 109687324(Stat3)
DORD: 106003143(Stat3)
DSP: 122103310(Stat3)
PLOP: 125366353(Stat3)
NCAR: 124978933
MMMA: 107150570(Stat3)
OCU: 100348778
OPI: 101528287(STAT3)
TUP: 102492738(STAT3)
GVR: 103595356
CFA: 490967(STAT3)
CLUD: 112654961(STAT3)
VVP: 112910741(STAT3)
VLG: 121473042(STAT3)
NPO: 129506479(STAT3)
AML: 100469938(STAT3)
UMR: 103672573(STAT3)
UAH: 113265422(STAT3)
UAR: 123781851(STAT3)
ELK: 111151241
LLV: 125086956
MPUF: 101690716(STAT3)
MNP: 132004114(STAT3)
MLK: 131816590(STAT3)
NVS: 122906196(STAT3)
ORO: 101373587(STAT3)
EJU: 114201341(STAT3)
ZCA: 113939486(STAT3)
MLX: 118024910(STAT3)
NSU: 110573316(STAT3)
LWW: 102748936
FCA: 101095698(STAT3)
PYU: 121045024(STAT3)
PCOO: 112853996(STAT3)
PBG: 122485601(STAT3)
PVIV: 125158440(STAT3)
LRUF: 124522098
PTG: 102957987(STAT3)
PPAD: 109258518(STAT3)
PUC: 125926571
AJU: 106972608
HHV: 120248434(STAT3)
BTA: 508541(STAT3)
BOM: 102282282(STAT3)
BIU: 109573817(STAT3)
BBUB: 102414888(STAT3)
BBIS: 104990441(STAT3)
CHX: 102186154(STAT3)
OAS: 100294659(STAT3)
BTAX: 128065049(STAT3)
ODA: 120867076(STAT3)
CCAD: 122441604(STAT3)
MBEZ: 129544425(STAT3) 129549901
SSC: 733648(STAT3)
CFR: 102520228(STAT3)
CBAI: 105080116(STAT3)
CDK: 105090458(STAT3)
VPC: 102541847(STAT3)
BACU: 102997405 103008157(STAT3)
BMUS: 118887532(STAT3)
LVE: 103086495(STAT3)
OOR: 101281369(STAT3)
DLE: 111166491(STAT3)
PCAD: 102976764(STAT3)
PSIU: 116745657(STAT3)
NASI: 112399936(STAT3)
ECB: 100034011(STAT3)
EPZ: 103550364(STAT3)
EAI: 106826327(STAT3)
MYB: 102239853(STAT3)
MYD: 102752037(STAT3)
MMYO: 118671501(STAT3)
MLF: 102422489(STAT3)
MDT: 132218651(STAT3)
PKL: 118726602(STAT3)
EFUS: 103293093(STAT3)
MNA: 107528938(STAT3)
DRO: 112298562(STAT3)
SHON: 118978208(STAT3)
AJM: 119052142(STAT3)
PDIC: 114502756(STAT3)
PHAS: 123816770(STAT3)
MMF: 118634787(STAT3)
PPAM: 129086937(STAT3)
HAI: 109395763(STAT3)
RFQ: 117013100(STAT3)
PALE: 102884374(STAT3)
PGIG: 120611101(STAT3)
PVP: 105306294(STAT3)
RAY: 107513823(STAT3)
MJV: 108386068(STAT3)
TOD: 119232887(STAT3)
SARA: 101552896(STAT3)
SETR: 126020260(STAT3)
LAV: 100669583(STAT3)
TMU: 101342651
ETF: 101656698(STAT3)
DNM: 101444225(STAT3)
MDO: 100011382(STAT3)
GAS: 123246960(STAT3)
SHR: 100933581(STAT3)
AFZ: 127560120
PCW: 110198372(STAT3)
TVP: 118846384(STAT3)
OAA: 100087932(STAT3)
GGA: 420027(STAT3)
PCOC: 116233607(STAT3)
MGP: 100547142(STAT3)
CJO: 107325206(STAT3)
TPAI: 128089012(STAT3)
LMUT: 125684568(STAT3)
NMEL: 110388615(STAT3)
APLA: 101790010(STAT3)
ACYG: 106048026(STAT3)
CATA: 118259131(STAT3)
AFUL: 116498455(STAT3)
TGU: 100219856(STAT3)
LSR: 110471842(STAT3)
SCAN: 103821588(STAT3)
PMOA: 120496658(STAT3)
OTC: 121347603(STAT3)
PRUF: 121351062(STAT3)
GFR: 102036392(STAT3)
FAB: 101809631(STAT3)
OMA: 130263961(STAT3)
PHI: 102101801(STAT3)
PMAJ: 107215123(STAT3)
