KEGG ORTHOLOGY: K11828

ORTHOLOGY: K11828

Entry

K11828                      KO

Symbol

DLG4, PSD95

Name

discs large protein 4

Pathway

map04390

Hippo signaling pathway

map04724

Glutamatergic synapse

map05016

Huntington disease

map05022

Pathways of neurodegeneration - multiple diseases

map05030

Cocaine addiction

Disease

H00773

Autosomal dominant intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K11828  DLG4, PSD95; discs large protein 4
09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    K11828  DLG4, PSD95; discs large protein 4
09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    K11828  DLG4, PSD95; discs large protein 4
   05022 Pathways of neurodegeneration - multiple diseases
    K11828  DLG4, PSD95; discs large protein 4
  09165 Substance dependence
   05030 Cocaine addiction
    K11828  DLG4, PSD95; discs large protein 4
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K11828  DLG4, PSD95; discs large protein 4
Membrane trafficking [BR:ko04131]
SNARE
  SNARE associated proteins
   Others
    K11828  DLG4, PSD95; discs large protein 4
Endocytosis
  Clathrin-mediated endocytosis
   LDLR adaptor proteins
    K11828  DLG4, PSD95; discs large protein 4

Genes

HSA:	1742(DLG4)

PTR:	468444(DLG4)

PPS:	100985837(DLG4)

GGO:	101145671(DLG4)

PON:	100453630(DLG4)

PPYG:

129017470(DLG4)

NLE:	100585245(DLG4)

HMH:	116459315(DLG4)

SSYN:

129470621(DLG4)

MCC:	714273(DLG4)

MCF:	101865770(DLG4)

MTHB:

126939676

MNI:	105473169(DLG4)

CSAB:

103242276(DLG4)

CATY:

105582698(DLG4)

PANU:

101018290(DLG4)

TGE:	112608976(DLG4)

MLEU:

105549905(DLG4)

RRO:	104673336(DLG4)

RBB:	108514296(DLG4)

TFN:	117067799(DLG4)

PTEH:

111535237(DLG4)

CANG:

105523589(DLG4)

CJC:	100398576(DLG4)

SBQ:	101027754(DLG4)

CIMI:

108306600(DLG4)

ANAN:

105720769(DLG4)

CSYR:

103263237(DLG4)

MMUR:

105877910(DLG4)

LCAT:

123650851(DLG4)

PCOQ:

105819386(DLG4) 105822860

OGA:	100946622(DLG4)

MMU:	13385(Dlg4)

MCAL:

110304162(Dlg4)

MPAH:

110332219(Dlg4)

RNO:	29495(Dlg4)

MCOC:

116079061(Dlg4)

ANU:	117711750(Dlg4)

MUN:	110555094(Dlg4)

CGE:	100762874(Dlg4)

MAUA:

101825384(Dlg4)

PROB:

127219009(Dlg4)

PLEU:

114693208(Dlg4)

MORG:

121456539(Dlg4)

MFOT:

126513894

AAMP:

119811175(Dlg4)

NGI:	103752160(Dlg4)

HGL:	101708587(Dlg4)

CPOC:

100717910(Dlg4)

CCAN:

109674497(Dlg4)

DORD:

105983292(Dlg4)

DSP:	122100419(Dlg4)

PLOP:

125365203(Dlg4)

NCAR:

124981029

MMMA:

107157969(Dlg4)

OCU:

100339587

OPI:	101517434(DLG4)

TUP:	102486732(DLG4)

GVR:	103591442(DLG4)

CFA:	489462(DLG4)

CLUD:

112647484(DLG4)

VVP:	112924816(DLG4)

VLG:	121499760(DLG4)

NPO:	129496980(DLG4)

AML:	100479751(DLG4)

UMR:	103660461(DLG4)

UAR:	123792170(DLG4)

ELK:

111161072

LLV:

125087807

MPUF:

101677223(DLG4)

MNP:	132003336(DLG4)

MLK:	131815750(DLG4)

NVS:	122906683(DLG4)

ORO:	101375926(DLG4)

EJU:	114225360(DLG4)

ZCA:	113939371(DLG4)

MLX:	117999988(DLG4)

NSU:	110584451(DLG4)

LWW:	102737201(DLG4)

FCA:	101093902(DLG4)

PYU:	121016027(DLG4)

PCOO:

112856981(DLG4)

PBG:	122484849(DLG4)

PVIV:

125151463(DLG4)

LRUF:

124519480

PTG:	102968603(DLG4)

PPAD:

109245977(DLG4)

PUC:

125927065

AJU:

106972413

HHV:	120231439(DLG4)

BTA:	100137840(DLG4)

BOM:	102282219(DLG4)

BIU:	109573932(DLG4)

