KEGG   ORTHOLOGY: K12253
Entry
K12253                      KO                                     
Symbol
aruI
Name
5-guanidino-2-oxopentanoate decarboxylase [EC:4.1.1.75]
Pathway
map00330  Arginine and proline metabolism
map01100  Metabolic pathways
Reaction
R03178  2-oxo-5-guanidinopentanoate carboxy-lyase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00330 Arginine and proline metabolism
    K12253  aruI; 5-guanidino-2-oxopentanoate decarboxylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.75  5-guanidino-2-oxopentanoate decarboxylase
     K12253  aruI; 5-guanidino-2-oxopentanoate decarboxylase
Other DBs
COG: COG0028
GO: 0047435
Genes
PRE: PCA10_40350
PFUW: KF707C_17620
POJ: PtoMrB4_51010(aruI)
PLAL: FXN65_08190
PAE: PA4977(aruI)
PAEV: N297_5149
PAEI: N296_5149
PAU: PA14_65795
PAG: PLES_53651(aruI)
PNC: NCGM2_0541
PAEB: NCGM1900_5725
PDK: PADK2_26375
PSG: G655_26230
PRP: M062_26240
PAEP: PA1S_26995
PAER: PA1R_gp2900
PAEM: U769_27260
PAEL: T223_27455
PAES: SCV20265_5640
PAEG: AI22_07000
PAEC: M802_5147
PAEO: M801_5014
SECH: B18_10960
PCQ: PcP3B5_02220(aruI_1)
PMUI: G4G71_03195
PNT: G5B91_32205
PAP: PSPA7_5710
PPU: PP_3723(aruI)
PPF: Pput_2040
PPG: PputGB1_2183
PPT: PPS_3191
PPB: PPUBIRD1_2039
PPI: YSA_09434
PPX: T1E_1730
PPUH: B479_15835
PPUT: L483_19375
PPUN: PP4_20990
PPUD: DW66_3462
PMON: X969_15345
PMOT: X970_14990
PPJ: RK21_01447
PALD: LU682_011575
PIX: RIN61_01165
PFL: PFL_2714
PPRC: PFLCHA0_c27750(ilvB1)
PPRO: PPC_2761(aruI)
PMAN: OU5_1976
PTV: AA957_03675
PAZO: AYR47_18015
PTOL: I7845_10660
PFW: PF1751_v1c20110
PFF: PFLUOLIPICF726665
PFX: A7318_09785
PPUU: PputUW4_02749
PDR: H681_24935
PSK: U771_11345
PKC: PKB_0123
PCZ: PCL1606_34610
PCHP: C4K32_2706
PALK: PSAKL28_23950
PSEM: TO66_13285
PSOS: POS17_2710(aruI)
PANR: A7J50_2200
PSET: THL1_3998
PYM: AK972_2095
PUM: HGP31_15875
PMAO: PMYSY11_3759(aruI)
PDW: BV82_5126
PSEP: C4K39_2739
PPII: QL104_17235
PVW: HU752_013320
PAZE: KSS91_15430
PORY: EJA05_15315
PTK: EXN22_14855
PWY: HU734_015265
PTAE: NCTC10697_02326(ilvB_2)
PCAV: D3880_08970
PIZ: LAB08_R27900
PPEG: KUA23_18865
PSIH: LOY51_15675
PASI: LG197_21545
PKM: PZ739_16625
PNB: NK667_09515
PTAI: ICN73_22465
PKK: QQ992_10575
PKJ: Q1W70_23970
PHOM: KJF94_09170
PTRL: OU419_28455
PSJY: AA098_17130
PSNC: C0058_12330
PFOU: OZ911_17045
PSKP: KU43P_29790(aruI)
PBAM: NUH87_05425
PCAA: V6L78_22975
PSWO: SD196_27195
PMOR: PMm318_A41730
PSSX: DCC84_13265
PSNS: CI807_17545
PDEN: F1C79_24145
COLW: A3Q33_05685
CBER: B5D82_00660
MICC: AUP74_02851(aruI_1)
MAGA: Mag101_09645
MHYD: GTQ55_10570
SIX: BSY16_6046
RHIA: ACO34A_28085
SHZ: shn_17240
SSUM: Q9314_27100
NOH: G5V57_06975
RUA: D1823_07575
RUT: FIU92_05590(ilvG)
RCON: K3740_06455
RUY: NOR97_05565
RDE: RD1_1943(ilvB)
RLI: RLO149_c010380
RPON: G3256_13050
RFU: ROLI_008540(aruI)
OAT: OAN307_c15390
OAR: OA238_c27100
OTM: OSB_09640(aruI)
OCT: FTO60_10835