CCAE: 111939944(STAT3)
CCW: 104697761(STAT3)
CBRC: 103620736(STAT3)
ETL: 114063626(STAT3)
ZAB: 102062617(STAT3)
ZLE: 135458364(STAT3)
ACHL: 103797727(STAT3)
SVG: 106858641(STAT3)
MMEA: 130581462(STAT3)
HRT: 120763700(STAT3)
SATI: 136372158(STAT3)
FPG: 101917971(STAT3)
FCH: 102053408(STAT3)
CCRI: 104165667(STAT3)
SHAB: 115617605(STAT3)
ACUN: 113489073(STAT3)
TALA: 104360535(STAT3)
ACHC: 115344660(STAT3)
HALD: 104314723(STAT3)
HLE: 104842944(STAT3)
AGEN: 126038238
CSTI: 104563631(STAT3)
MNB: 103772403(STAT3)
DPUB: 104309596(STAT3)
BRHI: 104496281(STAT3)
EGZ: 104134824(STAT3)
NNI: 104009927(STAT3)
PCRI: 104027156(STAT3)
PCAO: 104049907(STAT3)
PADL: 103920524(STAT3)
AFOR: 103901821(STAT3)
FGA: 104075266
GSTE: 104262038(STAT3)
CLV: 102090191(STAT3)
MUI: 104541265(STAT3)
PGUU: 104464868(STAT3)
PLET: 104619955(STAT3)
CMAC: 104476015(STAT3)
CUCA: 104054404(STAT3)
TEO: 104372776(STAT3)
BREG: 104635697(STAT3)
OHA: 104332240(STAT3)
ACAR: 104522705(STAT3)
CPEA: 104385656(STAT3)
CVF: 104296000(STAT3)
RTD: 128919143(STAT3)
AAM: 106491102(STAT3)
AROW: 112968719(STAT3)
NPD: 112951799(STAT3)
TGT: 104571861(STAT3)
DNE: 112993847(STAT3)
SCAM: 104143581(STAT3)
ASN: 102381312(STAT3)
AMJ: 102575901(STAT3)
CPOO: 109320366(STAT3)
GGN: 109289716(STAT3)
PSS: 102460388(STAT3)
CMY: 102932633(STAT3)
CCAY: 125626679(STAT3)
DCC: 119848948(STAT3)
CPIC: 101952372(STAT3)
CABI: 116820371(STAT3)
MRV: 120392259(STAT3)
ACS: 100566559(stat3)
ASAO: 132778220(STAT3)
PVT: 110074829(STAT3)
SUND: 121933338(STAT3)
PBI: 103059982(STAT3)
PMUR: 107282651(STAT3)
CTIG: 120309722(STAT3)
TSR: 106541153(STAT3)
PGUT: 117664596(STAT3)
APRI: 131198342(STAT3)
PTEX: 113442956(STAT3)
NSS: 113413521(STAT3)
VKO: 123030484(STAT3)
PMUA: 114581554(STAT3)
PRAF: 128399426(STAT3)
ZVI: 118095339(STAT3)
HCG: 128329793(STAT3)
GJA: 107111493(STAT3)
STOW: 125444653(STAT3)
EMC: 129338257(STAT3)
XLA: 108702458 379264(stat3.2.L) 779100(stat3.1.L)
XTR: 100498278(stat3.1) 100498547(stat3.2)
NPR: 108792989(STAT3)
RTEM: 120918747(STAT3)
BBUF: 121003130(STAT3)
BGAR: 122942396(STAT3)
MUO: 115482291(STAT3)
GSH: 117347191(STAT3)
DRE: 30767(stat3)
SRX: 107731003 107754129
SANH: 107653351 107690299
SGH: 107560746(stat3) 107567623
CCAR: 109047224(stat3) 109080466 109080954
CAUA: 113043394 113046927
CGIB: 127948235 127953596
PTET: 122341743(stat3)
LROH: 127155558(stat3)
OMC: 131536411(stat3)
PPRM: 120489714(stat3)
RKG: 130071199(stat3)
MAMB: 125279525(stat3)
CIDE: 127510137
CERY: 137017486(stat3)
MASI: 127450489 127452371
TROS: 130561427(stat3)
TDW: 130426022(stat3)
MANU: 129436249(stat3)
IPU: 100304658
IFU: 128601899(stat3)
PHYP: 113528081(stat3)
SMEO: 124396762(stat3)
TFD: 113641145(stat3)
TVC: 132861476(stat3)
TRN: 134300168(stat3)
AMEX: 103033344(stat3)
CMAO: 118821460(stat3)
