KEGG ORTHOLOGY: K11221

ORTHOLOGY: K11221

Entry

K11221                      KO

Symbol

STAT2

Name

signal transducer and activator of transcription 2

Pathway

map04062

Chemokine signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04620

Toll-like receptor signaling pathway

map04621

NOD-like receptor signaling pathway

map04625

C-type lectin receptor signaling pathway

map04630

JAK-STAT signaling pathway

map05160

Hepatitis C

map05161

Hepatitis B

map05162

Measles

map05164

Influenza A

map05165

Human papillomavirus infection

map05167

Kaposi sarcoma-associated herpesvirus infection

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05171

Coronavirus disease - COVID-19

map05200

Pathways in cancer

Disease

H00840

Pseudo-TORCH syndrome

H02525

Disorders of innate immunity

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K11221  STAT2; signal transducer and activator of transcription 2
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04621 NOD-like receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04625 C-type lectin receptor signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
   04062 Chemokine signaling pathway
    K11221  STAT2; signal transducer and activator of transcription 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K11221  STAT2; signal transducer and activator of transcription 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K11221  STAT2; signal transducer and activator of transcription 2
  09172 Infectious disease: viral
   05161 Hepatitis B
    K11221  STAT2; signal transducer and activator of transcription 2
   05160 Hepatitis C
    K11221  STAT2; signal transducer and activator of transcription 2
   05171 Coronavirus disease - COVID-19
    K11221  STAT2; signal transducer and activator of transcription 2
   05164 Influenza A
    K11221  STAT2; signal transducer and activator of transcription 2
   05162 Measles
    K11221  STAT2; signal transducer and activator of transcription 2
   05168 Herpes simplex virus 1 infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05167 Kaposi sarcoma-associated herpesvirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05169 Epstein-Barr virus infection
    K11221  STAT2; signal transducer and activator of transcription 2
   05165 Human papillomavirus infection
    K11221  STAT2; signal transducer and activator of transcription 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K11221  STAT2; signal transducer and activator of transcription 2
Transcription factors [BR:ko03000]
Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11221  STAT2; signal transducer and activator of transcription 2

Genes

HSA:	6773(STAT2)

PTR:	451996(STAT2)

PPS:	100972085(STAT2)

GGO:	101146695(STAT2)

PON:	100452011(STAT2)

PPYG:

129010795(STAT2)

NLE:	100585171(STAT2)

HMH:	116480910(STAT2)

SSYN:

129465186(STAT2)

MCC:	712694(STAT2)

MCF:	102133020(STAT2)

MTHB:

126931203

MNI:	105474140(STAT2)

CSAB:

103238525(STAT2)

CATY:

105587295(STAT2)

PANU:

101011342(STAT2)

TGE:	112634334(STAT2)

MLEU:

105529948(STAT2)

RRO:	104673676(STAT2)

RBB:	108516059(STAT2)

TFN:	117089929(STAT2)

PTEH:

111541846(STAT2)

CANG:

105500610(STAT2)

CJC:	100393190(STAT2)

SBQ:	101029836(STAT2)

CIMI:

108309779(STAT2)

ANAN:

105715955(STAT2)

CSYR:

103258295

MMUR:

105865362(STAT2)

LCAT:

123639648(STAT2)

PCOQ:

105817095(STAT2)

OGA:	100944401(STAT2)

MMU:	20847(Stat2)

MCAL:

110302854(Stat2)

MPAH:

110326622(Stat2)

RNO:	288774(Stat2)

MCOC:

116076236(Stat2)

ANU:	117696619(Stat2)

MUN:	110559388(Stat2)

CGE:	100764772(Stat2)

MAUA:

101830537(Stat2)

PROB:

127215637(Stat2)

PLEU:

114681747(Stat2)

MORG:

121462696(Stat2)

MFOT:

126491990

AAMP:

119803231(Stat2)

NGI:	103746519(Stat2)

HGL:	101707295(Stat2)

CPOC:

100719719(Stat2)

CCAN:

109686120(Stat2)

DORD:

105990116(Stat2)

DSP:	122124118(Stat2)

PLOP:

125362786(Stat2)

NCAR:

124983364

MMMA:

107140168(Stat2)

OCU:	100344467 127491150

OPI:	101536685(STAT2)

TUP:	102477989(STAT2)

GVR:	103594016(STAT2)

CFA:	481111(STAT2)

CLUD:

112678012(STAT2)

VVP:	112922378(STAT2)

VLG:	121491356(STAT2)

NPO:	129511791(STAT2)

AML:	100472167(STAT2)

UMR:	103656206(STAT2)

UAH:	113256419(STAT2)

UAR:	123787247(STAT2)

ELK:

111160141

LLV:

125106747

MPUF:

101690720(STAT2)

MNP:	132019801(STAT2)

MLK:	131838598(STAT2)

NVS:	122891158(STAT2)

ORO:	101368050(STAT2)

EJU:	114214932(STAT2)

ZCA:	113922098(STAT2)

