Entry |
|
Name |
5-guanidino-2-oxopentanoate decarboxylase;
alpha-ketoarginine decarboxylase;
2-oxo-5-guanidinopentanoate carboxy-lyase
|
Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
|
Sysname |
5-guanidino-2-oxopentanoate carboxy-lyase (4-guanidinobutanal-forming)
|
Reaction(IUBMB) |
5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2 [RN: R03178]
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Reaction(KEGG) |
|
Substrate |
5-guanidino-2-oxopentanoate [CPD: C03771]
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Product |
|
Comment |
Enzyme activity is dependent on the presence of thiamine diphosphate and a divalent cation.
|
History |
EC 4.1.1.75 created 1999
|
Pathway |
ec00330 | Arginine and proline metabolism |
|
Orthology |
K12253 | 5-guanidino-2-oxopentanoate decarboxylase |
|
Genes |
» show all
|
Reference |
|
Authors |
Vanderbilt AS, Gaby NS, Rodwell VW. |
Title |
Intermediates and enzymes between alpha-ketoarginine and gamma-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida. |
Journal |
J Biol Chem 250:5322-9 (1975) |
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.75 |
ExPASy - ENZYME nomenclature database: | 4.1.1.75 |
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