EEE: 113589971(stat3)
CHAR: 105890768(stat3)
TRU: 101070968(stat3)
TFS: 130514622(stat3)
LCO: 104925957(stat3)
TBEN: 117493484(stat3)
CGOB: 115012238(stat3)
PGEO: 117450920(stat3)
GACU: 117548409(stat3)
EMAC: 134877781(stat3)
ELY: 117268499(stat3)
EFO: 125879355(stat3)
PLEP: 121956091(stat3)
SLUC: 116059637(stat3)
ECRA: 117958415(stat3)
ESP: 116702317(stat3)
PFLV: 114569512(stat3)
GAT: 120828237(stat3)
PPUG: 119220174(stat3)
AFB: 129098137(stat3)
CLUM: 117734569(stat3)
PSWI: 130188242(stat3)
MSAM: 119892323(stat3)
SCHU: 122869591(stat3)
CUD: 121529469(stat3)
ALAT: 119013366(stat3)
MZE: 101480689(stat3)
ONL: 100692602(stat3)
OAU: 116312473(stat3)
OLA: 100049477(stat3)
OML: 112146943(stat3)
CSAI: 133422719(stat3)
XMA: 102226045(stat3)
XCO: 114160261(stat3)
XHE: 116735280(stat3)
PRET: 103469403(stat3)
PFOR: 103142203(stat3) 103142204
PLAI: 106963656(stat3)
PMEI: 106904928 106931289(stat3)
GAF: 122821446(stat3)
PPRL: 129373718(stat3)
CVG: 107091797(stat3)
CTUL: 119778878(stat3)
GMU: 124862739 124864363
NFU: 107378443(stat3)
KMR: 108243798(stat3)
ALIM: 106528099(stat3)
NWH: 119421911(stat3)
AOCE: 111576401(stat3)
MCEP: 124997983(stat3)
CSEM: 103393170(stat3)
POV: 109634199(stat3)
SSEN: 122785609(stat3)
HHIP: 117766856(stat3)
HSP: 118122879(stat3)
PPLT: 128458887(stat3)
SMAU: 118289302(stat3)
LCF: 108901193
SDU: 111217480(stat3)
SLAL: 111660433(stat3)
XGL: 120785053(stat3)
HCQ: 109513792(stat3)
SSCV: 125983822
SBIA: 133514559(stat3)
PEE: 133415491(stat3)
PTAO: 133465411(stat3)
BPEC: 110159498(stat3)
MALB: 109964187(stat3)
BSPL: 114860996(stat3)
SJO: 128378375(stat3)
SASA: 106601025 106607297
STRU: 115171116 115179399 115197994
OTW: 112225989 112258660
OMY: 100136756(rbtstat3) 110538194
OGO: 123998591 124015282
ONE: 115104128 115110281
OKI: 109890433 109898422 116374454
OKE: 118365267 118370828
SALP: 111980764 111980873
SNH: 120033139 120034362 120035921
CCLU: 121550542 121569579
ELS: 105013350(stat3)
SFM: 108919563 108941723
PKI: 111842512(stat3) 111856019
AANG: 118216486 118220792(stat3)
LOC: 102697118(stat3)
PSPA: 121301776 121324063
ARUT: 117433411 117435026
PSEX: 120517701(stat3)
LCM: 102365345(STAT3)
CMK: 103189176(stat3)
RTP: 109928447
CPLA: 122539855(stat3)
HOC: 132830988(stat3)
LERI: 129710261(stat3)
PMRN: 116945023
LRJ: 133345387
 » show all
Reference
PMID:10688651
  Authors
Tsai YT, Su YH, Fang SS, Huang TN, Qiu Y, Jou YS, Shih HM, Kung HJ, Chen RH
  Title
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.
  Journal
Mol Cell Biol 20:2043-54 (2000)
DOI:10.1128/MCB.20.6.2043-2054.2000
  Sequence
[hsa:6774]
Reference
PMID:7512451
  Authors
Akira S, Nishio Y, Inoue M, Wang XJ, Wei S, Matsusaka T, Yoshida K, Sudo T, Naruto M, Kishimoto T
  Title
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway.