BBUB:

102406488(DLG4)

BBIS:

104993932(DLG4)

CHX:	102187803(DLG4)

OAS:	101116743(DLG4)

BTAX:

128064844(DLG4)

ODA:	120866078(DLG4)

CCAD:

122446171(DLG4)

MBEZ:

129542591(DLG4)

SSC:	100626077(DLG4)

CFR:	102504814(DLG4)

CBAI:

105077478(DLG4)

CDK:	105103049(DLG4)

VPC:	102538659(DLG4)

BACU:

103001428(DLG4)

BMUS:

118886460(DLG4)

LVE:	103077734(DLG4)

OOR:	101275062(DLG4)

DLE:	111185662(DLG4)

PCAD:

102974250(DLG4)

PSIU:

116745053(DLG4)

NASI:

112390406(DLG4)

ECB:	100061544(DLG4)

EPZ:	103540298(DLG4)

EAI:	106844173(DLG4)

MYB:	102257650(DLG4)

MYD:	102773344(DLG4)

MMYO:

118672039(DLG4)

MLF:	102425018(DLG4)

MDT:	132218093(DLG4)

PKL:

118726929

EFUS:

103296933(DLG4)

MNA:	107544252(DLG4)

DRO:	112308630(DLG4)

SHON:

118974682(DLG4)

AJM:	119037134(DLG4)

PDIC:

114514990(DLG4)

PHAS:

123809239(DLG4)

MMF:	118633801(DLG4)

PPAM:

129072307(DLG4)

HAI:	109394613(DLG4)

RFQ:	117012845(DLG4)

PALE:

102889275(DLG4)

PGIG:

120589628(DLG4)

PVP:	105291735(DLG4)

RAY:	107509512(DLG4)

MJV:	108401218(DLG4)

TOD:	119232658(DLG4)

SARA:

101544407(DLG4)

SETR:

125998007(DLG4)

LAV:	100656811(DLG4)

TMU:

101360753

ETF:	101645449(DLG4)

DNM:	101414812(DLG4)

MDO:	100016655(DLG4)

GAS:	123244463(DLG4)

SHR:	100930883(DLG4)

AFZ:

127560913

PCW:	110194304(DLG4)

TVP:	118856747(DLG4)

OAA:	100078807(DLG4)

ACYG:

125181793(DLG4)

LSR:

110481216

GFR:

102036398

ZLE:	135461206(DLG4)

HLE:	104836979(DLG4)

AGEN:

126034669

NNI:

104012563

CUCA:

128849963(DLG4)

AROW:

112963324

ASN:	102377313(DLG4)

AMJ:	102560362(DLG4)

PSS:	102443619(DLG4)

CCAY:

125628607(DLG4)

DCC:	119849227(DLG4)

CPIC:

101944806

CABI:

116828316

MRV:	120381794(DLG4)

ACS:

103281952

ASAO:

132777545(DLG4)

PVT:	110082313(DLG4)

SUND:

121934911(DLG4)

PBI:	103066401(DLG4)

PMUR:

107300335(DLG4)

CTIG:

120305691(DLG4)

TSR:

106552297

PGUT:

117656537(DLG4)

APRI:

131196871(DLG4)

VKO:	123016649(DLG4)

PMUA:

114608043(DLG4)

PRAF:

128400151(DLG4)

ZVI:	118094274(DLG4)

HCG:	128329795(DLG4)

GJA:	107118070(DLG4)

STOW:

125443941(DLG4)

EMC:	129340378(DLG4)

XLA:	108703559 108711809

XTR:	779559(dlg4)

RTEM:

120921683(DLG4)

BBUF:

120986722(DLG4)

BGAR:

122923393(DLG4)

MUO:	115457672(DLG4)

GSH:	117350747(DLG4)

DRE:	100000823(dlg4) 405796(dlg4b)

SRX:	107719528 107722747 107740023 107750158 107752257

SANH:

107662062 107675644 107679371 107702891

SGH:	107556052 107560322 107573201 107575728

CCAR:

109079797

CAUA:

113041376 113085558 113094274

CGIB:

127944625 127957919 127990697 128012166

PTET:

122325079 122334594(dlg4b) 122335060

LROH:

127162258(dlg4b) 127165109

OMC:	131531991(dlg4b) 131540853

PPRM:

120463434(dlg4b) 120472287

RKG:

130082541

MAMB:

125259870(dlg4b) 125267810

CIDE:

127504516 127513280

CERY:

137008690(dlg4b) 137033933

MASI:

127419553 127419822 127426041 127437210

TROS:

130545579(dlg4b) 130564177

TDW:	130408956(dlg4b) 130419149

MANU:

129431537(dlg4b) 129441069

IPU:	108261710 108275614(dlg4b)

