KEGG   ORTHOLOGY: K12253
Entry
K12253                      KO                                     

Name
aruI
Definition
5-guanidino-2-oxopentanoate decarboxylase [EC:4.1.1.75]
Pathway
ko00330  Arginine and proline metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K12253  aruI; 5-guanidino-2-oxopentanoate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.75  5-guanidino-2-oxopentanoate decarboxylase
     K12253  aruI; 5-guanidino-2-oxopentanoate decarboxylase
Other DBs
RN: R03178
COG: COG0028
GO: 0047435
Genes
PAE: PA4977(aruI)
PAEV: N297_5149
PAEI: N296_5149
PAU: PA14_65795
PAP: PSPA7_5710
PAG: PLES_53651(aruI)
PNC: NCGM2_0541
PAEB: NCGM1900_5725
PDK: PADK2_26375
PSG: G655_26230
PRP: M062_26240
PAEP: PA1S_26995
PAER: PA1R_gp2900
PAEM: U769_27260
PAEL: T223_27455
PAES: SCV20265_5640
PAEG: AI22_07000
PAEC: M802_5147
PAEO: M801_5014
PRE: PCA10_40350
PCQ: PcP3B5_02220(aruI_1)
PPU: PP_3723(aruI)
PPF: Pput_2040
PPG: PputGB1_2183
PPT: PPS_3191
PPB: PPUBIRD1_2039
PPI: YSA_09434
PPX: T1E_1730
PPUH: B479_15835
PPUT: L483_19375
PPUN: PP4_20990
PPUD: DW66_3462
PMON: X969_15345
PMOT: X970_14990
PPJ: RK21_01447
PFL: PFL_2714
PPRC: PFLCHA0_c27750(ilvB1)
PPRO: PPC_2761(aruI)
PMAN: OU5_1976
PTV: AA957_03675
PAZO: AYR47_18015
PFW: PF1751_v1c20110
PFF: PFLUOLIPICF726665
PFX: A7318_09785
PPUU: PputUW4_02749
PDR: H681_24935
PSK: U771_11345
PKC: PKB_0123
PCZ: PCL1606_34610
PALK: PSAKL28_23950
PSEM: TO66_13285
PSOS: POS17_2710(aruI)
PANR: A7J50_2200
PSET: THL1_3998
PYM: AK972_2095
PUM: HGP31_15875
POJ: PtoMrB4_51010(aruI)
COLW: A3Q33_05685
CBER: B5D82_00660
MICC: AUP74_02851(aruI_1)
MAGA: Mag101_09645
MHYD: GTQ55_10570
SIX: BSY16_6046
SHZ: shn_17240
NOH: G5V57_06975
RUA: D1823_07575
RUT: FIU92_05590(ilvG)
RDE: RD1_1943(ilvB)
RLI: RLO149_c010380
RPON: G3256_13050
OAT: OAN307_c15390
OAR: OA238_c27100
OTM: OSB_09640(aruI)
OCT: FTO60_10835
PTP: RCA23_c27460
SUAM: BOO69_05960
SPSE: SULPSESMR1_00851(aruI)
SULZ: C1J03_15970
SULI: C1J05_05650
SPOT: G6548_11780
TOM: BWR18_04905
RMM: ROSMUCSMR3_00989(aruI)
ROK: RAK1035_3857
RID: RIdsm_03467(aruI)
ROM: EI983_05210
ROH: FIU89_06845(aruI)
AHT: ANTHELSMS3_04191(aruI)
SAGU: CDO87_17335
THAA: CFI11_16070
PAED: G5B38_11405
MALU: KU6B_35330(aruI)
PAMO: BAR1_13645
SECH: B18_10960
SPHT: K426_15955
HTQ: FRZ44_22350(aruI)
HADH: FRZ61_24760(aruI)
BTS: Btus_2445
KYR: CVV65_12220
TMR: Tmar_0213
THEF: E1B22_04660
THEP: DYI95_000885
NTH: Nther_1932
AAR: Acear_1212
MDX: BTO20_17675
SALU: DC74_6010 DC74_661
SALL: SAZ_03825 SAZ_31125
SLC: SL103_18460
MIP: AXH82_05260
MOY: CVS54_03500(aruI)
AGY: ATC03_03680
LEU: Leucomu_03870 Leucomu_11420
LTR: EVS81_03935 EVS81_04360
LEB: G7066_00485 G7066_04190
AGG: C1N71_00685
ARE: AL755_01895
ACRY: AC20117_15030
KRH: KRH_21370
KFV: AS188_00300 AS188_05060
KII: KocCE7_11605
KRS: EQG70_15495
KOD: HBK84_11540
KVR: CIB50_0000905(aruI)
BLY: A2T55_12860
MPH: MLP_52890
PSIM: KR76_17655
TCU: Tcur_0450
NML: Namu_2951
GOB: Gobs_3087
AMQ: AMETH_5699(ilvB)
AAB: A4R43_27960
AMYY: YIM_01385(aruI1)
PDX: Psed_4489
AMS: AMIS_24950
VER: HUT12_14960
PLIM: PHILAsVB114_04455
ABAM: B1s21122_02855
CWO: Cwoe_4926
TRO: trd_0363
TLI: Tlie_1792
MOX: DAMO_0156
HALN: B4589_001925
 » show all
Reference
  Authors
Yang Z, Lu CD
  Title
Functional genomics enables identification of genes of the arginine transaminase pathway in Pseudomonas aeruginosa.
  Journal
J Bacteriol 189:3945-53 (2007)
DOI:10.1128/JB.00261-07
  Sequence
[pae:PA4977]