  Journal
Cell 77:63-71 (1994)
DOI:10.1016/0092-8674(94)90235-6
  Sequence
[hsa:6774]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (64)   
   KEGG PATHWAY (64)   
Disease (4)   
   KEGG DISEASE (4)   
Drug (1)   
   KEGG DRUG (1)   
Gene (908)   
   KEGG GENES (429)   
   KEGG MGENES (214)   
   RefGene (261)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (981)   

Download RDF
KEGG   ORTHOLOGY: K11224
Entry
K11224                      KO                                     
Symbol
STAT5B
Name
signal transducer and activator of transcription 5B
Pathway
map04012  ErbB signaling pathway
map04062  Chemokine signaling pathway
map04217  Necroptosis
map04630  JAK-STAT signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04917  Prolactin signaling pathway
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05207  Chemical carcinogenesis - receptor activation
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05223  Non-small cell lung cancer
Disease
H00931  Growth hormone insensitivity with immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04630 JAK-STAT signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04659 Th17 cell differentiation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04062 Chemokine signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09152 Endocrine system
   04917 Prolactin signaling pathway
    K11224  STAT5B; signal transducer and activator of transcription 5B
   04935 Growth hormone synthesis, secretion and action
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05207 Chemical carcinogenesis - receptor activation
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05203 Viral carcinogenesis
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05220 Chronic myeloid leukemia
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05223 Non-small cell lung cancer
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05161 Hepatitis B
    K11224  STAT5B; signal transducer and activator of transcription 5B
   05162 Measles
    K11224  STAT5B; signal transducer and activator of transcription 5B
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11224  STAT5B; signal transducer and activator of transcription 5B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11224  STAT5B; signal transducer and activator of transcription 5B
Transcription factors [BR:ko03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11224  STAT5B; signal transducer and activator of transcription 5B
Genes
HSA: 6777(STAT5B)
PTR: 454679(STAT5B)
PPS: 100989105
GGO: 101128930
PON: 100462537(STAT5B)
PPYG: 129017272(STAT5B)
NLE: 100602489
HMH: 116474861(STAT5B)
SSYN: 129469974(STAT5B)
MCC: 709760(STAT5B)
MCF: 102127060(STAT5B)
MTHB: 126938430
MNI: 105472124
CSAB: 103243413(STAT5B)
CATY: 105579668(STAT5B)
PANU: 101000002(STAT5B)
TGE: 112610116(STAT5B)
MLEU: 105553080
RRO: 104680321
RBB: 108518352
TFN: 117066965
PTEH: 111537374(STAT5B)
CANG: 105503146
CJC: 100388552(STAT5B)
SBQ: 101043203(STAT5B)
CIMI: 108289827
ANAN: 105711172
CSYR: 103276756
MMUR: 105859420(STAT5B)
LCAT: 123620957(STAT5B)
PCOQ: 105820211
OGA: 100955743
MMU: 20851(Stat5b)
MCAL: 110306026(Stat5b)
MPAH: 110331105(Stat5b)
RNO: 25126(Stat5b)
MCOC: 116078734(Stat5b)
ANU: 117710053
MUN: 110550889