SUAM: BOO69_05960
SULZ: C1J03_15970
SULI: C1J05_05650
SPOT: G6548_11780
SMED: JNX03_06855
SUAL: KDD17_03895
SULB: IV89_001371
SULY: ABM428_11490
SULP: AADW22_11925
SUSQ: K3756_11900
SPSE: SULPSESMR1_00851(aruI)
TOM: BWR18_04905
RMM: ROSMUCSMR3_00989(aruI)
ROK: RAK1035_3857
RID: RIdsm_03467(aruI)
ROM: EI983_05210
ROH: FIU89_06845(aruI)
RPEL: N7U68_12610
RPHC: RZ517_07195
RRL: RZS32_000925
AHT: ANTHELSMS3_04191(aruI)
SAGU: CDO87_17335
SSTL: ABFK29_08490
THAA: CFI11_16070
MALU: KU6B_35330(aruI)
TRY: QF118_10155
ASCA: QEZ52_05455 QEZ52_07675
ACLD: ACIRQ6_11725
MATG: ACMVPR_01695
PTP: RCA23_c27460
YPHY: AABB29_11165
YAG: AABB28_02325
YRH: AABB31_11595
PAED: G5B38_11405
PAMO: BAR1_13645
CACT: HZ995_02610
ACRO: K3J57_10185
AALK: LGT41_0009545
AMYL: QBD29_12200
LVR: T8T21_07515
BOSG: GKR98_16850
SPHT: K426_15955
SKT: IGS68_03240
HTQ: FRZ44_22350(aruI)
HADH: FRZ61_24760(aruI)
NACI: NUH88_06265
TRO: trd_0363
BTS: Btus_2445
KYR: CVV65_12220
ALKA: J0B03_10680
TMR: Tmar_0213
THEF: E1B22_04660
THEP: DYI95_000885
NTH: Nther_1932
AAR: Acear_1212
SLC: SL103_18460
SCAD: DN051_41845
SALU: DC74_6010 DC74_661
SALL: SAZ_03825 SAZ_31125
MIP: AXH82_05260
MOY: CVS54_03500(aruI)
AGY: ATC03_03680
LEU: Leucomu_03870 Leucomu_11420
LTR: EVS81_04360
LEB: G7066_00485 G7066_04190
LVI: G7068_13330
LINS: G7067_05385 G7067_05435
LLUT: K1X41_11780 K1X41_12460
AGG: C1N71_00685
ARE: AL755_01895
ACRY: AC20117_15030
KRH: KRH_21370
KFV: AS188_05060
KII: KocCE7_11605
KRS: EQG70_15495
KOD: HBK84_11540
KVR: CIB50_0000905(aruI)
MPH: MLP_52890
TCU: Tcur_0450
NML: Namu_2951
GOB: Gobs_3087
AMQ: AMETH_5699(ilvB)
AAB: A4R43_27960
AMYY: YIM_01385(aruI1)
VER: HUT12_14960
ACTE: ACTI_50670(ilvB1)
PLIM: PHILAsVB114_04455
ABAM: B1s21122_02855
TLI: Tlie_1792
MOX: DAMO_0156
HALN: B4589_001925
 » show all
Reference
PMID:17416670
  Authors
Yang Z, Lu CD
  Title
Functional genomics enables identification of genes of the arginine transaminase pathway in Pseudomonas aeruginosa.
  Journal
J Bacteriol 189:3945-53 (2007)
DOI:10.1128/JB.00261-07
  Sequence
[pae:PA4977]

  All links  
Ontology (2)   
   GO (1)   
   COG (1)   
Gene (1618)   
   MGENES (1506)   
   RefGene (109)   
   OC (3)   
All databases (1620)   

Download RDF
KEGG   ENZYME: 4.1.1.75
Entry
EC 4.1.1.75                 Enzyme                                 
Name
5-guanidino-2-oxopentanoate decarboxylase;
alpha-ketoarginine decarboxylase;
2-oxo-5-guanidinopentanoate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
5-guanidino-2-oxopentanoate carboxy-lyase (4-guanidinobutanal-forming)
Reaction(IUBMB)
5-guanidino-2-oxopentanoate = 4-guanidinobutanal + CO2 [RN:R03178]
Reaction(KEGG)
R03178
Substrate
5-guanidino-2-oxopentanoate [CPD:C03771]
Product
4-guanidinobutanal [CPD:C02647];
CO2 [CPD:C00011]
Comment
Enzyme activity is dependent on the presence of thiamine diphosphate and a divalent cation.
