KEGG ORTHOLOGY: K12044

ORTHOLOGY: K12044

Entry

K12044                      KO

Symbol

TNNI3

Name

troponin I, cardiac muscle

Pathway

map04024

cAMP signaling pathway

map04260

Cardiac muscle contraction

map04261

Adrenergic signaling in cardiomyocytes

map04814

Motor proteins

map04820

Cytoskeleton in muscle cells

map05410

Hypertrophic cardiomyopathy

map05414

Dilated cardiomyopathy

map05415

Diabetic cardiomyopathy

Disease

H00292

Hypertrophic cardiomyopathy

H00294

Dilated cardiomyopathy

H01219

Restrictive cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K12044  TNNI3; troponin I, cardiac muscle
09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    K12044  TNNI3; troponin I, cardiac muscle
   04820 Cytoskeleton in muscle cells
    K12044  TNNI3; troponin I, cardiac muscle
09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12044  TNNI3; troponin I, cardiac muscle
   04261 Adrenergic signaling in cardiomyocytes
    K12044  TNNI3; troponin I, cardiac muscle
09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
   05414 Dilated cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
   05415 Diabetic cardiomyopathy
    K12044  TNNI3; troponin I, cardiac muscle
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12044  TNNI3; troponin I, cardiac muscle
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Troponins
     K12044  TNNI3; troponin I, cardiac muscle

Other DBs

GO:	0030172 0031014

Genes

HSA:	7137(TNNI3)

PTR:	735514(TNNI3)

PPS:	100987819(TNNI3)

GGO:	101137001(TNNI3)

PON:	100173211(TNNI3)

PPYG:

129020045(TNNI3)

NLE:	100590739(TNNI3)

HMH:	116479209(TNNI3)

SSYN:

129460354(TNNI3)

MCC:	698470(TNNI3)

MCF:	102122269(TNNI3)

MTHB:

126943251

MNI:	105496973(TNNI3)

CSAB:

103235292(TNNI3)

CATY:

105582742(TNNI3)

PANU:

101018203(TNNI3)

TGE:	112612647(TNNI3)

MLEU:

105551621(TNNI3)

RRO:	104674758(TNNI3)

RBB:	108542529(TNNI3)

TFN:	117091726(TNNI3)

PTEH:

111521182(TNNI3)

CANG:

105504870(TNNI3)

CJC:	100389415(TNNI3)

SBQ:	101046410(TNNI3)

CIMI:

108316608(TNNI3)

ANAN:

105726009(TNNI3)

CSYR:

103267496(TNNI3)

MMUR:

105877194(TNNI3)

LCAT:

123624691(TNNI3)

PCOQ:

105809240(TNNI3)

OGA:	100941332(TNNI3)

MMU:	21954(Tnni3)

MCAL:

110298605(Tnni3)

MPAH:

110336690(Tnni3)

RNO:	29248(Tnni3)

MCOC:

116101548(Tnni3)

ANU:	117701209(Tnni3)

MUN:	110561052(Tnni3)

CGE:

113837253

MAUA:

101830909(Tnni3)

PROB:

127238799(Tnni3)

PLEU:

114689156(Tnni3)

MORG:

121449614(Tnni3)

MFOT:

126493689

AAMP:

119821433(Tnni3)

NGI:	103744862(Tnni3)

HGL:	101711288(Tnni3)

CPOC:

100718375(Tnni3)

CCAN:

109696273(Tnni3)

DORD:

105999533(Tnni3)

DSP:	122110728(Tnni3)

PLOP:

125339094(Tnni3)

NCAR:

124966930

MMMA:

107158858(Tnni3)

OPI:	101533210(TNNI3)

TUP:	102497806(TNNI3)

GVR:	103594698(TNNI3)

CFA:	403566(TNNI3)

CLUD:

112645006(TNNI3)

VVP:	112909344(TNNI3)

VLG:	121484903(TNNI3)

NPO:	129500670(TNNI3)

AML:	100471638(TNNI3)

ELK:

111140065

LLV:

125089169

MPUF:

106003394(TNNI3)

MNP:	132005525(TNNI3)

MLK:	131818809(TNNI3)

NVS:	122913412(TNNI3)

ORO:	101384802(TNNI3)

MLX:	117997899(TNNI3)

NSU:	110573755(TNNI3)

LWW:	102748786(TNNI3)

FCA:	493744(TNNI3)

PYU:	121023342(TNNI3)

PCOO:

112850925(TNNI3)

PBG:	122493744(TNNI3)

PVIV:

125153309(TNNI3)

LRUF:

124527752

PTG:	102964327(TNNI3)

PPAD:

109259919(TNNI3)

PUC:	125917309 125918195

AJU:

106980877

HHV:	120239760(TNNI3)

BTA:	511094(TNNI3)

BOM:	102271644(TNNI3)

BIU:	109572857(TNNI3)

BBUB:

102413284(TNNI3)

BBIS:

104995380(TNNI3)

CHX:	100860775(TNNI3)

OAS:	101121961(TNNI3)

BTAX:

128063310(TNNI3)

ODA:	120871909(TNNI3)

CCAD:

122420142(TNNI3)

MBEZ:

129546031(TNNI3)

SSC:	100049696(TNNI3)

CFR:	102512551(TNNI3)

CBAI:

105074354(TNNI3)

CDK:	105098776(TNNI3)

VPC:	102524999(TNNI3)

BACU:

103008175(TNNI3)

BMUS:

118885634(TNNI3)

LVE:	103083728(TNNI3)

OOR:	101276056(TNNI3)

DLE:	111181027(TNNI3)

PCAD:

102986127(TNNI3)