CGE: 100750571
MAUA: 101835654(Stat5b)
PROB: 127216001(Stat5b)
PLEU: 114682785
MORG: 121442319(Stat5b)
MFOT: 126510303
AAMP: 119811038
NGI: 103735893(Stat5b)
HGL: 101722721(Stat5b)
CPOC: 100716532(Stat5b)
CCAN: 109692057
DORD: 106002556(Stat5b)
DSP: 122100261
PLOP: 125365131(Stat5b)
NCAR: 124979870
MMMA: 107150572
OCU: 100348267
OPI: 101518842
TUP: 102492323(STAT5B)
GVR: 103595352
CFA: 490969(STAT5B)
CLUD: 112655520
VVP: 112910740(STAT5B)
VLG: 121472926(STAT5B)
NPO: 129508314
AML: 100479246
UMR: 103672570
UAH: 113265424
UAR: 123781849(STAT5B)
ELK: 111151253
LLV: 125087045
MPUF: 101692423(STAT5B)
MNP: 132004115
MLK: 131815766
NVS: 122906198
ORO: 101372217(STAT5B)
EJU: 114201399(STAT5B)
ZCA: 113939349(STAT5B)
MLX: 118024913(STAT5B)
NSU: 110573273
LWW: 102749665
FCA: 101090663(STAT5B)
PYU: 121045021(STAT5B)
PBG: 122485599(STAT5B)
PVIV: 125158439
LRUF: 124522246
PTG: 102972489(STAT5B)
PPAD: 109258541
PUC: 125926542
AJU: 106972565
HHV: 120248396(STAT5B)
BTA: 282376(STAT5B)
BOM: 102283211(STAT5B)
BIU: 109573773(STAT5B)
BBUB: 102400858
BBIS: 104990788
CHX: 102176415(STAT5B)
OAS: 101122961(STAT5B)
BTAX: 128064838(STAT5B)
ODA: 120867075
CCAD: 122441627
MBEZ: 129544423(STAT5B)
SSC: 397340(STAT5B)
CFR: 102511001(STAT5B)
CBAI: 105080118(STAT5B)
CDK: 105090456
VPC: 102538126
BMUS: 118887531(STAT5B)
LVE: 103082258(STAT5B)
OOR: 101280265(STAT5B)
DLE: 111166483
PCAD: 102994339(STAT5B)
PSIU: 116745059(STAT5B)
NASI: 112399174
ECB: 100052954
EPZ: 103550391
EAI: 106826362(STAT5B)
MYB: 102241062(STAT5B)
MMYO: 118671504
MLF: 102424720
MDT: 132218652(STAT5B)
PKL: 118726604
EFUS: 103293235(STAT5B)
MNA: 107528845
DRO: 112298560(STAT5B)
SHON: 118977990
AJM: 119037510
PDIC: 114502991(STAT5B)
PHAS: 123816875(STAT5B)
MMF: 118634401(STAT5B)
PPAM: 129086955
RFQ: 117014073(STAT5B)
PALE: 102884882
PGIG: 120611100
PVP: 105306336
RAY: 107513822(STAT5B)
MJV: 108388330
TOD: 119232882(STAT5B)
SARA: 101552185(STAT5B)
SETR: 126016963
LAV: 100669299(STAT5B)
TMU: 101354148
ETF: 101661010
DNM: 101419007(STAT5B)
MDO: 100011470(STAT5B)
GAS: 123245349
SHR: 100920307(STAT5B)
AFZ: 127560124
PCW: 110198412
TVP: 118845877
OAA: 100092915(STAT5B)
GGA: 395556(STAT5B)
PCOC: 116233608
MGP: 100546986
CJO: 107325190
TPAI: 128089013
LMUT: 125684570
NMEL: 110388528(STAT5B)
APLA: 101790203
ACYG: 106047991
CATA: 118259130
AFUL: 116498619
TGU: 100222731
LSR: 110471843
SCAN: 103821589
PMOA: 120496657
OTC: 121347621
PRUF: 121351183
GFR: 102036670(STAT5B)
FAB: 101808879(STAT5B)
OMA: 130263959
PHI: 102101483
PMAJ: 107215121
CCAE: 111939998
CCW: 104697815
CBRC: 103620455
ETL: 114063604
ZAB: 102066095
ZLE: 135458505
ACHL: 103804418
SVG: 106858640
MMEA: 130581463
HRT: 120763830
SATI: 136372157
FPG: 101918263(STAT5B)
FCH: 102053699
SHAB: 115617591
TALA: 116960729
ACHC: 115344699
HLE: 104842943
AGEN: 126038674
CSTI: 104560387
DPUB: 104309595
EGZ: 104135093
NNI: 104009926
AFOR: 103902253
CLV: 102098622
CUCA: 104054405
CPEA: 104385702
RTD: 128919233
AROW: 112968721
NPD: 112951852
TGT: 104571860
ASN: 102380420
AMJ: 102575674(STAT5B)
CPOO: 109320364
GGN: 109289127
CMY: 102942063 114022664
CCAY: 125626677 125626678
DCC: 119848910 119849086
CPIC: 101932204
TST: 117870579
CABI: 116820372
MRV: 120392110 120392261
ACS: 100566752(stat5b)