History
EC 4.1.1.75 created 1999
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K12253  5-guanidino-2-oxopentanoate decarboxylase
Genes
PRE: PCA10_40350
PFUW: KF707C_17620
POJ: PtoMrB4_51010(aruI)
PLAL: FXN65_08190
PAE: PA4977(aruI)
PAEV: N297_5149
PAEI: N296_5149
PAU: PA14_65795
PAG: PLES_53651(aruI)
PNC: NCGM2_0541
PAEB: NCGM1900_5725
PDK: PADK2_26375
PSG: G655_26230
PRP: M062_26240
PAEP: PA1S_26995
PAER: PA1R_gp2900
PAEM: U769_27260
PAEL: T223_27455
PAES: SCV20265_5640
PAEG: AI22_07000
PAEC: M802_5147
PAEO: M801_5014
SECH: B18_10960
PCQ: PcP3B5_02220(aruI_1)
PMUI: G4G71_03195
PNT: G5B91_32205
PAP: PSPA7_5710
PPU: PP_3723(aruI)
PPF: Pput_2040
PPG: PputGB1_2183
PPT: PPS_3191
PPB: PPUBIRD1_2039
PPI: YSA_09434
PPX: T1E_1730
PPUH: B479_15835
PPUT: L483_19375
PPUN: PP4_20990
PPUD: DW66_3462
PMON: X969_15345
PMOT: X970_14990
PPJ: RK21_01447
PALD: LU682_011575
PIX: RIN61_01165
PFL: PFL_2714
PPRC: PFLCHA0_c27750(ilvB1)
PPRO: PPC_2761(aruI)
PMAN: OU5_1976
PTV: AA957_03675
PAZO: AYR47_18015
PTOL: I7845_10660
PFW: PF1751_v1c20110
PFF: PFLUOLIPICF726665
PFX: A7318_09785
PPUU: PputUW4_02749
PDR: H681_24935
PSK: U771_11345
PKC: PKB_0123
PCZ: PCL1606_34610
PCHP: C4K32_2706
PALK: PSAKL28_23950
PSEM: TO66_13285
PSOS: POS17_2710(aruI)
PANR: A7J50_2200
PSET: THL1_3998
PYM: AK972_2095
PUM: HGP31_15875
PMAO: PMYSY11_3759(aruI)
PDW: BV82_5126
PSEP: C4K39_2739
PPII: QL104_17235
PVW: HU752_013320
PAZE: KSS91_15430
PORY: EJA05_15315
PTK: EXN22_14855
PWY: HU734_015265
PTAE: NCTC10697_02326(ilvB_2)
PCAV: D3880_08970
PIZ: LAB08_R27900
PPEG: KUA23_18865
PSIH: LOY51_15675
PASI: LG197_21545
PKM: PZ739_16625
PNB: NK667_09515
PTAI: ICN73_22465
PKK: QQ992_10575
PKJ: Q1W70_23970
PHOM: KJF94_09170
PTRL: OU419_28455
PSJY: AA098_17130
PSNC: C0058_12330
PFOU: OZ911_17045
PSKP: KU43P_29790(aruI)
PBAM: NUH87_05425
PCAA: V6L78_22975
PSWO: SD196_27195
PMOR: PMm318_A41730
PSSX: DCC84_13265
PSNS: CI807_17545
PDEN: F1C79_24145
COLW: A3Q33_05685
CBER: B5D82_00660
MICC: AUP74_02851(aruI_1)
MAGA: Mag101_09645
MHYD: GTQ55_10570
SIX: BSY16_6046
RHIA: ACO34A_28085
SHZ: shn_17240
SSUM: Q9314_27100
NOH: G5V57_06975
RUA: D1823_07575
RUT: FIU92_05590(ilvG)
RCON: K3740_06455
RUY: NOR97_05565
RDE: RD1_1943(ilvB)
RLI: RLO149_c010380
RPON: G3256_13050
RFU: ROLI_008540(aruI)
OAT: OAN307_c15390
OAR: OA238_c27100
OTM: OSB_09640(aruI)
OCT: FTO60_10835
SUAM: BOO69_05960
SULZ: C1J03_15970
SULI: C1J05_05650
SPOT: G6548_11780
SMED: JNX03_06855
SUAL: KDD17_03895
SULB: IV89_001371
SULY: ABM428_11490
SULP: AADW22_11925
SUSQ: K3756_11900
SPSE: SULPSESMR1_00851(aruI)
TOM: BWR18_04905
RMM: ROSMUCSMR3_00989(aruI)
ROK: RAK1035_3857
RID: RIdsm_03467(aruI)
ROM: EI983_05210
ROH: FIU89_06845(aruI)
RPEL: N7U68_12610
RPHC: RZ517_07195
RRL: RZS32_000925
AHT: ANTHELSMS3_04191(aruI)