MLX:	118008707(STAT2)

NSU:	110577818(STAT2)

LWW:	102739614(STAT2)

FCA:	101099224(STAT2)

PYU:	121040920(STAT2)

PCOO:

112863559(STAT2)

PBG:	122473765(STAT2)

PVIV:

125170213(STAT2)

LRUF:

124501367

PTG:	102967399(STAT2)

PPAD:

109270329(STAT2)

PUC:

125920249

AJU:

106986878

HHV:	120219936(STAT2)

BTA:	511023(STAT2)

BOM:	102277710(STAT2)

BIU:	109559357(STAT2)

BBUB:

102414314(STAT2)

BBIS:

104988072(STAT2)

CHX:	102190301(STAT2)

OAS:	101108211(STAT2)

BTAX:

128047300(STAT2)

ODA:	120857446(STAT2)

CCAD:

122427313(STAT2)

MBEZ:

129537127(STAT2)

SSC:	396923(STAT2)

CFR:	102510903(STAT2)

CBAI:

105075886(STAT2)

CDK:	105086362(STAT2)

VPC:	102545696(STAT2)

BACU:

103000458(STAT2)

BMUS:

118901552(STAT2)

LVE:	103081732(STAT2)

OOR:	101281591(STAT2)

DLE:	111173869(STAT2)

PCAD:

102981574(STAT2)

PSIU:

116760219(STAT2)

NASI:

112394097(STAT2)

ECB:	100052513(STAT2)

EPZ:	103557548(STAT2)

EAI:	106832955(STAT2)

MYB:	102240965(STAT2)

MYD:	102766233(STAT2)

MMYO:

118651142(STAT2)

MLF:	102430852(STAT2)

MDT:	132227766(STAT2)

PKL:	118729130(STAT2)

EFUS:

103292429(STAT2)

MNA:	107546189(STAT2)

DRO:	112319116(STAT2)

SHON:

118975851(STAT2)

AJM:	119040310(STAT2)

PDIC:

114513273(STAT2)

PHAS:

123812791(STAT2)

MMF:	118623876(STAT2)

PPAM:

129075775(STAT2)

HAI:	109396910(STAT2)

RFQ:	117028885(STAT2)

PALE:

102879640(STAT2)

PGIG:

120604905(STAT2)

PVP:	105302576(STAT2)

RAY:	107521231(STAT2)

MJV:	108402236(STAT2)

TOD:	119248061(STAT2)

SARA:

101550386(STAT2)

SETR:

126022154(STAT2)

LAV:	100656374(STAT2)

TMU:

101348948

ETF:	101661602(STAT2)

DNM:	101423495(STAT2)

GAS:	123250724(STAT2)

SHR:	100933167(STAT2)

AFZ:

127564177

PCW:	110210934(STAT2)

TVP:	118849960(STAT2)

OAA:	100087549(STAT2)

GGA:	100858732(STAT2)

PCOC:

116239827(STAT2)

MGP:	104916177(STAT2)

CJO:	107325845(STAT2)

TPAI:

128071944(STAT2)

LMUT:

125685612(STAT2)

NMEL:

110389141(STAT2)

APLA:

119714613(STAT2)

ACYG:

125181336(STAT2)

CATA:

118260153(STAT2)

AFUL:

116499942(STAT2)

TGU:

105760310

LSR:	110477089(STAT2)

PMOA:

120507567 120513580

OTC:	121337502(STAT2)

PRUF:

121358943(STAT2)

FAB:

101821433

OMA:	130265681(STAT2)

PHI:	102112270(STAT2)

ETL:	114070775(STAT2)

ZLE:	135459115(STAT2)

SVG:	106863158(STAT2)

HRT:	120764444(STAT2)

SATI:

136372778(STAT2)

FPG:	101912561(STAT2)

FCH:	106630923(STAT2)

SHAB:

115618700(STAT2)

TALA:

116963079(STAT2)

ACHC:

115351351(STAT2)

HLE:	104830351(STAT2)

AGEN:

126046516

AFOR:

103899559

RTD:	128903206(STAT2)

AROW:

112974309(STAT2)

NPD:	112955622(STAT2)

DNE:	112996983(STAT2)

ASN:	106721797(STAT2)

AMJ:	102574603(STAT2)

CPOO:

109322912(STAT2)

GGN:	109295410(STAT2)

CMY:	102932386(STAT2)

CCAY:

125627841(STAT2)

DCC:	119845671(STAT2)

CPIC:

101944167(STAT2)

CABI:

116827740(STAT2)

MRV:	120391254(STAT2)

ACS:	103277767(stat2)

ASAO:

132768316(STAT2)

PVT:	110074594(STAT2)

SUND:

121921484(STAT2)

PBI:	103065958(STAT2)

PMUR:

107290900(STAT2)

CTIG:

120305466(STAT2)

TSR:	106544441(STAT2)

PGUT:

117662768(STAT2)

APRI:

131191430(STAT2)

PTEX:

113447314(STAT2)