PSIU:

116743854(TNNI3)

NASI:

112406404(TNNI3)

ECB:	100034065(TNNI3)

EPZ:	103562864(TNNI3)

EAI:	106840925(TNNI3)

MYD:	102759613(TNNI3)

MMYO:

118655187(TNNI3)

PKL:	118715922(TNNI3)

EFUS:

103303378(TNNI3)

MNA:	107541326(TNNI3)

DRO:	112313852(TNNI3)

SHON:

118981346(TNNI3)

AJM:	119059954(TNNI3)

PDIC:

114510713(TNNI3)

PHAS:

123813365(TNNI3)

MMF:	118638764(TNNI3)

PPAM:

129082456(TNNI3)

HAI:	109373796(TNNI3)

RFQ:	117034883(TNNI3)

PALE:

102889585(TNNI3)

PGIG:

120598385(TNNI3)

PVP:	105304920(TNNI3)

RAY:	107515439(TNNI3)

MJV:	108396327(TNNI3)

TOD:	119250476(TNNI3)

SARA:

101539366(TNNI3)

SETR:

126028716(TNNI3)

TMU:

101356235

ETF:	101648930(TNNI3)

DNM:	105745722(TNNI3)

MDO:	100032908(TNNI3)

GAS:	123240829 123255799

SHR:	116422945(TNNI3)

AFZ:

127556700

PCW:	110220013(TNNI3)

TVP:	118837557(TNNI3)

OAA:	100077614(TNNI3)

PCOC:

116239621(TNNI3)

MGP:	100303672(TNNI3)

CJO:

107307234

NMEL:

110391348(TNNI3)

LSR:

PMOA:

PHI:

CCAE:

NNI:

ASN:	102377294(TNNI3)

AMJ:	102575200(TNNI3)

CMY:	119564848(TNNI3)

CCAY:

125627902(TNNI3)

DCC:	119847253(TNNI3)

CPIC:

101942367(TNNI3)

CABI:

116840096(TNNI3)

MRV:	120388345(TNNI3)

ACS:	100564471(tnni3)

ASAO:

132779383(TNNI3)

PVT:	110078530(TNNI3)

SUND:

121932466(TNNI3)

PBI:	103063845(TNNI3)

PMUR:

107282457(TNNI3) 107298483

CTIG:

120304515(TNNI3)

TSR:

106538688

PGUT:

117669099(TNNI3)

APRI:

131198085(TNNI3)

PTEX:

113443669(TNNI3)

NSS:	113418613(TNNI3)

VKO:	123032274(TNNI3)

PMUA:

114582228(TNNI3)

PRAF:

128400990(TNNI3)

ZVI:	118095851(TNNI3)

HCG:	128329908(TNNI3)

GJA:	107118434(TNNI3)

STOW:

125445236(TNNI3)

EMC:	129339519(TNNI3)

XLA:	397803(tnni3.S) 494826(tnni3.L)

XTR:	496889(tnni3)

NPR:	108794936(TNNI3)

RTEM:

120915351(TNNI3)

BBUF:

121001385(TNNI3)

BGAR:

122928655(TNNI3)

MUO:	115465016(TNNI3)

GSH:	117368312(TNNI3)

LCM:	102364336(TNNI3)

SCLV:

120331139

DER:

6550283

DSI:	Dsimw501_GD24482(Dsim_GD24482)

DYA:	Dyak_GE15552(Dyak_wupA)

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI14711

DAZ:

108618682

DNV:	108656035 115565621

MDE:

LCQ:

AGA:

ACOZ:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ014296

CPII:

120420188

BCOO:

119079901

AME:	410815(TpnI)

BIM:

BTER:

CCAL:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

FEX:

PGC:

OBO:

PCF:

VVE:

NVI:

MDL:	103569650 103577941

CCIN:

TCA:

DPA:

ATD:

AGB:

DVV:

NVL:

BMOR:

692734(TpnI)

BMAN:

114252543

MSEX:

115446640

DPL:	KGM_209334

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

AAGE:

HAW:	110371854(wupA)

HZE:

SLIU:

OFU:

ATRA:

GMW:

PXY:

LGLY:

API:

BTAB:

CLEC:

PHU:	Phum_PHUM503610

ZNE:	110826525 110840873

CSEC:

111863749

BROR:

134532100

EAF:

111715703

TUT:	107363306 107365618 107370019

DPTE:

113799619

CSCU:

111640285

ABRU:

129966587

BMY:	BM_BM7540(Bm7540)

LOA:	LOAG_08015

TSP:

Tsp_09119

» show all

Reference

PMID:22876777

Authors

Rani DS, Nallari P, Priyamvada S, Narasimhan C, Singh L, Thangaraj K

Title

High prevalence of Arginine to Glutamine Substitution at 98, 141 and 162 positions in Troponin I (TNNI3) associated with hypertrophic cardiomyopathy among Indians.

Journal

BMC Med Genet 13:69 (2012)
DOI:10.1186/1471-2350-13-69

Sequence

[hsa:7137]

Reference

PMID:2226790

Authors

Vallins WJ, Brand NJ, Dabhade N, Butler-Browne G, Yacoub MH, Barton PJ

Title

Molecular cloning of human cardiac troponin I using polymerase chain reaction.

Journal

FEBS Lett 270:57-61 (1990)
DOI:10.1016/0014-5793(90)81234-f

Sequence

[hsa:7137]

All links

Ontology (4)   
   KEGG BRITE (2)   
   GO (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (1)   
   KEGG DRUG (1)   
Gene (377)   
   KEGG GENES (285)   
   KEGG MGENES (13)   
   RefGene (78)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (403)   

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