  All links  
Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1307)   
   KEGG GENES (147)   
   KEGG MGENES (1048)   
   RefGene (109)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (1319)   

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KEGG   ENZYME: 4.1.1.75
Entry
EC 4.1.1.75                 Enzyme                                 

Name
5-guanidino-2-oxopentanoate decarboxylase;
alpha-ketoarginine decarboxylase;
2-oxo-5-guanidinopentanoate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
5-guanidino-2-oxopentanoate carboxy-lyase (4-guanidinobutanal-forming)
Reaction(IUBMB)
5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2 [RN:R03178]
Reaction(KEGG)
R03178
Substrate
5-guanidino-2-oxopentanoate [CPD:C03771]
Product
4-guanidinobutanal [CPD:C02647];
CO2 [CPD:C00011]
Comment
Enzyme activity is dependent on the presence of thiamine diphosphate and a divalent cation.
History
EC 4.1.1.75 created 1999
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K12253  5-guanidino-2-oxopentanoate decarboxylase
Genes
PAE: PA4977(aruI)
PAEV: N297_5149
PAEI: N296_5149
PAU: PA14_65795
PAP: PSPA7_5710
PAG: PLES_53651(aruI)
PNC: NCGM2_0541
PAEB: NCGM1900_5725
PDK: PADK2_26375
PSG: G655_26230
PRP: M062_26240
PAEP: PA1S_26995
PAER: PA1R_gp2900
PAEM: U769_27260
PAEL: T223_27455
PAES: SCV20265_5640
PAEG: AI22_07000
PAEC: M802_5147
PAEO: M801_5014
PRE: PCA10_40350
PCQ: PcP3B5_02220(aruI_1)
PPU: PP_3723(aruI)
PPF: Pput_2040
PPG: PputGB1_2183
PPT: PPS_3191
PPB: PPUBIRD1_2039
PPI: YSA_09434
PPX: T1E_1730
PPUH: B479_15835
PPUT: L483_19375
PPUN: PP4_20990
PPUD: DW66_3462
PMON: X969_15345
PMOT: X970_14990
PPJ: RK21_01447
PFL: PFL_2714
PPRC: PFLCHA0_c27750(ilvB1)
PPRO: PPC_2761(aruI)
PMAN: OU5_1976
PTV: AA957_03675
PAZO: AYR47_18015
PFW: PF1751_v1c20110
PFF: PFLUOLIPICF726665
PFX: A7318_09785
PPUU: PputUW4_02749
PDR: H681_24935
PSK: U771_11345
PKC: PKB_0123
PCZ: PCL1606_34610
PALK: PSAKL28_23950
PSEM: TO66_13285
PSOS: POS17_2710(aruI)
PANR: A7J50_2200
PSET: THL1_3998
PYM: AK972_2095
PUM: HGP31_15875
POJ: PtoMrB4_51010(aruI)
COLW: A3Q33_05685
CBER: B5D82_00660
MICC: AUP74_02851(aruI_1)
MAGA: Mag101_09645
MHYD: GTQ55_10570
SIX: BSY16_6046
SHZ: shn_17240
NOH: G5V57_06975
RUA: D1823_07575
RUT: FIU92_05590(ilvG)
RDE: RD1_1943(ilvB)
RLI: RLO149_c010380
RPON: G3256_13050
OAT: OAN307_c15390
OAR: OA238_c27100
OTM: OSB_09640(aruI)
OCT: FTO60_10835
PTP: RCA23_c27460
SUAM: BOO69_05960
SPSE: SULPSESMR1_00851(aruI)
SULZ: C1J03_15970
SULI: C1J05_05650
SPOT: G6548_11780
TOM: BWR18_04905
RMM: ROSMUCSMR3_00989(aruI)
ROK: RAK1035_3857
RID: RIdsm_03467(aruI)
ROM: EI983_05210
ROH: FIU89_06845(aruI)