IFU:

128619293

PHYP:

113531412

SMEO:

124378835 124398615(dlg4b)

TVC:	132841122 132862770

TRN:	134302994 134333393(dlg4b)

AMEX:

103040987(dlg4b) 103046947

CMAO:

118814895 118822489

EEE:

113586849

CHAR:

105904570 105906628

TRU:	101070789 101079306

TFS:	130523050 130537825

TNG:	GSTEN00019059G001

LCO:	104936939 104938060

NCC:	104941840(dlg4)

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117246073(dlg4b) 117266935

EFO:	125884129(dlg4b) 125898410

PLEP:

121952440

SLUC:

116061910(dlg4b) 116064863

ECRA:

117955055

ESP:	116700328(dlg4)

PFLV:

114546100 114566423

GAT:	120821413 120821910

PPUG:

119215918 119221827(dlg4b)

AFB:	129093683 129113872

CLUM:

117742418 117747614(dlg4b)

PSWI:

130191726 130212042

MSAM:

119895724 119912410

SCHU:

122870112(dlg4b) 122888501

CUD:	121504687(dlg4b) 121519025

ALAT:

119027802 119031315

MZE:	101463677 101466812 112431553

ONL:	100690710 100693164 100702423

OAU:	116319865 116336192 120438596

OLA:

101159214

OML:

112142280

CSAI:

133420307 133459580

XMA:	102228667 102232201

XCO:	114140581 114153207

XHE:	116728646(dlg4) 116732812

PRET:

103475845(dlg4)

PFOR:

103129600 103141707(dlg4)

PLAI:

106935253(dlg4) 106942462

PMEI:

106908923 106923478(dlg4)

GAF:	122820906 122845071

PPRL:

129368887 129376598

CVG:	107093504 107104680

CTUL:

119776554 119778422

GMU:	124876270 124880704

NFU:	107374534 107386432

KMR:	108248807 108250468(dlg4b)

ALIM:

106526141(dlg4)

NWH:	119410206 119420314

AOCE:

111563200 111587179(dlg4)

MCEP:

125021153

CSEM:

103389793 103395581(dlg4)

POV:	109628693(dlg4)

SSEN:

122766796(dlg4b) 122779610

HHIP:

117774915

HSP:	118102960(dlg4b) 118122597

PPLT:

128430181(dlg4b) 128457591

SMAU:

118283926 118301323

LCF:	108874238 108893750

SDU:	111234292(dlg4) 111239738

SLAL:

111666249(dlg4)

XGL:	120797243(dlg4b) 120802403

HCQ:	109517978(dlg4) 109518216

SSCV:

125981942 125992118

SBIA:

133491996 133494479

PEE:	133398023 133415832

PTAO:

133467351 133472340

BPEC:

110158421(dlg4)

MALB:

109952440 109959428(dlg4)

BSPL:

114866919 114869057

SJO:	128371940 128384068(dlg4b)

SASA:

106563427 106603100

STRU:

115154735(dlg4) 115185814

OTW:	112228865 112231273 112242781

OMY:	110494899 110509418 110534036

OGO:	124007149 124007399

ONE:	115125410 115134938

OKI:	109872705 109874161 109886097

OKE:	118372037 118382146 118389715

SALP:

111963712

SNH:	120021063 120056608

CCLU:

121541887 121579527 123487221

ELS:	105009398 105010827

SFM:

108920348

PKI:	111836332 111839579(dlg4)

AANG:

118223749(dlg4b) 118236420

LOC:

102694789

PSPA:

121305653 121306537

PSEX:

120525084

LCM:	102364285(DLG4)

HOC:

LERI:

PCLA:

Reference

PMID:9286702

Authors

Stathakis DG, Hoover KB, You Z, Bryant PJ

Title

Human postsynaptic density-95 (PSD95): location of the gene (DLG4) and possible function in nonneural as well as in neural tissues.

Journal

Genomics 44:71-82 (1997)
DOI:10.1006/geno.1997.4848

Sequence

[hsa:1742]

Reference

PMID:11052931

Authors

Kennedy MB

Title

Signal-processing machines at the postsynaptic density.

Journal

Science 290:750-4 (2000)
DOI:10.1126/science.290.5492.750

Reference

PMID:15358863

Authors

Prange O, Wong TP, Gerrow K, Wang YT, El-Husseini A

Title

A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin.

Journal

Proc Natl Acad Sci U S A 101:13915-20 (2004)
DOI:10.1073/pnas.0405939101

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (754)   
   KEGG GENES (432)   
   KEGG MGENES (137)   
   RefGene (181)   
   OC (4)   
Literature (3)   
   PubMed (3)   
All databases (770)   

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