KEGG ORTHOLOGY: K11822

ORTHOLOGY: K11822

Entry

K11822                      KO

Symbol

SULT2A

Name

bile-salt sulfotransferase [EC:2.8.2.14]

Pathway

map00980

Metabolism of xenobiotics by cytochrome P450

map04976

Bile secretion

map05204

Chemical carcinogenesis - DNA adducts

Reaction

R09444

3'-phosphoadenylyl-sulfate:7-hydroxymethyl-12-methylbenz[a]anthracene sulfotransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K11822  SULT2A; bile-salt sulfotransferase
09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K11822  SULT2A; bile-salt sulfotransferase
09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    K11822  SULT2A; bile-salt sulfotransferase
Enzymes [BR:ko01000]
2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.2  Sulfotransferases
    2.8.2.14  bile-salt sulfotransferase
     K11822  SULT2A; bile-salt sulfotransferase

Other DBs

GO:

0047704

Genes

HSA:	6822(SULT2A1)

PTR:	456409(SULT2A1)

PPS:	100971784(SULT2A1)

GGO:	101137965(SULT2A1)

PON:	100431471(SULT2A1)

PPYG:

129020856(SULT2A1)

NLE:	100603984(SULT2A1)

HMH:	116479417(SULT2A1)

SSYN:

129460259(SULT2A1)

MCC:	717600(SULT2A1)

MCF:	102130325(SULT2A1)

MTHB:

126943497

MNI:	105478620(SULT2A1)

CSAB:

103234953(SULT2A1)

CATY:

105595217(SULT2A1)

PANU:

101000955(SULT2A1)

TGE:	112611897(SULT2A1)

MLEU:

105531904(SULT2A1)

RRO:	104673376(SULT2A1)

RBB:	108539899(SULT2A1)

TFN:	117091485(SULT2A1)

PTEH:

111520101(SULT2A1)

CANG:

105500701(SULT2A1)

CJC:	100413663(SULT2A1)

SBQ:	101034912 101040745

CIMI:

108283861(SULT2A1) 108316657

ANAN:

105713139 105713148(SULT2A1) 105726038

CSYR:

103256265(SULT2A1) 103268128 103272673

MMUR:

105868193 105868194 105869600(SULT2A1) 105873827

LCAT:

123623885(SULT2A1)

PCOQ:

105817707(SULT2A1)

OGA:	100942680 100949505 100954287 100954595 100954909 100956260 100956575 100956888 100957203 100957822 100958792

MMU:	20859(Sult2a1) 434121(Sult2a4) 434264(Sult2a5) 629203(Sult2a3) 629219(Sult2a6) 638251(Sult2a7) 76971(Sult2a8)

MCAL:

110287694 110297377 110298916 110299139(Sult2a1)

MPAH:

110315086(Sult2a1) 110315385

RNO:	120099768 134485278 24912(Sult2a1) 361510(Sult2a2)

MCOC:

116100275 116100375 116100378

ANU:	117698023 117700514 117700537 117700538 117700547

ASYL:

127674798 127674804 127674815 127683358 127683370 127683380 127683393

MUN:	110539543(Sult2a1)

CGE:	100751331 100751624 100751913 100752375 100752864 100753164 103160274 103160275 113837373

MAUA:

101826585 101831195 101841850 121132754

PROB:

127238495 127238564 127238873 127238874

MORG:

121449068 121449462 121449475 121449499 121449521 121449541

MFOT:

126494651 126494652 126494653 126494654 126494655 126496033

AAMP:

119820497 119820498 119820499 119820952

NGI:	103729182 103732419 103732424

HGL:	101704327(Sult2a1) 101704668 101705514

CPOC:

100379531(Std2) 100379581(Std1) 100721490 100729579 100730125 100731507

CCAN:

109675537

DORD:

106000940 106000941 106000942 106000944 106000945 106000946 106000948

PLOP:

125368085 125368428 125368429 125368431 125368432 125368433 125368434 125368435 125368436 125368437 125368442 125368443 125368444

NCAR:

124974873 124974875 124974876 124974882 124974883 124974884 124974887

MMMA:

107151302 107151305 107151307 107151308 107151585 107151666

ITI:	101961002 101961474 101962223 101962512 101962791 101963557 101964048 101964325 101964782 101965284 101965764 101966648 101967896 101968370 110599253 110599257 120888064

OCU:	100008598(SULT2A1)