SAGU: CDO87_17335
SSTL: ABFK29_08490
THAA: CFI11_16070
MALU: KU6B_35330(aruI)
TRY: QF118_10155
ASCA: QEZ52_05455 QEZ52_07675
ACLD: ACIRQ6_11725
MATG: ACMVPR_01695
PTP: RCA23_c27460
YPHY: AABB29_11165
YAG: AABB28_02325
YRH: AABB31_11595
PAED: G5B38_11405
PAMO: BAR1_13645
CACT: HZ995_02610
ACRO: K3J57_10185
AALK: LGT41_0009545
AMYL: QBD29_12200
LVR: T8T21_07515
BOSG: GKR98_16850
SPHT: K426_15955
SKT: IGS68_03240
HTQ: FRZ44_22350(aruI)
HADH: FRZ61_24760(aruI)
NACI: NUH88_06265
TRO: trd_0363
BTS: Btus_2445
KYR: CVV65_12220
ALKA: J0B03_10680
TMR: Tmar_0213
THEF: E1B22_04660
THEP: DYI95_000885
NTH: Nther_1932
AAR: Acear_1212
SLC: SL103_18460
SCAD: DN051_41845
SALU: DC74_6010 DC74_661
SALL: SAZ_03825 SAZ_31125
MIP: AXH82_05260
MOY: CVS54_03500(aruI)
AGY: ATC03_03680
LEU: Leucomu_03870 Leucomu_11420
LTR: EVS81_04360
LEB: G7066_00485 G7066_04190
LVI: G7068_13330
LINS: G7067_05385 G7067_05435
LLUT: K1X41_11780 K1X41_12460
AGG: C1N71_00685
ARE: AL755_01895
ACRY: AC20117_15030
KRH: KRH_21370
KFV: AS188_05060
KII: KocCE7_11605
KRS: EQG70_15495
KOD: HBK84_11540
KVR: CIB50_0000905(aruI)
MPH: MLP_52890
TCU: Tcur_0450
NML: Namu_2951
GOB: Gobs_3087
AMQ: AMETH_5699(ilvB)
AAB: A4R43_27960
AMYY: YIM_01385(aruI1)
VER: HUT12_14960
ACTE: ACTI_50670(ilvB1)
PLIM: PHILAsVB114_04455
ABAM: B1s21122_02855
TLI: Tlie_1792
MOX: DAMO_0156
HALN: B4589_001925
 » show all
Reference
1  [PMID:237915]
  Authors
Vanderbilt AS, Gaby NS, Rodwell VW.
  Title
Intermediates and enzymes between alpha-ketoarginine and gamma-guanidinobutyrate in the L-arginine catabolic pathway of Pseudomonas putida.
  Journal
J Biol Chem 250:5322-9 (1975)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.75
IUBMB Enzyme Nomenclature: 4.1.1.75
ExPASy - ENZYME nomenclature database: 4.1.1.75
BRENDA, the Enzyme Database: 4.1.1.75
CAS: 56831-67-5

  All links  
Gene (1615)   
   MGENES (1506)   
   RefGene (109)   
Protein sequence (3267)   
   UniProt (908)   
   SWISS-PROT (1)   
   RefSeq(pep) (2358)   
DNA sequence (4747)   
   RefSeq(nuc) (3449)   
   GenBank (656)   
   EMBL (642)   
Protein domain (7)   
   InterPro (7)   
All databases (9636)   

Download RDF
KEGG   REACTION: R03178
Entry
R03178                      Reaction                               
Name
2-oxo-5-guanidinopentanoate carboxy-lyase
Definition
5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2
Equation
C03771 <=> C02647 + C00011
Reaction class
RC00506  C02647_C03771
Enzyme
4.1.1.75
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.75
     R03178  5-Guanidino-2-oxopentanoate <=> 4-Guanidinobutanal + CO2
Orthology
K12253  5-guanidino-2-oxopentanoate decarboxylase [EC:4.1.1.75]
Other DBs
RHEA: 11343

  All links  
No link information was found.
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