AHT: ANTHELSMS3_04191(aruI)
SAGU: CDO87_17335
THAA: CFI11_16070
PAED: G5B38_11405
MALU: KU6B_35330(aruI)
PAMO: BAR1_13645
SECH: B18_10960
SPHT: K426_15955
HTQ: FRZ44_22350(aruI)
HADH: FRZ61_24760(aruI)
BTS: Btus_2445
KYR: CVV65_12220
TMR: Tmar_0213
THEF: E1B22_04660
THEP: DYI95_000885
NTH: Nther_1932
AAR: Acear_1212
MDX: BTO20_17675
SALU: DC74_6010 DC74_661
SALL: SAZ_03825 SAZ_31125
SLC: SL103_18460
MIP: AXH82_05260
MOY: CVS54_03500(aruI)
AGY: ATC03_03680
LEU: Leucomu_03870 Leucomu_11420
LTR: EVS81_03935 EVS81_04360
LEB: G7066_00485 G7066_04190
AGG: C1N71_00685
ARE: AL755_01895
ACRY: AC20117_15030
KRH: KRH_21370
KFV: AS188_00300 AS188_05060
KII: KocCE7_11605
KRS: EQG70_15495
KOD: HBK84_11540
KVR: CIB50_0000905(aruI)
BLY: A2T55_12860
MPH: MLP_52890
PSIM: KR76_17655
TCU: Tcur_0450
NML: Namu_2951
GOB: Gobs_3087
AMQ: AMETH_5699(ilvB)
AAB: A4R43_27960
AMYY: YIM_01385(aruI1)
PDX: Psed_4489
AMS: AMIS_24950
VER: HUT12_14960
PLIM: PHILAsVB114_04455
ABAM: B1s21122_02855
CWO: Cwoe_4926
TRO: trd_0363
TLI: Tlie_1792
MOX: DAMO_0156
HALN: B4589_001925
 » show all
Reference
1  [PMID:237915]
  Authors
Vanderbilt AS, Gaby NS, Rodwell VW.
  Title
Intermediates and enzymes between alpha-ketoarginine and gamma-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida.
  Journal
J Biol Chem 250:5322-9 (1975)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.75
IUBMB Enzyme Nomenclature: 4.1.1.75
ExPASy - ENZYME nomenclature database: 4.1.1.75
BRENDA, the Enzyme Database: 4.1.1.75
CAS: 56831-67-5

  All links  
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (1305)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (147)   
   KEGG MGENES (1048)   
   RefGene (109)   
Protein sequence (2865)   
   UniProt (887)   
   SWISS-PROT (1)   
   RefSeq(pep) (1977)   
DNA sequence (2966)   
   RefSeq(nuc) (2500)   
   GenBank (246)   
   EMBL (220)   
Protein domain (6)   
   InterPro (6)   
All databases (7151)   

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KEGG   REACTION: R03178
Entry
R03178                      Reaction                               

Name
2-oxo-5-Guanidinopentanoate carboxy-lyase
Definition
5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2
Equation
Reaction class
RC00506  C02647_C03771
Enzyme
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Orthology
K12253  5-guanidino-2-oxopentanoate decarboxylase [EC:4.1.1.75]
Other DBs
RHEA: 11343

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (148)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (147)   
All databases (158)   

Download RDF
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