ASAO: 132778223
PVT: 110074911
SUND: 121933099
PBI: 103049078
PMUR: 107282650 107297709 107298083
CTIG: 120309721
TSR: 106541154
PGUT: 117664595
APRI: 131198341
PTEX: 113442826
NSS: 113413518
VKO: 123030656
PMUA: 114583662
PRAF: 128399404
ZVI: 118094191
HCG: 128331647
GJA: 107111494
STOW: 125444644
EMC: 129338434
XLA: 399176(stat5b.L) 414637(stat5b.S)
XTR: 100495240(stat5b)
NPR: 108788932
RTEM: 120918206
BBUF: 121005428
BGAR: 122941072
MUO: 115481497
GSH: 117347194
DRE: 369197(stat5a) 445474(stat5b)
SRX: 107716464 107727963 107729162 107730981 107755555
SANH: 107653267 107674616 107687020 107690298
SGH: 107551841 107556764 107560759 107568282
CCAR: 109049936 109059663 109071022 109074147 109090548
CAUA: 113043382 113046928 113056267 113112125
CGIB: 127948271 127953597 128024903
PTET: 122341745(stat5a) 122355458(stat5b)
LROH: 127155590(stat5a) 127174202(stat5b)
OMC: 131551083(stat5b)
PPRM: 120488720(stat5b) 120489715(stat5a)
RKG: 130071201(stat5a) 130087385(stat5b)
MAMB: 125255293(stat5b) 125279545(stat5a)
CIDE: 127510139 127523584
CERY: 137007419(stat5b)
MASI: 127422911 127450492 127452374
TROS: 130568732(stat5b)
TDW: 130426023(stat5a) 130438645(stat5b)
MANU: 129420458(stat5b) 129436250(stat5a)
IPU: 108273804(stat5b) 108279147(stat5a)
IFU: 128601883(stat5a) 128616839(stat5b)
PHYP: 113528082 113535356
SMEO: 124388956(stat5b) 124396761(stat5a)
TFD: 113652201(stat5a) 113662164(stat5b)
TVC: 132840904(stat5b)
TRN: 134300169(stat5a) 134322030(stat5b)
AMEX: 103033010(stat5a) 103042656(stat5b)
CMAO: 118809132(stat5b) 118821461(stat5a)
EEE: 113581977 113591522
CHAR: 105890767(stat5a) 105910183
TRU: 101071345
TFS: 130514621(stat5a)
TNG: GSTEN00022043G001
LCO: 104925974 104938972
NCC: 104948337 104952122
TBEN: 117473486 117493483(stat5a)
CGOB: 115012237 115024525
PGEO: 117450919(stat5a) 117465138
GACU: 117548821(stat5a) 117560317
EMAC: 134870424 134877780(stat5a)
ELY: 117247445 117268498(stat5a)
EFO: 125879354(stat5a) 125880992
PLEP: 121956090(stat5a) 121958483
SLUC: 116059636(stat5a) 116067487
ECRA: 117936750 117958410(stat5a)
ESP: 116671513 116702316 116704597
PFLV: 114547635 114569511
GAT: 120819248 120828238(stat5a)
PPUG: 119212799 119220165(stat5a)
AFB: 129093133 129098136(stat5a)
CLUM: 117734568(stat5a) 117748445
PSWI: 130188240(stat5a) 130203278
MSAM: 119892306(stat5a) 119916364
SCHU: 122867482 122869589(stat5a)
CUD: 121528063 121529468(stat5a)
ALAT: 119009634 119013365(stat5a)
MZE: 101468393 101485426
ONL: 100690945 100692331
OAU: 116312472(stat5a) 116320031
OLA: 101163082 101168657
OML: 112146942(stat5a) 112162336
CSAI: 133419839 133422721(stat5a)
XMA: 102226876 102235513
XCO: 114150687 114160262
XHE: 116726965 116735725
PRET: 103469404 103482184
PFOR: 103142200 103142484
PLAI: 106936424 106963655
PMEI: 106927210 106931287
GAF: 122821445(stat5a) 122823242
PPRL: 129352275 129373719(stat5a)
CVG: 107087640 107091800
CTUL: 119778879(stat5a) 119796116
GMU: 124862983 124864740 124874677
NFU: 107378442 107396992
KMR: 108243804(stat5a) 108245177
ALIM: 106522102 106528084
NWH: 119421910(stat5a) 119424214
AOCE: 111565177 111576400
MCEP: 124997980(stat5a) 125022426
CSEM: 103381659 103393172
POV: 109627022 109634198
SSEN: 122759289 122785610(stat5a)
HHIP: 117752427 117766855(stat5a)