OPI:	101532090(SULT2A1)

TUP:	102469211 102470067

GVR:	103607526(SULT2A1)

BTA:	514658 533560(SULT2A1)

BOM:	102268811 102269085 138991669

BIU:	109572833 109572834

BBUB:

102395145 102395467

BBIS:

104995597 104995599 104995707

CHX:	102181069 108633179

OAS:	101119842 101120103

BTAX:

128063820 128063825

CSUM:

138095841 138095942

ODA:	120872213 120872214

CCAD:

122420940 122421647 122421698

MREE:

136158849 136161501

OVR:	110125743(SULT2A1) 110150756

MBEZ:

129546189 129546190

SSC:	641359(SULT2A1)

CFR:	102518264(SULT2A1)

CBAI:

105062573(SULT2A1)

CDK:	105098927(SULT2A1)

VPC:	102528443(SULT2A1)

BACU:

103005028(SULT2A1)

BMUS:

118884579 118885428(SULT2A1)

OOR:

LALB:

GMF:

DDP:

DLE:

PSIU:

NASI:

ECB:	100050266 100050329 100050400 100050477(SULT2A1) 100050557 100052843 100052993

EPZ:	103555784 103567536

EAI:	106828268 106829389 106838230 106838231 106845150 123281273

MYB:	102240460 102254636(SULT2A1)

MYD:	102762349 102762941(SULT2A1)

MMYO:

118655128 118655129 118657508(SULT2A1)

MLF:	102421645 102431147 102437703

MDT:	132216046 132216047 132216656(SULT2A1)

MYUM:

138999569 138999570 138999756(SULT2A1)

PKL:	118715986(SULT2A1) 118716937

EFUS:

103297671(SULT2A1) 103303896 129147041

MNA:	107540047(SULT2A1)

DRO:	112312826(SULT2A1) 112313480

AJM:	119065861 128627865 128627903(SULT2A1)

PDIC:

114511474(SULT2A1)

PHAS:

123813613 123822928(SULT2A1)

PPAM:

129082573 129082891(SULT2A1)

HAI:	109390976(SULT2A1)

RFQ:	117034323(SULT2A1) 117034619

PALE:

102890032(SULT2A1)

PGIG:

120605973 120606999

PVP:	105304188(SULT2A1)

RAY:	107516041(SULT2A1)

SARA:

101551700 101551967 101552228 101552765 101553298 101553558 101553824 101554810 101555003 101555270 101555797

SFUM:

130043324 130044153 130044155 130044212 130044237 130044266 130044349

SETR:

126027521 126027526(SULT2A1) 126027529

LAV:	100654856 100655145 100655424 104845577

TMU:	101344801 101351802

ETF:	105979774 105979776

DNM:	101414352 101416234 101417110 101429367 101431737 101440175 101441775 101443992 101444147

MDO:	100018596 100018631

GAS:	123239008(SULT2A1)

SHR:	100920297 105750186

AFZ:	127556915 127557689 127557692

PCW:	110220147 110220161

TVP:	118835311 118835316 118838698(SULT2A1)

PBRV:

138173314(SULT2A1)

AJJ:	139972848 139972864 139979164

PFLL:

139145312 139145323 139145329

RSAN:

RMP:

VDE:

VJA:

CRG:	105318023 105340600 136269644 136269713 136270929 136270948 136270985 136271050

CANU:

128179979 128181726

OED:

125667857

PMAX:

117317893

WIJ:	BWZ20_04230

ALTI:

ALE3EI_0126

» show all

Reference

PMID:20102295

Authors

Huang J, Bathena SP, Tong J, Roth M, Hagenbuch B, Alnouti Y

Title

Kinetic analysis of bile acid sulfation by stably expressed human sulfotransferase 2A1 (SULT2A1).

Journal

Xenobiotica 40:184-94 (2010)
DOI:10.3109/00498250903514607

Sequence

[hsa:6822]

Reference

PMID:11535246

Authors

Glatt H, Boeing H, Engelke CE, Ma L, Kuhlow A, Pabel U, Pomplun D, Teubner W, Meinl W

Title

Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects.

Journal

Mutat Res 482:27-40 (2001)
DOI:10.1016/S0027-5107(01)00207-X

All links

Ontology (1)   
   GO (1)   
Gene (23)   
   MGENES (9)   
   RefGene (11)   
   OC (3)   
All databases (24)   

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