NSS:	113420192(STAT2)

VKO:	123019034(STAT2)

PMUA:

114586539(STAT2)

PRAF:

128406900(STAT2)

ZVI:	118079505(STAT2)

HCG:	128345788(STAT2)

GJA:	107126172(STAT2)

STOW:

125430031(STAT2)

EMC:	129328133(STAT2)

XLA:	108708573(stat2.L) 108709841(stat2.S)

XTR:	100170174(stat2)

NPR:

108791510

RTEM:

120929512(STAT2)

BBUF:

120996012(STAT2)

BGAR:

122930988(STAT2)

MUO:	115465885(STAT2)

GSH:	117358070(STAT2)

DRE:	565200(stat2)

SRX:	107711071 107733592

SANH:

107667368 107673542

SGH:	107582712 107585138

CCAR:

109081275

CAUA:

113050351 113094065

CGIB:

127960183 128015726

PTET:

122347498(stat2)

LROH:

127166603(stat2)

OMC:	131542395(stat2)

PPRM:

120491376(stat2)

RKG:	130087560(stat2)

MAMB:

125273698(stat2)

CIDE:

127513816

CERY:

137011712(stat2)

MASI:

127445754 127448824

TROS:

130556375(stat2)

TDW:	130424265(stat2)

MANU:

129450296(stat2)

IPU:	108272207(stat2)

IFU:	128614774(stat2)

PHYP:

113545874

SMEO:

124399142(stat2)

TFD:	113660522(stat2)

TVC:	132844152(stat2)

TRN:	134317205(stat2)

AMEX:

103021407(stat2)

CMAO:

118808245(stat2)

EEE:

113567990

CHAR:

105897943(stat2)

TRU:

101071462

TFS:	130524302(stat2)

LCO:

104931961

NCC:

104966838

TBEN:

117489454(stat2)

CGOB:

115007853

PGEO:

117446139(stat2)

GACU:

117551086(stat2)

EMAC:

134883587(stat2)

ELY:	117257067(stat2)

EFO:	125892992(stat2)

PLEP:

121955727(stat2)

SLUC:

116065448(stat2)

ECRA:

117943306(stat2)

ESP:

116688367

PFLV:

114553646

GAT:	120835023(stat2)

PPUG:

119229650(stat2)

AFB:	129106335(stat2)

CLUM:

117730251(stat2)

PSWI:

130207963(stat2)

MSAM:

119886144(stat2)

SCHU:

122867140(stat2)

CUD:	121506826(stat2)

ALAT:

119020489(stat2)

MZE:

101479682

ONL:

100701534

OAU:	116336550(stat2)

OLA:

101173855

OML:	112144620(stat2)

CSAI:

133448749(stat2)

XMA:

XCO:

XHE:

PRET:

PFOR:

103147660(stat2) 103147661

PLAI:

106954437

PMEI:

106909628 106924395

GAF:	122834731(stat2)

PPRL:

129357678(stat2)

CVG:

107082130

CTUL:

119776668(stat2)

GMU:	124856810(stat2)

NFU:

107385678

KMR:	108235753(stat2)

ALIM:

106518034(stat2)

NWH:	119411927(stat2)

AOCE:

111566617

MCEP:

125006679(stat2)

CSEM:

103385958

POV:

109629253

SSEN:

122768157(stat2)

HHIP:

117761297(stat2)

HSP:	118105504(stat2)

PPLT:

128447619(stat2)

SMAU:

118309014(stat2)

LCF:	108881447(stat2)

SDU:

111221460

SLAL:

111667811

XGL:	120807379(stat2)

HCQ:

109522346

SSCV:

125977770

SBIA:

133507561(stat2)

PEE:	133409336(stat2)

PTAO:

133483313(stat2)

BPEC:

110168365

MALB:

109956049

BSPL:

114855222(stat2)

SJO:	128355051(stat2)

SASA:

100270812(stat2)

STRU:

115207827

OTW:	112217577(stat2)

OMY:	110494323(stat2)

OGO:	124002667(stat2)

ONE:

115143174

OKI:

109895769

OKE:	118388565(stat2)

SALP:

111966796

SNH:	120061182(stat2)

CCLU:

121575263(stat2)

ELS:

105017162

SFM:

108918442

PKI:

111854344

AANG:

118210889(stat2)

LOC:

102698942

PSPA:

121309023(stat2)

ARUT:

117401040 117966965

PSEX:

120524824(stat2)

LCM:	102355078(STAT2)

CMK:

103191066

» show all

Reference

PMID:1502204

Authors

Fu XY, Schindler C, Improta T, Aebersold R, Darnell JE Jr

Title

The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.

Journal

Proc Natl Acad Sci U S A 89:7840-3 (1992)
DOI:10.1073/pnas.89.16.7840

Sequence

[hsa:6773]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (34)   
   KEGG PATHWAY (34)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (415)   
   KEGG GENES (359)   
   KEGG MGENES (42)   
   RefGene (12)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (454)   

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