HSP: 118100442 118122878(stat5a)
PPLT: 128426633 128458886(stat5a)
SMAU: 118287490 118289301(stat5a)
LCF: 108876812 108879315 108901182
SDU: 111217479 111237041
SLAL: 111660431 111664358
XGL: 120785048(stat5a) 120794630
HCQ: 109513793 109529297
SSCV: 125983826 125991783
SBIA: 133495970
PEE: 133415493(stat5a) 133418105
PTAO: 133469605
BPEC: 110154167 110159495
MALB: 109964186 109966669
BSPL: 114845404 114860995(stat5a)
SJO: 128378374(stat5a) 128381015
SASA: 100380532(sta5b) 106579144 106607295
STRU: 115161213 115171115 115198021
OTW: 112223777 112225727 112258659
OMY: 100135887(stat5) 110491683 110538192
OGO: 123998889 124015283 124048425
ONE: 115103495 115106643 115110283
OKI: 109865530 109893324 109897291
OKE: 118364650 118372176 118377919
SALP: 111977867 111980766
SNH: 120034058 120035909 120046299
CCLU: 121550540 121558458 121569580
ELS: 105013349 105027628
SFM: 108919537 108941722
PKI: 111856018
AANG: 118220791(stat5a)
LOC: 102697320(stat5b)
PSPA: 121301711 121324059
ARUT: 117433413 117435028(stat5a)
PSEX: 120518105(stat5a)
LCM: 102348150(STAT5B) 102350580(STAT6)
CMK: 103189177(stat5a)
RTP: 109924857 109929795(stat5a)
CPLA: 122539852(stat5a) 122543209
HOC: 132805836 132830987(stat5a)
LERI: 129710260(stat5a) 129714703
PMRN: 116943942 116945041
LRJ: 133345389 133356808
BFO: 118403966 118417526
BBEL: 109474225 109480543
CIN: 778770(stat-b) 778907
SCLV: 120331175 120343429
SPU: 576433
LPIC: 129255806 129255807
ARUN: 117288577
AJC: 117120872
SKO: 100313741
DME: Dmel_CG4257(Stat92E)
DER: 6553695
DSE: 6619260
DSI: Dsimw501_GD20060(Dsim_GD20060)
DYA: Dyak_GE25067
DSR: 110188679
DPO: 6897369
DPE: 6588035
DMN: 108155914
DWI: 111518517 111518527 26528977 26529701 26530204 6649639
DGR: 6569826
DMO: Dmoj_GI10538
DAZ: 108615391
DNV: 108653502
DHE: 111595033 115483329
DVI: 6629898
CCAT: 101457467 101458360 101458536
BOD: 106617283 106617302 118682699
BDR: 105231837 105231839
RZE: 108365486 108369352 108370198
AOQ: 129240638 129240657
TDA: 119685678
MDE: 101895093
SCAC: 106096271
LCQ: 111679071
LSQ: 119609107
GFS: 119641950 119641959
ECOE: 129938412 129944518
CLON: 129609511
HIS: 119652245
AGA: 1272172 1272625
ACOZ: 120957733 120958964
AARA: 120904516 120906754
AMER: 121597780 121600548 121601281
ASTE: 118507373 118510114
AFUN: 125764686 125772347
AMOU: 128297041 128307217
AALI: 118462907
AAG: 5572256
AALB: 109422192
ASUA: 134207693
CQU: CpipJ_CPIJ016469 CpipJ_CPIJ016470 CpipJ_CPIJ016471
CPII: 120432262 120432275
CNS: 116337381 116338998 116339000 116340392 116345742 116345987 116346151 116351855 116351914 116351916
BCOO: 119069337 119084775
AME: 413742
ACER: 108001157
ALAB: 122712845
ADR: 102673881
AFLR: 100864112
BIM: 100743540
BBIF: 117209933
BVK: 117230840
BVAN: 117166453
BTER: 100647789
BAFF: 126924528
BPYO: 122576024
BPAS: 132911729
FVI: 122536235
CCAL: 108630675
OBB: 114873069
OLG: 117610430
MGEN: 117219619
NMEA: 116431444
CGIG: 122394871
SOC: 105193817
MPHA: 105832515
AEC: 105148183
ACEP: 105624336
PBAR: 105433521
VEM: 105563878
HST: 105184844
DQU: 106749703
CFO: 105254529
FEX: 115240525
LHU: 105672556(Stat92E)
PGC: 109854643
OBO: 105281780
PCF: 106789625
PFUC: 122513482
VPS: 122636943
VCRB: 124430937
VVE: 124957094
NVI: 100121885
CSOL: 105361759
TPRE: 106651566
LHT: 122509003
LBD: 127288127
MDL: 103580774
CGLO: 123263507
FAS: 105266810
DAM: 107040670
AGIF: 122848525
CINS: 118067250
VCAN: 122419562
CCIN: 107275017
DSM: 124413078
NPT: 124221560
NFB: 124184852
NLO: 107227203
NVG: 124307088
AROA: 105693409
TCA: 657965(Stat)
DPA: 109540291
SOY: 115875164
AGRG: 126746020
ATD: 109594135
CSET: 123312582
AGB: 108914584
LDC: 111509439
DVV: 114330294 114330295
NVL: 108559383
APLN: 108732879
PPYR: 116170388
OTU: 111415033
BMOR: 100302627(Stat)
BMAN: 114244414
MSEX: 115451759
DPL: KGM_212956A KGM_212956B
BANY: 112051221
MJU: 123879668
NIQ: 126779907
MCIX: 123666162 123666245 123666273
PPOT: 106107473
PXU: 106126003
PRAP: 110992522
PBX: 123715650
PNAP: 125061300
ZCE: 119838494
CCRC: 123704742
LSIN: 126975029
AAGE: 121736540
HAW: 110381656
HZE: 124644398
TNL: 113509063
SLIU: 111359030
OFU: 114354585
ATRA: 106132869
GMW: 113513772
PXY: 105396563
PGW: 126379405
LGLY: 125239563
CFEL: 113369752
CCRN: 123290948
API: 100161101
DNX: 107161813 107165640
AGS: 114122874 114124139
RMD: 113551947 113554657
ACOO: 126833934 126833935
DVT: 126908329
BTAB: 109041216
DCI: 103509325
CLEC: 106661659 106661660
HHAL: 106683428(Stat92E)
NLU: 111049728
HVI: 124353062
MQU: 128992970
PHU: Phum_PHUM335200
FOC: 113201738
TPAL: 117640738 117641607 117652812
ZNE: 110830516
CSEC: 111869855
SGRE: 126267038
BROR: 134535922
IEL: 124163999
FCD: 110847260 110849442 110852141 110852198 110855838 110856878
DPX: DAPPUDRAFT_97641
DMK: 116924054 123471049
DPZ: 124320263
PVM: 113830023
PJA: 122265890
PCHN: 125040688
PMOO: 119587821 119587822
HAME: 121867031 121878028
PCLA: 123758708
CQD: 128701161
PTRU: 123508992
ESN: 126983902
MNZ: 135219184
HAZT: 108670131 108674474
EAF: 111703470 111703983
LSM: 121119572 121124574
TCF: 131886801 131889088
PPOI: 119111901
ISC: 8053058
DSV: 119456101
RSAN: 119378366 119393749
RMP: 119171954
VDE: 111250469 111254110
VJA: 111259316 111260757
TUT: 107366189 107369996
DPTE: 113793271 113799653
DFR: 124491828 124495363
CSCU: 111623415
CVS: 136968410(Stat92E)
ABRU: 129989007
UDV: 129226409
SDM: 118189820
LPOL: 106463512
PMEO: 129588506
CEL: CELE_Y51H4A.17(sta-1)
CBR: CBG_13675(Cbr-sta-1)
CRQ: GCK72_012475 GCK72_012477
NAI: NECAME_09201
BMY: BM_BM6729(Bma-sta-1)
LOA: LOAG_04974
TSP: Tsp_04456
PCAN: 112554412 112574768
BGT: 106065668 106065669
GAE: 121370464
HRF: 124139325 125372347
HRJ: 124262653 124269736
CRG: 105318228 105335326
CANU: 128180799
CVN: 111123278 111128718
OED: 125647476 130047050
MYI: 110453520 110460766 110463563 110463564
PMAX: 117321668 117321839 117322263
MCAF: 127728683
MMER: 123560704 123561466
RPHI: 132729437 132758783
DPOL: 127859291
MAEA: 128233517
OSN: 115220884
LJP: 135462026
LAK: 106175814 106177519
LLON: 135497611 135501300
EPA: 110233275 110234065
ATEN: 116286281 116286282
ADF: 107338381
AMIL: 114964117
SPIS: 111328363
XEN: 124437962
HMG: 100206878
HSY: 130621485 130621486
RES: 135682336
TAD: TRIADDRAFT_52438
AQU: 100641588
MBR: MONBRDRAFT_44371
SRE: PTSG_04084
 » show all
Reference
PMID:8732682
  Authors
Silva CM, Lu H, Day RN
  Title
Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
  Journal
Mol Endocrinol 10:508-18 (1996)
DOI:10.1210/mend.10.5.8732682
  Sequence
[hsa:6777]

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